psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:I19	A:A:R15	2.51	No	No	0	9	5
2	A:A:S16	B:B:N88	4.47	No	No	0	7	7
3	A:A:S16	B:B:K89	6.12	No	Yes	0	7	9
4	A:A:I19	B:B:K89	7.27	No	Yes	0	9	9
5	A:A:R21	A:A:R24	6.4	No	No	0	4	3
6	A:A:L23	B:B:L55	2.77	No	No	0	6	6
7	A:A:L23	B:B:I80	2.85	No	Yes	0	6	8
8	A:A:D26	B:B:K78	8.3	No	No	0	5	8
9	A:A:E28	R:R:T149	4.23	No	No	0	4	8
10	A:A:E33	A:A:K197	10.8	No	Yes	0	6	6
11	A:A:F196	A:A:V34	6.55	Yes	No	18	7	5
12	A:A:T219	A:A:V34	6.35	No	No	0	7	5
13	A:A:V339	A:A:V34	3.21	No	No	18	8	5
14	A:A:F199	A:A:K35	6.2	Yes	No	0	5	9
15	A:A:F196	A:A:L36	4.87	Yes	No	0	7	7
16	A:A:I222	A:A:L36	4.28	Yes	No	0	7	7
17	A:A:L37	A:A:L39	6.92	No	Yes	1	9	9
18	A:A:F215	A:A:L37	9.74	Yes	No	1	9	9
19	A:A:I221	A:A:L37	2.85	Yes	No	1	8	9
20	A:A:K46	A:A:L38	5.64	Yes	Yes	8	9	8
21	A:A:L38	A:A:M198	5.65	Yes	No	0	8	7
22	A:A:D200	A:A:L38	6.79	No	Yes	8	9	8
23	A:A:I222	A:A:L38	2.85	Yes	Yes	8	7	8
24	A:A:I221	A:A:L39	2.85	Yes	Yes	1	8	9
25	A:A:F223	A:A:L39	2.44	Yes	Yes	1	9	9
26	A:A:I253	A:A:L39	4.28	Yes	Yes	1	8	9
27	A:A:G40	A:A:K46	5.23	No	Yes	0	9	9
28	A:A:A41	A:A:S44	3.42	No	No	0	7	9
29	A:A:A226	A:A:S44	3.42	No	No	0	8	9
30	A:A:G45	A:A:T48	3.64	No	No	0	9	9
31	A:A:D200	A:A:K46	8.3	No	Yes	8	9	9
32	A:A:C224	A:A:K46	3.23	No	Yes	0	7	9
33	A:A:I49	A:A:M53	4.37	No	Yes	0	7	8
34	A:A:C224	A:A:I49	3.27	No	No	0	7	7
35	A:A:I49	A:A:N269	8.5	No	Yes	0	7	9
36	A:A:T187	A:A:V50	4.76	No	No	0	6	6
37	A:A:M53	A:A:Q52	6.8	Yes	No	0	8	9
38	A:A:N331	A:A:Q52	11.88	Yes	No	0	8	9
39	A:A:F189	A:A:M53	11.2	Yes	Yes	0	9	8
40	A:A:M53	A:A:V332	3.04	Yes	No	0	8	7
41	A:A:I55	A:A:K54	2.91	No	No	0	8	7
42	A:A:T182	B:B:N119	4.39	No	No	0	7	9
43	A:A:F199	A:A:I184	2.51	Yes	Yes	1	5	9
44	A:A:I184	A:A:V201	4.61	Yes	No	1	9	9
45	A:A:I184	B:B:W99	4.7	Yes	Yes	1	9	9
46	A:A:I184	B:B:L117	7.14	Yes	No	1	9	9
47	A:A:E186	A:A:K197	2.7	No	Yes	1	9	6
48	A:A:E186	A:A:F199	7	No	Yes	1	9	5
49	A:A:F189	A:A:T187	7.78	Yes	No	0	9	6
50	A:A:H188	A:A:K197	10.48	No	Yes	0	3	6
51	A:A:F189	A:A:M198	3.73	Yes	No	0	9	7
52	A:A:H195	A:A:T190	6.85	No	No	0	4	3
53	A:A:F191	A:A:K192	13.65	Yes	No	17	5	4
54	A:A:F191	A:A:V332	9.18	Yes	No	0	5	7
55	A:A:F191	A:A:Q333	3.51	Yes	No	17	5	5
56	A:A:F191	A:A:F336	3.22	Yes	Yes	17	5	8
57	A:A:K192	A:A:Q333	5.42	No	No	17	4	5
58	A:A:F336	A:A:K192	2.48	Yes	No	17	8	4
59	A:A:F196	A:A:L194	9.74	Yes	No	0	7	4
60	A:A:F336	A:A:L194	3.65	Yes	No	0	8	4
61	A:A:L194	R:R:V145	4.47	No	No	0	4	6
62	A:A:F196	A:A:V339	9.18	Yes	No	18	7	8
63	A:A:F199	A:A:K197	3.72	Yes	Yes	1	5	6
64	A:A:F199	B:B:W99	13.03	Yes	Yes	1	5	9
65	A:A:V201	A:A:W211	6.13	No	Yes	1	9	9
66	A:A:F215	A:A:V201	3.93	Yes	No	1	9	9
67	A:A:Q204	A:A:S206	5.78	No	No	1	9	8
68	A:A:Q204	A:A:W211	4.38	No	Yes	1	9	9
69	A:A:S206	A:A:W211	4.94	No	Yes	1	8	9
70	A:A:S206	B:B:Y145	5.09	No	Yes	1	8	8
71	A:A:E207	A:A:K209	4.05	Yes	No	0	9	8
72	A:A:E207	A:A:K210	4.05	Yes	No	0	9	9
73	A:A:E207	B:B:C204	4.56	Yes	Yes	1	9	7
74	A:A:E207	B:B:D228	3.9	Yes	No	1	9	9
75	A:A:R208	A:A:W211	8	Yes	Yes	0	9	9
76	A:A:I212	A:A:R208	5.01	No	Yes	0	8	9
77	A:A:L249	A:A:R208	4.86	No	Yes	0	9	9
78	A:A:K210	B:B:M188	5.76	No	Yes	0	9	8
79	A:A:K210	B:B:N230	4.2	No	No	0	9	9
80	A:A:F215	A:A:W211	4.01	Yes	Yes	1	9	9
81	A:A:I212	A:A:N256	4.25	No	Yes	1	8	8
82	A:A:F259	A:A:I212	5.02	Yes	No	1	9	8
83	A:A:H213	A:A:W258	10.58	No	Yes	0	8	5
84	A:A:H213	B:B:W332	5.29	No	Yes	0	8	9
85	A:A:C214	B:B:Y59	6.72	No	Yes	1	7	8
86	A:A:C214	B:B:Q75	3.05	No	No	1	7	9
87	A:A:C214	B:B:W99	2.61	No	Yes	1	7	9
88	A:A:F215	A:A:V218	2.62	Yes	No	1	9	9
89	A:A:F215	B:B:W99	7.02	Yes	Yes	1	9	9
90	A:A:F215	B:B:L117	2.44	Yes	No	1	9	9
91	A:A:E216	A:A:W258	3.27	No	Yes	0	7	5
92	A:A:F259	A:A:V218	2.62	Yes	No	1	9	9
93	A:A:T262	A:A:V218	3.17	No	No	1	7	9
94	A:A:I221	A:A:I253	2.94	Yes	Yes	1	8	8
95	A:A:F259	A:A:I221	8.79	Yes	Yes	1	9	8
96	A:A:I221	A:A:T262	4.56	Yes	No	1	8	7
97	A:A:I222	A:A:I265	2.94	Yes	Yes	8	7	8
98	A:A:F267	A:A:I222	2.51	Yes	Yes	8	9	7
99	A:A:F223	A:A:V225	2.62	Yes	No	1	9	7
100	A:A:F223	A:A:L249	6.09	Yes	No	1	9	9
101	A:A:F223	A:A:F250	15	Yes	Yes	0	9	9
102	A:A:F223	A:A:I253	2.51	Yes	Yes	1	9	8
103	A:A:F223	A:A:L266	3.65	Yes	No	0	9	9
104	A:A:L268	A:A:V225	2.98	Yes	No	1	8	7
105	A:A:F307	A:A:V225	2.62	Yes	No	1	8	7
106	A:A:A226	A:A:D229	4.63	No	No	0	8	8
107	A:A:L227	A:A:L268	8.3	No	Yes	0	7	8
108	A:A:F274	A:A:L227	7.31	Yes	No	0	9	7
109	A:A:K270	A:A:S228	3.06	No	No	20	9	9
110	A:A:L273	A:A:S228	6.01	No	No	20	6	9
111	A:A:D229	A:A:R242	8.34	No	Yes	0	8	9
112	A:A:F274	A:A:Y230	7.22	Yes	No	0	9	8
113	A:A:K277	A:A:Y230	4.78	No	No	0	9	8
114	A:A:C286	A:A:Y230	5.38	Yes	No	0	6	8
115	A:A:D231	A:A:K277	4.15	No	No	0	9	9
116	A:A:L232	A:A:L234	2.77	No	No	21	8	8
117	A:A:L232	A:A:R242	13.36	No	Yes	21	8	9
118	A:A:N241	A:A:V233	7.39	No	No	0	9	5
119	A:A:L234	A:A:R242	7.29	No	Yes	21	8	9
120	A:A:C286	A:A:M243	3.24	Yes	No	0	6	8
121	A:A:F307	A:A:M243	3.73	Yes	No	0	8	8
122	A:A:M247	A:A:Q306	6.8	No	No	0	6	5
123	A:A:I253	A:A:L249	7.14	Yes	No	1	8	9
124	A:A:F250	A:A:I264	5.02	Yes	No	0	9	6
125	A:A:F250	A:A:L310	3.65	Yes	No	0	9	4
126	A:A:F250	A:A:I319	3.77	Yes	No	0	9	5
127	A:A:D251	A:A:N255	9.42	No	No	24	5	8
128	A:A:D251	A:A:L310	2.71	No	No	0	5	4
129	A:A:D251	A:A:K312	2.77	No	No	24	5	5
130	A:A:C254	A:A:I264	3.27	No	No	23	5	6
131	A:A:C254	A:A:K317	6.47	No	No	23	5	7
132	A:A:K312	A:A:N255	8.39	No	No	24	5	8
133	A:A:K257	A:A:N256	2.8	No	Yes	1	4	8
134	A:A:N256	A:A:W258	12.43	Yes	Yes	1	8	5
135	A:A:F259	A:A:N256	6.04	Yes	Yes	1	9	8
136	A:A:K257	A:A:W258	10.44	No	Yes	1	4	5
137	A:A:F259	A:A:T262	10.38	Yes	No	1	9	7
138	A:A:R313	A:A:T260	6.47	No	No	0	4	3
139	A:A:D261	A:A:T316	4.34	No	No	0	4	3
140	A:A:D261	A:A:N346	5.39	No	No	0	4	4
141	A:A:S263	A:A:Y320	2.54	No	No	0	7	7
142	A:A:S263	A:A:V342	4.85	No	No	0	7	7
143	A:A:I264	A:A:K317	2.91	No	No	23	6	7
144	A:A:F267	A:A:I265	3.77	Yes	Yes	8	9	8
145	A:A:F334	A:A:I265	2.51	No	Yes	0	3	8
146	A:A:A338	A:A:I265	3.25	No	Yes	0	6	8
147	A:A:F307	A:A:L266	3.65	Yes	No	0	8	9
148	A:A:L266	A:A:T321	7.37	No	No	0	9	5
149	A:A:F267	A:A:H322	5.66	Yes	No	8	9	9
150	A:A:F267	A:A:T324	6.49	Yes	No	8	9	9
151	A:A:F267	A:A:N331	4.83	Yes	Yes	8	9	8
152	A:A:F267	A:A:V335	2.62	Yes	No	0	9	8
153	A:A:F307	A:A:L268	2.44	Yes	Yes	1	8	8
154	A:A:F323	A:A:L268	4.87	No	Yes	0	4	8
155	A:A:K270	A:A:N269	2.8	No	Yes	0	9	9
156	A:A:N269	A:A:T324	8.77	Yes	No	0	9	9
157	A:A:K270	A:A:L273	11.28	No	No	20	9	6
158	A:A:K271	A:A:Y296	4.78	No	Yes	0	5	4
159	A:A:F323	A:A:K271	7.44	No	No	0	4	5
160	A:A:C325	A:A:K271	3.23	No	No	0	7	5
161	A:A:D272	A:A:E276	9.09	No	No	0	9	5
162	A:A:F274	A:A:I278	10.05	Yes	No	19	9	6
163	A:A:F274	A:A:Y296	4.13	Yes	Yes	19	9	4
164	A:A:A299	A:A:F274	2.77	No	Yes	0	7	9
165	A:A:E275	A:A:K279	16.2	No	No	0	5	2
166	A:A:I278	A:A:Y296	3.63	No	Yes	19	6	4
167	A:A:P282	A:A:S281	3.56	No	No	0	5	7
168	A:A:P282	A:A:T284	3.5	No	No	0	5	4
169	A:A:L283	A:A:Y287	3.52	No	Yes	0	7	7
170	A:A:C286	A:A:Y287	6.72	Yes	Yes	0	6	7
171	A:A:Y287	A:A:Y302	3.97	Yes	No	22	7	6
172	A:A:I303	A:A:Y287	4.84	No	Yes	0	7	7
173	A:A:Q306	A:A:Y287	13.53	No	Yes	22	5	7
174	A:A:G292	A:A:Y290	4.35	No	No	0	7	7
175	A:A:E298	A:A:Y290	10.1	No	No	0	4	7
176	A:A:Y290	A:A:Y302	34.75	No	No	0	7	6
177	A:A:S293	A:A:T295	7.99	No	No	26	3	5
178	A:A:E298	A:A:S293	5.75	No	No	26	4	3
179	A:A:E298	A:A:T295	4.23	No	No	26	4	5
180	A:A:E297	A:A:Y296	5.61	No	Yes	0	4	4
181	A:A:A300	A:A:F323	2.77	No	No	0	5	4
182	A:A:Q306	A:A:Y302	3.38	No	No	22	5	6
183	A:A:F307	A:A:I303	7.54	Yes	No	0	8	7
184	A:A:E308	A:A:Q304	3.82	No	No	25	3	5
185	A:A:Q304	A:A:T321	7.09	No	No	25	5	5
186	A:A:E308	A:A:I319	2.73	No	No	0	3	5
187	A:A:E308	A:A:T321	4.23	No	No	25	3	5
188	A:A:K314	A:A:N311	8.39	No	No	0	3	8
189	A:A:I319	A:A:N311	5.66	No	No	0	5	8
190	A:A:K317	A:A:R313	4.95	No	No	0	7	4
191	A:A:D315	R:R:M335	11.09	No	No	27	3	4
192	A:A:D315	R:R:R339	4.76	No	No	27	3	7
193	A:A:E318	A:A:K345	2.7	No	No	0	4	5
194	A:A:A338	A:A:Y320	2.67	No	No	0	6	7
195	A:A:K345	A:A:Y320	4.78	No	No	0	5	7
196	A:A:H322	A:A:N331	2.55	No	Yes	8	9	8
197	A:A:F334	A:A:H322	20.36	No	No	0	3	9
198	A:A:N331	A:A:T324	7.31	Yes	No	8	8	9
199	A:A:K330	A:A:T327	7.51	No	No	0	4	8
200	A:A:D328	A:A:T329	5.78	No	No	0	9	9
201	A:A:D337	A:A:Q333	7.83	No	No	0	4	5
202	A:A:F336	A:A:T340	7.78	Yes	No	0	8	6
203	A:A:I343	A:A:V339	3.07	No	No	0	7	8
204	A:A:T340	R:R:P141	3.5	No	No	0	6	8
205	A:A:D341	R:R:R225	9.53	No	No	0	8	7
206	A:A:N346	A:A:V342	4.43	No	No	0	4	7
207	A:A:I343	A:A:N347	4.25	No	No	0	7	8
208	A:A:I344	A:A:L348	2.85	No	Yes	0	6	9
209	A:A:I344	R:R:P141	8.47	No	No	0	6	8
210	A:A:I344	R:R:R225	6.26	No	No	0	6	7
211	A:A:F354	A:A:K345	4.96	Yes	No	0	5	5
212	A:A:N347	R:R:Y144	22.1	No	No	0	8	8
213	A:A:L348	A:A:L353	4.15	Yes	Yes	0	9	7
214	A:A:F354	A:A:L348	2.44	Yes	Yes	0	5	9
215	A:A:L348	R:R:I138	8.56	Yes	No	0	9	9
216	A:A:F354	A:A:K349	8.69	Yes	No	0	5	5
217	A:A:C351	A:A:L353	6.35	No	Yes	0	4	7
218	A:A:C351	R:R:R134	6.96	No	No	0	4	9
219	A:A:G352	W:W:?1	3.43	No	Yes	0	8	0
220	A:A:L353	R:R:T343	5.9	Yes	No	0	7	8
221	A:A:L353	R:R:T346	2.95	Yes	Yes	0	7	8
222	A:A:L353	R:R:L347	4.15	Yes	No	0	7	8
