psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D9	A:A:S6	8.83	No	No	0	4	7
2	A:A:K10	A:A:S6	4.59	No	No	0	3	7
3	A:A:K17	A:A:V13	6.07	No	No	0	4	3
4	A:A:E14	A:A:M18	4.06	No	No	0	3	4
5	A:A:I19	A:A:R15	6.26	No	No	0	9	5
6	A:A:R15	B:B:H91	3.39	No	No	0	5	5
7	A:A:S16	B:B:N88	7.45	No	Yes	0	7	7
8	A:A:S16	B:B:K89	3.06	No	Yes	0	7	9
9	A:A:I19	B:B:K89	8.72	No	Yes	0	9	9
10	A:A:D20	A:A:R24	5.96	No	No	0	6	3
11	A:A:D20	B:B:K89	8.3	No	Yes	0	6	9
12	A:A:R21	A:A:R24	5.33	No	No	0	4	3
13	A:A:E28	A:A:R24	3.49	No	No	0	4	3
14	A:A:D26	B:B:K78	9.68	No	No	0	5	8
15	A:A:K29	A:A:R32	8.66	No	No	0	1	4
16	A:A:E33	A:A:H195	13.54	No	No	0	6	4
17	A:A:E33	A:A:K197	9.45	No	Yes	0	6	6
18	A:A:L36	A:A:V34	2.98	No	Yes	5	7	5
19	A:A:L194	A:A:V34	4.47	Yes	Yes	5	4	5
20	A:A:T219	A:A:V34	4.76	No	Yes	0	7	5
21	A:A:V339	A:A:V34	3.21	Yes	Yes	5	8	5
22	A:A:L36	A:A:M198	4.24	No	Yes	0	7	7
23	A:A:L36	A:A:V339	2.98	No	Yes	5	7	8
24	A:A:L37	A:A:L39	8.3	Yes	No	1	9	9
25	A:A:L37	A:A:V201	2.98	Yes	No	1	9	9
26	A:A:F215	A:A:L37	13.4	Yes	Yes	1	9	9
27	A:A:I221	A:A:L37	9.99	Yes	Yes	1	8	9
28	A:A:L38	A:A:M198	4.24	No	Yes	0	8	7
29	A:A:D200	A:A:L38	6.79	No	No	0	9	8
30	A:A:I221	A:A:L39	4.28	Yes	No	1	8	9
31	A:A:I253	A:A:L39	4.28	No	No	0	8	9
32	A:A:F223	A:A:G40	7.53	Yes	No	0	9	9
33	A:A:A41	A:A:S246	3.42	No	No	0	7	9
34	A:A:E43	A:A:G42	3.27	No	No	0	9	8
35	A:A:E43	A:A:K46	4.05	No	No	0	9	9
36	A:A:G45	A:A:S44	3.71	No	No	0	9	9
37	A:A:K270	A:A:S44	4.59	Yes	No	0	9	9
38	A:A:D200	A:A:K46	5.53	No	No	0	9	9
39	A:A:Q52	A:A:T48	4.25	Yes	No	0	9	9
40	A:A:I49	A:A:M53	4.37	Yes	No	0	7	8
41	A:A:C224	A:A:I49	4.91	No	Yes	3	7	7
42	A:A:I49	A:A:N269	8.5	Yes	Yes	3	7	9
43	A:A:I49	A:A:T324	3.04	Yes	Yes	3	7	9
44	A:A:Q52	A:A:T324	4.25	Yes	Yes	3	9	9
45	A:A:D328	A:A:Q52	3.92	No	Yes	0	9	9
46	A:A:N331	A:A:Q52	5.28	No	Yes	3	8	9
47	A:A:A203	A:A:T182	3.36	No	No	0	9	7
48	A:A:I184	B:B:W99	8.22	No	Yes	0	9	9
49	A:A:E186	A:A:H188	11.08	No	No	1	9	3
50	A:A:E186	A:A:K197	8.1	No	Yes	1	9	6
51	A:A:E186	A:A:F199	8.16	No	Yes	1	9	5
52	A:A:H188	A:A:K197	9.17	No	Yes	1	3	6
53	A:A:F189	A:A:F196	16.08	No	No	0	9	7
54	A:A:F189	A:A:M198	3.73	No	Yes	0	9	7
55	A:A:H195	A:A:T190	8.21	No	No	0	4	3
56	A:A:F191	A:A:K192	14.89	Yes	No	5	5	4
57	A:A:F191	A:A:V332	11.8	Yes	No	0	5	7
58	A:A:F191	A:A:Q333	3.51	Yes	No	5	5	5
59	A:A:F191	A:A:F336	6.43	Yes	Yes	5	5	8
60	A:A:K192	A:A:Q333	4.07	No	No	5	4	5
61	A:A:F336	A:A:K192	6.2	Yes	No	5	8	4
62	A:A:F196	A:A:L194	9.74	No	Yes	0	7	4
63	A:A:F336	A:A:L194	4.87	Yes	Yes	5	8	4
64	A:A:L194	R:R:I128	7.14	Yes	No	5	4	7
65	A:A:F196	A:A:V339	3.93	No	Yes	0	7	8
66	A:A:F199	A:A:K197	4.96	Yes	Yes	1	5	6
67	A:A:F199	A:A:F215	4.29	Yes	Yes	1	5	9
68	A:A:F199	B:B:W99	10.02	Yes	Yes	1	5	9
69	A:A:V201	A:A:W211	7.36	No	Yes	1	9	9
70	A:A:F215	A:A:V201	3.93	Yes	No	1	9	9
71	A:A:Q204	A:A:S206	8.66	Yes	No	0	9	8
72	A:A:Q204	A:A:W211	6.57	Yes	Yes	1	9	9
73	A:A:Q204	B:B:G144	3.29	Yes	No	0	9	8
74	A:A:Q204	B:B:Y145	7.89	Yes	Yes	1	9	8
75	A:A:R208	A:A:W211	6	No	Yes	0	9	9
76	A:A:L249	A:A:R208	4.86	No	No	0	9	9
77	A:A:K209	B:B:D228	4.15	No	Yes	0	8	9
78	A:A:K210	B:B:Y145	3.58	Yes	Yes	1	9	8
79	A:A:K210	B:B:M188	8.64	Yes	Yes	1	9	8
80	A:A:K210	B:B:C204	4.85	Yes	Yes	1	9	7
81	A:A:K210	B:B:D228	8.3	Yes	Yes	1	9	9
82	A:A:K210	B:B:N230	4.2	Yes	No	1	9	9
83	A:A:K210	B:B:D246	5.53	Yes	Yes	1	9	9
84	A:A:F215	A:A:W211	5.01	Yes	Yes	1	9	9
85	A:A:W211	B:B:L117	4.56	Yes	No	0	9	9
86	A:A:W211	B:B:Y145	7.72	Yes	Yes	1	9	8
87	A:A:F259	A:A:I212	5.02	Yes	No	0	9	8
88	A:A:C214	A:A:H213	4.42	No	Yes	0	7	8
89	A:A:H213	A:A:W258	9.52	Yes	Yes	11	8	5
90	A:A:H213	B:B:Y59	6.53	Yes	Yes	11	8	8
91	A:A:H213	B:B:W332	7.41	Yes	Yes	11	8	9
92	A:A:C214	B:B:Q75	3.05	No	No	0	7	9
93	A:A:F215	A:A:V218	3.93	Yes	No	0	9	9
94	A:A:F215	B:B:W99	11.02	Yes	Yes	1	9	9
95	A:A:E216	A:A:W258	8.72	No	Yes	0	7	5
96	A:A:T262	A:A:V218	3.17	No	No	0	7	9
97	A:A:A220	A:A:S263	3.42	No	No	0	8	7
98	A:A:A220	A:A:I265	3.25	No	Yes	0	8	8
99	A:A:F259	A:A:I221	8.79	Yes	Yes	1	9	8
100	A:A:I221	A:A:T262	3.04	Yes	No	1	8	7
101	A:A:F267	A:A:I222	5.02	Yes	No	0	9	7
102	A:A:F223	A:A:V225	3.93	Yes	Yes	0	9	7
103	A:A:F223	A:A:L249	4.87	Yes	No	0	9	9
104	A:A:F223	A:A:F250	15	Yes	Yes	0	9	9
105	A:A:F223	A:A:L266	4.87	Yes	No	0	9	9
106	A:A:C224	A:A:N269	3.15	No	Yes	3	7	9
107	A:A:M243	A:A:V225	3.04	No	Yes	0	8	7
108	A:A:S246	A:A:V225	3.23	No	Yes	0	9	7
109	A:A:F307	A:A:V225	9.18	No	Yes	0	8	7
110	A:A:A226	A:A:D229	4.63	No	No	0	8	8
111	A:A:A226	A:A:K270	6.42	No	Yes	0	8	9
112	A:A:L227	A:A:L268	9.69	No	No	0	7	8
113	A:A:F274	A:A:L227	9.74	Yes	No	0	9	7
114	A:A:K270	A:A:S228	4.59	Yes	No	17	9	9
115	A:A:L273	A:A:S228	6.01	No	No	17	6	9
116	A:A:D229	A:A:R242	14.29	No	No	0	8	9
117	A:A:D231	A:A:Y230	6.9	No	Yes	12	9	8
118	A:A:F274	A:A:Y230	10.32	Yes	Yes	12	9	8
119	A:A:K277	A:A:Y230	4.78	No	Yes	0	9	8
120	A:A:I278	A:A:Y230	4.84	No	Yes	12	6	8
121	A:A:S281	A:A:Y230	5.09	No	Yes	12	7	8
122	A:A:L283	A:A:Y230	3.52	No	Yes	0	7	8
123	A:A:D231	A:A:L232	4.07	No	No	0	9	8
124	A:A:D231	A:A:S281	5.89	No	No	12	9	7
125	A:A:D237	A:A:V233	8.76	No	No	0	8	5
126	A:A:L234	A:A:R242	10.93	No	No	0	8	9
127	A:A:E236	A:A:E238	8.88	No	No	0	9	4
128	A:A:H244	A:A:N241	17.86	No	No	0	4	9
129	A:A:M243	A:A:M247	4.33	No	No	8	8	6
130	A:A:M243	A:A:Y287	5.99	No	Yes	8	8	7
131	A:A:H244	A:A:Y287	3.27	No	Yes	0	4	7
132	A:A:E245	A:A:K248	6.75	No	No	0	9	5
133	A:A:M247	A:A:Y287	5.99	No	Yes	8	6	7
134	A:A:L310	A:A:M247	5.65	No	No	0	4	6
135	A:A:I253	A:A:L249	4.28	No	No	0	8	9
136	A:A:F250	A:A:I264	5.02	Yes	No	0	9	6
137	A:A:F250	A:A:L310	8.53	Yes	No	0	9	4
138	A:A:F250	A:A:I319	3.77	Yes	No	0	9	5
139	A:A:D251	A:A:N255	9.42	No	No	0	5	8
140	A:A:D251	A:A:L310	8.14	No	No	0	5	4
141	A:A:C254	A:A:I264	3.27	No	No	0	5	6
142	A:A:C254	A:A:N311	4.72	No	Yes	18	5	8
143	A:A:C254	A:A:K317	6.47	No	No	18	5	7
144	A:A:K312	A:A:N255	6.99	No	No	0	5	8
145	A:A:N256	A:A:W258	9.04	No	Yes	0	8	5
146	A:A:F259	A:A:N256	4.83	Yes	No	0	9	8
147	A:A:K257	A:A:W258	16.24	No	Yes	0	4	5
148	A:A:W258	B:B:R314	7	Yes	No	11	5	8
149	A:A:W258	B:B:W332	4.69	Yes	Yes	11	5	9
150	A:A:F259	A:A:T262	3.89	Yes	No	1	9	7
151	A:A:R313	A:A:T260	5.17	No	No	0	4	3
152	A:A:S263	A:A:V342	8.08	No	No	0	7	7
153	A:A:F267	A:A:I265	5.02	Yes	Yes	3	9	8
154	A:A:I265	A:A:Y320	3.63	Yes	Yes	3	8	7
155	A:A:A338	A:A:I265	3.25	No	Yes	3	6	8
156	A:A:L266	A:A:L268	4.15	No	No	0	9	8
157	A:A:F307	A:A:L266	4.87	No	No	0	8	9
158	A:A:F267	A:A:H322	5.66	Yes	Yes	3	9	9
159	A:A:F267	A:A:F334	3.22	Yes	Yes	3	9	3
160	A:A:F323	A:A:L268	4.87	Yes	No	0	4	8
161	A:A:N269	A:A:T324	8.77	Yes	Yes	3	9	9
162	A:A:K270	A:A:L273	7.05	Yes	No	17	9	6
163	A:A:K271	A:A:Y296	8.36	No	Yes	0	5	4
164	A:A:D272	A:A:L273	6.79	No	No	0	9	6
165	A:A:F274	A:A:I278	8.79	Yes	No	12	9	6
166	A:A:F274	A:A:I303	3.77	Yes	No	0	9	7
167	A:A:E275	A:A:Y296	5.61	No	Yes	0	5	4
168	A:A:P282	A:A:T284	3.5	No	No	0	5	4
169	A:A:I285	A:A:P282	5.08	No	No	0	3	5
170	A:A:L283	A:A:Y290	11.72	No	Yes	0	7	7
171	A:A:C286	A:A:Y287	12.1	No	Yes	0	6	7
172	A:A:Y287	A:A:Y302	6.95	Yes	Yes	8	7	6
173	A:A:E289	A:A:Y302	3.37	No	Yes	8	6	6
174	A:A:E289	A:A:Q306	3.82	No	No	8	6	5
175	A:A:G292	A:A:Y290	4.35	No	Yes	8	7	7
176	A:A:E298	A:A:Y290	5.61	No	Yes	8	4	7
177	A:A:Y290	A:A:Y302	17.87	Yes	Yes	8	7	6
178	A:A:E298	A:A:G292	4.91	No	No	8	4	7
179	A:A:S293	A:A:T295	4.8	No	No	0	3	5
180	A:A:E298	A:A:S293	4.31	No	No	0	4	3
181	A:A:F323	A:A:Y296	4.13	Yes	Yes	0	4	4
182	A:A:Q306	A:A:Y302	12.4	No	Yes	8	5	6
183	A:A:E308	A:A:Q304	10.19	No	No	0	3	5
184	A:A:Q304	A:A:T321	9.92	No	No	0	5	5
185	A:A:K317	A:A:N311	8.39	No	Yes	18	7	8
186	A:A:I319	A:A:N311	4.25	No	Yes	0	5	8
187	A:A:D315	A:A:T316	7.23	No	No	0	3	3
188	A:A:E318	A:A:Y320	7.86	No	Yes	0	4	7
189	A:A:A338	A:A:Y320	5.34	No	Yes	3	6	7
190	A:A:D341	A:A:Y320	12.64	No	Yes	3	8	7
