psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F170	4.51	Yes	Yes	1	0	7
2	L:L:?1	R:R:S173	6.66	Yes	No	1	0	4
3	L:L:?1	R:R:F174	2.7	Yes	Yes	1	0	5
4	L:L:?1	R:R:F177	3.6	Yes	No	0	0	4
5	L:L:?1	R:R:F189	5.41	Yes	Yes	1	0	9
6	L:L:?1	R:R:K192	2.09	Yes	Yes	1	0	6
7	L:L:?1	R:R:L193	6.14	Yes	No	1	0	4
8	L:L:?1	R:R:V196	2.2	Yes	No	1	0	7
9	L:L:?1	R:R:T197	10.9	Yes	No	0	0	6
10	L:L:?1	R:R:F268	25.23	Yes	Yes	1	0	5
11	L:L:?1	R:R:L276	2.05	Yes	No	1	0	5
12	L:L:?1	R:R:W279	10.11	Yes	Yes	0	0	6
13	L:L:?1	R:R:S383	5.55	Yes	No	1	0	6
14	R:R:F108	R:R:M109	8.71	No	No	0	5	3
15	R:R:F108	R:R:V110	2.62	No	No	0	5	3
16	R:R:F177	R:R:M109	8.71	No	No	0	4	3
17	R:R:K373	R:R:V110	3.04	No	No	0	3	3
18	R:R:L111	R:R:Q116	5.32	No	No	0	4	4
19	R:R:H178	R:R:L111	5.14	No	No	0	4	4
20	R:R:N112	R:R:P113	11.4	No	No	4	6	2
21	R:R:N112	R:R:S114	2.98	No	No	4	6	5
22	R:R:N112	R:R:Q115	10.56	No	No	0	6	2
23	R:R:P113	R:R:S114	1.78	No	No	4	2	5
24	R:R:Q116	R:R:V179	4.3	No	No	0	4	4
25	R:R:F174	R:R:I119	3.77	Yes	No	0	5	5
26	R:R:F381	R:R:I119	5.02	No	No	0	4	5
27	R:R:L122	R:R:L126	4.15	No	No	0	5	6
28	R:R:L122	R:R:M384	2.83	No	Yes	0	5	5
29	R:R:S123	R:R:V171	4.85	No	No	0	7	7
30	R:R:M384	R:R:S123	3.07	Yes	No	0	5	7
31	R:R:F129	R:R:T125	5.19	No	No	0	4	4
32	R:R:L126	R:R:L387	2.77	No	Yes	0	6	7
33	R:R:G127	R:R:T130	1.82	No	Yes	5	6	7
34	R:R:G127	R:R:S167	1.86	No	No	5	6	7
35	R:R:G127	R:R:L387	1.71	No	Yes	0	6	7
36	R:R:N134	R:R:T130	4.39	No	Yes	0	9	7
37	R:R:S167	R:R:T130	3.2	No	Yes	5	7	7
38	R:R:S390	R:R:T130	9.59	No	Yes	0	9	7
39	R:R:T130	R:R:T391	6.28	Yes	No	0	7	7
40	R:R:L164	R:R:V131	4.47	No	No	0	7	6
41	R:R:N134	R:R:P394	4.89	No	No	0	9	9
42	R:R:P394	R:R:V137	1.77	No	No	0	9	9
43	R:R:I141	R:R:Y153	3.63	No	Yes	0	7	9
44	R:R:P151	R:R:R150	2.88	No	No	0	5	5
45	R:R:R150	R:R:Y153	12.35	No	Yes	6	5	9
46	R:R:D403	R:R:R150	9.53	No	No	6	6	5
47	R:R:P151	R:R:R230	7.21	No	No	0	5	1
48	R:R:D213	R:R:S152	4.42	Yes	No	0	9	8
49	R:R:I156	R:R:Y153	2.42	No	Yes	0	8	9
50	R:R:D403	R:R:Y153	3.45	No	Yes	6	6	9
51	R:R:L404	R:R:Y153	10.55	No	Yes	0	8	9
52	R:R:H154	R:R:V234	2.77	No	No	0	3	1
53	R:R:F155	R:R:L209	10.96	Yes	No	0	8	6
54	R:R:D213	R:R:F155	2.39	Yes	Yes	0	9	8
55	R:R:A236	R:R:F155	2.77	No	Yes	0	5	8
56	R:R:A160	R:R:G157	1.95	No	No	0	9	6
57	R:R:S158	R:R:S206	4.89	No	No	0	9	8
58	R:R:F237	R:R:S158	2.64	Yes	No	0	8	9
59	R:R:L159	R:R:S206	6.01	No	No	0	9	8
60	R:R:L159	R:R:Y397	3.52	No	Yes	0	9	9
61	R:R:A162	R:R:A202	1.79	No	No	2	8	7
62	R:R:A162	R:R:S203	1.71	No	No	0	8	9
63	R:R:A162	R:R:W241	2.59	No	Yes	2	8	9
64	R:R:D163	R:R:S390	11.78	No	No	0	9	9
65	R:R:G166	R:R:L165	1.71	No	No	0	8	6
66	R:R:G166	R:R:S199	3.71	No	No	0	8	7
67	R:R:F170	R:R:F174	4.29	Yes	Yes	1	7	5
68	R:R:F170	R:R:V196	3.93	Yes	No	1	7	7
69	R:R:F170	R:R:S383	5.28	Yes	No	1	7	6
70	R:R:F170	R:R:L387	2.44	Yes	Yes	0	7	7
71	R:R:L387	R:R:V171	4.47	Yes	No	0	7	7
72	R:R:K192	R:R:S173	9.18	Yes	No	1	6	4
73	R:R:F174	R:R:H178	10.18	Yes	No	0	5	4
74	R:R:A380	R:R:F174	2.77	No	Yes	0	4	5
75	R:R:F174	R:R:M384	2.49	Yes	Yes	0	5	5
76	R:R:I175	R:R:V179	3.07	No	No	0	5	4
77	R:R:D176	R:R:R182	17.87	No	No	0	3	4
78	R:R:D176	R:R:K192	2.77	No	Yes	0	3	6
79	R:R:F177	R:R:H178	10.18	No	No	0	4	4
80	R:R:D184	R:R:V188	11.69	No	No	0	2	5
81	R:R:R186	R:R:S185	9.22	No	No	0	3	7
82	R:R:N187	R:R:V188	4.43	No	No	0	1	5
83	R:R:F189	R:R:L190	2.44	Yes	No	0	9	5
84	R:R:F189	R:R:L193	2.44	Yes	No	1	9	4
85	R:R:F189	R:R:P269	5.78	Yes	No	0	9	3
86	R:R:I271	R:R:L193	4.28	No	No	0	3	4