223	A:A:F354	R:R:I226	3.77	Yes	No	0	5	6
224	A:A:F354	R:R:R339	22.45	Yes	No	0	5	7
225	G:G:E22	G:G:Q18	10.19	No	No	0	9	9
226	B:B:C218	G:G:E22	6.08	No	No	0	5	9
227	G:G:I25	G:G:R27	5.01	No	No	0	2	8
228	B:B:Q220	G:G:I25	4.12	No	No	0	7	2
229	B:B:A21	G:G:R27	2.77	No	No	0	4	8
230	B:B:D258	G:G:R27	10.72	Yes	No	0	7	8
231	B:B:R256	G:G:I28	15.03	No	No	0	9	4
232	G:G:K29	G:G:S31	4.59	No	No	28	4	9
233	B:B:D27	G:G:K29	11.06	No	No	28	8	4
234	B:B:D27	G:G:S31	4.42	No	No	28	8	9
235	G:G:D36	G:G:K32	12.44	No	No	0	5	5
236	B:B:D254	G:G:A33	3.09	Yes	No	0	9	7
237	B:B:L30	G:G:A34	4.73	Yes	No	0	5	6
238	B:B:F235	G:G:L37	4.87	Yes	No	0	6	7
239	B:B:I33	G:G:M38	4.37	No	Yes	0	3	4
240	B:B:T34	G:G:M38	3.01	Yes	Yes	11	5	4
241	B:B:I37	G:G:M38	5.83	No	Yes	0	2	4
242	B:B:L300	G:G:M38	2.83	Yes	Yes	11	6	4
243	G:G:H44	G:G:Y40	6.53	No	Yes	0	6	6
244	B:B:F235	G:G:Y40	4.13	Yes	Yes	14	6	6
245	B:B:P236	G:G:Y40	4.17	Yes	Yes	14	7	6
246	B:B:N237	G:G:Y40	10.47	No	Yes	0	5	6
247	B:B:R283	G:G:C41	4.18	Yes	No	0	9	7
248	G:G:A43	G:G:H44	2.93	No	No	0	4	6
249	G:G:E47	G:G:K46	8.1	No	No	0	3	1
250	G:G:D48	G:G:L51	2.71	Yes	No	0	9	6
251	B:B:S279	G:G:D48	2.94	No	Yes	0	9	9
252	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
253	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
254	B:B:V320	G:G:L50	2.98	No	No	0	7	9
255	B:B:R283	G:G:L51	2.43	Yes	No	0	9	6
256	G:G:P55	G:G:V54	3.53	No	Yes	2	5	6
257	G:G:E58	G:G:V54	4.28	No	Yes	2	5	6
258	G:G:N59	G:G:V54	7.39	Yes	Yes	2	9	6
259	B:B:N340	G:G:V54	4.43	Yes	Yes	2	9	6
260	G:G:E58	G:G:P55	9.43	No	No	2	5	5
261	G:G:A56	G:G:R62	2.77	No	No	0	4	7
262	G:G:N59	G:G:P60	6.52	Yes	No	2	9	9
263	G:G:F61	G:G:N59	6.04	Yes	Yes	2	8	9
264	B:B:M325	G:G:N59	2.8	Yes	Yes	2	5	9
265	B:B:N340	G:G:N59	6.81	Yes	Yes	2	9	9
266	B:B:Y85	G:G:P60	4.17	No	No	2	4	9
267	B:B:M325	G:G:P60	10.06	Yes	No	2	5	9
268	B:B:R49	G:G:F61	8.55	No	Yes	0	7	8
269	B:B:S84	G:G:F61	7.93	No	Yes	0	5	8
270	B:B:M325	G:G:F61	3.73	Yes	Yes	2	5	8
271	B:B:A326	G:G:F61	4.16	No	Yes	2	7	8
272	B:B:I338	G:G:F61	5.02	No	Yes	0	5	8
273	B:B:N340	G:G:F61	3.62	Yes	Yes	2	9	8
274	R:R:L41	R:R:V37	2.98	No	No	0	4	5
275	R:R:A94	R:R:L43	4.73	No	Yes	9	7	7
276	R:R:L43	R:R:W387	10.25	Yes	Yes	9	7	8
277	R:R:L46	R:R:S391	6.01	No	No	0	7	5
278	R:R:L394	R:R:L46	2.77	No	No	0	7	7
279	R:R:I47	R:R:L90	4.28	No	Yes	0	7	8
280	R:R:F48	R:R:L52	13.4	No	No	0	4	4
281	R:R:A50	R:R:S86	3.42	No	Yes	0	8	8
282	R:R:A50	R:R:L394	3.15	No	No	0	8	7
283	R:R:L83	R:R:V51	2.98	No	No	0	8	7
284	R:R:S86	R:R:V51	3.23	Yes	No	0	8	7
285	R:R:G53	R:R:Y402	2.9	No	Yes	6	9	6
286	R:R:G53	W:W:?1	3.43	No	Yes	6	9	0
287	R:R:D82	R:R:N54	6.73	Yes	Yes	3	9	9
288	R:R:L83	R:R:N54	6.87	No	Yes	0	8	9
289	R:R:N54	R:R:S86	2.98	Yes	Yes	0	9	8
290	R:R:N54	R:R:P397	4.89	Yes	No	3	9	9
291	R:R:C56	R:R:Y402	2.69	No	Yes	6	8	6
292	R:R:C56	R:R:F411	2.79	No	Yes	6	8	8
293	R:R:I61	R:R:V57	3.07	No	Yes	0	8	9
294	R:R:A79	R:R:V57	3.39	No	Yes	0	9	9
295	R:R:A401	R:R:V57	3.39	No	Yes	6	8	9
296	R:R:V57	R:R:Y402	5.05	Yes	Yes	6	9	6
297	R:R:F407	R:R:V57	6.55	Yes	Yes	6	8	9
298	R:R:A60	R:R:F407	2.77	No	Yes	6	8	8
299	R:R:A60	R:R:F411	4.16	No	Yes	6	8	8
300	R:R:A410	R:R:E64	4.53	No	No	0	8	7
301	R:R:E64	R:R:K413	8.1	No	No	0	7	6
302	R:R:E64	R:R:I414	12.3	No	No	0	7	7
303	R:R:Q68	R:R:R65	3.5	No	No	0	8	7
304	B:B:F335	R:R:R65	3.21	Yes	No	0	4	7
305	R:R:L67	R:R:S66	3	Yes	No	0	8	6
306	R:R:L67	R:R:N72	4.12	Yes	No	0	8	9
307	R:R:F407	R:R:L67	2.44	Yes	Yes	0	8	8
308	R:R:A410	R:R:L67	4.73	No	Yes	0	8	8
309	R:R:Q68	R:R:Y73	6.76	No	No	0	8	6
310	R:R:N69	R:R:N72	6.81	No	No	0	8	9
311	R:R:R148	R:R:V70	14.38	No	No	0	8	7
312	R:R:P150	R:R:Y73	4.17	No	No	0	5	6
313	R:R:I130	R:R:L74	4.28	Yes	Yes	0	9	8
314	R:R:D133	R:R:L74	5.43	No	Yes	0	9	8
315	R:R:A153	R:R:L74	3.15	No	Yes	0	7	8
316	R:R:L156	R:R:L74	4.15	No	Yes	0	6	8
317	R:R:H126	R:R:S77	9.76	Yes	No	3	8	9
318	R:R:I157	R:R:S77	9.29	No	No	3	8	9
319	R:R:D82	R:R:L78	2.71	Yes	Yes	3	9	9
320	R:R:L78	R:R:S123	3	Yes	No	3	9	9
321	R:R:H126	R:R:L78	2.57	Yes	Yes	3	8	9
322	R:R:L127	R:R:L78	6.92	Yes	Yes	0	8	9
323	R:R:I130	R:R:L78	2.85	Yes	Yes	0	9	9
324	R:R:S122	R:R:T81	6.4	No	No	3	8	9
325	R:R:H126	R:R:T81	6.85	Yes	No	3	8	9
326	R:R:D82	R:R:S123	2.94	Yes	No	3	9	9
327	R:R:D82	R:R:N396	2.69	Yes	No	0	9	9
328	R:R:D82	R:R:P397	4.83	Yes	No	3	9	9
329	R:R:L83	R:R:V87	2.98	No	No	0	8	6
330	R:R:C119	R:R:M84	3.24	No	No	0	7	7
331	R:R:L90	R:R:V85	2.98	Yes	No	0	8	8
332	R:R:C119	R:R:V85	3.42	No	No	0	7	8
333	R:R:S393	R:R:V85	3.23	No	No	0	9	8
334	R:R:L90	R:R:S86	3	Yes	Yes	0	8	8
335	R:R:L88	R:R:V87	2.98	No	No	0	6	6
336	R:R:L115	R:R:L88	4.15	No	No	0	5	6
337	R:R:F112	R:R:V89	3.93	Yes	No	0	6	8
338	R:R:L115	R:R:V89	4.47	No	No	0	5	8
339	R:R:D116	R:R:V89	7.3	No	No	0	8	8
340	R:R:L90	R:R:Y390	4.69	Yes	Yes	0	8	8
341	R:R:F112	R:R:M92	9.95	Yes	No	0	6	6
342	R:R:A93	R:R:F112	2.77	No	Yes	0	7	6
343	R:R:A93	R:R:W387	2.59	No	Yes	9	7	8
344	R:R:A93	R:R:Y390	2.67	No	Yes	9	7	8
345	R:R:A94	R:R:W387	2.59	No	Yes	9	7	8
346	R:R:L95	R:R:L99	6.92	No	No	9	6	5
347	R:R:W102	R:R:Y96	3.86	Yes	No	0	9	6
348	R:R:Q97	R:R:W387	6.57	No	Yes	0	7	8
349	R:R:K101	R:R:T103	4.5	No	No	0	5	5
350	R:R:D185	R:R:K101	9.68	No	No	0	4	5
351	R:R:L104	R:R:W102	6.83	No	Yes	12	7	9
352	R:R:T108	R:R:W102	3.64	No	Yes	12	6	9
353	R:R:C109	R:R:W102	6.53	No	Yes	12	9	9
354	R:R:F112	R:R:W102	5.01	Yes	Yes	0	6	9
355	R:R:C187	R:R:W102	7.84	No	Yes	12	9	9
356	R:R:L104	R:R:T108	7.37	No	No	12	7	6
357	R:R:C109	R:R:I113	3.27	No	No	12	9	7
358	R:R:C109	R:R:C187	7.28	No	No	12	9	9
359	R:R:D110	R:R:M172	6.93	No	No	0	7	6
360	R:R:C187	R:R:I113	3.27	No	No	12	9	7
361	R:R:I113	R:R:I189	4.42	No	No	0	7	6
362	R:R:C119	R:R:L115	3.17	No	No	0	7	5
363	R:R:C120	R:R:D116	4.67	No	No	0	7	8
364	R:R:D116	R:R:Y390	12.64	No	Yes	0	8	8
365	R:R:L118	R:R:W161	3.42	No	Yes	0	6	9
366	R:R:F165	R:R:L118	9.74	No	No	0	5	6
367	R:R:L118	R:R:S168	4.5	No	No	0	6	8
368	R:R:C120	R:R:W358	5.22	No	Yes	0	7	8
369	R:R:T121	R:R:W125	2.43	Yes	Yes	0	8	7
370	R:R:G164	R:R:T121	3.64	No	Yes	0	8	8
371	R:R:I167	R:R:T121	7.6	No	Yes	0	8	8
372	R:R:H126	R:R:S122	8.37	Yes	No	3	8	8
373	R:R:S122	R:R:W161	13.59	No	Yes	3	8	9
374	R:R:I124	R:R:P207	3.39	Yes	Yes	3	8	9
375	R:R:F354	R:R:I124	3.77	Yes	Yes	0	9	8
376	R:R:I124	R:R:W358	7.05	Yes	Yes	3	8	8
377	R:R:F362	R:R:I124	2.51	No	Yes	3	7	8
378	R:R:C128	R:R:W125	3.92	No	Yes	3	7	7
379	R:R:T160	R:R:W125	2.43	Yes	Yes	3	8	7
380	R:R:I163	R:R:W125	7.05	No	Yes	0	5	7
381	R:R:P207	R:R:W125	6.76	Yes	Yes	3	9	7
382	R:R:H126	R:R:I157	6.63	Yes	No	3	8	8
383	R:R:H126	R:R:T160	10.95	Yes	Yes	3	8	8
384	R:R:H126	R:R:W161	5.29	Yes	Yes	3	8	9
385	R:R:F354	R:R:L127	2.44	Yes	Yes	0	9	8
386	R:R:L127	R:R:N396	8.24	Yes	No	0	8	9
387	R:R:L127	R:R:Y400	5.86	Yes	Yes	0	8	9
388	R:R:C128	R:R:P207	3.77	No	Yes	3	7	9
389	R:R:C128	R:R:L210	4.76	No	No	0	7	7
390	R:R:I130	R:R:R134	3.76	Yes	No	0	9	9
391	R:R:I130	R:R:Y400	6.04	Yes	Yes	0	9	9
392	R:R:A131	R:R:M211	3.22	No	No	29	9	9
393	R:R:A131	R:R:Y215	4	No	Yes	29	9	9
394	R:R:L132	R:R:W136	15.94	No	No	0	6	5
395	R:R:L132	R:R:L214	4.15	No	No	0	6	7
396	R:R:D133	R:R:R148	9.53	No	No	0	9	8
397	R:R:R134	W:W:?1	6.51	No	Yes	0	9	0
398	R:R:W136	R:R:Y135	3.86	No	Yes	0	5	9
399	R:R:T139	R:R:Y135	16.23	No	Yes	0	8	9
400	R:R:L214	R:R:Y135	5.86	No	Yes	0	7	9
401	R:R:R217	R:R:Y135	13.38	No	Yes	0	7	9
402	R:R:I218	R:R:Y135	3.63	No	Yes	0	9	9
403	R:R:R152	R:R:W136	6	No	No	0	7	5
404	R:R:I138	R:R:I218	4.42	No	No	0	9	9
405	R:R:D140	R:R:P141	3.22	No	No	0	7	8
406	R:R:D140	R:R:D143	9.31	No	No	0	7	6
407	R:R:I142	R:R:N146	4.25	No	No	0	6	5
408	R:R:D143	R:R:K147	8.3	No	No	0	6	5
409	R:R:R148	R:R:Y144	5.14	No	No	0	8	8
410	R:R:I157	R:R:T160	3.04	No	Yes	3	8	8
411	R:R:T160	R:R:W161	2.43	Yes	Yes	3	8	9
412	R:R:F165	R:R:I169	6.28	No	No	0	5	6
413	R:R:I167	R:R:Y198	6.04	No	No	0	8	5
414	R:R:I169	R:R:P170	3.39	No	No	0	6	8
415	R:R:I169	R:R:L173	2.85	No	No	0	6	6
416	R:R:P170	R:R:P171	5.84	No	No	0	8	7
417	R:R:P171	R:R:Y195	12.52	No	No	0	7	8
418	R:R:G174	R:R:L173	3.42	No	No	0	5	6
419	R:R:S190	R:R:W175	11.12	No	No	0	6	6
420	R:R:K191	R:R:T188	3	No	No	0	5	5
421	R:R:K191	R:R:P369	3.35	No	Yes	0	5	7
422	R:R:D192	R:R:G194	3.35	No	No	0	6	5
423	R:R:D192	R:R:Y195	3.45	No	No	0	6	8
424	R:R:F370	R:R:H193	10.18	No	No	0	5	4
425	R:R:E372	R:R:H193	2.46	No	No	0	3	4
426	R:R:P369	R:R:T196	6.99	Yes	No	0	7	7
427	R:R:F201	R:R:I197	5.02	No	No	0	5	7
428	R:R:F201	R:R:T200	3.89	No	No	3	5	7
429	R:R:T200	R:R:Y205	4.99	No	Yes	3	7	7
430	R:R:L366	R:R:T200	5.9	No	No	3	7	7
431	R:R:F201	R:R:Y205	10.32	No	Yes	3	5	7
432	R:R:F204	R:R:Y205	5.16	Yes	Yes	3	8	7
433	R:R:F204	R:R:L208	3.65	Yes	No	0	8	7
434	R:R:F204	R:R:F354	6.43	Yes	Yes	0	8	9
435	R:R:F204	R:R:W358	3.01	Yes	Yes	3	8	8
436	R:R:F204	R:R:L359	8.53	Yes	Yes	0	8	7
437	R:R:F204	R:R:F362	24.65	Yes	No	3	8	7
438	R:R:L366	R:R:Y205	5.86	No	Yes	3	7	7
439	R:R:I206	R:R:P207	3.39	No	Yes	0	6	9
440	R:R:L208	R:R:L212	4.15	No	No	0	7	6
441	R:R:I355	R:R:L208	2.85	No	No	0	7	7
442	R:R:L210	R:R:L214	5.54	No	No	0	7	7
443	R:R:M211	R:R:Y215	4.79	No	Yes	29	9	9
444	R:R:F354	R:R:M211	8.71	Yes	No	0	9	9
