psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:K39	8.96	Yes	No	0	0	8
2	L:L:?1	R:R:T109	5.2	Yes	No	1	0	5
3	L:L:?1	R:R:R124	6.86	Yes	Yes	1	0	6
4	L:L:?1	R:R:Q125	7.52	Yes	Yes	1	0	4
5	L:L:?1	R:R:D129	4.79	Yes	Yes	1	0	5
6	L:L:?1	R:R:Y202	4.96	Yes	Yes	1	0	4
7	L:L:?1	R:R:L207	3.91	Yes	No	1	0	6
8	L:L:?1	R:R:W210	8.04	Yes	No	0	0	6
9	L:L:?1	R:R:L278	6.84	Yes	No	1	0	6
10	L:L:?1	R:R:E293	23.38	Yes	No	0	0	4
11	L:L:?1	R:R:K294	5.97	Yes	No	1	0	4
12	L:L:?1	R:R:L297	16.61	Yes	No	0	0	6
13	R:R:F25	R:R:Q23	5.86	No	No	0	7	3
14	R:R:C190	R:R:C24	7.28	No	No	0	3	5
15	R:R:E28	R:R:N27	3.94	No	No	0	4	8
16	R:R:E28	R:R:F32	24.49	No	No	0	4	2
17	R:R:F32	R:R:F33	5.36	No	No	0	2	6
18	R:R:F33	R:R:I192	3.77	No	No	0	6	1
19	R:R:F33	R:R:L201	20.7	No	No	0	6	1
20	R:R:K39	R:R:Y34	8.36	No	Yes	0	8	6
21	R:R:L41	R:R:Y34	3.52	No	Yes	0	2	6
22	R:R:T113	R:R:Y34	7.49	No	Yes	0	5	6
23	R:R:P200	R:R:Y34	4.17	No	Yes	0	6	6
24	R:R:I192	R:R:R36	6.26	No	No	0	1	3
25	R:R:G38	R:R:S37	3.71	No	No	0	4	7
26	R:R:P200	R:R:S37	3.56	No	No	0	6	7
27	R:R:L41	R:R:R114	4.86	No	No	0	2	6
28	R:R:P111	R:R:W45	10.81	No	No	0	4	1
29	R:R:N46	R:R:S49	8.94	No	No	0	2	1
30	R:R:K294	R:R:V52	13.66	No	No	0	4	5
31	R:R:F103	R:R:I57	5.02	No	No	0	6	4
32	R:R:L298	R:R:V59	4.47	No	No	0	6	7
33	R:R:C60	R:R:Y102	4.03	No	Yes	0	6	7
34	R:R:C60	R:R:F103	6.98	No	No	0	6	6
35	R:R:I61	R:R:L65	4.28	No	No	0	4	4
36	R:R:G99	R:R:I63	5.29	No	No	0	7	8
37	R:R:F96	R:R:M64	11.2	No	No	0	7	6
38	R:R:L100	R:R:M64	5.65	No	No	0	4	6
39	R:R:A66	R:R:P308	3.74	No	No	0	8	9
40	R:R:A92	R:R:N67	4.69	No	Yes	0	9	9
41	R:R:D95	R:R:N67	5.39	Yes	Yes	0	9	9
42	R:R:F96	R:R:N67	3.62	No	Yes	0	7	9
43	R:R:N67	R:R:P308	6.52	Yes	No	0	9	9
44	R:R:L68	R:R:V72	5.96	No	No	0	4	5
45	R:R:A89	R:R:I74	6.5	No	No	0	7	7
46	R:R:F80	R:R:N77	8.46	Yes	No	4	8	6
47	R:R:N77	R:R:T321	7.31	No	No	4	6	7
48	R:R:H81	R:R:R78	5.64	No	No	0	8	6
49	R:R:F80	R:R:Y85	18.57	Yes	No	0	8	9
50	R:R:F80	R:R:M318	8.71	Yes	No	0	8	8
51	R:R:F80	R:R:T321	5.19	Yes	No	4	8	7
52	R:R:H81	R:R:Y86	9.8	No	No	0	8	4
53	R:R:F82	R:R:P83	4.33	No	No	0	7	6
54	R:R:M159	R:R:P83	8.39	No	No	0	6	6
55	R:R:P83	R:R:V164	5.3	No	Yes	0	6	7
56	R:R:I84	R:R:Y85	3.63	No	No	0	8	9
57	R:R:I84	R:R:M88	4.37	No	No	0	8	8
58	R:R:E145	R:R:I84	9.56	No	No	0	8	8
59	R:R:D315	R:R:Y85	5.75	No	No	0	8	9
60	R:R:N161	R:R:Y86	5.81	No	No	0	3	4
61	R:R:V164	R:R:Y86	3.79	Yes	No	0	7	4
62	R:R:E145	R:R:L87	6.63	No	No	0	8	8
63	R:R:M88	R:R:Y311	5.99	No	Yes	0	8	9
64	R:R:N138	R:R:N90	12.26	Yes	No	0	8	9
65	R:R:I168	R:R:N90	8.5	No	No	0	8	9
66	R:R:N90	R:R:W172	6.78	No	No	0	9	9
67	R:R:D95	R:R:L91	5.43	Yes	Yes	0	9	9
68	R:R:L91	R:R:N138	6.87	Yes	Yes	0	9	8
69	R:R:L139	R:R:L91	4.15	No	Yes	2	8	9
70	R:R:I142	R:R:L91	4.28	No	Yes	2	8	9
71	R:R:L91	R:R:Y311	3.52	Yes	Yes	2	9	9
72	R:R:D95	R:R:S304	5.89	Yes	No	0	9	9
