psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	NT.S568	NT.V577	3.23	No	No	0	9	3
2	NT.F569	NT.L572	4.265	Yes	No	1	9	9
3	1x43	NT.F569	7.135	No	Yes	0	9	9
4	1x47	NT.F569	4.87	No	Yes	0	8	9
5	2x64	NT.F569	3.75	Yes	Yes	1	9	9
6	7x45	NT.F569	3.02	Yes	Yes	1	9	9
7	7x38	NT.S570	9.765	No	No	0	8	9
8	NT.I571	NT.V577	3.075	Yes	No	0	7	3
9	2x64	NT.I571	3.765	Yes	Yes	1	9	7
10	E2.R729	NT.I571	5.635	No	Yes	1	5	7
11	E2.V732	NT.I571	3.84	No	Yes	1	4	7
12	2x64	NT.L572	3.65	Yes	No	1	9	9
13	3x40	NT.L572	7.62	Yes	No	0	8	9
14	5x40	NT.M573	4.565	Yes	Yes	0	7	9
15	6x56	NT.M573	5.24	No	Yes	1	9	9
16	6x59	NT.M573	3.015	Yes	Yes	1	7	9
17	7x41	NT.M573	6.22	Yes	Yes	1	9	9
18	NT.P575	NT.S574	3.56	No	No	0	6	9
19	6x59	NT.S574	4	Yes	No	0	7	9
20	6x63	NT.S574	3.26	No	No	0	5	9
21	E2.W737	NT.P575	16.215	Yes	No	0	6	6
22	6x63	NT.F576	5.945	No	No	0	5	3
23	1x32	1x35	3.385	No	Yes	0	4	4
24	1x32	7x38	5.34	No	No	0	4	8
25	1x35	1x38	3.07	Yes	No	0	4	3
26	1x35	1x39	3.84	Yes	No	0	4	8
27	1x36	1x37	4.33	No	No	0	1	1
28	1x36	1x40	22.335	No	No	0	1	3
29	1x42	7x43	4.995	No	No	0	9	5
30	1x46	7x47	5.27	No	No	0	9	7
31	1x47	2x61	4.75	No	No	0	8	7
32	1x49	7x47	4.395	No	No	0	7	7
33	1x50	7x50	3.71	No	No	0	9	9
34	1x51	2x58	4.28	No	No	0	7	8
35	1x53	7x54	6.005	No	No	0	8	8
36	1x54	2x57	4.845	Yes	Yes	0	9	9
37	1x54	2x58	5.535	Yes	No	0	9	8
38	1x54	7x50	3.42	Yes	No	0	9	9
39	1x55	2x58	3.565	No	No	0	5	8
40	1x56	7x54	4.15	No	No	0	6	8
41	1x58	2x55	4.15	No	No	0	8	5
42	1x61	1x65	3.27	Yes	No	0	9	9
43	1x61	2x47	7.56	Yes	Yes	0	9	9
44	1x64	8x53	4.875	Yes	No	0	8	7
45	I1.K616	I1x48	5.03	No	No	0	7	7
46	2x44	I1x48	3.275	No	No	0	6	7
47	2x44	I1x51	11.135	No	No	0	6	8
48	2x47	I1x51	4.95	Yes	No	0	9	8
49	2x41	I2.H692	3.09	No	No	0	7	6
50	2x41	4x39	3.84	No	No	0	7	6
51	2x42	3x57	16.175	No	Yes	0	8	8
52	2x45	3x53	5.16	No	No	2	7	7
53	2x45	Alloh345	3.935	No	Yes	2	7	0
54	2x46	2x47	5.86	No	Yes	0	9	9
55	2x46	2x50	4.96	No	No	0	9	7
56	2x48	4x43	3.645	No	No	0	7	7
57	2x48	Alloh345	4.41	No	Yes	0	7	0
58	2x49	3x50	3.17	No	No	0	7	8
59	2x49	Alloh345	3.51	No	Yes	0	7	0
60	2x50	6x48	7.775	No	No	0	7	6
61	2x52	3x46	22.035	No	Yes	3	9	9
62	2x52	4x47	6.04	No	Yes	3	9	8
63	2x53	3x47	4.375	No	No	0	8	9
64	2x56	3x42	4.89	No	No	0	8	8
65	2x56	3x43	3.75	No	No	0	8	7
66	2x57	2x61	7.465	Yes	No	0	9	7
67	2x57	3x43	4.845	Yes	No	0	9	7
68	2x59	3x39	13.815	No	No	0	7	8
