psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I71	R:R:T70	3.04	No	No	0	4	4
2	R:R:I71	R:R:Y128	10.88	No	No	2	4	5
3	R:R:H319	R:R:I71	5.3	Yes	No	2	4	4
4	R:R:M72	R:R:S76	3.07	No	No	0	5	4
5	R:R:M72	R:R:S125	3.07	No	No	0	5	6
6	R:R:L129	R:R:M72	4.24	No	No	0	5	5
7	R:R:L74	R:R:Y75	3.52	No	Yes	0	5	7
8	R:R:A323	R:R:L74	4.73	No	No	0	4	5
9	R:R:L121	R:R:Y75	3.52	Yes	Yes	0	7	7
10	R:R:H319	R:R:Y75	7.62	Yes	Yes	0	4	7
11	R:R:I322	R:R:Y75	3.63	No	Yes	0	5	7
12	R:R:I77	R:R:S76	3.1	No	No	0	5	4
13	R:R:C330	R:R:V78	3.42	No	No	0	7	7
14	R:R:C79	R:R:L83	3.17	No	No	0	6	6
15	R:R:C79	R:R:L121	6.35	No	Yes	0	6	7
16	R:R:C79	R:R:P122	5.65	No	No	0	6	8
17	R:R:F87	R:R:L83	7.31	No	No	0	4	6
18	R:R:D114	R:R:N86	4.04	Yes	No	0	9	9
19	R:R:A115	R:R:N86	4.69	No	No	0	7	9
20	R:R:N86	R:R:P333	4.89	No	No	0	9	9
21	R:R:F87	R:R:Y91	12.38	No	No	0	4	4
22	R:R:A337	R:R:V89	3.39	No	No	0	7	9
23	R:R:F108	R:R:M90	4.98	No	No	0	6	7
24	R:R:F347	R:R:V92	6.55	No	No	0	6	7
25	R:R:I93	R:R:T97	9.12	No	No	0	7	6
26	R:R:F343	R:R:I93	3.77	No	No	0	9	7
27	R:R:R95	R:R:Y96	4.12	No	No	0	4	5
28	R:R:C346	R:R:Y96	4.03	No	No	0	5	5
29	R:R:N104	R:R:T97	8.77	No	No	0	8	6
30	R:R:K100	R:R:K98	7.18	No	No	0	6	5
31	R:R:F108	R:R:M99	11.2	No	No	0	6	7
32	R:R:T101	R:R:T103	3.14	No	No	5	8	8
33	R:R:N104	R:R:T101	8.77	No	No	5	8	8
34	R:R:N104	R:R:T103	4.39	No	No	5	8	8
35	R:R:I105	R:R:N188	4.25	No	No	0	6	7
36	R:R:T160	R:R:Y106	7.49	No	Yes	0	7	7
37	R:R:M161	R:R:Y106	3.59	No	Yes	0	8	7
38	R:R:D164	R:R:Y106	5.75	No	Yes	0	8	7
39	R:R:A184	R:R:Y106	4	No	Yes	0	7	7
40	R:R:N188	R:R:Y106	6.98	No	Yes	0	7	7
41	R:R:N109	R:R:N188	12.26	No	No	0	9	7
42	R:R:N109	R:R:W192	11.3	No	Yes	0	9	9
43	R:R:D114	R:R:L110	5.43	Yes	Yes	3	9	9
44	R:R:L110	R:R:T157	8.84	Yes	No	0	9	7
45	R:R:L110	R:R:L158	4.15	Yes	No	3	9	8
46	R:R:L110	R:R:N332	4.12	Yes	No	3	9	9
47	R:R:L110	R:R:Y336	3.52	Yes	Yes	3	9	9
48	R:R:D114	R:R:S154	5.89	Yes	No	0	9	9
49	R:R:D114	R:R:S329	8.83	Yes	No	0	9	9
50	R:R:D114	R:R:N332	12.12	Yes	No	3	9	9
51	R:R:L116	R:R:N150	8.24	No	Yes	0	7	8
52	R:R:L121	R:R:Y326	3.52	Yes	Yes	0	7	7
53	R:R:F123	R:R:W133	5.01	No	Yes	1	6	8
54	R:R:F123	R:R:F135	8.57	No	Yes	1	6	7
55	R:R:Q124	R:R:Y326	4.51	No	Yes	1	6	7
56	L:L:?1	R:R:Q124	18.57	Yes	No	1	0	6
57	R:R:F135	R:R:V126	5.24	Yes	No	0	7	5
58	R:R:N127	R:R:W133	3.39	No	Yes	0	6	8
59	L:L:?1	R:R:N127	7.18	Yes	No	0	0	6
60	R:R:H319	R:R:Y128	4.36	Yes	No	2	4	5
61	R:R:M130	R:R:P134	5.03	No	No	0	3	4
62	R:R:P134	R:R:T132	5.25	No	No	0	4	5
63	R:R:S214	R:R:T132	6.4	No	No	0	2	5
64	R:R:F135	R:R:W133	10.02	Yes	Yes	1	7	8
65	R:R:C140	R:R:W133	3.92	No	Yes	1	9	8
66	R:R:C217	R:R:W133	7.84	Yes	Yes	1	9	8
67	R:R:F135	R:R:P134	5.78	Yes	No	0	7	4
68	R:R:F135	R:R:L139	6.09	Yes	No	0	7	6
69	R:R:N137	R:R:T208	7.31	No	No	0	1	5
70	R:R:C140	R:R:I144	3.27	No	No	1	9	5
71	R:R:C140	R:R:C217	5.46	No	Yes	1	9	9
72	R:R:A206	R:R:K141	4.82	No	No	0	4	6
73	R:R:I144	R:R:V202	3.07	No	No	0	5	5
74	R:R:C217	R:R:I144	3.27	Yes	No	1	9	5
75	R:R:M203	R:R:S145	9.2	No	No	0	4	6
76	R:R:D147	R:R:Y326	4.6	No	Yes	1	6	7
77	L:L:?1	R:R:D147	20.12	Yes	No	1	0	6
78	R:R:V202	R:R:Y148	6.31	No	No	0	5	4
79	L:L:?1	R:R:Y148	7.16	Yes	No	0	0	4
80	R:R:N150	R:R:Y149	3.49	Yes	Yes	0	8	4
81	R:R:T153	R:R:Y149	4.99	No	Yes	4	7	4
82	R:R:W192	R:R:Y149	9.65	Yes	Yes	4	9	4
83	R:R:S195	R:R:Y149	5.09	No	Yes	4	8	4
84	R:R:S196	R:R:Y149	5.09	No	Yes	0	3	4
85	R:R:G199	R:R:Y149	4.35	No	Yes	0	7	4
86	R:R:F152	R:R:M151	6.22	Yes	No	0	7	7
87	R:R:M151	R:R:W293	3.49	No	Yes	0	7	8
88	L:L:?1	R:R:M151	9.86	Yes	No	0	0	7
89	R:R:F152	R:R:F156	4.29	Yes	No	0	7	6
90	R:R:F152	R:R:I198	5.02	Yes	No	0	7	4
91	R:R:F152	R:R:V236	5.24	Yes	No	0	7	5
92	R:R:T153	R:R:W192	15.77	No	Yes	4	7	9
93	R:R:S195	R:R:T153	6.4	No	No	4	8	7
94	R:R:I155	R:R:P244	3.39	No	No	0	8	9
95	R:R:I155	R:R:W293	3.52	No	Yes	0	8	8
96	R:R:F156	R:R:N191	4.83	No	No	0	6	7
97	R:R:L158	R:R:Y336	7.03	No	Yes	3	8	9
98	R:R:C159	R:R:P244	3.77	No	No	0	7	9
99	R:R:T160	R:R:V187	3.17	No	No	0	7	5
100	R:R:M161	R:R:Y336	9.58	No	Yes	0	8	9
101	R:R:S162	R:R:V163	3.23	Yes	No	0	9	6