73	R:R:D95	R:R:N307	8.08	Yes	No	0	9	9
74	R:R:F97	R:R:T130	3.89	No	No	0	7	6
75	R:R:F97	R:R:W172	4.01	No	No	0	7	9
76	R:R:L105	R:R:Y102	3.52	No	Yes	0	6	7
77	R:R:M106	R:R:Y102	7.18	No	Yes	0	6	7
78	R:R:L297	R:R:Y102	5.86	No	Yes	0	6	7
79	R:R:L298	R:R:Y102	7.03	No	Yes	0	6	7
80	R:R:E301	R:R:Y102	25.81	No	Yes	0	7	7
81	R:R:F103	R:R:F107	6.43	No	No	0	6	5
82	R:R:N108	R:R:Y104	9.3	No	No	0	5	5
83	R:R:L123	R:R:Y104	3.52	No	No	0	4	5
84	R:R:L105	R:R:R124	6.07	No	Yes	0	6	6
85	R:R:I128	R:R:L105	4.28	No	No	0	6	6
86	R:R:N108	R:R:R124	8.44	No	Yes	0	5	6
87	R:R:K294	R:R:T109	4.5	No	No	1	4	5
88	R:R:G110	R:R:P111	4.06	No	No	0	5	4
89	R:R:R124	R:R:T113	3.88	Yes	No	0	6	5
90	R:R:L116	R:R:R124	4.86	No	Yes	0	6	6
91	R:R:R124	R:R:W121	7	Yes	Yes	1	6	9
92	R:R:Q125	R:R:W121	15.33	Yes	Yes	1	4	9
93	R:R:P200	R:R:W121	5.4	No	Yes	0	6	9
94	R:R:L201	R:R:W121	10.25	No	Yes	0	1	9
95	R:R:L122	R:R:Y202	3.52	No	Yes	0	5	4
96	R:R:Q125	R:R:R124	9.35	Yes	Yes	1	4	6
97	R:R:Q125	R:R:Y202	6.76	Yes	Yes	1	4	4
98	R:R:D129	R:R:Y202	8.05	Yes	Yes	1	5	4
99	R:R:D129	R:R:Y206	8.05	Yes	Yes	1	5	7
100	R:R:L132	R:R:W271	6.83	No	Yes	0	7	8
101	R:R:E301	R:R:L132	6.63	No	No	0	7	7
102	R:R:M178	R:R:T133	4.52	No	No	0	5	6
103	R:R:T133	R:R:W210	6.06	No	No	0	6	6
104	R:R:A134	R:R:W172	3.89	No	No	0	7	9
105	R:R:N214	R:R:V136	5.91	Yes	Yes	3	7	8
106	R:R:T217	R:R:V136	4.76	No	Yes	0	7	8
107	R:R:F267	R:R:V136	5.24	Yes	Yes	3	9	8
108	R:R:V136	R:R:W271	4.9	Yes	Yes	3	8	8
109	R:R:A137	R:R:I171	4.87	No	No	0	5	7
110	R:R:I171	R:R:N138	9.91	No	Yes	0	7	8
111	R:R:L139	R:R:N307	8.24	No	No	0	8	9
112	R:R:L139	R:R:Y311	3.52	No	Yes	2	8	9
113	R:R:I144	R:R:L140	7.14	No	No	0	6	7
114	R:R:L140	R:R:T217	5.9	No	No	0	7	7
115	R:R:I142	R:R:R146	3.76	No	No	2	8	9
116	R:R:I142	R:R:Y311	4.84	No	Yes	2	8	9
117	R:R:A143	R:R:Y225	4	No	Yes	0	8	9
118	R:R:R146	R:R:Y225	8.23	No	Yes	0	9	9
119	R:R:R146	R:R:Y311	6.17	No	Yes	2	9	9
120	R:R:F151	R:R:H147	15.84	Yes	Yes	5	6	7
121	R:R:H147	R:R:L224	7.71	Yes	No	0	7	6
122	R:R:H147	R:R:H227	9.55	Yes	No	5	7	5
123	R:R:H147	R:R:I228	3.98	Yes	No	0	7	9
124	R:R:R152	R:R:T149	7.76	No	No	0	5	8
125	R:R:F151	R:R:V150	3.93	Yes	No	0	6	8
126	R:R:F151	R:R:H227	13.58	Yes	No	5	6	5
127	R:R:F151	R:R:Y231	13.41	Yes	No	0	6	6
128	R:R:R152	R:R:T157	10.35	No	No	0	5	4
129	R:R:Q154	R:R:T157	12.76	No	No	0	4	4
130	R:R:H156	R:R:L155	7.71	No	No	0	4	8
131	R:R:F213	R:R:M174	4.98	No	No	0	5	4
132	R:R:M178	R:R:Y206	3.59	No	Yes	0	5	7
133	R:R:F209	R:R:M178	4.98	No	No	0	6	5
134	R:R:P182	R:R:Y202	13.91	No	Yes	1	6	4
135	R:R:P182	R:R:Y206	19.47	No	Yes	1	6	7
136	R:R:G185	R:R:V184	3.68	No	No	0	5	5
137	R:R:S205	R:R:W186	8.65	No	No	0	5	6
138	R:R:W186	R:R:Y206	3.86	No	Yes	0	6	7
139	R:R:I189	R:R:N187	8.5	Yes	No	0	3	6
140	R:R:C188	R:R:C195	7.28	No	No	0	5	9