69	2x60	3x40	6.67	No	Yes	0	9	8
70	2x61	3x40	4.025	No	Yes	0	7	8
71	2x63	2x66	3.065	No	No	0	6	8
72	2x63	3x32	3.24	No	No	0	6	7
73	2x63	3x35	17.04	No	No	0	6	8
74	2x70	3x28	4.81	No	No	0	5	5
75	E1.D648	E1.T650	5.06	No	No	0	5	3
76	3x26	3x30	3.2	No	No	0	4	6
77	3x29	E2.K728	5.655	No	No	0	9	5
78	3x29	E2x50	7.28	No	No	0	9	9
79	3x33	E2.Y727	5.68	No	Yes	0	8	9
80	3x34	3x35	6.43	No	No	0	8	8
81	3x34	4x57	5.285	No	No	0	8	9
82	3x36	3x40	3.125	No	Yes	0	7	8
83	3x36	E2x51	4.245	No	Yes	0	7	8
84	3x37	3x41	7.07	Yes	Yes	5	9	9
85	3x37	4x60	4.11	Yes	No	0	9	9
86	3x37	E2x52	3.86	Yes	Yes	0	9	9
87	3x37	5x39	7.355	Yes	Yes	5	9	8
88	3x38	3x39	5.895	Yes	No	0	7	8
89	3x38	4x54	6.7	Yes	No	0	7	7
90	3x38	4x57	6.605	Yes	No	0	7	9
91	3x40	5x39	3.095	Yes	Yes	0	8	8
92	3x41	4x53	3.28	Yes	Yes	0	9	9
93	3x41	5x39	3.045	Yes	Yes	5	9	8
94	3x41	5x42	3.28	Yes	No	0	9	9
95	3x42	4x53	3.56	No	Yes	0	8	9
96	3x43	3x47	3.535	No	No	0	7	9
97	3x44	5x39	3.75	No	Yes	0	9	8
98	3x44	5x43	4.855	No	No	0	9	9
99	3x44	6x53	17.54	No	Yes	0	9	9
100	3x45	4x49	3.655	Yes	No	0	8	6
101	3x45	4x52	4.89	Yes	No	0	8	8
102	3x45	4x53	10.835	Yes	Yes	0	8	9
103	3x45	5x46	3.14	Yes	No	0	8	9
104	3x46	4x47	5.515	Yes	Yes	3	9	8
105	3x46	4x491	4.22	Yes	No	0	9	9
106	3x46	4x50	7.72	Yes	No	3	9	9
107	3x47	6x50	3.49	No	No	0	9	9
108	3x48	5x46	5.71	No	No	0	7	9
109	3x49	4x46	4.365	No	No	2	6	7
110	3x49	4x49	5.65	No	No	0	6	6
111	3x49	Alloh345	9.28	No	Yes	2	6	0
112	3x52	Alloh345	11.07	No	Yes	0	8	0
113	3x53	3x57	5.465	No	Yes	2	7	8
114	3x53	Alloh345	5.29	No	Yes	2	7	0
115	3x55	5x53	3.39	No	No	0	6	8
116	3x56	3x57	5.145	Yes	Yes	2	8	8
117	3x56	3x60	6.445	Yes	No	2	8	6
118	3x56	I2.H691	3.265	Yes	No	2	8	7
119	3x56	I2.M693	6.585	Yes	No	2	8	5
120	3x56	4x42	4.19	Yes	No	2	8	8
121	3x57	4x42	3.72	Yes	No	2	8	8
122	3x58	5x60	5.09	No	No	0	7	8
123	3x59	5x56	5.71	No	No	0	6	7
124	3x59	Alloh345	5.22	No	Yes	0	6	0
125	3x60	I2.H691	3.86	No	No	2	6	7
126	3x60	Alloh345	6.805	No	Yes	2	6	0
127	I2.F690	I2.V689	5.9	No	No	0	8	9
128	I2.H691	I2.M693	4.595	No	No	2	7	5
129	4x39	4x40	3.71	No	No	0	6	5
130	4x42	Alloh345	5.405	No	Yes	2	8	0
131	4x43	4x47	3.11	No	Yes	0	7	8
132	4x46	Alloh345	4.565	No	Yes	2	7	0
133	4x47	4x50	3.09	Yes	No	3	8	9
134	4x61	4x65	3.43	No	No	4	7	7
135	4x61	E2.Y727	10.88	No	Yes	4	7	9
136	4x64	E2.Y727	4.995	No	Yes	0	9	9
137	4x64	5x35	6.995	No	No	0	9	8
