psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:Y1	R:R:D195	11.49	No	No	0	0	3
2	L:L:S2	R:R:D191	8.83	No	No	0	0	4
3	L:L:F3	R:R:R178	20.31	Yes	No	0	0	2
4	L:L:F3	R:R:L187	2.44	Yes	No	0	0	4
5	L:L:F3	R:R:G189	4.52	Yes	No	0	0	4
6	L:L:F3	R:R:D191	8.36	Yes	No	0	0	4
7	L:L:K4	R:R:P270	6.69	No	No	0	0	3
8	L:L:K4	R:R:F275	6.2	No	No	0	0	3
9	L:L:M6	L:L:P7	3.35	Yes	No	0	0	0
10	L:L:M6	L:L:R10	2.48	Yes	Yes	0	0	0
11	L:L:M6	R:R:V190	4.56	Yes	No	0	0	5
12	L:L:M6	R:R:M265	2.89	Yes	No	0	0	4
13	L:L:P7	R:R:D282	9.66	No	No	0	0	4
14	L:L:?9	L:L:L8	4.22	Yes	Yes	0	0	0
15	L:L:L8	R:R:I91	2.85	Yes	No	0	0	6
16	L:L:L8	R:R:W102	3.42	Yes	Yes	0	0	8
17	L:L:L8	R:R:P113	4.93	Yes	No	0	0	6
18	L:L:?9	L:L:R10	4.94	Yes	Yes	0	0	0
19	L:L:?9	R:R:L92	5.63	Yes	No	1	0	6
20	L:L:?9	R:R:I116	4.36	Yes	No	0	0	6
21	L:L:?9	R:R:Y290	3.58	Yes	Yes	1	0	7
22	L:L:R10	R:R:L117	3.64	Yes	No	0	0	4
23	L:L:R10	R:R:Y258	13.38	Yes	Yes	0	0	7
24	L:L:R10	R:R:G262	3	Yes	No	0	0	5
25	L:L:R10	R:R:D282	15.48	Yes	No	0	0	4
26	R:R:H99	R:R:L33	2.57	No	No	0	2	4
27	R:R:P36	R:R:V35	5.3	No	No	0	3	3
28	R:R:D37	R:R:S283	2.94	No	No	0	4	4
29	R:R:A40	R:R:S287	3.42	No	Yes	0	6	4
30	R:R:F93	R:R:L41	8.53	No	No	0	7	5
31	R:R:I43	R:R:S287	7.74	No	Yes	0	5	4
32	R:R:F44	R:R:L89	2.44	Yes	Yes	1	7	7
33	R:R:F44	R:R:L92	4.87	Yes	No	1	7	6
34	R:R:F44	R:R:S287	3.96	Yes	Yes	0	7	4
35	R:R:F44	R:R:Y290	5.16	Yes	Yes	1	7	7
36	R:R:C86	R:R:V47	1.71	No	No	1	5	6
37	R:R:L89	R:R:V47	2.98	Yes	No	1	7	6
38	R:R:C294	R:R:V47	6.83	No	No	0	7	6
39	R:R:F48	R:R:V52	3.93	No	No	0	6	5
40	R:R:F48	R:R:L89	7.31	No	Yes	0	6	7
41	R:R:F48	R:R:P90	7.22	No	No	0	6	9
42	R:R:C294	R:R:V50	5.12	No	No	0	7	6
43	R:R:G51	R:R:N55	1.7	No	Yes	0	8	9
44	R:R:C86	R:R:G51	1.96	No	No	0	5	8
45	R:R:G54	R:R:L53	1.71	No	No	0	7	4
46	R:R:D82	R:R:N55	17.5	No	Yes	0	9	9
47	R:R:F83	R:R:N55	2.42	No	Yes	0	8	9
48	R:R:N55	R:R:P297	13.03	Yes	No	0	9	9
49	R:R:L311	R:R:L57	4.15	No	No	0	6	5
50	R:R:A79	R:R:V58	3.39	No	No	0	8	8
51	R:R:P297	R:R:V58	1.77	No	No	0	9	8
52	R:R:V58	R:R:Y300	3.79	No	No	0	8	9
53	R:R:A79	R:R:V59	1.7	No	No	0	8	7
54	R:R:F64	R:R:W60	13.03	No	No	5	4	4
55	R:R:S314	R:R:W60	2.47	No	No	5	4	4
56	R:R:F307	R:R:V61	6.55	No	No	0	9	6
57	R:R:L311	R:R:V61	2.98	No	No	0	6	6
58	R:R:L76	R:R:T62	4.42	No	No	0	6	6
59	R:R:T62	R:R:Y300	3.75	No	No	0	6	9
60	R:R:F64	R:R:S314	5.28	No	No	5	4	4
61	R:R:E65	R:R:R68	4.65	No	No	0	5	7
62	R:R:A72	R:R:E65	3.02	No	No	0	7	5
63	R:R:E65	R:R:R310	2.33	No	No	0	5	4
64	R:R:A66	R:R:K67	3.21	No	No	0	5	6
65	R:R:R68	R:R:T69	3.88	No	No	0	7	7
66	R:R:I70	R:R:R148	3.76	No	Yes	3	6	7
67	R:R:G149	R:R:I70	3.53	No	No	3	5	6
68	R:R:N71	R:R:R148	3.62	No	Yes	0	7	7
69	R:R:A153	R:R:I73	4.87	No	No	0	7	6
70	R:R:I73	R:R:W154	17.62	No	No	0	6	3
71	R:R:T129	R:R:W74	4.85	No	Yes	0	6	7
72	R:R:I130	R:R:W74	4.7	No	Yes	0	8	7
73	R:R:D133	R:R:W74	10.05	No	Yes	0	8	7
74	R:R:A153	R:R:W74	5.19	No	Yes	0	7	7
75	R:R:A156	R:R:W74	2.59	No	Yes	0	5	7
76	R:R:F75	R:R:Y300	16.5	No	No	0	8	9
77	R:R:L126	R:R:N77	2.75	No	Yes	6	7	9
78	R:R:N77	R:R:W154	2.26	Yes	No	0	9	3
79	R:R:C157	R:R:N77	9.45	No	Yes	6	6	9