87	R:R:G194	R:R:G195	2.11	No	No	0	6	4
88	R:R:A248	R:R:G194	1.95	No	No	0	7	6
89	R:R:F200	R:R:V196	2.62	No	No	0	7	7
90	R:R:A248	R:R:T197	3.36	No	No	0	7	6
91	R:R:A198	R:R:A248	1.79	No	No	0	5	7
92	R:R:C386	R:R:F200	8.38	No	No	0	7	7
93	R:R:A202	R:R:W241	7.78	No	Yes	2	7	9
94	R:R:L286	R:R:V204	4.47	Yes	No	0	8	7
95	R:R:V204	R:R:W356	4.9	No	Yes	0	7	8
96	R:R:G205	R:R:M240	1.75	No	Yes	0	5	6
97	R:R:G205	R:R:L286	1.71	No	Yes	0	5	8
98	R:R:M240	R:R:S206	4.6	Yes	No	0	6	8
99	R:R:L207	R:R:Y397	3.52	No	Yes	0	8	9
100	R:R:F208	R:R:L286	6.09	No	Yes	0	7	8
101	R:R:F208	R:R:F289	4.29	No	No	0	7	6
102	R:R:A211	R:R:A293	1.79	No	No	0	8	7
103	R:R:A211	R:R:Y294	4	No	Yes	0	8	9
104	R:R:D213	R:R:Y224	6.9	Yes	No	7	9	7
105	R:R:D213	R:R:V228	4.38	Yes	No	7	9	6
106	R:R:R214	R:R:Y294	4.12	No	Yes	0	9	9
107	R:R:H219	R:R:Y215	4.36	No	No	9	6	8
108	R:R:Y215	R:R:Y296	8.94	No	No	9	8	4
109	R:R:S217	R:R:Y224	5.09	No	No	0	8	7
110	R:R:I218	R:R:I297	4.42	No	No	0	9	9
111	R:R:I218	R:R:K300	2.91	No	No	0	9	5
112	R:R:H219	R:R:R220	6.77	No	No	0	6	5
113	R:R:H219	R:R:Y296	8.71	No	No	9	6	4
114	R:R:A223	R:R:R226	2.77	No	No	0	5	4
115	R:R:V228	R:R:Y224	3.79	No	No	7	6	7
116	R:R:P231	R:R:T229	10.49	No	No	0	4	8
117	R:R:K232	R:R:T229	4.5	No	No	0	5	8
118	R:R:F237	R:R:M240	2.49	Yes	Yes	2	8	6
119	R:R:F237	R:R:W241	2	Yes	Yes	2	8	9
120	R:R:M240	R:R:W241	6.98	Yes	Yes	2	6	9
121	R:R:F278	R:R:I247	3.77	No	No	0	6	5
122	R:R:P251	R:R:Y275	6.95	No	Yes	0	6	7
123	R:R:D266	R:R:E273	3.9	No	No	0	4	3
124	R:R:D266	R:R:D366	5.32	No	No	0	4	4
125	R:R:F268	R:R:I267	2.51	Yes	Yes	1	5	4
126	R:R:D366	R:R:I267	11.2	No	Yes	0	4	4
127	R:R:I267	R:R:K376	2.91	Yes	No	0	4	2
128	R:R:F379	R:R:I267	7.54	Yes	Yes	1	4	4
129	R:R:F268	R:R:I271	2.51	Yes	No	0	5	3
130	R:R:F268	R:R:L276	2.44	Yes	No	1	5	5
131	R:R:F268	R:R:F379	3.22	Yes	Yes	1	5	4
132	R:R:H270	R:R:P269	4.58	No	No	0	3	3
133	R:R:I271	R:R:Y275	3.63	No	Yes	0	3	7
134	R:R:D272	R:R:T274	2.89	No	No	0	5	5
135	R:R:D272	R:R:Y275	3.45	No	Yes	0	5	7
136	R:R:M277	R:R:V367	4.56	No	No	0	4	4
137	R:R:T283	R:R:W279	8.49	No	Yes	0	8	6
138	R:R:M363	R:R:W279	3.49	No	Yes	0	6	6
139	R:R:I280	R:R:M363	4.37	No	No	0	5	6
140	R:R:G281	R:R:S284	1.86	No	No	0	3	5
141	R:R:S284	R:R:V285	3.23	No	No	0	5	6
142	R:R:L287	R:R:L352	2.77	No	No	0	6	9
143	R:R:L287	R:R:W356	2.28	No	Yes	0	6	8
144	R:R:I290	R:R:Y294	2.42	No	Yes	0	8	9
145	R:R:L349	R:R:V291	2.98	No	No	0	8	5
146	R:R:L345	R:R:Y294	10.55	No	Yes	0	8	9
147	R:R:L349	R:R:Y294	3.52	No	Yes	0	8	9
148	R:R:K300	R:R:Y296	4.78	No	No	0	5	4
149	R:R:I297	R:R:L345	2.85	No	No	0	9	8
150	R:R:L298	R:R:L345	2.77	No	No	0	6	8
151	R:R:D338	R:R:H302	16.39	No	No	0	7	5
152	R:R:H304	R:R:M308	5.25	No	No	0	7	7
153	R:R:A305	R:R:D338	4.63	No	No	0	5	7
154	R:R:R307	R:R:R311	7.46	No	No	0	4	5
155	R:R:D338	R:R:I339	2.8	No	No	0	7	5
156	R:R:R400	R:R:T344	5.17	No	No	0	7	8
157	R:R:I348	R:R:L349	2.85	No	No	0	8	8
158	R:R:I348	R:R:I396	2.94	No	Yes	8	8	9
159	R:R:I348	R:R:Y397	3.63	No	Yes	8	8	9
160	R:R:I396	R:R:V351	3.07	Yes	No	0	9	6
161	R:R:C355	R:R:L388	4.76	No	No	0	8	5
162	R:R:C355	R:R:N389	7.87	No	No	0	8	9
163	R:R:L360	R:R:W356	3.42	No	Yes	0	7	8
164	R:R:N389	R:R:W356	4.52	No	Yes	0	9	8
165	R:R:G357	R:R:P358	4.06	No	No	0	5	9
166	R:R:C382	R:R:P358	1.88	No	No	0	5	9
167	R:R:L385	R:R:P358	4.93	No	No	0	7	9
168	R:R:L359	R:R:L360	2.77	No	No	0	7	7
169	R:R:L359	R:R:L385	2.77	No	No	0	7	7
170	R:R:F379	R:R:I362	3.77	Yes	No	0	4	4
171	R:R:C382	R:R:I362	3.27	No	No	0	5	4
172	R:R:F379	R:R:M363	2.49	Yes	No	0	4	6
