psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D94	12.77	Yes	No	1	0	8
2	L:L:?1	R:R:Y95	18.76	Yes	Yes	1	0	8
3	L:L:?1	R:R:C98	10.46	Yes	No	0	0	8
4	L:L:?1	R:R:W316	4.29	Yes	Yes	1	0	9
5	L:L:?1	R:R:Y319	8.83	Yes	Yes	1	0	7
6	L:L:?1	R:R:F344	24.07	Yes	Yes	1	0	6
7	L:L:?1	R:R:Q347	17.54	Yes	No	1	0	8
8	L:L:?1	R:R:W348	11.79	Yes	Yes	1	0	8
9	R:R:R15	R:R:T17	3.88	No	No	0	3	3
10	R:R:L18	R:R:R15	13.36	No	No	0	5	3
11	R:R:F21	R:R:T17	3.89	No	No	0	4	3
12	R:R:L18	R:R:L77	4.15	No	No	0	5	6
13	R:R:F20	R:R:F21	5.36	No	No	0	4	4
14	R:R:I73	R:R:M22	4.37	No	No	0	6	7
15	R:R:L77	R:R:M22	7.07	No	No	0	6	7
16	R:R:M22	R:R:W345	13.96	No	Yes	0	7	8
17	R:R:F349	R:R:V25	3.93	No	No	0	4	7
18	R:R:A26	R:R:I69	4.87	No	Yes	0	7	8
19	R:R:D61	R:R:I29	4.2	Yes	No	0	9	8
20	R:R:M30	R:R:V66	4.56	No	No	0	6	5
21	R:R:A58	R:R:N33	4.69	No	No	0	9	9
22	R:R:D61	R:R:N33	17.5	Yes	No	0	9	9
23	R:R:N33	R:R:P355	13.03	No	No	0	9	9
24	R:R:A34	R:R:F62	4.16	No	Yes	0	4	8
25	R:R:P359	R:R:V36	7.07	No	No	0	8	9
26	R:R:F365	R:R:V36	3.93	Yes	No	0	8	9
27	R:R:I37	R:R:L55	4.28	No	No	0	8	7
28	R:R:F62	R:R:I37	3.77	Yes	No	0	8	8
29	R:R:A39	R:R:F369	4.16	No	No	0	8	8
30	R:R:F40	R:R:R47	13.9	Yes	No	2	8	8
31	R:R:F40	R:R:S51	5.28	Yes	No	2	8	9
32	R:R:F40	R:R:Y52	7.22	Yes	Yes	2	8	6
33	R:R:F40	R:R:L55	14.61	Yes	No	0	8	7
34	R:R:I372	R:R:V42	4.61	No	No	0	6	6
35	R:R:D43	R:R:N45	6.73	No	No	0	7	6
36	R:R:D43	R:R:L46	8.14	No	Yes	2	7	9
37	R:R:A368	R:R:D43	4.63	No	No	2	8	7
38	R:R:K44	R:R:R47	4.95	No	No	0	7	8
39	R:R:N45	R:R:R364	15.67	No	No	0	6	7
40	R:R:L46	R:R:S51	4.5	Yes	No	2	9	9
41	R:R:F365	R:R:L46	13.4	Yes	Yes	2	8	9
42	R:R:A368	R:R:L46	4.73	No	Yes	2	8	9
43	R:R:R47	R:R:Y52	6.17	No	Yes	2	8	6
44	R:R:H48	R:R:S50	6.97	No	No	0	7	8
45	R:R:H48	R:R:Y122	8.71	No	Yes	0	7	8
46	R:R:H48	R:R:R364	4.51	No	No	0	7	7
47	R:R:F53	R:R:R49	5.34	Yes	Yes	3	8	7
48	R:R:D111	R:R:R49	10.72	No	Yes	3	9	7
49	R:R:R49	R:R:Y122	5.14	Yes	Yes	3	7	8
50	R:R:Q125	R:R:R49	7.01	No	Yes	0	5	7
51	R:R:R49	R:R:T127	7.76	Yes	No	0	7	8
52	R:R:F365	R:R:S51	5.28	Yes	No	2	8	9
53	R:R:V129	R:R:Y52	5.05	No	Yes	0	4	6
54	R:R:I132	R:R:Y52	9.67	No	Yes	0	7	6
55	R:R:F53	R:R:L107	15.83	Yes	No	0	8	8
56	R:R:D111	R:R:F53	7.17	No	Yes	3	9	8
57	R:R:F53	R:R:I132	3.77	Yes	No	0	8	7
58	R:R:F54	R:R:I108	8.79	Yes	No	0	8	9
59	R:R:F54	R:R:P359	10.11	Yes	No	0	8	8
60	R:R:F54	R:R:H362	5.66	Yes	No	0	8	9
61	R:R:F365	R:R:F54	7.5	Yes	Yes	0	8	8
62	R:R:I59	R:R:L55	7.14	No	No	0	6	7
63	R:R:N104	R:R:N56	12.26	No	Yes	7	8	9
64	R:R:M136	R:R:N56	14.02	No	Yes	0	8	9
65	R:R:N56	R:R:V139	4.43	Yes	No	7	9	8
66	R:R:N56	R:R:W140	10.17	Yes	No	0	9	9
67	R:R:L57	R:R:N354	6.87	No	Yes	0	9	9
68	R:R:F63	R:R:I59	3.77	Yes	No	0	6	6
69	R:R:S101	R:R:S60	4.89	No	No	0	9	9
70	R:R:D61	R:R:S351	11.78	Yes	No	0	9	9
71	R:R:D61	R:R:N354	4.04	Yes	Yes	0	9	9
72	R:R:F62	R:R:F63	5.36	Yes	Yes	0	8	6
73	R:R:F62	R:R:V66	7.87	Yes	No	0	8	5
74	R:R:F63	R:R:I67	7.54	Yes	No	0	6	6
75	R:R:F63	R:R:L97	6.09	Yes	No	0	6	6
76	R:R:V64	R:R:W348	6.13	No	Yes	0	8	8
77	R:R:S351	R:R:V64	6.46	No	No	0	9	8
78	R:R:I67	R:R:T93	4.56	No	No	0	6	5
79	R:R:D94	R:R:S68	8.83	No	No	0	8	8
80	R:R:I69	R:R:W345	4.7	Yes	Yes	1	8	8
81	R:R:I69	R:R:W348	12.92	Yes	Yes	1	8	8
82	R:R:L71	R:R:W90	4.56	No	No	0	5	7