445	R:R:L212	R:R:M351	2.83	No	No	0	6	8
446	R:R:R217	R:R:V213	5.23	No	No	0	7	5
447	R:R:L347	R:R:Y215	4.69	No	Yes	0	8	9
448	R:R:I350	R:R:Y215	8.46	No	Yes	0	8	9
449	R:R:M351	R:R:Y215	4.79	No	Yes	0	8	9
450	R:R:R220	R:R:R223	6.4	No	No	0	5	7
451	R:R:R223	R:R:R227	10.66	No	No	0	7	6
452	R:R:E340	R:R:R223	6.98	Yes	No	0	8	7
453	R:R:A329	R:R:R333	4.15	No	No	0	5	4
454	R:R:E330	R:R:R333	5.82	No	No	0	4	4
455	R:R:M335	R:R:R339	11.17	No	No	27	4	7
456	R:R:I349	R:R:K345	4.36	No	No	6	7	7
457	R:R:K345	W:W:?1	7.55	No	Yes	6	7	0
458	R:R:I350	R:R:T346	3.04	No	Yes	0	8	8
459	R:R:T346	W:W:?1	9.87	Yes	Yes	0	8	0
460	R:R:I349	R:R:I399	2.94	No	Yes	0	7	8
461	R:R:I349	W:W:?1	3.82	No	Yes	6	7	0
462	R:R:I350	R:R:Y400	3.63	No	Yes	0	8	9
463	R:R:L395	R:R:T353	2.95	No	No	0	6	7
464	R:R:I399	R:R:T353	4.56	Yes	No	0	8	7
465	R:R:I355	R:R:L359	2.85	No	Yes	0	7	7
466	R:R:C357	R:R:N392	9.45	No	Yes	0	8	9
467	R:R:F361	R:R:W358	5.01	No	Yes	0	8	8
468	R:R:F362	R:R:W358	4.01	No	Yes	3	7	8
469	R:R:G389	R:R:W358	8.44	No	Yes	0	8	8
470	R:R:N392	R:R:W358	7.91	Yes	Yes	0	9	8
471	R:R:L359	R:R:P360	3.28	Yes	No	0	7	9
472	R:R:I363	R:R:L359	7.14	No	Yes	0	7	7
473	R:R:F361	R:R:N386	7.25	No	No	0	8	7
474	R:R:L368	R:R:V364	2.98	No	No	15	4	6
475	R:R:M377	R:R:V364	4.56	Yes	No	15	4	6
476	R:R:I385	R:R:V364	3.07	Yes	No	0	6	6
477	R:R:L368	R:R:M377	4.24	No	Yes	15	4	4
478	R:R:F370	R:R:P369	2.89	No	Yes	0	5	7
479	R:R:C371	R:R:S374	3.44	No	No	0	5	5
480	R:R:S373	R:R:S374	3.26	No	No	0	3	5
481	R:R:M377	R:R:P378	3.35	Yes	No	15	4	7
482	R:R:L381	R:R:M377	2.83	No	Yes	15	6	4
483	R:R:L381	R:R:P378	3.28	No	No	15	6	7
484	R:R:I385	R:R:L381	7.14	Yes	No	0	6	6
485	R:R:N386	R:R:Y390	6.98	No	Yes	0	7	8
486	R:R:W387	R:R:Y390	6.75	Yes	Yes	9	8	8
487	R:R:L395	R:R:N392	4.12	No	Yes	0	6	9
488	R:R:N392	R:R:N396	8.17	Yes	No	0	9	9
489	R:R:L394	R:R:L395	2.77	No	No	0	7	6
490	R:R:F403	R:R:V398	2.62	No	No	6	8	6
491	R:R:V398	W:W:?1	5.98	No	Yes	6	6	0
492	R:R:I399	R:R:Y400	3.63	Yes	Yes	0	8	9
493	R:R:F403	R:R:I399	7.54	No	Yes	0	8	8
494	R:R:A401	R:R:F407	4.16	No	Yes	6	8	8
495	R:R:F407	R:R:Y402	4.13	Yes	Yes	6	8	6
496	R:R:F411	R:R:Y402	11.35	Yes	Yes	6	8	6
497	R:R:Y402	W:W:?1	3.92	Yes	Yes	6	6	0
498	R:R:F403	W:W:?1	13.05	No	Yes	6	8	0
499	R:R:D406	R:R:N404	10.77	No	No	0	7	9
500	R:R:F407	R:R:N404	6.04	Yes	No	0	8	9
501	R:R:K405	R:R:Q408	5.42	No	No	0	6	9
502	R:R:K405	W:W:?1	6.61	No	Yes	0	6	0
503	R:R:F407	R:R:F411	8.57	Yes	Yes	6	8	8
504	R:R:K412	R:R:N409	6.99	No	No	0	6	6
505	B:B:D312	R:R:K413	5.53	No	No	0	5	6
506	B:B:K15	B:B:R19	2.48	No	No	0	6	4
507	B:B:N16	B:B:R19	3.62	No	No	0	1	4
508	B:B:I18	B:B:R22	3.76	No	No	0	7	6
509	B:B:D20	B:B:K23	8.3	No	No	0	2	2
510	B:B:D258	B:B:R22	8.34	Yes	No	0	7	6
511	B:B:Q259	B:B:R22	7.01	No	No	0	6	6
512	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
513	B:B:A28	B:B:D27	3.09	No	No	0	4	8
514	B:B:A28	B:B:Q32	3.03	No	No	0	4	1
515	B:B:S31	B:B:T29	3.2	No	No	0	1	3
516	B:B:L30	B:B:T34	2.95	Yes	Yes	11	5	5
517	B:B:L30	B:B:M262	2.83	Yes	No	0	5	4
518	B:B:L30	B:B:L300	4.15	Yes	Yes	11	5	6
519	B:B:L300	B:B:T34	5.9	Yes	Yes	11	6	5
520	B:B:I37	B:B:R283	2.51	No	Yes	0	2	9
521	B:B:D38	B:B:P39	4.83	No	No	0	1	1
522	B:B:I43	B:B:V40	3.07	No	Yes	0	3	3
523	B:B:R283	B:B:V40	9.15	Yes	Yes	11	9	3
524	B:B:D298	B:B:V40	8.76	Yes	Yes	11	9	3
525	B:B:I43	B:B:M45	4.37	No	Yes	0	3	4
526	B:B:L308	B:B:M45	4.24	Yes	Yes	2	7	4
527	B:B:M45	B:B:W339	3.49	Yes	Yes	2	4	9
528	B:B:M45	B:B:N340	4.21	Yes	Yes	2	4	9
529	B:B:K337	B:B:T47	9.01	Yes	No	2	6	3
530	B:B:T47	B:B:W339	8.49	No	Yes	2	3	9
531	B:B:N340	B:B:R48	7.23	Yes	No	0	9	7
532	B:B:R49	B:B:T87	2.59	No	No	0	7	5
533	B:B:R52	B:B:T50	7.76	No	No	0	7	3
534	B:B:K337	B:B:T50	4.5	Yes	No	0	6	3
535	B:B:L51	B:B:W82	6.83	No	Yes	0	9	9
536	B:B:L51	B:B:T87	2.95	No	No	0	9	5
537	B:B:F335	B:B:R52	6.41	Yes	No	0	4	7
538	B:B:G53	B:B:K89	3.49	No	Yes	0	9	9
539	B:B:H54	B:B:I58	6.63	Yes	Yes	7	9	9
540	B:B:H54	B:B:S72	4.18	Yes	Yes	7	9	9
541	B:B:H54	B:B:S74	12.55	Yes	No	7	9	9
542	B:B:D76	B:B:H54	2.52	Yes	Yes	7	9	9
543	B:B:H54	B:B:I80	13.26	Yes	Yes	7	9	8
544	B:B:H54	B:B:W82	7.41	Yes	Yes	7	9	9
545	B:B:A56	B:B:D76	4.63	No	Yes	0	7	9
546	B:B:K57	B:B:Y59	13.14	No	Yes	1	9	8
547	B:B:K57	B:B:W332	16.24	No	Yes	1	9	9
548	B:B:I58	B:B:S72	6.19	Yes	Yes	7	9	9
549	B:B:I58	B:B:S74	3.1	Yes	No	7	9	9
550	B:B:I58	B:B:L336	4.28	Yes	Yes	7	9	7
551	B:B:Q75	B:B:Y59	24.8	No	Yes	1	9	8
552	B:B:W332	B:B:Y59	4.82	Yes	Yes	1	9	8
553	B:B:A60	B:B:C103	3.61	No	No	0	7	8
554	B:B:M61	B:B:W63	5.82	No	Yes	7	6	7
555	B:B:L70	B:B:M61	4.24	No	No	7	5	6
556	B:B:M61	B:B:S72	4.6	No	Yes	7	6	9
557	B:B:H62	B:B:Y105	4.36	No	Yes	0	6	6
558	B:B:H62	B:B:R150	4.51	No	Yes	0	6	6
559	B:B:L70	B:B:W63	10.25	No	Yes	7	5	7
560	B:B:S84	B:B:W63	6.18	No	Yes	0	5	7
561	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
562	B:B:T321	B:B:W63	9.7	No	Yes	0	7	7
563	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
564	B:B:G64	B:B:Y105	2.9	No	Yes	0	5	6
565	B:B:D66	B:B:R68	7.15	No	Yes	0	8	5
566	B:B:S67	B:B:T321	4.8	No	No	0	5	7
567	B:B:D323	B:B:S67	2.94	No	No	0	7	5
568	B:B:L69	B:B:R68	2.43	No	Yes	2	5	5
569	B:B:D83	B:B:R68	9.53	Yes	Yes	2	8	5
570	B:B:R68	B:B:Y85	8.23	Yes	No	2	5	4
571	B:B:I81	B:B:L69	4.28	Yes	No	2	7	5
572	B:B:D83	B:B:L69	2.71	Yes	No	2	8	5
573	B:B:L70	B:B:W82	3.42	No	Yes	7	5	9
574	B:B:L79	B:B:V71	2.98	Yes	Yes	2	7	8
575	B:B:I81	B:B:V71	4.61	Yes	Yes	2	7	8
576	B:B:V71	B:B:Y105	5.05	Yes	Yes	2	8	6
577	B:B:V112	B:B:V71	4.81	No	Yes	2	8	8
578	B:B:S72	B:B:W82	6.18	Yes	Yes	7	9	9
579	B:B:L336	B:B:S72	3	Yes	Yes	7	7	9
580	B:B:A73	B:B:V100	3.39	No	No	0	9	9
581	B:B:A73	B:B:C103	3.61	No	No	0	9	8
582	B:B:D76	B:B:S74	5.89	Yes	No	7	9	9
583	B:B:Q75	B:B:W99	4.38	No	Yes	1	9	9
584	B:B:D76	B:B:K78	6.91	Yes	No	0	9	8
585	B:B:G77	B:B:L95	3.42	No	Yes	0	8	8
586	B:B:I93	B:B:L79	9.99	Yes	Yes	0	7	7
587	B:B:L79	B:B:L95	4.15	Yes	Yes	2	7	8
588	B:B:C114	B:B:L79	3.17	Yes	Yes	2	8	7
589	B:B:I80	B:B:W82	16.44	Yes	Yes	7	8	9
590	B:B:I81	B:B:V90	3.07	Yes	No	2	7	5
591	B:B:H91	B:B:I81	3.98	No	Yes	2	5	7
592	B:B:I81	B:B:L126	4.28	Yes	Yes	2	7	5
593	B:B:K89	B:B:W82	6.96	Yes	Yes	0	9	9
594	B:B:L336	B:B:W82	3.42	Yes	Yes	7	7	9
595	B:B:D83	B:B:Y85	5.75	Yes	No	2	8	4
596	B:B:D83	B:B:T86	7.23	Yes	No	0	8	6
597	B:B:N88	B:B:T86	11.7	No	No	0	7	6
598	B:B:H91	B:B:V90	5.54	No	No	2	5	5
599	B:B:H91	B:B:L126	2.57	No	Yes	2	5	5
600	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
601	B:B:I93	B:B:Y124	8.46	Yes	Yes	0	7	6
602	B:B:I93	B:B:V133	7.68	Yes	No	0	7	4
603	B:B:C114	B:B:L95	4.76	Yes	Yes	2	8	8
604	B:B:L95	B:B:Y124	7.03	Yes	Yes	2	8	6
605	B:B:E138	B:B:R96	5.82	No	No	0	6	6
606	B:B:D118	B:B:S97	8.83	No	No	0	9	8
607	B:B:S98	B:B:W99	8.65	No	Yes	0	8	9
608	B:B:L117	B:B:W99	7.97	No	Yes	1	9	9
609	B:B:G116	B:B:M101	3.49	No	No	0	9	9
610	B:B:C148	B:B:T102	5.07	No	No	0	6	8
611	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
612	B:B:V112	B:B:Y105	2.52	No	Yes	2	8	6
613	B:B:L126	B:B:Y105	3.52	Yes	Yes	2	5	6
614	B:B:A106	B:B:F151	2.77	No	Yes	0	6	9
615	B:B:N110	B:B:S108	4.47	No	No	0	4	6
616	B:B:K127	B:B:N110	2.8	No	No	0	4	4
617	B:B:N125	B:B:Y111	9.3	No	Yes	0	4	4
618	B:B:D154	B:B:Y111	5.75	No	Yes	0	6	4
619	B:B:L126	B:B:V112	4.47	Yes	No	2	5	8
620	B:B:A113	B:B:F151	5.55	No	Yes	0	9	9
621	B:B:C114	B:B:Y124	4.03	Yes	Yes	2	8	6
622	B:B:D118	B:B:I120	8.4	No	No	0	9	6
623	B:B:G144	B:B:N119	3.39	No	No	0	8	9
624	B:B:E138	B:B:I120	9.56	No	No	0	6	6
625	B:B:C121	B:B:C149	7.28	No	No	0	8	8
626	B:B:S122	B:B:Y124	7.63	No	Yes	0	8	6
627	B:B:E138	B:B:S122	2.87	No	No	0	6	8
628	B:B:I123	B:B:R137	2.51	Yes	Yes	16	6	5
629	B:B:F151	B:B:I123	5.02	Yes	Yes	16	9	6
630	B:B:I123	B:B:I157	2.94	Yes	Yes	16	6	7
631	B:B:I123	B:B:I171	2.94	Yes	No	16	6	6
632	B:B:V135	B:B:Y124	3.79	No	Yes	0	4	6
633	B:B:N125	B:B:T128	4.39	No	No	0	4	3
634	B:B:N125	B:B:S136	2.98	No	No	0	4	4
635	B:B:E130	B:B:T128	2.82	No	No	0	3	3
636	B:B:E130	B:B:N132	3.94	No	No	0	3	3
637	B:B:L139	B:B:R137	3.64	No	Yes	0	9	5
638	B:B:I171	B:B:R137	3.76	No	Yes	16	6	5
639	B:B:G174	B:B:R137	3	No	Yes	0	4	5
640	B:B:L139	B:B:W169	13.67	No	Yes	0	9	8
641	B:B:G141	B:B:W169	2.81	No	Yes	0	5	8
642	B:B:H142	B:B:L146	3.86	Yes	No	13	9	7
643	B:B:H142	B:B:T159	5.48	Yes	No	13	9	9
644	B:B:H142	B:B:S161	16.74	Yes	No	13	9	9
645	B:B:H142	B:B:T165	2.74	Yes	No	0	9	7
646	B:B:A167	B:B:H142	2.93	No	Yes	13	4	9
647	B:B:H142	B:B:W169	8.46	Yes	Yes	13	9	8
648	B:B:D163	B:B:T143	5.78	No	No	0	9	5
649	B:B:G162	B:B:Y145	4.35	No	Yes	0	9	8
650	B:B:D186	B:B:Y145	8.05	No	Yes	1	9	8
651	B:B:M188	B:B:Y145	3.59	Yes	Yes	1	8	8
652	B:B:L146	B:B:S161	3	No	No	13	7	9
653	B:B:M188	B:B:S147	3.07	Yes	No	0	8	9
654	B:B:C148	B:B:R150	6.96	No	Yes	0	6	6
655	B:B:C149	B:B:I157	4.91	No	Yes	0	8	7
656	B:B:C149	B:B:T159	3.38	No	No	0	8	9
657	B:B:L190	B:B:R150	2.43	Yes	Yes	4	5	6
658	B:B:L192	B:B:R150	2.43	Yes	Yes	4	5	6
659	B:B:F151	B:B:I157	6.28	Yes	Yes	16	9	7
660	B:B:D153	B:B:L152	2.71	No	Yes	0	5	3
661	B:B:L152	B:B:V158	5.96	Yes	No	4	3	5
662	B:B:L152	B:B:L192	6.92	Yes	Yes	4	3	5
663	B:B:L152	B:B:V213	2.98	Yes	No	0	3	4
664	B:B:D170	B:B:N155	13.46	No	No	0	9	3