173	R:R:M371	R:R:Y365	7.18	Yes	No	3	1	4
174	R:R:N372	R:R:Y365	4.65	No	No	3	1	4
175	R:R:I375	R:R:Y365	8.46	No	No	3	3	4
176	R:R:D366	R:R:M371	5.54	No	Yes	0	4	1
177	R:R:G369	R:R:K370	1.74	No	No	0	3	1
178	R:R:I375	R:R:M371	8.75	No	Yes	3	3	1
179	R:R:K376	R:R:M371	2.88	No	Yes	0	2	1
180	R:R:I375	R:R:N372	4.25	No	No	3	3	1
181	R:R:L387	R:R:M384	5.65	Yes	Yes	0	7	5
182	R:R:N389	R:R:N393	5.45	No	No	0	9	9
183	R:R:I395	R:R:V392	3.07	No	No	0	6	6
184	R:R:I396	R:R:V392	3.07	Yes	No	0	9	6
185	R:R:I396	R:R:Y397	3.63	Yes	Yes	8	9	9
186	R:R:A398	R:R:V137	1.7	No	No	0	7	9
187	R:R:A244	R:R:T201	1.68	No	No	0	8	6
188	R:R:L250	R:R:P251	1.64	No	No	0	5	6
189	R:R:L253	R:R:P251	1.64	No	No	0	5	6
190	R:R:S185	R:R:V188	1.62	No	No	0	7	5
191	R:R:A198	R:R:I245	1.62	No	No	0	5	4
192	R:R:A301	R:R:M337	1.61	No	No	0	8	6
193	R:R:A305	R:R:M337	1.61	No	No	0	5	6
194	R:R:V131	R:R:V168	1.6	No	No	0	6	4
195	R:R:A342	R:R:L298	1.58	No	No	0	7	6
196	R:R:A301	R:R:L341	1.58	No	No	0	8	8
197	R:R:A398	R:R:L404	1.58	No	No	0	7	8
198	R:R:E133	R:R:P394	1.57	No	No	0	8	9
199	R:R:I169	R:R:S173	1.55	No	No	0	5	4
200	R:R:I218	R:R:S217	1.55	No	No	0	9	8
201	R:R:I227	R:R:V228	1.54	No	No	0	4	6
202	R:R:I245	R:R:V249	1.54	No	No	0	4	5
203	R:R:I354	R:R:V350	1.54	No	No	0	5	6
204	R:R:M411	R:R:V140	1.52	No	No	0	5	8
205	R:R:I243	R:R:T242	1.52	No	No	0	5	4
206	R:R:M295	R:R:V291	1.52	No	No	0	3	5
207	R:R:L165	R:R:V161	1.49	No	No	0	6	6
208	R:R:L276	R:R:V367	1.49	No	No	0	5	4
209	R:R:L286	R:R:V285	1.49	Yes	No	0	8	6
210	R:R:L347	R:R:V350	1.49	No	No	0	7	6
211	R:R:L126	R:R:T125	1.47	No	No	0	6	4
212	R:R:L239	R:R:T242	1.47	No	No	0	3	4
213	R:R:I353	R:R:I354	1.47	No	No	0	6	5
214	R:R:P221	R:R:R220	1.44	No	No	0	8	5
215	R:R:P231	R:R:R230	1.44	No	No	0	4	1
216	R:R:I141	R:R:L138	1.43	No	No	0	7	7
217	R:R:I212	R:R:L209	1.43	No	No	0	7	6
218	R:R:I297	R:R:L341	1.43	No	No	0	9	8
219	R:R:K373	R:R:L374	1.41	No	No	0	3	4
220	R:R:C149	R:R:R148	1.39	No	No	0	7	8
221	R:R:D403	R:R:K402	1.38	No	No	0	6	5
222	R:R:R307	R:R:S303	1.32	No	No	0	4	5
223	R:R:H181	R:R:M109	1.31	No	No	0	3	3
224	R:R:F408	R:R:V140	1.31	No	No	0	7	8
225	R:R:F237	R:R:V234	1.31	Yes	No	0	8	1
226	R:R:H304	R:R:M337	1.31	No	No	0	7	6
227	R:R:F368	R:R:V364	1.31	No	No	0	5	6
228	R:R:F129	R:R:T128	1.3	No	No	0	4	5
229	R:R:F155	R:R:T210	1.3	Yes	No	0	8	9
230	R:R:F191	R:R:K192	1.24	No	Yes	0	5	6
231	R:R:M308	R:R:R307	1.24	No	No	0	7	4
232	R:R:K402	R:R:R405	1.24	No	No	0	5	8
233	R:R:I175	R:R:Y172	1.21	No	No	0	5	7
234	R:R:T201	R:R:W279	1.21	No	Yes	0	6	6
235	R:R:I216	R:R:Y215	1.21	No	No	0	5	8
236	R:R:I247	R:R:Y275	1.21	No	Yes	0	5	7
237	R:R:D184	R:R:R182	1.19	No	No	0	2	4
238	R:R:D184	R:R:F189	1.19	No	Yes	0	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	6.70385	13	1	0
2	R:R:T130	5.056	5	5	7
3	R:R:Y153	6.48	5	6	9
4	R:R:F155	4.355	4	0	8
5	R:R:F170	4.09	5	1	7
6	R:R:F174	4.36667	6	1	5
7	R:R:F189	3.452	5	1	9
8	R:R:K192	3.82	4	1	6
9	R:R:D213	4.5225	4	7	9
10	R:R:F237	2.11	4	2	8
11	R:R:M240	3.955	4	2	6
12	R:R:W241	4.8375	4	2	9
13	R:R:I267	6.04	4	1	4
14	R:R:F268	7.182	5	1	5
15	R:R:Y275	3.81	4	0	7
16	R:R:W279	5.825	4	0	6
17	R:R:L286	3.44	4	0	8
18	R:R:Y294	4.922	5	0	9
19	R:R:W356	3.78	4	0	8
20	R:R:M371	6.0875	4	3	1
21	R:R:F379	4.255	4	1	4
22	R:R:M384	3.51	4	0	5
23	R:R:L387	3.408	5	0	7
24	R:R:I396	3.1775	4	8	9
25	R:R:Y397	3.575	4	8	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F177	22.3434	3.6	Yes	No	0	0	4
2	R:R:F177	R:R:M109	12.2626	8.71	No	No	0	4	3