83	R:R:T76	R:R:Y72	21.22	No	Yes	0	5	7
84	R:R:W90	R:R:Y72	8.68	No	Yes	1	7	7
85	R:R:F344	R:R:Y72	8.25	Yes	Yes	1	6	7
86	R:R:W345	R:R:Y72	7.72	Yes	Yes	1	8	7
87	R:R:W348	R:R:Y72	6.75	Yes	Yes	1	8	7
88	R:R:I73	R:R:P74	6.77	No	No	0	6	5
89	R:R:L77	R:R:T76	4.42	No	No	0	6	5
90	R:R:F82	R:R:W80	12.03	Yes	No	0	6	9
91	R:R:F82	R:R:G83	4.52	Yes	No	0	6	7
92	R:R:C87	R:R:F82	8.38	No	Yes	4	9	6
93	R:R:C164	R:R:F82	4.19	No	Yes	4	9	6
94	R:R:C164	R:R:C87	7.28	No	No	4	9	9
95	R:R:E155	R:R:V88	7.13	No	No	0	6	7
96	R:R:F344	R:R:W90	4.01	Yes	No	1	6	7
97	R:R:I151	R:R:L91	7.14	Yes	No	1	7	6
98	R:R:L91	R:R:P166	11.49	No	Yes	1	6	7
99	R:R:D94	R:R:W348	12.28	No	Yes	1	8	8
100	R:R:N147	R:R:Y95	8.14	Yes	Yes	1	8	8
101	R:R:I151	R:R:Y95	4.84	Yes	Yes	1	7	8
102	R:R:P166	R:R:Y95	11.13	Yes	Yes	1	7	8
103	R:R:F169	R:R:Y95	4.13	No	Yes	1	6	8
104	R:R:L96	R:R:W140	6.83	No	No	0	6	9
105	R:R:N147	R:R:T99	5.85	Yes	No	1	8	8
106	R:R:E182	R:R:T99	7.06	No	No	1	8	8
107	R:R:A100	R:R:W140	6.48	No	No	0	8	9
108	R:R:N354	R:R:S101	4.47	Yes	No	0	9	9
109	R:R:F312	R:R:V102	9.18	Yes	No	1	9	8
110	R:R:V102	R:R:W316	9.81	No	Yes	1	8	9
111	R:R:V139	R:R:Y103	3.79	No	No	0	8	7
112	R:R:V146	R:R:Y103	3.79	No	No	0	7	7
113	R:R:N104	R:R:V139	7.39	No	No	7	8	8
114	R:R:I105	R:R:N354	8.5	No	Yes	0	9	9
115	R:R:I105	R:R:Y358	10.88	No	Yes	0	9	9
116	R:R:I108	R:R:R112	5.01	No	No	6	9	9
117	R:R:I108	R:R:Y358	7.25	No	Yes	6	9	9
118	R:R:L114	R:R:Y110	15.24	No	No	0	5	6
119	R:R:F193	R:R:Y110	10.32	Yes	No	0	7	6
120	R:R:D111	R:R:Y122	11.49	No	Yes	3	9	8
121	R:R:R112	R:R:Y358	5.14	No	Yes	6	9	9
122	R:R:S117	R:R:Y113	12.72	No	Yes	0	7	9
123	R:R:Y113	R:R:Y192	3.97	Yes	No	5	9	5
124	R:R:F193	R:R:Y113	8.25	Yes	Yes	5	7	9
125	R:R:N196	R:R:Y113	9.3	No	Yes	5	6	9
126	R:R:S115	R:R:Y122	12.72	No	Yes	0	8	8
127	R:R:N118	R:R:S117	4.47	No	No	0	6	7
128	R:R:I132	R:R:T127	10.64	No	No	0	7	8
129	R:R:K131	R:R:L135	4.23	No	No	0	7	7
130	R:R:F144	R:R:G148	4.52	No	No	0	5	5
131	R:R:F144	R:R:P149	5.78	No	No	0	5	8
132	R:R:N147	R:R:V146	7.39	Yes	No	0	8	7
133	R:R:N147	R:R:T178	4.39	Yes	No	0	8	8
134	R:R:E182	R:R:N147	10.52	No	Yes	1	8	8
135	R:R:I151	R:R:P166	5.08	Yes	Yes	1	7	7
136	R:R:S154	R:R:W157	17.3	Yes	No	0	8	6
137	R:R:S156	R:R:W157	4.94	No	No	0	5	6
138	R:R:K158	R:R:S162	9.18	Yes	No	0	6	3
139	R:R:E163	R:R:E165	7.61	No	No	1	4	4
140	R:R:E163	R:R:P335	4.72	No	No	0	4	4
141	R:R:E163	R:R:K336	13.5	No	Yes	1	4	4
142	R:R:E165	R:R:F169	9.33	No	No	1	4	6
143	R:R:E165	R:R:K336	6.75	No	Yes	1	4	4
144	R:R:F168	R:R:P166	10.11	Yes	Yes	0	6	7
145	R:R:F169	R:R:P166	17.34	No	Yes	1	6	7
146	R:R:F168	R:R:I174	5.02	Yes	No	0	6	8
147	R:R:F168	R:R:T178	5.19	Yes	No	0	6	8
148	R:R:E171	R:R:S170	4.31	No	No	0	6	3
149	R:R:E171	R:R:Y173	12.35	No	No	8	6	4
150	R:R:E171	R:R:I174	5.47	No	No	8	6	8
151	R:R:F328	R:R:W172	20.04	No	No	0	5	4
152	R:R:I174	R:R:Y173	12.09	No	No	8	8	4
153	R:R:L175	R:R:T323	8.84	No	No	0	7	7
154	R:R:I324	R:R:L175	4.28	No	No	0	6	7
155	R:R:I324	R:R:S179	4.64	No	No	0	6	8
156	R:R:F180	R:R:V184	7.87	No	No	0	4	7
157	R:R:F180	R:R:I185	6.28	No	No	0	4	6
158	R:R:E182	R:R:W316	11.99	No	Yes	1	8	9
159	R:R:F183	R:R:V187	7.87	Yes	No	1	9	6
160	R:R:F183	R:R:F312	4.29	Yes	Yes	1	9	9
161	R:R:F183	R:R:W316	4.01	Yes	Yes	1	9	9
162	R:R:A317	R:R:F183	4.16	No	Yes	0	7	9
