| Color | ConSurf Grade |
| No Conservation data available | |
| 1 | |
| 2 | |
| 3 | |
| 4 | |
| 5 | |
| 6 | |
| 7 | |
| 8 | |
| 9 |
Index: link id, click on each number to highlight the corresponding link in the 3D visualization.
Node1 Node2: the two nodes of the corresponding link.
Int. Strength: the interaction strength between the two nodes.
Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".
Community: the id of the community the link belong to, otherwise 0.
ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.
| Index | Node1 | Node2 | Int. Strength | Hub1? | Hub2? | Community | ConSurf1 | ConSurf2 |
|---|---|---|---|---|---|---|---|---|
| 1 | L:L:?1 | L:L:C2 | 12.1 | Yes | No | 1 | 0 | 0 |
| 2 | L:L:?1 | L:L:C7 | 5.38 | Yes | Yes | 1 | 0 | 0 |
| 3 | L:L:?1 | R:R:Q187 | 6.77 | Yes | Yes | 1 | 0 | 2 |
| 4 | L:L:?1 | R:R:P286 | 8.35 | Yes | No | 1 | 0 | 2 |
| 5 | L:L:C2 | L:L:C7 | 7.28 | No | Yes | 1 | 0 | 0 |
| 6 | L:L:C2 | R:R:F294 | 13.97 | No | Yes | 1 | 0 | 4 |
| 7 | L:L:?4 | L:L:F3 | 5.8 | Yes | Yes | 1 | 0 | 0 |
| 8 | L:L:F3 | R:R:Y205 | 14.44 | Yes | No | 0 | 0 | 4 |
| 9 | L:L:F3 | R:R:F208 | 7.5 | Yes | Yes | 1 | 0 | 7 |
| 10 | L:L:?4 | L:L:K5 | 22.39 | Yes | Yes | 0 | 0 | 0 |
| 11 | L:L:?4 | R:R:Q126 | 6.34 | Yes | Yes | 1 | 0 | 7 |
| 12 | L:L:?4 | R:R:F127 | 2.9 | Yes | Yes | 1 | 0 | 6 |
| 13 | L:L:?4 | R:R:I177 | 4.53 | Yes | No | 1 | 0 | 3 |
| 14 | L:L:?4 | R:R:F208 | 12.57 | Yes | Yes | 1 | 0 | 7 |
| 15 | L:L:?4 | R:R:T212 | 8.19 | Yes | Yes | 1 | 0 | 4 |
| 16 | L:L:?4 | R:R:F272 | 3.87 | Yes | Yes | 1 | 0 | 6 |
| 17 | L:L:?4 | R:R:N276 | 7.63 | Yes | Yes | 1 | 0 | 6 |
| 18 | L:L:K5 | R:R:L99 | 4.23 | Yes | No | 0 | 0 | 6 |
| 19 | L:L:K5 | R:R:V298 | 3.04 | Yes | No | 0 | 0 | 6 |
| 20 | L:L:K5 | R:R:Y302 | 7.17 | Yes | Yes | 0 | 0 | 7 |
| 21 | L:L:T6 | R:R:Q102 | 9.92 | No | Yes | 0 | 0 | 5 |
| 22 | L:L:C7 | R:R:Q187 | 3.05 | Yes | Yes | 1 | 0 | 2 |
| 23 | L:L:C7 | R:R:F294 | 5.59 | Yes | Yes | 1 | 0 | 4 |
| 24 | R:R:N43 | R:R:S42 | 7.45 | No | No | 0 | 3 | 4 |
| 25 | R:R:K291 | R:R:N43 | 5.6 | Yes | No | 0 | 3 | 3 |
| 26 | R:R:F296 | R:R:L46 | 12.18 | No | No | 0 | 5 | 5 |
| 27 | R:R:A104 | R:R:T47 | 5.03 | No | No | 0 | 5 | 5 |
| 28 | R:R:F48 | R:R:F51 | 3.22 | No | No | 0 | 6 | 5 |
| 29 | R:R:I49 | R:R:V299 | 3.07 | No | No | 0 | 5 | 5 |
| 30 | R:R:L96 | R:R:Y50 | 11.72 | Yes | Yes | 0 | 7 | 7 |
| 31 | R:R:A100 | R:R:Y50 | 5.34 | No | Yes | 0 | 6 | 7 |
| 32 | R:R:D295 | R:R:Y50 | 3.45 | No | Yes | 0 | 2 | 7 |
| 33 | R:R:V298 | R:R:Y50 | 3.79 | No | Yes | 0 | 6 | 7 |
| 34 | R:R:V299 | R:R:Y50 | 10.09 | No | Yes | 0 | 5 | 7 |
| 35 | R:R:C54 | R:R:F51 | 4.19 | Yes | No | 0 | 6 | 5 |
| 36 | R:R:L96 | R:R:V53 | 2.98 | Yes | No | 0 | 7 | 7 |
| 37 | R:R:V299 | R:R:V53 | 3.21 | No | No | 0 | 5 | 7 |
| 38 | R:R:C54 | R:R:M93 | 8.1 | Yes | No | 0 | 6 | 6 |
| 39 | R:R:C54 | R:R:L96 | 3.17 | Yes | Yes | 0 | 6 | 7 |
| 40 | R:R:C54 | R:R:P97 | 5.65 | Yes | No | 0 | 6 | 8 |
| 41 | R:R:C306 | R:R:I56 | 8.18 | No | No | 0 | 8 | 4 |
| 42 | R:R:C306 | R:R:G57 | 3.92 | No | No | 0 | 8 | 8 |
| 43 | R:R:E90 | R:R:L58 | 6.63 | No | No | 0 | 7 | 6 |
| 44 | R:R:L58 | R:R:M93 | 5.65 | No | No | 0 | 6 | 6 |
| 45 | R:R:G60 | R:R:L63 | 3.42 | No | No | 0 | 8 | 6 |
| 46 | R:R:D89 | R:R:N61 | 17.5 | Yes | No | 1 | 9 | 9 |
| 47 | R:R:N61 | R:R:P309 | 13.03 | No | No | 1 | 9 | 9 |
| 48 | R:R:A86 | R:R:V64 | 3.39 | No | No | 0 | 9 | 9 |
| 49 | R:R:A313 | R:R:V64 | 5.09 | No | No | 0 | 7 | 9 |
| 50 | R:R:A86 | R:R:I65 | 3.25 | No | No | 0 | 9 | 7 |
| 51 | R:R:E90 | R:R:I65 | 6.83 | No | No | 0 | 7 | 7 |
| 52 | R:R:F319 | R:R:V67 | 20.97 | Yes | No | 0 | 8 | 7 |
| 53 | R:R:I68 | R:R:N79 | 4.25 | No | Yes | 0 | 7 | 8 |
| 54 | R:R:I68 | R:R:L83 | 7.14 | No | No | 0 | 7 | 6 |