665	B:B:L168	B:B:Q156	3.99	Yes	No	0	6	5
666	B:B:I157	B:B:I171	4.42	Yes	No	16	7	6
667	B:B:L192	B:B:V158	4.47	Yes	No	4	5	5
668	B:B:T159	B:B:W169	7.28	No	Yes	13	9	8
669	B:B:C166	B:B:S160	3.44	Yes	No	0	8	6
670	B:B:S160	B:B:V187	6.46	No	Yes	0	6	9
671	B:B:L190	B:B:S160	3	Yes	No	0	5	6
672	B:B:G162	B:B:S161	3.71	No	No	0	9	9
673	B:B:D163	B:B:T165	8.67	No	No	0	9	7
674	B:B:T165	B:B:T181	3.14	No	No	0	7	2
675	B:B:C166	B:B:F180	4.19	Yes	Yes	4	8	7
676	B:B:C166	B:B:F199	2.79	Yes	Yes	4	8	9
677	B:B:C166	B:B:S201	3.44	Yes	Yes	4	8	9
678	B:B:A167	B:B:W169	3.89	No	Yes	13	4	8
679	B:B:L168	B:B:T177	4.42	Yes	No	4	6	4
680	B:B:L168	B:B:T178	5.9	Yes	No	4	6	4
681	B:B:L168	B:B:V213	2.98	Yes	No	0	6	4
682	B:B:Q176	B:B:W169	18.62	No	Yes	0	4	8
683	B:B:D170	B:B:T173	7.23	No	No	0	9	5
684	B:B:E172	B:B:T173	4.23	No	No	0	6	5
685	B:B:Q175	B:B:T173	7.09	No	No	0	4	5
686	B:B:Q176	B:B:T179	5.67	No	No	0	4	4
687	B:B:T177	B:B:T178	4.71	No	No	4	4	4
688	B:B:F180	B:B:T178	6.49	Yes	No	4	7	4
689	B:B:F180	B:B:F199	5.36	Yes	Yes	4	7	9
690	B:B:F180	B:B:W211	20.04	Yes	Yes	4	7	8
691	B:B:F180	B:B:G216	4.52	Yes	No	0	7	4
692	B:B:H183	B:B:V187	6.92	Yes	Yes	4	9	9
693	B:B:H183	B:B:S201	5.58	Yes	Yes	4	9	9
694	B:B:A203	B:B:H183	5.85	No	Yes	4	8	9
695	B:B:H183	B:B:K209	13.1	Yes	Yes	4	9	6
696	B:B:H183	B:B:W211	5.29	Yes	Yes	4	9	8
697	B:B:D205	B:B:T184	10.12	No	No	0	9	3
698	B:B:D186	B:B:M188	2.77	No	Yes	1	9	8
699	B:B:C204	B:B:D186	4.67	Yes	No	1	7	9
700	B:B:S201	B:B:V187	3.23	Yes	Yes	4	9	9
701	B:B:A203	B:B:V187	3.39	No	Yes	4	8	9
702	B:B:I232	B:B:S189	4.64	Yes	No	0	8	7
703	B:B:L190	B:B:L192	2.77	Yes	Yes	4	5	5
704	B:B:F199	B:B:L190	8.53	Yes	Yes	4	9	5
705	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
706	B:B:F199	B:B:L192	2.44	Yes	Yes	4	9	5
707	B:B:A193	B:B:D195	3.09	No	No	0	4	5
708	B:B:A193	B:B:F234	2.77	No	Yes	0	4	5
709	B:B:D195	B:B:R197	8.34	No	No	0	5	5
710	B:B:R197	B:B:R214	3.2	No	No	0	5	9
711	B:B:L198	B:B:L210	8.3	No	Yes	0	3	5
712	B:B:F234	B:B:L198	2.44	Yes	No	0	5	3
713	B:B:F199	B:B:W211	9.02	Yes	Yes	4	9	8
714	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
715	B:B:L210	B:B:V200	4.47	Yes	Yes	0	5	6
716	B:B:I232	B:B:V200	6.14	Yes	Yes	5	8	6
717	B:B:F234	B:B:V200	9.18	Yes	Yes	0	5	6
718	B:B:F241	B:B:V200	2.62	Yes	Yes	5	6	6
719	B:B:S201	B:B:W211	6.18	Yes	Yes	4	9	8
720	B:B:G202	B:B:I229	3.53	No	No	0	6	7
721	B:B:C204	B:B:D228	12.45	Yes	No	1	7	9
722	B:B:S207	B:B:T221	3.2	No	No	0	5	7
723	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
724	B:B:K209	B:B:W211	4.64	Yes	Yes	4	6	8
725	B:B:C218	B:B:K209	4.85	No	Yes	4	5	6
726	B:B:K209	B:B:T221	4.5	Yes	No	0	6	7
727	B:B:L210	B:B:R219	3.64	Yes	No	0	5	5
728	B:B:L210	B:B:L255	4.15	Yes	No	0	5	6
729	B:B:C218	B:B:W211	6.53	No	Yes	4	5	8
730	B:B:D212	B:B:E215	9.09	No	No	0	9	3
731	B:B:E215	B:B:R214	12.79	No	No	0	3	9
732	B:B:M217	B:B:R219	9.93	No	No	0	3	5
733	B:B:F222	B:B:Q220	9.37	Yes	No	5	8	7
734	B:B:D258	B:B:Q220	10.44	Yes	No	5	7	7
735	B:B:F222	B:B:F241	5.36	Yes	Yes	5	8	6
736	B:B:F222	B:B:F253	4.29	Yes	Yes	5	8	6
737	B:B:F222	B:B:L255	2.44	Yes	No	5	8	6
738	B:B:D258	B:B:F222	7.17	Yes	Yes	5	7	8
739	B:B:G224	B:B:R251	3	No	Yes	0	6	8
740	B:B:H225	B:B:I229	6.63	Yes	No	0	9	7
741	B:B:H225	B:B:T243	5.48	Yes	Yes	5	9	8
742	B:B:H225	B:B:S245	11.16	Yes	No	0	9	9
743	B:B:H225	B:B:T249	2.74	Yes	Yes	5	9	6
744	B:B:H225	B:B:R251	16.93	Yes	Yes	5	9	8
745	B:B:F253	B:B:H225	4.53	Yes	Yes	5	6	9
746	B:B:D247	B:B:E226	3.9	No	No	0	9	3
747	B:B:D246	B:B:S227	7.36	No	No	0	9	6
748	B:B:D247	B:B:S227	5.89	No	No	0	9	6
749	B:B:D228	B:B:D246	2.66	No	No	0	9	9
750	B:B:D246	B:B:N230	8.08	No	No	0	9	9
751	B:B:A231	B:B:V276	3.39	No	No	0	5	6
752	B:B:F241	B:B:I232	8.79	Yes	Yes	5	6	8
753	B:B:I232	B:B:T243	4.56	Yes	Yes	5	8	8
754	B:B:C233	B:B:F278	2.79	No	Yes	0	3	7
755	B:B:F235	B:B:P236	10.11	Yes	Yes	14	6	7
756	B:B:F235	B:B:F278	7.5	Yes	Yes	14	6	7
757	B:B:F235	B:B:G282	3.01	Yes	No	14	6	9
758	B:B:F278	B:B:P236	2.89	Yes	Yes	14	7	7
759	B:B:G282	B:B:P236	4.06	No	Yes	14	9	7
760	B:B:N237	B:B:N239	10.9	No	No	0	5	2
761	B:B:N239	B:B:R256	4.82	No	No	0	2	9
762	B:B:F241	B:B:T243	2.59	Yes	Yes	5	6	8
763	B:B:F241	B:B:F253	9.65	Yes	Yes	5	6	6
764	B:B:F241	B:B:L255	4.87	Yes	No	5	6	6
765	B:B:A242	B:B:F278	4.16	No	Yes	0	4	7
766	B:B:F253	B:B:T243	7.78	Yes	Yes	5	6	8
767	B:B:C250	B:B:G244	3.92	No	No	0	8	5
768	B:B:G244	B:B:I273	3.53	No	Yes	0	5	6
769	B:B:D247	B:B:T249	2.89	No	Yes	0	9	6
770	B:B:A248	B:B:I269	4.87	No	Yes	0	5	4
771	B:B:R251	B:B:T249	5.17	Yes	Yes	5	8	6
772	B:B:S265	B:B:T249	3.2	No	Yes	0	2	6
773	B:B:C250	B:B:Y264	2.69	No	Yes	0	8	5
774	B:B:F253	B:B:R251	5.34	Yes	Yes	5	6	8
775	B:B:E260	B:B:R251	18.61	No	Yes	5	6	8
776	B:B:R251	B:B:T263	3.88	Yes	No	5	8	1
777	B:B:L252	B:B:L261	4.15	No	No	0	7	5
778	B:B:E260	B:B:F253	5.83	No	Yes	5	6	6
779	B:B:D254	B:B:R256	4.76	Yes	No	0	9	9
780	B:B:A257	B:B:D254	4.63	No	Yes	0	7	9
781	B:B:D254	B:B:L261	2.71	Yes	No	0	9	5
782	B:B:E260	B:B:T263	2.82	No	No	5	6	1
783	B:B:M262	B:B:Y264	14.37	No	Yes	0	4	5
784	B:B:L285	B:B:Y264	4.69	No	Yes	0	6	5
785	B:B:W297	B:B:Y264	3.86	Yes	Yes	0	8	5
786	B:B:H266	B:B:N268	2.55	No	No	0	4	4
787	B:B:H266	B:B:I269	2.65	No	Yes	10	4	4
788	B:B:H266	B:B:R304	12.41	No	Yes	10	4	5
789	B:B:I269	B:B:Y289	10.88	Yes	Yes	10	4	7
790	B:B:I269	B:B:R304	2.51	Yes	Yes	10	4	5
791	B:B:C271	B:B:D290	9.34	No	No	0	5	6
792	B:B:C271	B:B:D291	7.78	No	No	0	5	8
793	B:B:D290	B:B:G272	3.35	No	No	0	6	4
794	B:B:I273	B:B:V276	3.07	Yes	No	0	6	6
795	B:B:A287	B:B:I273	3.25	No	Yes	10	6	6
796	B:B:I273	B:B:Y289	7.25	Yes	Yes	10	6	7
797	B:B:S275	B:B:T274	3.2	No	No	0	8	8
798	B:B:L318	B:B:S275	3	No	No	0	6	8
799	B:B:L318	B:B:S277	4.5	No	No	0	6	5
800	B:B:F278	B:B:L285	4.87	Yes	No	0	7	6
801	B:B:L284	B:B:S279	4.5	No	No	0	5	9
802	B:B:D298	B:B:R283	8.34	Yes	Yes	11	9	9
803	B:B:L284	B:B:V296	4.47	No	Yes	0	5	5
804	B:B:L286	B:B:V296	4.47	No	Yes	0	7	5
805	B:B:L286	B:B:V327	4.47	No	No	0	7	6
806	B:B:A287	B:B:Y289	4	No	Yes	10	6	7
807	B:B:G288	B:B:V315	3.68	No	No	0	7	7
808	B:B:N295	B:B:Y289	5.81	No	Yes	10	6	7
809	B:B:W297	B:B:Y289	8.68	Yes	Yes	10	8	7
810	B:B:D290	B:B:R314	15.48	No	No	0	6	8
811	B:B:F292	B:B:N293	4.83	No	No	0	4	5
812	B:B:N293	B:B:V307	4.43	No	No	0	5	3
813	B:B:A309	B:B:N293	3.13	No	No	0	3	5
814	B:B:C294	B:B:L308	4.76	No	Yes	0	5	7
815	B:B:C294	B:B:V315	3.42	No	No	0	5	7
816	B:B:C294	B:B:T329	5.07	No	Yes	0	5	8
817	B:B:N295	B:B:W297	13.56	No	Yes	10	6	8
818	B:B:N295	B:B:R304	15.67	No	Yes	10	6	5
819	B:B:L308	B:B:V296	2.98	Yes	Yes	0	7	5
820	B:B:R304	B:B:W297	13.99	Yes	Yes	10	5	8
821	B:B:D298	B:B:L300	5.43	Yes	Yes	11	9	6
822	B:B:D298	B:B:K301	5.53	Yes	No	0	9	5
823	B:B:D303	B:B:K301	8.3	No	No	0	2	5
824	B:B:R304	B:B:V307	2.62	Yes	No	0	5	3
825	B:B:L308	B:B:W339	22.78	Yes	Yes	2	7	9
826	B:B:H311	B:B:V315	5.54	Yes	No	0	9	7
827	B:B:H311	B:B:T329	6.85	Yes	Yes	0	9	8
828	B:B:H311	B:B:S331	12.55	Yes	No	0	9	9
829	B:B:H311	B:B:K337	2.62	Yes	Yes	0	9	6
830	B:B:D312	B:B:D333	7.98	No	No	0	5	9
831	B:B:N313	B:B:W332	9.04	No	Yes	0	7	9
832	B:B:R314	B:B:W332	18.99	No	Yes	0	8	9
833	B:B:C317	B:B:S316	3.44	No	No	0	7	9
834	B:B:S316	B:B:W332	3.71	No	Yes	0	9	9
835	B:B:L318	B:B:T329	2.95	No	Yes	0	6	8
836	B:B:V320	B:B:V327	4.81	No	No	0	7	6
837	B:B:D323	B:B:M325	2.77	No	Yes	0	7	5
838	B:B:M325	B:B:N340	2.8	Yes	Yes	2	5	9
839	B:B:A326	B:B:N340	6.25	No	Yes	2	7	9
840	B:B:V327	B:B:W339	2.45	No	Yes	0	6	9
841	B:B:T329	B:B:W339	2.43	Yes	Yes	0	8	9
842	B:B:G330	B:B:L336	3.42	No	Yes	0	5	7
843	B:B:D333	B:B:F335	14.33	No	Yes	0	9	4
844	B:B:F335	B:B:S334	2.64	Yes	No	0	4	4
845	B:B:K337	B:B:W339	3.48	Yes	Yes	2	6	9
846	B:B:I123	B:B:Y111	2.42	Yes	Yes	0	6	4
847	B:B:M101	B:B:Y59	2.39	No	Yes	0	9	8
848	B:B:M101	B:B:Y145	2.39	No	Yes	0	9	8
849	R:R:L166	R:R:Y198	2.34	No	No	0	5	5
850	A:A:E43	A:A:R242	2.33	No	Yes	0	9	9
851	R:R:E340	R:R:F219	2.33	Yes	No	0	8	6
852	B:B:N110	B:B:Y111	2.33	No	Yes	0	4	4
853	R:R:Q36	R:R:Y35	2.25	No	No	0	4	4
854	A:A:E275	A:A:Y296	2.24	No	Yes	0	5	4
855	A:A:R205	A:A:R208	2.13	No	Yes	0	9	9
856	R:R:C49	W:W:?1	2.12	No	Yes	0	5	0
857	B:B:G115	B:B:G116	2.11	No	No	0	9	9
858	B:B:G144	B:B:G162	2.11	No	No	0	8	9
859	B:B:G324	G:G:P49	2.03	No	No	0	9	7
860	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
861	B:B:C317	B:B:G330	1.96	No	No	0	7	5
862	A:A:A41	A:A:G42	1.95	No	No	0	7	8
863	R:R:A79	R:R:G76	1.95	No	No	0	9	6
864	B:B:A309	B:B:G310	1.95	No	No	0	3	5
865	B:B:A106	B:B:P107	1.87	No	No	0	6	6
866	B:B:A193	B:B:P194	1.87	No	No	0	4	4
867	B:B:G306	B:B:V296	1.84	No	Yes	0	4	5
868	B:B:G324	B:B:V320	1.84	No	No	0	9	7
869	B:B:G131	B:B:T128	1.82	No	No	0	4	3
870	B:B:G185	B:B:T164	1.82	No	No	0	5	6
871	B:B:G182	B:B:T181	1.82	No	No	0	6	2
872	B:B:G185	B:B:T184	1.82	No	No	0	5	3
873	B:B:G224	B:B:T223	1.82	No	No	0	6	2
874	B:B:A104	B:B:A113	1.79	No	No	0	7	9
875	R:R:G202	R:R:I206	1.76	No	No	0	5	6
876	R:R:G352	R:R:I355	1.76	No	No	0	6	7
877	G:G:P53	G:G:T52	1.75	No	No	0	8	4
878	R:R:P150	R:R:T149	1.75	No	No	0	5	8
879	R:R:G382	R:R:M377	1.75	No	Yes	0	4	4
880	B:B:P107	B:B:T65	1.75	No	No	0	6	1
881	A:A:G202	A:A:K46	1.74	No	Yes	0	9	9