141	R:R:I189	R:R:L201	4.28	Yes	No	0	3	1
142	R:R:D191	R:R:N194	4.04	No	No	0	4	3
143	R:R:D281	R:R:S196	4.42	Yes	No	0	4	5
144	R:R:D281	R:R:N197	12.12	Yes	No	0	4	5
145	R:R:L277	R:R:M198	5.65	No	No	0	4	3
146	R:R:D281	R:R:M198	9.7	Yes	No	0	4	3
147	R:R:E293	R:R:M198	14.89	No	No	0	4	3
148	R:R:A199	R:R:Y202	4	No	Yes	0	4	4
149	R:R:Y202	R:R:Y206	8.94	Yes	Yes	1	4	7
150	R:R:S203	R:R:S205	4.89	No	No	0	5	5
151	R:R:D204	R:R:V282	8.76	No	Yes	0	4	5
152	R:R:L207	R:R:L278	5.54	No	No	1	6	6
153	R:R:W210	R:R:W271	4.69	No	Yes	0	6	8
154	R:R:F213	R:R:T217	5.19	No	No	0	5	7
155	R:R:F267	R:R:N214	7.25	Yes	Yes	3	9	7
156	R:R:N214	R:R:W271	11.3	Yes	Yes	3	7	8
157	R:R:L275	R:R:N214	12.36	No	Yes	0	6	7
158	R:R:F218	R:R:V222	7.87	No	No	0	5	4
159	R:R:F218	R:R:F267	11.79	No	Yes	0	5	9
160	R:R:F218	R:R:I268	5.02	No	No	0	5	6
161	R:R:F267	R:R:M221	3.73	Yes	No	0	9	9
162	R:R:V260	R:R:Y225	5.05	No	Yes	0	8	9
163	R:R:V263	R:R:Y225	5.05	No	Yes	0	8	9
164	R:R:F229	R:R:L256	8.53	No	No	0	6	7
165	R:R:F229	R:R:L257	7.31	No	No	0	6	7
166	R:R:R235	R:R:Y231	10.29	No	No	0	7	6
167	R:R:L256	R:R:V232	4.47	No	No	0	7	7
168	R:R:D251	R:R:M253	4.16	No	No	0	5	7
169	R:R:K258	R:R:M254	8.64	No	No	0	7	5
170	R:R:R314	R:R:S255	9.22	No	No	0	7	7
171	R:R:T259	R:R:Y313	4.99	No	No	6	8	5
172	R:R:R314	R:R:T259	11.64	No	No	6	7	8
173	R:R:I262	R:R:Y313	7.25	No	No	0	6	5
174	R:R:V263	R:R:Y311	6.31	No	Yes	0	8	9
175	R:R:F267	R:R:W271	17.04	Yes	Yes	3	9	8
176	R:R:I268	R:R:T272	6.08	No	No	0	6	5
177	R:R:C270	R:R:N303	9.45	No	No	0	9	9
178	R:R:A300	R:R:W271	5.19	No	Yes	0	7	8
179	R:R:N303	R:R:W271	7.91	No	Yes	0	9	8
180	R:R:P273	R:R:T272	5.25	Yes	No	0	9	5
181	R:R:F296	R:R:P273	8.67	Yes	Yes	0	5	9
182	R:R:F296	R:R:L277	7.31	Yes	No	0	5	4
183	R:R:C287	R:R:L280	4.76	No	No	0	5	5
184	R:R:L280	R:R:V289	4.47	No	No	0	5	4
185	R:R:D281	R:R:V289	4.38	Yes	No	0	4	4
186	R:R:C284	R:R:P285	3.77	No	No	0	4	3
187	R:R:C284	R:R:C287	7.28	No	No	0	4	5
188	R:R:F302	R:R:M306	13.68	No	No	0	5	6
189	R:R:N303	R:R:N307	6.81	No	No	0	9	9
190	R:R:I310	R:R:Y311	3.63	No	Yes	0	8	9
191	R:R:M318	R:R:S312	6.13	No	No	0	8	7
192	R:R:R314	R:R:Y313	17.49	No	No	6	7	5
193	R:R:A320	R:R:K316	4.82	No	No	0	4	5
194	R:R:F322	R:R:M318	4.98	No	No	0	6	8
195	R:R:G54	R:R:M53	3.49	No	No	0	4	4
196	R:R:A98	R:R:S131	3.42	No	No	0	8	6
197	R:R:A98	R:R:S304	3.42	No	No	0	8	9
198	R:R:A101	R:R:S131	3.42	No	No	0	5	6
199	R:R:A92	R:R:V70	3.39	No	No	0	9	9
200	R:R:I181	R:R:P182	3.39	No	No	0	5	6
201	R:R:A175	R:R:T133	3.36	No	No	0	8	6
202	R:R:D129	R:R:G126	3.35	Yes	No	0	5	6
203	R:R:L299	R:R:P273	3.28	No	Yes	0	7	9
204	R:R:H81	R:R:Y75	3.27	No	No	0	8	3
205	R:R:A305	R:R:I63	3.25	No	No	0	7	8
206	R:R:A141	R:R:I171	3.25	No	No	0	8	7
207	R:R:V208	R:R:V282	3.21	No	Yes	0	4	5
208	R:R:S119	R:R:T117	3.2	No	No	0	1	6
