psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:P2	L:L:Y1	5.56	No	No	0	0	0
2	L:L:Y1	R:R:E188	5.61	No	Yes	1	0	4
3	L:L:Y1	R:R:K206	5.97	No	No	1	0	3
4	L:L:P2	L:L:Y27	9.74	No	No	0	0	0
5	L:L:I31	L:L:P2	6.77	Yes	No	0	0	0
6	L:L:K4	L:L:P5	3.35	Yes	Yes	1	0	0
7	L:L:K4	L:L:Y27	11.94	Yes	No	1	0	0
8	L:L:K4	R:R:I192	4.36	Yes	No	1	0	2
9	L:L:K4	R:R:I194	4.36	Yes	No	1	0	1
10	L:L:P5	L:L:Y20	6.95	Yes	Yes	1	0	0
11	L:L:L24	L:L:P5	4.93	Yes	Yes	1	0	0
12	L:L:M17	L:L:Y20	3.59	No	Yes	1	0	0
13	L:L:M17	L:L:Y21	3.59	No	No	1	0	0
14	L:L:Y20	L:L:Y21	2.98	Yes	No	1	0	0
15	L:L:L24	L:L:Y20	3.52	Yes	Yes	1	0	0
16	L:L:Y21	R:R:L40	5.86	No	No	0	0	7
17	L:L:I28	L:L:L24	4.28	No	Yes	0	0	0
18	L:L:R25	R:R:S43	3.95	No	No	0	0	5
19	L:L:R25	R:R:L300	13.36	No	No	0	0	1
20	L:L:H26	R:R:V297	4.15	No	No	0	0	6
21	L:L:Y27	R:R:I192	9.67	No	No	1	0	2
22	L:L:N29	R:R:V297	4.43	No	No	2	0	6
23	L:L:N29	R:R:Y303	3.49	No	Yes	2	0	4
24	L:L:I31	L:L:T32	3.04	Yes	No	0	0	0
25	L:L:I31	R:R:I192	4.42	Yes	No	1	0	2
26	L:L:I31	R:R:A202	3.25	Yes	No	1	0	4
27	L:L:I31	R:R:T204	4.56	Yes	No	1	0	4
28	L:L:T32	R:R:Y110	11.24	No	No	0	0	5
29	L:L:R33	L:L:R35	8.53	Yes	Yes	2	0	0
30	L:L:R33	R:R:E205	3.49	Yes	No	0	0	4
31	L:L:R33	R:R:Q288	3.5	Yes	No	2	0	5
32	L:L:R33	R:R:V291	10.46	Yes	No	2	0	4
33	L:L:R33	R:R:D292	11.91	Yes	No	2	0	5
34	L:L:Q34	R:R:T107	7.09	Yes	No	0	0	6
35	L:L:Q34	R:R:Y110	12.4	Yes	No	0	0	5
36	L:L:Q34	R:R:T111	4.25	Yes	No	0	0	4
37	L:L:Q34	R:R:F307	4.68	Yes	No	0	0	4
38	L:L:R35	L:L:Y36	3.09	Yes	Yes	0	0	0
39	L:L:R35	R:R:Y219	11.32	Yes	Yes	0	0	6
40	L:L:R35	R:R:Q288	5.84	Yes	No	2	0	5
41	L:L:R35	R:R:D292	7.15	Yes	No	2	0	5
42	L:L:Y36	R:R:Q130	3.38	Yes	No	0	0	6
43	L:L:Y36	R:R:S223	3.82	Yes	No	0	0	5
44	L:L:Y36	R:R:H285	6.53	Yes	No	0	0	7
45	R:R:E39	R:R:I41	15.03	No	No	0	3	3
46	R:R:K301	R:R:T44	3	No	No	0	3	4
47	R:R:K304	R:R:K45	4.31	No	No	0	4	3
48	R:R:E48	R:R:L46	9.28	No	No	0	2	2
49	R:R:I47	R:R:V51	3.07	No	No	0	2	6
50	R:R:I54	R:R:Q50	5.49	No	No	0	6	4
51	R:R:L112	R:R:Q50	3.99	No	No	0	4	4
52	R:R:L55	R:R:V51	2.98	No	No	0	6	6
53	R:R:L53	R:R:T308	7.37	No	No	0	5	3
54	R:R:L108	R:R:Y57	8.21	No	Yes	0	6	7
55	R:R:T308	R:R:Y57	6.24	No	Yes	0	3	7
56	R:R:H311	R:R:Y57	4.36	Yes	Yes	0	5	7
57	R:R:I312	R:R:Y57	7.25	No	Yes	0	5	7
58	R:R:I312	R:R:I60	7.36	No	No	0	5	7
59	R:R:F319	R:R:I60	6.28	No	No	0	7	7
60	R:R:I61	R:R:N100	9.91	No	Yes	0	6	6
61	R:R:F319	R:R:L63	3.65	No	No	0	7	6
62	R:R:L97	R:R:V65	2.98	No	No	0	7	6
63	R:R:N100	R:R:V65	4.43	Yes	No	0	6	6
64	R:R:A93	R:R:N68	3.13	No	Yes	0	9	9
65	R:R:D96	R:R:N68	6.73	No	Yes	0	9	9
66	R:R:L97	R:R:N68	8.24	No	Yes	0	7	9
67	R:R:N68	R:R:P322	6.52	Yes	No	0	9	9
68	R:R:F336	R:R:L70	7.31	No	No	0	6	7
69	R:R:A93	R:R:V71	3.39	No	No	0	9	9
70	R:R:A93	R:R:I72	3.25	No	No	0	9	7
71	R:R:I72	R:R:V94	3.07	No	No	0	7	6
72	R:R:H73	R:R:K77	3.93	No	No	0	4	5
73	R:R:F336	R:R:V74	9.18	No	No	0	6	7
74	R:R:A90	R:R:V75	5.09	No	No	0	6	7
75	R:R:V75	R:R:Y332	5.05	No	Yes	0	7	8
76	R:R:F78	R:R:K77	12.41	Yes	No	0	5	5
77	R:R:A335	R:R:F78	4.16	No	Yes	0	6	5
78	R:R:K79	R:R:R82	9.9	No	No	0	6	6
79	R:R:M81	R:R:N86	9.82	No	No	7	8	8
80	R:R:M81	R:R:Y332	5.99	No	Yes	7	8	8
81	R:R:F87	R:R:R82	7.48	No	No	0	5	6
82	R:R:N86	R:R:T83	8.77	No	No	0	8	7
83	R:R:F88	R:R:V84	5.24	Yes	No	3	7	6
84	R:R:S165	R:R:V84	6.46	No	No	3	7	6
85	R:R:D147	R:R:T85	7.23	No	No	0	8	8
86	R:R:N86	R:R:Y332	10.47	No	Yes	7	8	8
87	R:R:F88	R:R:V143	6.55	Yes	No	0	7	7
88	R:R:F88	R:R:I144	5.02	Yes	Yes	3	7	9
89	R:R:D147	R:R:F88	4.78	No	Yes	0	8	7
90	R:R:F88	R:R:S165	5.28	Yes	No	3	7	7
