Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:L43 4.545427
2R:R:N54 5.3675419
3R:R:V57 3.87619
4R:R:L67 3.124508
5R:R:L74 4.2525408
6R:R:L78 3.61519
7R:R:D82 3.98519
8R:R:S86 3.1575408
9R:R:L90 3.318508
10R:R:V98 1.536526
11R:R:W102 5.61833649
12R:R:F112 5.415406
13R:R:T121 3.388508
14R:R:W125 5.04467
15R:R:H126 7.20286718
16R:R:I130 4.2325409
17R:R:Y135 8.592509
18R:R:R148 7.6075408
19R:R:F204 8.57167638
20R:R:Y205 6.5825437
21R:R:P207 4.3275469
22R:R:Y215 5.346579
23R:R:I226 1.44406
24R:R:E340 3.0275408
25R:R:W358 5.80714738
26R:R:L359 5.45407
27R:R:P369 3.7175407
28R:R:M377 3.346554
29R:R:I385 3.3425406
30R:R:W387 5.75528
31R:R:Y390 6.746528
32R:R:N392 7.4125409
33R:R:I399 4.6675408
34R:R:Y400 4.79409
35R:R:Y402 5.224516
36R:R:F407 4.95143718
37R:R:F411 6.7175418
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:W387 R:R:Y390 34.53916.75YesYes288
2R:R:L90 R:R:Y390 39.12914.69YesYes088
3R:R:L90 R:R:S86 37.60923YesYes088
4R:R:N54 R:R:S86 37.7842.98YesYes098
5R:R:N54 R:R:P397 14.94794.89YesNo199
6R:R:P397 R:R:V57 53.91751.77NoYes199
7R:R:V57 R:R:Y402 12.44785.05YesYes196
8R:R:D82 R:R:N54 32.22136.73YesYes199
9R:R:F407 R:R:V57 26.52186.55YesYes189
10R:R:A410 R:R:L67 10.93554.73NoYes088
11R:R:F407 R:R:L67 19.84192.44YesYes088
12R:R:L67 R:R:Q68 10.26671.33YesNo088
13R:R:D82 R:R:L78 69.20742.71YesYes199
14R:R:I130 R:R:L78 52.70922.85YesYes099
15R:R:I130 R:R:L74 64.38184.28YesYes098
16R:R:A153 R:R:L74 21.74943.15NoYes078
17R:R:A153 R:R:Y73 18.931.33NoNo076
18R:R:D133 R:R:L74 43.06565.43NoYes098
19R:R:D133 R:R:R148 36.60619.53NoYes098
20R:R:P150 R:R:Y73 11.18634.17NoNo056
21R:R:H126 R:R:L78 61.6842.57YesYes189
22R:R:L127 R:R:L78 41.50776.92NoYes089
23R:R:D82 R:R:N396 58.85712.69YesNo099
24R:R:L127 R:R:N396 50.0198.24NoNo089
25R:R:D116 R:R:Y390 19.765912.64NoYes088
26R:R:C120 R:R:D116 41.67494.67NoNo078
27R:R:C120 R:R:W358 43.46085.22NoYes078
28R:R:N392 R:R:W358 1007.91YesYes098
29R:R:N392 R:R:N396 92.71988.17YesNo099
30R:R:N386 R:R:Y390 19.1966.98NoYes078
31R:R:F361 R:R:N386 20.08517.25NoNo087
32R:R:F361 R:R:W358 21.9095.01NoYes088
33R:R:A93 R:R:F112 13.20772.77NoYes076
34R:R:F112 R:R:V89 17.55453.93YesNo068
35R:R:D116 R:R:V89 23.28447.3NoNo088
36R:R:L43 R:R:V98 17.82051.49YesYes276
37R:R:F112 R:R:W102 26.54465.01YesYes069
38R:R:H126 R:R:W161 44.42595.29YesNo189
39R:R:L118 R:R:W161 42.30563.42NoNo069
40R:R:F165 R:R:L118 34.66839.74NoNo056
41R:R:F165 R:R:I169 32.09216.28NoNo056
42R:R:I169 R:R:P170 24.27243.39NoNo068
43R:R:P170 R:R:P171 21.63545.84NoNo087
44R:R:I124 R:R:W358 71.23647.05NoYes088
45R:R:I124 R:R:P207 74.05583.39NoYes089
46R:R:P207 R:R:W125 27.56296.76YesYes697
47R:R:T121 R:R:W125 20.25232.43YesYes087
48R:R:F354 R:R:I124 29.63753.77NoNo098
49R:R:F204 R:R:W358 82.91663.01YesYes388
50R:R:F204 R:R:F354 30.42026.43YesNo089
51R:R:C128 R:R:P207 38.73393.77NoYes679
52R:R:L127 R:R:Y400 35.59545.86NoYes089
53R:R:I130 R:R:Y400 44.61596.04YesYes099
54R:R:C128 R:R:L210 37.00134.76NoNo077
55R:R:F354 R:R:M211 42.65528.71NoNo099
56R:R:M211 R:R:Y215 40.48184.79NoYes799
57R:R:L210 R:R:L214 34.21995.54NoNo077
58R:R:L214 R:R:Y135 22.97295.86NoYes079
59R:R:R148 R:R:Y144 26.80295.14YesNo088
60R:R:V145 R:R:Y144 23.50481.26NoNo068
61R:R:N146 R:R:V145 20.19151.48NoNo056
62R:R:I142 R:R:N146 10.12234.25NoNo065
63R:R:P171 R:R:Y195 13.633312.52NoNo078
64R:R:D192 R:R:Y195 10.93553.45NoNo068
65R:R:F204 R:R:L359 68.05238.53YesYes087
66R:R:L359 R:R:P360 49.69223.28YesNo079
67R:R:I385 R:R:P360 47.041.69YesNo069
68R:R:I385 R:R:V364 30.4813.07YesNo066
69R:R:L368 R:R:V364 22.30412.98NoNo546
70R:R:L368 R:R:P369 19.75071.64NoYes047
71R:R:F204 R:R:Y205 14.20325.16YesYes387
72R:R:L347 R:R:Y215 48.59794.69NoYes089
73R:R:I350 R:R:Y400 49.00833.63NoYes089
74R:R:I350 R:R:Y215 46.40938.46NoYes089
75R:R:L347 R:R:T343 42.67041.47NoNo088
76R:R:I226 R:R:T343 36.65931.52YesNo068
77R:R:E340 R:R:I226 21.92421.37YesYes086