191	A:A:V342	A:A:Y320	5.05	No	Yes	0	7	7
192	A:A:K345	A:A:Y320	3.58	No	Yes	3	5	7
193	A:A:Y320	R:R:F368	13.41	Yes	Yes	3	7	5
194	A:A:H322	A:A:N331	5.1	Yes	No	3	9	8
195	A:A:F334	A:A:H322	20.36	Yes	Yes	3	3	9
196	A:A:N331	A:A:T324	7.31	No	Yes	3	8	9
197	A:A:K330	A:A:T327	3	No	No	0	4	8
198	A:A:D337	A:A:Q333	10.44	No	No	0	4	5
199	A:A:F334	R:R:R367	5.34	Yes	No	3	3	6
200	A:A:F334	R:R:F368	4.29	Yes	Yes	3	3	5
201	A:A:D337	A:A:F336	4.78	No	Yes	0	4	8
202	A:A:F336	A:A:T340	7.78	Yes	No	5	8	6
203	A:A:F336	R:R:I128	5.02	Yes	No	5	8	7
204	A:A:I343	A:A:V339	3.07	No	Yes	0	7	8
205	A:A:I344	A:A:T340	3.04	Yes	No	5	6	6
206	A:A:T340	R:R:P127	3.5	No	No	5	6	9
207	A:A:D341	A:A:K345	11.06	No	No	3	8	5
208	A:A:D341	R:R:F368	5.97	No	Yes	3	8	5
209	A:A:N346	A:A:V342	4.43	No	No	0	4	7
210	A:A:I343	A:A:N347	4.25	No	No	0	7	8
211	A:A:I343	R:R:Q131	10.98	No	No	0	7	9
212	A:A:I344	R:R:V124	3.07	Yes	No	0	6	9
213	A:A:I344	R:R:P127	6.77	Yes	No	5	6	9
214	A:A:F354	A:A:K345	7.44	Yes	No	0	5	5
215	A:A:N347	R:R:V123	2.96	No	No	0	8	5
216	A:A:N347	R:R:R134	3.62	No	Yes	0	8	9
217	A:A:L348	R:R:V124	4.47	No	No	0	9	9
218	A:A:F354	A:A:K349	9.93	Yes	No	0	5	5
219	A:A:D350	R:R:N57	6.73	No	No	0	4	8
220	A:A:C351	R:R:N57	4.72	No	No	0	4	8
221	A:A:C351	R:R:R120	5.57	No	Yes	0	4	9
222	A:A:L353	R:R:R120	9.72	No	Yes	0	7	9
223	A:A:F354	R:R:Q372	15.23	Yes	No	0	5	5
224	A:A:F354	R:R:T375	3.89	Yes	No	0	5	7
225	B:B:Q6	B:B:S2	5.78	No	No	0	1	5
226	B:B:D5	B:B:E3	9.09	No	No	0	1	5
227	B:B:E10	B:B:Q6	11.47	No	No	0	8	1
228	B:B:E10	B:B:L7	5.3	No	No	0	8	8
229	B:B:L7	G:G:A12	4.73	No	No	0	8	5
230	B:B:R8	G:G:Q11	4.67	No	No	0	3	3
231	B:B:E10	G:G:V16	5.7	No	No	0	8	7
232	B:B:E12	B:B:N16	5.26	No	No	0	4	1
233	B:B:L14	G:G:L19	8.3	Yes	No	0	8	9
234	B:B:L14	G:G:K20	4.23	Yes	No	0	8	6
235	B:B:N16	B:B:R19	12.05	No	No	0	1	4
236	B:B:I18	B:B:R22	6.26	No	No	0	7	6
237	B:B:I18	G:G:A23	3.25	No	No	0	7	8
238	B:B:A21	G:G:R27	5.53	No	No	0	4	8
239	B:B:D258	B:B:R22	13.1	No	No	19	7	6
240	B:B:R22	G:G:R27	7.46	No	No	19	6	8
241	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
242	B:B:D27	G:G:K29	11.06	No	No	0	8	4
243	B:B:A28	B:B:Q32	3.03	No	No	0	4	1
244	B:B:Q32	B:B:T29	11.34	No	No	0	1	3
245	B:B:L30	B:B:M262	5.65	No	Yes	0	5	4
246	B:B:M262	B:B:S31	4.6	Yes	No	0	4	1
247	B:B:L300	B:B:T34	5.9	Yes	No	21	6	5
248	B:B:T34	G:G:M38	4.52	No	No	21	5	4
249	B:B:I37	B:B:R283	3.76	No	No	0	2	9
250	B:B:I43	B:B:V40	3.07	No	Yes	14	3	3
251	B:B:L284	B:B:V40	2.98	Yes	Yes	14	5	3
252	B:B:D298	B:B:V40	4.38	No	Yes	0	9	3
253	B:B:V40	G:G:L51	2.98	Yes	Yes	14	3	6
254	B:B:I43	B:B:L284	4.28	No	Yes	14	3	5
255	B:B:A305	B:B:I43	3.25	No	No	0	4	3
256	B:B:L308	B:B:M45	4.24	No	No	22	7	4
257	B:B:M45	B:B:W339	3.49	No	Yes	22	4	9
258	B:B:K337	B:B:T47	4.5	No	No	0	6	3
259	B:B:T47	B:B:W339	7.28	No	Yes	0	3	9
260	B:B:N340	B:B:R48	18.08	Yes	Yes	4	9	7
261	B:B:R48	G:G:F61	4.28	Yes	Yes	4	7	8
262	B:B:R48	G:G:R62	4.26	Yes	Yes	0	7	7
263	B:B:R49	B:B:T87	5.17	No	No	0	7	5
264	B:B:I338	B:B:R49	5.01	No	No	4	5	7
265	B:B:R49	G:G:F61	8.55	No	Yes	4	7	8
266	B:B:R52	B:B:T50	3.88	No	No	0	7	3
267	B:B:L51	B:B:W82	19.36	No	Yes	0	9	9
268	B:B:L336	B:B:L51	6.92	No	No	0	7	9
269	B:B:F335	B:B:R52	6.41	No	No	0	4	7
270	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
271	B:B:H54	B:B:I58	7.95	Yes	No	10	9	9
272	B:B:H54	B:B:S72	9.76	Yes	No	0	9	9
273	B:B:H54	B:B:S74	8.37	Yes	Yes	10	9	9
274	B:B:D76	B:B:H54	6.3	Yes	Yes	10	9	9
275	B:B:H54	B:B:I80	13.26	Yes	Yes	10	9	8
276	B:B:H54	B:B:W82	3.17	Yes	Yes	10	9	9
277	B:B:A56	B:B:S74	3.42	No	Yes	10	7	9
278	B:B:A56	B:B:D76	3.09	No	Yes	10	7	9
279	B:B:K57	B:B:Y59	10.75	No	Yes	11	9	8
280	B:B:K57	B:B:W332	12.76	No	Yes	11	9	9
281	B:B:I58	B:B:S74	3.1	No	Yes	10	9	9
282	B:B:I58	B:B:S316	3.1	No	No	0	9	9
283	B:B:Q75	B:B:Y59	13.53	No	Yes	0	9	8
284	B:B:M101	B:B:Y59	3.59	No	Yes	0	9	8
285	B:B:W332	B:B:Y59	18.33	Yes	Yes	11	9	8
286	B:B:M61	B:B:W63	5.82	No	Yes	4	6	7
287	B:B:L70	B:B:M61	4.24	No	No	4	5	6
288	B:B:C317	B:B:M61	4.86	No	No	0	7	6
289	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
290	B:B:H62	B:B:R150	5.64	No	No	0	6	6
291	B:B:L70	B:B:W63	13.67	No	Yes	4	5	7
292	B:B:S84	B:B:W63	7.41	No	Yes	4	5	7
293	B:B:T321	B:B:W63	9.7	No	Yes	0	7	7
294	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
295	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
296	B:B:D66	B:B:R68	3.57	No	No	0	8	5
297	B:B:D66	B:B:L69	10.86	No	No	0	8	5
298	B:B:D323	B:B:S67	11.78	No	No	0	7	5
299	B:B:D83	B:B:R68	15.48	No	No	0	8	5
300	B:B:R68	B:B:Y85	22.64	No	No	0	5	4
301	B:B:L70	B:B:S84	3	No	No	4	5	5
302	B:B:I81	B:B:V71	3.07	No	No	0	7	8
303	B:B:C103	B:B:V71	3.42	No	No	0	8	8
304	B:B:V71	B:B:Y105	3.79	No	Yes	0	8	6
305	B:B:A73	B:B:V100	3.39	No	No	0	9	9
306	B:B:A73	B:B:C103	3.61	No	No	0	9	8
307	B:B:D76	B:B:S74	8.83	Yes	Yes	10	9	9
308	B:B:Q75	B:B:W99	5.48	No	Yes	0	9	9
309	B:B:D76	B:B:K78	4.15	Yes	No	0	9	8
310	B:B:L79	B:B:L95	9.69	No	Yes	7	7	8
311	B:B:C114	B:B:L79	3.17	No	No	7	8	7
312	B:B:I80	B:B:W82	16.44	Yes	Yes	10	8	9
313	B:B:I80	B:B:K89	4.36	Yes	Yes	10	8	9
314	B:B:I81	B:B:V90	6.14	No	No	0	7	5
315	B:B:K89	B:B:W82	11.6	Yes	Yes	10	9	9
316	B:B:D83	B:B:T86	10.12	No	No	0	8	6
317	B:B:I338	B:B:S84	3.1	No	No	4	5	5
318	B:B:Y85	G:G:P60	13.91	No	Yes	4	4	9
319	B:B:Y85	G:G:F61	5.16	No	Yes	4	4	8
320	B:B:N88	B:B:T86	13.16	Yes	No	0	7	6
321	B:B:H91	B:B:V90	6.92	No	No	0	5	5
322	B:B:H91	B:B:V133	4.15	No	Yes	0	5	4
323	B:B:I93	B:B:P94	3.39	No	No	0	7	5
324	B:B:I93	B:B:Y124	9.67	No	Yes	7	7	6
325	B:B:I93	B:B:V133	7.68	No	Yes	7	7	4
326	B:B:L95	B:B:V100	4.47	Yes	No	7	8	9
327	B:B:C114	B:B:L95	3.17	No	Yes	7	8	8
328	B:B:L95	B:B:Y124	7.03	Yes	Yes	7	8	6
329	B:B:R96	B:B:V135	3.92	No	No	7	6	4
330	B:B:E138	B:B:R96	4.65	No	No	7	6	6
331	B:B:S97	B:B:W99	3.71	No	Yes	0	8	9
332	B:B:D118	B:B:S97	4.42	No	No	0	9	8
333	B:B:S98	B:B:W99	6.18	No	Yes	0	8	9
334	B:B:L117	B:B:W99	10.25	No	Yes	0	9	9
335	B:B:C114	B:B:V100	3.42	No	No	7	8	9
336	B:B:C149	B:B:T102	5.07	No	No	0	8	8
337	B:B:G109	B:B:Y105	4.35	No	Yes	0	5	6
338	B:B:V112	B:B:Y105	3.79	No	Yes	0	8	6
339	B:B:A106	B:B:F151	9.71	No	Yes	0	6	9
340	B:B:N110	B:B:S108	10.43	No	No	0	4	6
341	B:B:D154	B:B:S108	4.42	No	No	0	6	6
342	B:B:N110	B:B:Y111	3.49	No	Yes	0	4	4
343	B:B:K127	B:B:N110	6.99	No	No	0	4	4
344	B:B:N125	B:B:Y111	10.47	No	Yes	0	4	4
345	B:B:S136	B:B:Y111	5.09	No	Yes	0	4	4
346	B:B:L126	B:B:V112	5.96	No	No	0	5	8
347	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
348	B:B:G115	B:B:L146	3.42	No	Yes	0	9	7
349	B:B:D118	B:B:I120	8.4	No	No	0	9	6
350	B:B:E138	B:B:I120	4.1	No	No	0	6	6
351	B:B:A140	B:B:I120	4.87	No	No	0	5	6
352	B:B:C121	B:B:L146	3.17	No	Yes	0	8	7
353	B:B:S122	B:B:Y124	7.63	No	Yes	0	8	6
354	B:B:I123	B:B:S136	4.64	No	No	0	6	4
355	B:B:V133	B:B:Y124	3.79	Yes	Yes	7	4	6
356	B:B:V135	B:B:Y124	3.79	No	Yes	7	4	6
357	B:B:N125	B:B:T128	5.85	No	Yes	0	4	3
358	B:B:L126	B:B:V133	2.98	No	Yes	0	5	4
359	B:B:E130	B:B:N132	3.94	No	No	0	3	3
360	B:B:E138	B:B:V135	4.28	No	No	7	6	4
361	B:B:G174	B:B:R137	4.5	No	No	0	4	5
362	B:B:L139	B:B:W169	15.94	No	Yes	0	9	8
363	B:B:H142	B:B:L146	5.14	No	Yes	1	9	7
364	B:B:H142	B:B:S161	9.76	No	Yes	1	9	9
365	B:B:H142	B:B:W169	12.7	No	Yes	1	9	8
366	B:B:G162	B:B:Y145	5.79	No	Yes	1	9	8
367	B:B:D186	B:B:Y145	12.64	Yes	Yes	1	9	8
368	B:B:M188	B:B:Y145	4.79	Yes	Yes	1	8	8
369	B:B:L146	B:B:T159	7.37	Yes	No	0	7	9
370	B:B:L146	B:B:S161	3	Yes	Yes	1	7	9
371	B:B:S147	B:B:S160	4.89	No	No	0	9	6
372	B:B:C148	B:B:R150	5.57	No	No	0	6	6
373	B:B:C148	B:B:L190	3.17	No	Yes	0	6	5
374	B:B:C149	B:B:T159	3.38	No	No	0	8	9
375	B:B:F151	B:B:I157	7.54	Yes	No	0	9	7
376	B:B:L152	B:B:Q156	5.32	Yes	No	0	3	5
377	B:B:L152	B:B:V213	4.47	Yes	No	0	3	4
378	B:B:D170	B:B:N155	5.39	No	No	23	9	3