| 55 | R:R:L69 | R:R:M74 | 4.24 | No | No | 0 | 3 | 7 |
| 56 | R:R:R70 | R:R:Y71 | 4.12 | No | No | 0 | 4 | 6 |
| 57 | R:R:V326 | R:R:Y71 | 17.66 | No | No | 0 | 5 | 6 |
| 58 | R:R:K73 | R:R:T76 | 12.01 | No | No | 2 | 5 | 7 |
| 59 | R:R:K73 | R:R:N79 | 8.39 | No | Yes | 2 | 5 | 8 |
| 60 | R:R:K75 | R:R:M74 | 4.32 | No | No | 0 | 7 | 7 |
| 61 | R:R:I80 | R:R:K75 | 5.82 | No | No | 0 | 5 | 7 |
| 62 | R:R:T76 | R:R:T78 | 3.14 | No | No | 2 | 7 | 8 |
| 63 | R:R:N79 | R:R:T76 | 4.39 | Yes | No | 2 | 8 | 7 |
| 64 | R:R:I77 | R:R:R154 | 18.79 | No | Yes | 0 | 4 | 5 |
| 65 | R:R:I77 | R:R:P156 | 6.77 | No | No | 0 | 4 | 3 |
| 66 | R:R:N79 | R:R:T78 | 2.92 | Yes | No | 2 | 8 | 8 |
| 67 | R:R:D139 | R:R:T78 | 2.89 | No | No | 0 | 8 | 8 |
| 68 | R:R:I82 | R:R:N79 | 4.25 | No | Yes | 0 | 8 | 8 |
| 69 | R:R:A159 | R:R:I80 | 3.25 | No | No | 0 | 7 | 5 |
| 70 | R:R:D139 | R:R:Y81 | 8.05 | No | No | 0 | 8 | 7 |
| 71 | R:R:A159 | R:R:Y81 | 5.34 | No | No | 0 | 7 | 7 |
| 72 | R:R:I162 | R:R:Y81 | 8.46 | No | No | 0 | 5 | 7 |
| 73 | R:R:I82 | R:R:M136 | 7.29 | No | No | 0 | 8 | 9 |
| 74 | R:R:C132 | R:R:N84 | 3.15 | No | No | 0 | 8 | 9 |
| 75 | R:R:N84 | R:R:T163 | 13.16 | No | No | 0 | 9 | 7 |
| 76 | R:R:N84 | R:R:W167 | 6.78 | No | No | 0 | 9 | 9 |
| 77 | R:R:C132 | R:R:L85 | 7.94 | No | No | 0 | 8 | 9 |
| 78 | R:R:L133 | R:R:L85 | 4.15 | No | No | 1 | 9 | 9 |
| 79 | R:R:L85 | R:R:N308 | 8.24 | No | Yes | 1 | 9 | 9 |
| 80 | R:R:A88 | R:R:N125 | 3.13 | No | No | 0 | 8 | 7 |
| 81 | R:R:D89 | R:R:S305 | 11.78 | Yes | No | 0 | 9 | 8 |
| 82 | R:R:D89 | R:R:N308 | 4.04 | Yes | Yes | 1 | 9 | 9 |
| 83 | R:R:D89 | R:R:P309 | 4.83 | Yes | No | 1 | 9 | 9 |
| 84 | R:R:L91 | R:R:N125 | 12.36 | No | No | 0 | 7 | 7 |
| 85 | R:R:D122 | R:R:F92 | 11.94 | No | Yes | 1 | 6 | 6 |
| 86 | R:R:F92 | R:R:N125 | 6.04 | Yes | No | 0 | 6 | 7 |
| 87 | R:R:F92 | R:R:Q126 | 10.54 | Yes | Yes | 1 | 6 | 7 |
| 88 | R:R:F92 | R:R:Y302 | 24.76 | Yes | Yes | 1 | 6 | 7 |
| 89 | R:R:D122 | R:R:G95 | 5.03 | No | No | 0 | 6 | 6 |
| 90 | R:R:L96 | R:R:Y302 | 16.41 | Yes | Yes | 0 | 7 | 7 |
| 91 | R:R:F98 | R:R:W108 | 4.01 | No | Yes | 0 | 5 | 8 |
| 92 | R:R:F98 | R:R:V118 | 15.73 | No | No | 0 | 5 | 5 |
| 93 | R:R:Q102 | R:R:V103 | 4.3 | Yes | Yes | 0 | 5 | 4 |
| 94 | R:R:Q102 | R:R:W108 | 9.86 | Yes | Yes | 0 | 5 | 8 |
| 95 | R:R:K291 | R:R:V103 | 6.07 | Yes | Yes | 5 | 3 | 4 |
| 96 | R:R:D295 | R:R:V103 | 11.69 | No | Yes | 5 | 2 | 4 |
| 97 | R:R:K291 | R:R:V106 | 4.55 | Yes | No | 0 | 3 | 4 |
| 98 | R:R:P109 | R:R:W108 | 25.67 | No | Yes | 0 | 4 | 8 |
| 99 | R:R:G111 | R:R:W108 | 4.22 | No | Yes | 3 | 7 | 8 |
| 100 | R:R:C115 | R:R:W108 | 10.45 | No | Yes | 3 | 9 | 8 |
| 101 | R:R:C193 | R:R:W108 | 16.98 | No | Yes | 3 | 9 | 8 |
| 102 | R:R:F110 | R:R:K112 | 9.93 | No | No | 0 | 6 | 3 |
| 103 | R:R:F110 | R:R:I114 | 3.77 | No | No | 0 | 6 | 6 |
| 104 | R:R:C115 | R:R:G111 | 3.92 | No | No | 3 | 9 | 7 |
| 105 | R:R:C115 | R:R:C193 | 3.64 | No | No | 3 | 9 | 9 |
| 106 | R:R:A181 | R:R:R116 | 5.53 | No | No | 0 | 4 | 6 |
| 107 | R:R:I177 | R:R:M119 | 2.92 | No | No | 0 | 3 | 5 |
| 108 | R:R:D122 | R:R:Y302 | 5.75 | No | Yes | 1 | 6 | 7 |
| 109 | R:R:I124 | R:R:L171 | 4.28 | No | No | 0 | 5 | 3 |
| 110 | R:R:I124 | R:R:I174 | 5.89 | No | No | 0 | 5 | 7 |
| 111 | R:R:F127 | R:R:Q126 | 9.37 | Yes | Yes | 1 | 6 | 7 |
| 112 | R:R:Q126 | R:R:W269 | 9.86 | Yes | Yes | 1 | 7 | 8 |
| 113 | R:R:F127 | R:R:T212 | 5.19 | Yes | Yes | 1 | 6 | 4 |
| 114 | R:R:F127 | R:R:G216 | 4.52 | Yes | No | 0 | 6 | 6 |
| 115 | R:R:T128 | R:R:V166 | 4.76 | No | No | 0 | 7 | 6 |
| 116 | R:R:T128 | R:R:W167 | 12.13 | No | No | 0 | 7 | 9 |
| 117 | R:R:S170 | R:R:T128 | 7.99 | No | No | 0 | 7 | 7 |
| 118 | R:R:S129 | R:R:S305 | 3.26 | No | No | 0 | 9 | 8 |