882	A:A:C325	A:A:S326	1.72	No	No	0	7	9
883	A:A:G27	B:B:L55	1.71	No	No	0	5	6
884	R:R:G44	R:R:L43	1.71	No	Yes	0	4	7
885	R:R:G53	R:R:L52	1.71	No	No	0	9	4
886	R:R:A114	R:R:S168	1.71	No	No	0	7	8
887	R:R:G348	R:R:L347	1.71	No	No	0	7	8
888	R:R:C371	R:R:V367	1.71	No	No	0	5	6
889	R:R:G389	R:R:L388	1.71	No	No	0	8	8
890	B:B:C103	B:B:V71	1.71	No	Yes	0	8	8
891	B:B:C114	B:B:V100	1.71	Yes	No	0	8	9
892	A:A:G45	A:A:N269	1.7	No	Yes	0	9	9
893	A:A:G183	B:B:N119	1.7	No	No	0	9	9
894	R:R:A79	R:R:V58	1.7	No	No	0	9	7
895	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
896	A:A:C325	A:A:T327	1.69	No	No	0	7	8
897	R:R:I385	R:R:P360	1.69	Yes	No	0	6	9
898	R:R:A203	R:R:T121	1.68	No	Yes	0	8	8
899	R:R:A129	R:R:T160	1.68	No	Yes	0	8	8
900	R:R:M172	R:R:P171	1.68	No	No	0	6	7
901	R:R:A222	R:R:T343	1.68	No	No	0	8	8
902	A:A:C286	A:A:I285	1.64	Yes	No	0	6	3
903	R:R:L90	R:R:P91	1.64	Yes	No	0	8	9
904	R:R:L368	R:R:P369	1.64	No	Yes	0	4	7
905	A:A:I19	B:B:A92	1.62	No	No	0	9	6
906	A:A:A220	A:A:I265	1.62	No	Yes	0	8	8
907	G:G:S31	G:G:V30	1.62	No	No	0	9	8
908	R:R:S40	R:R:V98	1.62	No	Yes	0	5	6
909	R:R:A401	R:R:I75	1.62	No	No	0	8	8
910	R:R:A336	R:R:I226	1.62	No	No	0	5	6
911	B:B:A92	B:B:I80	1.62	No	Yes	0	6	8
912	B:B:A140	B:B:I120	1.62	No	No	0	5	6
913	R:R:A336	R:R:K332	1.61	No	No	0	5	6
914	B:B:A302	B:B:M262	1.61	No	No	0	2	4
915	R:R:V58	R:R:V80	1.6	No	No	0	7	7
916	B:B:S31	B:B:T34	1.6	No	Yes	0	1	5
917	A:A:T187	A:A:V185	1.59	No	No	0	6	5
918	R:R:T39	R:R:V98	1.59	No	Yes	0	5	6
919	R:R:T121	R:R:V117	1.59	Yes	No	0	8	8
920	B:B:A240	G:G:L37	1.58	No	No	0	6	7
921	R:R:A59	R:R:L63	1.58	No	No	0	5	6
922	B:B:A240	B:B:L252	1.58	No	No	0	6	7
923	B:B:A299	B:B:L285	1.58	No	No	0	5	6
924	B:B:A299	B:B:L300	1.58	No	Yes	0	5	6
925	A:A:N347	R:R:A137	1.56	No	No	0	8	8
926	A:A:A30	A:A:D26	1.54	No	No	0	3	5
927	G:G:A45	G:G:D48	1.54	No	Yes	0	4	9
928	R:R:A71	R:R:D133	1.54	No	No	0	8	9
929	R:R:I363	R:R:V367	1.54	No	No	0	7	6
930	B:B:A24	B:B:D20	1.54	No	No	0	3	2
931	A:A:K280	A:A:S281	1.53	No	No	0	1	7
932	R:R:A383	R:R:Q97	1.52	No	No	0	6	7
933	R:R:F219	R:R:G216	1.51	No	No	0	6	3
934	R:R:K342	R:R:T346	1.5	No	Yes	0	8	8
935	B:B:L261	G:G:V30	1.49	No	No	0	5	8
936	R:R:L43	R:R:V98	1.49	Yes	Yes	9	7	6
937	R:R:L95	R:R:V98	1.49	No	Yes	9	6	6
938	R:R:L99	R:R:V98	1.49	No	Yes	9	5	6
939	A:A:V13	B:B:N88	1.48	No	No	0	3	7
940	R:R:N146	R:R:V145	1.48	No	No	0	5	6
941	A:A:D9	A:A:S6	1.47	No	No	0	4	7
942	G:G:L51	G:G:T52	1.47	No	No	0	6	4
943	R:R:L99	R:R:T103	1.47	No	No	0	5	5
944	R:R:L104	R:R:T103	1.47	No	No	0	7	5
945	R:R:D192	R:R:S190	1.47	No	No	0	6	6
946	R:R:I384	R:R:I385	1.47	No	Yes	0	4	6
947	A:A:D9	A:A:V13	1.46	No	No	0	4	3
948	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
949	A:A:D328	A:A:T327	1.45	No	No	0	9	8
950	B:B:D153	B:B:T196	1.45	No	No	0	5	1
951	B:B:D170	B:B:T177	1.45	No	No	0	9	4
952	G:G:K20	G:G:M21	1.44	No	No	0	6	1
953	G:G:K29	G:G:K32	1.44	No	No	0	4	5
954	R:R:I414	R:R:L63	1.43	No	No	0	7	6
955	R:R:I163	R:R:L159	1.43	No	No	0	5	3
956	R:R:E340	R:R:V344	1.43	Yes	No	0	8	8
957	A:A:K314	R:R:N328	1.4	No	No	0	3	3
958	R:R:K405	R:R:N409	1.4	No	No	0	6	6
959	B:B:K301	B:B:N35	1.4	No	No	0	5	1
960	A:A:P288	A:A:Y287	1.39	No	Yes	0	5	7
961	B:B:L14	G:G:L19	1.38	No	No	0	8	9
962	R:R:A338	R:R:R341	1.38	No	No	0	5	6
963	R:R:E340	R:R:I226	1.37	Yes	No	0	8	6
964	R:R:N325	R:R:N328	1.36	No	No	0	5	3
965	A:A:E33	A:A:K29	1.35	No	No	0	6	1
966	A:A:D200	A:A:N47	1.35	No	No	0	9	9
967	A:A:E276	A:A:K280	1.35	No	No	0	5	1
968	B:B:K280	G:G:E47	1.35	No	No	0	1	3
969	A:A:E276	A:A:L273	1.33	No	No	0	5	6
970	G:G:E22	G:G:L19	1.33	No	No	0	9	9
971	R:R:A186	R:R:Y96	1.33	No	No	0	4	6
972	B:B:L14	B:B:Q17	1.33	No	No	0	8	4
973	R:R:R151	R:R:T149	1.29	No	No	0	6	8
974	A:A:H244	A:A:N241	1.28	No	No	0	4	9
975	A:A:F189	A:A:K54	1.24	Yes	No	0	9	7
976	A:A:E33	A:A:H195	1.23	No	No	0	6	4
977	A:A:R32	R:R:N146	1.21	No	No	0	4	5
978	A:A:E28	A:A:R24	1.16	No	No	0	4	3
979	B:B:E130	B:B:R134	1.16	No	No	0	3	3
980	B:B:R48	G:G:R62	1.07	No	No	0	7	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:L38	5.2325	4	8	8
2	A:A:L39	4.1225	4	1	9
3	A:A:K46	4.828	5	8	9
4	A:A:M53	6.3525	4	0	8
5	A:A:I184	4.74	4	1	9
6	A:A:F189	5.9875	4	0	9
7	A:A:F191	7.39	4	17	5
8	A:A:F196	7.585	4	18	7
9	A:A:K197	6.925	4	1	6
10	A:A:F199	6.492	5	1	5
11	A:A:E207	4.14	4	1	9
12	A:A:R208	5	4	0	9
13	A:A:W211	5.492	5	1	9
14	A:A:F215	4.96	6	1	9
15	A:A:I221	4.398	5	1	8
16	A:A:I222	3.145	4	8	7
17	A:A:F223	5.385	6	1	9
18	A:A:R242	7.83	4	21	9
19	A:A:F250	6.86	4	0	9
20	A:A:I253	4.2175	4	1	8
21	A:A:N256	6.38	4	1	8
22	A:A:W258	9.18	4	1	5
23	A:A:F259	6.57	5	1	9
24	A:A:I265	2.818	5	8	8
25	A:A:F267	4.31333	6	8	9
26	A:A:L268	4.6475	4	1	8
27	A:A:N269	5.4425	4	0	9
28	A:A:F274	6.296	5	19	9
29	A:A:C286	4.245	4	0	6
30	A:A:Y287	5.66167	6	22	7
31	A:A:Y296	4.078	5	19	4
32	A:A:F307	3.996	5	1	8
33	A:A:N331	6.6425	4	8	8
34	A:A:F336	4.2825	4	17	8
35	A:A:L348	4.5	4	0	9
36	A:A:L353	4.7	5	0	7
37	A:A:F354	8.462	5	0	5
38	G:G:M38	4.01	4	11	4
39	G:G:Y40	6.325	4	14	6
40	G:G:D48	4.054	5	0	9
41	G:G:V54	4.9075	4	2	6
42	G:G:N59	5.912	5	2	9
43	G:G:F61	5.57857	7	2	8
44	R:R:L43	4.545	4	9	7
45	R:R:N54	5.3675	4	3	9
46	R:R:V57	4.29	5	6	9
47	R:R:L67	3.5725	4	0	8
48	R:R:L74	4.2525	4	0	8
49	R:R:L78	3.61	5	3	9
50	R:R:D82	3.98	5	3	9
51	R:R:S86	3.1575	4	0	8
52	R:R:L90	3.318	5	0	8
53	R:R:V98	1.536	5	9	6
54	R:R:W102	5.61833	6	12	9
55	R:R:F112	5.415	4	0	6
56	R:R:T121	3.388	5	0	8
57	R:R:I124	4.18	4	3	8
58	R:R:W125	4.518	5	3	7
59	R:R:H126	7.20286	7	3	8
60	R:R:L127	5.865	4	0	8
61	R:R:I130	4.2325	4	0	9
62	R:R:Y135	8.592	5	0	9
63	R:R:T160	4.106	5	3	8
64	R:R:W161	6.1825	4	3	9
65	R:R:F204	8.57167	6	3	8
66	R:R:Y205	6.5825	4	3	7
67	R:R:P207	4.3275	4	3	9
68	R:R:Y215	5.346	5	29	9
69	R:R:E340	3.0275	4	0	8
70	R:R:T346	4.34	4	0	8
71	R:R:F354	5.3375	4	0	9
72	R:R:W358	5.80714	7	3	8
73	R:R:L359	5.45	4	0	7
74	R:R:P369	3.7175	4	0	7
75	R:R:M377	3.346	5	15	4
76	R:R:I385	3.3425	4	0	6
77	R:R:W387	5.75	5	9	8
78	R:R:Y390	6.746	5	9	8
79	R:R:N392	7.4125	4	0	9
80	R:R:I399	4.6675	4	0	8
81	R:R:Y400	4.79	4	0	9
82	R:R:Y402	5.00667	6	6	6
83	R:R:F407	4.95143	7	6	8
84	R:R:F411	6.7175	4	6	8
85	B:B:L30	3.665	4	11	5
86	B:B:T34	3.365	4	11	5
87	B:B:V40	5.67	4	11	3
88	B:B:M45	4.0775	4	2	4
89	B:B:H54	7.75833	6	7	9
90	B:B:I58	5.05	4	7	9
91	B:B:Y59	10.374	5	1	8
92	B:B:W63	6.44167	6	7	7
93	B:B:R68	6.835	4	2	5
94	B:B:V71	3.832	5	2	8
95	B:B:S72	4.83	5	7	9
96	B:B:D76	4.9875	4	7	9
97	B:B:L79	5.0725	4	2	7
98	B:B:I80	8.5425	4	7	8
99	B:B:I81	4.044	5	2	7
100	B:B:W82	7.23714	7	7	9
101	B:B:D83	6.305	4	2	8
102	B:B:K89	5.96	4	0	9
103	B:B:I93	7.38	4	0	7
104	B:B:L95	4.84	4	2	8
105	B:B:W99	6.90857	7	1	9
106	B:B:Y105	4.02333	6	2	6
107	B:B:Y111	4.95	4	0	4
108	B:B:C114	3.4175	4	2	8
109	B:B:I123	3.166	5	16	6
110	B:B:Y124	6.188	5	2	6
111	B:B:L126	3.71	4	2	5
112	B:B:R137	3.2275	4	16	5
113	B:B:H142	6.70167	6	13	9
114	B:B:Y145	4.694	5	1	8
115	B:B:R150	4.0825	4	4	6
116	B:B:F151	4.905	4	16	9
117	B:B:L152	4.6425	4	4	3
118	B:B:I157	4.6375	4	16	7
119	B:B:C166	3.465	4	4	8
120	B:B:L168	4.3225	4	4	6
121	B:B:W169	9.12167	6	13	8
122	B:B:F180	8.12	5	4	7
123	B:B:H183	7.348	5	4	9
124	B:B:V187	5	4	4	9
125	B:B:M188	3.7975	4	1	8
126	B:B:L190	4.1825	4	4	5
127	B:B:L192	3.806	5	4	5
128	B:B:F199	5.12667	6	4	9
129	B:B:V200	5.6025	4	5	6
130	B:B:S201	4.6075	4	4	9
131	B:B:C204	5.91	4	1	7
132	B:B:K209	6.7725	4	4	6
133	B:B:L210	5.14	4	0	5
134	B:B:W211	8.61667	6	4	8
135	B:B:F222	5.726	5	5	8
136	B:B:H225	6.99	7	5	9
137	B:B:I232	6.0325	4	5	8
138	B:B:F234	5.25	4	0	5
139	B:B:F235	5.924	5	14	6
140	B:B:P236	5.3075	4	14	7
141	B:B:F241	5.23571	7	5	6
142	B:B:T243	5.1025	4	5	8
143	B:B:T249	3.5	4	5	6
144	B:B:R251	8.82167	6	5	8
145	B:B:F253	6.23667	6	5	6
146	B:B:D254	3.7975	4	0	9
147	B:B:D258	9.1675	4	5	7
148	B:B:Y264	6.4025	4	0	5
149	B:B:I269	5.2275	4	10	4
150	B:B:I273	4.275	4	10	6
151	B:B:F278	4.442	5	14	7
152	B:B:R283	5.322	5	11	9
153	B:B:Y289	7.324	5	10	7
154	B:B:V296	3.44	4	0	5
155	B:B:W297	10.0225	4	10	8
156	B:B:D298	7.015	4	11	9
157	B:B:L300	3.978	5	11	6
158	B:B:R304	9.44	5	10	5
159	B:B:L308	8.69	4	2	7
160	B:B:H311	6.89	4	0	9
161	B:B:M325	4.432	5	2	5
162	B:B:T329	4.325	4	0	8
163	B:B:W332	9.68167	6	1	9
164	B:B:F335	6.6475	4	0	4
165	B:B:L336	3.53	4	7	7
166	B:B:K337	4.9025	4	2	6
167	B:B:W339	7.18667	6	2	9
168	B:B:N340	5.05	7	2	9
169	W:W:?1	6.02636	11	6	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:L51	B:B:W82	24.7501	6.83	No	Yes	0	9	9
2	B:B:L51	B:B:T87	24.7372	2.95	No	No	0	9	5
3	B:B:R49	B:B:T87	24.7693	2.59	No	No	0	7	5
4	B:B:R49	G:G:F61	24.8017	8.55	No	Yes	0	7	8
5	B:B:N340	G:G:F61	73.074	3.62	Yes	Yes	2	9	8
6	B:B:M45	B:B:N340	100	4.21	Yes	Yes	2	4	9
7	B:B:M45	B:B:W339	83.8317	3.49	Yes	Yes	2	4	9
8	B:B:K337	B:B:W339	82.3085	3.48	Yes	Yes	2	6	9
9	B:B:K337	B:B:T50	82.1773	4.5	Yes	No	0	6	3
10	B:B:R52	B:B:T50	82.0594	7.76	No	No	0	7	3
11	B:B:F335	B:B:R52	81.9413	6.41	Yes	No	0	4	7
12	B:B:L70	B:B:W82	24.9215	3.42	No	Yes	7	5	9
13	B:B:L70	B:B:W63	24.8993	10.25	No	Yes	7	5	7
14	B:B:S84	B:B:W63	49.4377	6.18	No	Yes	0	5	7