91	R:R:I89	R:R:Y332	13.3	No	Yes	0	8	8
92	R:R:N91	R:R:T140	13.16	No	No	0	9	8
93	R:R:N91	R:R:W173	5.65	No	Yes	0	9	9
94	R:R:L92	R:R:T140	7.37	No	No	0	9	8
95	R:R:L141	R:R:L92	5.54	No	No	0	8	9
96	R:R:L92	R:R:N321	4.12	No	No	0	9	9
97	R:R:A95	R:R:V136	3.39	No	No	0	8	7
98	R:R:D96	R:R:S137	4.42	No	No	0	9	9
99	R:R:D96	R:R:N321	6.73	No	No	0	9	9
100	R:R:M315	R:R:V99	3.04	Yes	No	0	7	7
101	R:R:L104	R:R:N100	4.12	No	Yes	0	7	6
102	R:R:N100	R:R:T318	4.39	Yes	No	0	6	9
103	R:R:C103	R:R:H311	4.42	No	Yes	6	6	5
104	R:R:C103	R:R:M315	4.86	No	Yes	6	6	7
105	R:R:L104	R:R:P105	3.28	No	No	0	7	8
106	R:R:L104	R:R:M315	4.24	No	Yes	0	7	7
107	R:R:F106	R:R:V126	10.49	No	No	0	5	5
108	R:R:H311	R:R:T107	6.85	Yes	No	0	5	6
109	R:R:L108	R:R:L112	6.92	No	No	0	6	4
110	R:R:W116	R:R:Y110	9.65	Yes	No	0	8	5
111	R:R:K304	R:R:T111	3	No	No	0	4	4
112	R:R:E115	R:R:E199	3.81	No	No	0	5	4
113	R:R:E115	R:R:I200	8.2	No	No	0	5	3
114	R:R:M118	R:R:W116	13.96	No	Yes	0	7	8
115	R:R:C123	R:R:W116	6.53	No	Yes	8	9	8
116	R:R:C203	R:R:W116	9.14	No	Yes	8	9	8
117	R:R:L122	R:R:M118	5.65	No	No	0	6	7
118	R:R:G119	R:R:P120	4.06	No	No	0	8	3
119	R:R:H124	R:R:P120	3.05	No	No	0	7	3
120	R:R:P120	R:R:Y189	11.13	No	No	0	3	5
121	R:R:L122	R:R:V121	2.98	No	No	0	6	2
122	R:R:C123	R:R:C203	7.28	No	No	8	9	9
123	R:R:H124	R:R:R187	4.51	No	No	0	7	6
124	R:R:P127	R:R:V126	3.53	Yes	No	0	5	5
125	R:R:P127	R:R:Q130	4.74	Yes	No	0	5	6
126	R:R:L183	R:R:P127	6.57	No	Yes	0	5	5
127	R:R:P127	R:R:R187	5.76	Yes	No	0	5	6
128	R:R:L132	R:R:Y128	3.52	Yes	No	0	5	6
129	R:R:A180	R:R:Y128	4	No	No	0	7	6
130	R:R:L132	R:R:W173	4.56	Yes	Yes	0	5	9
131	R:R:L132	R:R:S176	3	Yes	No	0	5	8
132	R:R:Q135	R:R:S176	8.66	No	No	0	6	8
133	R:R:L179	R:R:Q135	11.98	No	No	0	5	6
134	R:R:L227	R:R:Q135	5.32	No	No	0	6	6
135	R:R:V136	R:R:W173	11.03	No	Yes	0	7	9
136	R:R:S176	R:R:V136	3.23	No	No	0	8	7
137	R:R:L227	R:R:T138	4.42	No	No	0	6	8
138	R:R:P231	R:R:T138	3.5	No	No	0	9	8
139	R:R:A172	R:R:I139	4.87	No	No	0	7	5
140	R:R:L141	R:R:Y325	5.86	No	Yes	0	8	9
141	R:R:I234	R:R:T142	3.04	No	No	0	6	7
142	R:R:I144	R:R:R148	3.76	Yes	No	3	9	9
143	R:R:I144	R:R:Y325	4.84	Yes	Yes	3	9	9
144	R:R:A145	R:R:Y239	4	No	Yes	0	9	9
145	R:R:R148	R:R:Y239	9.26	No	Yes	0	9	9
146	R:R:R148	R:R:Y325	5.14	No	Yes	3	9	9
147	R:R:H149	R:R:V153	19.37	No	No	9	8	7
148	R:R:H149	R:R:S238	8.37	No	No	0	8	7
149	R:R:H149	R:R:R241	7.9	No	No	9	8	4
150	R:R:I160	R:R:R150	5.01	No	No	0	5	4
151	R:R:C151	R:R:K159	3.23	No	No	0	8	5
152	R:R:I152	R:R:I242	7.36	No	No	0	8	8
153	R:R:V153	R:R:Y154	7.57	No	No	0	7	7
154	R:R:R241	R:R:V153	3.92	No	No	9	4	7
155	R:R:E157	R:R:Y154	4.49	No	No	0	4	7
156	R:R:H155	R:R:L156	6.43	No	No	0	8	5
157	R:R:H155	R:R:K245	7.86	No	No	0	8	5
158	R:R:E157	R:R:L156	3.98	No	No	0	4	5
159	R:R:I160	R:R:I164	4.42	No	No	0	5	5
160	R:R:R163	R:R:S161	14.5	No	No	10	5	6
161	R:R:I164	R:R:S161	3.1	No	No	10	5	6
162	R:R:I164	R:R:R163	3.76	No	No	10	5	5
163	R:R:G170	R:R:I169	3.53	No	No	0	4	7
164	R:R:P182	R:R:S181	3.56	No	No	0	8	4
165	R:R:I185	R:R:S181	4.64	No	No	0	4	4
166	R:R:L183	R:R:Y219	7.03	No	Yes	0	5	6
167	R:R:F186	R:R:I185	7.54	No	No	0	5	4
168	R:R:F186	R:R:W207	10.02	No	Yes	4	5	5
169	R:R:F186	R:R:P208	4.33	No	No	4	5	4
170	R:R:C203	R:R:R187	4.18	No	No	0	9	6
171	R:R:E188	R:R:T204	4.23	Yes	No	1	4	4
172	R:R:E188	R:R:K206	13.5	Yes	No	1	4	3
173	R:R:V201	R:R:Y189	12.62	No	No	0	4	5
174	R:R:E199	R:R:L191	5.3	No	No	0	4	3
175	R:R:L191	R:R:V201	2.98	No	No	0	3	4
176	R:R:I194	R:R:P196	3.39	No	No	1	1	3