163	R:R:F312	R:R:V187	5.24	Yes	No	1	9	6
164	R:R:N194	R:R:V190	4.43	No	Yes	0	9	9
165	R:R:F312	R:R:V190	3.93	Yes	Yes	0	9	9
166	R:R:A191	R:R:L309	4.73	No	No	0	5	8
167	R:R:F193	R:R:Y192	5.16	Yes	No	5	7	5
168	R:R:N196	R:R:Y192	17.44	No	No	5	6	5
169	R:R:L305	R:R:N194	8.24	Yes	No	0	8	9
170	R:R:M195	R:R:W199	12.8	No	No	0	3	4
171	R:R:I197	R:R:L305	7.14	No	Yes	0	9	8
172	R:R:L301	R:R:Y198	5.86	No	Yes	0	8	7
173	R:R:L201	R:R:L301	4.15	No	No	0	8	8
174	R:R:D205	R:R:K203	12.44	No	No	0	5	6
175	R:R:E291	R:R:E294	3.81	No	No	0	5	5
176	R:R:R297	R:R:V293	3.92	Yes	No	0	7	5
177	R:R:E294	R:R:R297	5.82	No	Yes	0	5	7
178	R:R:L296	R:R:R299	4.86	No	No	0	4	6
179	R:R:R297	R:R:R300	5.33	Yes	No	0	7	8
180	R:R:L301	R:R:L305	6.92	No	Yes	0	8	8
181	R:R:I307	R:R:K303	4.36	No	No	0	7	7
182	R:R:L308	R:R:L357	5.54	No	No	0	8	8
183	R:R:L308	R:R:Y358	11.72	No	Yes	0	8	9
184	R:R:V311	R:R:V353	4.81	No	No	9	6	7
185	R:R:L357	R:R:V311	4.47	No	No	9	8	6
186	R:R:F312	R:R:W316	6.01	Yes	Yes	1	9	9
187	R:R:C315	R:R:N350	6.3	No	No	0	8	9
188	R:R:Q347	R:R:W316	29.57	No	Yes	1	8	9
189	R:R:N350	R:R:W316	6.78	No	Yes	0	9	9
190	R:R:T323	R:R:Y319	8.74	No	Yes	0	7	7
191	R:R:Y319	R:R:Y340	14.89	Yes	No	0	7	5
192	R:R:A343	R:R:Y319	4	No	Yes	0	5	7
193	R:R:F344	R:R:Y319	8.25	Yes	Yes	1	6	7
194	R:R:Q347	R:R:Y319	9.02	No	Yes	1	8	7
195	R:R:F322	R:R:L326	7.31	No	No	0	6	5
196	R:R:F322	R:R:Y340	7.22	No	No	0	6	5
197	R:R:F328	R:R:Y329	13.41	No	No	0	5	5
198	R:R:K336	R:R:Y340	11.94	Yes	No	0	4	5
199	R:R:K336	R:R:R341	9.9	Yes	No	0	4	6
200	R:R:S337	R:R:W339	4.94	No	No	0	2	5
201	R:R:V338	R:R:W339	6.13	No	No	0	1	5
202	R:R:F344	R:R:W348	7.02	Yes	Yes	1	6	8
203	R:R:W345	R:R:W348	12.18	Yes	Yes	1	8	8
204	R:R:N350	R:R:N354	12.26	No	Yes	0	9	9
205	R:R:L357	R:R:V353	4.47	No	No	9	8	7
206	R:R:H362	R:R:R364	6.77	No	No	0	9	7
207	R:R:K363	R:R:Q366	6.78	No	No	0	5	9
208	R:R:F373	R:R:I372	7.54	No	No	0	7	6
209	R:R:F168	R:R:M150	3.73	Yes	No	0	6	7
210	R:R:V25	R:R:W345	3.68	No	Yes	0	7	8
211	R:R:F27	R:R:L31	3.65	No	No	0	5	4
212	R:R:F373	R:R:L35	3.65	No	No	0	7	8
213	R:R:F193	R:R:L189	3.65	Yes	No	0	7	7
214	R:R:F352	R:R:L356	3.65	No	No	0	6	6
215	R:R:L201	R:R:R297	3.64	No	Yes	0	8	7
216	R:R:L295	R:R:R299	3.64	No	No	0	4	6
217	R:R:P186	R:R:V102	3.53	No	No	0	9	8
218	R:R:P186	R:R:V106	3.53	No	No	0	9	7
219	R:R:K203	R:R:W202	3.48	No	No	0	6	6
220	R:R:I69	R:R:P70	3.39	Yes	No	0	8	9
221	R:R:I185	R:R:P186	3.39	No	No	0	6	9
222	R:R:N196	R:R:W199	3.39	No	No	0	6	4
223	R:R:L346	R:R:P318	3.28	No	No	0	8	9
224	R:R:S179	R:R:S320	3.26	No	No	0	8	8
225	R:R:C87	R:R:K158	3.23	No	Yes	4	9	6
226	R:R:S109	R:R:V190	3.23	No	Yes	0	9	9
227	R:R:S200	R:R:V116	3.23	No	No	0	6	8
228	R:R:S154	R:R:V153	3.23	Yes	No	0	8	5
229	R:R:C164	R:R:K158	3.23	No	Yes	4	9	6
230	R:R:F365	R:R:F369	3.22	Yes	No	0	8	8
231	R:R:T14	R:R:V16	3.17	No	No	0	5	5
232	R:R:A317	R:R:L321	3.15	No	No	0	7	6
233	R:R:I197	R:R:V116	3.07	No	No	0	9	8
234	R:R:I188	R:R:V184	3.07	No	No	0	4	7
235	R:R:I342	R:R:V338	3.07	No	No	0	5	1
236	R:R:I151	R:R:T92	3.04	Yes	No	0	7	6
237	R:R:K131	R:R:T127	3	No	No	0	7	8
238	R:R:L175	R:R:S327	3	No	No	0	7	6
239	R:R:L38	R:R:V42	2.98	No	No	0	4	6
240	R:R:L189	R:R:V106	2.98	No	No	0	7	7
241	R:R:L145	R:R:V141	2.98	No	No	0	4	4