379	B:B:I171	B:B:N155	5.66	No	No	0	6	3
380	B:B:E172	B:B:N155	9.2	No	No	23	6	3
381	B:B:L190	B:B:V158	2.98	Yes	No	0	5	5
382	B:B:S160	B:B:V187	6.46	No	Yes	0	6	9
383	B:B:L190	B:B:S160	3	Yes	No	0	5	6
384	B:B:G162	B:B:S161	3.71	No	Yes	1	9	9
385	B:B:D163	B:B:S161	8.83	No	Yes	0	9	9
386	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
387	B:B:D163	B:B:T165	10.12	No	No	0	9	7
388	B:B:G185	B:B:T164	3.64	No	No	0	5	6
389	B:B:T165	B:B:T181	4.71	No	No	0	7	2
390	B:B:C166	B:B:F180	4.19	No	Yes	0	8	7
391	B:B:C166	B:B:V187	3.42	No	Yes	0	8	9
392	B:B:A167	B:B:W169	3.89	No	Yes	1	4	8
393	B:B:A167	B:B:Q176	7.58	No	No	1	4	4
394	B:B:Q176	B:B:W169	13.14	No	Yes	1	4	8
395	B:B:D170	B:B:E172	5.2	No	No	23	9	6
396	B:B:D170	B:B:T173	7.23	No	No	0	9	5
397	B:B:Q176	B:B:T179	8.5	No	No	0	4	4
398	B:B:T177	B:B:T178	3.14	No	No	0	4	4
399	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
400	B:B:F180	B:B:F199	8.57	Yes	Yes	24	7	9
401	B:B:F180	B:B:W211	16.04	Yes	Yes	24	7	8
402	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
403	B:B:H183	B:B:V187	6.92	No	Yes	0	9	9
404	B:B:H183	B:B:S201	8.37	No	No	0	9	9
405	B:B:H183	B:B:W211	8.46	No	Yes	0	9	8
406	B:B:D205	B:B:T184	5.78	No	No	0	9	3
407	B:B:D186	B:B:M188	4.16	Yes	Yes	1	9	8
408	B:B:C204	B:B:D186	3.11	Yes	Yes	1	7	9
409	B:B:A203	B:B:V187	3.39	No	Yes	0	8	9
410	B:B:C204	B:B:M188	3.24	Yes	Yes	1	7	8
411	B:B:I229	B:B:S189	3.1	Yes	No	0	7	7
412	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
413	B:B:F199	B:B:L190	3.65	Yes	Yes	0	9	5
414	B:B:A193	B:B:D195	3.09	No	No	0	4	5
415	B:B:A193	B:B:F234	8.32	No	Yes	0	4	5
416	B:B:F234	B:B:P194	4.33	Yes	No	2	5	4
417	B:B:G238	B:B:P194	4.06	No	No	2	7	4
418	B:B:D195	B:B:R197	14.29	No	No	0	5	5
419	B:B:R197	B:B:R214	10.66	No	No	0	5	9
420	B:B:D212	B:B:L198	5.43	No	No	0	9	3
421	B:B:F199	B:B:W211	9.02	Yes	Yes	24	9	8
422	B:B:L210	B:B:V200	2.98	No	Yes	0	5	6
423	B:B:I232	B:B:V200	7.68	Yes	Yes	2	8	6
424	B:B:F234	B:B:V200	7.87	Yes	Yes	2	5	6
425	B:B:F241	B:B:V200	9.18	Yes	Yes	2	6	6
426	B:B:G202	B:B:I229	3.53	No	Yes	0	6	7
427	B:B:A203	B:B:D205	4.63	No	No	0	8	9
428	B:B:C204	B:B:D228	12.45	Yes	Yes	1	7	9
429	B:B:D205	B:B:S207	8.83	No	No	0	9	5
430	B:B:C218	B:B:K209	4.85	No	No	0	5	6
431	B:B:K209	B:B:T221	9.01	No	No	0	6	7
432	B:B:L210	B:B:R219	3.64	No	Yes	0	5	5
433	B:B:L210	B:B:L255	5.54	No	No	0	5	6
434	B:B:C218	B:B:W211	7.84	No	Yes	0	5	8
435	B:B:D212	B:B:E215	7.8	No	No	15	9	3
436	B:B:D212	B:B:R219	14.29	No	Yes	15	9	5
437	B:B:E215	B:B:M217	9.47	No	No	15	3	3
438	B:B:E215	B:B:R219	8.14	No	Yes	15	3	5
439	B:B:M217	B:B:R219	4.96	No	Yes	15	3	5
440	B:B:C218	G:G:Q18	4.58	No	No	0	5	9
441	B:B:F222	B:B:Q220	5.86	Yes	No	0	8	7
442	B:B:D258	B:B:Q220	11.75	No	No	0	7	7
443	B:B:Q220	G:G:I25	4.12	No	No	0	7	2
444	B:B:T221	G:G:E22	4.23	No	No	0	7	9
445	B:B:F222	B:B:F241	7.5	Yes	Yes	2	8	6
446	B:B:F222	B:B:F253	17.15	Yes	Yes	2	8	6
447	B:B:G224	B:B:R251	3	No	Yes	2	6	8
448	B:B:F253	B:B:G224	3.01	Yes	No	2	6	6
449	B:B:E260	B:B:G224	4.91	Yes	No	2	6	6
450	B:B:H225	B:B:I229	10.61	Yes	Yes	2	9	7
451	B:B:H225	B:B:T243	12.32	Yes	No	2	9	8
452	B:B:H225	B:B:S245	8.37	Yes	No	0	9	9
453	B:B:H225	B:B:R251	22.57	Yes	Yes	2	9	8
454	B:B:F253	B:B:H225	4.53	Yes	Yes	2	6	9
455	B:B:D246	B:B:S227	5.89	Yes	No	0	9	6
456	B:B:D228	B:B:D246	3.99	Yes	Yes	1	9	9
457	B:B:I229	B:B:T243	3.04	Yes	No	2	7	8
458	B:B:D246	B:B:N230	10.77	Yes	No	1	9	9
459	B:B:F241	B:B:I232	3.77	Yes	Yes	2	6	8
460	B:B:I232	B:B:T243	4.56	Yes	No	2	8	8
461	B:B:C233	B:B:F278	5.59	No	Yes	0	3	7
462	B:B:F234	B:B:G238	3.01	Yes	No	2	5	7
463	B:B:F234	B:B:L255	4.87	Yes	No	0	5	6
464	B:B:F235	B:B:P236	10.11	Yes	Yes	13	6	7
465	B:B:F235	B:B:F278	6.43	Yes	Yes	13	6	7
466	B:B:F235	B:B:G282	3.01	Yes	No	13	6	9
467	B:B:F235	G:G:L37	3.65	Yes	No	0	6	7
468	B:B:F235	G:G:Y40	3.09	Yes	Yes	13	6	6
469	B:B:F278	B:B:P236	4.33	Yes	Yes	13	7	7
470	B:B:G282	B:B:P236	4.06	No	Yes	13	9	7
471	B:B:P236	G:G:Y40	4.17	Yes	Yes	13	7	6
472	B:B:N237	B:B:N239	8.17	No	No	0	5	2
473	B:B:N237	G:G:Y40	16.28	No	Yes	0	5	6
474	B:B:N239	B:B:R256	7.23	No	Yes	0	2	9
475	B:B:F241	B:B:F253	7.5	Yes	Yes	2	6	6
476	B:B:F241	B:B:L255	3.65	Yes	No	0	6	6
477	B:B:A242	B:B:L285	3.15	No	No	0	4	6
478	B:B:G244	B:B:I273	5.29	No	No	0	5	6
479	B:B:D247	B:B:S245	8.83	No	No	0	9	9
480	B:B:D247	B:B:T249	11.56	No	No	2	9	6
481	B:B:D247	B:B:R251	7.15	No	Yes	2	9	8
482	B:B:R251	B:B:T249	9.06	Yes	No	2	8	6
483	B:B:S265	B:B:T249	4.8	No	No	0	2	6
484	B:B:C250	B:B:I273	3.27	No	No	0	8	6
485	B:B:F253	B:B:R251	3.21	Yes	Yes	2	6	8
486	B:B:E260	B:B:R251	4.65	Yes	Yes	2	6	8
487	B:B:L252	B:B:Y264	3.52	No	Yes	0	7	5
488	B:B:E260	B:B:F253	7	Yes	Yes	2	6	6
489	B:B:D254	B:B:R256	4.76	Yes	Yes	0	9	9
490	B:B:A257	B:B:D254	3.09	No	Yes	0	7	9
491	B:B:D254	B:B:L261	4.07	Yes	No	0	9	5
492	B:B:D254	G:G:A33	3.09	Yes	No	0	9	7
493	B:B:R256	G:G:I28	5.01	Yes	No	0	9	4
494	B:B:R256	G:G:D36	8.34	Yes	No	0	9	5
495	B:B:D258	G:G:R27	8.34	No	No	19	7	8
496	B:B:Q259	G:G:V30	5.73	No	No	0	6	8
497	B:B:M262	B:B:Y264	8.38	Yes	Yes	20	4	5
498	B:B:A302	B:B:M262	3.22	No	Yes	20	2	4
499	B:B:L285	B:B:Y264	3.52	No	Yes	0	6	5
500	B:B:W297	B:B:Y264	7.72	No	Yes	0	8	5
501	B:B:A302	B:B:Y264	4	No	Yes	20	2	5
502	B:B:H266	B:B:N268	8.93	No	No	0	4	4
503	B:B:H266	B:B:I269	5.3	No	No	0	4	4
504	B:B:I269	B:B:Y289	8.46	No	Yes	0	4	7
505	B:B:C271	B:B:Y289	4.03	No	Yes	0	5	7
506	B:B:C271	B:B:D290	3.11	No	Yes	0	5	6
507	B:B:D290	B:B:G272	3.35	Yes	No	0	6	4
508	B:B:I273	B:B:Y289	7.25	No	Yes	0	6	7
509	B:B:S275	B:B:T274	3.2	No	No	0	8	8
510	B:B:D290	B:B:T274	4.34	Yes	No	0	6	8
511	B:B:T274	B:B:V315	3.17	No	No	0	8	7
512	B:B:L318	B:B:S275	6.01	Yes	No	0	6	8
513	B:B:L318	B:B:S277	3	Yes	No	0	6	5
514	B:B:S277	B:B:V320	4.85	No	No	0	5	7
515	B:B:F278	B:B:G282	3.01	Yes	No	13	7	9
516	B:B:F278	B:B:L285	13.4	Yes	No	0	7	6
517	B:B:L284	B:B:S279	3	Yes	No	0	5	9
518	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
519	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
520	B:B:D298	B:B:R283	15.48	No	No	0	9	9
521	B:B:L300	B:B:R283	4.86	Yes	No	0	6	9
522	B:B:L284	B:B:V296	5.96	Yes	No	0	5	5
523	B:B:L284	G:G:L51	4.15	Yes	Yes	14	5	6
524	B:B:L286	B:B:V296	7.45	No	No	0	7	5
525	B:B:L286	B:B:V327	2.98	No	No	0	7	6
526	B:B:C294	B:B:G288	3.92	No	No	0	5	7
527	B:B:G288	B:B:V315	3.68	No	No	0	7	7
528	B:B:N295	B:B:Y289	8.14	No	Yes	0	6	7
529	B:B:W297	B:B:Y289	9.65	No	Yes	0	8	7
530	B:B:D290	B:B:R314	19.06	Yes	No	0	6	8
531	B:B:D291	B:B:N293	5.39	No	No	0	8	5
532	B:B:A309	B:B:N293	3.13	No	No	0	3	5
533	B:B:C294	B:B:L308	3.17	No	No	0	5	7
534	B:B:N295	B:B:R304	7.23	No	No	25	6	5
535	B:B:N295	B:B:V307	7.39	No	No	25	6	3
536	B:B:R304	B:B:W297	8	No	No	0	5	8
537	B:B:D298	B:B:K301	9.68	No	No	0	9	5
538	B:B:L300	G:G:M38	4.24	Yes	No	21	6	4
539	B:B:L300	G:G:C41	3.17	Yes	No	0	6	7
540	B:B:D303	B:B:K301	4.15	No	No	0	2	5
541	B:B:R304	B:B:V307	3.92	No	No	25	5	3
542	B:B:L308	B:B:W339	20.5	No	Yes	22	7	9
543	B:B:H311	B:B:T329	8.21	Yes	Yes	0	9	8
544	B:B:H311	B:B:S331	6.97	Yes	No	9	9	9
545	B:B:D333	B:B:H311	7.56	Yes	Yes	9	9	9
546	B:B:H311	B:B:K337	5.24	Yes	No	0	9	6
547	B:B:D312	B:B:D333	6.65	No	Yes	9	5	9
548	B:B:D312	R:R:K445	5.53	No	Yes	9	5	7
549	B:B:D312	R:R:Q448	3.92	No	No	9	5	7
550	B:B:N313	B:B:S331	2.98	No	No	0	7	9
551	B:B:N313	B:B:W332	6.78	No	Yes	0	7	9
552	B:B:R314	B:B:W332	15.99	No	Yes	11	8	9
553	B:B:T329	B:B:V315	3.17	Yes	No	0	8	7
554	B:B:C317	B:B:S316	3.44	No	No	0	7	9
555	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
556	B:B:L318	B:B:V327	2.98	Yes	No	0	6	6
557	B:B:L318	B:B:T329	5.9	Yes	Yes	0	6	8
558	B:B:V320	B:B:V327	4.81	No	No	0	7	6
559	B:B:D323	B:B:T321	7.23	No	No	0	7	7
560	B:B:D323	B:B:M325	9.7	No	No	0	7	5
561	B:B:M325	G:G:P49	5.03	No	No	0	5	7
562	B:B:M325	G:G:P60	3.35	No	Yes	0	5	9