177	R:R:F198	R:R:I194	7.54	No	No	1	1	1
178	R:R:I195	R:R:P196	5.08	No	No	0	2	3
179	R:R:F198	R:R:P196	8.67	No	No	1	1	3
180	R:R:A202	R:R:T204	3.36	No	No	1	4	4
181	R:R:E205	R:R:W207	6.54	No	Yes	0	4	5
182	R:R:P208	R:R:W207	6.76	No	Yes	4	4	5
183	R:R:W207	R:R:Y215	4.82	Yes	No	4	5	3
184	R:R:W207	R:R:Y219	3.86	Yes	Yes	0	5	6
185	R:R:P208	R:R:Y215	4.17	No	No	4	4	3
186	R:R:E210	R:R:E211	3.81	No	No	0	1	2
187	R:R:S213	R:R:Y215	6.36	No	No	0	2	3
188	R:R:L289	R:R:S220	6.01	No	No	0	5	4
189	R:R:D292	R:R:S220	7.36	No	No	0	5	4
190	R:R:L225	R:R:V229	2.98	No	No	0	5	4
191	R:R:L232	R:R:Y228	3.52	Yes	No	0	5	8
192	R:R:L282	R:R:Y228	3.52	No	No	0	5	8
193	R:R:L230	R:R:P231	3.28	No	No	0	6	9
194	R:R:I235	R:R:Y239	4.84	No	Yes	0	8	9
195	R:R:F237	R:R:R241	9.62	No	No	0	4	4
196	R:R:L270	R:R:Y239	5.86	No	Yes	0	8	9
197	R:R:K247	R:R:W243	10.44	No	Yes	5	6	5
198	R:R:R263	R:R:W243	5	Yes	Yes	5	7	5
199	R:R:T267	R:R:W243	7.28	No	Yes	5	6	5
200	R:R:N248	R:R:S244	2.98	No	No	0	4	4
201	R:R:L246	R:R:R263	13.36	No	Yes	0	8	7
202	R:R:K247	R:R:R263	7.43	No	Yes	5	6	7
203	R:R:H249	R:R:Y259	15.24	No	No	0	6	4
204	R:R:P252	R:R:S251	3.56	No	No	11	4	4
205	R:R:N256	R:R:S251	10.43	No	No	11	4	4
206	R:R:N256	R:R:P252	8.15	No	No	11	4	4
207	R:R:H258	R:R:Q261	4.95	No	No	0	4	4
208	R:R:H258	R:R:R262	14.67	No	No	0	4	5
209	R:R:H260	R:R:Y259	3.27	No	No	0	4	4
210	R:R:R263	R:R:T266	10.35	Yes	No	0	7	8
211	R:R:R263	R:R:T267	10.35	Yes	No	5	7	6
212	R:R:K268	R:R:Q264	5.42	No	No	0	6	5
213	R:R:K265	R:R:M328	4.32	No	No	0	8	7
214	R:R:K268	R:R:T267	3	No	No	0	6	6
215	R:R:M269	R:R:M328	11.55	No	No	0	8	7
216	R:R:L324	R:R:V273	5.96	No	No	0	8	8
217	R:R:V273	R:R:Y325	6.31	No	Yes	0	8	9
218	R:R:L324	R:R:V276	4.47	No	No	0	8	6
219	R:R:S280	R:R:S317	4.89	No	No	0	8	9
220	R:R:H285	R:R:W281	5.29	No	Yes	0	7	8
221	R:R:A314	R:R:W281	3.89	No	Yes	0	7	8
222	R:R:S317	R:R:W281	4.94	No	Yes	0	9	8
223	R:R:L282	R:R:P283	4.93	No	No	0	5	9
224	R:R:F310	R:R:P283	10.11	No	No	0	6	9
225	R:R:H311	R:R:L284	3.86	Yes	No	0	5	6
226	R:R:A314	R:R:L284	4.73	No	No	0	7	6
227	R:R:F287	R:R:V291	5.24	Yes	No	2	4	4
228	R:R:F287	R:R:Y303	9.28	Yes	Yes	2	4	4
229	R:R:F287	R:R:I306	3.77	Yes	No	0	4	5
230	R:R:F287	R:R:F307	4.29	Yes	No	0	4	4
231	R:R:F287	R:R:F310	3.22	Yes	No	0	4	6
232	R:R:F307	R:R:Q288	4.68	No	No	0	4	5
233	R:R:V291	R:R:Y303	6.31	No	Yes	2	4	4
234	R:R:D294	R:R:Q296	9.14	No	No	0	2	5
235	R:R:L298	R:R:Q296	11.98	No	No	0	1	5
236	R:R:V297	R:R:Y303	5.05	No	Yes	2	6	4
237	R:R:E302	R:R:L305	6.63	No	No	0	3	1
238	R:R:H311	R:R:M315	10.51	Yes	Yes	6	5	7
239	R:R:C316	R:R:F319	6.98	No	No	0	5	7
240	R:R:G326	R:R:Y332	4.35	No	Yes	0	7	8
241	R:R:R333	R:R:W327	9	No	No	0	8	6
242	R:R:N329	R:R:Y332	9.3	No	Yes	0	8	8
243	R:R:I144	R:R:I89	2.94	Yes	No	0	9	8
244	L:L:L24	R:R:I41	2.85	Yes	No	0	0	3
245	R:R:I47	R:R:L46	2.85	No	No	0	2	2
246	R:R:I234	R:R:L146	2.85	No	No	0	6	6
247	R:R:I175	R:R:L171	2.85	No	No	0	4	3
248	R:R:I293	R:R:L289	2.85	No	No	0	4	5
249	R:R:I169	R:R:N91	2.83	No	No	0	7	9
250	R:R:D42	R:R:K45	2.77	No	No	0	3	3
251	R:R:L221	R:R:L225	2.77	No	No	0	4	5
252	R:R:L224	R:R:L225	2.77	No	No	0	5	5
253	R:R:L224	R:R:L289	2.77	No	No	0	5	5
254	L:L:N29	R:R:L300	2.75	No	No	0	0	1
255	L:L:L30	R:R:E205	2.65	No	No	0	0	4
256	R:R:F78	R:R:S338	2.64	Yes	No	0	5	4
257	R:R:F87	R:R:S165	2.64	No	No	0	5	7
258	R:R:F78	R:R:V74	2.62	Yes	No	0	5	7
259	R:R:D299	R:R:E302	2.6	No	No	0	1	3
260	R:R:E193	R:R:E199	2.54	No	No	0	2	4
261	R:R:S238	R:R:Y239	2.54	No	Yes	0	7	9
262	R:R:V74	R:R:Y332	2.52	No	Yes	0	7	8