209	R:R:S119	R:R:T120	3.2	No	No	0	1	4
210	R:R:A94	R:R:N138	3.13	No	Yes	0	8	8
211	R:R:I63	R:R:S304	3.1	No	No	0	8	9
212	R:R:F296	R:R:Y292	3.09	Yes	No	0	5	3
213	R:R:I74	R:R:V70	3.07	No	No	0	7	9
214	R:R:M159	R:R:S160	3.07	No	No	0	6	8
215	R:R:I168	R:R:V164	3.07	No	Yes	0	8	7
216	R:R:I181	R:R:V177	3.07	No	No	0	5	4
217	R:R:I212	R:R:V208	3.07	No	No	0	4	4
218	R:R:I176	R:R:T130	3.04	No	No	0	3	6
219	R:R:M253	R:R:T252	3.01	No	No	0	7	5
220	R:R:L87	R:R:V167	2.98	No	No	0	8	6
221	R:R:L140	R:R:V220	2.98	No	No	0	7	5
222	R:R:L207	R:R:V282	2.98	No	Yes	0	6	5
223	R:R:L224	R:R:V220	2.98	No	No	0	6	5
224	R:R:L264	R:R:V222	2.98	No	No	0	7	4
225	R:R:L257	R:R:V261	2.98	No	No	0	7	5
226	R:R:N46	R:R:V48	2.96	No	No	0	2	3
227	R:R:N77	R:R:V76	2.96	No	No	0	6	5
228	R:R:L41	R:R:T43	2.95	No	No	0	2	3
229	R:R:L116	R:R:T120	2.95	No	No	0	6	4
230	R:R:D95	R:R:S135	2.94	Yes	No	0	9	9
231	R:R:I262	R:R:I310	2.94	No	No	0	6	8
232	R:R:A42	R:R:H40	2.93	No	No	0	4	2
233	R:R:I30	R:R:L116	2.85	No	No	0	6	6
234	R:R:L298	R:R:L55	2.77	No	No	0	6	4
235	R:R:A305	R:R:F62	2.77	No	No	0	7	4
236	R:R:A73	R:R:F322	2.77	No	No	0	7	6
237	R:R:A305	R:R:F302	2.77	No	No	0	7	5
238	R:R:D288	R:R:L290	2.71	No	No	0	1	3
239	R:R:A291	R:R:Y292	2.67	No	No	0	2	3
240	R:R:E193	R:R:N194	2.63	No	No	0	4	3
241	R:R:M253	R:R:R233	2.48	No	No	0	7	5
242	R:R:F97	R:R:L127	2.44	No	No	0	7	5
243	R:R:F25	R:R:N27	2.42	No	No	0	7	8
244	R:R:M153	R:R:Y231	2.39	No	No	0	7	6
245	R:R:G274	R:R:P273	2.03	No	Yes	0	5	9
246	R:R:G56	R:R:V59	1.84	No	No	0	6	7
247	R:R:G110	R:R:T109	1.82	No	No	0	5	5
248	R:R:G179	R:R:T130	1.82	No	No	0	7	6
249	R:R:G54	R:R:I57	1.76	No	No	0	4	4
250	R:R:G265	R:R:I268	1.76	No	No	0	4	6
251	R:R:C195	R:R:S203	1.72	No	No	0	9	5
252	R:R:A31	R:R:S29	1.71	No	No	0	2	4
253	R:R:C283	R:R:V282	1.71	No	Yes	0	4	5
254	R:R:C24	R:R:I189	1.64	No	Yes	0	5	3
255	R:R:C270	R:R:I269	1.64	No	No	0	9	5
256	R:R:A266	R:R:M306	1.61	No	No	0	6	6
257	R:R:V150	R:R:V232	1.6	No	No	0	8	7
258	R:R:V164	R:R:V165	1.6	Yes	No	0	7	1
259	R:R:V216	R:R:V219	1.6	No	No	0	4	3
260	R:R:T47	R:R:V48	1.59	No	No	0	5	3
261	R:R:T236	R:R:V232	1.59	No	No	0	5	7
262	R:R:T272	R:R:V276	1.59	No	No	0	5	6
263	R:R:C283	R:R:L279	1.59	No	No	0	4	6
264	R:R:A211	R:R:L275	1.58	No	No	0	4	6
265	R:R:A211	R:R:L279	1.58	No	No	0	4	6
266	R:R:T236	R:R:T252	1.57	No	No	0	5	5
267	R:R:A42	R:R:N46	1.56	No	No	0	4	2
268	R:R:I189	R:R:V118	1.54	Yes	No	0	3	2
269	R:R:I212	R:R:V216	1.54	No	No	0	4	4
270	R:R:A291	R:R:D288	1.54	No	No	0	2	1
271	R:R:M254	R:R:S255	1.53	No	No	0	5	7
272	R:R:I57	R:R:T58	1.52	No	No	0	4	5
273	R:R:M174	R:R:V170	1.52	No	No	0	4	3
274	R:R:F229	R:R:G230	1.51	No	No	0	6	2
275	R:R:E145	R:R:T149	1.41	No	No	0	8	8
276	R:R:L51	R:R:L55	1.38	No	No	0	4	4
277	R:R:L65	R:R:L69	1.38	No	No	0	4	7
278	R:R:R162	R:R:S160	1.32	No	No	0	5	8