138	4x65	E2.Y727	5.64	No	Yes	4	7	9
139	E2.Y727	E2x52	3.515	Yes	Yes	0	9	9
140	E2.R729	E2.V732	10.46	No	No	1	5	4
141	E2.R729	E2x51	4.5	No	Yes	0	5	8
142	E2x51	E2x52	11.39	Yes	Yes	0	8	9
143	5x39	E2x51	7.015	Yes	Yes	0	8	8
144	5x35	E2x52	4.925	No	Yes	0	8	9
145	5x36	E2x52	4.15	No	Yes	0	8	9
146	5x34	E2.W737	3.48	No	Yes	0	7	6
147	5x36	E2.W737	6.83	No	Yes	0	8	6
148	5x36	5x40	3.725	No	Yes	0	8	7
149	5x40	5x44	2.98	Yes	No	0	7	8
150	5x40	6x60	3.84	Yes	No	0	7	5
151	5x41	5x42	4.415	No	No	0	7	9
152	5x44	6x57	4.995	No	No	0	8	7
153	5x46	5x50	4.25	No	No	0	9	9
154	5x50	6x49	9.61	No	Yes	0	9	9
155	5x51	5x55	3.655	No	No	0	4	4
156	5x54	6x51	4.47	No	No	0	8	7
157	5x58	6x38	3.725	No	No	0	7	8
158	5x58	6x42	3.46	No	No	0	7	7
159	5x61	6x41	3	No	No	0	7	8
160	5x62	6x34	3.035	No	No	0	6	7
161	I3.R777	I3.T773	5.175	No	No	0	5	6
162	I3.R777	I3.V774	3.27	No	No	0	5	5
163	I3.R777	I3.R780	4.265	No	No	0	5	3
164	6x37	6x40	3.715	No	No	0	7	8
165	6x43	7x56	10.96	No	No	0	6	8
166	6x43	7x60	4.15	No	No	0	6	5
167	6x44	7x57	3.53	No	No	0	7	8
168	6x45	6x49	4.15	No	Yes	0	9	9
169	6x46	6x47	3.5	No	No	0	9	9
170	6x46	6x51	5.155	No	No	0	9	7
171	6x52	7x44	5.155	No	Yes	0	9	6
172	6x52	7x45	7.315	No	Yes	0	9	9
173	6x53	7x41	3.51	Yes	Yes	1	9	9
174	6x53	7x45	16.95	Yes	Yes	1	9	9
175	6x53	7x49	7.12	Yes	No	0	9	9
176	6x55	7x44	3.045	No	Yes	0	8	6
177	6x56	6x59	3.64	No	Yes	1	9	7
178	6x56	7x41	3.01	No	Yes	1	9	9
179	6x58	7x37	3.515	No	No	0	7	6
180	6x59	7x38	6.165	Yes	No	0	7	8
181	6x62	E3.Q815	3.92	No	No	0	4	3
182	6x62	7x34	7.405	No	No	6	4	5
183	6x62	7x37	3.35	No	No	6	4	6
184	7x34	7x37	11.3	No	No	6	5	6
185	7x41	7x45	13.29	Yes	Yes	1	9	9
186	7x47	7x51	6.435	No	No	0	7	5
187	7x51	7x52	5.895	No	No	0	5	7
188	7x51	7x55	6.98	No	No	0	5	7
189	7x55	7x56	3.495	No	No	0	7	8
190	7x59	8x55	3.045	No	No	0	7	3
191	8x47	8x49	5.53	No	Yes	7	9	8
192	8x47	8x50	6.105	No	No	7	9	8
193	8x48	8x51	7.25	No	No	0	5	7
194	8x49	8x50	3.525	Yes	No	7	8	8
195	1x34	7x35	3.685	No	No	0	3	2
196	1x57	1x61	3.04	No	Yes	0	7	9
197	1x61	2x50	3.385	Yes	No	0	9	7
198	1x64	2x47	3.205	Yes	Yes	0	8	9
199	E2.S741	E2.W737	3.09	No	Yes	0	8	6
200	5x35	E2.G740	3.045	No	No	0	8	4
201	6x34	6x37	7.76	No	No	0	7	7
202	6x42	6x46	2.95	No	No	0	7	9
203	1x60	7x58	2.94	No	No	0	8	7
204	2x41	3x57	2.92	No	Yes	0	7	8
205	E1.D648	E1.V651	2.92	No	No	0	5	1
206	3x38	4x53	2.89	Yes	Yes	0	7	9
