psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E68	L:L:P69	3.14	No	No	0	2	3
2	L:L:E68	L:L:V73	2.85	No	No	0	2	8
3	L:L:E68	R:R:K187	12.15	No	No	0	2	4
4	L:L:P69	R:R:K186	3.35	No	No	0	3	3
5	L:L:W72	R:R:E173	7.63	No	No	0	8	4
6	L:L:W72	R:R:T175	8.49	No	No	0	8	2
7	L:L:W72	R:R:K186	5.8	No	No	0	8	3
8	L:L:P75	L:L:V74	3.53	Yes	Yes	0	9	9
9	L:L:V74	R:R:K92	3.04	Yes	No	0	9	5
10	L:L:V74	R:R:Y182	15.14	Yes	No	0	9	3
11	L:L:V74	R:R:A184	5.09	Yes	No	0	9	3
12	L:L:P75	L:L:Q80	9.47	Yes	No	0	9	9
13	L:L:P75	R:R:R172	7.21	Yes	Yes	0	9	5
14	L:L:L78	L:L:P79	4.93	Yes	No	0	9	9
15	L:L:L78	R:R:M117	5.65	Yes	No	0	9	7
16	L:L:L78	R:R:F257	7.31	Yes	No	0	9	7
17	L:L:L78	R:R:F292	4.87	Yes	Yes	0	9	7
18	L:L:P79	R:R:S114	3.56	No	No	0	9	5
19	L:L:Q80	R:R:Q281	5.12	No	No	0	9	4
20	L:L:V81	R:R:K192	4.55	Yes	No	0	9	4
21	L:L:V81	R:R:S196	3.23	Yes	No	0	9	5
22	L:L:V81	R:R:I265	6.14	Yes	Yes	0	9	4
23	R:R:E93	R:R:P37	4.72	Yes	No	0	4	5
24	R:R:F39	R:R:V43	7.87	No	No	0	5	7
25	R:R:F39	R:R:P289	2.89	No	No	0	5	5
26	R:R:A293	R:R:F39	2.77	No	No	0	5	5
27	R:R:L86	R:R:Y40	9.38	No	Yes	6	8	7
28	R:R:E93	R:R:Y40	6.73	Yes	Yes	0	4	7
29	R:R:P289	R:R:Y40	6.95	No	Yes	0	5	7
30	R:R:F292	R:R:Y40	10.32	Yes	Yes	6	7	7
31	R:R:C296	R:R:V43	6.83	Yes	No	0	8	7
32	R:R:F44	R:R:L45	3.65	Yes	No	0	7	4
33	R:R:F44	R:R:V48	3.93	Yes	No	0	7	7
34	R:R:F44	R:R:L83	4.87	Yes	No	0	7	6
35	R:R:F44	R:R:P87	17.34	Yes	No	0	7	8
36	R:R:C296	R:R:T46	3.38	Yes	No	0	8	5
37	R:R:F300	R:R:T46	3.89	No	No	0	6	5
38	R:R:L52	R:R:V48	2.98	No	No	0	3	7
39	R:R:G50	R:R:P299	4.06	No	No	0	7	9
40	R:R:F80	R:R:N51	8.46	No	No	0	7	9
41	R:R:N51	R:R:P299	4.89	No	No	0	9	9
42	R:R:I313	R:R:V53	6.14	Yes	No	0	7	6
43	R:R:L54	R:R:L58	5.54	No	No	0	9	7
44	R:R:I73	R:R:M55	4.37	No	No	0	6	7
45	R:R:A57	R:R:I313	3.25	No	Yes	0	7	7
46	R:R:D69	R:R:L58	5.43	No	No	0	8	7
47	R:R:I73	R:R:L58	4.28	No	No	0	6	7
48	R:R:F60	R:R:H59	14.71	No	No	0	5	4
49	R:R:K61	R:R:P62	3.35	No	No	0	5	5
50	R:R:K61	R:R:Y308	10.75	No	No	0	5	6
51	R:R:A312	R:R:K61	4.82	No	No	0	6	5
52	R:R:D69	R:R:R65	9.53	No	No	0	8	7
53	R:R:I68	R:R:R66	3.76	Yes	No	0	8	7
54	R:R:R66	R:R:Y308	14.4	No	No	0	7	6
55	R:R:D130	R:R:L67	6.79	No	No	0	8	5
56	R:R:L67	R:R:R145	7.29	No	No	0	5	7
57	R:R:I68	R:R:I72	2.94	Yes	No	0	8	8
58	R:R:I68	R:R:M127	4.37	Yes	No	0	8	9
59	R:R:I70	R:R:Y151	7.25	No	No	0	6	4
60	R:R:C126	R:R:F71	4.19	No	Yes	0	7	7
61	R:R:D130	R:R:F71	4.78	No	Yes	0	8	7
62	R:R:A150	R:R:F71	2.77	No	Yes	0	8	7
63	R:R:C154	R:R:F71	2.79	No	Yes	0	7	7
64	R:R:I72	R:R:Y302	3.63	No	Yes	0	8	9
65	R:R:I73	R:R:N74	2.83	No	No	0	6	9
66	R:R:C154	R:R:N74	7.87	No	No	0	7	9
67	R:R:D79	R:R:L75	4.07	No	No	0	9	9
68	R:R:L124	R:R:L75	2.77	No	No	0	8	9
69	R:R:L75	R:R:N298	6.87	No	No	0	9	9
70	R:R:N116	R:R:S78	5.96	No	Yes	0	8	8
71	R:R:C119	R:R:S78	5.16	No	Yes	7	7	8
72	R:R:S78	R:R:W158	4.94	Yes	No	7	8	9
73	R:R:D79	R:R:S120	2.94	No	No	0	9	9
74	R:R:D79	R:R:S295	8.83	No	No	0	9	9
75	R:R:F80	R:R:V84	3.93	No	No	0	7	4
76	R:R:I81	R:R:V84	3.07	No	No	0	7	4
77	R:R:I81	R:R:N116	9.91	No	No	0	7	8
78	R:R:F82	R:R:I113	6.28	Yes	No	0	6	7
79	R:R:F82	R:R:N116	9.67	Yes	No	0	6	8
80	R:R:F292	R:R:F82	8.57	Yes	Yes	0	7	6
81	R:R:F82	R:R:S295	7.93	Yes	No	0	6	9
82	R:R:L83	R:R:L86	2.77	No	No	0	6	8
83	R:R:S109	R:R:T85	7.99	No	No	0	5	7
84	R:R:M112	R:R:T85	10.54	No	No	8	5	7
85	R:R:I113	R:R:T85	3.04	No	No	8	7	7
86	R:R:F292	R:R:L86	4.87	Yes	No	6	7	8
87	R:R:L88	R:R:T101	2.95	No	Yes	3	6	7
88	R:R:L105	R:R:L88	5.54	No	No	3	6	6
89	R:R:K92	R:R:W89	9.28	No	No	0	5	6
90	R:R:E93	R:R:W89	3.27	Yes	No	0	4	6
91	R:R:W89	R:R:W99	6.56	No	Yes	0	6	8
92	R:R:E93	R:R:V90	7.13	Yes	No	0	4	6
93	R:R:D91	R:R:W99	8.93	No	Yes	0	4	8
94	R:R:D91	R:R:R100	7.15	No	No	3	4	3
95	R:R:D91	R:R:T101	4.34	No	Yes	3	4	7
96	R:R:G97	R:R:K92	3.49	No	No	0	4	5