| 119 | R:R:C132 | R:R:V135 | 3.42 | No | No | 0 | 8 | 7 |
| 120 | R:R:L133 | R:R:N308 | 10.98 | No | Yes | 1 | 9 | 9 |
| 121 | R:R:L133 | R:R:Y312 | 5.86 | No | Yes | 1 | 9 | 9 |
| 122 | R:R:P220 | R:R:T134 | 3.5 | No | No | 0 | 9 | 7 |
| 123 | R:R:I223 | R:R:T134 | 4.56 | No | No | 0 | 6 | 7 |
| 124 | R:R:M136 | R:R:Y312 | 5.99 | No | Yes | 0 | 9 | 9 |
| 125 | R:R:I224 | R:R:S137 | 7.74 | No | No | 0 | 7 | 9 |
| 126 | R:R:C227 | R:R:S137 | 3.44 | No | No | 0 | 7 | 9 |
| 127 | R:R:S137 | R:R:Y228 | 8.9 | No | Yes | 0 | 9 | 9 |
| 128 | R:R:I138 | R:R:I223 | 2.94 | No | No | 0 | 6 | 6 |
| 129 | R:R:D139 | R:R:R154 | 9.53 | No | Yes | 0 | 8 | 5 |
| 130 | R:R:R140 | R:R:Y228 | 12.35 | No | Yes | 1 | 9 | 9 |
| 131 | R:R:R140 | R:R:Y312 | 9.26 | No | Yes | 1 | 9 | 9 |
| 132 | R:R:L142 | R:R:Y141 | 3.52 | No | Yes | 0 | 4 | 8 |
| 133 | R:R:V145 | R:R:Y141 | 11.36 | No | Yes | 6 | 7 | 8 |
| 134 | R:R:H146 | R:R:Y141 | 7.62 | Yes | Yes | 6 | 5 | 8 |
| 135 | R:R:C227 | R:R:Y141 | 8.06 | No | Yes | 0 | 7 | 8 |
| 136 | R:R:F230 | R:R:Y141 | 6.19 | No | Yes | 0 | 4 | 8 |
| 137 | R:R:A143 | R:R:R154 | 5.53 | No | Yes | 0 | 8 | 5 |
| 138 | R:R:I231 | R:R:V144 | 6.14 | No | No | 0 | 9 | 8 |
| 139 | R:R:H146 | R:R:V145 | 5.54 | Yes | No | 6 | 5 | 7 |
| 140 | R:R:K234 | R:R:V145 | 4.55 | No | No | 0 | 5 | 7 |
| 141 | R:R:I148 | R:R:K149 | 4.36 | No | No | 0 | 5 | 4 |
| 142 | R:R:R154 | R:R:S150 | 5.27 | Yes | No | 0 | 5 | 5 |
| 143 | R:R:R155 | R:R:R157 | 6.4 | No | No | 0 | 6 | 4 |
| 144 | R:R:K160 | R:R:R157 | 7.43 | No | No | 0 | 1 | 4 |
| 145 | R:R:M161 | R:R:T158 | 4.52 | No | No | 0 | 1 | 5 |
| 146 | R:R:K160 | R:R:M164 | 4.32 | No | No | 0 | 1 | 4 |
| 147 | R:R:V173 | R:R:Y211 | 6.31 | No | No | 1 | 4 | 4 |
| 148 | R:R:L215 | R:R:V173 | 2.98 | No | No | 1 | 4 | 4 |
| 149 | R:R:L175 | R:R:P176 | 4.93 | No | No | 0 | 4 | 8 |
| 150 | R:R:F208 | R:R:I177 | 5.02 | Yes | No | 1 | 7 | 3 |
| 151 | R:R:I179 | R:R:Y180 | 8.46 | No | No | 0 | 4 | 4 |
| 152 | R:R:I195 | R:R:Y180 | 3.63 | No | No | 0 | 5 | 4 |
| 153 | R:R:P198 | R:R:Y180 | 11.13 | No | No | 0 | 5 | 4 |
| 154 | R:R:G182 | R:R:N196 | 6.79 | No | No | 0 | 5 | 3 |
| 155 | R:R:L183 | R:R:S191 | 9.01 | No | No | 0 | 4 | 5 |
| 156 | R:R:N196 | R:R:R184 | 12.05 | No | No | 0 | 3 | 2 |
| 157 | R:R:R184 | R:R:W197 | 13 | No | No | 0 | 2 | 5 |
| 158 | R:R:S185 | R:R:S191 | 6.52 | No | No | 0 | 2 | 5 |
| 159 | R:R:N186 | R:R:Q187 | 6.6 | No | Yes | 0 | 1 | 2 |
| 160 | R:R:Q187 | R:R:W188 | 16.43 | Yes | No | 0 | 2 | 2 |
| 161 | R:R:P286 | R:R:Q187 | 3.16 | No | Yes | 1 | 2 | 2 |
| 162 | R:R:I195 | R:R:T194 | 3.04 | No | No | 0 | 5 | 4 |
| 163 | R:R:W197 | R:R:Y205 | 8.68 | No | No | 0 | 5 | 4 |
| 164 | R:R:T206 | R:R:V280 | 4.76 | No | No | 0 | 3 | 4 |
| 165 | R:R:G207 | R:R:I210 | 3.53 | No | No | 0 | 4 | 5 |
| 166 | R:R:F208 | R:R:I209 | 3.77 | Yes | Yes | 1 | 7 | 5 |
| 167 | R:R:F208 | R:R:T212 | 5.19 | Yes | Yes | 1 | 7 | 4 |
| 168 | R:R:I209 | R:R:T212 | 3.04 | Yes | Yes | 1 | 5 | 4 |
| 169 | R:R:I209 | R:R:N276 | 11.33 | Yes | Yes | 1 | 5 | 6 |
| 170 | R:R:L215 | R:R:Y211 | 3.52 | No | No | 1 | 4 | 4 |
| 171 | R:R:T212 | R:R:Y273 | 8.74 | Yes | No | 0 | 4 | 7 |
| 172 | R:R:F213 | R:R:L218 | 9.74 | No | No | 0 | 5 | 4 |
| 173 | R:R:I214 | R:R:L215 | 9.99 | No | No | 0 | 4 | 4 |
| 174 | R:R:I214 | R:R:V219 | 4.61 | No | No | 0 | 4 | 5 |
| 175 | R:R:F217 | R:R:I266 | 6.28 | Yes | No | 1 | 8 | 6 |
| 176 | R:R:F217 | R:R:L270 | 4.87 | Yes | Yes | 1 | 8 | 5 |
| 177 | R:R:F217 | R:R:Y273 | 6.19 | Yes | No | 0 | 8 | 7 |
| 178 | R:R:P220 | R:R:V219 | 3.53 | No | No | 0 | 9 | 5 |
| 179 | R:R:C225 | R:R:L221 | 3.17 | No | Yes | 1 | 5 | 6 |
| 180 | R:R:L221 | R:R:V262 | 2.98 | Yes | No | 1 | 6 | 7 |
| 181 | R:R:F265 | R:R:L221 | 7.31 | No | Yes | 0 | 9 | 6 |