242	R:R:L181	R:R:V146	2.98	No	No	0	5	7
243	R:R:L309	R:R:V190	2.98	No	Yes	0	8	9
244	R:R:W202	R:R:Y198	2.89	No	Yes	0	6	7
245	R:R:A28	R:R:F352	2.77	No	No	0	4	6
246	R:R:L31	R:R:L35	2.77	No	No	0	4	8
247	R:R:A313	R:R:F183	2.77	No	Yes	0	6	9
248	R:R:A298	R:R:Y198	2.67	No	Yes	0	8	7
249	R:R:A302	R:R:Y198	2.67	No	Yes	0	7	7
250	R:R:E155	R:R:L152	2.65	No	No	0	6	5
251	R:R:E291	R:R:L295	2.65	No	No	0	5	4
252	R:R:F168	R:R:S154	2.64	Yes	Yes	0	6	8
253	R:R:F322	R:R:S337	2.64	No	No	0	6	2
254	R:R:F78	R:R:V16	2.62	No	No	0	5	5
255	R:R:F144	R:R:T92	2.59	No	No	0	5	6
256	R:R:D81	R:R:H75	2.52	No	No	0	3	6
257	R:R:F352	R:R:I29	2.51	No	No	0	6	8
258	R:R:F89	R:R:I67	2.51	No	No	0	4	6
259	R:R:F27	R:R:M30	2.49	No	No	0	5	6
260	R:R:S327	R:R:W172	2.47	No	No	0	6	4
261	R:R:F20	R:R:L24	2.44	No	No	0	4	5
262	R:R:F349	R:R:L346	2.44	No	No	0	4	8
263	R:R:F369	R:R:L360	2.44	No	No	0	8	6
264	R:R:L142	R:R:Y103	2.34	No	No	0	5	7
265	R:R:F82	R:R:H75	2.26	Yes	No	0	6	6
266	R:R:A26	R:R:G65	1.95	No	No	0	7	8
267	R:R:G167	R:R:S154	1.86	No	Yes	0	6	8
268	R:R:G161	R:R:S162	1.86	No	No	0	1	3
269	R:R:A100	R:R:A143	1.79	No	No	0	8	8
270	R:R:G83	R:R:I86	1.76	No	No	0	7	5
271	R:R:G167	R:R:K158	1.74	No	Yes	0	6	6
272	R:R:G32	R:R:L31	1.71	No	No	0	8	4
273	R:R:G310	R:R:L309	1.71	No	No	0	6	8
274	R:R:A332	R:R:S330	1.71	No	No	0	1	2
275	R:R:A19	R:R:V16	1.7	No	No	0	5	5
276	R:R:L145	R:R:P149	1.64	No	No	0	4	8
277	R:R:E160	R:R:G161	1.64	No	No	0	3	1
278	R:R:A19	R:R:I73	1.62	No	No	0	5	6
279	R:R:A176	R:R:I324	1.62	No	No	0	6	6
280	R:R:V129	R:R:V133	1.6	No	No	0	4	3
281	R:R:V133	R:R:V137	1.6	No	No	0	3	4
282	R:R:V137	R:R:V141	1.6	No	No	0	4	4
283	R:R:T92	R:R:V88	1.59	No	No	0	6	7
284	R:R:T124	R:R:V120	1.59	No	No	0	5	7
285	R:R:G128	R:R:H126	1.59	No	No	0	4	7
286	R:R:I307	R:R:V311	1.54	No	No	0	7	6
287	R:R:L305	R:R:S304	1.5	Yes	No	0	8	8
288	R:R:L326	R:R:S330	1.5	No	No	0	5	2
289	R:R:N118	R:R:S121	1.49	No	No	0	6	5
290	R:R:I177	R:R:L181	1.43	No	No	0	5	5
291	R:R:D159	R:R:E160	1.3	No	No	0	4	3
292	R:R:H292	R:R:L296	1.29	No	No	0	5	4
293	R:R:F82	R:R:K84	1.24	Yes	No	0	6	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	13.5638	8	1	0
2	R:R:F40	10.2525	4	2	8
3	R:R:L46	7.6925	4	2	9
4	R:R:R49	7.194	5	3	7
5	R:R:Y52	7.0275	4	2	6
6	R:R:F53	8.0275	4	3	8
7	R:R:F54	8.015	4	0	8
8	R:R:N56	10.22	4	7	9
9	R:R:D61	9.38	4	0	9
10	R:R:F62	5.29	4	0	8
11	R:R:F63	5.69	4	0	6
12	R:R:I69	6.47	4	1	8
13	R:R:Y72	10.524	5	1	7
14	R:R:F82	5.43667	6	4	6
15	R:R:Y95	9.4	5	1	8
16	R:R:Y113	8.56	4	5	9
17	R:R:Y122	9.515	4	3	8
18	R:R:N147	7.258	5	1	8
19	R:R:I151	5.025	4	1	7
20	R:R:S154	6.2575	4	0	8
21	R:R:K158	4.345	4	4	6
22	R:R:P166	11.03	5	1	7
23	R:R:F168	5.338	5	0	6
24	R:R:F183	4.62	5	1	9
25	R:R:V190	3.6425	4	0	9
26	R:R:F193	6.845	4	5	7
27	R:R:Y198	3.5225	4	0	7
28	R:R:R297	4.6775	4	0	7
29	R:R:L305	5.95	4	0	8
30	R:R:F312	5.73	5	1	9
31	R:R:W316	10.3514	7	1	9
32	R:R:Y319	8.955	6	1	7
33	R:R:K336	10.5225	4	1	4
34	R:R:F344	10.32	5	1	6
35	R:R:W345	8.448	5	1	8
36	R:R:W348	9.86714	7	1	8
37	R:R:N354	7.228	5	0	9
38	R:R:Y358	8.7475	4	6	9
39	R:R:F365	6.666	5	2	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:F344	14.2931	24.07	Yes	Yes	1	0	6
2	R:R:F344	R:R:Y72	13.9247	8.25	Yes	Yes	1	6	7
3	R:R:T76	R:R:Y72	24.6489	21.22	No	Yes	0	5	7