97	R:R:L98	R:R:S95	4.5	No	No	0	4	3
98	R:R:L105	R:R:W99	10.25	No	Yes	0	6	8
99	R:R:C106	R:R:W99	9.14	No	Yes	0	9	8
100	R:R:K180	R:R:W99	9.28	No	Yes	0	3	8
101	R:R:R100	R:R:T101	9.06	No	Yes	3	3	7
102	R:R:L105	R:R:T101	5.9	No	Yes	3	6	7
103	R:R:L174	R:R:S103	7.51	No	No	0	5	3
104	R:R:C106	R:R:R172	4.18	No	Yes	2	9	5
105	R:R:C106	R:R:C183	7.28	No	Yes	2	9	9
106	R:R:S110	R:R:T168	3.2	No	No	0	5	4
107	R:R:R172	R:R:S110	17.13	Yes	No	0	5	5
108	R:R:V115	R:R:Y111	8.83	No	Yes	0	6	6
109	R:R:G165	R:R:Y111	2.9	No	Yes	0	7	6
110	R:R:L166	R:R:Y111	3.52	No	Yes	0	4	6
111	R:R:L169	R:R:Y111	14.07	No	Yes	0	5	6
112	R:R:I113	R:R:M112	2.92	No	No	8	7	5
113	R:R:S114	R:R:T168	9.59	No	No	0	5	4
114	R:R:M117	R:R:W254	5.82	No	Yes	0	7	9
115	R:R:H118	R:R:L164	11.57	No	No	0	6	4
116	R:R:C119	R:R:W158	5.22	No	No	7	7	9
117	R:R:C119	R:R:S161	3.44	No	No	0	7	8
118	R:R:F204	R:R:V121	5.24	Yes	No	1	8	8
119	R:R:V121	R:R:W254	3.68	No	Yes	1	8	9
120	R:R:I157	R:R:L122	7.14	No	No	0	7	5
121	R:R:L122	R:R:T203	4.42	No	No	0	5	6
122	R:R:I157	R:R:L123	2.85	No	No	0	7	8
123	R:R:P207	R:R:T125	6.99	No	No	0	9	8
124	R:R:S210	R:R:T125	4.8	No	No	0	7	8
125	R:R:I211	R:R:T125	6.08	No	No	0	8	8
126	R:R:M127	R:R:R131	3.72	No	No	0	9	9
127	R:R:I211	R:R:S128	7.74	No	No	0	8	9
128	R:R:S128	R:R:Y215	10.17	No	Yes	0	9	9
129	R:R:R131	R:R:Y215	7.2	No	Yes	0	9	9
130	R:R:R131	R:R:Y302	3.09	No	Yes	0	9	9
131	R:R:V136	R:R:Y132	11.36	No	Yes	9	7	8
132	R:R:W137	R:R:Y132	5.79	Yes	Yes	9	6	8
133	R:R:C214	R:R:Y132	9.41	No	Yes	0	8	8
134	R:R:C217	R:R:Y132	4.03	No	Yes	0	4	8
135	R:R:L133	R:R:S141	10.51	No	No	0	6	5
136	R:R:A134	R:R:R145	4.15	No	No	0	8	7
137	R:R:I135	R:R:I218	2.94	No	No	0	8	8
138	R:R:V136	R:R:W137	3.68	No	Yes	9	7	6
139	R:R:V139	R:R:V140	3.21	No	No	0	5	5
140	R:R:R145	R:R:S141	6.59	No	No	0	7	5
141	R:R:K143	R:R:R142	4.95	No	No	0	3	5
142	R:R:D148	R:R:R146	15.48	No	No	10	4	6
143	R:R:C149	R:R:R146	9.75	No	No	10	4	6
144	R:R:C149	R:R:D148	3.11	No	No	10	4	4
145	R:R:I160	R:R:L163	4.28	No	No	0	4	4
146	R:R:E185	R:R:S171	12.94	No	No	0	5	5
147	R:R:C183	R:R:R172	2.79	Yes	Yes	2	9	5
148	R:R:K180	R:R:L174	7.05	No	No	2	3	5
149	R:R:C183	R:R:L174	3.17	Yes	No	2	9	5
150	R:R:I177	R:R:T175	4.56	No	No	4	1	2
151	R:R:P181	R:R:T175	6.99	Yes	No	4	4	2
152	R:R:D178	R:R:I177	5.6	No	No	4	1	1
153	R:R:I177	R:R:P181	3.39	No	Yes	4	1	4
154	R:R:D178	R:R:P181	3.22	No	Yes	4	1	4
155	R:R:C183	R:R:K180	3.23	Yes	No	2	9	3
156	R:R:P181	R:R:Y182	11.13	Yes	No	0	4	3
157	R:R:E185	R:R:K186	10.8	No	No	0	5	3
158	R:R:A188	R:R:K187	3.21	No	No	5	4	4
159	R:R:K187	R:R:L193	2.82	No	No	5	4	2
160	R:R:A188	R:R:K192	4.82	No	No	0	4	4
161	R:R:A188	R:R:L193	3.15	No	No	5	4	2
162	R:R:P190	R:R:T189	5.25	No	No	0	2	3
163	R:R:I265	R:R:L193	4.28	Yes	No	0	4	2
164	R:R:F262	R:R:L197	7.31	No	No	0	5	4
165	R:R:I265	R:R:L197	2.85	Yes	No	0	4	4
166	R:R:F202	R:R:V198	3.93	No	No	0	4	3
167	R:R:L200	R:R:N258	4.12	No	No	0	5	8
168	R:R:K261	R:R:L200	2.82	No	No	0	5	5
169	R:R:F205	R:R:I201	6.28	No	No	0	4	5
170	R:R:F204	R:R:W254	3.01	Yes	Yes	1	8	9
171	R:R:F204	R:R:N258	30.21	Yes	No	0	8	8
172	R:R:P207	R:R:V206	3.53	No	No	0	9	6
173	R:R:L208	R:R:L209	2.77	Yes	No	0	6	4
174	R:R:F250	R:R:I211	3.77	No	No	0	9	8
175	R:R:I243	R:R:Y215	8.46	No	Yes	0	7	9
176	R:R:V247	R:R:Y215	5.05	No	Yes	0	8	9
177	R:R:H225	R:R:Q228	6.18	No	No	11	6	3
178	R:R:H225	R:R:N233	11.48	No	No	11	6	4
179	R:R:K234	R:R:Y226	7.17	No	No	0	4	3
180	R:R:K237	R:R:Y226	3.58	No	No	0	5	3
181	R:R:N233	R:R:Q228	3.96	No	No	11	4	3
182	R:R:G230	R:R:N233	5.09	No	No	0	3	4
183	R:R:H232	R:R:K231	13.1	No	No	0	4	4
184	R:R:H232	R:R:K235	5.24	No	No	0	4	6
185	R:R:I242	R:R:K238	4.36	No	No	0	8	7
186	R:R:F305	R:R:I242	5.02	Yes	No	0	6	8
187	R:R:F250	R:R:W254	11.02	No	Yes	0	9	9