563	B:B:A326	B:B:N340	4.69	No	Yes	4	7	9
564	B:B:A326	G:G:F61	4.16	No	Yes	4	7	8
565	B:B:T329	B:B:W339	4.85	Yes	Yes	0	8	9
566	B:B:D333	B:B:S331	10.31	Yes	No	9	9	9
567	B:B:D333	B:B:F335	13.14	Yes	No	0	9	4
568	B:B:F335	R:R:Q53	4.68	No	No	0	4	6
569	B:B:I338	G:G:F61	7.54	No	Yes	4	5	8
570	B:B:N340	G:G:N59	5.45	Yes	Yes	4	9	9
571	B:B:N340	G:G:F61	3.62	Yes	Yes	4	9	8
572	G:G:I9	G:G:R13	20.04	No	No	0	2	6
573	G:G:A12	G:G:Q11	3.03	No	No	0	5	3
574	G:G:E17	G:G:R13	10.47	No	No	0	6	6
575	G:G:D26	G:G:I28	4.2	No	No	0	1	4
576	G:G:I28	G:G:K32	4.36	No	No	0	4	5
577	G:G:K29	G:G:S31	12.24	No	No	0	4	9
578	G:G:D36	G:G:K32	5.53	No	No	0	5	5
579	G:G:H44	G:G:Y40	10.89	No	Yes	0	6	6
580	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
581	G:G:D48	G:G:L51	5.43	Yes	Yes	0	9	6
582	G:G:P53	G:G:T52	5.25	No	No	0	8	4
583	G:G:P55	G:G:V54	3.53	No	No	0	5	6
584	G:G:N59	G:G:V54	2.96	Yes	No	0	9	6
585	G:G:P55	G:G:S57	3.56	No	No	26	5	6
586	G:G:E58	G:G:P55	3.14	No	No	26	5	5
587	G:G:A56	G:G:R62	5.53	No	Yes	0	4	7
588	G:G:E58	G:G:S57	7.19	No	No	26	5	6
589	G:G:N59	G:G:P60	6.52	Yes	Yes	4	9	9
590	G:G:F61	G:G:N59	6.04	Yes	Yes	4	8	9
591	G:G:N59	G:G:R62	8.44	Yes	Yes	0	9	7
592	G:G:F61	G:G:P60	4.33	Yes	Yes	4	8	9
593	G:G:E63	G:G:R62	8.14	No	Yes	0	6	7
594	R:R:E20	R:R:W18	4.36	No	No	0	4	1
595	R:R:E20	R:R:P21	3.14	No	No	0	4	6
596	R:R:P21	R:R:P22	5.84	No	No	0	6	4
597	R:R:P22	R:R:W416	5.4	No	Yes	0	4	7
598	R:R:H418	R:R:P22	3.05	No	No	0	4	4
599	R:R:M27	R:R:V23	3.04	No	No	0	6	4
600	R:R:H418	R:R:S26	9.76	No	No	0	4	8
601	R:R:A422	R:R:I29	4.87	No	No	0	8	7
602	R:R:L30	R:R:L75	4.15	No	Yes	0	6	9
603	R:R:L32	R:R:L36	8.3	No	No	0	6	8
604	R:R:F430	R:R:L32	3.65	No	No	0	7	6
605	R:R:C72	R:R:T33	3.38	No	No	0	8	8
606	R:R:L75	R:R:T33	4.42	Yes	No	27	9	8
607	R:R:S425	R:R:T33	3.2	No	No	27	8	8
608	R:R:F34	R:R:L38	8.53	No	Yes	0	7	7
609	R:R:F34	R:R:P76	5.78	No	No	0	7	9
610	R:R:L35	R:R:L36	4.15	No	No	0	6	8
611	R:R:G37	R:R:N41	3.39	No	Yes	0	9	9
612	R:R:C429	R:R:G37	3.92	No	No	0	9	9
613	R:R:L38	R:R:L69	4.15	Yes	No	6	7	7
614	R:R:L38	R:R:L73	4.15	Yes	No	6	7	8
615	R:R:N41	R:R:T65	5.85	Yes	No	0	9	9
616	R:R:D68	R:R:N41	6.73	Yes	Yes	6	9	9
617	R:R:N41	R:R:P432	11.4	Yes	No	6	9	9
618	R:R:L43	R:R:V47	2.98	No	No	0	8	8
619	R:R:I450	R:R:L43	7.14	No	No	0	4	8
620	R:R:T65	R:R:V44	7.93	No	No	0	9	9
621	R:R:F442	R:R:V44	9.18	Yes	No	0	9	9
622	R:R:L50	R:R:W46	6.83	No	Yes	0	4	6
623	R:R:K51	R:R:W46	5.8	No	Yes	9	9	6
624	R:R:S449	R:R:W46	4.94	No	Yes	9	9	6
625	R:R:I453	R:R:W46	4.7	No	Yes	0	7	6
626	R:R:F442	R:R:V47	6.55	Yes	No	0	9	8
627	R:R:K445	R:R:V47	3.04	Yes	No	0	7	8
628	R:R:A48	R:R:L62	4.73	No	No	0	7	8
629	R:R:G49	R:R:R54	3	No	No	0	7	7
630	R:R:G49	R:R:L62	3.42	No	No	0	7	8
631	R:R:K51	R:R:S449	4.59	No	No	9	9	9
632	R:R:M52	R:R:T58	3.01	No	No	0	9	8
633	R:R:D441	R:R:M52	5.54	No	No	0	7	9
634	R:R:T55	R:R:T58	9.42	No	No	0	9	8
635	R:R:R134	R:R:V56	3.92	Yes	No	0	9	8
636	R:R:A139	R:R:V56	5.09	No	No	0	7	8
637	R:R:H63	R:R:I59	3.98	Yes	No	0	8	6
638	R:R:A115	R:R:W60	5.19	No	Yes	0	7	8
639	R:R:I116	R:R:W60	7.05	No	Yes	0	9	8
640	R:R:D119	R:R:W60	3.35	No	Yes	0	9	8
641	R:R:A139	R:R:W60	3.89	No	Yes	0	7	8
642	R:R:I142	R:R:W60	4.7	No	Yes	0	5	8
643	R:R:C143	R:R:W60	6.53	No	Yes	0	8	8
644	R:R:A436	R:R:F61	4.16	No	No	0	8	8
645	R:R:H63	R:R:L112	5.14	Yes	No	0	8	9
646	R:R:C143	R:R:H63	14.74	No	Yes	0	8	8
647	R:R:H63	R:R:W147	5.29	Yes	No	0	8	9
648	R:R:D68	R:R:L64	9.5	Yes	No	6	9	9
649	R:R:L113	R:R:L64	5.54	No	No	6	8	9
650	R:R:L64	R:R:Y435	3.52	No	Yes	6	9	9
651	R:R:A67	R:R:S109	3.42	No	No	0	9	9
652	R:R:D68	R:R:S428	7.36	Yes	No	6	9	9
653	R:R:D68	R:R:N431	10.77	Yes	No	6	9	9
654	R:R:D68	R:R:P432	4.83	Yes	No	6	9	9
655	R:R:L69	R:R:L73	5.54	No	No	6	7	8
656	R:R:L70	R:R:N105	10.98	No	No	0	6	9
657	R:R:C71	R:R:S428	5.16	No	No	0	8	9
658	R:R:I102	R:R:S74	3.1	Yes	No	0	8	9
659	R:R:L75	R:R:P76	3.28	Yes	No	0	9	9
660	R:R:L75	R:R:S425	12.01	Yes	No	27	9	8
661	R:R:I102	R:R:S78	9.29	Yes	No	0	8	8
662	R:R:I421	R:R:S78	3.1	Yes	No	0	4	8
663	R:R:H81	R:R:W88	12.7	No	Yes	0	7	9
664	R:R:H81	R:R:P99	6.1	No	No	0	7	8
665	R:R:L82	R:R:Q85	6.65	No	No	0	7	5
666	R:R:D417	R:R:L82	4.07	No	No	0	8	7
667	R:R:I421	R:R:L82	4.28	Yes	No	0	4	7
668	R:R:H169	R:R:Q87	12.36	Yes	No	0	3	6
669	R:R:W88	R:R:Y90	11.58	Yes	Yes	28	9	7
670	R:R:L94	R:R:W88	9.11	No	Yes	28	8	9
671	R:R:C95	R:R:W88	5.22	No	Yes	0	9	9
672	R:R:P89	R:R:Y90	5.56	No	Yes	0	8	7
673	R:R:L94	R:R:Y90	4.69	No	Yes	28	8	7
674	R:R:K96	R:R:R92	8.66	Yes	No	0	8	1
675	R:R:F93	R:R:K96	4.96	No	Yes	29	4	8
676	R:R:F158	R:R:F93	8.57	No	No	29	8	4
677	R:R:I98	R:R:L94	7.14	Yes	No	0	8	8
678	R:R:C95	R:R:R161	4.18	No	Yes	0	9	8
679	R:R:C172	R:R:C95	7.28	No	No	0	8	9
680	R:R:F158	R:R:K96	12.41	No	Yes	29	8	8
681	R:R:K96	R:R:R161	3.71	Yes	Yes	0	8	8
682	R:R:I101	R:R:L97	4.28	No	No	0	5	6
683	R:R:I98	R:R:P99	5.08	Yes	No	0	8	8
684	R:R:C154	R:R:S100	5.16	No	No	0	8	8
685	R:R:F158	R:R:S100	5.28	No	No	0	8	8
686	R:R:I101	R:R:N105	4.25	No	No	0	5	9
687	R:R:V103	R:R:V157	4.81	No	No	0	5	9
688	R:R:C154	R:R:L104	4.76	No	No	0	8	8
689	R:R:A424	R:R:M106	3.22	No	No	0	9	9
690	R:R:F107	R:R:F111	9.65	Yes	Yes	0	8	8
691	R:R:F107	R:R:M153	9.95	Yes	No	0	8	8
692	R:R:F107	R:R:R340	6.41	Yes	No	0	8	9
693	R:R:A108	R:R:W147	7.78	No	No	0	9	9
694	R:R:P348	R:R:V110	3.53	Yes	No	0	9	9
695	R:R:V110	R:R:W390	4.9	No	Yes	0	9	9
696	R:R:F111	R:R:I146	5.02	Yes	No	0	8	8
697	R:R:L113	R:R:Y435	5.86	No	Yes	6	8	9
698	R:R:P348	R:R:T114	3.5	Yes	No	0	9	8
699	R:R:I351	R:R:T114	4.56	No	No	0	6	8
700	R:R:I116	R:R:R120	7.52	No	Yes	0	9	9
701	R:R:M352	R:R:S117	4.6	No	No	0	8	9
702	R:R:C355	R:R:S117	3.44	No	No	0	9	9
703	R:R:D119	R:R:R134	3.57	No	Yes	0	9	9
704	R:R:R120	R:R:Y435	8.23	Yes	Yes	0	9	9
705	R:R:C121	R:R:C355	7.28	No	No	0	9	9
706	R:R:L122	R:R:W129	3.42	No	No	0	7	6
707	R:R:R362	R:R:V124	3.92	No	No	0	7	9
708	R:R:F125	R:R:K126	9.93	No	No	0	6	6
709	R:R:F125	R:R:F358	6.43	No	No	0	6	6
710	R:R:H133	R:R:W129	16.93	No	No	0	8	6
711	R:R:M138	R:R:W129	5.82	No	No	0	6	6
712	R:R:C130	R:R:R134	6.96	No	Yes	0	7	9
713	R:R:H133	R:R:N132	3.83	No	No	0	8	8
714	R:R:G137	R:R:N135	3.39	No	No	0	5	5
715	R:R:I142	R:R:M138	4.37	No	No	0	5	6
716	R:R:F151	R:R:I155	5.02	No	No	0	5	5
717	R:R:M153	R:R:V343	3.04	No	No	0	8	4
718	R:R:I155	R:R:P156	3.39	No	No	0	5	9
719	R:R:I336	R:R:V157	3.07	No	No	0	7	9
720	R:R:V159	R:R:Y160	5.05	No	No	0	4	8
721	R:R:P332	R:R:Y160	8.34	No	No	0	4	8
722	R:R:G173	R:R:R161	3	No	Yes	0	1	8
723	R:R:R161	R:R:Y174	21.61	Yes	No	0	8	7
724	R:R:E162	R:R:K175	4.05	No	No	0	5	5
725	R:R:I163	R:R:N170	4.25	No	No	0	6	4
726	R:R:F164	R:R:R171	14.97	No	Yes	0	3	1
727	R:R:F164	R:R:G173	3.01	No	No	0	3	1
728	R:R:F164	R:R:K175	12.41	No	No	0	3	5
729	R:R:N168	R:R:T166	4.39	No	No	16	5	1
730	R:R:H169	R:R:T166	13.69	Yes	No	16	3	1
731	R:R:R171	R:R:T166	6.47	Yes	No	16	1	1
732	R:R:D167	R:R:N168	5.39	No	No	0	3	5
733	R:R:H169	R:R:N168	16.58	Yes	No	16	3	5
734	R:R:H169	R:R:R171	5.64	Yes	Yes	16	3	1
735	R:R:F176	R:R:P332	15.89	No	No	0	4	4
736	R:R:P332	R:R:T331	3.5	No	No	0	4	4
737	R:R:L401	R:R:V334	7.45	No	No	0	7	4
738	R:R:I338	R:R:T337	3.04	No	No	0	6	7
739	R:R:L401	R:R:T337	5.9	No	No	0	7	7
740	R:R:R340	R:R:Y393	6.17	No	No	0	9	9
741	R:R:H394	R:R:L341	3.86	No	No	0	9	6
742	R:R:L341	R:R:V398	4.47	No	No	0	6	7
743	R:R:L346	R:R:V342	4.47	No	No	0	8	6
744	R:R:G344	R:R:P348	4.06	No	Yes	0	9	9
745	R:R:F345	R:R:S349	5.28	No	No	0	9	4
746	R:R:F345	R:R:T391	6.49	No	No	0	9	6
747	R:R:F345	R:R:H394	13.58	No	No	0	9	9
748	R:R:L347	R:R:P348	3.28	No	Yes	0	7	9
749	R:R:I351	R:R:L347	7.14	No	No	0	6	7
750	R:R:L387	R:R:S349	3	No	No	0	6	4
751	R:R:M352	R:R:Y356	3.59	No	Yes	0	8	9
752	R:R:F386	R:R:M352	8.71	No	No	0	9	8
753	R:R:I353	R:R:V383	3.07	No	No	0	5	8
754	R:R:A379	R:R:Y356	5.34	No	Yes	0	7	9