4	R:R:L77	R:R:T76	21.5404	4.42	No	No	0	6	5
5	R:R:L18	R:R:L77	29.254	4.15	No	No	0	5	6
6	R:R:L18	R:R:R15	24.6892	13.36	No	No	0	5	3
7	L:L:?1	R:R:W348	47.6917	11.79	Yes	Yes	1	0	8
8	R:R:W348	R:R:Y72	15.3005	6.75	Yes	Yes	1	8	7
9	R:R:W345	R:R:W348	35.8738	12.18	Yes	Yes	1	8	8
10	R:R:M22	R:R:W345	27.6307	13.96	No	Yes	0	7	8
11	R:R:L77	R:R:M22	12.4971	7.07	No	No	0	6	7
12	R:R:R15	R:R:T17	19.7732	3.88	No	No	0	3	3
13	R:R:F21	R:R:T17	14.8457	3.89	No	No	0	4	3
14	R:R:I73	R:R:M22	13.7405	4.37	No	No	0	6	7
15	L:L:?1	R:R:W316	88.0382	4.29	Yes	Yes	1	0	9
16	R:R:N350	R:R:W316	99.4934	6.78	No	Yes	0	9	9
17	R:R:N350	R:R:N354	97.4787	12.26	No	Yes	0	9	9
18	R:R:D61	R:R:N354	28.189	4.04	Yes	Yes	0	9	9
19	R:R:V64	R:R:W348	22.8011	6.13	No	Yes	0	8	8
20	R:R:S351	R:R:V64	22.0009	6.46	No	No	0	9	8
21	R:R:D61	R:R:S351	21.5577	11.78	Yes	No	0	9	9
22	R:R:D61	R:R:I29	10.0794	4.2	Yes	No	0	9	8
23	R:R:I105	R:R:N354	100	8.5	No	Yes	0	9	9
24	R:R:I105	R:R:Y358	98.653	10.88	No	Yes	0	9	9
25	R:R:I108	R:R:Y358	87.4971	7.25	No	Yes	6	9	9
26	R:R:F54	R:R:I108	86.3861	8.79	Yes	No	0	8	9
27	R:R:F365	R:R:F54	57.7193	7.5	Yes	Yes	0	8	8
28	R:R:F365	R:R:S51	44.8595	5.28	Yes	No	2	8	9
29	R:R:F40	R:R:S51	44.7271	5.28	Yes	No	2	8	9
30	R:R:F40	R:R:L55	38.8959	14.61	Yes	No	0	8	7
31	R:R:I37	R:R:L55	25.3742	4.28	No	No	0	8	7
32	R:R:F62	R:R:I37	23.4861	3.77	Yes	No	0	8	8
33	R:R:F62	R:R:V66	20.038	7.87	Yes	No	0	8	5
34	R:R:M30	R:R:V66	18.0636	4.56	No	No	0	6	5
35	L:L:?1	R:R:Y95	62.6238	18.76	Yes	Yes	1	0	8
36	R:R:I151	R:R:Y95	19.4681	4.84	Yes	Yes	1	7	8
37	R:R:I151	R:R:T92	28.1948	3.04	Yes	No	0	7	6
38	R:R:F144	R:R:T92	24.2229	2.59	No	No	0	5	6
39	R:R:F144	R:R:P149	22.3233	5.78	No	No	0	5	8
40	R:R:L145	R:R:P149	21.385	1.64	No	No	0	4	8
41	R:R:L145	R:R:V141	20.4927	2.98	No	No	0	4	4
42	R:R:V137	R:R:V141	19.635	1.6	No	No	0	4	4
43	R:R:V133	R:R:V137	18.8407	1.6	No	No	0	3	4
44	R:R:V129	R:R:V133	18.1672	1.6	No	No	0	4	3
45	R:R:V129	R:R:Y52	17.7757	5.05	No	Yes	0	4	6
46	R:R:F40	R:R:Y52	20.4467	7.22	Yes	Yes	2	8	6
47	R:R:F27	R:R:M30	16.0776	2.49	No	No	0	5	6
48	R:R:F27	R:R:L31	14.0801	3.65	No	No	0	5	4
49	R:R:L31	R:R:L35	10.0507	2.77	No	No	0	4	8
50	R:R:F54	R:R:H362	25.8635	5.66	Yes	No	0	8	9
51	R:R:H362	R:R:R364	23.9408	6.77	No	No	0	9	7
52	R:R:H48	R:R:R364	20.8324	4.51	No	No	0	7	7
53	R:R:H48	R:R:Y122	17.9887	8.71	No	Yes	0	7	8
54	R:R:I132	R:R:Y52	18.5874	9.67	No	Yes	0	7	6
55	R:R:R49	R:R:Y122	11.0465	5.14	Yes	Yes	3	7	8
56	R:R:I59	R:R:L55	11.6682	7.14	No	No	0	6	7
57	R:R:N147	R:R:V146	20.1071	7.39	Yes	No	0	8	7
58	R:R:V146	R:R:Y103	15.6344	3.79	No	No	0	7	7
59	R:R:V139	R:R:Y103	12.6122	3.79	No	No	0	8	7
60	R:R:P166	R:R:Y95	35.6205	11.13	Yes	Yes	1	7	8
61	R:R:F168	R:R:P166	45.5388	10.11	Yes	Yes	0	6	7
62	R:R:F168	R:R:S154	55.2671	2.64	Yes	Yes	0	6	8
63	R:R:G167	R:R:S154	47.2082	1.86	No	Yes	0	6	8
64	R:R:G167	R:R:K158	45.1646	1.74	No	Yes	0	6	6
65	R:R:C87	R:R:K158	17.3785	3.23	No	Yes	4	9	6
66	R:R:C87	R:R:F82	15.4271	8.38	No	Yes	4	9	6
67	R:R:C164	R:R:K158	17.3901	3.23	No	Yes	4	9	6
68	R:R:C164	R:R:F82	15.4271	4.19	No	Yes	4	9	6
69	R:R:E182	R:R:W316	32.184	11.99	No	Yes	1	8	9
70	R:R:F312	R:R:W316	49.4934	6.01	Yes	Yes	1	9	9
71	R:R:V102	R:R:W316	37.0424	9.81	No	Yes	1	8	9