102	R:R:I248	R:R:S162	6.19	No	Yes	0	8	9
103	R:R:C251	R:R:S162	3.44	No	Yes	0	7	9
104	R:R:S162	R:R:Y252	5.09	Yes	Yes	0	9	9
105	R:R:I167	R:R:V163	3.07	No	No	0	5	6
106	R:R:D164	R:R:R179	13.1	No	No	0	8	6
107	R:R:R165	R:R:Y252	6.17	No	Yes	0	9	9
108	R:R:R165	R:R:Y336	4.12	No	Yes	0	9	9
109	R:R:C170	R:R:Y166	8.06	No	Yes	0	7	8
110	R:R:H171	R:R:Y166	5.44	No	Yes	0	6	8
111	R:R:C251	R:R:Y166	5.38	No	Yes	0	7	8
112	R:R:L254	R:R:Y166	5.86	No	Yes	0	4	8
113	R:R:A168	R:R:R179	6.91	No	No	0	8	6
114	R:R:M255	R:R:V169	7.61	No	No	0	8	8
115	R:R:D177	R:R:K174	9.68	No	No	0	4	4
116	R:R:F178	R:R:K174	17.37	No	No	0	4	4
117	R:R:P181	R:R:T180	3.5	No	No	0	1	7
118	R:R:N183	R:R:T180	5.85	No	No	0	4	7
119	R:R:L219	R:R:V202	4.47	No	No	0	5	5
120	R:R:F221	R:R:M205	7.46	No	No	0	5	4
121	R:R:T207	R:R:T220	6.28	No	No	0	5	4
122	R:R:I215	R:R:T208	6.08	No	No	0	4	5
123	R:R:K209	R:R:Y210	16.72	No	No	0	3	1
124	R:R:D216	R:R:R211	13.1	No	No	0	4	3
125	L:L:?1	R:R:C217	5.54	Yes	Yes	1	0	9
126	R:R:F221	R:R:L219	3.65	No	No	0	5	5
127	R:R:F221	R:R:W228	6.01	No	Yes	0	5	3
128	R:R:S222	R:R:W228	6.18	No	Yes	0	6	3
129	R:R:H223	R:R:P224	6.1	No	No	0	4	1
130	R:R:P224	R:R:W228	8.11	No	Yes	0	1	3
131	R:R:E229	R:R:W226	3.27	No	No	0	4	2
132	R:R:W228	R:R:Y227	10.61	Yes	No	0	3	3
133	R:R:E229	R:R:N230	3.94	No	No	0	4	3
134	R:R:E229	R:R:K233	5.4	No	No	0	4	4
135	R:R:C235	R:R:L231	3.17	No	No	0	3	4
136	R:R:K233	R:R:V300	3.04	No	No	0	4	5
137	R:R:A304	R:R:K233	4.82	No	No	0	4	4
138	L:L:?1	R:R:V236	9.09	Yes	No	0	0	5
139	R:R:F237	R:R:F241	4.29	Yes	No	6	5	8
140	R:R:F237	R:R:I242	3.77	Yes	No	0	5	5
141	R:R:F237	R:R:H297	4.53	Yes	No	6	5	8
142	R:R:F239	R:R:I238	3.77	No	No	0	4	4
143	R:R:F241	R:R:T294	7.78	No	Yes	0	8	5
144	R:R:F241	R:R:H297	7.92	No	No	6	8	8
145	R:R:M243	R:R:P244	3.35	No	No	0	5	9
146	R:R:I290	R:R:V245	4.61	No	No	0	5	6
147	R:R:F289	R:R:I248	3.77	No	No	0	9	8
148	R:R:M255	R:R:Y252	3.59	No	Yes	0	8	9
149	R:R:V282	R:R:Y252	7.57	No	Yes	0	7	9
150	R:R:K271	R:R:S268	7.65	No	No	0	4	4
151	R:R:D272	R:R:K269	4.15	No	No	0	3	1
152	R:R:E270	R:R:R273	11.63	No	No	0	2	4
153	R:R:N274	R:R:R273	3.62	No	No	0	5	4
154	R:R:N274	R:R:R277	6.03	No	No	0	5	7
155	R:R:E341	R:R:R277	9.3	No	No	0	4	7
156	R:R:L335	R:R:V288	4.47	No	No	0	8	6
157	R:R:F289	R:R:W293	5.01	No	Yes	0	9	8
158	R:R:I290	R:R:T294	3.04	No	Yes	0	5	5
159	R:R:C292	R:R:T327	3.38	No	No	0	8	5
160	R:R:C292	R:R:N328	4.72	No	No	0	8	9
161	R:R:H297	R:R:W293	3.17	No	Yes	0	8	8
162	R:R:N328	R:R:W293	6.78	No	Yes	0	9	8
163	R:R:P295	R:R:T294	5.25	No	Yes	0	9	5
164	R:R:I298	R:R:T294	3.04	No	Yes	0	6	5
165	L:L:?1	R:R:I296	3.73	Yes	No	0	0	6
166	R:R:K303	R:R:Y299	3.58	No	Yes	2	4	4
167	R:R:Q314	R:R:Y299	5.64	Yes	Yes	0	4	4
168	R:R:W318	R:R:Y299	4.82	Yes	Yes	2	5	4
169	L:L:?1	R:R:V300	6.5	Yes	No	0	0	5
170	R:R:K303	R:R:W318	6.96	No	Yes	2	4	5
171	R:R:I308	R:R:Q314	12.35	No	Yes	0	1	4
172	R:R:E310	R:R:Q314	20.39	No	Yes	0	1	4
173	R:R:E310	R:R:T315	7.06	No	No	0	1	4
174	R:R:F313	R:R:S317	7.93	No	No	0	2	5
175	R:R:H319	R:R:T315	4.11	Yes	No	0	4	4
176	R:R:H319	R:R:W318	4.23	Yes	Yes	2	4	5
177	R:R:I322	R:R:W318	9.4	No	Yes	0	5	5
178	L:L:?1	R:R:Y326	3.07	Yes	Yes	1	0	7
179	R:R:L331	R:R:T327	4.42	No	No	0	7	5
180	R:R:N328	R:R:N332	10.9	No	No	0	9	9
181	R:R:F338	R:R:V334	3.93	No	No	0	6	6
182	R:R:A337	R:R:F343	4.16	No	No	0	7	9
183	R:R:D340	R:R:N342	9.42	No	No	0	8	6
184	R:R:E341	R:R:K344	6.75	No	No	0	4	8
185	R:R:E341	R:R:R345	5.82	No	No	0	4	4
186	R:R:N342	R:R:R345	9.64	No	No	0	6	4
187	R:R:F84	R:R:G85	3.01	No	No	0	4	7
188	R:R:L121	R:R:V78	2.98	Yes	No	0	7	7
189	R:R:L88	R:R:V92	2.98	No	No	0	6	7
190	R:R:L259	R:R:V169	2.98	Yes	No	0	8	8
191	R:R:L232	R:R:V236	2.98	No	No	0	5	5
192	R:R:I93	R:R:M99	2.92	No	No	0	7	7
193	R:R:I247	R:R:M243	2.92	No	No	0	7	5
194	R:R:I105	R:R:K185	2.91	No	No	0	6	2
195	R:R:I138	R:R:L139	2.85	No	No	0	2	6
196	R:R:I142	R:R:L139	2.85	No	No	0	5	6
197	R:R:I306	R:R:L305	2.85	No	No	0	3	5
198	R:R:L112	R:R:M90	2.83	No	No	0	6	7
199	R:R:I146	R:R:N150	2.83	No	Yes	0	5	8
200	R:R:G325	R:R:W293	2.81	No	Yes	0	7	8
201	R:R:K141	R:R:N137	2.8	No	No	0	6	1