15	B:B:S84	G:G:F61	49.4379	7.93	No	Yes	0	5	8
16	A:A:C214	B:B:W99	10.4418	2.61	No	Yes	1	7	9
17	A:A:C214	B:B:Y59	10.5484	6.72	No	Yes	1	7	8
18	B:B:W332	B:B:Y59	54.7115	4.82	Yes	Yes	1	9	8
19	B:B:S316	B:B:W332	81.6641	3.71	No	Yes	0	9	9
20	B:B:C317	B:B:S316	81.7303	3.44	No	No	0	7	9
21	B:B:C317	B:B:G330	81.7964	1.96	No	No	0	7	5
22	B:B:G330	B:B:L336	81.8624	3.42	No	Yes	0	5	7
23	B:B:L336	B:B:W82	56.9263	3.42	Yes	Yes	7	7	9
24	B:B:Q75	B:B:W99	10.4418	4.38	No	Yes	1	9	9
25	B:B:Q75	B:B:Y59	10.5484	24.8	No	Yes	1	9	8
26	A:A:L348	A:A:L353	15.6161	4.15	Yes	Yes	0	9	7
27	A:A:L353	R:R:T346	15.5973	2.95	Yes	Yes	0	7	8
28	R:R:T346	W:W:?1	28.0463	9.87	Yes	Yes	0	8	0
29	R:R:Y402	W:W:?1	76.896	3.92	Yes	Yes	6	6	0
30	R:R:F407	R:R:Y402	77.3565	4.13	Yes	Yes	6	8	6
31	R:R:F407	R:R:L67	79.2059	2.44	Yes	Yes	0	8	8
32	R:R:A410	R:R:L67	79.6844	4.73	No	Yes	0	8	8
33	R:R:A410	R:R:E64	79.8039	4.53	No	No	0	8	7
34	R:R:E64	R:R:K413	80.2809	8.1	No	No	0	7	6
35	B:B:D312	R:R:K413	80.3998	5.53	No	No	0	5	6
36	B:B:D312	B:B:D333	80.5194	7.98	No	No	0	5	9
37	B:B:D333	B:B:F335	80.6383	14.33	No	Yes	0	9	4
38	R:R:R134	W:W:?1	26.5697	6.51	No	Yes	0	9	0
39	R:R:I130	R:R:R134	26.5253	3.76	Yes	No	0	9	9
40	A:A:F215	B:B:W99	18.0393	7.02	Yes	Yes	1	9	9
41	A:A:F215	A:A:L37	17.1642	9.74	Yes	No	1	9	9
42	A:A:H213	B:B:W332	26.5007	5.29	No	Yes	0	8	9
43	A:A:H213	A:A:W258	26.4005	10.58	No	Yes	0	8	5
44	A:A:N256	A:A:W258	26.0874	12.43	Yes	Yes	1	8	5
45	A:A:F259	A:A:N256	17.2755	6.04	Yes	Yes	1	9	8
46	A:A:F259	A:A:I221	16.9915	8.79	Yes	Yes	1	9	8
47	A:A:L37	A:A:L39	16.9425	6.92	No	Yes	1	9	9
48	A:A:F223	A:A:L39	25.0925	2.44	Yes	Yes	1	9	9
49	B:B:M101	B:B:Y59	34.1818	2.39	No	Yes	0	9	8
50	B:B:M101	B:B:Y145	33.9321	2.39	No	Yes	0	9	8
51	A:A:K210	B:B:M188	14.4527	5.76	No	Yes	0	9	8
52	B:B:M188	B:B:Y145	14.6547	3.59	Yes	Yes	1	8	8
53	B:B:C204	B:B:D186	14.8728	4.67	Yes	No	1	7	9
54	B:B:D186	B:B:Y145	14.9733	8.05	No	Yes	1	9	8
55	B:B:C204	B:B:D228	14.1541	12.45	Yes	No	1	7	9
56	A:A:K210	B:B:N230	14.1391	4.2	No	No	0	9	9
57	A:A:F223	A:A:V225	22.7487	2.62	Yes	No	1	9	7
58	A:A:F223	A:A:L266	11.6258	3.65	Yes	No	0	9	9
59	A:A:L268	A:A:V225	12.639	2.98	Yes	No	1	8	7
60	A:A:F307	A:A:I303	12.1429	7.54	Yes	No	0	8	7
61	A:A:I303	A:A:Y287	11.1314	4.84	No	Yes	0	7	7
62	B:B:D83	B:B:L69	21.4476	2.71	Yes	No	2	8	5
63	B:B:I81	B:B:L69	34.994	4.28	Yes	No	2	7	5
64	B:B:I81	B:B:V71	20.1793	4.61	Yes	Yes	2	7	8
65	B:B:V71	B:B:Y105	14.2383	5.05	Yes	Yes	2	8	6
66	B:B:H62	B:B:Y105	27.4601	4.36	No	Yes	0	6	6
67	B:B:H62	B:B:R150	27.1651	4.51	No	Yes	0	6	6
68	B:B:L190	B:B:R150	12.2438	2.43	Yes	Yes	4	5	6
69	B:B:I81	B:B:L126	14.3919	4.28	Yes	Yes	2	7	5
70	B:B:L126	B:B:Y105	14.106	3.52	Yes	Yes	2	5	6
71	B:B:L192	B:B:R150	14.0356	2.43	Yes	Yes	4	5	6
72	B:B:D228	B:B:D246	14.0625	2.66	No	No	0	9	9
73	B:B:D246	B:B:S227	27.8918	7.36	No	No	0	9	6
74	B:B:D247	B:B:S227	27.6838	5.89	No	No	0	9	6
75	B:B:D247	B:B:T249	27.2675	2.89	No	Yes	0	9	6
76	B:B:H225	B:B:T249	17.6875	2.74	Yes	Yes	5	9	6
77	B:B:D246	B:B:N230	14.0377	8.08	No	No	0	9	9
78	B:B:I43	B:B:M45	19.5022	4.37	No	Yes	0	3	4
79	B:B:I43	B:B:V40	19.3497	3.07	No	Yes	0	3	3
80	B:B:D298	B:B:V40	16.9818	8.76	Yes	Yes	11	9	3
81	B:B:D298	B:B:L300	16.4184	5.43	Yes	Yes	11	9	6
82	B:B:A299	B:B:L300	10.9124	1.58	No	Yes	0	5	6
83	B:B:A299	B:B:L285	10.7567	1.58	No	No	0	5	6
84	B:B:D83	B:B:Y85	14.1007	5.75	Yes	No	2	8	4
85	B:B:Y85	G:G:P60	27.8916	4.17	No	No	2	4	9
86	R:R:I130	R:R:L78	18.8497	2.85	Yes	Yes	0	9	9
87	R:R:I349	W:W:?1	10.6815	3.82	No	Yes	6	7	0
88	R:R:I349	R:R:I399	10.5472	2.94	No	Yes	0	7	8
89	R:R:F403	W:W:?1	10.6815	13.05	No	Yes	6	8	0
90	R:R:F403	R:R:I399	10.5472	7.54	No	Yes	0	8	8
91	R:R:L127	R:R:Y400	22.2839	5.86	Yes	Yes	0	8	9
92	R:R:I350	R:R:T346	12.2995	3.04	No	Yes	0	8	8
93	R:R:I399	R:R:Y400	11.4143	3.63	Yes	Yes	0	8	9
94	R:R:F354	R:R:L127	26.47	2.44	Yes	Yes	0	9	8
95	R:R:F204	R:R:F354	26.9133	6.43	Yes	Yes	0	8	9
96	R:R:F204	R:R:L359	20.8111	8.53	Yes	Yes	0	8	7
97	R:R:L359	R:R:P360	15.6009	3.28	Yes	No	0	7	9
98	R:R:I385	R:R:P360	14.7348	1.69	Yes	No	0	6	9
99	B:B:M61	B:B:S72	24.6795	4.6	No	Yes	7	6	9
100	B:B:N340	G:G:N59	13.7395	6.81	Yes	Yes	2	9	9
101	G:G:N59	G:G:P60	14.0618	6.52	Yes	No	2	9	9
102	B:B:M325	B:B:N340	13.8247	2.8	Yes	Yes	2	5	9
103	B:B:M325	G:G:P60	14.0616	10.06	Yes	No	2	5	9
104	B:B:M61	B:B:W63	24.7026	5.82	No	Yes	7	6	7
105	B:B:L336	B:B:S72	24.6006	3	Yes	Yes	7	7	9
106	B:B:R68	B:B:Y85	13.7836	8.23	Yes	No	2	5	4
107	B:B:L69	B:B:R68	13.6858	2.43	No	Yes	2	5	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
A:A:C351	A:A:L353	6.35	0	No	Yes	4	7	2	2
A:A:C351	R:R:R134	6.96	0	No	No	4	9	2	1
A:A:G352	W:W:?1	3.43	0	No	Yes	8	0	1	0
A:A:L353	R:R:T346	2.95	0	Yes	Yes	7	8	2	1
R:R:G53	R:R:Y402	2.9	6	No	Yes	9	6	1	1
R:R:G53	W:W:?1	3.43	6	No	Yes	9	0	1	0
R:R:C56	R:R:Y402	2.69	6	No	Yes	8	6	2	1
R:R:C56	R:R:F411	2.79	6	No	Yes	8	8	2	2
R:R:V57	R:R:Y402	5.05	6	Yes	Yes	9	6	2	1
R:R:F407	R:R:V57	6.55	6	Yes	Yes	8	9	2	2
R:R:I130	R:R:R134	3.76	0	Yes	No	9	9	2	1
R:R:R134	W:W:?1	6.51	0	No	Yes	9	0	1	0
R:R:I349	R:R:K345	4.36	6	No	No	7	7	1	1
R:R:K345	W:W:?1	7.55	6	No	Yes	7	0	1	0
R:R:I350	R:R:T346	3.04	0	No	Yes	8	8	2	1
R:R:T346	W:W:?1	9.87	0	Yes	Yes	8	0	1	0
R:R:I349	R:R:I399	2.94	6	No	Yes	7	8	1	2
R:R:I349	W:W:?1	3.82	6	No	Yes	7	0	1	0
R:R:F403	R:R:V398	2.62	6	No	No	8	6	1	1
R:R:V398	W:W:?1	5.98	6	No	Yes	6	0	1	0
R:R:F403	R:R:I399	7.54	6	No	Yes	8	8	1	2
R:R:F407	R:R:Y402	4.13	6	Yes	Yes	8	6	2	1
R:R:F411	R:R:Y402	11.35	6	Yes	Yes	8	6	2	1
R:R:Y402	W:W:?1	3.92	6	Yes	Yes	6	0	1	0
R:R:F403	W:W:?1	13.05	6	No	Yes	8	0	1	0
R:R:K405	R:R:Q408	5.42	0	No	No	6	9	1	2
R:R:K405	W:W:?1	6.61	0	No	Yes	6	0	1	0
R:R:F407	R:R:F411	8.57	6	Yes	Yes	8	8	2	2
R:R:C49	W:W:?1	2.12	0	No	Yes	5	0	1	0
R:R:G53	R:R:L52	1.71	6	No	No	9	4	1	2
R:R:K342	R:R:T346	1.5	0	No	Yes	8	8	2	1
R:R:K405	R:R:N409	1.4	0	No	No	6	6	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
83.33	Single	9KVG	PtdIns4P	9KVG-5-HT_1A-5-MeO-DMT-PtdIns4P-Gi1/β1/γ2
75.00	Single	9KVH	PtdIns4P	9KVH-5-HT_1A-Cinobufotenine-PtdIns4P-Gi1/β1/γ2
69.23	Single	7E2Z	PtdIns4P	7E2Z-5-HT_1A-Aripiprazole-PtdIns4P-Gi1/β1/γ2
69.23	Single	8FYE	PtdIns4P	8FYE-5-HT_1A-4-F,5-MeO-PyrT-PtdIns4P-Gi1/β1/γ1
66.67	Single	9DYE	PtdIns4P	9DYE-5-HT_1A-Buspirone-PtdIns4P-Go/β1/γ2
66.67	Single	9DYF	PtdIns4P	9DYF-5-HT_1A-Asenapine-PtdIns4P-Gi1/β1/γ2
64.29	Single	8FY8	PtdIns4P	8FY8-5-HT_1A-5-MeO-DMT-PtdIns4P-Gi1/β1/γ1
64.29	Single	8FYL	PtdIns4P	8FYL-5-HT_1A-Vilazodone-PtdIns4P-Gi1/β1/γ1
58.33	Single	9DYD	PtdIns4P	9DYD-5-HT_1A-Asenapine-PtdIns4P-Go/β1/γ2
57.14	Single	7E2Y	PtdIns4P	7E2Y-5-HT_1A-Serotonin-PtdIns4P-Gi1/β1/γ2
57.14	Single	8FYT	PtdIns4P	8FYT-5-HT_1A-LSD-PtdIns4P-Gi1/β1/γ1
53.85	Single	9MD1	PtdIns4P	9MD1-5-HT_1A-Buspirone-PtdIns4P-Gz/β1/γ2
53.33	Single	8FYX	PtdIns4P	8FYX-5-HT_1A-Buspirone-PtdIns4P-Gi1/β1/γ1
50.00	Single	8JT6	PtdIns4P	8JT6-5-HT_1A-(R)-IHCH-7179-PtdIns4P-Gi1/β1/γ2
36.36	Single	9KVI	PtdIns4P	9KVI-5-HT_1A-Bufotenin-PtdIns4P-Gi1/β1/γ2
31.58	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
28.57	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
26.67	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
26.67	Single	6KK7	PF-06372222	6KK7-GLP-1-PF-06372222
25.00	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
25.00	Single	6KJV	PF-06372222	6KJV-GLP-1-PF-06372222
25.00	Single	6KK1	PF-06372222	6KK1-GLP-1-PF-06372222
23.81	Single	6LN2	PF-06372222	6LN2-GLP-1-PF-06372222
23.53	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
23.08	Single	9L84	Atazanavir	9L84-β₁-Epinephrine-Atazanavir-Gs/β1/γ2
22.22	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
21.43	Single	7EB2	rac-BHFF	7EB2-GABAB2; GABAB1-Baclofen-rac-BHFF-Gi1/β1/γ2
18.75	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
17.65	Single	7C7Q	BHFF	7C7Q-GABA_B1, GABA_B2-Baclofen-BHFF
16.67	Single	8XQS	Flufenamic acid	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
15.79	Single	8JPF	SBI-553	8JPF-NTS₁-Neurotensin-(8-13)-SBI-553
13.33	Single	9L80	Atazanavir	9L80-GPR119-Atazanavir-chim(NtGi1-Gs)/β1/γ2
12.00	Single	8FN0	SBI-553	8FN0-NTS₁-Neurotensin-(8-13)-SBI-553-chim(NtGi1-Go)/β1/γ2
11.11	Single	8XQR	Flufenamic acid	8XQR-TAS2R14-Flufenamic acid-Gt3/β1/γ1
11.11	Single	9L8L	Atazanavir	9L8L-β₂-BI167107-Atazanavir-Gs/β1/γ2 ; Arrestin2
10.53	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
10.53	Single	8XQO	Aristolochic acid A	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
10.00	Single	8JPC	SBI-553; GDP; Mg	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
10.00	Single	8XQL	Aristolochic acid A	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
9.52	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
9.52	Single	8GW8	PCO371	8GW8-PTH1-PCO371-Gs/β1/γ2
9.09	Single	8JPB	SBI-553; GDP; Mg	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
8.70	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
8.70	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/β1/γ2
8.70	Single	8ZYU	SBI-553	8ZYU-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