80	R:R:N77	R:R:W161	5.65	Yes	Yes	0	9	9
81	R:R:L78	R:R:S123	3	No	No	0	9	9
82	R:R:A81	R:R:W161	2.59	No	Yes	0	8	9
83	R:R:C293	R:R:D82	7.78	No	No	0	8	9
84	R:R:F83	R:R:L87	13.4	No	No	0	8	4
85	R:R:L84	R:R:N119	5.49	No	No	0	6	9
86	R:R:N119	R:R:S85	4.47	No	No	0	9	6
87	R:R:C293	R:R:S85	1.72	No	No	0	8	6
88	R:R:C86	R:R:L89	3.17	No	Yes	1	5	7
89	R:R:A88	R:R:I116	3.25	No	No	0	6	6
90	R:R:L89	R:R:Y290	2.34	Yes	Yes	1	7	7
91	R:R:L92	R:R:Y290	3.52	No	Yes	1	6	7
92	R:R:F93	R:R:V97	3.93	No	No	0	7	3
93	R:R:I96	R:R:S283	3.1	No	No	0	5	4
94	R:R:Q98	R:R:V97	2.87	No	No	0	4	3
95	R:R:H101	R:R:P103	10.68	No	No	0	4	3
96	R:R:H101	R:R:V186	5.54	No	No	0	4	6
97	R:R:F104	R:R:W102	4.01	No	Yes	2	7	8
98	R:R:A108	R:R:W102	3.89	No	Yes	2	5	8
99	R:R:C109	R:R:W102	5.22	Yes	Yes	2	9	8
100	R:R:L112	R:R:W102	2.28	No	Yes	0	5	8
101	R:R:C188	R:R:W102	6.53	No	Yes	2	9	8
102	R:R:A108	R:R:F104	4.16	No	No	2	5	7
103	R:R:G105	R:R:G106	2.11	No	No	0	7	3
104	R:R:G106	R:R:V177	1.84	No	No	0	3	4
105	R:R:C109	R:R:R175	2.79	Yes	Yes	2	9	5
106	R:R:C109	R:R:V177	3.42	Yes	No	0	9	4
107	R:R:C109	R:R:C188	7.28	Yes	No	2	9	9
108	R:R:P113	R:R:S171	1.78	No	No	0	6	5
109	R:R:P113	R:R:R175	7.21	No	Yes	0	6	5
110	R:R:S114	R:R:T168	3.2	No	No	0	5	6
111	R:R:F172	R:R:S114	6.61	No	No	0	4	5
112	R:R:L117	R:R:S171	3	No	No	0	4	5
113	R:R:L118	R:R:W161	2.28	No	Yes	0	5	9
114	R:R:L118	R:R:T168	7.37	No	No	0	5	6
115	R:R:N119	R:R:W161	2.26	No	Yes	0	9	9
116	R:R:M120	R:R:W255	3.49	No	Yes	1	7	9
117	R:R:M120	R:R:Y258	2.39	No	Yes	1	7	7
118	R:R:M120	R:R:Y290	3.59	No	Yes	1	7	7
119	R:R:L167	R:R:Y121	8.21	No	No	0	4	7
120	R:R:R206	R:R:Y121	3.09	No	No	0	6	7
121	R:R:A122	R:R:W161	7.78	No	Yes	0	6	9
122	R:R:A122	R:R:A164	1.79	No	No	0	6	7
123	R:R:I124	R:R:P214	3.39	No	No	0	8	9
124	R:R:F251	R:R:I124	2.51	Yes	No	0	9	8
125	R:R:I124	R:R:W255	9.4	No	Yes	0	8	9
126	R:R:C157	R:R:L126	3.17	No	No	6	6	7
127	R:R:A160	R:R:L126	3.15	No	No	0	6	7
128	R:R:F251	R:R:L127	2.44	Yes	No	0	9	8
129	R:R:L127	R:R:N296	4.12	No	No	0	8	9
130	R:R:A128	R:R:P214	1.87	No	No	0	7	9
131	R:R:I130	R:R:R134	5.01	No	No	0	8	9
132	R:R:L218	R:R:S131	3	No	No	7	8	9
133	R:R:C221	R:R:S131	3.44	No	No	0	6	9
134	R:R:S131	R:R:Y222	12.72	No	Yes	7	9	8
135	R:R:D133	R:R:L137	4.07	No	No	3	8	8
136	R:R:D133	R:R:R148	5.96	No	Yes	3	8	7
137	R:R:R134	R:R:Y222	5.14	No	Yes	0	9	8
138	R:R:F135	R:R:F139	17.15	Yes	Yes	8	8	7
139	R:R:C221	R:R:F135	4.19	No	Yes	0	6	8
140	R:R:F135	R:R:F224	5.36	Yes	No	8	8	3
141	R:R:F135	R:R:I225	2.51	Yes	No	0	8	8
142	R:R:L137	R:R:R148	10.93	No	Yes	3	8	7
143	R:R:F139	R:R:V138	3.93	Yes	No	0	7	8
144	R:R:I225	R:R:V138	7.68	No	No	0	8	8
145	R:R:F139	R:R:F224	2.14	Yes	No	8	7	3
146	R:R:F139	R:R:R228	12.83	Yes	No	0	7	5
147	R:R:K140	R:R:W143	3.48	No	No	0	6	5
148	R:R:F147	R:R:W143	18.04	No	No	0	4	5
149	R:R:F147	R:R:N146	4.83	No	No	0	4	5
150	R:R:G149	R:R:R148	3	No	Yes	3	5	7
151	R:R:A150	R:R:W154	2.59	No	No	0	3	3
152	R:R:I169	R:R:L165	2.85	Yes	No	0	3	4
153	R:R:L167	R:R:L209	11.07	No	No	0	4	4
154	R:R:I169	R:R:P170	3.39	Yes	No	0	3	8
155	R:R:I169	R:R:L173	2.85	Yes	No	0	3	4