78R:R:L395 R:R:N392 12.1974.12NoYes069
79R:R:I363 R:R:L359 14.39327.14NoYes077
80R:R:I385 R:R:L381 11.21677.14YesNo066
81R:R:I363 R:R:V367 11.54341.54NoNo076
82R:R:L43 R:R:W387 23.687210.25YesYes278
83R:R:A93 R:R:Y390 14.89472.67NoYes278
84R:R:D82 R:R:P397 40.73264.83YesNo199
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 7E2X_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 2.57
Number of Linked Nodes 243
Number of Links 279
Number of Hubs 37
Number of Links mediated by Hubs 148
Number of Communities 7
Number of Nodes involved in Communities 51
Number of Links involved in Communities 68
Path Summary
Number Of Nodes in MetaPath 85
Number Of Links MetaPath 84
Number of Shortest Paths 43446
Length Of Smallest Path 3
Average Path Length 11.8883
Length of Longest Path 26
Minimum Path Strength 1.35
Average Path Strength 4.86425
Maximum Path Strength 16.59
Minimum Path Correlation 0.7
Average Path Correlation 0.932583
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 4.7619
Average % Of Corr. Nodes 57.4865
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 47.3249
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• D2 dopamine receptor binding   • protein binding   • binding   • signaling receptor binding   • G protein-coupled receptor binding   • dopamine receptor binding   • phosphorus-oxygen lyase activity   • enzyme regulator activity   • cyclase regulator activity   • molecular function regulator activity   • cyclase activity   • adenylate cyclase regulator activity   • lyase activity   • catalytic activity   • adenylate cyclase activity   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • guanyl ribonucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • cation binding   • magnesium ion binding   • metal ion binding   • GDP binding   • G protein-coupled serotonin receptor binding   • protein-containing complex binding   • G-protein beta/gamma-subunit complex binding   • pyrophosphatase activity   • GTPase activity   • G protein activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • cell communication   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • response to hormone   • response to chemical   • response to endogenous stimulus   • response to peptide hormone   • response to oxygen-containing compound   • response to nitrogen compound   • cell division   • leukocyte migration   • immune system process   • mononuclear cell migration   • lymphocyte migration   • cell migration   • T cell migration   • cell motility   • regulation of steroid biosynthetic process   • regulation of cholesterol biosynthetic process   • regulation of cholesterol metabolic process   • steroid metabolic process   • regulation of lipid metabolic process   • sterol metabolic process   • positive regulation of biological process   • cholesterol metabolic process   • lipid biosynthetic process   • alcohol metabolic process   • regulation of primary metabolic process   • positive regulation of metabolic process   • regulation of small molecule metabolic process   • positive regulation of biosynthetic process   • positive regulation of lipid metabolic process   • small molecule metabolic process   • steroid biosynthetic process   • positive regulation of cellular process   • regulation of biosynthetic process   • secondary alcohol biosynthetic process   • regulation of alcohol biosynthetic process   • small molecule biosynthetic process   • regulation of steroid metabolic process   • cholesterol biosynthetic process   • positive regulation of cholesterol biosynthetic process   • primary metabolic process   • secondary alcohol metabolic process   • positive regulation of steroid biosynthetic process   • biosynthetic process   • sterol biosynthetic process   • positive regulation of lipid biosynthetic process   • regulation of sterol biosynthetic process   • alcohol biosynthetic process   • positive regulation of