279	R:R:F295	R:R:V48	1.31	No	No	0	4	3
280	R:R:R162	R:R:V166	1.31	No	No	0	5	3
281	R:R:F62	R:R:I61	1.26	No	No	0	4	4
282	R:R:E317	R:R:F80	1.17	No	Yes	0	7	8
283	R:R:N35	R:R:Y34	1.16	No	Yes	0	7	6
284	R:R:K50	R:R:W45	1.16	No	No	0	3	1
285	R:R:F80	R:R:R79	1.07	Yes	No	0	8	6
286	R:R:R162	R:R:R163	1.07	No	No	0	5	6
287	R:R:F295	R:R:F296	1.07	No	Yes	0	4	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	8.58667	12	1	0
2	R:R:Y34	4.94	5	0	6
3	R:R:N67	5.055	4	0	9
4	R:R:F80	7.195	6	4	8
5	R:R:L91	4.85	5	2	9
6	R:R:D95	5.546	5	0	9
7	R:R:Y102	8.905	6	0	7
8	R:R:W121	9.495	4	1	9
9	R:R:R124	6.63714	7	1	6
10	R:R:Q125	9.74	4	1	4
11	R:R:D129	6.06	4	1	5
12	R:R:V136	5.2025	4	3	8
13	R:R:N138	8.0425	4	0	8
14	R:R:H147	9.27	4	5	7
15	R:R:F151	11.69	4	5	6
16	R:R:V164	3.44	4	0	7
17	R:R:I189	3.99	4	0	3
18	R:R:Y202	7.16286	7	1	4
19	R:R:Y206	8.782	5	1	7
20	R:R:N214	9.205	4	3	7
21	R:R:Y225	5.5825	4	0	9
22	R:R:F267	9.01	5	3	9
23	R:R:W271	8.26571	7	3	8
24	R:R:P273	4.8075	4	0	9
25	R:R:D281	7.655	4	0	4
26	R:R:V282	4.165	4	0	5
27	R:R:F296	5.035	4	0	5
28	R:R:Y311	4.85429	7	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:R124	25.9493	6.86	Yes	Yes	1	0	6
2	R:R:R124	R:R:W121	17.0562	7	Yes	Yes	1	6	9
3	R:R:L201	R:R:W121	26.4913	10.25	No	Yes	0	1	9
4	R:R:F33	R:R:L201	15.4153	20.7	No	No	0	6	1
5	L:L:?1	R:R:Q125	15.9046	7.52	Yes	Yes	1	0	4
6	R:R:Q125	R:R:W121	16.2094	15.33	Yes	Yes	1	4	9
7	L:L:?1	R:R:E293	25.2794	23.38	Yes	No	0	0	4
8	R:R:E293	R:R:M198	24.2821	14.89	No	No	0	4	3
9	R:R:L277	R:R:M198	15.3325	5.65	No	No	0	4	3
10	R:R:F296	R:R:L277	14.3051	7.31	Yes	No	0	5	4
11	R:R:F295	R:R:F296	11.5464	1.07	No	Yes	0	4	5
12	L:L:?1	R:R:W210	75.8872	8.04	Yes	No	0	0	6
13	R:R:W210	R:R:W271	81.2239	4.69	No	Yes	0	6	8
14	R:R:N303	R:R:W271	100	7.91	No	Yes	0	9	8
15	R:R:N303	R:R:N307	99.0968	6.81	No	No	0	9	9
16	R:R:D95	R:R:N307	44.4018	8.08	Yes	No	0	9	9
17	R:R:D95	R:R:S304	15.6449	5.89	Yes	No	0	9	9
18	R:R:I63	R:R:S304	11.3244	3.1	No	No	0	8	9
19	R:R:D95	R:R:N67	11.3244	5.39	Yes	Yes	0	9	9
20	R:R:L139	R:R:N307	54.5708	8.24	No	No	0	8	9
21	R:R:L139	R:R:Y311	30.0478	3.52	No	Yes	2	8	9
22	R:R:M88	R:R:Y311	21.8095	5.99	No	Yes	0	8	9
23	R:R:I84	R:R:M88	20.8122	4.37	No	No	0	8	8
24	R:R:I84	R:R:Y85	12.8561	3.63	No	No	0	8	9
25	R:R:F80	R:R:Y85	10.7185	18.57	Yes	No	0	8	9
26	R:R:D95	R:R:L91	30.8005	5.43	Yes	Yes	0	9	9
27	R:R:L91	R:R:N138	51.7067	6.87	Yes	Yes	0	9	8
28	R:R:N138	R:R:N90	42.8625	12.26	Yes	No	0	8	9
29	R:R:I168	R:R:N90	28.3203	8.5	No	No	0	8	9
30	R:R:I168	R:R:V164	26.4687	3.07	No	Yes	0	8	7
31	R:R:L139	R:R:L91	23.9396	4.15	No	Yes	2	8	9
32	R:R:P83	R:R:V164	13.2965	5.3	No	Yes	0	6	7
33	R:R:N90	R:R:W172	13.5373	6.78	No	No	0	9	9
34	R:R:E301	R:R:Y102	10.8916	25.81	No	Yes	0	7	7
35	L:L:?1	R:R:Y202	11.7007	4.96	Yes	Yes	1	0	4