3	L:L:?1	R:R:F174	19.7818	2.7	Yes	Yes	1	0	5
4	R:R:F174	R:R:H178	14.2593	10.18	Yes	No	0	5	4
5	R:R:H178	R:R:L111	19.5188	5.14	No	No	0	4	4
6	R:R:F177	R:R:H178	10.0516	10.18	No	No	0	4	4
7	R:R:L111	R:R:Q116	15.6521	5.32	No	No	0	4	4
8	R:R:Q116	R:R:V179	11.7659	4.3	No	No	0	4	4
9	L:L:?1	R:R:F170	49.2841	4.51	Yes	Yes	1	0	7
10	R:R:F170	R:R:L387	52.6541	2.44	Yes	Yes	0	7	7
11	R:R:G127	R:R:L387	47.492	1.71	No	Yes	0	6	7
12	R:R:G127	R:R:T130	43.8979	1.82	No	Yes	5	6	7
13	R:R:N134	R:R:T130	37.1481	4.39	No	Yes	0	9	7
14	R:R:N134	R:R:P394	35.356	4.89	No	No	0	9	9
15	R:R:P394	R:R:V137	31.7133	1.77	No	No	0	9	9
16	R:R:A398	R:R:V137	29.8627	1.7	No	No	0	7	9
17	R:R:A398	R:R:L404	27.9926	1.58	No	No	0	7	8
18	R:R:L404	R:R:Y153	26.0836	10.55	No	Yes	0	8	9
19	R:R:R150	R:R:Y153	12.3795	12.35	No	Yes	6	5	9
20	R:R:P151	R:R:R150	10.5094	2.88	No	No	0	5	5
21	L:L:?1	R:R:F268	92.2178	25.23	Yes	Yes	1	0	5
22	R:R:F268	R:R:F379	83.072	3.22	Yes	Yes	1	5	4
23	R:R:F379	R:R:I362	100	3.77	Yes	No	0	4	4
24	R:R:C382	R:R:I362	99.6104	3.27	No	No	0	5	4
25	R:R:C382	R:R:P358	99.2013	1.88	No	No	0	5	9
26	R:R:L385	R:R:P358	98.3247	4.93	No	No	0	7	9
27	R:R:L359	R:R:L385	97.8572	2.77	No	No	0	7	7
28	R:R:L359	R:R:L360	97.3702	2.77	No	No	0	7	7
29	R:R:L360	R:R:W356	96.8637	3.42	No	Yes	0	7	8
30	R:R:V204	R:R:W356	92.773	4.9	No	Yes	0	7	8
31	R:R:L286	R:R:V204	92.1106	4.47	Yes	No	0	8	7
32	R:R:G205	R:R:L286	87.7277	1.71	No	Yes	0	5	8
33	R:R:G205	R:R:M240	86.929	1.75	No	Yes	0	5	6
34	R:R:M240	R:R:S206	78.2799	4.6	Yes	No	0	6	8
35	R:R:L159	R:R:S206	77.8514	6.01	No	No	0	9	8
36	R:R:L159	R:R:Y397	76.7313	3.52	No	Yes	0	9	9
37	R:R:I348	R:R:Y397	68.3744	3.63	No	Yes	8	8	9
38	R:R:I348	R:R:L349	68.8614	2.85	No	No	0	8	8
39	R:R:L349	R:R:Y294	65.17	3.52	No	Yes	0	8	9
40	R:R:L345	R:R:Y294	58.9559	10.55	No	Yes	0	8	9
41	R:R:I297	R:R:L345	54.7482	2.85	No	No	0	9	8
42	R:R:I218	R:R:I297	34.6839	4.42	No	No	0	9	9
43	R:R:I218	R:R:S217	20.9019	1.55	No	No	0	9	8
44	R:R:S217	R:R:Y224	19.0708	5.09	No	No	0	8	7
45	R:R:D213	R:R:Y224	13.295	6.9	Yes	No	7	9	7
46	L:L:?1	R:R:F189	17.5709	5.41	Yes	Yes	1	0	9
47	R:R:D184	R:R:F189	11.5613	1.19	No	Yes	0	2	9
48	R:R:F268	R:R:I271	16.9183	2.51	Yes	No	0	5	3
49	L:L:?1	R:R:T197	13.8892	10.9	Yes	No	0	0	6
50	R:R:A248	R:R:T197	12.2041	3.36	No	No	0	7	6
51	R:R:I218	R:R:K300	13.7138	2.91	No	No	0	9	5
52	R:R:K300	R:R:Y296	11.8438	4.78	No	No	0	5	4
53	R:R:I271	R:R:Y275	21.1357	3.63	No	Yes	0	3	7
54	R:R:F268	R:R:I267	15.3307	2.51	Yes	Yes	1	5	4
55	R:R:D366	R:R:I267	15.3696	11.2	No	Yes	0	4	4
56	R:R:I267	R:R:K376	11.5321	2.91	Yes	No	0	4	2
57	R:R:I297	R:R:L341	22.957	1.43	No	No	0	9	8
58	R:R:A301	R:R:L341	21.1844	1.58	No	No	0	8	8
59	R:R:A301	R:R:M337	19.3435	1.61	No	No	0	8	6
60	R:R:F379	R:R:I267	13.2074	7.54	Yes	Yes	1	4	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:F170	4.51	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:S173	6.66	1	Yes	No	0	4	0	1
L:L:?1	R:R:F174	2.7	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:F177	3.6	1	Yes	No	0	4	0	1
L:L:?1	R:R:F189	5.41	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:K192	2.09	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:L193	6.14	1	Yes	No	0	4	0	1
L:L:?1	R:R:V196	2.2	1	Yes	No	0	7	0	1
L:L:?1	R:R:T197	10.9	1	Yes	No	0	6	0	1
L:L:?1	R:R:F268	25.23	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L276	2.05	1	Yes	No	0	5	0	1
L:L:?1	R:R:W279	10.11	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:S383	5.55	1	Yes	No	0	6	0	1