156	R:R:L173	R:R:Y174	3.52	No	No	0	4	4
157	R:R:Y174	R:R:Y192	5.96	No	No	0	4	5
158	R:R:R198	R:R:Y174	7.2	No	No	0	3	4
159	R:R:C188	R:R:R175	8.36	No	Yes	2	9	5
160	R:R:G189	R:R:R175	3	No	Yes	0	4	5
161	R:R:R175	R:R:V190	3.92	Yes	No	0	5	5
162	R:R:E179	R:R:P184	7.86	No	No	0	2	5
163	R:R:E179	R:R:V186	8.56	No	No	0	2	6
164	R:R:E180	R:R:P183	9.43	No	Yes	0	1	4
165	R:R:F182	R:R:Y181	6.19	No	No	0	3	1
166	R:R:F182	R:R:P183	5.78	No	Yes	0	3	4
167	R:R:P183	R:R:P184	1.95	Yes	No	0	4	5
168	R:R:E199	R:R:Y192	17.96	No	No	0	4	5
169	R:R:K196	R:R:S193	3.06	No	No	0	2	4
170	R:R:D195	R:R:H194	16.39	No	No	0	3	1
171	R:R:I204	R:R:R200	12.53	No	No	0	3	3
172	R:R:F267	R:R:R200	11.76	No	No	0	4	3
173	R:R:R206	R:R:V202	2.62	No	No	0	6	5
174	R:R:A203	R:R:S266	3.42	No	No	0	5	5
175	R:R:L207	R:R:Q259	6.65	No	Yes	0	5	8
176	R:R:F211	R:R:F251	3.22	Yes	Yes	0	8	9
177	R:R:F211	R:R:W255	3.01	Yes	Yes	1	8	9
178	R:R:F211	R:R:L256	2.44	Yes	No	0	8	5
179	R:R:F211	R:R:Q259	7.03	Yes	Yes	1	8	8
180	R:R:P214	R:R:W213	2.7	No	No	0	9	5
181	R:R:T217	R:R:W213	6.06	No	No	0	5	5
182	R:R:F251	R:R:L215	2.44	Yes	No	0	9	5
183	R:R:F252	R:R:L215	4.87	No	No	0	5	5
184	R:R:L218	R:R:Y222	4.69	No	Yes	7	8	8
185	R:R:F224	R:R:I220	2.51	No	No	0	3	3
186	R:R:V244	R:R:Y222	12.62	No	Yes	0	7	8
187	R:R:V248	R:R:Y222	2.52	No	Yes	0	7	8
188	R:R:L226	R:R:T240	2.95	No	No	0	5	7
189	R:R:L226	R:R:V244	5.96	No	No	0	5	7
190	R:R:T229	R:R:W230	2.43	No	No	0	8	4
191	R:R:T229	R:R:T235	3.14	No	No	0	8	4
192	R:R:T238	R:R:W230	2.43	No	No	0	5	4
193	R:R:R232	R:R:S231	2.64	No	No	0	5	4
194	R:R:K239	R:R:S237	3.06	No	No	0	7	7
195	R:R:A303	R:R:K239	3.21	No	No	0	6	7
196	R:R:A249	R:R:V245	1.7	No	No	0	4	4
197	R:R:F251	R:R:N292	4.83	Yes	Yes	0	9	9
198	R:R:F252	R:R:L256	4.87	No	No	0	5	5
199	R:R:F254	R:R:I253	2.51	Yes	No	0	8	5
200	R:R:F254	R:R:F288	7.5	Yes	No	4	8	8
201	R:R:F254	R:R:I291	10.05	Yes	No	4	8	5
202	R:R:F254	R:R:N292	4.83	Yes	Yes	0	8	9
203	R:R:F254	R:R:I295	2.51	Yes	No	4	8	7
204	R:R:W255	R:R:Y258	1.93	Yes	Yes	1	9	7
205	R:R:Q259	R:R:W255	2.19	Yes	Yes	1	8	9
206	R:R:N292	R:R:W255	7.91	Yes	Yes	0	9	9
207	R:R:C285	R:R:P257	1.88	No	No	0	6	9
208	R:R:F288	R:R:P257	2.89	No	No	0	8	9
209	R:R:Q259	R:R:Y258	2.25	Yes	Yes	1	8	7
210	R:R:V286	R:R:Y258	2.52	No	Yes	0	5	7
211	R:R:A289	R:R:Y258	4	No	Yes	0	8	7
212	R:R:L278	R:R:T261	2.95	Yes	No	0	4	4
213	R:R:C285	R:R:T261	6.76	No	No	0	6	4
214	R:R:L278	R:R:M264	2.83	Yes	No	0	4	4
215	R:R:L278	R:R:M265	5.65	Yes	No	0	4	4
216	R:R:D282	R:R:M265	5.54	No	No	0	4	4
217	R:R:L268	R:R:S272	4.5	No	Yes	9	2	4
218	R:R:L268	R:R:T274	7.37	No	No	9	2	1
219	R:R:E269	R:R:P270	3.14	No	No	0	3	3
220	R:R:P273	R:R:S272	3.56	No	Yes	0	2	4
221	R:R:S272	R:R:T274	3.2	Yes	No	9	4	1
222	R:R:F275	R:R:S272	3.96	No	Yes	0	3	4
223	R:R:L278	R:R:T274	2.95	Yes	No	0	4	1
224	R:R:F275	R:R:K279	3.72	No	No	0	3	4
225	R:R:K280	R:R:L277	2.82	No	No	0	2	1
226	R:R:L277	R:R:L281	2.77	No	No	0	1	5
227	R:R:L284	R:R:S287	4.5	No	Yes	0	4	4
228	R:R:V286	R:R:Y290	6.31	No	Yes	0	5	7
229	R:R:F288	R:R:I291	3.77	No	No	4	8	5