36	R:R:L132	R:R:W271	12.1486	6.83	No	Yes	0	7	8
37	R:R:V136	R:R:W271	27.6279	4.9	Yes	Yes	3	8	8
38	R:R:T217	R:R:V136	29.6526	4.76	No	Yes	0	7	8
39	R:R:F267	R:R:W271	16.3938	17.04	Yes	Yes	3	9	8
40	R:R:L140	R:R:T217	25.5278	5.9	No	No	0	7	7
41	R:R:L140	R:R:V220	23.4203	2.98	No	No	0	7	5
42	R:R:L224	R:R:V220	22.3552	2.98	No	No	0	6	5
43	R:R:H147	R:R:L224	21.2826	7.71	Yes	No	0	7	6
44	R:R:F151	R:R:H147	18.0573	15.84	Yes	Yes	5	6	7
45	R:R:F151	R:R:V150	13.7594	3.93	Yes	No	0	6	8
46	R:R:W186	R:R:Y206	13.6954	3.86	No	Yes	0	6	7
47	R:R:S205	R:R:W186	10.9706	8.65	No	No	0	5	6
48	R:R:F218	R:R:F267	17.1691	11.79	No	Yes	0	5	9
49	R:R:F218	R:R:I268	14.0981	5.02	No	No	0	5	6
50	R:R:V150	R:R:V232	12.619	1.6	No	No	0	8	7
51	R:R:I268	R:R:T272	12.0884	6.08	No	No	0	6	5
52	R:R:F296	R:R:P273	10.3421	8.67	Yes	Yes	0	5	9
53	R:R:P273	R:R:T272	10.7711	5.25	Yes	No	0	9	5
54	R:R:E301	R:R:L132	11.1324	6.63	No	No	0	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:K39	8.96	1	Yes	No	0	8	0	1
L:L:?1	R:R:T109	5.2	1	Yes	No	0	5	0	1
L:L:?1	R:R:R124	6.86	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:Q125	7.52	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:D129	4.79	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:Y202	4.96	1	Yes	Yes	0	4	0	1
L:L:?1	R:R:L207	3.91	1	Yes	No	0	6	0	1
L:L:?1	R:R:W210	8.04	1	Yes	No	0	6	0	1
L:L:?1	R:R:L278	6.84	1	Yes	No	0	6	0	1
L:L:?1	R:R:E293	23.38	1	Yes	No	0	4	0	1
L:L:?1	R:R:K294	5.97	1	Yes	No	0	4	0	1
L:L:?1	R:R:L297	16.61	1	Yes	No	0	6	0	1
R:R:K39	R:R:Y34	8.36	0	No	Yes	8	6	1	2
R:R:T113	R:R:Y34	7.49	0	No	Yes	5	6	2	2
R:R:K294	R:R:V52	13.66	1	No	No	4	5	1	2
R:R:L105	R:R:Y102	3.52	0	No	Yes	6	7	2	2
R:R:L297	R:R:Y102	5.86	0	No	Yes	6	7	1	2
R:R:L105	R:R:R124	6.07	0	No	Yes	6	6	2	1
R:R:N108	R:R:R124	8.44	0	No	Yes	5	6	2	1
R:R:K294	R:R:T109	4.5	1	No	No	4	5	1	1
R:R:R124	R:R:T113	3.88	1	Yes	No	6	5	1	2
R:R:L116	R:R:R124	4.86	0	No	Yes	6	6	2	1
R:R:R124	R:R:W121	7	1	Yes	Yes	6	9	1	2
R:R:Q125	R:R:W121	15.33	1	Yes	Yes	4	9	1	2
R:R:L122	R:R:Y202	3.52	0	No	Yes	5	4	2	1
R:R:Q125	R:R:R124	9.35	1	Yes	Yes	4	6	1	1
R:R:Q125	R:R:Y202	6.76	1	Yes	Yes	4	4	1	1
R:R:D129	R:R:Y202	8.05	1	Yes	Yes	5	4	1	1
R:R:D129	R:R:Y206	8.05	1	Yes	Yes	5	7	1	2
R:R:T133	R:R:W210	6.06	0	No	No	6	6	2	1
R:R:P182	R:R:Y202	13.91	1	No	Yes	6	4	2	1
R:R:P182	R:R:Y206	19.47	1	No	Yes	6	7	2	2
R:R:E293	R:R:M198	14.89	0	No	No	4	3	1	2
R:R:A199	R:R:Y202	4	0	No	Yes	4	4	2	1
R:R:Y202	R:R:Y206	8.94	1	Yes	Yes	4	7	1	2
R:R:L207	R:R:L278	5.54	1	No	No	6	6	1	1
R:R:W210	R:R:W271	4.69	0	No	Yes	6	8	1	2
R:R:D129	R:R:G126	3.35	1	Yes	No	5	6	1	2
R:R:L207	R:R:V282	2.98	1	No	Yes	6	5	1	2
R:R:G110	R:R:T109	1.82	0	No	No	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7YU7_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.52