8.70	Single	8ZYY	SBI-553	8ZYY-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
7.69	Single	8ZYT	SBI-553	8ZYT-NTS₁-Neurotensin-(8-13)-SBI-553-Arrestin2
7.14	Single	6UO8	GS39783	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
7.14	Single	7DUQ	PubChem 156022738	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
6.45	Single	3VG9	Antibody	3VG9-A_2A-ZM-241385-Antibody
5.88	Single	3VGA	Antibody	3VGA-A_2A-ZM-241385-Antibody
5.88	Single	8XQP	Aristolochic acid A	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
5.56	Single	5T1A	PubChem 12093170	5T1A-CCR2-BMS-681-PubChem 12093170
5.26	Single	8XQN	Aristolochic acid A	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
5.00	Single	5X7D	PubChem 129318963	5X7D-β₂-Carazolol-PubChem 129318963
4.76	Single	6QZH	PubChem 136165388; Na	6QZH-CCR7-PubChem 136165388; Na
4.35	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
4.35	Single	9PEE	PF-07054894; OXM2	9PEE-CCR6-PF-07054894; OXM2
2.78	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
2.70	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
2.70	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
2.63	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
2.63	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
2.56	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
2.50	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2

PDB Summary
PDB	7E2X
Class	A
SubFamily	Amine
Type	5-Hydroxytryptamine
SubType	5-HT1A
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	PtdIns4P
Protein Partners	Gi1/Beta1/Gamma2
PDB Resolution	3
Date	2021-04-14
D.O.I.	doi.org/10.1038/s41586-021-03376-8

Net Summary
I_min	2.43
Number of Linked Nodes	790
Number of Links	980
Number of Hubs	169
Number of Links mediated by Hubs	613
Number of Communities	29
Number of Nodes involved in Communities	245
Number of Links involved in Communities	351

Path Summary
Number Of Nodes in MetaPath	108
Number Of Links MetaPath	107
Number of Shortest Paths	3274271
Length Of Smallest Path	3
Average Path Length	37.3478
Length of Longest Path	65
Minimum Path Strength	1.29
Average Path Strength	5.24499
Maximum Path Strength	22.425
Minimum Path Correlation	0.7
Average Path Correlation	0.98529
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.12766
Average % Of Corr. Nodes	32.5731
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	54.7788
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• cation binding • binding • ion binding • serotonin binding • amine binding • heterocyclic compound binding • small molecule binding • G protein-coupled amine receptor activity • G protein-coupled serotonin receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • Gi/o-coupled serotonin receptor activity • neurotransmitter receptor activity • serotonin receptor activity • protein binding • signaling receptor binding • receptor-receptor interaction • tetrapyrrole binding • heme binding • electron transfer activity • transition metal ion binding • iron ion binding • metal ion binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • behavior • multicellular organismal process • exploration behavior • regulation of amine metabolic process • dopamine metabolic process • primary metabolic process • catechol-containing compound metabolic process • regulation of primary metabolic process • amine metabolic process • catecholamine metabolic process • phenol-containing compound metabolic process • metabolic process • regulation of catecholamine metabolic process • regulation of metabolic process • biogenic amine metabolic process • regulation of dopamine metabolic process • adult behavior • regulation of tube diameter • system process • regulation of tube size • regulation of system process • circulatory system process • regulation of blood circulation • regulation of vasoconstriction • vascular process in circulatory system • regulation of multicellular organismal process • blood vessel diameter maintenance • regulation of biological quality • blood circulation • vasoconstriction • regulation of anatomical structure size • cell-cell signaling • gamma-aminobutyric acid signaling pathway • regulation of behavior • serotonin metabolic process • indole-containing compound metabolic process • cellular response to nitrogen compound • response to dopamine • serotonin receptor signaling pathway • cellular response to dopamine • response to monoamine • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • response to catecholamine • cellular response to monoamine stimulus • response to chemical • cellular response to catecholamine stimulus • cell population proliferation • positive regulation of cell population proliferation • regulation of cell population proliferation • positive regulation of biological process • positive regulation of cellular process • regulation of localization • regulation of hormone secretion • transport • hormone secretion • localization • regulation of secretion by cell • secretion by cell • signal release • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • export from cell • establishment of localization • regulation of secretion • regulation of cell communication • hormone transport • monoamine transport • nitrogen compound transport • organic hydroxy compound transport • monoatomic ion transport • serotonin secretion • regulation of monoatomic ion transport • regulation of serotonin secretion • serotonin transport • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • chemical synaptic transmission • behavioral defense response • fear response • behavioral fear response • defense response • response to stress • multicellular organismal response to stress • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • electron transport chain • generation of precursor metabolites and energy • cell periphery • cellular anatomical structure • plasma membrane • membrane • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • synapse • cell junction • periplasmic space • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • adenylate cyclase-activating dopamine receptor signaling pathway • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • enzyme regulator activity • adenylate cyclase inhibitor activity • cyclase regulator activity • molecular function inhibitor activity • cyclase inhibitor activity • molecular function regulator activity • enzyme inhibitor activity • adenylate cyclase regulator activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • neuropeptide signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • regulation of biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • cell surface receptor signaling pathway • response to cytokine • response to chemokine • cytokine-mediated signaling pathway • cellular response to chemokine • chemokine-mediated signaling pathway • response to peptide • cellular response to cytokine stimulus • relaxation of smooth muscle • regulation of muscle system process • muscle system process • relaxation of muscle • positive regulation of relaxation of smooth muscle • positive regulation of relaxation of muscle • positive regulation of multicellular organismal process • regulation of relaxation of smooth muscle • regulation of relaxation of muscle • negative regulation of protein transport • establishment of protein localization • negative regulation of biological process • negative regulation of transport • negative regulation of secretion • negative regulation of hormone secretion • negative regulation of secretion by cell • intracellular protein localization • regulation of peptide hormone secretion • negative regulation of peptide hormone secretion • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • regulation of protein secretion • negative regulation of protein secretion • regulation of protein localization • regulation of peptide secretion • negative regulation of signaling • negative regulation of cell communication • protein localization to extracellular region • negative regulation of peptide secretion • peptide secretion • negative regulation of cellular process • negative regulation of protein localization • regulation of peptide transport • regulation of establishment of protein localization • regulation of protein transport • peptide transport • negative regulation of insulin secretion • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • insulin secretion • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • sperm principal piece • 9+2 motile cilium • sperm flagellum • motile cilium • nucleoplasm • Golgi apparatus • endomembrane system • ciliary basal body
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Ras-like P-loop GTPases
SCOP2	Family Identifier	• Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	J40