188	R:R:L251	R:R:L255	4.15	No	No	1	6	6
189	R:R:N294	R:R:S253	8.94	No	No	0	9	8
190	R:R:A291	R:R:W254	7.78	No	Yes	0	8	9
191	R:R:N294	R:R:W254	4.52	No	Yes	0	9	9
192	R:R:L255	R:R:P256	3.28	No	No	0	6	9
193	R:R:P256	R:R:S287	3.56	No	No	0	9	7
194	R:R:F257	R:R:K261	3.72	No	No	0	7	5
195	R:R:F257	R:R:M284	4.98	No	No	0	7	4
196	R:R:F260	R:R:G283	3.01	No	No	0	5	5
197	R:R:L269	R:R:V266	2.98	No	No	0	1	5
198	R:R:E272	R:R:R270	4.65	No	No	0	1	1
199	R:R:E272	R:R:Y274	14.59	No	No	0	1	6
200	R:R:L275	R:R:P276	3.28	No	Yes	0	1	2
201	R:R:I279	R:R:P276	3.39	No	Yes	0	3	2
202	R:R:L280	R:R:P276	3.28	No	Yes	0	4	2
203	R:R:L280	R:R:M284	2.83	No	No	0	4	4
204	R:R:G288	R:R:P289	4.06	No	No	0	5	5
205	R:R:N298	R:R:Y302	5.81	No	Yes	0	9	9
206	R:R:F305	R:R:I301	3.77	Yes	No	0	6	8
207	R:R:I304	R:R:Y303	4.84	No	No	0	7	7
208	R:R:I313	R:R:Y303	6.04	Yes	No	0	7	7
209	R:R:F305	R:R:I304	8.79	Yes	No	0	6	7
210	R:R:I304	R:R:R310	3.76	No	No	0	7	8
211	R:R:D306	R:R:I309	8.4	No	No	0	8	8
212	R:R:R311	R:R:S307	5.27	No	No	0	5	4
213	R:R:H118	R:R:T203	2.74	No	No	0	6	6
214	R:R:C162	R:R:Y111	2.69	No	Yes	0	4	6
215	L:L:A77	R:R:Y40	2.67	No	Yes	0	9	7
216	R:R:F260	R:R:S287	2.64	No	No	0	5	7
217	R:R:R142	R:R:V139	2.62	No	No	0	5	5
218	R:R:H225	R:R:L236	2.57	No	No	0	6	7
219	R:R:V246	R:R:Y215	2.52	No	Yes	0	8	9
220	R:R:F71	R:R:I68	2.51	Yes	Yes	0	7	8
221	R:R:F202	R:R:I201	2.51	No	No	0	4	5
222	R:R:F262	R:R:I201	2.51	No	No	0	5	5
223	R:R:F305	R:R:I245	2.51	Yes	No	0	6	5
224	R:R:T147	R:R:Y151	2.5	No	No	0	3	4
225	R:R:E272	R:R:H273	2.46	No	No	0	1	4
226	R:R:F159	R:R:L163	2.44	No	No	0	4	4
227	R:R:F204	R:R:L208	2.44	Yes	Yes	1	8	6
228	R:R:F250	R:R:L208	2.44	No	Yes	0	9	6
229	R:R:I218	R:R:Y132	2.42	No	Yes	0	8	8
230	R:R:I309	R:R:Y302	2.42	No	Yes	0	8	9
231	R:R:L36	R:R:Y40	2.34	No	Yes	0	5	7
232	R:R:Q227	R:R:Y226	2.25	No	No	0	4	3
233	L:L:G76	L:L:P75	2.03	No	Yes	0	8	9
234	R:R:G165	R:R:P167	2.03	No	No	0	7	7
235	R:R:C296	R:R:G47	1.96	Yes	No	0	8	8
236	R:R:C316	R:R:G56	1.96	No	No	0	4	4
237	R:R:G165	R:R:S114	1.86	No	No	0	7	5
238	R:R:G268	R:R:S267	1.86	No	No	0	1	3
239	R:R:G283	R:R:V286	1.84	No	No	0	5	5
240	R:R:G102	R:R:T101	1.82	No	Yes	0	7	7
241	R:R:C216	R:R:C217	1.82	No	No	0	3	4
242	R:R:A312	R:R:A57	1.79	No	No	0	6	7
243	R:R:P276	R:R:S267	1.78	Yes	No	0	2	3
244	R:R:G56	R:R:M55	1.75	No	No	0	4	7
245	R:R:G108	R:R:K107	1.74	No	No	0	5	7
246	R:R:C214	R:R:S128	1.72	No	No	0	8	9
247	R:R:G50	R:R:L49	1.71	No	No	0	7	4
248	R:R:C126	R:R:V153	1.71	No	No	0	7	5
249	R:R:C296	R:R:V297	1.71	Yes	No	0	8	7
250	L:L:V81	R:R:A264	1.7	Yes	No	0	9	4
251	R:R:C217	R:R:T213	1.69	No	No	0	4	4
252	R:R:L290	R:R:P256	1.64	No	No	0	7	9
253	R:R:A150	R:R:I70	1.62	No	No	0	8	6
254	R:R:A219	R:R:I240	1.62	No	No	0	5	6
255	R:R:S253	R:R:V252	1.62	No	No	0	8	5
256	R:R:A76	R:R:M55	1.61	No	No	0	8	7
257	R:R:A199	R:R:L164	1.58	No	No	0	5	4
258	R:R:A278	R:R:L282	1.58	No	No	0	1	1
259	R:R:A249	R:R:N294	1.56	No	No	0	7	9
260	R:R:I194	R:R:V198	1.54	No	No	0	4	3
261	R:R:I191	R:R:T189	1.52	No	No	0	4	3
262	R:R:A278	R:R:Q281	1.52	No	No	0	1	4
263	R:R:L123	R:R:S78	1.5	No	Yes	0	8	8
264	R:R:L170	R:R:S171	1.5	No	No	0	4	5
265	R:R:K192	R:R:T189	1.5	No	No	0	4	3
266	R:R:L222	R:R:S239	1.5	Yes	No	0	8	7
267	R:R:L208	R:R:V212	1.49	Yes	No	0	6	4
268	R:R:L263	R:R:V266	1.49	No	No	0	4	5
269	R:R:L36	R:R:T32	1.47	No	No	0	5	6
270	R:R:I157	R:R:I160	1.47	No	No	0	7	4
271	R:R:D306	R:R:S307	1.47	No	No	0	8	4
272	R:R:I245	R:R:K241	1.45	No	No	0	5	5
273	R:R:I218	R:R:L222	1.43	No	Yes	0	8	8
274	R:R:I240	R:R:L222	1.43	No	Yes	0	6	8
275	R:R:I243	R:R:L222	1.43	No	Yes	0	7	8
276	R:R:I265	R:R:L269	1.43	Yes	No	0	4	1
277	R:R:I313	R:R:L317	1.43	Yes	No	0	7	6
278	R:R:E285	R:R:T32	1.41	No	No	0	4	6
279	R:R:K107	R:R:L169	1.41	No	No	0	7	5