207	6x47	7x52	2.89	No	No	0	9	7
208	5x63	I3.P772	2.88	No	No	0	8	7
209	1x35	7x35	2.855	Yes	No	0	4	2
210	1x60	8x54	2.855	No	No	0	8	7
211	3x58	5x56	2.855	No	No	0	7	7
212	6x40	7x60	2.82	No	No	0	8	5
213	7x43	7x44	2.77	No	Yes	0	5	6
214	5x47	6x54	2.76	No	No	0	8	6
215	8x51	8x55	2.67	No	No	0	7	3
216	1x52	1x55	2.645	No	No	0	3	5
217	6x57	6x58	2.645	No	No	0	7	7
218	E2.G740	E2.N736	2.545	No	No	0	4	8
219	3x29	E1.T649	2.535	No	No	0	9	3
220	6x36	6x37	2.505	No	No	0	4	7
221	7x44	7x52	2.44	Yes	No	0	6	7
222	2x40	2x42	2.4	No	No	0	8	8
223	E2.S724	E2.T726	2.4	No	No	0	3	4
224	1x57	7x54	2.38	No	No	0	7	8
225	1x58	2x54	2.365	No	No	0	8	8
226	7x34	7x36	2.345	No	No	0	5	6
227	3x58	5x57	2.305	No	No	0	7	9
228	3x33	E2.K728	2.28	No	No	0	8	5
229	3x30	E2.K728	2.25	No	No	0	6	5
230	5x58	6x41	2.25	No	No	0	7	8
231	3x48	5x49	2.235	No	No	0	7	7
232	3x54	5x57	2.235	No	No	0	9	9
233	2x51	2x52	2.22	No	No	0	7	9
234	E1.N652	E1.V651	2.215	No	No	0	4	1
235	3x28	E1.N652	2.215	No	No	0	5	4
236	6x31	I3.S779	2.21	No	No	0	7	4
237	1x55	1x59	2.205	No	No	0	5	6
238	E2.N736	E2.T726	2.195	No	No	0	8	4
239	E2.D731	E2.V732	2.19	No	No	0	3	4
240	8x49	I1x50	2.18	Yes	No	0	8	7
241	1x47	2x65	2.14	No	No	0	8	8
242	7x58	8x50	2.14	No	No	0	7	8
243	5x34	5x37	2.115	No	No	0	7	8
244	8x49	8x53	2.115	Yes	No	0	8	7
245	8x56	8x57	2.1	No	No	0	4	4
246	6x48	6x49	2.075	No	Yes	0	6	9
247	3x50	6x48	2.075	No	No	0	8	6
248	E2.N736	E2.N739	2.045	No	No	0	8	4
249	4x45	Alloh345	1.985	No	Yes	0	6	0
250	2x43	2x47	1.975	No	Yes	0	8	9
251	1x46	7x46	1.95	No	No	0	9	8
252	2x67	3x32	1.95	No	No	0	6	7
253	5x59	5x63	1.94	No	No	0	4	8
254	6x55	7x40	1.885	No	No	0	8	5
255	1x64	8x57	1.86	Yes	No	0	8	4
256	1x45	1x46	1.84	No	No	0	7	9
257	2x67	2x70	1.84	No	No	0	6	5
258	3x51	5x53	1.84	No	No	0	9	8
259	6x38	6x39	1.84	No	No	0	8	5
260	6x58	6x61	1.84	No	No	0	7	6
261	1x40	1x41	1.74	No	No	0	3	4
262	3x50	3x51	1.71	No	No	0	8	9
263	3x51	6x49	1.71	No	Yes	0	9	9
264	4x51	4x54	1.71	No	No	0	6	7
265	1x39	7x42	1.7	No	No	0	8	8
266	4x52	4x56	1.64	No	No	0	8	9
267	I3.E776	I3.G775	1.635	No	No	0	5	6
268	4x57	4x58	1.615	No	No	0	9	6
269	E2.S738	E2.T726	1.6	No	No	0	2	4
270	7x55	7x59	1.585	No	No	0	7	7
271	1x54	2x54	1.58	Yes	No	0	9	8
272	4x38	4x41	1.58	No	No	0	8	3
273	4x65	E2.P723	1.58	No	No	0	7	8
274	1x42	7x39	1.54	No	No	0	9	7
275	1x51	2x62	1.535	No	No	0	7	6