755	R:R:V382	R:R:Y356	3.79	No	Yes	0	8	9
756	R:R:V383	R:R:Y356	3.79	No	Yes	0	8	9
757	R:R:F358	R:R:R362	13.9	No	No	0	6	7
758	R:R:Q364	R:R:V360	5.73	No	No	0	5	6
759	R:R:F361	R:R:R365	14.97	No	No	0	4	4
760	R:R:M363	R:R:Q372	9.52	No	No	0	7	5
761	R:R:F368	R:R:R367	13.9	Yes	No	3	5	6
762	R:R:K370	R:R:Q372	4.07	No	No	0	7	5
763	R:R:F376	R:R:V380	9.18	No	No	0	4	3
764	R:R:L438	R:R:V378	2.98	No	No	0	7	8
765	R:R:V382	R:R:Y435	3.79	No	Yes	0	8	9
766	R:R:L387	R:R:V383	2.98	No	No	0	6	8
767	R:R:L434	R:R:V385	4.47	No	No	0	9	7
768	R:R:F386	R:R:W390	16.04	No	Yes	0	9	9
769	R:R:C389	R:R:L423	4.76	No	No	0	9	8
770	R:R:C389	R:R:N427	9.45	No	No	0	9	9
771	R:R:H394	R:R:W390	3.17	No	Yes	0	9	9
772	R:R:N427	R:R:W390	12.43	No	Yes	0	9	9
773	R:R:P392	R:R:T391	5.25	No	No	0	9	6
774	R:R:I395	R:R:T391	3.04	No	No	0	5	6
775	R:R:L423	R:R:P392	3.28	No	No	0	8	9
776	R:R:C420	R:R:Y393	6.72	No	No	0	6	9
777	R:R:I421	R:R:Y393	3.63	Yes	No	0	4	9
778	R:R:F396	R:R:L413	6.09	No	No	0	4	7
779	R:R:C420	R:R:F396	4.19	No	No	0	6	4
780	R:R:G397	R:R:S400	3.71	No	No	0	8	2
781	R:R:L401	R:R:S400	3	No	No	0	7	2
782	R:R:L409	R:R:T403	8.84	No	Yes	0	3	2
783	R:R:D404	R:R:P405	4.83	No	No	0	4	4
784	R:R:D404	R:R:E406	3.9	No	No	0	4	1
785	R:R:D404	R:R:T407	8.67	No	No	0	4	7
786	R:R:P408	R:R:T407	5.25	No	No	0	4	7
787	R:R:T412	R:R:W416	4.85	No	Yes	0	6	7
788	R:R:V419	R:R:W416	6.13	No	Yes	0	5	7
789	R:R:C420	R:R:D417	3.11	No	No	0	6	8
790	R:R:H418	R:R:V419	6.92	No	No	0	4	5
791	R:R:A426	R:R:F430	4.16	No	No	0	8	7
792	R:R:N427	R:R:N431	9.54	No	No	0	9	9
793	R:R:N431	R:R:S428	2.98	No	No	6	9	9
794	R:R:F433	R:R:L437	4.87	No	No	0	6	7
795	R:R:K440	R:R:R443	4.95	No	No	0	7	9
796	R:R:K445	R:R:Q448	5.42	Yes	No	9	7	7
797	R:R:K445	R:R:S449	3.06	Yes	No	9	7	9
798	R:R:I450	R:R:R447	6.26	No	No	0	4	5
799	B:B:L152	B:B:T196	2.95	Yes	No	0	3	1
800	R:R:L118	R:R:T114	2.95	No	No	0	8	8
801	R:R:L333	R:R:T337	2.95	No	No	0	3	7
802	R:R:L413	R:R:T403	2.95	No	Yes	0	7	2
803	B:B:I123	B:B:I171	2.94	No	No	0	6	6
804	R:R:D68	R:R:S109	2.94	Yes	No	0	9	9
805	R:R:I102	R:R:I98	2.94	Yes	Yes	0	8	8
806	R:R:I142	R:R:I146	2.94	No	No	0	5	8
807	G:G:A43	G:G:H44	2.93	No	No	0	4	6
808	A:A:I222	A:A:M198	2.92	No	Yes	0	7	7
809	A:A:I344	R:R:M363	2.92	Yes	No	0	6	7
810	B:B:I33	G:G:M38	2.92	No	No	0	3	4
811	R:R:I102	R:R:M106	2.92	Yes	No	0	8	9
812	R:R:N170	R:R:T165	2.92	No	No	0	4	4
813	A:A:D261	A:A:T260	2.89	No	No	0	4	3
814	A:A:D261	A:A:T316	2.89	No	No	0	4	3
815	B:B:D163	B:B:T143	2.89	No	No	0	9	5
816	B:B:E3	B:B:S2	2.87	No	No	0	5	5
817	A:A:L23	B:B:I80	2.85	No	Yes	0	6	8
818	B:B:I18	G:G:L19	2.85	No	No	0	7	9
819	B:B:I123	B:B:L139	2.85	No	No	0	6	9
820	R:R:I421	R:R:L79	2.85	Yes	No	0	4	6
821	R:R:I395	R:R:L399	2.85	No	No	0	5	9
822	R:R:I450	R:R:L454	2.85	No	No	0	4	8
823	B:B:Q175	B:B:T173	2.83	No	No	0	4	5
824	B:B:K15	G:G:L19	2.82	No	No	0	6	9
825	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
826	B:B:G182	B:B:W211	2.81	No	Yes	0	6	8
827	B:B:G310	B:B:W339	2.81	No	Yes	0	5	9
828	A:A:K314	A:A:N311	2.8	No	Yes	0	3	8
829	R:R:M138	R:R:N135	2.8	No	No	0	6	5
830	R:R:P156	R:R:Y160	2.78	No	No	0	9	8
831	A:A:A299	A:A:F274	2.77	No	Yes	0	7	9
832	A:A:A300	A:A:F323	2.77	No	Yes	0	5	4
833	B:B:A104	B:B:F151	2.77	No	Yes	0	7	9
834	B:B:L152	B:B:L168	2.77	Yes	No	0	3	6
835	B:B:L152	B:B:L192	2.77	Yes	No	0	3	5
836	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
837	R:R:L66	R:R:L70	2.77	No	No	0	4	6
838	R:R:A150	R:R:F111	2.77	No	Yes	0	9	8
839	R:R:A436	R:R:F442	2.77	No	Yes	0	8	9
840	R:R:D441	R:R:K444	2.77	No	No	0	7	5
841	R:R:L69	R:R:N41	2.75	No	Yes	6	7	9
842	B:B:I33	B:B:Q32	2.74	No	No	0	3	1
843	G:G:E22	G:G:I25	2.73	No	No	0	9	2
844	G:G:D48	G:G:L50	2.71	Yes	No	0	9	9
845	B:B:F234	B:B:S191	2.64	Yes	No	0	5	8
846	A:A:F267	A:A:V335	2.62	Yes	No	0	9	8
847	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
848	R:R:F107	R:R:V103	2.62	Yes	No	0	8	5
849	R:R:F376	R:R:V360	2.62	No	No	0	4	6
850	B:B:R134	B:B:T128	2.59	No	Yes	0	3	3
851	R:R:I59	R:R:R54	2.51	No	No	0	6	7
852	A:A:F199	A:A:K35	2.48	Yes	No	0	5	9
853	A:A:K317	A:A:R313	2.48	No	No	0	7	4
854	R:R:F151	R:R:L104	2.44	No	No	0	5	8
855	R:R:F442	R:R:L437	2.44	Yes	No	0	9	7
856	B:B:L7	G:G:R13	2.43	No	No	0	8	6
857	B:B:L139	B:B:R137	2.43	No	No	0	9	5
858	A:A:R32	R:R:N132	2.41	No	No	0	4	8
859	B:B:D20	B:B:R19	2.38	No	No	0	2	4
860	A:A:F323	A:A:Q304	2.34	Yes	No	0	4	5
861	R:R:L84	R:R:Y90	2.34	No	Yes	0	8	7
862	R:R:L434	R:R:Y435	2.34	No	Yes	0	9	9
863	B:B:E226	B:B:R251	2.33	No	Yes	0	3	8
864	R:R:L25	R:R:W416	2.28	No	Yes	0	5	7
865	A:A:G352	R:R:G439	2.11	Yes	No	0	8	9
866	B:B:G115	B:B:G116	2.11	No	No	0	9	9
867	B:B:F151	B:B:Y111	2.06	Yes	Yes	0	9	4
868	B:B:G324	G:G:P49	2.03	No	No	0	9	7
869	R:R:G40	R:R:P39	2.03	No	No	0	9	7
870	R:R:F396	R:R:W416	2	No	Yes	0	4	7
871	B:B:C317	B:B:G330	1.96	No	No	0	7	5
872	R:R:C143	R:R:G144	1.96	No	No	0	8	5
873	A:A:A30	A:A:G27	1.95	No	No	0	3	5
874	B:B:A140	B:B:G141	1.95	No	No	0	5	5
875	B:B:A203	B:B:G185	1.95	No	No	0	8	5
876	B:B:A106	B:B:P107	1.87	No	No	0	6	6
877	R:R:A335	R:R:P330	1.87	No	No	0	5	2
878	B:B:G77	B:B:S98	1.86	No	No	0	8	8
879	B:B:G41	B:B:V40	1.84	No	Yes	0	1	3
880	B:B:G244	B:B:V276	1.84	No	No	0	5	6
881	A:A:G183	A:A:T182	1.82	No	No	0	9	7
882	B:B:G131	B:B:T128	1.82	No	Yes	0	4	3
883	R:R:G410	R:R:T403	1.82	No	Yes	0	3	2
884	B:B:A60	B:B:C103	1.81	No	No	0	7	8
885	A:A:P282	A:A:S281	1.78	No	No	0	5	7
886	B:B:P107	B:B:T65	1.75	No	No	0	6	1
887	A:A:G202	A:A:K46	1.74	No	No	0	9	9
888	A:A:G352	R:R:K440	1.74	Yes	No	0	8	7
889	B:B:G324	B:B:K280	1.74	No	No	0	9	1
890	R:R:C145	R:R:S141	1.72	No	No	0	6	2
891	A:A:G27	B:B:L55	1.71	No	No	0	5	6
892	A:A:G352	A:A:L353	1.71	Yes	No	0	8	7
893	A:A:G352	R:R:L438	1.71	Yes	No	0	8	7
894	B:B:C25	G:G:V30	1.71	No	No	0	3	8
895	R:R:G37	R:R:L36	1.71	No	No	0	9	8
896	R:R:C140	R:R:V136	1.71	No	No	0	4	7
897	A:A:G45	A:A:N269	1.7	No	Yes	0	9	9
898	A:A:G183	B:B:N119	1.7	No	No	0	9	9
899	B:B:A11	G:G:V16	1.7	No	No	0	5	7
900	B:B:G144	B:B:N119	1.7	No	No	0	8	9
901	B:B:A231	B:B:V276	1.7	No	No	0	5	6
902	B:B:A257	G:G:V30	1.7	No	No	0	7	8
903	B:B:A287	B:B:V276	1.7	No	No	0	6	6
904	R:R:G42	R:R:N41	1.7	No	Yes	0	6	9
905	A:A:C325	A:A:T327	1.69	No	No	0	7	8
906	R:R:A48	R:R:T58	1.68	No	No	0	7	8
907	R:R:M414	R:R:P405	1.68	No	No	0	2	4
908	B:B:K301	B:B:P39	1.67	No	No	0	5	1
909	R:R:L38	R:R:P39	1.64	Yes	No	0	7	7
910	R:R:C140	R:R:I59	1.64	No	No	0	4	6
911	A:A:S44	A:A:S47	1.63	No	No	0	9	9
912	R:R:S371	R:R:S373	1.63	No	No	0	7	4
913	A:A:I19	B:B:A92	1.62	No	No	0	9	6
914	B:B:A248	B:B:I269	1.62	No	No	0	5	4
915	R:R:A426	R:R:I29	1.62	No	No	0	8	7
916	B:B:D38	B:B:P39	1.61	No	No	0	1	1
917	B:B:S207	B:B:T223	1.6	No	No	0	5	2
918	R:R:V342	R:R:V343	1.6	No	No	0	6	4
919	R:R:V381	R:R:V382	1.6	No	No	0	7	8
920	R:R:V381	R:R:V385	1.6	No	No	0	7	7
921	A:A:T182	A:A:V185	1.59	No	No	0	7	5
922	A:A:T187	A:A:V185	1.59	No	No	0	6	5
923	R:R:T339	R:R:V343	1.59	No	No	0	8	4
924	B:B:A11	G:G:L15	1.58	No	No	0	5	2
925	B:B:L30	G:G:A34	1.58	No	No	0	5	6
926	B:B:A299	B:B:L300	1.58	No	Yes	0	5	6
927	G:G:A45	G:G:L51	1.58	No	Yes	0	4	6
928	R:R:C71	R:R:N105	1.57	No	No	0	8	9
929	R:R:T403	R:R:T407	1.57	Yes	No	0	2	7
930	A:A:A12	B:B:N88	1.56	No	Yes	0	4	7
931	A:A:C305	A:A:D309	1.56	No	No	0	3	4
932	B:B:C271	B:B:D291	1.56	No	No	0	5	8
933	R:R:I353	R:R:S357	1.55	No	No	0	5	6
934	G:G:A35	G:G:D36	1.54	No	No	0	2	5
935	R:R:I24	R:R:V28	1.54	No	No	0	7	6
936	R:R:I338	R:R:V342	1.54	No	No	0	6	6
937	R:R:I351	R:R:V350	1.54	No	No	0	6	4
938	R:R:K370	R:R:S371	1.53	No	No	0	7	7
939	R:R:I359	R:R:T375	1.52	No	No	0	9	7
940	R:R:K374	R:R:V378	1.52	No	No	0	9	8
941	A:A:K330	A:A:T329	1.5	No	No	0	4	9
942	B:B:L4	G:G:S8	1.5	No	No	0	4	4
943	R:R:G86	R:R:R171	1.5	No	Yes	0	7	1
944	R:R:G366	R:R:R365	1.5	No	No	0	2	4
945	A:A:L38	A:A:V50	1.49	No	No	0	8	6