| 182 | R:R:I223 | R:R:T222 | 3.04 | No | No | 0 | 6 | 4 |
| 183 | R:R:C225 | R:R:V262 | 5.12 | No | No | 1 | 5 | 7 |
| 184 | R:R:V258 | R:R:Y228 | 6.31 | Yes | Yes | 1 | 8 | 9 |
| 185 | R:R:Y228 | R:R:Y312 | 4.96 | Yes | Yes | 1 | 9 | 9 |
| 186 | R:R:I232 | R:R:T255 | 7.6 | No | No | 1 | 5 | 7 |
| 187 | R:R:I232 | R:R:V258 | 6.14 | No | Yes | 1 | 5 | 8 |
| 188 | R:R:K234 | R:R:S237 | 7.65 | No | No | 0 | 5 | 5 |
| 189 | R:R:K236 | R:R:S237 | 3.06 | Yes | No | 0 | 4 | 5 |
| 190 | R:R:I240 | R:R:K236 | 8.72 | No | Yes | 4 | 3 | 4 |
| 191 | R:R:E251 | R:R:K236 | 6.75 | Yes | Yes | 4 | 6 | 4 |
| 192 | R:R:G239 | R:R:S238 | 3.71 | No | No | 0 | 5 | 5 |
| 193 | R:R:I240 | R:R:K248 | 15.99 | No | No | 4 | 3 | 3 |
| 194 | R:R:E251 | R:R:I240 | 5.47 | Yes | No | 4 | 6 | 3 |
| 195 | R:R:R241 | R:R:V242 | 3.92 | No | No | 0 | 1 | 3 |
| 196 | R:R:G243 | R:R:S244 | 3.71 | No | No | 0 | 1 | 3 |
| 197 | R:R:K249 | R:R:R247 | 9.9 | No | No | 0 | 4 | 4 |
| 198 | R:R:E251 | R:R:K248 | 5.4 | Yes | No | 4 | 6 | 3 |
| 199 | R:R:K249 | R:R:K253 | 10.06 | No | No | 0 | 4 | 7 |
| 200 | R:R:E251 | R:R:S250 | 4.31 | Yes | No | 0 | 6 | 5 |
| 201 | R:R:T255 | R:R:V258 | 3.17 | No | Yes | 1 | 7 | 8 |
| 202 | R:R:L315 | R:R:M257 | 4.24 | No | No | 0 | 6 | 8 |
| 203 | R:R:L311 | R:R:V261 | 4.47 | No | No | 0 | 8 | 8 |
| 204 | R:R:L311 | R:R:V264 | 2.98 | No | No | 0 | 8 | 7 |
| 205 | R:R:I266 | R:R:L270 | 5.71 | No | Yes | 1 | 6 | 5 |
| 206 | R:R:C268 | R:R:W269 | 9.14 | No | Yes | 1 | 8 | 8 |
| 207 | R:R:C268 | R:R:N304 | 4.72 | No | No | 1 | 8 | 9 |
| 208 | R:R:F272 | R:R:W269 | 3.01 | Yes | Yes | 1 | 6 | 8 |
| 209 | R:R:W269 | R:R:Y273 | 3.86 | Yes | No | 0 | 8 | 7 |
| 210 | R:R:T301 | R:R:W269 | 19.41 | No | Yes | 1 | 7 | 8 |
| 211 | R:R:N304 | R:R:W269 | 9.04 | No | Yes | 1 | 9 | 8 |
| 212 | R:R:L270 | R:R:P271 | 3.28 | Yes | No | 1 | 5 | 9 |
| 213 | R:R:I274 | R:R:L270 | 5.71 | No | Yes | 0 | 5 | 5 |
| 214 | R:R:P271 | R:R:V297 | 3.53 | No | Yes | 1 | 9 | 7 |
| 215 | R:R:L300 | R:R:P271 | 3.28 | No | No | 1 | 7 | 9 |
| 216 | R:R:F272 | R:R:N276 | 3.62 | Yes | Yes | 1 | 6 | 6 |
| 217 | R:R:F272 | R:R:V297 | 3.93 | Yes | Yes | 1 | 6 | 7 |
| 218 | R:R:F272 | R:R:T301 | 5.19 | Yes | No | 1 | 6 | 7 |
| 219 | R:R:F275 | R:R:M293 | 8.71 | No | No | 0 | 4 | 4 |
| 220 | R:R:F275 | R:R:F294 | 6.43 | No | Yes | 0 | 4 | 4 |
| 221 | R:R:F275 | R:R:V297 | 6.55 | No | Yes | 0 | 4 | 7 |
| 222 | R:R:F294 | R:R:N276 | 8.46 | Yes | Yes | 1 | 4 | 6 |
| 223 | R:R:M282 | R:R:S278 | 3.07 | No | No | 0 | 3 | 4 |
| 224 | R:R:M282 | R:R:S281 | 3.07 | No | No | 0 | 3 | 4 |
| 225 | R:R:P288 | R:R:T287 | 5.25 | No | No | 0 | 3 | 1 |
| 226 | R:R:L290 | R:R:T287 | 8.84 | No | No | 0 | 4 | 1 |
| 227 | R:R:D295 | R:R:K291 | 9.68 | No | Yes | 5 | 2 | 3 |
| 228 | R:R:L300 | R:R:V297 | 2.98 | No | Yes | 1 | 7 | 7 |
| 229 | R:R:T301 | R:R:Y302 | 3.75 | No | Yes | 1 | 7 | 7 |
| 230 | R:R:N304 | R:R:N308 | 9.54 | No | Yes | 1 | 9 | 9 |
| 231 | R:R:F314 | R:R:I310 | 7.54 | No | No | 0 | 7 | 6 |
| 232 | R:R:L311 | R:R:Y312 | 4.69 | No | Yes | 0 | 8 | 9 |
| 233 | R:R:F314 | R:R:F323 | 3.22 | No | No | 0 | 7 | 6 |
| 234 | R:R:N318 | R:R:S322 | 10.43 | No | No | 0 | 5 | 5 |
| 235 | R:R:F319 | R:R:F323 | 9.65 | Yes | No | 0 | 8 | 6 |
| 236 | R:R:K320 | R:R:K321 | 7.18 | No | No | 0 | 8 | 5 |
| 237 | R:R:K321 | R:R:Q324 | 6.78 | No | No | 0 | 5 | 4 |
| 238 | R:R:I266 | R:R:L221 | 2.85 | No | Yes | 1 | 6 | 6 |
| 239 | R:R:E251 | R:R:V235 | 2.85 | Yes | No | 0 | 6 | 8 |
| 240 | R:R:I284 | R:R:L290 | 2.85 | No | No | 0 | 1 | 4 |
| 241 | R:R:A313 | R:R:F319 | 2.77 | No | Yes | 0 | 7 | 8 |
| 242 | R:R:F319 | R:R:S322 | 2.64 | Yes | No | 0 | 8 | 5 |
| 243 | L:L:F3 | R:R:V280 | 2.62 | Yes | No | 0 | 0 | 4 |