263	R:R:V274	R:R:Y239	2.52	No	Yes	0	8	9
264	R:R:F88	R:R:I168	2.51	Yes	No	0	7	5
265	R:R:M328	R:R:R333	2.48	No	No	0	7	8
266	R:R:V134	R:R:W281	2.45	No	Yes	0	7	8
267	R:R:F277	R:R:L141	2.44	No	No	0	9	8
268	R:R:F277	R:R:L232	2.44	No	Yes	0	9	5
269	R:R:I242	R:R:Y239	2.42	No	Yes	0	8	9
270	R:R:L246	R:R:Y259	2.34	No	No	0	8	4
271	R:R:L98	R:R:W173	2.28	No	Yes	0	7	9
272	R:R:F166	R:R:F87	2.14	No	No	0	4	5
273	R:R:A177	R:R:G174	1.95	No	No	0	4	4
274	L:L:A23	L:L:P5	1.87	No	Yes	0	0	0
275	R:R:G67	R:R:I66	1.76	No	No	0	8	4
276	L:L:G9	L:L:M17	1.75	No	No	0	0	0
277	R:R:G114	R:R:M113	1.75	No	No	0	5	4
278	R:R:P231	R:R:T142	1.75	No	No	0	9	7
279	R:R:G64	R:R:L63	1.71	No	No	0	7	6
280	R:R:G131	R:R:L183	1.71	No	No	0	4	5
281	R:R:G233	R:R:L232	1.71	No	Yes	0	3	5
282	R:R:A339	R:R:S338	1.71	No	No	0	4	4
283	R:R:A133	R:R:V99	1.7	No	No	0	7	7
284	R:R:A320	R:R:V276	1.7	No	No	0	6	6
285	R:R:I313	R:R:P283	1.69	No	No	0	7	9
286	R:R:C58	R:R:I54	1.64	No	No	0	4	6
287	L:L:N7	L:L:P8	1.63	No	No	0	0	0
288	R:R:S69	R:R:V65	1.62	No	No	0	4	6
289	R:R:S222	R:R:V218	1.62	No	No	0	3	4
290	R:R:C272	R:R:M269	1.62	No	No	0	6	8
291	R:R:S236	R:R:T240	1.6	No	No	0	5	3
292	R:R:V271	R:R:V275	1.6	No	No	0	6	4
293	R:R:V275	R:R:V279	1.6	No	No	0	4	6
294	R:R:A129	R:R:L102	1.58	No	No	0	5	5
295	R:R:A177	R:R:L132	1.58	No	Yes	0	4	5
296	R:R:A278	R:R:L232	1.58	No	Yes	0	5	5
297	R:R:C151	R:R:D147	1.56	No	No	0	8	8
298	R:R:I139	R:R:V143	1.54	No	No	0	5	7
299	R:R:K301	R:R:S43	1.53	No	No	0	3	5
300	R:R:I293	R:R:T217	1.52	No	No	0	4	3
301	R:R:L63	R:R:S59	1.5	No	No	0	6	5
302	R:R:L46	R:R:V49	1.49	No	No	0	2	4
303	R:R:L53	R:R:V49	1.49	No	No	0	5	4
304	R:R:L305	R:R:V49	1.49	No	No	0	1	4
305	R:R:L53	R:R:V52	1.49	No	No	0	5	5
306	R:R:I72	R:R:I76	1.47	No	No	0	7	3
307	R:R:L270	R:R:T266	1.47	No	No	0	8	8
308	R:R:G216	R:R:Y219	1.45	No	Yes	0	4	6
309	R:R:E188	R:R:S190	1.44	Yes	No	0	4	1
310	R:R:I175	R:R:L178	1.43	No	No	0	4	4
311	R:R:I226	R:R:L227	1.43	No	No	0	4	6
312	R:R:I226	R:R:L230	1.43	No	No	0	4	6
313	R:R:L112	R:R:M113	1.41	No	No	0	4	4
314	R:R:L324	R:R:M269	1.41	No	No	0	8	8
315	R:R:M81	R:R:N331	1.4	No	No	0	8	6
316	R:R:D294	R:R:I293	1.4	No	No	0	2	4
317	L:L:D6	L:L:N7	1.35	No	No	0	0	0
318	R:R:E210	R:R:K212	1.35	No	No	0	1	3
319	R:R:A184	R:R:Y128	1.33	No	No	0	5	6
320	R:R:D257	R:R:Q261	1.31	No	No	0	4	4
321	R:R:F310	R:R:V309	1.31	No	No	0	6	6
322	R:R:F106	R:R:T109	1.3	No	No	0	5	4
323	R:R:H124	R:R:L125	1.29	No	No	0	7	5
324	R:R:S244	R:R:W243	1.24	No	Yes	0	4	5
325	R:R:F106	R:R:L102	1.22	No	No	0	5	5
326	R:R:L337	R:R:R333	1.21	No	No	0	4	8
327	L:L:D16	L:L:R19	1.19	No	No	0	0	0
328	R:R:E157	R:R:R150	1.16	No	No	0	4	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:K4	6.0025	4	1	0
2	L:L:P5	4.275	4	1	0
3	L:L:Y20	4.26	4	1	0
4	L:L:L24	3.895	4	1	0
5	L:L:I31	4.408	5	1	0
6	L:L:R33	7.578	5	2	0
7	L:L:Q34	7.105	4	0	0
8	L:L:R35	7.186	5	2	0
9	L:L:Y36	4.205	4	0	0
10	R:R:Y57	6.515	4	0	7
11	R:R:N68	6.155	4	0	9
12	R:R:F78	5.4575	4	0	5
13	R:R:F88	4.89667	6	3	7
14	R:R:N100	5.7125	4	0	6
15	R:R:W116	9.82	4	8	8
16	R:R:P127	5.15	4	0	5
17	R:R:L132	3.165	4	0	5
18	R:R:I144	4.14	4	3	9
19	R:R:W173	5.88	4	0	9
20	R:R:E188	6.195	4	1	4
21	R:R:W207	6.4	5	4	5
22	R:R:Y219	5.915	4	0	6
23	R:R:L232	2.3125	4	0	5
24	R:R:Y239	4.49143	7	0	9
25	R:R:W243	5.99	4	5	5
26	R:R:R263	9.298	5	5	7
27	R:R:W281	4.1425	4	0	8
28	R:R:F287	5.16	5	2	4
29	R:R:Y303	6.0325	4	2	4
30	R:R:H311	6	5	6	5
31	R:R:M315	5.6625	4	6	7
32	R:R:Y325	5.5375	4	3	9
33	R:R:Y332	7.28286	7	7	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:K4	L:L:P5	16.3217	3.35	Yes	Yes	1	0	0