276	E1.T649	E2.K730	1.5	No	No	0	3	2
277	5x59	5x60	1.5	No	No	0	4	8
278	1x40	NT.T567	1.5	No	No	0	3	0
279	4x41	4x45	1.49	No	No	0	3	6
280	3x37	5x38	1.465	Yes	No	0	9	9
281	6x32	6x35	1.455	No	No	0	6	6
282	2x57	7x53	1.43	Yes	No	0	9	9
283	6x44	7x60	1.425	No	No	0	7	5
284	8x52	8x56	1.32	No	No	0	6	4
285	1x43	1x44	1.25	No	No	0	9	5
286	5x47	6x53	1.23	No	Yes	0	8	9
287	1x41	1x45	1.225	No	No	0	4	7
288	5x51	6x51	1.22	No	No	0	4	7
289	5x62	6x35	1.175	No	No	0	6	6
290	1x64	I1x49	1.17	Yes	No	0	8	5
291	3x27	3x30	0.91	No	No	0	3	6
292	2x68	NT.A567	0.895	No	No	0	7	9
293	1x48	1x51	0.88	No	No	0	5	7
294	E1.N652	E1.P653	0.815	No	No	0	4	4
295	4x63	4x64	0.795	No	No	0	5	9
296	1x62	1x63	0.79	No	No	0	5	4
297	4x58	4x59	0.77	No	No	0	6	7
298	6x30	6x33	0.77	No	No	0	6	6
299	4x59	4x63	0.77	No	No	0	7	5
300	2x64	2x68	0.695	Yes	No	0	9	7
301	6x31	6x32	0.69	No	No	0	7	6
302	1x33	1x36	0.66	No	No	0	3	1
303	1x63	1x64	0.61	No	Yes	0	4	8
304	I3.L778	I3.R780	0.605	No	No	0	5	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	NT.F569	4.608	5	1	9
2	NT.I571	4.07875	4	1	7
3	NT.M573	4.76	4	1	9
4	1x35	3.2875	4	0	4
5	1x54	3.845	4	0	9
6	1x61	4.31375	4	0	9
7	1x64	2.344	5	0	8
8	2x47	4.71	5	0	9
9	2x57	4.64625	4	0	9
10	2x64	2.965	4	1	9
11	3x37	4.772	5	5	9
12	3x38	5.5225	4	0	7
13	3x40	4.907	5	0	8
14	3x41	4.16875	4	5	9
15	3x45	5.63	4	0	8
16	3x46	9.8725	4	3	9
17	3x56	5.126	5	2	8
18	3x57	6.685	5	2	8
19	4x47	4.43875	4	3	8
20	4x53	5.14125	4	0	9
21	E2.Y727	6.142	5	4	9
22	E2x51	6.7875	4	0	8
23	E2x52	5.568	5	0	9
24	E2.W737	7.40375	4	0	6
25	5x39	4.852	5	5	8
26	5x40	3.7775	4	0	7
27	6x49	4.38625	4	0	9
28	6x53	9.27	5	1	9
29	6x59	4.205	4	1	7
30	7x41	6.5075	4	1	9
31	7x44	3.3525	4	0	6
32	7x45	10.1438	4	1	9
33	8x49	3.3375	4	7	8
34	Alloh345	5.58864	11	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	1x47	NT.F569	10.8078	4.87	No	Yes	0	8	9
2	7x45	NT.F569	15.5548	3.02	Yes	Yes	1	9	9
3	6x59	7x38	27.1102	6.165	Yes	No	0	7	8
4	6x59	NT.M573	20.8016	3.015	Yes	Yes	1	7	9
5	7x41	NT.M573	24.7213	6.22	Yes	Yes	1	9	9
6	7x41	7x45	23.0181	13.29	Yes	Yes	1	9	9
7	6x56	6x59	12.2677	3.64	No	Yes	1	9	7
8	6x56	7x41	13.2941	3.01	No	Yes	1	9	9
9	5x36	5x40	28.7206	3.725	No	Yes	0	8	7
10	5x36	E2x52	36.5909	4.15	No	Yes	0	8	9
11	E2x51	E2x52	19.3152	11.39	Yes	Yes	0	8	9
12	1x32	7x38	21.1467	5.34	No	No	0	4	8
13	1x32	1x35	18.1517	3.385	No	Yes	0	4	4