202	R:R:C170	R:R:R258	2.79	No	No	0	7	5
203	R:R:L112	R:R:L116	2.77	No	No	0	6	7
204	R:R:A240	R:R:F152	2.77	No	Yes	0	6	7
205	R:R:A175	R:R:R179	2.77	No	No	0	6	6
206	R:R:A102	R:R:Y106	2.67	No	Yes	0	6	7
207	R:R:R258	R:R:S261	2.64	No	No	0	5	4
208	R:R:F338	R:R:V89	2.62	No	No	0	6	9
209	R:R:F123	R:R:V143	2.62	No	No	0	6	5
210	R:R:A113	R:R:W192	2.59	No	Yes	0	8	9
211	R:R:S125	R:R:Y75	2.54	No	Yes	0	6	7
212	R:R:S317	R:R:Y299	2.54	No	Yes	0	5	4
213	R:R:V286	R:R:Y252	2.52	No	Yes	0	8	9
214	R:R:V285	R:R:Y336	2.52	No	Yes	0	8	9
215	R:R:F237	R:R:I238	2.51	Yes	No	0	5	4
216	R:R:F84	R:R:L88	2.44	No	No	0	4	6
217	R:R:F320	R:R:L324	2.44	No	No	0	5	7
218	R:R:T225	R:R:W226	2.43	No	No	0	3	2
219	R:R:D272	R:R:R276	2.38	No	No	0	3	5
220	R:R:I215	R:R:W133	2.35	No	Yes	0	4	8
221	R:R:F347	R:R:Y96	2.06	No	No	0	6	5
222	R:R:C330	R:R:G82	1.96	No	No	0	7	8
223	R:R:C321	R:R:P295	1.88	No	No	0	6	9
224	R:R:G213	R:R:S214	1.86	No	No	0	3	2
225	R:R:G267	R:R:S266	1.86	No	No	0	3	5
226	R:R:G267	R:R:S268	1.86	No	No	0	3	4
227	R:R:G82	R:R:V81	1.84	No	No	0	8	5
228	R:R:G82	R:R:T118	1.82	No	No	0	8	6
229	R:R:G131	R:R:T132	1.82	No	No	0	4	5
230	R:R:P309	R:R:T307	1.75	No	No	0	3	3
231	R:R:A73	R:R:S76	1.71	No	No	0	5	4
232	R:R:C292	R:R:V288	1.71	No	No	0	8	6
233	R:R:A111	R:R:V89	1.7	No	No	0	9	9
234	R:R:I105	R:R:P181	1.69	No	No	0	6	1
235	R:R:I308	R:R:P309	1.69	No	No	0	1	3
236	R:R:M205	R:R:P201	1.68	No	No	0	4	7
237	R:R:L200	R:R:P201	1.64	No	No	0	3	7
238	R:R:G213	R:R:Q212	1.64	No	No	0	3	5
239	R:R:L324	R:R:P295	1.64	No	No	0	7	9
240	R:R:A337	R:R:I107	1.62	No	No	0	7	8
241	R:R:V80	R:R:V81	1.6	No	No	0	5	5
242	R:R:S119	R:R:T120	1.6	No	No	0	5	6
243	R:R:V284	R:R:V288	1.6	No	No	0	6	6
244	R:R:T70	R:R:V66	1.59	No	No	0	4	2
245	R:R:T120	R:R:V143	1.59	No	No	0	6	5
246	R:R:T249	R:R:V245	1.59	No	No	0	4	6
247	R:R:T249	R:R:V286	1.59	No	No	0	4	8
248	R:R:A68	R:R:L129	1.58	No	No	0	4	5
249	R:R:T67	R:R:T70	1.57	No	No	0	3	4
250	R:R:A117	R:R:N150	1.56	No	Yes	0	7	8
251	R:R:I193	R:R:V189	1.54	No	No	0	4	4
252	R:R:I256	R:R:V282	1.54	No	No	0	5	7
253	R:R:H171	R:R:P172	1.53	No	No	0	6	7
254	R:R:K269	R:R:S268	1.53	No	No	0	1	4
255	R:R:I256	R:R:T279	1.52	No	No	0	5	6
256	R:R:M264	R:R:V262	1.52	No	No	0	5	6
257	R:R:L254	R:R:V250	1.49	No	No	0	4	4
258	R:R:L259	R:R:V262	1.49	Yes	No	0	8	6
259	R:R:I234	R:R:I238	1.47	No	No	0	4	4
260	R:R:I256	R:R:I278	1.47	No	No	0	5	7
261	R:R:L283	R:R:T279	1.47	No	No	0	4	6
262	R:R:I298	R:R:I302	1.47	No	No	0	6	5
263	R:R:I186	R:R:N183	1.42	No	No	0	3	4
264	R:R:Q314	R:R:T311	1.42	Yes	No	0	4	1
265	R:R:K260	R:R:L275	1.41	No	No	0	4	6
266	R:R:L339	R:R:M281	1.41	No	No	0	6	8
267	R:R:D340	R:R:I107	1.4	No	No	0	8	8
268	R:R:L259	R:R:L265	1.38	Yes	No	7	8	3
269	R:R:L259	R:R:L275	1.38	Yes	No	7	8	6
270	R:R:L265	R:R:L275	1.38	No	No	7	3	6
271	R:R:F343	R:R:V92	1.31	No	No	0	9	7
272	R:R:H171	R:R:K174	1.31	No	No	0	6	4
273	R:R:R280	R:R:V284	1.31	No	No	0	6	6
274	R:R:R182	R:R:T180	1.29	No	No	0	3	7
275	R:R:R211	R:R:T218	1.29	No	No	0	3	3
276	R:R:F204	R:R:M205	1.24	No	No	0	5	4
277	R:R:I215	R:R:Y210	1.21	No	No	0	4	1

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y75	4.166	5	0	7
2	R:R:Y106	5.08	6	0	7
3	R:R:L110	5.212	5	3	9
4	R:R:D114	7.262	5	3	9
5	R:R:L121	4.0925	4	0	7
6	R:R:W133	5.42167	6	1	8
7	R:R:F135	7.14	5	1	7
8	R:R:Y149	5.44333	6	4	4
9	R:R:N150	4.03	4	0	8
10	R:R:F152	4.708	5	0	7
11	R:R:S162	4.4875	4	0	9
12	R:R:Y166	6.185	4	0	8
13	R:R:W192	9.8275	4	4	9
14	R:R:C217	5.5275	4	1	9
15	R:R:W228	7.7275	4	0	3
16	R:R:F237	3.775	4	6	5
17	R:R:Y252	4.988	5	0	9
18	R:R:L259	1.8075	4	7	8
19	R:R:W293	4.13	6	0	8
20	R:R:T294	4.7775	4	0	5
21	R:R:Y299	4.145	4	2	4
22	R:R:Q314	9.95	4	0	4
23	R:R:W318	6.3525	4	2	5
24	R:R:H319	5.124	5	2	4
25	R:R:Y326	3.925	4	1	7
26	R:R:Y336	5.354	5	3	9
27	L:L:?1	9.082	10	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:H319	R:R:Y75	28.496	7.62	Yes	Yes	0	4	7
2	R:R:L121	R:R:Y75	52.3998	3.52	Yes	Yes	0	7	7
3	R:R:I322	R:R:Y75	13.5098	3.63	No	Yes	0	5	7
4	R:R:I322	R:R:W318	12.3	9.4	No	Yes	0	5	5
5	R:R:H319	R:R:W318	12.6457	4.23	Yes	Yes	2	4	5