72	R:R:P186	R:R:V102	39.5637	3.53	No	No	0	9	8
73	R:R:P186	R:R:V106	30.5549	3.53	No	No	0	9	7
74	R:R:L189	R:R:V106	28.7186	2.98	No	No	0	7	7
75	R:R:F193	R:R:L189	26.8708	3.65	Yes	No	0	7	7
76	R:R:F193	R:R:Y113	13.6542	8.25	Yes	Yes	5	7	9
77	R:R:N147	R:R:T178	22.8068	4.39	Yes	No	0	8	8
78	L:L:?1	R:R:Y319	33.3468	8.83	Yes	Yes	1	0	7
79	R:R:Y319	R:R:Y340	31.4126	14.89	Yes	No	0	7	5
80	R:R:K336	R:R:Y340	10.0161	11.94	Yes	No	0	4	5
81	R:R:T323	R:R:Y319	26.3585	8.74	No	Yes	0	7	7
82	R:R:L175	R:R:T323	23.7739	8.84	No	No	0	7	7
83	R:R:L175	R:R:S327	10.6781	3	No	No	0	7	6
84	R:R:I324	R:R:L175	10.6781	4.28	No	No	0	6	7
85	R:R:F312	R:R:V190	50.6505	3.93	Yes	Yes	0	9	9
86	R:R:N194	R:R:V190	42.1598	4.43	No	Yes	0	9	9
87	R:R:L305	R:R:N194	40.4271	8.24	Yes	No	0	8	9
88	R:R:L301	R:R:L305	31.758	6.92	No	Yes	0	8	8
89	R:R:L301	R:R:Y198	11.7085	5.86	No	Yes	0	8	7
90	R:R:L201	R:R:L301	19.117	4.15	No	No	0	8	8
91	R:R:L201	R:R:R297	17.4476	3.64	No	Yes	0	8	7
92	R:R:E294	R:R:R297	11.7373	5.82	No	Yes	0	5	7
93	R:R:L308	R:R:Y358	12.6295	11.72	No	Yes	0	8	9
94	R:R:L308	R:R:L357	10.5169	5.54	No	No	0	8	8
95	R:R:F322	R:R:Y340	22.7435	7.22	No	No	0	6	5
96	R:R:F322	R:R:S337	11.461	2.64	No	No	0	6	2
97	R:R:E182	R:R:N147	29.8469	10.52	No	Yes	1	8	8
98	R:R:Q347	R:R:W316	21.0338	29.57	No	Yes	1	8	9
99	R:R:Q347	R:R:Y319	20.3431	9.02	No	Yes	1	8	7
100	R:R:F168	R:R:T178	21.7131	5.19	Yes	No	0	6	8
101	R:R:I151	R:R:P166	10.4478	5.08	Yes	Yes	1	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D94	12.77	1	Yes	No	0	8	0	1
L:L:?1	R:R:Y95	18.76	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:C98	10.46	1	Yes	No	0	8	0	1
L:L:?1	R:R:W316	4.29	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:Y319	8.83	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:F344	24.07	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:Q347	17.54	1	Yes	No	0	8	0	1
L:L:?1	R:R:W348	11.79	1	Yes	Yes	0	8	0	1
R:R:V64	R:R:W348	6.13	0	No	Yes	8	8	2	1
R:R:D94	R:R:S68	8.83	1	No	No	8	8	1	2
R:R:I69	R:R:W345	4.7	1	Yes	Yes	8	8	2	2
R:R:I69	R:R:W348	12.92	1	Yes	Yes	8	8	2	1
R:R:W90	R:R:Y72	8.68	1	No	Yes	7	7	2	2
R:R:F344	R:R:Y72	8.25	1	Yes	Yes	6	7	1	2
R:R:W345	R:R:Y72	7.72	1	Yes	Yes	8	7	2	2
R:R:W348	R:R:Y72	6.75	1	Yes	Yes	8	7	1	2
R:R:F344	R:R:W90	4.01	1	Yes	No	6	7	1	2
R:R:D94	R:R:W348	12.28	1	No	Yes	8	8	1	1
R:R:N147	R:R:Y95	8.14	1	Yes	Yes	8	8	2	1
R:R:I151	R:R:Y95	4.84	1	Yes	Yes	7	8	2	1
R:R:P166	R:R:Y95	11.13	1	Yes	Yes	7	8	2	1
R:R:F169	R:R:Y95	4.13	1	No	Yes	6	8	2	1
R:R:F312	R:R:V102	9.18	1	Yes	No	9	8	2	2
R:R:V102	R:R:W316	9.81	1	No	Yes	8	9	2	1
R:R:E182	R:R:N147	10.52	1	No	Yes	8	8	2	2
R:R:I151	R:R:P166	5.08	1	Yes	Yes	7	7	2	2
R:R:F169	R:R:P166	17.34	1	No	Yes	6	7	2	2
R:R:E182	R:R:W316	11.99	1	No	Yes	8	9	2	1
R:R:F183	R:R:F312	4.29	1	Yes	Yes	9	9	2	2
R:R:F183	R:R:W316	4.01	1	Yes	Yes	9	9	2	1
R:R:F312	R:R:W316	6.01	1	Yes	Yes	9	9	2	1
R:R:Q347	R:R:W316	29.57	1	No	Yes	8	9	1	1
R:R:N350	R:R:W316	6.78	0	No	Yes	9	9	2	1
R:R:T323	R:R:Y319	8.74	0	No	Yes	7	7	2	1
R:R:Y319	R:R:Y340	14.89	1	Yes	No	7	5	1	2
R:R:A343	R:R:Y319	4	0	No	Yes	5	7	2	1
R:R:F344	R:R:Y319	8.25	1	Yes	Yes	6	7	1	1
R:R:Q347	R:R:Y319	9.02	1	No	Yes	8	7	1	1
R:R:F344	R:R:W348	7.02	1	Yes	Yes	6	8	1	1