946	A:A:N294	A:A:S293	1.49	No	No	0	3	3
947	B:B:L14	G:G:V16	1.49	Yes	No	0	8	7
948	A:A:V13	B:B:N88	1.48	No	Yes	0	3	7
949	A:A:N241	A:A:V233	1.48	No	No	0	9	5
950	A:A:C325	A:A:H322	1.47	No	Yes	0	7	9
951	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
952	R:R:L45	R:R:T65	1.47	No	No	0	8	9
953	A:A:D9	A:A:V13	1.46	No	No	0	4	3
954	B:B:N132	B:B:T128	1.46	No	Yes	0	3	3
955	B:B:D322	B:B:T65	1.45	No	No	0	1	1
956	A:A:K248	A:A:M240	1.44	No	No	0	5	6
957	B:B:M217	G:G:M21	1.44	No	No	0	3	1
958	G:G:K29	G:G:K32	1.44	No	No	0	4	5
959	R:R:E20	R:R:V23	1.43	No	No	0	4	4
960	B:B:E260	B:B:T263	1.41	Yes	No	0	6	1
961	A:A:P288	A:A:Y287	1.39	No	Yes	0	5	7
962	B:B:H54	B:B:S334	1.39	Yes	No	0	9	4
963	B:B:A208	B:B:F222	1.39	No	Yes	2	6	8
964	B:B:A208	B:B:F241	1.39	No	Yes	2	6	6
965	R:R:A446	R:R:F442	1.39	No	Yes	0	8	9
966	B:B:N35	B:B:N36	1.36	No	No	0	1	1
967	A:A:E14	A:A:K17	1.35	No	No	0	3	4
968	B:B:K280	G:G:E47	1.35	No	No	0	1	3
969	B:B:L14	B:B:Q17	1.33	Yes	No	0	8	4
970	R:R:R377	R:R:S373	1.32	No	No	0	5	4
971	A:A:H244	A:A:K248	1.31	No	No	0	4	5
972	B:B:D153	B:B:Q156	1.31	No	No	0	5	5
973	R:R:F111	R:R:V149	1.31	Yes	No	0	8	4
974	A:A:D237	A:A:E238	1.3	No	No	0	8	4
975	B:B:E12	B:B:Q9	1.27	No	No	0	4	3
976	B:B:D267	B:B:H266	1.26	No	No	0	3	4
977	R:R:F77	R:R:I98	1.26	No	Yes	0	8	8
978	R:R:I163	R:R:R92	1.25	No	No	0	6	1
979	R:R:S415	R:R:W416	1.24	No	Yes	0	5	7
980	A:A:N22	A:A:R21	1.21	No	No	0	4	4
981	B:B:F292	B:B:N293	1.21	No	No	0	4	5
982	B:B:F292	B:B:N313	1.21	No	No	0	4	7
983	B:B:E130	B:B:R129	1.16	No	No	0	3	3
984	A:A:E297	A:A:Y296	1.12	No	Yes	0	4	4
985	B:B:R46	B:B:R48	1.07	No	Yes	0	5	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:V34	3.855	4	5	5
2	A:A:L37	8.6675	4	1	9
3	A:A:I49	5.205	4	3	7
4	A:A:Q52	4.425	4	3	9
5	A:A:F191	9.1575	4	5	5
6	A:A:L194	6.555	4	5	4
7	A:A:K197	7.92	4	1	6
8	A:A:M198	3.7825	4	0	7
9	A:A:F199	5.982	5	1	5
10	A:A:Q204	6.6025	4	1	9
11	A:A:K210	5.85	6	1	9
12	A:A:W211	6.20333	6	1	9
13	A:A:H213	6.97	4	11	8
14	A:A:F215	6.93	6	1	9
15	A:A:I221	6.525	4	1	8
16	A:A:F223	7.24	5	0	9
17	A:A:V225	4.845	4	0	7
18	A:A:Y230	5.90833	6	12	8
19	A:A:F250	8.08	4	0	9
20	A:A:W258	9.20167	6	11	5
21	A:A:F259	5.6325	4	1	9
22	A:A:I265	3.7875	4	3	8
23	A:A:F267	4.308	5	3	9
24	A:A:N269	5.53	4	3	9
25	A:A:K270	5.6625	4	17	9
26	A:A:F274	7.078	5	12	9
27	A:A:Y287	5.94833	6	8	7
28	A:A:Y290	9.8875	4	8	7
29	A:A:Y296	4.805	4	0	4
30	A:A:Y302	10.1475	4	8	6
31	A:A:N311	5.04	4	18	8
32	A:A:Y320	7.35857	7	3	7
33	A:A:H322	8.1475	4	3	9
34	A:A:F323	3.5275	4	0	4
35	A:A:T324	5.8425	4	3	9
36	A:A:F334	8.3025	4	3	3
37	A:A:F336	5.84667	6	5	8
38	A:A:V339	3.2975	4	5	8
39	A:A:I344	3.95	4	5	6
40	A:A:G352	1.8175	4	0	8
41	A:A:F354	9.1225	4	0	5
42	B:B:L14	3.8375	4	0	8
43	B:B:V40	3.05	5	14	3
44	B:B:R48	6.9225	4	4	7
45	B:B:H54	7.17143	7	10	9
46	B:B:Y59	10.546	5	11	8
47	B:B:W63	7.21667	6	4	7
48	B:B:S74	5.93	4	10	9
49	B:B:D76	5.5925	4	10	9
50	B:B:I80	9.2275	4	10	8
51	B:B:W82	12.6425	4	10	9
52	B:B:N88	5.9125	4	0	7
53	B:B:K89	6.58833	6	10	9
54	B:B:L95	6.09	4	7	8
55	B:B:W99	7.84	7	1	9
56	B:B:Y105	3.91	5	0	6
57	B:B:Y111	5.2775	4	0	4
58	B:B:Y124	6.382	5	7	6
59	B:B:T128	2.93	4	0	3
60	B:B:V133	4.65	4	7	4
61	B:B:Y145	7.06833	6	1	8
62	B:B:L146	4.42	5	1	7
63	B:B:F151	5.248	5	0	9
64	B:B:L152	3.656	5	0	3
65	B:B:S161	6.325	4	1	9
66	B:B:W169	11.4175	4	1	8
67	B:B:F180	7.66	5	24	7
68	B:B:D186	6.235	4	1	9
69	B:B:V187	5.0475	4	0	9
70	B:B:M188	5.2075	4	1	8
71	B:B:L190	3.2	4	0	5
72	B:B:F199	5.965	4	24	9
73	B:B:V200	6.9275	4	2	6
74	B:B:C204	5.9125	4	1	7
75	B:B:W211	8.834	5	24	8
76	B:B:R219	7.7575	4	15	5
77	B:B:F222	7.975	4	2	8
78	B:B:H225	11.68	5	2	9
79	B:B:D228	7.2225	4	1	9
80	B:B:I229	5.07	4	2	7
81	B:B:I232	5.55	4	2	8
82	B:B:F234	5.17333	6	2	5
83	B:B:F235	4.84333	6	13	6
84	B:B:P236	5.6675	4	13	7
85	B:B:F241	5.49833	6	2	6
86	B:B:D246	6.545	4	1	9
87	B:B:R251	7.42429	7	2	8
88	B:B:F253	7.06667	6	2	6
89	B:B:D254	3.7525	4	0	9
90	B:B:R256	6.335	4	0	9
91	B:B:E260	4.4925	4	2	6
92	B:B:M262	5.4625	4	20	4
93	B:B:Y264	5.428	5	20	5
94	B:B:F278	6.552	5	13	7
95	B:B:L284	4.074	5	14	5
96	B:B:Y289	7.506	5	0	7
97	B:B:D290	7.465	4	0	6
98	B:B:L300	3.95	5	21	6
99	B:B:H311	6.995	4	9	9
100	B:B:L318	4.4725	4	0	6
101	B:B:T329	5.5325	4	0	8
102	B:B:W332	10.1286	7	11	9
103	B:B:D333	9.415	4	9	9
104	B:B:W339	7.786	5	22	9
105	B:B:N340	7.96	4	4	9
106	G:G:Y40	8.6075	4	13	6
107	G:G:D48	6.1	5	0	9
108	G:G:L51	3.122	5	14	6
109	G:G:N59	5.882	5	4	9
110	G:G:P60	7.0275	4	4	9
111	G:G:F61	5.46	8	4	8
112	G:G:R62	6.5925	4	0	7
113	R:R:L38	4.6175	4	6	7
114	R:R:N41	5.30333	6	6	9
115	R:R:W46	5.5675	4	9	6
116	R:R:W60	5.11833	6	0	8
117	R:R:H63	7.2875	4	0	8
118	R:R:D68	7.02167	6	6	9
119	R:R:L75	5.965	4	27	9
120	R:R:W88	9.6525	4	28	9
121	R:R:Y90	6.0425	4	28	7
122	R:R:K96	7.435	4	29	8
123	R:R:I98	4.105	4	0	8
124	R:R:I102	4.5625	4	0	8
125	R:R:F107	7.1575	4	0	8
126	R:R:F111	4.6875	4	0	8
127	R:R:R120	7.76	4	0	9
128	R:R:R134	4.5175	4	0	9
129	R:R:R161	8.125	4	0	8
130	R:R:H169	12.0675	4	16	3
131	R:R:R171	7.145	4	16	1
132	R:R:P348	3.5925	4	0	9
133	R:R:Y356	4.1275	4	0	9
134	R:R:F368	9.3925	4	3	5
135	R:R:W390	9.135	4	0	9
136	R:R:T403	3.795	4	0	2
137	R:R:W416	3.65	6	0	7
138	R:R:I421	3.465	4	0	4
139	R:R:Y435	4.748	5	6	9
140	R:R:F442	4.466	5	0	9
141	R:R:K445	4.2625	4	9	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:I19	B:B:K89	57.6369	8.72	No	Yes	0	9	9
2	A:A:I19	A:A:R15	56.991	6.26	No	No	0	9	5
3	A:A:R15	B:B:H91	56.8791	3.39	No	No	0	5	5
4	B:B:H54	B:B:I80	30.0446	13.26	Yes	Yes	10	9	8
5	B:B:I80	B:B:K89	29.8048	4.36	Yes	Yes	10	8	9
6	B:B:H54	B:B:W82	30.2323	3.17	Yes	Yes	10	9	9
7	B:B:K89	B:B:W82	29.8727	11.6	Yes	Yes	10	9	9
8	B:B:H54	B:B:I58	60.4359	7.95	Yes	No	10	9	9
9	B:B:I58	B:B:S316	61.4844	3.1	No	No	0	9	9
10	B:B:S316	B:B:W332	71.4863	4.94	No	Yes	0	9	9
11	B:B:N313	B:B:W332	88.2859	6.78	No	Yes	0	7	9
12	B:B:N313	B:B:S331	93.8925	2.98	No	No	0	7	9
13	B:B:D333	B:B:S331	90.2594	10.31	Yes	No	9	9	9
14	B:B:D312	B:B:D333	100	6.65	No	Yes	9	5	9
15	B:B:D312	R:R:K445	99.5437	5.53	No	Yes	9	5	7
16	R:R:K445	R:R:V47	98.4465	3.04	Yes	No	0	7	8
17	R:R:F442	R:R:V47	97.4619	6.55	Yes	No	0	9	8
18	R:R:F442	R:R:V44	96.268	9.18	Yes	No	0	9	9
19	R:R:T65	R:R:V44	96.0677	7.93	No	No	0	9	9
20	R:R:N41	R:R:T65	95.6661	5.85	Yes	No	0	9	9
21	R:R:D68	R:R:N41	90.6667	6.73	Yes	Yes	6	9	9
22	R:R:D68	R:R:L64	80.8195	9.5	Yes	No	6	9	9
23	R:R:L64	R:R:Y435	80.3154	3.52	No	Yes	6	9	9
24	R:R:R120	R:R:Y435	78.0365	8.23	Yes	Yes	0	9	9
25	R:R:I116	R:R:R120	75.2066	7.52	No	Yes	0	9	9
26	R:R:I116	R:R:W60	74.9684	7.05	No	Yes	0	9	8
27	R:R:I142	R:R:W60	35.5846	4.7	No	Yes	0	5	8
28	B:B:W332	B:B:Y59	39.0242	18.33	Yes	Yes	11	9	8
29	B:B:Q75	B:B:Y59	39.2144	13.53	No	Yes	0	9	8
30	B:B:Q75	B:B:W99	39.45	5.48	No	Yes	0	9	9
31	R:R:D119	R:R:W60	39.3255	3.35	No	Yes	0	9	8
32	R:R:D119	R:R:R134	39.0368	3.57	No	Yes	0	9	9
33	A:A:N347	R:R:R134	38.504	3.62	No	Yes	0	8	9
34	A:A:I343	A:A:N347	37.9231	4.25	No	No	0	7	8
35	A:A:I343	A:A:V339	37.3408	3.07	No	Yes	0	7	8
36	A:A:L36	A:A:V339	17.5819	2.98	No	Yes	5	7	8
37	A:A:L36	A:A:M198	17.4091	4.24	No	Yes	0	7	7
38	A:A:N256	A:A:W258	11.3371	9.04	No	Yes	0	8	5
39	A:A:F259	A:A:N256	11.172	4.83	Yes	No	0	9	8
40	A:A:F259	A:A:I221	10.7516	8.79	Yes	Yes	1	9	8
41	A:A:F215	B:B:W99	22.8021	11.02	Yes	Yes	1	9	9
42	A:A:I221	A:A:L39	10.2769	4.28	Yes	No	1	8	9
43	A:A:I253	A:A:L39	10.2137	4.28	No	No	0	8	9
44	A:A:I253	A:A:L249	10.0836	4.28	No	No	0	8	9
45	A:A:F223	A:A:L249	31.6009	4.87	Yes	No	0	9	9
46	A:A:F215	A:A:W211	22.51	5.01	Yes	Yes	1	9	9
47	A:A:R208	A:A:W211	22.2571	6	No	Yes	0	9	9
48	A:A:L249	A:A:R208	21.9299	4.86	No	No	0	9	9
49	B:B:L117	B:B:W99	22.1462	10.25	No	Yes	0	9	9
50	A:A:W211	B:B:L117	22.012	4.56	Yes	No	0	9	9
51	A:A:F223	A:A:V225	11.2832	3.93	Yes	Yes	0	9	7