230	R:R:I291	R:R:I295	2.94	No	No	4	5	7
231	R:R:N292	R:R:N296	6.81	Yes	No	0	9	9
232	R:R:F307	R:R:V301	7.87	No	No	0	9	6
233	R:R:F307	R:R:R310	9.62	No	No	0	9	4
234	R:R:G309	R:R:Q308	4.93	No	No	0	5	8
235	L:L:K4	L:L:P5	1.67	No	No	0	0	0
236	R:R:K140	R:R:P141	1.67	No	No	0	6	8
237	R:R:K185	R:R:P183	1.67	No	Yes	0	3	4
238	R:R:G304	R:R:Q305	1.64	No	No	0	8	6
239	R:R:G306	R:R:Q305	1.64	No	No	0	7	6
240	R:R:A107	R:R:I111	1.62	No	No	0	1	4
241	R:R:A246	R:R:I299	1.62	No	No	0	5	7
242	R:R:V42	R:R:V46	1.6	No	No	0	5	4
243	R:R:V46	R:R:V50	1.6	No	No	0	4	6
244	R:R:S95	R:R:T94	1.6	No	No	0	4	3
245	R:R:V243	R:R:V244	1.6	No	No	0	7	7
246	R:R:V243	R:R:V247	1.6	No	No	10	7	7
247	R:R:V247	R:R:V248	1.6	No	No	0	7	7
248	R:R:T62	R:R:V61	1.59	No	No	0	6	6
249	R:R:T219	R:R:V248	1.59	No	No	0	4	7
250	R:R:T261	R:R:V260	1.59	No	No	0	4	6
251	R:R:A160	R:R:L125	1.58	No	No	0	6	6
252	R:R:A164	R:R:L125	1.58	No	No	0	7	6
253	R:R:T219	R:R:T223	1.57	No	No	0	4	2
254	R:R:I155	R:R:V159	1.54	No	No	0	2	1
255	R:R:I204	R:R:V208	1.54	No	No	0	3	4
256	R:R:I299	R:R:V243	1.54	No	No	10	7	7
257	R:R:I299	R:R:V247	1.54	No	No	10	7	7
258	R:R:I298	R:R:V302	1.54	No	No	0	7	6
259	R:R:I225	R:R:T229	1.52	No	No	0	8	8
260	L:L:L8	R:R:S95	1.5	Yes	No	0	0	4
261	R:R:L53	R:R:V52	1.49	No	No	0	4	5
262	R:R:L84	R:R:V80	1.49	No	No	0	6	5
263	R:R:L163	R:R:V159	1.49	No	No	0	4	1
264	R:R:L167	R:R:V205	1.49	No	No	0	4	3
265	R:R:L212	R:R:V208	1.49	No	No	0	4	4
266	R:R:L241	R:R:V245	1.49	No	No	0	6	4
267	R:R:N292	R:R:S250	1.49	Yes	No	0	9	6
268	R:R:I204	R:R:I263	1.47	No	No	0	3	5
269	R:R:L227	R:R:T223	1.47	No	No	0	4	2
270	R:R:D191	R:R:V176	1.46	No	No	0	4	4
271	R:R:P36	R:R:R34	1.44	No	No	0	3	2
272	R:R:F104	R:R:P103	1.44	No	No	0	7	3
273	R:R:P170	R:R:R206	1.44	No	No	0	8	6
274	R:R:I38	R:R:L33	1.43	No	No	0	5	4
275	R:R:I130	R:R:L78	1.43	No	No	0	8	9
276	R:R:I111	R:R:L115	1.43	No	No	0	4	5
277	R:R:I169	R:R:L166	1.43	Yes	No	0	3	4
278	R:R:I263	R:R:L207	1.43	No	No	0	5	5
279	R:R:I142	R:R:N146	1.42	No	No	0	5	5
280	R:R:L284	R:R:L39	1.38	No	No	0	4	5
281	R:R:L118	R:R:L165	1.38	No	No	0	5	4
282	R:R:L125	R:R:L163	1.38	No	No	0	6	4
283	R:R:H100	R:R:I96	1.33	No	No	0	4	5
284	R:R:R175	R:R:S110	1.32	Yes	No	0	5	6
285	R:R:C144	R:R:W143	1.31	No	No	0	5	5
286	R:R:F172	R:R:I111	1.26	No	No	0	4	4
287	R:R:H101	R:R:Q98	1.24	No	No	0	4	4
288	R:R:K196	R:R:R198	1.24	No	No	0	2	3
289	R:R:F267	R:R:R197	1.07	No	No	0	4	1
290	R:R:R236	R:R:W230	1	No	No	0	5	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:F3	8.9075	4	0	0
2	L:L:M6	3.32	4	0	0
3	L:L:L8	3.384	5	0	0
4	L:L:?9	4.546	5	1	0
5	L:L:R10	7.15333	6	0	0
6	R:R:F44	4.1075	4	1	7
7	R:R:N55	8.6625	4	0	9
8	R:R:W74	5.476	5	0	7
9	R:R:N77	5.0275	4	6	9
10	R:R:L89	3.648	5	1	7
11	R:R:W102	4.225	6	2	8
12	R:R:C109	4.6775	4	2	9
13	R:R:F135	7.3025	4	8	8
14	R:R:F139	9.0125	4	8	7
15	R:R:R148	5.454	5	3	7
16	R:R:W161	4.112	5	0	9
17	R:R:I169	2.63	4	0	3
18	R:R:R175	4.43333	6	2	5
19	R:R:P183	4.7075	4	0	4
20	R:R:F211	3.925	4	1	8
21	R:R:Y222	7.538	5	7	8
22	R:R:F251	3.088	5	0	9
23	R:R:F254	5.48	5	4	8
24	R:R:W255	4.655	6	1	9