R:R:F177	R:R:M109	8.71	0	No	No	4	3	1	2
R:R:F174	R:R:I119	3.77	1	Yes	No	5	5	1	2
R:R:F170	R:R:F174	4.29	1	Yes	Yes	7	5	1	1
R:R:F170	R:R:V196	3.93	1	Yes	No	7	7	1	1
R:R:F170	R:R:S383	5.28	1	Yes	No	7	6	1	1
R:R:F170	R:R:L387	2.44	1	Yes	Yes	7	7	1	2
R:R:K192	R:R:S173	9.18	1	Yes	No	6	4	1	1
R:R:F174	R:R:H178	10.18	1	Yes	No	5	4	1	2
R:R:A380	R:R:F174	2.77	0	No	Yes	4	5	2	1
R:R:F174	R:R:M384	2.49	1	Yes	Yes	5	5	1	2
R:R:D176	R:R:K192	2.77	0	No	Yes	3	6	2	1
R:R:F177	R:R:H178	10.18	0	No	No	4	4	1	2
R:R:F189	R:R:L190	2.44	1	Yes	No	9	5	1	2
R:R:F189	R:R:L193	2.44	1	Yes	No	9	4	1	1
R:R:F189	R:R:P269	5.78	1	Yes	No	9	3	1	2
R:R:I271	R:R:L193	4.28	0	No	No	3	4	2	1
R:R:F200	R:R:V196	2.62	0	No	No	7	7	2	1
R:R:A248	R:R:T197	3.36	0	No	No	7	6	2	1
R:R:F268	R:R:I267	2.51	1	Yes	Yes	5	4	1	2
R:R:F379	R:R:I267	7.54	1	Yes	Yes	4	4	2	2
R:R:F268	R:R:I271	2.51	1	Yes	No	5	3	1	2
R:R:F268	R:R:L276	2.44	1	Yes	No	5	5	1	1
R:R:F268	R:R:F379	3.22	1	Yes	Yes	5	4	1	2
R:R:T283	R:R:W279	8.49	0	No	Yes	8	6	2	1
R:R:M363	R:R:W279	3.49	0	No	Yes	6	6	2	1
R:R:F379	R:R:M363	2.49	1	Yes	No	4	6	2	2
R:R:L387	R:R:M384	5.65	0	Yes	Yes	7	5	2	2
R:R:I169	R:R:S173	1.55	0	No	No	5	4	2	1
R:R:L276	R:R:V367	1.49	1	No	No	5	4	1	2
R:R:F191	R:R:K192	1.24	0	No	Yes	5	6	2	1
R:R:T201	R:R:W279	1.21	0	No	Yes	6	6	2	1
R:R:D184	R:R:F189	1.19	0	No	Yes	2	9	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9EGO_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	1.71
Number of Linked Nodes	225
Number of Links	238
Number of Hubs	25
Number of Links mediated by Hubs	100
Number of Communities	9
Number of Nodes involved in Communities	40
Number of Links involved in Communities	48

Path Summary
Number Of Nodes in MetaPath	61
Number Of Links MetaPath	60
Number of Shortest Paths	21667
Length Of Smallest Path	3
Average Path Length	16.1739
Length of Longest Path	45
Minimum Path Strength	1.19
Average Path Strength	4.65335
Maximum Path Strength	14.61
Minimum Path Correlation	0.7
Average Path Correlation	0.924627
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.77778
Average % Of Corr. Nodes	45.3717
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	34.6699
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• D2 dopamine receptor binding • protein binding • binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • cell communication • G protein-coupled receptor signaling pathway • cellular process • signal transduction • neuropeptide signaling pathway • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to hormone • response to chemical • response to endogenous stimulus • response to peptide hormone • response to oxygen-containing compound • response to nitrogen compound • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • positive regulation of biological process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • positive regulation of cellular process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • regulation of metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • cell surface receptor signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • multicellular organismal process • system process • relaxation of smooth muscle • regulation of system process • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • regulation of localization • establishment of protein localization • nitrogen compound transport • negative regulation of biological