52	A:A:I222	A:A:M198	15.0397	2.92	No	Yes	0	7	7
53	A:A:F267	A:A:I222	14.7259	5.02	Yes	No	0	9	7
54	A:A:F336	A:A:L194	17.1707	4.87	Yes	Yes	5	8	4
55	A:A:W211	B:B:Y145	21.1332	7.72	Yes	Yes	1	9	8
56	A:A:F223	A:A:L266	10.5617	4.87	Yes	No	0	9	9
57	B:B:R314	B:B:W332	22.9433	15.99	No	Yes	11	8	9
58	A:A:F336	A:A:T340	12.0543	7.78	Yes	No	5	8	6
59	A:A:I344	A:A:T340	10.7708	3.04	Yes	No	5	6	6
60	B:B:H91	B:B:V90	28.4004	6.92	No	No	0	5	5
61	B:B:I81	B:B:V90	28.1378	6.14	No	No	0	7	5
62	B:B:I81	B:B:V71	27.8764	3.07	No	No	0	7	8
63	B:B:V71	B:B:Y105	27.3928	3.79	No	Yes	0	8	6
64	B:B:H62	B:B:Y105	61.0846	3.27	No	Yes	0	6	6
65	B:B:H62	B:B:R150	60.5978	5.64	No	No	0	6	6
66	B:B:C148	B:B:R150	60.1107	5.57	No	No	0	6	6
67	B:B:C148	B:B:L190	59.6231	3.17	No	Yes	0	6	5
68	B:B:F199	B:B:L190	52.0663	3.65	Yes	Yes	0	9	5
69	B:B:F199	B:B:W211	45.5653	9.02	Yes	Yes	24	9	8
70	B:B:C218	B:B:W211	43.8087	7.84	No	Yes	0	5	8
71	B:B:C218	B:B:K209	42.8089	4.85	No	No	0	5	6
72	B:B:K209	B:B:T221	42.3085	9.01	No	No	0	6	7
73	B:B:T221	G:G:E22	41.8077	4.23	No	No	0	7	9
74	G:G:E22	G:G:I25	41.3065	2.73	No	No	0	9	2
75	B:B:Q220	G:G:I25	40.8049	4.12	No	No	0	7	2
76	B:B:D258	B:B:Q220	13.687	11.75	No	No	0	7	7
77	B:B:D258	B:B:R22	12.112	13.1	No	No	19	7	6
78	B:B:I18	B:B:R22	11.5978	6.26	No	No	0	7	6
79	B:B:I18	G:G:L19	10.5509	2.85	No	No	0	7	9
80	B:B:H91	B:B:V133	28.7557	4.15	No	Yes	0	5	4
81	B:B:L126	B:B:V133	35.8077	2.98	No	Yes	0	5	4
82	B:B:L126	B:B:V112	35.5449	5.96	No	No	0	5	8
83	B:B:V112	B:B:Y105	35.2825	3.79	No	Yes	0	8	6
84	B:B:D290	B:B:R314	25.101	19.06	Yes	No	0	6	8
85	B:B:C271	B:B:D290	28.4273	3.11	No	Yes	0	5	6
86	B:B:C271	B:B:Y289	34.1122	4.03	No	Yes	0	5	7
87	B:B:W297	B:B:Y289	28.2624	9.65	No	Yes	0	8	7
88	B:B:W297	B:B:Y264	27.5059	7.72	No	Yes	0	8	5
89	B:B:L285	B:B:Y264	24.7543	3.52	No	Yes	0	6	5
90	B:B:F278	B:B:L285	23.9647	13.4	Yes	No	0	7	6
91	B:B:F235	B:B:F278	11.79	6.43	Yes	Yes	13	6	7
92	B:B:F235	G:G:Y40	10.5898	3.09	Yes	Yes	13	6	6
93	B:B:N237	G:G:Y40	18.7402	16.28	No	Yes	0	5	6
94	B:B:N237	B:B:N239	17.9295	8.17	No	No	0	5	2
95	B:B:N239	B:B:R256	17.1185	7.23	No	Yes	0	2	9
96	B:B:F278	B:B:P236	10.9769	4.33	Yes	Yes	13	7	7
97	B:B:P236	G:G:Y40	10.5801	4.17	Yes	Yes	13	7	6
98	B:B:H311	B:B:T329	13.4131	8.21	Yes	Yes	0	9	8
99	B:B:C317	B:B:S316	12.9727	3.44	No	No	0	7	9
100	B:B:C317	B:B:M61	12.4401	4.86	No	No	0	7	6
101	B:B:V135	B:B:Y124	10.229	3.79	No	Yes	7	4	6
102	B:B:E138	B:B:V135	10.3104	4.28	No	No	7	6	4
103	B:B:S97	B:B:W99	11.4106	3.71	No	Yes	0	8	9
104	B:B:E138	B:B:I120	10.6309	4.1	No	No	0	6	6
105	B:B:D118	B:B:I120	11.0893	8.4	No	No	0	9	6
106	B:B:G162	B:B:Y145	17.1355	5.79	No	Yes	1	9	8
107	B:B:G162	B:B:S161	16.8397	3.71	No	Yes	1	9	9
108	B:B:H142	B:B:S161	12.6634	9.76	No	Yes	1	9	9
109	B:B:H142	B:B:W169	12.364	12.7	No	Yes	1	9	8
110	B:B:L139	B:B:W169	10.9741	15.94	No	Yes	0	9	8
111	B:B:F222	B:B:Q220	27.1214	5.86	Yes	No	0	8	7
112	B:B:F222	B:B:F241	18.7831	7.5	Yes	Yes	2	8	6
113	B:B:D290	B:B:T274	10.7534	4.34	Yes	No	0	6	8
114	R:R:I142	R:R:I146	32.6279	2.94	No	No	0	5	8
115	R:R:F111	R:R:I146	32.3302	5.02	Yes	No	0	8	8
116	R:R:F107	R:R:F111	31.4348	9.65	Yes	Yes	0	8	8
117	R:R:F107	R:R:R340	26.6025	6.41	Yes	No	0	8	9
118	R:R:R340	R:R:Y393	26.2973	6.17	No	No	0	9	9
119	R:R:I421	R:R:Y393	17.2655	3.63	Yes	No	0	4	9
120	R:R:I421	R:R:S78	16.0176	3.1	Yes	No	0	4	8
121	R:R:I102	R:R:S78	15.6996	9.29	Yes	No	0	8	8
122	R:R:I102	R:R:I98	14.4242	2.94	Yes	Yes	0	8	8
123	R:R:I98	R:R:L94	13.1286	7.14	Yes	No	0	8	8
124	R:R:L94	R:R:W88	11.822	9.11	No	Yes	28	8	9
125	R:R:C95	R:R:W88	11.5327	5.22	No	Yes	0	9	9
126	R:R:C95	R:R:R161	10.886	4.18	No	Yes	0	9	8
127	B:B:D118	B:B:S97	11.2445	4.42	No	No	0	9	8
128	B:B:D333	B:B:H311	10.6998	7.56	Yes	Yes	9	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8HK3

PDB Summary
PDB	8HK3
Class	A
SubFamily	Peptide
Type	Complement Peptide
SubType	C3A
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	3.2
Date	2023-05-10
D.O.I.	10.1038/s41589-023-01339-w

Net Summary
I_min	2.96
Number of Linked Nodes	852
Number of Links	985
Number of Hubs	141
Number of Links mediated by Hubs	535
Number of Communities	29
Number of Nodes involved in Communities	201
Number of Links involved in Communities	271

Path Summary
Number Of Nodes in MetaPath	129
Number Of Links MetaPath	128
Number of Shortest Paths	940904
Length Of Smallest Path	3
Average Path Length	32.5896
Length of Longest Path	77
Minimum Path Strength	1.21
Average Path Strength	6.25132
Maximum Path Strength	19.06
Minimum Path Correlation	0.7
Average Path Correlation	0.977033
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.92308
Average % Of Corr. Nodes	44.7216
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.7246
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • protein localization • positive regulation of protein localization to cell periphery • regulation of localization • protein localization to cell periphery • cellular localization • regulation of protein localization • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • localization • regulation of cellular localization • regulation of protein localization to cell cortex • cellular macromolecule localization • macromolecule localization • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • cilium • plasma membrane bounded cell projection • ciliary basal body • cell projection • cytoskeletal protein binding • spectrin binding • protein-containing complex binding • protein binding • binding • enzyme binding • GTPase binding • phosphoric ester hydrolase activity • alkylglycerophosphoethanolamine phosphodiesterase activity • hydrolase activity, acting on ester bonds • phosphoric diester hydrolase activity • hydrolase activity • catalytic activity • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity, acting on acid anhydrides • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • positive regulation of cytosolic calcium ion concentration • biological regulation • regulation of biological quality • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • response to decreased oxygen levels • cellular response to stimulus • response to stimulus • cellular response to oxygen levels • cellular response to hypoxia • cellular response to decreased oxygen levels • cellular response to chemical stimulus • cellular response to stress • response to hypoxia • response to stress • response to chemical • response to oxygen levels • response to abiotic stimulus • cellular process • cell population proliferation • regulation of biological process • regulation of cellular process • signaling • phospholipase C-activating G protein-coupled receptor signaling pathway • cell communication • G protein-coupled receptor signaling pathway • signal transduction • muscle cell apoptotic process • striated muscle cell apoptotic process • apoptotic process • cell death • programmed cell death • cardiac muscle cell apoptotic process • photoreceptor inner segment • somatodendritic compartment • dendrite • dendritic tree • neuron projection • non-motile cilium • 9+0 non-motile cilium • photoreceptor outer segment • photoreceptor cell cilium • ciliary membrane • photoreceptor outer segment membrane • plasma membrane region • cell projection membrane • synapse • cell junction • cell body • complement component C3a receptor activity • molecular transducer activity • complement receptor activity • transmembrane signaling receptor activity • signaling receptor activity • immune receptor activity • opsonin receptor activity • complement component C5a receptor activity • G protein-coupled receptor