280	R:R:L208	R:R:L251	1.38	Yes	No	1	6	6
281	R:R:L208	R:R:L255	1.38	Yes	No	1	6	6
282	R:R:P138	R:R:W137	1.35	No	Yes	0	8	6
283	R:R:A199	R:R:W195	1.3	No	No	0	5	5
284	R:R:S267	R:R:Y274	1.27	No	No	0	3	6
285	R:R:V140	R:R:W137	1.23	No	Yes	0	5	6
286	R:R:F35	R:R:L36	1.22	No	No	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:V74	6.7	4	0	9
2	L:L:P75	5.56	4	0	9
3	L:L:L78	5.69	4	0	9
4	L:L:V81	3.905	4	0	9
5	R:R:Y40	6.39833	6	6	7
6	R:R:F44	7.4475	4	0	7
7	R:R:I68	3.395	4	0	8
8	R:R:F71	3.408	5	0	7
9	R:R:S78	4.39	4	7	8
10	R:R:F82	8.1125	4	0	6
11	R:R:E93	5.4625	4	0	4
12	R:R:W99	8.832	5	0	8
13	R:R:T101	4.814	5	3	7
14	R:R:Y111	6.402	5	0	6
15	R:R:Y132	6.602	5	9	8
16	R:R:W137	3.0125	4	9	6
17	R:R:R172	7.8275	4	2	5
18	R:R:P181	6.1825	4	4	4
19	R:R:C183	4.1175	4	2	9
20	R:R:F204	10.225	4	1	8
21	R:R:L208	1.98333	6	1	6
22	R:R:Y215	6.68	5	0	9
23	R:R:L222	1.4475	4	0	8
24	R:R:W254	5.97167	6	1	9
25	R:R:I265	3.675	4	0	4
26	R:R:P276	2.9325	4	0	2
27	R:R:F292	7.1575	4	6	7
28	R:R:C296	3.47	4	0	8
29	R:R:Y302	3.7375	4	0	9
30	R:R:F305	5.0225	4	0	6
31	R:R:I313	4.215	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:E68	L:L:P69	47.5213	3.14	No	No	0	2	3
2	L:L:P69	R:R:K186	49.156	3.35	No	No	0	3	3
3	L:L:W72	R:R:K186	55.5429	5.8	No	No	0	8	3
4	L:L:W72	R:R:T175	58.6527	8.49	No	No	0	8	2
5	R:R:P181	R:R:T175	59.6867	6.99	Yes	No	4	4	2
6	R:R:P181	R:R:Y182	64.4161	11.13	Yes	No	0	4	3
7	L:L:V74	R:R:Y182	65.8759	15.14	Yes	No	0	9	3
8	L:L:P75	L:L:V74	12.7661	3.53	Yes	Yes	0	9	9
9	L:L:V74	R:R:K92	66.2713	3.04	Yes	No	0	9	5
10	L:L:P75	R:R:R172	10.7132	7.21	Yes	Yes	0	9	5
11	R:R:K92	R:R:W89	68.5295	9.28	No	No	0	5	6
12	R:R:E93	R:R:W89	87.7737	3.27	Yes	No	0	4	6
13	R:R:E93	R:R:Y40	90.6402	6.73	Yes	Yes	0	4	7
14	R:R:F292	R:R:Y40	100	10.32	Yes	Yes	6	7	7
15	L:L:L78	R:R:F292	81.6302	4.87	Yes	Yes	0	9	7
16	R:R:R172	R:R:S110	13.8838	17.13	Yes	No	0	5	5
17	R:R:S110	R:R:T168	15.146	3.2	No	No	0	5	4
18	R:R:S114	R:R:T168	16.2941	9.59	No	No	0	5	4
19	L:L:P79	R:R:S114	29.0678	3.56	No	No	0	9	5
20	L:L:L78	R:R:M117	77.5395	5.65	Yes	No	0	9	7
21	L:L:L78	R:R:F257	31.2272	7.31	Yes	No	0	9	7
22	L:L:E68	R:R:K187	44.2062	12.15	No	No	0	2	4
23	R:R:A188	R:R:K187	14.743	3.21	No	No	5	4	4
24	R:R:A188	R:R:K192	12.9638	4.82	No	No	0	4	4
25	R:R:K187	R:R:L193	27.7752	2.82	No	No	5	4	2
26	R:R:I265	R:R:L193	26.2622	4.28	Yes	No	0	4	2
27	R:R:P289	R:R:Y40	19.5332	6.95	No	Yes	0	5	7
28	R:R:F39	R:R:P289	15.7999	2.89	No	No	0	5	5
29	R:R:F39	R:R:V43	11.945	7.87	No	No	0	5	7
30	R:R:L83	R:R:L86	11.8993	2.77	No	No	0	6	8
31	R:R:F292	R:R:F82	89.0283	8.57	Yes	Yes	0	7	6
32	R:R:F82	R:R:N116	43.1873	9.67	Yes	No	0	6	8
33	R:R:I81	R:R:N116	13.9903	9.91	No	No	0	7	8
34	R:R:I81	R:R:V84	12.0362	3.07	No	No	0	7	4
35	R:R:F80	R:R:V84	10.0669	3.93	No	No	0	7	4
36	R:R:F82	R:R:S295	66.0356	7.93	Yes	No	0	6	9
37	R:R:D79	R:R:S295	65.2068	8.83	No	No	0	9	9
38	R:R:D79	R:R:L75	63.6557	4.07	No	No	0	9	9
39	R:R:L75	R:R:N298	62.576	6.87	No	No	0	9	9
40	R:R:N298	R:R:Y302	62.059	5.81	No	Yes	0	9	9
41	R:R:I72	R:R:Y302	52.7448	3.63	No	Yes	0	8	9
42	R:R:I68	R:R:I72	51.5055	2.94	Yes	No	0	8	8
43	R:R:I68	R:R:R66	36.5116	3.76	Yes	No	0	8	7
44	R:R:R66	R:R:Y308	34.5575	14.4	No	No	0	7	6
45	R:R:K61	R:R:Y308	32.7099	10.75	No	No	0	5	6
46	R:R:A312	R:R:K61	28.9538	4.82	No	No	0	6	5
47	R:R:A312	R:R:A57	26.9617	1.79	No	No	0	6	7
48	R:R:A57	R:R:I313	24.9544	3.25	No	Yes	0	7	7
49	R:R:F71	R:R:I68	47.43	2.51	Yes	Yes	0	7	8
50	R:R:C154	R:R:F71	22.9243	2.79	No	Yes	0	7	7
51	R:R:C154	R:R:N74	20.8866	7.87	No	No	0	7	9
52	R:R:I73	R:R:N74	18.8336	2.83	No	No	0	6	9
53	R:R:D130	R:R:F71	12.5532	4.78	No	Yes	0	8	7
54	R:R:D130	R:R:L67	10.5839	6.79	No	No	0	8	5
55	R:R:M127	R:R:R131	29.1895	3.72	No	No	0	9	9