R:R:W345	R:R:W348	12.18	1	Yes	Yes	8	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9L42_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.77
Number of Linked Nodes	256
Number of Links	293
Number of Hubs	39
Number of Links mediated by Hubs	151
Number of Communities	9
Number of Nodes involved in Communities	58
Number of Links involved in Communities	80

Path Summary
Number Of Nodes in MetaPath	102
Number Of Links MetaPath	101
Number of Shortest Paths	51063
Length Of Smallest Path	3
Average Path Length	13.5493
Length of Longest Path	35
Minimum Path Strength	1.47
Average Path Strength	7.31081
Maximum Path Strength	21.415
Minimum Path Correlation	0.7
Average Path Correlation	0.927778
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	48.2568
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.3528
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	HSM
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	HSM
Name	Histamine
Synonyms	beta-aminoethylglyoxaline
Identifier
Formula	C5 H9 N3
Molecular Weight	111.145
SMILES
PubChem	774
Formal Charge	0
Total Atoms	17
Total Chiral Atoms	0
Total Bonds	17
Total Aromatic Bonds	5


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q9H3N8
Sequence	>9L42_nogp_Chain_R T R V T L A F F M S L V A F A I M L G N A L V I L A F V V D K N L R H R S S Y F F L N L A I S D F F V G V I S I P L Y I P H T L F E W D F G K E I C V F W L T T D Y L L C T A S V Y N I V L I S Y D R Y L S V S N A V S Y R T Q H T G V L K I V T L M V A V W V L A F L V N G P M I L V S E S W K D E G S E C E P G F F S E W Y I L A I T S F L E F V I P V I L V A Y F N M N I Y W S L W K R D E H V E L L R A R R L A K S L A I L L G V F A V C W A P Y S L F T I V L S F Y S S A P K S V W Y R I A F W L Q W F N S F V N P L L Y P L C H K R F Q K A F L K I F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	6WH4	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Methiothepin	-	-	3.4	2020-09-23	doi.org/10.1016/j.cell.2020.08.024
	8H4I	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs)/β1/γ2	3.06	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4I (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.06	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4K	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4K (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	GW9508	-		3.1	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4L	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.07	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8H4L (No Gprot)	A	Lipid	Free Fatty Acid	FFA4	Homo sapiens	Doconexent	-		3.07	2023-06-21	doi.org/10.1038/s41422-023-00835-x
	8KH4	A	Orphan	Orphan	GPR161	Homo sapiens	-	-	Gs/β1/γ2	3.1	2023-10-11	doi.org/10.1038/s41467-023-41654-3
	8KH4 (No Gprot)	A	Orphan	Orphan	GPR161	Homo sapiens	-	-		3.1	2023-10-11	doi.org/10.1038/s41467-023-41654-3
	7YFC	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3	2023-10-25	doi.org/10.1038/s41467-023-42260-z
	7YFC (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		3	2023-10-25	doi.org/10.1038/s41467-023-42260-z
	7YFD	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2023-10-25	doi.org/10.1038/s41467-023-42260-z