| 244 | R:R:F127 | R:R:V173 | 2.62 | Yes | No | 1 | 6 | 4 |
| 245 | R:R:F131 | R:R:V166 | 2.62 | No | No | 0 | 6 | 6 |
| 246 | R:R:H146 | R:R:K149 | 2.62 | Yes | No | 0 | 5 | 4 |
| 247 | L:L:?1 | R:R:S279 | 2.54 | Yes | No | 0 | 0 | 4 |
| 248 | L:L:F3 | R:R:I195 | 2.51 | Yes | No | 0 | 0 | 5 |
| 249 | R:R:F265 | R:R:I130 | 2.51 | No | No | 0 | 9 | 8 |
| 250 | R:R:M161 | R:R:R157 | 2.48 | No | No | 0 | 1 | 4 |
| 251 | R:R:K236 | R:R:R241 | 2.48 | Yes | No | 0 | 4 | 1 |
| 252 | R:R:F319 | R:R:L63 | 2.44 | Yes | No | 0 | 8 | 6 |
| 253 | L:L:?1 | R:R:I284 | 2.42 | Yes | No | 0 | 0 | 1 |
| 254 | R:R:I231 | R:R:Y228 | 2.42 | No | Yes | 0 | 9 | 9 |
| 255 | R:R:I87 | R:R:W167 | 2.35 | No | No | 0 | 7 | 9 |
| 256 | R:R:H107 | R:R:R190 | 2.26 | No | No | 0 | 4 | 1 |
| 257 | R:R:F213 | R:R:F217 | 2.14 | No | Yes | 0 | 5 | 8 |
| 258 | R:R:F110 | R:R:W108 | 2 | No | Yes | 0 | 6 | 8 |
| 259 | R:R:G189 | R:R:S185 | 1.86 | No | No | 0 | 6 | 2 |
| 260 | R:R:G239 | R:R:S244 | 1.86 | No | No | 0 | 5 | 3 |
| 261 | R:R:G243 | R:R:V242 | 1.84 | No | No | 0 | 1 | 3 |
| 262 | R:R:G207 | R:R:T206 | 1.82 | No | No | 0 | 4 | 3 |
| 263 | R:R:P286 | R:R:S285 | 1.78 | No | No | 0 | 2 | 2 |
| 264 | R:R:G123 | R:R:I174 | 1.76 | No | No | 0 | 4 | 7 |
| 265 | R:R:G57 | R:R:M93 | 1.75 | No | No | 0 | 8 | 6 |
| 266 | R:R:G292 | R:R:L46 | 1.71 | No | No | 0 | 1 | 5 |
| 267 | R:R:G111 | R:R:L183 | 1.71 | No | No | 0 | 7 | 4 |
| 268 | R:R:A151 | R:R:S150 | 1.71 | No | No | 0 | 4 | 5 |
| 269 | R:R:A307 | R:R:V264 | 1.7 | No | No | 0 | 6 | 7 |
| 270 | R:R:M101 | R:R:P109 | 1.68 | No | No | 0 | 5 | 4 |
| 271 | R:R:A289 | R:R:T287 | 1.68 | No | No | 0 | 1 | 1 |
| 272 | R:R:L94 | R:R:P97 | 1.64 | No | No | 0 | 5 | 8 |
| 273 | R:R:G123 | R:R:Q126 | 1.64 | No | Yes | 0 | 4 | 7 |
| 274 | R:R:A72 | R:R:M74 | 1.61 | No | No | 0 | 5 | 7 |
| 275 | R:R:V52 | R:R:V53 | 1.6 | No | No | 0 | 5 | 7 |
| 276 | R:R:T41 | R:R:V45 | 1.59 | No | No | 0 | 4 | 5 |
| 277 | R:R:T47 | R:R:V103 | 1.59 | No | Yes | 0 | 5 | 4 |
| 278 | R:R:T120 | R:R:V117 | 1.59 | No | No | 0 | 6 | 5 |
| 279 | R:R:A104 | R:R:L105 | 1.58 | No | No | 0 | 5 | 5 |
| 280 | R:R:I82 | R:R:S316 | 1.55 | No | No | 0 | 8 | 8 |
| 281 | R:R:I55 | R:R:V52 | 1.54 | No | No | 0 | 4 | 5 |
| 282 | R:R:I114 | R:R:V117 | 1.54 | No | No | 0 | 6 | 5 |
| 283 | R:R:I124 | R:R:V121 | 1.54 | No | No | 0 | 5 | 5 |
| 284 | R:R:I209 | R:R:V277 | 1.54 | Yes | No | 0 | 5 | 5 |
| 285 | R:R:I260 | R:R:V264 | 1.54 | No | No | 0 | 6 | 7 |
| 286 | R:R:H107 | R:R:P109 | 1.53 | No | No | 0 | 4 | 4 |
| 287 | R:R:H146 | R:R:P147 | 1.53 | Yes | No | 0 | 5 | 8 |
| 288 | R:R:I65 | R:R:T62 | 1.52 | No | No | 0 | 7 | 5 |
| 289 | R:R:M257 | R:R:V258 | 1.52 | No | Yes | 0 | 8 | 8 |
| 290 | R:R:M178 | R:R:T120 | 1.51 | No | No | 0 | 5 | 6 |
| 291 | R:R:K160 | R:R:T163 | 1.5 | No | No | 0 | 1 | 7 |
| 292 | R:R:L46 | R:R:V45 | 1.49 | No | No | 0 | 5 | 5 |
| 293 | R:R:N325 | R:R:V326 | 1.48 | No | No | 0 | 4 | 5 |
| 294 | R:R:Q102 | R:R:S192 | 1.44 | Yes | No | 0 | 5 | 4 |
| 295 | R:R:K246 | R:R:K248 | 1.44 | No | No | 0 | 3 | 3 |
| 296 | R:R:L175 | R:R:M178 | 1.41 | No | No | 0 | 4 | 5 |
| 297 | R:R:P198 | R:R:W204 | 1.35 | No | No | 0 | 5 | 3 |
| 298 | R:R:E251 | R:R:K252 | 1.35 | Yes | No | 0 | 6 | 5 |
| 299 | R:R:D317 | R:R:N318 | 1.35 | No | No | 0 | 5 | 5 |
| 300 | R:R:R247 | R:R:S245 | 1.32 | No | No | 0 | 4 | 2 |
| 301 | R:R:R247 | R:R:S250 | 1.32 | No | No | 0 | 4 | 5 |
| 302 | R:R:F296 | R:R:I49 | 1.26 | No | No | 0 | 5 | 5 |
| 303 | R:R:F230 | R:R:I233 | 1.26 | No | No | 0 | 4 | 3 |
| 304 | R:R:T62 | R:R:Y66 | 1.25 | No | No | 0 | 5 | 3 |
| Color | ConSurf Grade |
| No Conservation data available | |
| 1 | |
| 2 | |
| 3 | |
| 4 | |
| 5 | |
| 6 | |
| 7 | |
| 8 | |
| 9 |
Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.