14	1x45	1x46	10.9405	1.84	No	No	0	7	9
15	1x46	7x47	14.0904	5.27	No	No	0	9	7
16	7x47	7x51	17.2049	6.435	No	No	0	7	5
17	7x51	7x52	44.439	5.895	No	No	0	5	7
18	7x44	7x52	60.6884	2.44	Yes	No	0	6	7
19	6x52	7x44	68.0676	5.155	No	Yes	0	9	6
20	6x52	7x45	69.2665	7.315	No	Yes	0	9	9
21	1x47	2x61	12.2368	4.75	No	No	0	8	7
22	2x61	3x40	16.5059	4.025	No	Yes	0	7	8
23	1x54	2x57	23.863	4.845	Yes	Yes	0	9	9
24	2x57	2x61	22.903	7.465	Yes	No	0	9	7
25	1x54	2x58	13.0331	5.535	Yes	No	0	9	8
26	1x61	2x50	30.5344	3.385	Yes	No	0	9	7
27	2x50	6x48	55.9414	7.775	No	No	0	7	6
28	6x48	6x49	47.934	2.075	No	Yes	0	6	9
29	5x50	6x49	52.2961	9.61	No	Yes	0	9	9
30	5x46	5x50	52.7827	4.25	No	No	0	9	9
31	3x45	5x46	55.4238	3.14	Yes	No	0	8	9
32	3x45	4x53	100	10.835	Yes	Yes	0	8	9
33	3x41	4x53	93.5985	3.28	Yes	Yes	0	9	9
34	3x41	5x39	60.7415	3.045	Yes	Yes	5	9	8
35	5x39	E2x51	17.0457	7.015	Yes	Yes	0	8	8
36	1x61	2x47	23.9869	7.56	Yes	Yes	0	9	9
37	2x46	2x47	23.3233	5.86	No	Yes	0	9	9
38	2x46	2x50	24.4514	4.96	No	No	0	9	7
39	1x64	2x47	34.0294	3.205	Yes	Yes	0	8	9
40	1x64	8x53	18.8064	4.875	Yes	No	0	8	7
41	2x41	3x57	10.0956	2.92	No	Yes	0	7	8
42	3x49	Alloh345	43.1517	9.28	No	Yes	2	6	0
43	3x49	4x49	44.6735	5.65	No	No	0	6	6
44	3x45	4x49	45.5981	3.655	Yes	No	0	8	6
45	4x42	Alloh345	11.7457	5.405	No	Yes	2	8	0
46	2x48	Alloh345	10.5955	4.41	No	Yes	0	7	0
47	2x49	Alloh345	13.5905	3.51	No	Yes	0	7	0
48	2x49	3x50	12.8252	3.17	No	No	0	7	8
49	3x50	6x48	12.2147	2.075	No	No	0	8	6
50	2x57	3x43	14.608	4.845	Yes	No	0	9	7
51	2x56	3x42	13.5861	4.89	No	No	0	8	8
52	3x42	4x53	14.7938	3.56	No	Yes	0	8	9
53	2x56	3x43	13.0508	3.75	No	No	0	8	7
54	3x38	4x53	25.0531	2.89	Yes	Yes	0	7	9
55	2x63	3x35	13.7144	17.04	No	No	0	6	8
56	3x34	3x35	15.0372	6.43	No	No	0	8	8
57	3x34	4x57	16.3511	5.285	No	No	0	8	9
58	3x38	4x57	18.8374	6.605	Yes	No	0	7	9
59	2x63	3x32	11.0423	3.24	No	No	0	6	7
60	3x33	E2.K728	15.8025	2.28	No	No	0	8	5
61	3x33	E2.Y727	17.8552	5.68	No	Yes	0	8	9
62	E2.Y727	E2x52	28.6763	3.515	Yes	Yes	0	9	9
63	3x37	E2x52	44.1913	3.86	Yes	Yes	0	9	9
64	3x37	5x39	12.8163	7.355	Yes	Yes	5	9	8
65	3x44	5x39	64.4443	3.75	No	Yes	0	9	8
66	6x53	7x45	45.7131	16.95	Yes	Yes	1	9	9
67	3x59	5x56	10.2283	5.71	No	No	0	6	7
68	3x59	Alloh345	11.2768	5.22	No	Yes	0	6	0
69	5x35	E2x52	17.581	4.925	No	Yes	0	8	9
70	5x40	5x44	14.4886	2.98	Yes	No	0	7	8