56	R:R:N116	R:R:S78	29.0754	5.96	No	Yes	0	8	8
57	R:R:W89	R:R:W99	24.8327	6.56	No	Yes	0	6	8
58	R:R:G165	R:R:S114	20.59	1.86	No	No	0	7	5
59	R:R:G165	R:R:Y111	16.1192	2.9	No	Yes	0	7	6
60	R:R:M117	R:R:W254	77.205	5.82	No	Yes	0	7	9
61	R:R:L123	R:R:S78	21.6545	1.5	No	Yes	0	8	8
62	R:R:I157	R:R:L123	19.7613	2.85	No	No	0	7	8
63	R:R:I157	R:R:L122	12.0362	7.14	No	No	0	7	5
64	R:R:L122	R:R:T203	10.0669	4.42	No	No	0	5	6
65	R:R:F204	R:R:W254	18.0505	3.01	Yes	Yes	1	8	9
66	R:R:F250	R:R:W254	61.2074	11.02	No	Yes	0	9	9
67	R:R:F250	R:R:I211	56.5998	3.77	No	No	0	9	8
68	R:R:I211	R:R:S128	52.8361	7.74	No	No	0	8	9
69	R:R:S128	R:R:Y215	38.055	10.17	No	Yes	0	9	9
70	R:R:C214	R:R:S128	24.9544	1.72	No	No	0	8	9
71	R:R:C214	R:R:Y132	23.2284	9.41	No	Yes	0	8	8
72	R:R:W137	R:R:Y132	11.6256	5.79	Yes	Yes	9	6	8
73	R:R:I265	R:R:L197	13.7241	2.85	Yes	No	0	4	4
74	R:R:F262	R:R:L197	11.8081	7.31	No	No	0	5	4
75	R:R:F204	R:R:L208	17.0316	2.44	Yes	Yes	1	8	6
76	R:R:F250	R:R:L208	22.5517	2.44	No	Yes	0	9	6
77	R:R:I243	R:R:Y215	10.1962	8.46	No	Yes	0	7	9
78	R:R:I313	R:R:Y303	18.8412	6.04	Yes	No	0	7	7
79	R:R:I304	R:R:Y303	16.7731	4.84	No	No	0	7	7
80	R:R:F305	R:R:I304	12.5912	8.79	Yes	No	0	6	7
81	R:R:L208	R:R:L255	22.2932	1.38	Yes	No	1	6	6
82	R:R:L255	R:R:P256	19.1986	3.28	No	No	0	6	9
83	R:R:P256	R:R:S287	12.8574	3.56	No	No	0	9	7
84	R:R:F257	R:R:M284	26.0873	4.98	No	No	0	7	4
85	R:R:L280	R:R:M284	23.7911	2.83	No	No	0	4	4
86	R:R:L280	R:R:P276	21.4796	3.28	No	Yes	0	4	2
87	R:R:P276	R:R:S267	14.4541	1.78	Yes	No	0	2	3
88	L:L:L78	L:L:P79	30.368	4.93	Yes	No	0	9	9
89	R:R:R131	R:R:Y215	34.5955	7.2	No	Yes	0	9	9
90	R:R:I68	R:R:M127	27.7676	4.37	Yes	No	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:E68	R:R:K187	12.15	0	No	No	2	4	0	1
L:L:P69	R:R:K186	3.35	0	No	No	3	3	0	1
L:L:W72	R:R:E173	7.63	0	No	No	8	4	0	1
L:L:W72	R:R:T175	8.49	0	No	No	8	2	0	1
L:L:W72	R:R:K186	5.8	0	No	No	8	3	0	1
L:L:V74	R:R:K92	3.04	0	Yes	No	9	5	0	1
L:L:V74	R:R:Y182	15.14	0	Yes	No	9	3	0	1
L:L:V74	R:R:A184	5.09	0	Yes	No	9	3	0	1
L:L:P75	R:R:R172	7.21	0	Yes	Yes	9	5	0	1
L:L:L78	R:R:M117	5.65	0	Yes	No	9	7	0	1
L:L:L78	R:R:F257	7.31	0	Yes	No	9	7	0	1
L:L:L78	R:R:F292	4.87	0	Yes	Yes	9	7	0	1
L:L:P79	R:R:S114	3.56	0	No	No	9	5	0	1
L:L:Q80	R:R:Q281	5.12	0	No	No	9	4	0	1
L:L:V81	R:R:K192	4.55	0	Yes	No	9	4	0	1
L:L:V81	R:R:S196	3.23	0	Yes	No	9	5	0	1
L:L:V81	R:R:I265	6.14	0	Yes	Yes	9	4	0	1
R:R:L86	R:R:Y40	9.38	6	No	Yes	8	7	2	1
R:R:E93	R:R:Y40	6.73	0	Yes	Yes	4	7	2	1
R:R:P289	R:R:Y40	6.95	0	No	Yes	5	7	2	1
R:R:F292	R:R:Y40	10.32	6	Yes	Yes	7	7	1	1
R:R:F292	R:R:F82	8.57	6	Yes	Yes	7	6	1	2
R:R:F292	R:R:L86	4.87	6	Yes	No	7	8	1	2
R:R:K92	R:R:W89	9.28	0	No	No	5	6	1	2
R:R:E93	R:R:W89	3.27	0	Yes	No	4	6	2	2
R:R:G97	R:R:K92	3.49	0	No	No	4	5	2	1
R:R:C106	R:R:R172	4.18	2	No	Yes	9	5	2	1
R:R:C106	R:R:C183	7.28	2	No	Yes	9	9	2	2
R:R:S110	R:R:T168	3.2	0	No	No	5	4	2	2
R:R:R172	R:R:S110	17.13	2	Yes	No	5	5	1	2
R:R:S114	R:R:T168	9.59	0	No	No	5	4	1	2
R:R:M117	R:R:W254	5.82	0	No	Yes	7	9	1	2
R:R:C183	R:R:R172	2.79	2	Yes	Yes	9	5	2	1
R:R:I177	R:R:T175	4.56	4	No	No	1	2	2	1
R:R:P181	R:R:T175	6.99	4	Yes	No	4	2	2	1
R:R:I177	R:R:P181	3.39	4	No	Yes	1	4	2	2
R:R:P181	R:R:Y182	11.13	4	Yes	No	4	3	2	1
R:R:E185	R:R:K186	10.8	0	No	No	5	3	2	1
R:R:A188	R:R:K187	3.21	5	No	No	4	4	2	1
R:R:K187	R:R:L193	2.82	5	No	No	4	2	1	2
R:R:A188	R:R:K192	4.82	5	No	No	4	4	2	1
R:R:A188	R:R:L193	3.15	5	No	No	4	2	2	2
R:R:I265	R:R:L193	4.28	0	Yes	No	4	2	1	2
R:R:I265	R:R:L197	2.85	0	Yes	No	4	4	1	2
R:R:F257	R:R:K261	3.72	0	No	No	7	5	1	2
R:R:F257	R:R:M284	4.98	0	No	No	7	4	1	2
L:L:A77	R:R:Y40	2.67	0	No	Yes	9	7	0	1
R:R:L36	R:R:Y40	2.34	0	No	Yes	5	7	2	1
R:R:G165	R:R:S114	1.86	0	No	No	7	5	2	1
L:L:V81	R:R:A264	1.7	0	Yes	No	9	4	0	1