6	R:R:N328	R:R:N332	66.2157	10.9	No	No	0	9	9
7	R:R:N328	R:R:W293	70.4424	6.78	No	Yes	0	9	8
8	R:R:M151	R:R:W293	100	3.49	No	Yes	0	7	8
9	L:L:?1	R:R:M151	98.2372	9.86	Yes	No	0	0	7
10	L:L:?1	R:R:Y326	63.7814	3.07	Yes	Yes	1	0	7
11	R:R:L121	R:R:Y326	63.5098	3.52	Yes	Yes	0	7	7
12	R:R:A337	R:R:F343	20.2992	4.16	No	No	0	7	9
13	R:R:F343	R:R:I93	31.35	3.77	No	No	0	9	7
14	R:R:I93	R:R:M99	37.2309	2.92	No	No	0	7	7
15	R:R:F108	R:R:M99	38.3765	11.2	No	No	0	6	7
16	R:R:F108	R:R:M90	39.5121	4.98	No	No	0	6	7
17	R:R:L112	R:R:M90	40.638	2.83	No	No	0	6	7
18	R:R:L112	R:R:L116	41.7539	2.77	No	No	0	6	7
19	R:R:L116	R:R:N150	42.86	8.24	No	Yes	0	7	8
20	R:R:N150	R:R:Y149	46.1189	3.49	Yes	Yes	0	8	4
21	R:R:W192	R:R:Y149	50.1234	9.65	Yes	Yes	4	9	4
22	R:R:N109	R:R:W192	54.5971	11.3	No	Yes	0	9	9
23	R:R:N109	R:R:N188	55.5896	12.26	No	No	0	9	7
24	R:R:N188	R:R:Y106	63.174	6.98	No	Yes	0	7	7
25	R:R:M161	R:R:Y106	70.9609	3.59	No	Yes	0	8	7
26	R:R:M161	R:R:Y336	71.7411	9.58	No	Yes	0	8	9
27	R:R:L110	R:R:Y336	61.9248	3.52	Yes	Yes	3	9	9
28	R:R:L110	R:R:N332	60.5915	4.12	Yes	No	3	9	9
29	R:R:F343	R:R:V92	11.1643	1.31	No	No	0	9	7
30	R:R:N127	R:R:W133	26.6739	3.39	No	Yes	0	6	8
31	L:L:?1	R:R:N127	27.5676	7.18	Yes	No	0	0	6
32	R:R:C217	R:R:W133	28.0071	7.84	Yes	Yes	1	9	8
33	L:L:?1	R:R:C217	29.4588	5.54	Yes	Yes	1	0	9
34	R:R:F135	R:R:W133	28.728	10.02	Yes	Yes	1	7	8
35	R:R:F135	R:R:P134	17.139	5.78	Yes	No	0	7	4
36	R:R:P134	R:R:T132	12.2901	5.25	No	No	0	4	5
37	R:R:I215	R:R:W133	17.139	2.35	No	Yes	0	4	8
38	L:L:?1	R:R:Y148	14.5566	7.16	Yes	No	0	0	4
39	R:R:V202	R:R:Y148	13.2678	6.31	No	No	0	5	4
40	R:R:F289	R:R:W293	28.0367	5.01	No	Yes	0	9	8
41	R:R:F289	R:R:I248	27.2961	3.77	No	No	0	9	8
42	R:R:I248	R:R:S162	26.901	6.19	No	Yes	0	8	9
43	R:R:C251	R:R:S162	16.4527	3.44	No	Yes	0	7	9
44	R:R:S162	R:R:Y252	21.5781	5.09	Yes	Yes	0	9	9
45	R:R:R165	R:R:Y252	16.6551	6.17	No	Yes	0	9	9
46	R:R:R165	R:R:Y336	16.8527	4.12	No	Yes	0	9	9
47	R:R:C251	R:R:Y166	15.1244	5.38	No	Yes	0	7	8
48	R:R:M255	R:R:Y252	10.9816	3.59	No	Yes	0	8	9
49	R:R:L219	R:R:V202	15.0948	4.47	No	No	0	5	5
50	R:R:F221	R:R:L219	13.7715	3.65	No	No	0	5	5
51	R:R:H297	R:R:W293	20.3091	3.17	No	Yes	0	8	8
52	R:R:F241	R:R:H297	12.4531	7.92	No	No	6	8	8
53	R:R:F241	R:R:T294	11.5297	7.78	No	Yes	0	8	5
54	R:R:D340	R:R:N342	11.031	9.42	No	No	0	8	6
55	R:R:D340	R:R:I107	12.384	1.4	No	No	0	8	8
56	R:R:A337	R:R:I107	13.732	1.62	No	No	0	7	8
57	R:R:C292	R:R:N328	10.157	4.72	No	No	0	8	9
58	R:R:W318	R:R:Y299	20.0918	4.82	Yes	Yes	2	5	4
59	R:R:Q314	R:R:Y299	12.7099	5.64	Yes	Yes	0	4	4
60	R:R:I308	R:R:Q314	11.4458	12.35	No	Yes	0	1	4

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:L121	R:R:Y326	3.52	0	Yes	Yes	7	7	2	1
R:R:Q124	R:R:Y326	4.51	1	No	Yes	6	7	1	1
L:L:?1	R:R:Q124	18.57	1	Yes	No	0	6	0	1
R:R:N127	R:R:W133	3.39	0	No	Yes	6	8	1	2
L:L:?1	R:R:N127	7.18	1	Yes	No	0	6	0	1
R:R:C140	R:R:W133	3.92	1	No	Yes	9	8	2	2
R:R:C217	R:R:W133	7.84	1	Yes	Yes	9	8	1	2
R:R:C140	R:R:I144	3.27	1	No	No	9	5	2	2
R:R:C140	R:R:C217	5.46	1	No	Yes	9	9	2	1
R:R:I144	R:R:V202	3.07	1	No	No	5	5	2	2
R:R:C217	R:R:I144	3.27	1	Yes	No	9	5	1	2
R:R:D147	R:R:Y326	4.6	1	No	Yes	6	7	1	1
L:L:?1	R:R:D147	20.12	1	Yes	No	0	6	0	1
R:R:V202	R:R:Y148	6.31	0	No	No	5	4	2	1
L:L:?1	R:R:Y148	7.16	1	Yes	No	0	4	0	1
R:R:F152	R:R:M151	6.22	0	Yes	No	7	7	2	1
R:R:M151	R:R:W293	3.49	0	No	Yes	7	8	1	2
L:L:?1	R:R:M151	9.86	1	Yes	No	0	7	0	1
R:R:F152	R:R:V236	5.24	0	Yes	No	7	5	2	1
L:L:?1	R:R:C217	5.54	1	Yes	Yes	0	9	0	1
R:R:K233	R:R:V300	3.04	0	No	No	4	5	2	1
L:L:?1	R:R:V236	9.09	1	Yes	No	0	5	0	1
L:L:?1	R:R:I296	3.73	1	Yes	No	0	6	0	1
L:L:?1	R:R:V300	6.5	1	Yes	No	0	5	0	1
L:L:?1	R:R:Y326	3.07	1	Yes	Yes	0	7	0	1
R:R:L232	R:R:V236	2.98	0	No	No	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7SCG_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.04
Number of Linked Nodes	266
Number of Links	277
Number of Hubs	27
Number of Links mediated by Hubs	115
Number of Communities	7
Number of Nodes involved in Communities	34