Hub: the hub being considered.
Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.
Num Of Links: the number of links of the corresponding hub.
Community: the id of the community the link belong to, otherwise 0.
ConSurf: this column reports the ConSurf conservation grades of each hub.
| Index | Hub | Avg Int. Strength | Num Of Links | Community | ConSurf |
|---|---|---|---|---|---|
| 1 | L:L:?1 | 6.26 | 6 | 1 | 0 |
| 2 | L:L:F3 | 6.574 | 5 | 1 | 0 |
| 3 | L:L:?4 | 8.24667 | 9 | 1 | 0 |
| 4 | L:L:K5 | 9.2075 | 4 | 0 | 0 |
| 5 | L:L:C7 | 5.325 | 4 | 1 | 0 |
| 6 | R:R:Y50 | 6.878 | 5 | 0 | 7 |
| 7 | R:R:C54 | 5.2775 | 4 | 0 | 6 |
| 8 | R:R:N79 | 4.84 | 5 | 2 | 8 |
| 9 | R:R:D89 | 9.5375 | 4 | 1 | 9 |
| 10 | R:R:F92 | 13.32 | 4 | 1 | 6 |
| 11 | R:R:L96 | 8.57 | 4 | 0 | 7 |
| 12 | R:R:Q102 | 6.38 | 4 | 0 | 5 |
| 13 | R:R:V103 | 5.9125 | 4 | 5 | 4 |
| 14 | R:R:W108 | 10.4557 | 7 | 3 | 8 |
| 15 | R:R:Q126 | 7.55 | 5 | 1 | 7 |
| 16 | R:R:F127 | 4.92 | 5 | 1 | 6 |
| 17 | R:R:Y141 | 7.35 | 5 | 6 | 8 |
| 18 | R:R:H146 | 4.3275 | 4 | 6 | 5 |
| 19 | R:R:R154 | 9.78 | 4 | 0 | 5 |
| 20 | R:R:Q187 | 7.202 | 5 | 1 | 2 |
| 21 | R:R:F208 | 6.81 | 5 | 1 | 7 |
| 22 | R:R:I209 | 4.92 | 4 | 1 | 5 |
| 23 | R:R:T212 | 6.07 | 5 | 1 | 4 |
| 24 | R:R:F217 | 4.87 | 4 | 1 | 8 |
| 25 | R:R:L221 | 4.0775 | 4 | 1 | 6 |
| 26 | R:R:Y228 | 6.988 | 5 | 1 | 9 |
| 27 | R:R:K236 | 5.2525 | 4 | 4 | 4 |
| 28 | R:R:E251 | 4.355 | 6 | 4 | 6 |
| 29 | R:R:V258 | 4.285 | 4 | 1 | 8 |
| 30 | R:R:W269 | 9.05333 | 6 | 1 | 8 |
| 31 | R:R:L270 | 4.8925 | 4 | 1 | 5 |
| 32 | R:R:F272 | 3.924 | 5 | 1 | 6 |
| 33 | R:R:N276 | 7.76 | 4 | 1 | 6 |
| 34 | R:R:K291 | 6.475 | 4 | 5 | 3 |
| 35 | R:R:F294 | 8.6125 | 4 | 1 | 4 |
| 36 | R:R:V297 | 4.2475 | 4 | 1 | 7 |
| 37 | R:R:Y302 | 11.568 | 5 | 1 | 7 |
| 38 | R:R:N308 | 8.2 | 4 | 1 | 9 |
| 39 | R:R:Y312 | 6.152 | 5 | 1 | 9 |
| 40 | R:R:F319 | 7.694 | 5 | 0 | 8 |
| Color | ConSurf Grade |
| No Conservation data available | |
| 1 | |
| 2 | |
| 3 | |
| 4 | |
| 5 | |
| 6 | |
| 7 | |
| 8 | |
| 9 |
Index: link id, click on each number to highlight the corresponding link in the 3D visualization.
Node1 Node2: the two nodes of the corresponding link.
Recurrence: the relative Recurrence in the pool of shortest paths.
Int. Strength: the interaction strength between the two nodes.
Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".
Community: the id of the community the link belong to, otherwise 0.
ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.
| Index | Node1 | Node2 | Recurrence | Int. Strength | Hub1? | Hub2? | Community | ConSurf1 | ConSurf2 |
|---|---|---|---|---|---|---|---|---|---|
| 1 | L:L:?1 | L:L:C2 | 13.0055 | 12.1 | Yes | No | 1 | 0 | 0 |
| 2 | L:L:C2 | R:R:F294 | 14.3812 | 13.97 | No | Yes | 1 | 0 | 4 |
| 3 | L:L:?1 | L:L:C7 | 12.9909 | 5.38 | Yes | Yes | 1 | 0 | 0 |
| 4 | L:L:C7 | R:R:F294 | 21.4596 | 5.59 | Yes | Yes | 1 | 0 | 4 |
| 5 | R:R:F294 | R:R:N276 | 35.9627 | 8.46 | Yes | Yes | 1 | 4 | 6 |
| 6 | L:L:?4 | R:R:N276 | 18.6253 | 7.63 | Yes | Yes | 1 | 0 | 6 |
| 7 | L:L:?4 | L:L:F3 | 27.7575 | 5.8 | Yes | Yes | 1 | 0 | 0 |
| 8 | L:L:?4 | L:L:K5 | 34.4846 | 22.39 | Yes | Yes | 0 | 0 | 0 |
| 9 | L:L:?4 | R:R:Q126 | 15.9471 | 6.34 | Yes | Yes | 1 | 0 | 7 |
| 10 | R:R:F272 | R:R:N276 | 19.8449 | 3.62 | Yes | Yes | 1 | 6 | 6 |
| 11 | L:L:K5 | R:R:V298 | 21.845 | 3.04 | Yes | No | 0 | 0 | 6 |
| 12 | L:L:K5 | R:R:Y302 | 12.586 | 7.17 | Yes | Yes | 0 | 0 | 7 |
| 13 | R:R:T301 | R:R:Y302 | 55.8515 | 3.75 | No | Yes | 1 | 7 | 7 |
| 14 | R:R:V298 | R:R:Y50 | 20.2839 | 3.79 | No | Yes | 0 | 6 | 7 |
| 15 | R:R:D295 | R:R:Y50 | 45.1632 | 3.45 | No | Yes | 0 | 2 | 7 |
| 16 | R:R:D295 | R:R:V103 | 38.7677 | 11.69 | No | Yes | 5 | 2 | 4 |