R:R:A278	R:R:Q281	1.52	0	No	No	1	4	2	1
R:R:K192	R:R:T189	1.5	0	No	No	4	3	1	2
R:R:I265	R:R:L269	1.43	0	Yes	No	4	1	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9WXM_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.77
Number of Linked Nodes	268
Number of Links	286
Number of Hubs	31
Number of Links mediated by Hubs	124
Number of Communities	11
Number of Nodes involved in Communities	41
Number of Links involved in Communities	45

Path Summary
Number Of Nodes in MetaPath	91
Number Of Links MetaPath	90
Number of Shortest Paths	35675
Length Of Smallest Path	3
Average Path Length	14.8849
Length of Longest Path	41
Minimum Path Strength	1.29
Average Path Strength	5.91699
Maximum Path Strength	17.725
Minimum Path Correlation	0.7
Average Path Correlation	0.930156
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.85714
Average % Of Corr. Nodes	49.741
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	34.6062
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• regulation of biological process • regulation of cell motility • regulation of cellular process • regulation of leukocyte migration • biological regulation • lymphocyte migration • regulation of lymphocyte migration • leukocyte migration • immune system process • regulation of locomotion • regulation of T cell migration • mononuclear cell migration • regulation of cell migration • cell migration • cellular process • regulation of immune system process • T cell migration • cell motility • regulation of mononuclear cell migration • locomotion • establishment of organelle localization • multicellular organismal process • regulated exocytosis • cellular localization • response to stimulus • transport • cell activation involved in immune response • leukocyte degranulation • myeloid leukocyte activation • myeloid leukocyte mediated immunity • vesicle-mediated transport • leukocyte activation • localization • secretion by cell • organelle localization • leukocyte activation involved in immune response • establishment of localization in cell • mast cell activation • leukocyte mediated immunity • mast cell mediated immunity • immune response • secretion • cell activation • vacuolar localization • export from cell • mast cell degranulation • establishment of localization • myeloid cell activation involved in immune response • immune effector process • mast cell activation involved in immune response • exocytosis • lysosome localization • defense response to fungus • biological process involved in interspecies interaction between organisms • response to other organism • defense response • response to stress • response to external stimulus • response to fungus • response to external biotic stimulus • response to biotic stimulus • cell population proliferation • regulation of cell population proliferation • regulation of keratinocyte proliferation • regulation of epithelial cell proliferation • epithelial cell proliferation • keratinocyte proliferation • multicellular organismal-level homeostasis • leukocyte homeostasis • T cell homeostasis • homeostatic process • homeostasis of number of cells • lymphocyte homeostasis • cellular response to stimulus • signaling • G protein-coupled receptor signaling pathway • signal transduction • cell communication • cell chemotaxis • chemotaxis • lymphocyte chemotaxis • cellular response to chemical stimulus • taxis • response to chemical • leukocyte chemotaxis • regulation of cell cycle phase transition • regulation of cell cycle process • negative regulation of cell cycle G1/S phase transition • negative regulation of biological process • negative