71	5x44	6x57	12.9136	4.995	No	No	0	8	7
72	6x46	6x47	16.6342	3.5	No	No	0	9	9
73	6x47	7x52	18.1782	2.89	No	No	0	9	7
74	6x37	6x40	11.5024	3.715	No	No	0	7	8
75	6x40	7x60	13.0641	2.82	No	No	0	8	5
76	6x43	7x60	17.7358	4.15	No	No	0	6	5
77	6x43	7x56	18.9436	10.96	No	No	0	6	8
78	7x55	7x56	20.4743	3.495	No	No	0	7	8
79	7x51	7x55	27.65	6.98	No	No	0	5	7
80	6x57	6x58	11.3299	2.645	No	No	0	7	7
81	8x49	8x53	16.7846	2.115	Yes	No	0	8	7
82	5x35	E2.G740	11.8784	3.045	No	No	0	8	4
83	5x40	NT.M573	21.3767	4.565	Yes	Yes	0	7	9
84	3x40	5x39	18.5675	3.095	Yes	Yes	0	8	8
85	3x44	6x53	63.2454	17.54	No	Yes	0	9	9
86	6x53	7x41	15.7937	3.51	Yes	Yes	1	9	9
87	3x37	3x41	33.2684	7.07	Yes	Yes	5	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x45	3x53	5.16	2	No	No	7	7	1	1
2x45	Alloh345	3.935	2	No	Yes	7	0	1	0
2x48	4x43	3.645	0	No	No	7	7	1	2
2x48	Alloh345	4.41	0	No	Yes	7	0	1	0
2x49	3x50	3.17	0	No	No	7	8	1	2
2x49	Alloh345	3.51	0	No	Yes	7	0	1	0
3x49	4x46	4.365	2	No	No	6	7	1	1
3x49	4x49	5.65	2	No	No	6	6	1	2
3x49	Alloh345	9.28	2	No	Yes	6	0	1	0
3x52	Alloh345	11.07	0	No	Yes	8	0	1	0
3x53	3x57	5.465	2	No	Yes	7	8	1	2
3x53	Alloh345	5.29	2	No	Yes	7	0	1	0
3x56	3x57	5.145	2	Yes	Yes	8	8	2	2
3x56	3x60	6.445	2	Yes	No	8	6	2	1
3x56	I2.H691	3.265	2	Yes	No	8	7	2	2
3x56	4x42	4.19	2	Yes	No	8	8	2	1
3x57	4x42	3.72	2	Yes	No	8	8	2	1
3x59	5x56	5.71	0	No	No	6	7	1	2
3x59	Alloh345	5.22	0	No	Yes	6	0	1	0
3x60	I2.H691	3.86	2	No	No	6	7	1	2
3x60	Alloh345	6.805	2	No	Yes	6	0	1	0
4x42	Alloh345	5.405	2	No	Yes	8	0	1	0
4x46	Alloh345	4.565	2	No	Yes	7	0	1	0
4x45	Alloh345	1.985	0	No	Yes	6	0	1	0
4x41	4x45	1.49	0	No	No	3	6	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
31.25	Single	7WU3	K6G	7WU3-ADGRF1-K6G-Gs/&β;1/&γ;2
25.00	Single	8G2Y	LPC	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2
23.08	Single	8U4N	Cholesterol	8U4N-CXCR4-Cholesterol-Gi1/&β;1/&γ;2
20.00	Single	7WU4	K6G	7WU4-ADGRF1-K6G-Gi1/&β;1/&γ;2
20.00	Single	8U4O	Cholesterol	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
20.00	Single	8U4R	Cholesterol	8U4R-CXCR4-REGN7663-Fab-Cholesterol
18.75	Single	8U4Q	Cholesterol	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
16.00	Single	5KW2	PubChem 133053953	5KW2-FFA1 (GPR40)-PubChem 133053953
13.33	Single	8U4P	Cholesterol	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