2	L:L:I31	R:R:I192	25.6751	4.42	Yes	No	1	0	2
3	L:L:I31	L:L:T32	39.2667	3.04	Yes	No	0	0	0
4	L:L:T32	R:R:Y110	40.4889	11.24	No	No	0	0	5
5	L:L:Q34	R:R:Y110	57.9785	12.4	Yes	No	0	0	5
6	L:L:Q34	R:R:F307	64.4589	4.68	Yes	No	0	0	4
7	R:R:F287	R:R:F307	59.5801	4.29	Yes	No	0	4	4
8	R:R:F287	R:R:Y303	10.6052	9.28	Yes	Yes	2	4	4
9	R:R:F307	R:R:Q288	38.3255	4.68	No	No	0	4	5
10	L:L:R33	R:R:Q288	10.2848	3.5	Yes	No	2	0	5
11	L:L:R35	R:R:Q288	27.3704	5.84	Yes	No	2	0	5
12	L:L:R33	R:R:E205	12.2856	3.49	Yes	No	0	0	4
13	R:R:F287	R:R:V291	32.2541	5.24	Yes	No	2	4	4
14	L:L:R33	R:R:D292	14.7102	11.91	Yes	No	2	0	5
15	L:L:Q34	R:R:T107	33.6783	7.09	Yes	No	0	0	6
16	L:L:R35	L:L:Y36	21.8017	3.09	Yes	Yes	0	0	0
17	L:L:R35	R:R:Y219	21.9988	11.32	Yes	Yes	0	0	6
18	R:R:W116	R:R:Y110	24.2362	9.65	Yes	No	0	8	5
19	R:R:C203	R:R:W116	18.495	9.14	No	Yes	8	9	8
20	R:R:C203	R:R:R187	17.9874	4.18	No	No	0	9	6
21	R:R:P127	R:R:Q130	13.1924	4.74	Yes	No	0	5	6
22	R:R:H311	R:R:T107	33.0672	6.85	Yes	No	0	5	6
23	R:R:H311	R:R:Y57	38.8478	4.36	Yes	Yes	0	5	7
24	R:R:T308	R:R:Y57	18.15	6.24	No	Yes	0	3	7
25	R:R:L53	R:R:T308	16.6913	7.37	No	No	0	5	3
26	R:R:L53	R:R:V49	13.7443	1.49	No	No	0	5	4
27	R:R:L108	R:R:Y57	10.7579	8.21	No	Yes	0	6	7
28	R:R:I312	R:R:Y57	10.7579	7.25	No	Yes	0	5	7
29	R:R:H311	R:R:M315	37.7045	10.51	Yes	Yes	6	5	7
30	R:R:L104	R:R:M315	37.877	4.24	No	Yes	0	7	7
31	R:R:L104	R:R:N100	37.532	4.12	No	Yes	0	7	6
32	R:R:N100	R:R:V65	36.9702	4.43	Yes	No	0	6	6
33	R:R:L97	R:R:V65	36.5661	2.98	No	No	0	7	6
34	R:R:L97	R:R:N68	36.369	8.24	No	Yes	0	7	9
35	R:R:D96	R:R:N68	34.8512	6.73	No	Yes	0	9	9
36	R:R:F287	R:R:F310	91.7406	3.22	Yes	No	0	4	6
37	R:R:F310	R:R:P283	91.3069	10.11	No	No	0	6	9
38	R:R:L282	R:R:P283	90.8535	4.93	No	No	0	5	9
39	R:R:L282	R:R:Y228	90.6318	3.52	No	No	0	5	8
40	R:R:L232	R:R:Y228	90.4297	3.52	Yes	No	0	5	8
41	R:R:F277	R:R:L232	89.8236	2.44	No	Yes	0	9	5
42	R:R:F277	R:R:L141	89.6363	2.44	No	No	0	9	8
43	R:R:L141	R:R:Y325	100	5.86	No	Yes	0	8	9
44	R:R:I144	R:R:Y325	44.3229	4.84	Yes	Yes	3	9	9
45	R:R:I144	R:R:I89	28.8981	2.94	Yes	No	0	9	8
46	R:R:I89	R:R:Y332	27.464	13.3	No	Yes	0	8	8
47	R:R:V74	R:R:Y332	14.1435	2.52	No	Yes	0	7	8
48	R:R:F88	R:R:I144	23.1323	5.02	Yes	Yes	3	7	9
49	R:R:L141	R:R:L92	65.8338	5.54	No	No	0	8	9
50	R:R:L92	R:R:T140	50.5569	7.37	No	No	0	9	8
51	R:R:N91	R:R:T140	49.3249	13.16	No	No	0	9	8
52	R:R:N91	R:R:W173	45.5697	5.65	No	Yes	0	9	9
53	R:R:D96	R:R:N321	34.792	6.73	No	No	0	9	9
54	R:R:V136	R:R:W173	18.697	11.03	No	Yes	0	7	9
55	R:R:P127	R:R:V126	18.8941	3.53	Yes	No	0	5	5
56	R:R:F106	R:R:V126	15.134	10.49	No	No	0	5	5
57	R:R:H124	R:R:R187	17.1792	4.51	No	No	0	7	6
58	R:R:H124	R:R:P120	14.1435	3.05	No	No	0	7	3
59	R:R:P120	R:R:Y189	11.0684	11.13	No	No	0	3	5
60	R:R:L183	R:R:P127	12.3596	6.57	No	Yes	0	5	5
61	R:R:L132	R:R:W173	24.4333	4.56	Yes	Yes	0	5	9
62	R:R:L132	R:R:S176	16.1542	3	Yes	No	0	5	8
63	R:R:S176	R:R:V136	15.9373	3.23	No	No	0	8	7
64	R:R:Q135	R:R:S176	29.1199	8.66	No	No	0	6	8
65	R:R:L227	R:R:Q135	23.3737	5.32	No	No	0	6	6
66	R:R:L227	R:R:T138	14.6363	4.42	No	No	0	6	8
67	R:R:P231	R:R:T138	11.7288	3.5	No	No	0	9	8
68	R:R:R148	R:R:Y325	45.3528	5.14	No	Yes	3	9	9
69	R:R:R148	R:R:Y239	50.2809	9.26	No	Yes	0	9	9
70	R:R:S238	R:R:Y239	23.014	2.54	No	Yes	0	7	9
71	R:R:H149	R:R:S238	21.5405	8.37	No	No	0	8	7
72	R:R:H149	R:R:V153	16.9525	19.37	No	No	9	8	7
73	R:R:V153	R:R:Y154	15.5381	7.57	No	No	0	7	7