| 17 | R:R:Q102 | R:R:V103 | 34.4553 | 4.3 | Yes | Yes | 0 | 5 | 4 |
| 18 | R:R:V299 | R:R:Y50 | 10.6103 | 10.09 | No | Yes | 0 | 5 | 7 |
| 19 | R:R:I49 | R:R:V299 | 13.4885 | 3.07 | No | No | 0 | 5 | 5 |
| 20 | R:R:F296 | R:R:I49 | 11.264 | 1.26 | No | No | 0 | 5 | 5 |
| 21 | R:R:L96 | R:R:Y302 | 69.2961 | 16.41 | Yes | Yes | 0 | 7 | 7 |
| 22 | R:R:C54 | R:R:L96 | 39.1629 | 3.17 | Yes | Yes | 0 | 6 | 7 |
| 23 | R:R:L96 | R:R:V53 | 10.0346 | 2.98 | Yes | No | 0 | 7 | 7 |
| 24 | R:R:C54 | R:R:M93 | 32.4309 | 8.1 | Yes | No | 0 | 6 | 6 |
| 25 | R:R:L58 | R:R:M93 | 26.8696 | 5.65 | No | No | 0 | 6 | 6 |
| 26 | R:R:E90 | R:R:L58 | 25.4549 | 6.63 | No | No | 0 | 7 | 6 |
| 27 | R:R:E90 | R:R:I65 | 24.0304 | 6.83 | No | No | 0 | 7 | 7 |
| 28 | R:R:A86 | R:R:I65 | 19.7815 | 3.25 | No | No | 0 | 9 | 7 |
| 29 | R:R:A86 | R:R:V64 | 18.318 | 3.39 | No | No | 0 | 9 | 9 |
| 30 | R:R:A313 | R:R:V64 | 16.8447 | 5.09 | No | No | 0 | 7 | 9 |
| 31 | R:R:A313 | R:R:F319 | 15.3617 | 2.77 | No | Yes | 0 | 7 | 8 |
| 32 | R:R:F272 | R:R:W269 | 29.0843 | 3.01 | Yes | Yes | 1 | 6 | 8 |
| 33 | R:R:N304 | R:R:W269 | 100 | 9.04 | No | Yes | 1 | 9 | 8 |
| 34 | R:R:N304 | R:R:N308 | 99.922 | 9.54 | No | Yes | 1 | 9 | 9 |
| 35 | R:R:L133 | R:R:N308 | 78.3014 | 10.98 | No | Yes | 1 | 9 | 9 |
| 36 | R:R:L133 | R:R:Y312 | 83.648 | 5.86 | No | Yes | 1 | 9 | 9 |
| 37 | R:R:M136 | R:R:Y312 | 33.3431 | 5.99 | No | Yes | 0 | 9 | 9 |
| 38 | R:R:I82 | R:R:M136 | 32.0845 | 7.29 | No | No | 0 | 8 | 9 |
| 39 | R:R:I82 | R:R:N79 | 29.4941 | 4.25 | No | Yes | 0 | 8 | 8 |
| 40 | R:R:N79 | R:R:T78 | 22.7816 | 2.92 | Yes | No | 2 | 8 | 8 |
| 41 | R:R:D139 | R:R:T78 | 21.5669 | 2.89 | No | No | 0 | 8 | 8 |
| 42 | R:R:D139 | R:R:Y81 | 11.7713 | 8.05 | No | No | 0 | 8 | 7 |
| 43 | R:R:L85 | R:R:N308 | 18.0741 | 8.24 | No | Yes | 1 | 9 | 9 |
| 44 | R:R:C132 | R:R:L85 | 22.8645 | 7.94 | No | No | 0 | 8 | 9 |
| 45 | R:R:C132 | R:R:N84 | 20.1424 | 3.15 | No | No | 0 | 8 | 9 |
| 46 | R:R:N84 | R:R:T163 | 10.3078 | 13.16 | No | No | 0 | 9 | 7 |
| 47 | R:R:F92 | R:R:Q126 | 10.0102 | 10.54 | Yes | Yes | 1 | 6 | 7 |
| 48 | R:R:Q102 | R:R:W108 | 30.6893 | 9.86 | Yes | Yes | 0 | 5 | 8 |
| 49 | R:R:F110 | R:R:W108 | 11.703 | 2 | No | Yes | 0 | 6 | 8 |
| 50 | R:R:F127 | R:R:V173 | 14.4446 | 2.62 | Yes | No | 1 | 6 | 4 |
| 51 | R:R:L215 | R:R:V173 | 11.625 | 2.98 | No | No | 1 | 4 | 4 |
| 52 | R:R:I214 | R:R:L215 | 10.2395 | 9.99 | No | No | 0 | 4 | 4 |
| 53 | R:R:Y228 | R:R:Y312 | 54.1441 | 4.96 | Yes | Yes | 1 | 9 | 9 |
| 54 | R:R:S137 | R:R:Y228 | 45.4315 | 8.9 | No | Yes | 0 | 9 | 9 |
| 55 | R:R:C227 | R:R:S137 | 43.0606 | 3.44 | No | No | 0 | 7 | 9 |
| 56 | R:R:C227 | R:R:Y141 | 41.8606 | 8.06 | No | Yes | 0 | 7 | 8 |
| 57 | R:R:V145 | R:R:Y141 | 31.4601 | 11.36 | No | Yes | 6 | 7 | 8 |
| 58 | R:R:K234 | R:R:V145 | 30.6161 | 4.55 | No | No | 0 | 5 | 7 |
| 59 | L:L:F3 | R:R:I195 | 11.1518 | 2.51 | Yes | No | 0 | 0 | 5 |
| 60 | R:R:W269 | R:R:Y273 | 14.108 | 3.86 | Yes | No | 0 | 8 | 7 |
| 61 | R:R:F217 | R:R:Y273 | 17.2643 | 6.19 | Yes | No | 0 | 8 | 7 |
| 62 | R:R:K234 | R:R:S237 | 29.4063 | 7.65 | No | No | 0 | 5 | 5 |
| 63 | R:R:K236 | R:R:S237 | 28.0989 | 3.06 | Yes | No | 0 | 4 | 5 |
| 64 | R:R:E251 | R:R:K236 | 14.3373 | 6.75 | Yes | Yes | 4 | 6 | 4 |
| 65 | L:L:?1 | R:R:I284 | 14.6056 | 2.42 | Yes | No | 0 | 0 | 1 |
| 66 | R:R:I284 | R:R:L290 | 11.703 | 2.85 | No | No | 0 | 1 | 4 |
| 67 | R:R:Q126 | R:R:W269 | 23.8841 | 9.86 | Yes | Yes | 1 | 7 | 8 |
| 68 | L:L:?4 | R:R:F272 | 14.4788 | 3.87 | Yes | Yes | 1 | 0 | 6 |
| 69 | R:R:T301 | R:R:W269 | 47.8462 | 19.41 | No | Yes | 1 | 7 | 8 |
| 70 | R:R:L96 | R:R:Y50 | 34.5578 | 11.72 | Yes | Yes | 0 | 7 | 7 |
2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.