process • negative regulation of transport • localization • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of biological quality • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • negative regulation of signaling • hormone secretion • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • regulation of secretion by cell • secretion by cell • signal release • negative regulation of cellular process • negative regulation of protein localization • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating G protein-coupled receptor signaling pathway • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • response to ketone • response to prostaglandin • response to lipid • response to alcohol • response to prostaglandin E • cellular response to forskolin • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to alcohol • response to forskolin • cellular response to lipid • cellular response to ketone • midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle
Gene Ontology	Cellular Component	• midbody • cellular anatomical structure • membrane-bounded organelle • intracellular anatomical structure • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • intracellular membrane-bounded organelle • nucleolus • intracellular organelle lumen • intracellular organelle • organelle lumen • organelle • membraneless organelle • nuclear lumen • cell periphery • cell cortex • cytoplasm • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • extracellular vesicle • extracellular organelle • extracellular region • extracellular space • vesicle • extracellular membrane-bounded organelle • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • cytosol • cell projection • sperm principal piece • cilium • 9+2 motile cilium • sperm flagellum • motile cilium • plasma membrane bounded cell projection • nucleoplasm • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • organelle membrane • lysosome • Golgi apparatus • endomembrane system • ciliary basal body • cannabinoid receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • identical protein binding • protein binding • binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cannabinoid signaling pathway • trans-synaptic signaling • trans-synaptic signaling by endocannabinoid • retrograde trans-synaptic signaling • cell-cell signaling • retrograde trans-synaptic signaling by endocannabinoid • synaptic signaling • trans-synaptic signaling by lipid • retrograde trans-synaptic signaling by lipid • multicellular organismal process • neuron recognition • cellular developmental process • cell projection organization • cell development • neuron projection development • neuron projection fasciculation • cellular component organization • neurogenesis • multicellular organism development • neuron differentiation • axonal fasciculation • cell differentiation • anatomical structure development • cell recognition • cellular component organization or biogenesis • system development • developmental process • plasma membrane bounded cell projection organization • nervous system development • axon development • generation of neurons • neuron development • inorganic ion homeostasis • intracellular calcium ion homeostasis • homeostatic process • calcium ion homeostasis • regulation of cytosolic calcium ion concentration • regulation of presynaptic cytosolic calcium ion