74	R:R:E157	R:R:Y154	14.0154	4.49	No	No	0	4	7
75	R:R:E205	R:R:W207	10.0089	6.54	No	Yes	0	4	5
76	R:R:D292	R:R:S220	21.9495	7.36	No	No	0	5	4
77	R:R:L289	R:R:S220	20.003	6.01	No	No	0	5	4
78	R:R:L270	R:R:Y239	21.4764	5.86	No	Yes	0	8	9
79	R:R:L270	R:R:T266	19.9783	1.47	No	No	0	8	8
80	R:R:R263	R:R:T266	18.5492	10.35	Yes	No	0	7	8
81	R:R:V273	R:R:Y325	17.1792	6.31	No	Yes	0	8	9
82	R:R:L324	R:R:V273	15.6663	5.96	No	No	0	8	8
83	R:R:L324	R:R:M269	11.0635	1.41	No	No	0	8	8
84	R:R:I293	R:R:L289	10.1222	2.85	No	No	0	4	5
85	L:L:K4	R:R:I192	22.9007	4.36	Yes	No	1	0	2
86	L:L:R33	R:R:V291	34.7526	10.46	Yes	No	2	0	4
87	L:L:R33	L:L:R35	18.5689	8.53	Yes	Yes	2	0	0
88	L:L:Y36	R:R:Q130	14.6954	3.38	Yes	No	0	0	6
89	R:R:L92	R:R:N321	35.2011	4.12	No	No	0	9	9
90	R:R:L183	R:R:Y219	15.3755	7.03	No	Yes	0	5	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Y1	R:R:E188	5.61	1	No	Yes	0	4	0	1
L:L:Y1	R:R:K206	5.97	1	No	No	0	3	0	1
L:L:K4	R:R:I192	4.36	1	Yes	No	0	2	0	1
L:L:K4	R:R:I194	4.36	1	Yes	No	0	1	0	1
L:L:Y21	R:R:L40	5.86	1	No	No	0	7	0	1
L:L:R25	R:R:S43	3.95	0	No	No	0	5	0	1
L:L:R25	R:R:L300	13.36	0	No	No	0	1	0	1
L:L:H26	R:R:V297	4.15	0	No	No	0	6	0	1
L:L:Y27	R:R:I192	9.67	1	No	No	0	2	0	1
L:L:N29	R:R:V297	4.43	2	No	No	0	6	0	1
L:L:N29	R:R:Y303	3.49	2	No	Yes	0	4	0	1
L:L:I31	R:R:I192	4.42	1	Yes	No	0	2	0	1
L:L:I31	R:R:A202	3.25	1	Yes	No	0	4	0	1
L:L:I31	R:R:T204	4.56	1	Yes	No	0	4	0	1
L:L:T32	R:R:Y110	11.24	0	No	No	0	5	0	1
L:L:R33	R:R:E205	3.49	2	Yes	No	0	4	0	1
L:L:R33	R:R:Q288	3.5	2	Yes	No	0	5	0	1
L:L:R33	R:R:V291	10.46	2	Yes	No	0	4	0	1
L:L:R33	R:R:D292	11.91	2	Yes	No	0	5	0	1
L:L:Q34	R:R:T107	7.09	0	Yes	No	0	6	0	1
L:L:Q34	R:R:Y110	12.4	0	Yes	No	0	5	0	1
L:L:Q34	R:R:T111	4.25	0	Yes	No	0	4	0	1
L:L:Q34	R:R:F307	4.68	0	Yes	No	0	4	0	1
L:L:R35	R:R:Y219	11.32	2	Yes	Yes	0	6	0	1
L:L:R35	R:R:Q288	5.84	2	Yes	No	0	5	0	1
L:L:R35	R:R:D292	7.15	2	Yes	No	0	5	0	1
L:L:Y36	R:R:Q130	3.38	0	Yes	No	0	6	0	1
L:L:Y36	R:R:S223	3.82	0	Yes	No	0	5	0	1
L:L:Y36	R:R:H285	6.53	0	Yes	No	0	7	0	1
R:R:E39	R:R:I41	15.03	0	No	No	3	3	2	1
R:R:H311	R:R:T107	6.85	6	Yes	No	5	6	2	1
R:R:W116	R:R:Y110	9.65	8	Yes	No	8	5	2	1
R:R:K304	R:R:T111	3	0	No	No	4	4	2	1
R:R:P127	R:R:Q130	4.74	0	Yes	No	5	6	2	1
R:R:L183	R:R:P127	6.57	0	No	Yes	5	5	2	2
R:R:L183	R:R:Y219	7.03	0	No	Yes	5	6	2	1
R:R:E188	R:R:T204	4.23	1	Yes	No	4	4	1	1
R:R:E188	R:R:K206	13.5	1	Yes	No	4	3	1	1
R:R:I194	R:R:P196	3.39	1	No	No	1	3	1	2
R:R:F198	R:R:I194	7.54	1	No	No	1	1	2	1
R:R:F198	R:R:P196	8.67	1	No	No	1	3	2	2
R:R:A202	R:R:T204	3.36	1	No	No	4	4	1	1
R:R:E205	R:R:W207	6.54	0	No	Yes	4	5	1	2
R:R:W207	R:R:Y219	3.86	4	Yes	Yes	5	6	2	1
R:R:D292	R:R:S220	7.36	2	No	No	5	4	1	2
R:R:H285	R:R:W281	5.29	0	No	Yes	7	8	1	2
R:R:F287	R:R:V291	5.24	2	Yes	No	4	4	2	1
R:R:F287	R:R:Y303	9.28	2	Yes	Yes	4	4	2	1
R:R:F287	R:R:F307	4.29	2	Yes	No	4	4	2	1
R:R:F307	R:R:Q288	4.68	0	No	No	4	5	1	1
R:R:V291	R:R:Y303	6.31	2	No	Yes	4	4	1	1
R:R:V297	R:R:Y303	5.05	2	No	Yes	6	4	1	1
L:L:L24	R:R:I41	2.85	1	Yes	No	0	3	0	1
L:L:N29	R:R:L300	2.75	2	No	No	0	1	0	1
L:L:L30	R:R:E205	2.65	0	No	No	0	4	0	1
R:R:K301	R:R:S43	1.53	0	No	No	3	5	2	1
R:R:G216	R:R:Y219	1.45	0	No	Yes	4	6	2	1
R:R:E188	R:R:S190	1.44	1	Yes	No	4	1	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8K6N_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.98
Number of Linked Nodes	307
Number of Links	328
Number of Hubs	33
Number of Links mediated by Hubs	132
Number of Communities	11
Number of Nodes involved in Communities	58
Number of Links involved in Communities	69