cholesterol metabolic process   • positive regulation of steroid metabolic process   • metabolic process   • regulation of lipid biosynthetic process   • positive regulation of small molecule metabolic process   • regulation of metabolic process   • positive regulation of alcohol biosynthetic process   • positive regulation of sterol biosynthetic process   • lipid metabolic process   • regulation of cytoskeleton organization   • regulation of cellular component organization   • microtubule cytoskeleton organization   • regulation of mitotic spindle organization   • mitotic cell cycle   • cellular component organization   • cell cycle   • cellular component organization or biogenesis   • regulation of cell cycle   • microtubule cytoskeleton organization involved in mitosis   • spindle organization   • cell cycle process   • regulation of cell cycle process   • regulation of microtubule-based process   • regulation of spindle organization   • regulation of organelle organization   • mitotic spindle organization   • organelle organization   • mitotic cell cycle process   • microtubule-based process   • cytoskeleton organization   • regulation of microtubule cytoskeleton organization   • protein localization   • positive regulation of protein localization to cell periphery   • regulation of localization   • protein localization to cell periphery   • cellular localization   • regulation of protein localization   • positive regulation of protein localization to cell cortex   • regulation of protein localization to cell periphery   • localization   • regulation of cellular localization   • regulation of protein localization to cell cortex   • cellular macromolecule localization   • macromolecule localization   • positive regulation of protein localization   • protein localization to cell cortex   • response to ketone   • response to prostaglandin   • response to lipid   • response to alcohol   • response to prostaglandin E   • cellular response to forskolin   • cellular response to oxygen-containing compound   • cellular response to chemical stimulus   • cellular response to alcohol   • response to forskolin   • cellular response to lipid   • cellular response to ketone   • midbody   • cellular anatomical structure   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle
Gene OntologyCellular Component• midbody   • cellular anatomical structure   • membrane-bounded organelle   • intracellular anatomical structure   • nucleus   • membrane-enclosed lumen   • intracellular membraneless organelle   • intracellular membrane-bounded organelle   • nucleolus   • intracellular organelle lumen   • intracellular organelle   • organelle lumen   • organelle   • membraneless organelle   • nuclear lumen   • cell periphery   • cell cortex   • cytoplasm   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane   • plasma membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • extracellular vesicle   • extracellular organelle   • extracellular region   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • centrosome   • microtubule organizing center   • cytoskeleton   • microtubule cytoskeleton   • centriolar satellite   • cytosol   • nucleoplasm   • vacuolar membrane   • lytic vacuole   • vacuole   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • organelle membrane   • lysosome   • Golgi apparatus   • endomembrane system   • cilium   • plasma membrane bounded cell projection   • ciliary basal body   • cell projection   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • multicellular organismal process   • system process   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • developmental process   • sensory organ development   • eye development   • animal organ development   • retina development in camera-type eye   • visual system development   • multicellular organism development   • camera-type eye development   • anatomical structure development   • sensory system development   • system development   • cell population proliferation   • cellular process   • cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • signal transduction   • cell communication   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • small GTPase-mediated signal transduction   • Ras protein signal transduction   • intracellular signal transduction   • intracellular signaling cassette   • phospholipase C-activating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cellular response to monoamine stimulus   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • non-motile cilium   • 9+0 non-motile cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • photoreceptor cell cilium   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation   • tetrapyrrole binding   • heme binding   • electron transfer activity   • cation binding   • transition metal ion binding   • iron ion binding   • ion binding   • metal ion binding   • small molecule binding   • serotonin binding   • amine binding   • heterocyclic compound binding   • G protein-coupled amine receptor activity   • G protein-coupled serotonin receptor activity   • molecular transducer activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • Gi/o-coupled serotonin receptor activity   • neurotransmitter receptor activity   • serotonin receptor activity   • signaling receptor binding   • receptor-receptor interaction   • electron transport chain   • metabolic process   • generation of precursor metabolites and energy   • adenylate cyclase-inhibiting serotonin receptor signaling pathway   • G protein-coupled serotonin receptor signaling pathway   • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway   • behavior   • exploration behavior   • regulation of amine metabolic process   • dopamine metabolic process   • primary metabolic process   • catechol-containing compound metabolic process   • regulation of primary metabolic process   • amine metabolic process   • catecholamine metabolic process   • phenol-containing compound metabolic process   • regulation of catecholamine metabolic process   • regulation of metabolic process   • biogenic amine metabolic process   • regulation of dopamine metabolic process   • regulation of tube diameter   • regulation of tube size   • regulation of system process   • circulatory system process   • regulation of blood circulation   • regulation of vasoconstriction   • vascular process in circulatory system   • regulation of multicellular organismal process   • blood vessel diameter maintenance   • regulation of biological quality   • blood circulation   • vasoconstriction   • regulation of anatomical structure size   • gamma-aminobutyric acid signaling pathway   • regulation of behavior   • ammonium ion metabolic process   • serotonin metabolic process   • indole-containing compound metabolic process   • primary amino compound metabolic process   • serotonin receptor signaling pathway   • positive regulation of cell population proliferation   • regulation of cell population proliferation   • positive regulation of biological process   • positive regulation of cellular process   • regulation of localization   • regulation of hormone secretion   • transport   • hormone secretion   • localization   • regulation of secretion by cell   • secretion by cell   • signal release   • regulation of signaling   • regulation of transport   • secretion   • regulation of hormone levels   • export from cell   • establishment of localization   • regulation of secretion   • regulation of cell communication   • hormone transport   • monoamine transport   • nitrogen compound transport   • organic hydroxy compound transport   • monoatomic ion transport   • serotonin secretion   • regulation of monoatomic ion transport   • regulation of serotonin secretion   • serotonin transport   • trans-synaptic signaling   • anterograde trans-synaptic signaling   • chemical synaptic transmission   • behavioral defense response   • fear response   • behavioral fear response   • defense response   • response to stress   • multicellular organismal response to stress   • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger   • periplasmic space   • somatodendritic compartment   • dendrite   • dendritic tree