Number of Linked Nodes	268
Number of Links	287
Number of Hubs	28
Number of Links mediated by Hubs	118
Number of Communities	6
Number of Nodes involved in Communities	30
Number of Links involved in Communities	41

Path Summary
Number Of Nodes in MetaPath	55
Number Of Links MetaPath	54
Number of Shortest Paths	47658
Length Of Smallest Path	3
Average Path Length	12.6248
Length of Longest Path	27
Minimum Path Strength	1.12
Average Path Strength	6.92493
Maximum Path Strength	19.995
Minimum Path Correlation	0.7
Average Path Correlation	0.925266
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	52.531
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	35.4661
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	K6L
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	K6L
Name	[(2~{R})-2-[5-(2-hexylphenyl)pentanoylamino]-3-oxidanyl-propyl] dihydrogen phosphate
Synonyms
Identifier
Formula	C20 H34 N O6 P
Molecular Weight	415.461
SMILES
PubChem	141702624
Formal Charge	0
Total Atoms	62
Total Chiral Atoms	1
Total Bonds	62
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q92633
Sequence	>7YU7_nogp_Chain_R Q C F Y N E S I A F F Y N R S G K H L A T E W N T V S K L V M G L G I T V C I F I M L A N L L V M V A I Y V N R R F H F P I Y Y L M A N L A A A D F F A G L A Y F Y L M F N T G P N T R R L T V S T W L L R Q G L I D T S L T A S V A N L L A I A I E R H I T V F R M Q L H T R M S N R R V V V V I V V I W T M A I V M G A I P S V G W N C I C D I E N C S N M A P L Y S D S Y L V F W A I F N L V T F V V M V V L Y A H I F G Y V R Q R T M R M D T M M S L L K T V V I V L G A F I I C W T P G L V L L L L D V C C P Q C D V L A Y E K F F L L L A E F N S A M N P I I Y S Y R D K E M S A T F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	4Z34	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-9780307	-	-	3	2015-06-03	doi.org/10.1016/j.cell.2015.06.002
	4Z35	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-9910539	-	-	2.9	2015-06-03	doi.org/10.1016/j.cell.2015.06.002
	4Z36	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-3080573	-	-	2.9	2015-06-03	doi.org/10.1016/j.cell.2015.06.002
	9IZF	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	NKP	-	Gi1/β1/γ2	3.14	2025-01-01	doi.org/10.1016/j.jsb.2024.108164
	9IZF (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	NKP	-		3.14	2025-01-01	doi.org/10.1016/j.jsb.2024.108164
	9IZG	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	NKP	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.04	2025-01-01	doi.org/10.1016/j.jsb.2024.108164
	9IZG (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	NKP	-		3.04	2025-01-01	doi.org/10.1016/j.jsb.2024.108164