Number of Links involved in Communities	41

Path Summary
Number Of Nodes in MetaPath	61
Number Of Links MetaPath	60
Number of Shortest Paths	39664
Length Of Smallest Path	3
Average Path Length	14.545
Length of Longest Path	41
Minimum Path Strength	1.395
Average Path Strength	5.56355
Maximum Path Strength	19.345
Minimum Path Correlation	0.7
Average Path Correlation	0.928785
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.85714
Average % Of Corr. Nodes	48.3356
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.9899
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • G protein-coupled opioid receptor activity • G-protein alpha-subunit binding • peptide receptor activity • beta-endorphin receptor activity • G protein-coupled peptide receptor activity • melanocortin receptor activity • neuropeptide receptor activity • morphine receptor activity • behavior • multicellular organismal process • locomotory behavior • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway • trans-synaptic signaling • regulation of signaling • modulation of chemical synaptic transmission • presynaptic modulation of chemical synaptic transmission • chemical synaptic transmission • regulation of trans-synaptic signaling • anterograde trans-synaptic signaling • regulation of cell communication • positive regulation of cell communication • positive regulation of signal transduction • positive regulation of biological process • regulation of signal transduction • intracellular signal transduction • positive regulation of response to stimulus • positive regulation of ERK1 and ERK2 cascade • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of cellular process • positive regulation of MAPK cascade • positive regulation of intracellular signal transduction • regulation of MAPK cascade • regulation of response to stimulus • MAPK cascade • ERK1 and ERK2 cascade • regulation of ERK1 and ERK2 cascade • positive regulation of signaling • regulation of localization • transport • regulation of signaling receptor activity • regulation of transmembrane transporter activity • regulation of transporter activity • localization • regulation of NMDA receptor activity • regulation of monoatomic ion transmembrane transporter activity • regulation of transport • establishment of localization • transmembrane transport • regulation of molecular function • regulation of transmembrane transport • regulation of neurotransmitter receptor activity • G protein-coupled opioid receptor signaling pathway • regulation of biosynthetic process • regulation of nitric oxide biosynthetic process • negative regulation of metabolic process • negative regulation of biological process • negative regulation of nitric oxide metabolic process • reactive nitrogen species metabolic process • nitric oxide metabolic process • nitric oxide biosynthetic process • biosynthetic process • negative regulation of nitric oxide biosynthetic process • negative regulation of biosynthetic process • negative regulation of cellular process • metabolic process • regulation of nitric oxide metabolic process • regulation of metabolic process • system process • nervous system process • transmission of nerve impulse • phospholipase C-activating G protein-coupled receptor signaling pathway • regulation of biological quality • negative regulation of cytosolic calcium ion concentration • positive regulation of nervous system development • regulation of developmental process • cellular developmental process • cell development • regulation of cell differentiation • regulation of neurogenesis • regulation of cell development • regulation of nervous system development • positive regulation of developmental process • multicellular organism development • neurogenesis • positive regulation of cell differentiation • cell differentiation • anatomical structure development • positive regulation of neurogenesis • regulation of multicellular