	7YFD (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-		3.1	2023-10-25	doi.org/10.1038/s41467-023-42260-z
	8HN8	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	Gi1/β1/γ2	3	2023-12-20	To be published
	8HN8 (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		3	2023-12-20	To be published
	8HOC	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-	Gi1/β1/γ2	3	2023-12-20	To be published
	8HOC (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-		3	2023-12-20	To be published
	8TH4	A	Peptide	Angiotensin	AT₁	Homo sapiens	Losartan	AT118-L Nanobody	-	3.3	2024-05-22	doi.org/10.1038/s41589-024-01620-6
	8YN9	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	Gi1/β1/γ2	2.3	2024-10-09	doi.org/10.1038/s41467-024-52585-y
	8YN9 (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		2.3	2024-10-09	doi.org/10.1038/s41467-024-52585-y
	8YNA	A	Amine	Histamine	H₄	Homo sapiens	Immepip	-	Gi1/β1/γ2	2.63	2024-10-16	doi.org/10.2210/pdb8YN7/pdb
	8YNA (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Immepip	-		2.63	2024-10-16	doi.org/10.2210/pdb8YN7/pdb
	9JED	A	Amine	Histamine	H₄	Homo sapiens	Histamine	PO4	Gi1/β1/γ2	2.58	2025-09-10	doi.org/10.1038/s41401-025-01633-4
	9JED (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	PO4		2.58	2025-09-10	doi.org/10.1038/s41401-025-01633-4
	9L42	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	Gi1/β1/γ2	2.9	2025-10-22	doi.org/10.3390/ph18030292
	9L42 (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		2.9	2025-10-22	doi.org/10.3390/ph18030292
	8JXT	A	Amine	Histamine	H₄	Homo sapiens	Histamine	PO4	Gi1/β1/γ2	3.07	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	8JXT (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	PO4		3.07	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	8JXV	A	Amine	Histamine	H₄	Homo sapiens	Clozapine	-	Gi1/β1/γ2	3.21	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	8JXV (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Clozapine	-		3.21	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	8JXW	A	Amine	Histamine	H₄	Homo sapiens	VUF6884	-	Gi1/β1/γ2	3.01	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	8JXW (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	VUF6884	-		3.01	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	8JXX	A	Amine	Histamine	H₄	Homo sapiens	Clobenpropit	-	Gi1/β1/γ2	3.06	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	8JXX (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Clobenpropit	-		3.06	2024-03-20	doi.org/10.1038/s41467-024-46840-5
	9LRC	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	-	2.84	2025-06-11	doi.org/10.1038/s42003-025-08363-7
	9LRE	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	Gi1/β1/γ2	2.84	2025-06-11	doi.org/10.1038/s42003-025-08363-7
	9LRE (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-		2.84	2025-06-11	doi.org/10.1038/s42003-025-08363-7
	9JG1	A	Amine	Histamine	H₄	Homo sapiens	Adriforant	-	-	3.62	2025-12-03	10.1038/s41401-025-01633-4
	9JG1 (No Gprot)	A	Amine	Histamine	H₄	Homo sapiens	Adriforant	-		3.62	2025-12-03	10.1038/s41401-025-01633-4

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