	7TD0	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-	Gi1/β1/γ2	2.83	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7TD0 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-		2.83	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7TD1	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-	Gi1/β1/γ2	3.08	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7TD1 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-		3.08	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7TD2	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-	Gi1/β1/γ2	3.11	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7TD2 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-		3.11	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7YU3	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/β1/γ2	3.5	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU3 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-		3.5	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU4	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-	-	3.7	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU5	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/β1/γ2	3.7	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU5 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-		3.7	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU6	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/β1/γ2	3.9	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU6 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-		3.9	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU7	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/β1/γ2	4.5	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU7 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-		4.5	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU8	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/β1/γ2	5.6	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	7YU8 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	ONO-0740556	-		5.6	2022-10-05	doi.org/10.1038/s41467-022-33121-2
	9J5V	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	CpY	-	Gi1/β1/γ2	2.86	2024-11-27	doi.org/10.1038/s42003-024-07152-y
	9J5V (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	CpY	-		2.86	2024-11-27	doi.org/10.1038/s42003-024-07152-y
	9IZH	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-	chim(NtGi2-G13)/β1/γ2	3.04	2025-01-01	doi.org/10.1016/j.jsb.2024.108164
	9IZH (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-		3.04	2025-01-01	doi.org/10.1016/j.jsb.2024.108164

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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You can also read or download a guide explaining the meaning of all files and numerical data.