regulation of cell cycle • cell cycle phase transition • regulation of cell cycle G1/S phase transition • negative regulation of cell cycle process • cell cycle G1/S phase transition • negative regulation of cellular process • negative regulation of cell cycle phase transition • cell cycle • regulation of cell cycle • cell cycle process • negative regulation of cell division • cell division • regulation of cell division • defense response to Gram-positive bacterium • defense response to bacterium • response to bacterium • cellular anatomical structure • extracellular region • extracellular space • protein binding • binding • virus receptor activity • exogenous protein binding • molecular transducer activity • coreceptor activity • signaling receptor activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • developmental process • blood vessel morphogenesis • tube development • angiogenesis • vasculature development • circulatory system development • anatomical structure morphogenesis • multicellular organism development • tube morphogenesis • anatomical structure formation involved in morphogenesis • anatomical structure development • blood vessel development • system development • symbiont entry into host cell • viral process • symbiont entry into host • viral life cycle • biological process involved in interaction with host • biological process involved in symbiotic interaction • membrane-bounded organelle • intracellular anatomical structure • endosome • intracellular vesicle • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • cytoplasmic vesicle • organelle • cytoplasm • vesicle • cell periphery • plasma membrane • membrane • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • GDP binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • signaling receptor binding • G protein-coupled receptor binding • cation binding • metal ion binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • regulation of molecular function • regulation of adenylate cyclase activity • regulation of catalytic activity • negative regulation of molecular function • negative regulation of catalytic activity • negative regulation of adenylate cyclase activity • positive regulation of autophagy • catabolic process • macroautophagy • autophagy • positive regulation of biological process • regulation of catabolic process • regulation of autophagy • positive regulation of catabolic process • positive regulation of metabolic process • regulation of macroautophagy • metabolic process • positive regulation of macroautophagy • process utilizing autophagic mechanism • regulation of metabolic process • positive regulation of cellular process • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • nucleoside phosphate metabolic process • ribose phosphate metabolic process • purine nucleoside triphosphate metabolic process • GTP metabolic process • carbohydrate derivative metabolic process • primary metabolic process • nucleotide metabolic process • purine-containing compound metabolic process • nucleobase-containing compound metabolic process • purine nucleotide metabolic process • ribonucleotide metabolic process • organophosphate metabolic process • nucleobase-containing small molecule metabolic process • purine ribonucleoside triphosphate metabolic process • phosphate-containing compound metabolic process • small molecule metabolic process • nucleoside triphosphate metabolic process • purine ribonucleotide metabolic process • phosphorus metabolic process • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • cell projection • sperm principal piece • cilium • 9+2 motile cilium • sperm flagellum • motile cilium • plasma membrane bounded cell projection • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • ciliary basal body • enzyme binding • GTPase binding • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	L