25	R:R:Y258	4.41167	6	1	7
26	R:R:Q259	4.53	4	1	8
27	R:R:S272	3.805	4	9	4
28	R:R:L278	3.595	4	0	4
29	R:R:S287	4.905	4	0	4
30	R:R:Y290	4.08333	6	1	7
31	R:R:N292	5.174	5	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:K4	R:R:F275	10.8843	6.2	No	No	0	0	3
2	R:R:F275	R:R:S272	16.2769	3.96	No	Yes	0	3	4
3	R:R:S272	R:R:T274	21.5815	3.2	Yes	No	9	4	1
4	R:R:L278	R:R:T274	26.9301	2.95	Yes	No	0	4	1
5	R:R:L278	R:R:M265	38.7993	5.65	Yes	No	0	4	4
6	L:L:M6	R:R:M265	23.1167	2.89	Yes	No	0	0	4
7	L:L:M6	R:R:V190	10.4221	4.56	Yes	No	0	0	5
8	R:R:G189	R:R:R175	10.1634	3	No	Yes	0	4	5
9	L:L:M6	L:L:R10	24.8225	2.48	Yes	Yes	0	0	0
10	L:L:R10	R:R:D282	20.1618	15.48	Yes	No	0	0	4
11	R:R:D282	R:R:M265	18.1643	5.54	No	No	0	4	4
12	L:L:?9	L:L:L8	45.6777	4.22	Yes	Yes	0	0	0
13	L:L:?9	R:R:Y290	63.0606	3.58	Yes	Yes	1	0	7
14	L:L:R10	R:R:Y258	20.1673	13.38	Yes	Yes	0	0	7
15	R:R:F104	R:R:W102	27.0676	4.01	No	Yes	2	7	8
16	R:R:F104	R:R:P103	25.4168	1.44	No	No	0	7	3
17	R:R:H101	R:R:P103	23.6725	10.68	No	No	0	4	3
18	R:R:L89	R:R:Y290	98.0356	2.34	Yes	Yes	1	7	7
19	R:R:C86	R:R:L89	97.2101	3.17	No	Yes	1	5	7
20	R:R:C86	R:R:G51	100	1.96	No	No	0	5	8
21	R:R:G51	R:R:N55	99.6973	1.7	No	Yes	0	8	9
22	R:R:D82	R:R:N55	90.7995	17.5	No	Yes	0	9	9
23	R:R:N55	R:R:P297	25.3288	13.03	Yes	No	0	9	9
24	R:R:P297	R:R:V58	24.0026	1.77	No	No	0	9	8
25	R:R:V58	R:R:Y300	19.9472	3.79	No	No	0	8	9
26	R:R:T62	R:R:Y300	17.2949	3.75	No	No	0	6	9
27	R:R:T62	R:R:V61	14.5105	1.59	No	No	0	6	6
28	R:R:F307	R:R:V61	10.345	6.55	No	No	0	9	6
29	R:R:C293	R:R:D82	90.2548	7.78	No	No	0	8	9
30	R:R:C293	R:R:S85	89.699	1.72	No	No	0	8	6
31	R:R:N119	R:R:S85	89.1322	4.47	No	No	0	9	6
32	R:R:N119	R:R:W161	87.3659	2.26	No	Yes	0	9	9
33	R:R:N77	R:R:W161	61.2172	5.65	Yes	Yes	0	9	9
34	R:R:N77	R:R:W154	58.4383	2.26	Yes	No	0	9	3
35	R:R:I73	R:R:W154	56.4904	17.62	No	No	0	6	3
36	R:R:A153	R:R:I73	55.4614	4.87	No	No	0	7	6
37	R:R:A153	R:R:W74	54.4214	5.19	No	Yes	0	7	7
38	R:R:I130	R:R:W74	44.6211	4.7	No	Yes	0	8	7
39	R:R:H101	R:R:V186	14.7857	5.54	No	No	0	4	6
40	R:R:L118	R:R:W161	33.1591	2.28	No	Yes	0	5	9
41	R:R:M120	R:R:Y290	41.0004	3.59	No	Yes	1	7	7
42	R:R:W255	R:R:Y258	12.1609	1.93	Yes	Yes	1	9	7
43	R:R:L118	R:R:L165	24.1072	1.38	No	No	0	5	4
44	R:R:I169	R:R:L165	22.77	2.85	Yes	No	0	3	4
45	R:R:I169	R:R:P170	10.356	3.39	Yes	No	0	3	8
46	R:R:I124	R:R:W255	11.6547	9.4	No	Yes	0	8	9
47	R:R:Q259	R:R:Y258	20.2443	2.25	Yes	Yes	1	8	7
48	R:R:N292	R:R:W255	18.4449	7.91	Yes	Yes	0	9	9
49	R:R:I130	R:R:R134	41.182	5.01	No	No	0	8	9
50	R:R:R134	R:R:Y222	40.0704	5.14	No	Yes	0	9	8
51	R:R:S131	R:R:Y222	21.3449	12.72	No	Yes	7	9	8
52	R:R:C221	R:R:S131	20.0682	3.44	No	No	0	6	9
53	R:R:C221	R:R:F135	18.6981	4.19	No	Yes	0	6	8
54	R:R:F135	R:R:I225	10.1854	2.51	Yes	No	0	8	8
55	R:R:I169	R:R:L173	10.2405	2.85	Yes	No	0	3	4
56	R:R:E179	R:R:V186	12.9753	8.56	No	No	0	2	6
57	R:R:E179	R:R:P184	11.1539	7.86	No	No	0	2	5
58	R:R:L207	R:R:Q259	22.3133	6.65	No	Yes	0	5	8
59	R:R:I263	R:R:L207	19.562	1.43	No	No	0	5	5
60	R:R:I204	R:R:I263	16.7996	1.47	No	No	0	3	5