SCOP2Domain Identifier• Ras-like P-loop GTPases
SCOP2Family Identifier• Ras-like P-loop GTPases
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP08908
Sequence
>7E2X_nogp_Chain_R
YQVITSLLL GTLIFCAVL GNACVVAAI ALERSLQNV ANYLIGSLA 
VTDLMVSVL VLPMAALYQ VLNKWTLGQ VTCDLFIAL DVLCCTSSI 
WHLCAIALD RYWAITDPI DYVNKRTPR RAAALISLT WLIGFLISI 
PPMLGWPDA CTISKDHGY TIYSTFGAF YIPLLLMLV LYGRIFRAA 
RFRIRKKNE RNAEAKRKM ALARERKTV KTLGIIMGT FILCWLPFF 
IVALVLPFC ESSCHMPTL LGAIINWLG YSNSLLNPV IYAYFNKDF 
QNAFKKII


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8PKMAAmine5-Hydroxytryptamine5-HT1AHomo sapiensBefiradolt7mGi1/β1/γ12.92024-05-29To be published
8PKM (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensBefiradolt7m2.92024-05-29To be published
8PJKAAmine5-Hydroxytryptamine5-HT1AHomo sapiensST171t7mGi1/β1/γ12.42024-05-29To be published
8PJK (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensST171t7m2.42024-05-29To be published
8FYXAAmine5-Hydroxytryptamine5-HT1AHomo sapiensBuspirone-Gi1/β1/γ12.722024-05-1510.1038/s41586-024-07403-2
8FYX (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensBuspirone-2.722024-05-1510.1038/s41586-024-07403-2
8FYTAAmine5-Hydroxytryptamine5-HT1AHomo sapiensLSD-Gi1/β1/γ12.642024-05-1510.1038/s41586-024-07403-2
8FYT (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensLSD-2.642024-05-1510.1038/s41586-024-07403-2
8FYLAAmine5-Hydroxytryptamine5-HT1AHomo sapiensVilazodone-Gi1/β1/γ12.942024-05-1510.1038/s41586-024-07403-2
8FYL (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensVilazodone-2.942024-05-1510.1038/s41586-024-07403-2
8FYEAAmine5-Hydroxytryptamine5-HT1AHomo sapiens4-F,5-MeO-PyrT-Gi1/β1/γ12.852024-05-1510.1038/s41586-024-07403-2
8FYE (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiens4-F,5-MeO-PyrT-2.852024-05-1510.1038/s41586-024-07403-2
8FY8AAmine5-Hydroxytryptamine5-HT1AHomo sapiens5-MeO-DMT-Gi1/β1/γ12.792024-05-1510.1038/s41586-024-07403-2
8FY8 (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiens5-MeO-DMT-2.792024-05-1510.1038/s41586-024-07403-2
8JT6AAmine5-Hydroxytryptamine5-HT1AHomo sapiens(R)-IHCH-7179-Gi1/β1/γ232024-02-28To be published
8JT6 (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiens(R)-IHCH-7179-32024-02-28To be published
8W8BAAmine5-Hydroxytryptamine5-HT1AHomo sapiensSEP-363856-Gi1/β1/γ232023-11-2210.1038/s41586-023-06775-1
8W8B (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensSEP-363856-32023-11-2210.1038/s41586-023-06775-1
8JSPAAmine5-Hydroxytryptamine5-HT1AHomo sapiensUlotaront-Gi1/β1/γ23.652023-11-1510.1038/s41586-023-06804-z
8JSP (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensUlotaront-3.652023-11-1510.1038/s41586-023-06804-z
7E2ZAAmine5-Hydroxytryptamine5-HT1AHomo sapiensAripiprazole-Gi1/β1/γ23.12021-04-1410.1038/s41586-021-03376-8
7E2Z (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensAripiprazole-3.12021-04-1410.1038/s41586-021-03376-8
7E2YAAmine5-Hydroxytryptamine5-HT1AHomo sapiensSerotonin-Gi1/β1/γ232021-04-1410.1038/s41586-021-03376-8
7E2Y (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiensSerotonin-32021-04-1410.1038/s41586-021-03376-8
7E2XAAmine5-Hydroxytryptamine5-HT1AHomo sapiens--Gi1/β1/γ232021-04-1410.1038/s41586-021-03376-8
7E2X (No Gprot) AAmine5-Hydroxytryptamine5-HT1AHomo sapiens--32021-04-1410.1038/s41586-021-03376-8




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7E2X_nogp.zip



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