Path Summary
Number Of Nodes in MetaPath	91
Number Of Links MetaPath	90
Number of Shortest Paths	49431
Length Of Smallest Path	3
Average Path Length	15.6039
Length of Longest Path	35
Minimum Path Strength	1.26
Average Path Strength	5.78369
Maximum Path Strength	13.87
Minimum Path Correlation	0.7
Average Path Correlation	0.942192
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.57143
Average % Of Corr. Nodes	57.4346
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	32.1073
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	L
Protein	Neuropeptide-Y
UniProt	P01303
Sequence	>8K6N_nogp_Chain_L Y P S K P D N P G E D M A R Y Y S A L R H Y I N L I T R Q R Y Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P49146
Sequence	>8K6N_nogp_Chain_R E L I D S T K L I E V Q V V L I L A Y C S I I L L G V I G N S L V I H V V I K F K S M R T V T N F F I A N L A V A D L L V N T L C L P F T L T Y T L M G E W K M G P V L C H L V P Y A Q G L A V Q V S T I T L T V I A L D R H R C I V Y H L E S K I S K R I S F L I I G L A W G I S A L L A S P L A I F R E Y S L I E I I P D F E I V A C T E K W P G E E K S I Y G T V Y S L S S L L I L Y V L P L G I I S F S Y T R I W S K L K N H V S P G A A N D H Y H Q R R Q K T T K M L V C V V V V F A V S W L P L H A F Q L A V D I D S Q V L D L K E Y K L I F T V F H I I A M C S T F A N P L L Y G W M N S N Y R K A F L S A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	4MQT	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Iperoxo	LY2119620	-	3.7	2013-11-27	doi.org/10.1038/nature12735
	6DS0	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	LY266097	-	-	3.19	2018-08-29	doi.org/10.1038/s41594-018-0116-7
	6OIK	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Iperoxo	LY2119620	chim(NtGi1-Go)/β1/γ2	3.6	2019-05-08	doi.org/10.1126/science.aaw5188
	6OIK (No Gprot)	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Iperoxo	LY2119620		3.6	2019-05-08	doi.org/10.1126/science.aaw5188
	6U1N	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	-	LY2119620	Arrestin2	4	2020-02-26	doi.org/10.1038/s41586-020-1954-0
	7DDZ	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	JNJ-31020028	-	-	2.8	2021-01-27	doi.org/10.1038/s41467-021-21030-9
	7WIH	C	Aminoacid	Metabotropic Glutamate	mGlu3; mGlu3	Homo sapiens	LY2794193	-	-	3.68	2022-03-16	doi.org/10.1038/s41422-022-00623-z
	7TYH	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin	-	Gs/β1/γ2; RAMP2	3.3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYH (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin	-		3.3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYY	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-	Gs/β1/γ2; RAMP2	3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYY (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-		3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYX	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Amylin	-	Gs/β1/γ2; RAMP2	2.55	2022-03-30	doi.org/10.1126/science.abm9609
	7TYX (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Amylin	-		2.55	2022-03-30	doi.org/10.1126/science.abm9609
	7V68	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	LY2119620	Gi1/β1/γ2	3.4	2022-05-11	doi.org/10.1038/s41467-022-30595-y
	7V68 (No Gprot)	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	LY2119620		3.4	2022-05-11	doi.org/10.1038/s41467-022-30595-y