61	R:R:V248	R:R:Y222	10.0314	2.52	No	Yes	0	7	8
62	L:L:?9	L:L:R10	43.7792	4.94	Yes	Yes	0	0	0
63	L:L:L8	R:R:W102	31.987	3.42	Yes	Yes	0	0	8
64	R:R:M120	R:R:W255	32.3337	3.49	No	Yes	1	7	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Y1	R:R:D195	11.49	0	No	No	0	3	0	1
L:L:S2	R:R:D191	8.83	0	No	No	0	4	0	1
L:L:F3	R:R:R178	20.31	0	Yes	No	0	2	0	1
L:L:F3	R:R:L187	2.44	0	Yes	No	0	4	0	1
L:L:F3	R:R:G189	4.52	0	Yes	No	0	4	0	1
L:L:F3	R:R:D191	8.36	0	Yes	No	0	4	0	1
L:L:K4	R:R:P270	6.69	0	No	No	0	3	0	1
L:L:K4	R:R:F275	6.2	0	No	No	0	3	0	1
L:L:M6	R:R:V190	4.56	0	Yes	No	0	5	0	1
L:L:M6	R:R:M265	2.89	0	Yes	No	0	4	0	1
L:L:P7	R:R:D282	9.66	0	No	No	0	4	0	1
L:L:L8	R:R:I91	2.85	0	Yes	No	0	6	0	1
L:L:L8	R:R:W102	3.42	0	Yes	Yes	0	8	0	1
L:L:L8	R:R:P113	4.93	0	Yes	No	0	6	0	1
L:L:?9	R:R:L92	5.63	1	Yes	No	0	6	0	1
L:L:?9	R:R:I116	4.36	1	Yes	No	0	6	0	1
L:L:?9	R:R:Y290	3.58	1	Yes	Yes	0	7	0	1
L:L:R10	R:R:L117	3.64	0	Yes	No	0	4	0	1
L:L:R10	R:R:Y258	13.38	0	Yes	Yes	0	7	0	1
L:L:R10	R:R:G262	3	0	Yes	No	0	5	0	1
L:L:R10	R:R:D282	15.48	0	Yes	No	0	4	0	1
R:R:F44	R:R:L89	2.44	1	Yes	Yes	7	7	2	2
R:R:F44	R:R:L92	4.87	1	Yes	No	7	6	2	1
R:R:F44	R:R:Y290	5.16	1	Yes	Yes	7	7	2	1
R:R:A88	R:R:I116	3.25	0	No	No	6	6	2	1
R:R:L89	R:R:Y290	2.34	1	Yes	Yes	7	7	2	1
R:R:L92	R:R:Y290	3.52	1	No	Yes	6	7	1	1
R:R:F104	R:R:W102	4.01	2	No	Yes	7	8	2	1
R:R:A108	R:R:W102	3.89	2	No	Yes	5	8	2	1
R:R:C109	R:R:W102	5.22	2	Yes	Yes	9	8	2	1
R:R:L112	R:R:W102	2.28	0	No	Yes	5	8	2	1
R:R:C188	R:R:W102	6.53	2	No	Yes	9	8	2	1
R:R:A108	R:R:F104	4.16	2	No	No	5	7	2	2
R:R:C109	R:R:R175	2.79	2	Yes	Yes	9	5	2	2
R:R:C109	R:R:C188	7.28	2	Yes	No	9	9	2	2
R:R:P113	R:R:S171	1.78	0	No	No	6	5	1	2
R:R:P113	R:R:R175	7.21	0	No	Yes	6	5	1	2
R:R:L117	R:R:S171	3	0	No	No	4	5	1	2
R:R:M120	R:R:W255	3.49	1	No	Yes	7	9	2	2
R:R:M120	R:R:Y258	2.39	1	No	Yes	7	7	2	1
R:R:M120	R:R:Y290	3.59	1	No	Yes	7	7	2	1
R:R:C188	R:R:R175	8.36	2	No	Yes	9	5	2	2
R:R:G189	R:R:R175	3	0	No	Yes	4	5	1	2
R:R:R175	R:R:V190	3.92	2	Yes	No	5	5	2	1
R:R:D195	R:R:H194	16.39	0	No	No	3	1	1	2
R:R:W255	R:R:Y258	1.93	1	Yes	Yes	9	7	2	1
R:R:Q259	R:R:W255	2.19	1	Yes	Yes	8	9	2	2
R:R:Q259	R:R:Y258	2.25	1	Yes	Yes	8	7	2	1
R:R:V286	R:R:Y258	2.52	0	No	Yes	5	7	2	1
R:R:A289	R:R:Y258	4	0	No	Yes	8	7	2	1
R:R:L278	R:R:M265	5.65	0	Yes	No	4	4	2	1
R:R:D282	R:R:M265	5.54	0	No	No	4	4	1	1
R:R:E269	R:R:P270	3.14	0	No	No	3	3	2	1
R:R:F275	R:R:S272	3.96	0	No	Yes	3	4	1	2
R:R:F275	R:R:K279	3.72	0	No	No	3	4	1	2
R:R:V286	R:R:Y290	6.31	0	No	Yes	5	7	2	1
R:R:S95	R:R:T94	1.6	0	No	No	4	3	1	2
L:L:L8	R:R:S95	1.5	0	Yes	No	0	4	0	1
R:R:D191	R:R:V176	1.46	0	No	No	4	4	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9UMX_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	1.7
Number of Linked Nodes	271
Number of Links	290
Number of Hubs	31
Number of Links mediated by Hubs	123
Number of Communities	10
Number of Nodes involved in Communities	45
Number of Links involved in Communities	55

Path Summary
Number Of Nodes in MetaPath	65
Number Of Links MetaPath	64
Number of Shortest Paths	36607