Protein	GPR15L(CT)
UniProt	Q6UWK7
Sequence	>9WXM_nogp_Chain_L E P R L W V V P G A L P Q V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P49685
Sequence	>9WXM_nogp_Chain_R T S V F L P V F Y T A V F L T G V L G N L V L M G A L H F K P G S R R L I D I F I I N L A A S D F I F L V T L P L W V D K E A S L G L W R T G S F L C K G S S Y M I S V N M H C S V L L L T C M S V D R Y L A I V W P V V S R K F R R T D C A Y V V C A S I W F I S C L L G L P T L L S R E L T L I D D K P Y C A E K K A T P I K L I W S L V A L I F T F F V P L L S I V T C Y C C I A R K L C A H Y Q Q S G K H N K K L K K S I K I I F I V V A A F L V S W L P F N T F K F L A I V S G L R Q E H Y L P S A I L Q L G M E V S G P L A F A N S C V N P F I Y Y I F D S Y I R R A I V H C L C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7EWL	C	Orphan	Orphan	GPR158; GPR158	Homo sapiens	-	-	-	3.52	2021-12-01	doi.org/10.1038/s41467-021-27147-1
	7EWP	C	Orphan	Orphan	GPR158; GPR158	Homo sapiens	-	-	B5; RGS7	4.3	2021-12-01	doi.org/10.1038/s41467-021-27147-1
	7EWR	C	Orphan	Orphan	GPR158; GPR158	Homo sapiens	-	-	B5; RGS7	4.7	2021-12-01	doi.org/10.1038/s41467-021-27147-1
	7SHE	C	Orphan	Orphan	GPR158; GPR158	Homo sapiens	-	-	-	3.4	2021-12-01	doi.org/10.1126/science.abl4732
	7SHF	C	Orphan	Orphan	GPR158; GPR158	Homo sapiens	-	-	B5; RGS7	3.4	2021-12-01	doi.org/10.1126/science.abl4732
	8ZQE	A	Orphan	Orphan	GPR15	Homo sapiens	GPR15L(CT)	-	Gi1/β1/γ1	2.9	2024-07-10	doi.org/10.1038/s41421-024-00698-5
	8ZQE (No Gprot)	A	Orphan	Orphan	GPR15	Homo sapiens	GPR15L(CT)	-		2.9	2024-07-10	doi.org/10.1038/s41421-024-00698-5
	8IEB	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	PubChem 134746894	-	-	3.03	2024-02-14	doi.org/10.1038/s41594-024-01224-7
	8IED	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	PubChem 134746894	-	Go/β1/γ2	3.33	2024-02-14	doi.org/10.1038/s41594-024-01224-7
	8IED (No Gprot)	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	PubChem 134746894	-		3.33	2024-02-14	doi.org/10.1038/s41594-024-01224-7
	8IEI	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	PubChem 134746894	-	-	2.62	2024-02-14	doi.org/10.1038/s41594-024-01224-7
	8IEP	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	PubChem 134746894	-	-	2.61	2024-02-14	doi.org/10.1038/s41594-024-01224-7
	8YJP	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	-	-	-	3.09	2025-02-05	doi.org/10.1038/s41467-024-54681-5
	8YK0	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	-	-	Gi3/β1/γ2	2.4	2025-02-05	doi.org/10.1038/s41467-024-54681-5
	8YK0 (No Gprot)	C	Orphan	Orphan	GPR156; GPR156	Homo sapiens	-	-		2.4	2025-02-05	doi.org/10.1038/s41467-024-54681-5
	9WXM	A	Orphan	Orphan	GPR15	Homo sapiens	GPR15L(CT)	-	Gi3/β1/γ2	3.3	2025-11-19	10.1016/j.isci.2025.113935
	9WXM (No Gprot)	A	Orphan	Orphan	GPR15	Homo sapiens	GPR15L(CT)	-		3.3	2025-11-19	10.1016/j.isci.2025.113935
	9LHQ	B2	Orphan	Orphan	GPR155	Homo sapiens	-	-	-	3.46	2025-12-10	10.1016/j.scib.2025.09.012
	9LHV	B2	Orphan	Orphan	GPR155; GPR155	Homo sapiens	-	-	-	2.79	2025-12-10	10.1016/j.scib.2025.09.012
	9LHX	B2	Orphan	Orphan	GPR155; GPR155	Homo sapiens	-	-	-	5.62	2025-12-10	10.1016/j.scib.2025.09.012
	9VOR	C	Orphan	Orphan	GPR158; GPR158	Homo sapiens	-	-	-	3.47	2025-12-31	To be published

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Download 9WXM_nogp.zip

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