activity • positive regulation of locomotion • regulation of cell motility • macrophage migration • positive regulation of chemotaxis • positive regulation of cell migration • taxis • cell migration • regulation of immune system process • regulation of mononuclear cell migration • positive regulation of immune system process • chemotaxis • regulation of leukocyte chemotaxis • regulation of leukocyte migration • positive regulation of macrophage migration • response to external stimulus • positive regulation of leukocyte chemotaxis • granulocyte migration • leukocyte migration • regulation of response to stimulus • regulation of locomotion • regulation of response to external stimulus • macrophage chemotaxis • positive regulation of biological process • positive regulation of response to stimulus • regulation of granulocyte chemotaxis • regulation of macrophage migration • positive regulation of response to external stimulus • positive regulation of cell motility • regulation of cell migration • myeloid leukocyte migration • positive regulation of mononuclear cell migration • cell motility • locomotion • positive regulation of cellular process • cell chemotaxis • regulation of macrophage chemotaxis • positive regulation of leukocyte migration • regulation of chemotaxis • immune system process • granulocyte chemotaxis • mononuclear cell migration • positive regulation of macrophage chemotaxis • leukocyte chemotaxis • positive regulation of macromolecule biosynthetic process • positive regulation of metabolic process • positive regulation of biosynthetic process • regulation of cytokine production • cytokine production • regulation of multicellular organismal process • positive regulation of macromolecule metabolic process • regulation of vascular endothelial growth factor production • regulation of biosynthetic process • regulation of macromolecule metabolic process • gene expression • macromolecule biosynthetic process • regulation of gene expression • vascular endothelial growth factor production • biosynthetic process • positive regulation of gene expression • positive regulation of multicellular organismal process • positive regulation of vascular endothelial growth factor production • regulation of macromolecule biosynthetic process • metabolic process • macromolecule metabolic process • positive regulation of cytokine production • regulation of metabolic process • regulation of developmental process • angiogenesis • regulation of vasculature development • positive regulation of developmental process • tube morphogenesis • regulation of anatomical structure morphogenesis • blood vessel development • regulation of multicellular organismal development • blood vessel morphogenesis • tube development • positive regulation of angiogenesis • vasculature development • circulatory system development • anatomical structure morphogenesis • positive regulation of vasculature development • regulation of angiogenesis • anatomical structure formation involved in morphogenesis • immune response-regulating cell surface receptor signaling pathway • complement receptor mediated signaling pathway • immune response-activating signaling pathway • immune response-regulating signaling pathway • positive regulation of immune response • cell surface receptor signaling pathway • immune response-activating cell surface receptor signaling pathway • immune response • regulation of immune response • activation of immune response • defense response • inflammatory response • positive regulation of neutrophil chemotaxis • neutrophil migration • positive regulation of granulocyte chemotaxis • regulation of neutrophil chemotaxis • regulation of neutrophil migration • neutrophil chemotaxis • positive regulation of neutrophil migration • intracellular signal transduction • calcium-mediated signaling • intracellular signaling cassette • circulatory system process • blood circulation • intracellular vesicle • specific granule membrane • cytoplasmic vesicle membrane • vesicle membrane • cytoplasmic vesicle • secretory granule • secretory vesicle • secretory granule membrane • specific granule • azurophil granule • primary lysosome • azurophil granule membrane • G-protein beta-subunit binding • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>8HK3_Chain_A L S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K S T I V K Q M K T G I V E T H F T F K D L H F K M F D V G A Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L A E D E E M N R M H E S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C S T D T K N V Q F V F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P54311
Sequence	>8HK3_Chain_B S E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P63212
Sequence	>8HK3_Chain_G S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R E Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q16581
Sequence	>8HK3_Chain_R W N E P P V I L S M V I L S L T F L L G L P G N G L V L W V A G L K M Q R T V N T I W F L H L T L A D L L C C L S L P F S L A H L A L Q G Q W P Y G R F L C K L I P S I I V L N M F A S V F L L T A I S L D R C L V V F K P I W C Q N H R N V G M A C S I C G C I W V V A F V M C I P V F V Y R E I F T T D N H N R C G Y K F P T P L V A I T I T R L V V G F L L P S V I M I A C Y S F I V F R M Q R G R F A K S Q S K T F R V A V V V V A V F L V C W T P Y H I F G V L S L L T D P E T P L G K T L M S W D H V C I A L A S A N S C F N P F L Y A L L G K D F R K K A R Q S I Q G I L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8J6D	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP141	-	Go/β1/γ2	3.1	2023-10-18	10.1016/j.cell.2023.09.020
	8J6D (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP141	-		3.1	2023-10-18	10.1016/j.cell.2023.09.020
	8I9A	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.57	2023-10-18	10.1016/j.cell.2023.09.020
	8I9A (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-		3.57	2023-10-18	10.1016/j.cell.2023.09.020
	8I9S	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Go/β1/γ2	3.26	2023-10-18	10.1016/j.cell.2023.09.020
	8I9S (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.26	2023-10-18	10.1016/j.cell.2023.09.020
	8I9L	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a anaphylatoxin	-	Go/β1/γ2	3.18	2023-10-18	10.1016/j.cell.2023.09.020
	8I9L (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a anaphylatoxin	-		3.18	2023-10-18	10.1016/j.cell.2023.09.020
	8I97	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Go/β1/γ2	3.1	2023-10-18	10.1016/j.cell.2023.09.020
	8I97 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.1	2023-10-18	10.1016/j.cell.2023.09.020
	8I95	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-	Go/β1/γ2	2.88	2023-10-18	10.1016/j.cell.2023.09.020
	8I95 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-		2.88	2023-10-18	10.1016/j.cell.2023.09.020
	8IA8	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	E7 peptide	-	Gi1/β1/γ2	2.86	2023-05-24	To be published
	8IA8 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	E7 peptide	-		2.86	2023-05-24	To be published
	8HK3 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.2	2023-05-10	10.1038/s41589-023-01339-w
	8HK2	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a anaphylatoxin	-	Gi1/β1/γ2	2.9	2023-05-10	10.1038/s41589-023-01339-w
	8HK2 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a anaphylatoxin	-		2.9	2023-05-10	10.1038/s41589-023-01339-w

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