Length Of Smallest Path	3
Average Path Length	15.6095
Length of Longest Path	37
Minimum Path Strength	1.345
Average Path Strength	4.85707
Maximum Path Strength	15.265
Minimum Path Correlation	0.7
Average Path Correlation	0.932172
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	57.6352
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.5593
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	DAL
PDB Residues	L:L:?9
Environment Details	Open EMBL-EBI Page
Code	DAL
Name	D-Alanine
Synonyms	D-Alanine
Identifier
Formula	C3 H7 N O2
Molecular Weight	89.093
SMILES
PubChem	71080
Formal Charge	0
Total Atoms	13
Total Chiral Atoms	1
Total Bonds	12
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P21730
Sequence	>9UMX_nogp_Chain_R T L R V P D I L A L V I F A V V F L V G V L G N A L V V W V T A F E A K R T I N A I W F L N L A V A D F L S C L A L P I L F T S I V Q H H H W P F G G A A C S I L P S L I L L N M Y A S I L L L A T I S A D R F L L V F K P I W C Q N F R G A G L A W I A C A V A W G L A L L L T I P S F L Y R V V R E E Y F P P K V L C G V D Y S H D K R R E R A V A I V R L V L G F L W P L L T L T I C Y T F I L L R T W S R R A T R S T K T L K V V V A V V A S F F I F W L P Y Q V T G I M M S F L E P S S P T F L L L K K L D S L C V S F A Y I N C C I N P I I Y V V A G Q G F Q G R L R K S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	5O9H	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	-	NDT9513727	-	2.7	2018-01-10	doi.org/10.1038/nature25025
	6C1Q	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	PMX53	NDT9513727	-	2.9	2018-05-30	doi.org/10.1038/s41594-018-0067-z
	6C1R	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	PMX53	Avacopan; Na	-	2.2	2018-05-30	doi.org/10.1038/s41594-018-0067-z
	7Y64	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Gi1/β1/γ2	2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y64 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y65	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a (C-terminal peptide)	-	Gi1/β1/γ2	3.2	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y65 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a (C-terminal peptide)	-		3.2	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y66	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	BM213	-	Gi1/β1/γ2	2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y66 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	BM213	-		2.9	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y67	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C089 peptide	-	Gi1/β1/γ2	2.8	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	7Y67 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C089 peptide	-		2.8	2023-03-01	doi.org/10.1038/s41422-023-00779-2