concentration • cellular homeostasis • neuron cellular homeostasis • chemical homeostasis • intracellular monoatomic cation homeostasis • monoatomic ion homeostasis • intracellular chemical homeostasis • monoatomic cation homeostasis • intracellular monoatomic ion homeostasis • glucose homeostasis • carbohydrate homeostasis • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • actin cytoskeleton • mitochondrial membrane • mitochondrion • organelle outer membrane • organelle envelope • mitochondrial envelope • mitochondrial outer membrane • outer membrane • presynapse • synapse • cell junction • presynaptic membrane • plasma membrane region • synaptic membrane • membrane microdomain • membrane raft • growth cone • axon • distal axon • neuron projection • site of polarized growth • GABA-ergic synapse • glutamatergic synapse • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium
SCOP2	Domain Identifier	• Ras-like P-loop GTPases • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Ras-like P-loop GTPases • G protein-coupled receptor-like • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	YVF
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	YVF
Name	methyl (2R)-2-({(1M)-5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonyl}amino)-2-(thiophen-2-yl)propanoate
Synonyms
Identifier
Formula	C20 H18 F3 N3 O3 S
Molecular Weight	437.435
SMILES
PubChem	170838490
Formal Charge	0
Total Atoms	48
Total Chiral Atoms	1
Total Bonds	50
Total Aromatic Bonds	16


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P21554
Sequence	>9EGO_nogp_Chain_R F M V L N P S Q Q L A I A V L S L T L G T F T V L E N L L V L C V I R C R P S Y H F I G S L A V A D L L G S V I F V Y S F I D F H V F H R K D S R N V F L F K L G G V T A S F T A S V G S L F L T A I D R Y I S I H R P L A Y K R I V T R P K A V V A F C L M W T I A I V I A V L P L L D I F P H I D E T Y L M F W I G V T S V L L L F I V Y A Y M Y I L W K A H S H A V R M I Q R G T A R M D I R L A K T L V L I L V V L I I C W G P L L A I M V Y D V F G K M N K L I K T V F A F C S M L C L L N S T V N P I I Y A L R S K D L R H A F R S M Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5TGZ	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM6538	-	-	2.8	2016-11-02	doi.org/10.1016/j.cell.2016.10.004
	5U09	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Taranabant	-	-	2.6	2016-12-07	doi.org/10.1038/nature20613
	5XR8	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM12033	-	-	2.95	2017-07-12	doi.org/10.1038/nature23272
	5XRA	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM11542	-	-	2.8	2017-07-12	doi.org/10.1038/nature23272
	6N4B	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MDMB-Fubinaca	-	Gi1/β1/γ2	3	2019-01-30	doi.org/10.1016/j.cell.2018.11.040
	6N4B (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MDMB-Fubinaca	-		3	2019-01-30	doi.org/10.1016/j.cell.2018.11.040
	6KQI	A	Lipid	Cannabinoid	CB₁	Homo sapiens	CP55940	Org27569	-	3.25	2019-10-23	doi.org/10.1038/s41589-019-0387-2
	6KPG	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM841	-	Gi1/β1/γ2	3	2020-02-12	doi.org/10.1016/j.cell.2020.01.008
	6KPG (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM841	-		3	2020-02-12	doi.org/10.1016/j.cell.2020.01.008
	7V3Z	A	Lipid	Cannabinoid	CB₁	Homo sapiens	CP55940	-	-	3.29	2021-11-24	doi.org/10.1021/jacs.1c06847