PDB Residues	W:W:?1
Environment Details	Open EMBL-EBI Page
Code	J40
Name	[(2R)-1-[oxidanyl-[(2R,3R,5S,6R)-2,3,5,6-tetrakis(oxidanyl)-4-phosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-3-tetradecanoyloxy-propan-2-yl] (5E,8E)-hexadeca-5,8,11,14-tetraenoate
Synonyms
Identifier
Formula	C39 H68 O16 P2
Molecular Weight	854.895
SMILES
PubChem
Formal Charge	0
Total Atoms	125
Total Chiral Atoms	5
Total Bonds	125
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63096
Sequence	>7E2X_Chain_A T L S A E D K A A V E R S K M I D R N L R E D G E K A A R E V K L L L L G A G E S G K N T I V K Q M K I T G I V E T H F T F K D L H F K M F D V G A Q R S E R K K W I H C F E G V T A I I F C V A L S D Y D L V L N R M H A S M K L F D S I C N N K W F T D T S I I L F L N K K D L F E E K I K K S P L T I C Y P E Y A G S N T Y E E A A A Y I Q C Q F E D L N K R K D T K E I Y T H F T C S T D T K N V Q F V F D A V T D V I I K N N L K D C G L F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>7E2X_Chain_G Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P08908
Sequence	>7E2X_Chain_R Y Q V I T S L L L G T L I F C A V L G N A C V V A A I A L E R S L Q N V A N Y L I G S L A V T D L M V S V L V L P M A A L Y Q V L N K W T L G Q V T C D L F I A L D V L C C T S S I W H L C A I A L D R Y W A I T D P I D Y V N K R T P R R A A A L I S L T W L I G F L I S I P P M L G W P D A C T I S K D H G Y T I Y S T F G A F Y I P L L L M L V L Y G R I F R A A R F R I R K K N E R N A E A K R K M A L A R E R K T V K T L G I I M G T F I L C W L P F F I V A L V L P F C E S S C H M P T L L G A I I N W L G Y S N S L L N P V I Y A Y F N K D F Q N A F K K I I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>7E2X_Chain_B Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7E2X (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	-	PtdIns4P		3	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Y	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Serotonin	PtdIns4P	Gi1/β1/γ2	3	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Y (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Serotonin	PtdIns4P		3	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Z	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Aripiprazole	PtdIns4P	Gi1/β1/γ2	3.1	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Z (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Aripiprazole	PtdIns4P		3.1	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	8JSP	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Ulotaront	-	Gi1/β1/γ2	3.65	2023-11-15	doi.org/10.1038/s41586-023-06804-z
	8JSP (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Ulotaront	-		3.65	2023-11-15	doi.org/10.1038/s41586-023-06804-z
	8W8B	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	SEP-363856	-	Gi1/β1/γ2	3	2023-11-22	doi.org/10.1038/s41586-023-06775-1
	8W8B (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	SEP-363856	-		3	2023-11-22	doi.org/10.1038/s41586-023-06775-1
	8FY8	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P	Gi1/β1/γ1	2.79	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FY8 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P		2.79	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYE	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	4-F,5-MeO-PyrT	PtdIns4P	Gi1/β1/γ1	2.85	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYE (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	4-F,5-MeO-PyrT	PtdIns4P		2.85	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYL	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Vilazodone	PtdIns4P	Gi1/β1/γ1	2.94	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYL (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Vilazodone	PtdIns4P		2.94	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYT	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	LSD	PtdIns4P	Gi1/β1/γ1	2.64	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYT (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	LSD	PtdIns4P		2.64	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYX	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P	Gi1/β1/γ1	2.72	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYX (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P		2.72	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8PJK	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	ST171	-	Gi1/β1/γ1	2.4	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8PJK (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	ST171	-		2.4	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8PKM	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-	Gi1/β1/γ1	2.9	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8PKM (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-		2.9	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8JT6	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	(R)-IHCH-7179	PtdIns4P	Gi1/β1/γ2	3	2024-02-28	doi.org/10.1016/j.cell.2024.02.034
	8JT6 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	(R)-IHCH-7179	PtdIns4P		3	2024-02-28	doi.org/10.1016/j.cell.2024.02.034
	9GL2	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-	Gs/β1/γ2	3.2	2025-07-02	doi.org/10.1126/sciadv.adv9267
	9GL2 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-		3.2	2025-07-02	doi.org/10.1126/sciadv.adv9267
	9DYD	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P	Go/β1/γ2	2.96	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYD (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P		2.96	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYE	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P	Go/β1/γ2	2.9	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYE (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P		2.9	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYF	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P	Gi1/β1/γ2	2.74	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYF (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P		2.74	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9MD1	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P	Gz/β1/γ2	3.03	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9MD1 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P		3.03	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9VJ5	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Gepirone	-	Go/β1/γ2	2.69	2025-11-12	To be published
	9VJ5 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Gepirone	-		2.69	2025-11-12	To be published
	9VJ6	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	F-15599	-	Gi3/β1/γ2	2.62	2025-11-12	To be published
	9VJ6 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	F-15599	-		2.62	2025-11-12	To be published
	9VJE	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-	Go/β1/γ2	2.47	2025-11-12	To be published
	9VJE (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-		2.47	2025-11-12	To be published
	9VJF	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-	Gi3/β1/γ2	2.7	2025-11-12	To be published
	9VJF (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-		2.7	2025-11-12	To be published
	9VJG	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	8-OH-DPAT	-	chim(NtGi2-Gz)/β1/γ2	2.67	2025-11-12	To be published
	9VJG (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	8-OH-DPAT	-		2.67	2025-11-12	To be published
	9VMY	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	TMU4142	-	Go/β1/γ2	2.86	2025-11-12	To be published
	9VMY (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	TMU4142	-		2.86	2025-11-12	To be published
	9VNF	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Pindolol	-	Go/β1/γ2	2.74	2025-11-12	To be published
	9VNF (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Pindolol	-		2.74	2025-11-12	To be published
	9KVG	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P	Gi1/β1/γ2	2.63	2025-12-03	To be published
	9KVG (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P		2.63	2025-12-03	To be published
	9KVH	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Cinobufotenine	PtdIns4P	Gi1/β1/γ2	2.59	2025-12-03	To be published
	9KVH (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Cinobufotenine	PtdIns4P		2.59	2025-12-03	To be published
	9KVI	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Bufotenin	PtdIns4P	Gi1/β1/γ2	2.54	2025-12-03	To be published
	9KVI (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Bufotenin	PtdIns4P		2.54	2025-12-03	To be published
	9HYI	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	DP81	-	Gi1/β1/γ2	2.3	2026-01-21	To be published
	9HYI (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	DP81	-		2.3	2026-01-21	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7E2X.zip

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