	8HK5	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Gi1/β1/γ2	3	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK5 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		3	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HPT	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a (C-terminal peptide)	-	Go/β1/γ2	3.39	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HPT (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a (C-terminal peptide)	-		3.39	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HQC	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-	Go/β1/γ2	3.89	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8HQC (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-		3.89	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8IA2	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Go/β1/γ2	3.21	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8IA2 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		3.21	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8JZZ	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-des-Arg	-	Go/β1/γ2	3.31	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8JZZ (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-des-Arg	-		3.31	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	9KWG	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-	Go/β1/γ2	3.15	2025-11-26	10.1101/2025.05.26.656101
	9KWG (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a	-		3.15	2025-11-26	10.1101/2025.05.26.656101
	9KWX	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-	Go/β1/γ2	3.13	2025-11-26	10.1101/2025.05.26.656101
	9KWX (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-		3.13	2025-11-26	10.1101/2025.05.26.656101
	9KX6	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-	Go/β1/γ2	3.11	2025-11-26	10.1101/2025.05.26.656101
	9KX6 (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	C5a-des-Arg	-		3.11	2025-11-26	10.1101/2025.05.26.656101
	9KXS	A	Peptide	Complement Peptide	C5a₁	Mus musculus	EP67	-	Go/β1/γ2	3.31	2025-11-26	10.1101/2025.05.26.656101
	9KXS (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Mus musculus	EP67	-		3.31	2025-11-26	10.1101/2025.05.26.656101
	9UMR	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-pep	-	Go/β1/γ2	3.15	2025-11-26	10.1101/2025.05.26.656101
	9UMR (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a-pep	-		3.15	2025-11-26	10.1101/2025.05.26.656101
	9UMX	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP54	-	Go/β1/γ2	3.2	2025-11-26	10.1101/2025.05.26.656101
	9UMX (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP54	-		3.2	2025-11-26	10.1101/2025.05.26.656101
	8JZP	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-	Go/β1/γ2	3.54	2025-01-15	To be published
	8JZP (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	C5a	-		3.54	2025-01-15	To be published
	9KUG	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP67	-	Go/β1/γ2	3.07	2025-11-26	10.1101/2025.05.26.656101
	9KUG (No Gprot)	A	Peptide	Complement Peptide	C5a₁	Homo sapiens	EP67	-		3.07	2025-11-26	10.1101/2025.05.26.656101

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9UMX_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.