	7FEE	A	Lipid	Cannabinoid	CB₁	Homo sapiens	CP55940	ZCZ011	-	2.7	2022-06-15	doi.org/10.1038/s41589-022-01038-y
	7WV9	A	Lipid	Cannabinoid	CB₁	Homo sapiens	CP55940	ZCZ011	Gi2/β1/γ2	3.36	2022-06-15	doi.org/10.1038/s41589-022-01038-y
	7WV9 (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	CP55940	ZCZ011		3.36	2022-06-15	doi.org/10.1038/s41589-022-01038-y
	8GHV	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AMG315	-	Gi1/β1/γ2	2.8	2023-05-24	doi.org/10.1038/s41467-023-37864-4
	8GHV (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AMG315	-		2.8	2023-05-24	doi.org/10.1038/s41467-023-37864-4
	8IKG	A	Lipid	Cannabinoid	CB₁	Homo sapiens	-	PubChem 703205	Gi1/β1/γ1	3.4	2024-06-05	doi.org/10.1073/pnas.2321532121
	8IKG (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	-	PubChem 703205		3.4	2024-06-05	doi.org/10.1073/pnas.2321532121
	8IKH	A	Lipid	Cannabinoid	CB₁	Homo sapiens	-	PubChem 171393541	Gi1/β1/γ1	3.3	2024-06-05	doi.org/10.1073/pnas.2321532121
	8IKH (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	-	PubChem 171393541		3.3	2024-06-05	doi.org/10.1073/pnas.2321532121
	9ERX	A	Lipid	Cannabinoid	CB₁	Homo sapiens	D9-THC analog	-	Gi1/β1/γ2	2.9	2024-06-26	doi.org/10.21203/rs.3.rs-4277209/v1
	9ERX (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	D9-THC analog	-		2.9	2024-06-26	doi.org/10.21203/rs.3.rs-4277209/v1
	9B9Z	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MRI-1867	-	-	3.3	2024-11-20	doi.org/10.1038/s41467-024-54206-0
	9BA0	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MRI-1891	-	-	3.13	2024-11-20	doi.org/10.1038/s41467-024-54206-0
	9B54	A	Lipid	Cannabinoid	CB₁	Homo sapiens	VIP36	-	Gi1/β1/γ2	2.86	2025-03-05	doi.org/10.1038/s41586-025-08618-7
	9B54 (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	VIP36	-		2.86	2025-03-05	doi.org/10.1038/s41586-025-08618-7
	9B65	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MDMB-Fubinaca	-	Gi1/β1/γ2	3.03	2025-03-05	doi.org/10.1038/s41586-025-08618-7
	9B65 (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MDMB-Fubinaca	-		3.03	2025-03-05	doi.org/10.1038/s41586-025-08618-7
	8K8J	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Fenofibrate	-	chim(Gs-CtGq)/β1/γ2	2.88	2024-02-14	doi.org/10.1002/advs.202306311
	8K8J (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Fenofibrate	-		2.88	2024-02-14	doi.org/10.1002/advs.202306311
	8GAG	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Z8526711350	-	Gi1/β1/γ2	3.3	2024-02-28	To be published
	8GAG (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Z8526711350	-		3.3	2024-02-28	To be published
	8WRZ	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM841	-	Arrestin2	3.6	2024-02-28	AM841
	8WU1	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MDMB-Fubinaca	-	Arrestin2	3.2	2024-03-20	doi.org/10.1016/j.cell.2023.11.017
	9B9Y	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Taranabant	-	-	3.5	2024-11-20	doi.org/10.1038/s41467-024-54206-0
	9DGI	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Z8526711350	-	-	3.35	2025-04-30	doi.org/10.1038/s41467-025-57136-7
	9EGO	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Z8526711350	-	Gi1/β1/γ2	3.2	2025-04-30	doi.org/10.1038/s41467-025-57136-7
	9EGO (No Gprot)	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Z8526711350	-		3.2	2025-04-30	doi.org/10.1038/s41467-025-57136-7

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