organismal process • system development • developmental process • regulation of multicellular organismal development • positive regulation of cell development • nervous system development • positive regulation of multicellular organismal process • negative regulation of signaling • negative regulation of intracellular signal transduction • negative regulation of cell communication • cAMP-mediated signaling • negative regulation of response to stimulus • negative regulation of signal transduction • negative regulation of cAMP-mediated signaling • regulation of cAMP-mediated signaling • sensory perception • sensory perception of pain • protein localization • negative regulation of protein transport • establishment of protein localization • nitrogen compound transport • negative regulation of transport • negative regulation of secretion • cellular macromolecule localization • negative regulation of secretion by cell • establishment of protein localization to extracellular region • negative regulation of establishment of protein localization • protein secretion • regulation of protein secretion • regulation of secretion • negative regulation of protein secretion • cellular localization • regulation of protein localization • negative regulation of Wnt protein secretion • protein localization to extracellular region • secretion by cell • regulation of secretion by cell • signal release • regulation of Wnt protein secretion • negative regulation of protein localization • secretion • regulation of establishment of protein localization • export from cell • regulation of protein transport • Wnt protein secretion • protein transport • regulation of cellular localization • macromolecule localization • somatodendritic compartment • cell body • perikaryon • neuronal cell body • presynapse • dendrite • dendritic tree • GABA-ergic synapse • endosome • intracellular vesicle • endomembrane system • cytoplasmic vesicle • axon • D2 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • phosphorus-oxygen lyase activity • enzyme regulator activity • cyclase regulator activity • molecular function regulator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • catalytic activity • adenylate cyclase activity • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • cation binding • magnesium ion binding • metal ion binding • GDP binding • G protein-coupled serotonin receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • response to peptide hormone • cell division • leukocyte migration • immune system process • mononuclear cell migration • lymphocyte migration • cell migration • T cell migration • cell motility • regulation of steroid biosynthetic process • regulation of cholesterol biosynthetic process • regulation of cholesterol metabolic process • steroid metabolic process • regulation of lipid metabolic process • sterol metabolic process • cholesterol metabolic process • lipid biosynthetic process • alcohol metabolic process • regulation of primary metabolic process • positive regulation of metabolic process • regulation of small molecule metabolic process • positive regulation of biosynthetic process • positive regulation of lipid metabolic process • small molecule metabolic process • steroid biosynthetic process • secondary alcohol biosynthetic process • regulation of alcohol biosynthetic process • small molecule biosynthetic process • regulation of steroid metabolic process • cholesterol biosynthetic process • positive regulation of cholesterol biosynthetic process • primary metabolic process • secondary alcohol metabolic process • positive regulation of steroid biosynthetic process • sterol biosynthetic process • positive regulation of lipid biosynthetic process • regulation of sterol biosynthetic process • alcohol biosynthetic process • positive regulation of cholesterol metabolic process • positive regulation of steroid metabolic process • regulation of lipid biosynthetic process • positive regulation of small molecule metabolic process • positive regulation of alcohol biosynthetic process • positive regulation of sterol biosynthetic process • lipid metabolic process • regulation of cytoskeleton organization • regulation of cellular component organization • microtubule cytoskeleton organization • regulation of mitotic spindle organization • mitotic cell cycle • cellular component organization • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • microtubule cytoskeleton organization involved in mitosis • spindle organization • cell cycle process • regulation of cell cycle process • regulation of microtubule-based process • regulation of spindle organization • regulation of organelle organization • mitotic spindle organization • organelle organization • mitotic cell cycle process • microtubule-based process • cytoskeleton organization • regulation of microtubule cytoskeleton organization • positive regulation of protein localization to cell periphery • protein localization to cell periphery • positive regulation of protein localization to cell cortex • regulation of protein localization to cell periphery • regulation of protein localization to cell cortex • positive regulation of protein localization • protein localization to cell cortex • cellular response to forskolin • response to forskolin • midbody • nucleus • membrane-enclosed lumen • intracellular membraneless organelle • nucleolus • intracellular organelle lumen • organelle lumen • membraneless organelle • nuclear lumen • cell cortex • centrosome • microtubule organizing center • cytoskeleton • microtubule cytoskeleton • centriolar satellite • nucleoplasm • Golgi apparatus • ciliary basal body
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	8RI
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	8RI
Name	(2E)-N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-(naphthalen-1-yl)prop-2-enamide
Synonyms
Identifier
Formula	C24 H26 N2 O2
Molecular Weight	374.475
SMILES
PubChem	162745306
Formal Charge	0
Total Atoms	54
Total Chiral Atoms	1
Total Bonds	56
Total Aromatic Bonds	17


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P42866
Sequence	>7SCG_nogp_Chain_R V T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T K M K T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G T W P F G N I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H P V K A L D F R T P R N A K I V N V C N W I L S S A I G L P V M F M A T T K Y R Q G S I D C T L T F S H P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V R M L S G S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L I T I P E T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F K R C F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9MQJ	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.23	2025-02-12	10.1101/2025.01.09.632033
	9MQI	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.3	2025-02-12	10.1101/2025.01.09.632033
	9MQH	A	Peptide	Opioid	μ	Homo sapiens	-	-	-	3.9	2025-02-12	10.1101/2025.01.09.632033
	9BQJ	A	Peptide	Opioid	μ	Mus musculus	RO76	-	Gi1/β1/γ2	3.3	2024-09-11	10.1021/acscentsci.4c00525
	9BQJ (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	RO76	-		3.3	2024-09-11	10.1021/acscentsci.4c00525
	9BJK	A	Peptide	Opioid	μ	Mus musculus	Naloxone	NAM	-	3.26	2024-07-17	10.1038/s41586-024-07587-7
	8K9L	A	Peptide	Opioid	μ	Homo sapiens	Damgo	VV9	Gi3/β1/γ1	3.05	2024-05-29	10.1038/s41467-024-47792-6
	8K9L (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Damgo	VV9		3.05	2024-05-29	10.1038/s41467-024-47792-6
	8K9K	A	Peptide	Opioid	μ	Homo sapiens	Damgo	-	Gi3/β1/γ1	2.98	2024-05-29	10.1038/s41467-024-47792-6
	8K9K (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Damgo	-		2.98	2024-05-29	10.1038/s41467-024-47792-6
	8QOT	A	Peptide	Opioid	μ	Mus musculus	Nanobody-E	-	-	3.2	2023-12-27	10.1101/2023.12.06.570395