	7X9B	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide-Y	-	Gi1/β1/γ2	3.4	2022-05-18	doi.org/10.1126/sciadv.abm1232
	7X9B (No Gprot)	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide-Y	-		3.4	2022-05-18	doi.org/10.1126/sciadv.abm1232
	7Y24	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-	Go/β1/γ2	3.25	2022-10-19	doi.org/10.1038/s41589-022-01130-3
	7Y24 (No Gprot)	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-		3.25	2022-10-19	doi.org/10.1038/s41589-022-01130-3
	7Y26	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.3	2022-10-19	doi.org/10.1038/s41589-022-01130-3
	7Y26 (No Gprot)	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-		3.3	2022-10-19	doi.org/10.1038/s41589-022-01130-3
	7Y27	A	Peptide	Somatostatin	SST2	Homo sapiens	Somatostatin-14	-	chim(NtGi2L-Gs-CtGq)/β1/γ2	3.48	2022-10-19	doi.org/10.1038/s41589-022-01130-3
	7Y27 (No Gprot)	A	Peptide	Somatostatin	SST2	Homo sapiens	Somatostatin-14	-		3.48	2022-10-19	doi.org/10.1038/s41589-022-01130-3
	7T94	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Acetylcholine	LY2119620	chim(NtGi1-Go)/β1/γ2	3.16	2023-01-25	doi.org/10.1038/s41467-022-35726-z
	7T94 (No Gprot)	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Acetylcholine	LY2119620		3.16	2023-01-25	doi.org/10.1038/s41467-022-35726-z
	7YON	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Peptide-YY(3-36)	-	Gi1/β1/γ2	2.95	2023-03-22	doi.org/10.1016/j.str.2022.11.010
	7YON (No Gprot)	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Peptide-YY(3-36)	-		2.95	2023-03-22	doi.org/10.1016/j.str.2022.11.010
	7YOO	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide-Y	-	Gi1/β1/γ2	3.11	2023-03-22	doi.org/10.1016/j.str.2022.11.010
	7YOO (No Gprot)	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide-Y	-		3.11	2023-03-22	doi.org/10.1016/j.str.2022.11.010
	7TRP	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	LY2033298	Gi1/β1/γ2	2.4	2023-05-17	doi.org/10.2139/ssrn.4034884
	7TRP (No Gprot)	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	LY2033298		2.4	2023-05-17	doi.org/10.2139/ssrn.4034884
	8J19	A	Orphan	Orphan	GPR84	Homo sapiens	LY237	-	Gi1/β1/γ2	3.23	2023-06-21	doi.org/10.1038/s41467-023-38985-6
	8J19 (No Gprot)	A	Orphan	Orphan	GPR84	Homo sapiens	LY237	-		3.23	2023-06-21	doi.org/10.1038/s41467-023-38985-6
	8K6N	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide-Y	-	Gi2/β1/γ1	3.2	2024-07-31	doi.org/10.1002/mco2.565
	8K6N (No Gprot)	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide-Y	-		3.2	2024-07-31	doi.org/10.1002/mco2.565
	7T96	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Acetylcholine	LY2119620	Go/β1/γ2	3.22	2023-01-25	doi.org/10.1038/s41467-022-35726-z
	7T96 (No Gprot)	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Acetylcholine	LY2119620		3.22	2023-01-25	doi.org/10.1038/s41467-022-35726-z
	9BQ3	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Cagrilintide	-	Gs/β1/γ2; RAMP2	2.8	2025-04-23	doi.org/10.1038/s41467-025-58680-y
	9BQ3 (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Cagrilintide	-		2.8	2025-04-23	doi.org/10.1038/s41467-025-58680-y
	9PY2	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	3.16	2025-11-12	10.1038/s41586-025-09677-6
	9PY2 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		3.16	2025-11-12	10.1038/s41586-025-09677-6

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8K6N_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.