11.76	Single	7CKZ	Mevidalen	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
11.76	Single	7LJD	Mevidalen	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
11.76	Single	7X2F	Mevidalen	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
11.11	Single	7LJC	Mevidalen	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
11.11	Consensus	d1_on_allo	Other Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
10.53	Single	6N48	PubChem 138454256	6N48-β₂-BI167107-PubChem 138454256
9.52	Single	7WU5	K6G	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2
8.70	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
8.33	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
7.41	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
7.41	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
6.67	Single	5XSZ	Glyceryl Mono-oleate	5XSZ-LPA₆-Glyceryl Mono-oleate
6.25	Single	8T3O	2Y5	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	ffa4_on_allo	Other Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.88	Single	8WG8	Peptide	8WG8-Glucagon-Peptide-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	8G94	CD69	8G94-S1P₁-CD69-Gi1/&β;1/&γ;2
5.00	Single	5O9H	NDT9513727	5O9H-C5a₁-NDT9513727
4.00	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7

Consensus Members
	Id	Members
	7WU5	7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2
	8G2Y	8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2

Net Summary
I_min	2.965
Number of Linked Nodes	278
Number of Links	304
Number of Hubs	34
Number of Links mediated by Hubs	129
Number of Communities	7
Number of Nodes involved in Communities	39
Number of Links involved in Communities	50

Path Summary
Number Of Nodes in MetaPath	88
Number Of Links MetaPath	87
Number of Shortest Paths	52479
Length Of Smallest Path	3
Average Path Length	14.0949
Length of Longest Path	36
Minimum Path Strength	0.7
Average Path Strength	5.27024
Maximum Path Strength	17.245
Minimum Path Correlation	0.7
Average Path Correlation	0.918933
Maximum Path Correlation	0.995
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	42.9373
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.4684
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download adgrf1_on_allo.zip

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