	8E0G	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.1	2023-10-18	10.1186/s12915-023-01689-w
	8F7R	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Gi1/β1/γ2	3.28	2022-12-14	10.1016/j.cell.2022.12.026
	8F7R (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		3.28	2022-12-14	10.1016/j.cell.2022.12.026
	8F7Q	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-	Gi1/β1/γ2	3.22	2022-12-14	10.1016/j.cell.2022.12.026
	8F7Q (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-		3.22	2022-12-14	10.1016/j.cell.2022.12.026
	7T2H	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-	Gi1/β1/γ2	2.5	2022-12-07	10.1038/s41589-022-01208-y
	7T2H (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-		2.5	2022-12-07	10.1038/s41589-022-01208-y
	7T2G	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-	Gi1/β1/γ2	2.5	2022-12-07	10.1038/s41589-022-01208-y
	7T2G (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-		2.5	2022-12-07	10.1038/s41589-022-01208-y
	7U2K	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-	Gi1/β1/γ2	3.3	2022-12-07	10.1038/s41586-022-05588-y
	7U2K (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-		3.3	2022-12-07	10.1038/s41586-022-05588-y
	8EFQ	A	Peptide	Opioid	μ	Homo sapiens	Damgo	-	Gi1/β1/γ2	3.3	2022-11-09	10.1016/j.cell.2022.09.041
	8EFQ (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Damgo	-		3.3	2022-11-09	10.1016/j.cell.2022.09.041
	8EFO	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-	Gi1/β1/γ2	2.8	2022-11-09	10.1016/j.cell.2022.09.041
	8EFO (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-		2.8	2022-11-09	10.1016/j.cell.2022.09.041
	8EFL	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-	Gi1/β1/γ2	3.2	2022-11-09	10.1016/j.cell.2022.09.041
	8EFL (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-		3.2	2022-11-09	10.1016/j.cell.2022.09.041
	8EFB	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-	Gi1/β1/γ2	3.2	2022-11-09	10.1016/j.cell.2022.09.041
	8EFB (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-		3.2	2022-11-09	10.1016/j.cell.2022.09.041
	8EF6	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-	Gi1/β1/γ2	3.2	2022-11-09	10.1016/j.cell.2022.09.041
	8EF6 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-		3.2	2022-11-09	10.1016/j.cell.2022.09.041
	8EF5	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-	Gi1/β1/γ2	3.3	2022-11-09	10.1016/j.cell.2022.09.041
	8EF5 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-		3.3	2022-11-09	10.1016/j.cell.2022.09.041
	7UL4	A	Peptide	Opioid	μ	Mus musculus	Alvimopan	-	-	2.8	2022-06-29	10.1038/s41594-022-00859-8
	7U2L	A	Peptide	Opioid	μ	Mus musculus	PubChem 163201242	-	Gi1/β1/γ2	3.2	2022-05-04	10.1038/s41586-022-05588-y
	7U2L (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	PubChem 163201242	-		3.2	2022-05-04	10.1038/s41586-022-05588-y
	7SCG	A	Peptide	Opioid	μ	Mus musculus	FH210	-	Gi1/β1/γ2	3	2022-04-20	10.1002/anie.202200269
	7SCG (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	FH210	-		3	2022-04-20	10.1002/anie.202200269
	7SBF	A	Peptide	Opioid	μ	Mus musculus	PZM21	-	Gi1/β1/γ2	2.9	2022-04-20	10.1002/anie.202200269
	7SBF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	PZM21	-		2.9	2022-04-20	10.1002/anie.202200269
	6DDF	A	Peptide	Opioid	μ	Mus musculus	Damgo	-	Gi1/β1/γ2	3.5	2018-06-13	10.1038/s41586-018-0219-7
	6DDF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Damgo	-		3.5	2018-06-13	10.1038/s41586-018-0219-7
	6DDE	A	Peptide	Opioid	μ	Mus musculus	Damgo	-	Gi1/β1/γ2	3.5	2018-06-13	10.1038/s41586-018-0219-7
	6DDE (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Damgo	-		3.5	2018-06-13	10.1038/s41586-018-0219-7
	5C1M	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.07	2015-08-05	10.1038/nature14886
	4DKL	A	Peptide	Opioid	μ	Mus musculus	β-Funaltrexamine	-	-	2.8	2012-03-21	10.1038/nature10954

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7SCG_nogp.zip

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