ConSurf Conservation Grade (See documentation):
n/a 1 2 3 4 5 6 7 8 9
2D representation of the interactions of this orthosteric/allosteric ligand. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Links and nodes colored according to ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9 |
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Location and physicochemical properties of the interaction partners of this ligand | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Interactions of this ligand | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Similarities between the interactions of this ligand and those of other networks | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Annotation | Type | Links |
|---|---|---|
| Gene Ontology | Molecular Function | |
| Gene Ontology | Biological Process | |
| Gene Ontology | Cellular Component | |
| SCOP2 | Domain Identifier | • Transducin (heterotrimeric G protein), gamma chain • WD40 repeat-like • Ras-like P-loop GTPases • G protein-coupled receptor-like |
| SCOP2 | Family Identifier | • Transducin (heterotrimeric G protein), gamma chain • WD40 repeat-like • Ras-like P-loop GTPases • G protein-coupled receptor-like |
| Membrane Protein Annotations | - | • Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD |
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| PDBsum | Open PDBsum Page |
| Chain | R |
| Protein | Receptor |
| UniProt | P30874 |
| Sequence | >7XAU_nogp_Chain_R TSNAVLTFI YFVVCIIGL CGNTLVIYV ILRYAKMKT ITNIYILNL AIADELFML GLPFLAMQV ALVHWPFGK AICRVVMTV DGINQFTSI FCLTVMSID RYLAVVHPI KSAKWRRPR TAKMITMAV WGVSLLVIL PIMIYAGLR SNQWGRSSC TINWPWYTG FIIYTFILG FLVPLTIIC LCYLFIIIK VKSSGIRVG SSKRKKSEK KVTRMVSIV VAVFIFCWL PFYIFNVSS VSMAISPTP ALKGMFDFV VVLTYANSC ANPILYAFL SDNFKKSFQ NV Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9 |
| This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks: | ||||||||||||
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| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
| 7XAT | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | Gi1/β1/γ2 | 2.85 | 2022-08-31 | doi.org/10.1038/s41421-022-00405-2 | |
| 7XAT (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | 2.85 | 2022-08-31 | doi.org/10.1038/s41421-022-00405-2 | ||
| 7XAU | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | Gi1/β1/γ2 | 2.97 | 2022-08-31 | doi.org/10.1038/s41421-022-00405-2 | |
| 7XAU (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | 2.97 | 2022-08-31 | doi.org/10.1038/s41421-022-00405-2 | ||
| 7XAV | A | Peptide | Somatostatin | SST2 | Homo sapiens | Lanreotide | - | Gi1/β1/γ2 | 2.87 | 2022-08-31 | doi.org/10.1038/s41421-022-00405-2 | |
| 7XAV (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Lanreotide | - | 2.87 | 2022-08-31 | doi.org/10.1038/s41421-022-00405-2 | ||
| 7WIC | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | Gi1/β1/γ2 | 2.8 | 2022-06-01 | doi.org/10.1038/s41422-022-00669-z | |
| 7WIC (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | 2.8 | 2022-06-01 | doi.org/10.1038/s41422-022-00669-z | ||
| 7WIG | A | Peptide | Somatostatin | SST2 | Homo sapiens | L-054,264 | - | Gi1/β1/γ2 | 2.7 | 2022-06-01 | doi.org/10.1038/s41422-022-00669-z | |
| 7WIG (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | L-054,264 | - | 2.7 | 2022-06-01 | doi.org/10.1038/s41422-022-00669-z | ||
| 7XMR | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | Gi1/β1/γ2 | 3.1 | 2022-08-03 | doi.org/10.1038/s41422-022-00679-x | |
| 7XMR (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | 3.1 | 2022-08-03 | doi.org/10.1038/s41422-022-00679-x | ||
| 7XN9 | A | Peptide | Somatostatin | SST2 | Homo sapiens | L-054,522 | - | - | 2.6 | 2022-08-03 | doi.org/10.1038/s41422-022-00679-x | |
| 7XNA | A | Peptide | Somatostatin | SST2 | Homo sapiens | CYN154806 | - | - | 2.65 | 2022-08-03 | doi.org/10.1038/s41422-022-00679-x | |
| 7YAC | A | Peptide | Somatostatin | SST2 | Homo sapiens | Paltusotine | - | Gi1/β1/γ2 | 3.24 | 2023-04-19 | doi.org/10.1038/s41467-023-36673-z | |
| 7YAC (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Paltusotine | - | 3.24 | 2023-04-19 | doi.org/10.1038/s41467-023-36673-z | ||
| 7YAE | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | Gi1/β1/γ2 | 3.37 | 2023-04-19 | doi.org/10.1038/s41467-023-36673-z | |
| 7YAE (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | 3.37 | 2023-04-19 | doi.org/10.1038/s41467-023-36673-z | ||
| 7Y24 | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | Go/β1/γ2 | 3.25 | 2022-10-19 | doi.org/10.1038/s41589-022-01130-3 | |
| 7Y24 (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | 3.25 | 2022-10-19 | doi.org/10.1038/s41589-022-01130-3 | ||
| 7Y26 | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | chim(NtGi2L-Gs-CtGq)/β1/γ2 | 3.3 | 2022-10-19 | doi.org/10.1038/s41589-022-01130-3 | |
| 7Y26 (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | 3.3 | 2022-10-19 | doi.org/10.1038/s41589-022-01130-3 | ||
| 7Y27 | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | chim(NtGi2L-Gs-CtGq)/β1/γ2 | 3.48 | 2022-10-19 | doi.org/10.1038/s41589-022-01130-3 | |
| 7Y27 (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | 3.48 | 2022-10-19 | doi.org/10.1038/s41589-022-01130-3 | ||
| 7UL5 | A | Peptide | Somatostatin | SST2 | Homo sapiens | - | - | - | 3.1 | 2022-06-29 | doi.org/10.1038/s41594-022-00859-8 | |
| 7WJ5 | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | Gi1/β1/γ2 | 3.72 | 2022-07-13 | doi.org/10.7554/eLife.76823 | |
| 7WJ5 (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | 3.72 | 2022-07-13 | doi.org/10.7554/eLife.76823 | ||
| 7T10 | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | Gi3/β1/γ2 | 2.5 | 2022-03-09 | doi.org/10.1038/s41594-022-00727-5 | |
| 7T10 (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Somatostatin-14 | - | 2.5 | 2022-03-09 | doi.org/10.1038/s41594-022-00727-5 | ||
| 7T11 | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | Gi3/β1/γ2 | 2.7 | 2022-03-09 | doi.org/10.1038/s41594-022-00727-5 | |
| 7T11 (No Gprot) | A | Peptide | Somatostatin | SST2 | Homo sapiens | Octreotide | - | 2.7 | 2022-03-09 | doi.org/10.1038/s41594-022-00727-5 | ||
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