psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I71	R:R:M67	4.37	No	No	0	5	2
2	R:R:T314	R:R:T69	4.71	No	No	0	1	4
3	R:R:I73	R:R:Y130	9.67	No	No	5	6	5
4	R:R:I73	R:R:V318	4.61	No	No	0	6	1
5	R:R:H321	R:R:I73	3.98	Yes	No	5	4	6
6	R:R:L131	R:R:M74	11.31	No	No	0	4	5
7	R:R:F322	R:R:L76	4.87	No	No	0	4	5
8	R:R:A325	R:R:L76	4.73	No	No	0	6	5
9	R:R:S127	R:R:Y77	5.09	No	No	0	6	7
10	R:R:H321	R:R:Y77	13.07	Yes	No	0	4	7
11	R:R:I324	R:R:Y77	7.25	No	No	0	5	7
12	R:R:C81	R:R:L123	4.76	No	No	0	6	7
13	R:R:C332	R:R:G84	3.92	No	No	0	8	8
14	R:R:L85	R:R:T120	5.9	No	No	0	6	5
15	R:R:G87	R:R:P335	4.06	No	Yes	0	8	9
16	R:R:D116	R:R:N88	6.73	Yes	No	0	9	9
17	R:R:A117	R:R:N88	4.69	No	No	0	7	9
18	R:R:N88	R:R:P335	4.89	No	Yes	0	9	9
19	R:R:F89	R:R:M92	4.98	No	No	0	4	7
20	R:R:A117	R:R:F89	4.16	No	No	0	7	4
21	R:R:F110	R:R:M92	6.22	No	No	0	6	7
22	R:R:L114	R:R:M92	4.24	No	No	0	7	7
23	R:R:I95	R:R:T99	4.56	No	No	0	7	6
24	R:R:F345	R:R:I95	5.02	Yes	No	0	8	7
25	R:R:F110	R:R:V96	3.93	No	No	0	6	3
26	R:R:R97	R:R:Y98	8.23	No	No	0	5	4
27	R:R:F352	R:R:Y98	15.47	No	No	0	7	4
28	R:R:N106	R:R:T99	7.31	No	No	0	8	6
29	R:R:F110	R:R:M101	4.98	No	No	0	6	7
30	R:R:N106	R:R:T103	7.31	No	No	0	8	7
31	R:R:R181	R:R:T105	7.76	Yes	No	0	7	8
32	R:R:F345	R:R:N106	7.25	Yes	No	0	8	8
33	R:R:A186	R:R:I107	4.87	No	No	0	7	5
34	R:R:I107	R:R:K187	4.36	No	No	0	5	2
35	R:R:D166	R:R:Y108	6.9	No	Yes	0	8	7
36	R:R:A186	R:R:Y108	6.67	No	Yes	0	7	7
37	R:R:N190	R:R:Y108	10.47	No	Yes	0	7	7
38	R:R:I109	R:R:M163	4.37	No	No	0	8	9
39	R:R:F345	R:R:I109	5.02	Yes	No	0	8	8
40	R:R:N111	R:R:N190	13.62	No	No	0	9	7
41	R:R:N111	R:R:W194	6.78	No	Yes	0	9	9
42	R:R:D116	R:R:L112	5.43	Yes	Yes	1	9	9
43	R:R:L112	R:R:T159	5.9	Yes	No	0	9	8
44	R:R:L112	R:R:L160	4.15	Yes	No	1	9	8
45	R:R:L112	R:R:N334	6.87	Yes	Yes	1	9	9
46	R:R:L112	R:R:Y338	5.86	Yes	Yes	1	9	9
47	R:R:L114	R:R:W194	4.56	No	Yes	0	7	9
48	R:R:D116	R:R:S156	7.36	Yes	No	0	9	9
49	R:R:D116	R:R:S331	11.78	Yes	No	0	9	9
50	R:R:D116	R:R:N334	8.08	Yes	Yes	1	9	9
51	R:R:L118	R:R:N152	13.73	No	No	0	7	8
52	R:R:Q126	R:R:T122	5.67	Yes	No	2	6	6
53	R:R:D149	R:R:T122	7.23	Yes	No	2	5	6
54	R:R:L123	R:R:Y328	16.41	No	Yes	0	7	7
55	R:R:F125	R:R:W135	4.01	No	Yes	3	6	8
56	R:R:F125	R:R:F137	12.86	No	Yes	3	6	6
57	R:R:F125	R:R:V145	13.11	No	No	3	6	5
58	R:R:D149	R:R:Q126	5.22	Yes	Yes	2	5	6
59	R:R:Q126	R:R:Y328	10.15	Yes	Yes	2	6	7
60	L:L:?1	R:R:Q126	13.09	Yes	Yes	2	0	6
61	R:R:M132	R:R:V128	4.56	No	No	0	4	3
62	R:R:F137	R:R:V128	7.87	Yes	No	0	6	3
63	R:R:N129	R:R:W135	9.04	No	Yes	0	4	8
64	R:R:H321	R:R:Y130	14.16	Yes	No	5	4	5
65	R:R:M132	R:R:P136	5.03	No	No	0	4	3
66	R:R:I217	R:R:T134	4.56	No	No	0	4	5
67	R:R:F137	R:R:W135	21.05	Yes	Yes	3	6	8
68	R:R:C142	R:R:W135	7.84	No	Yes	3	9	8
69	R:R:V145	R:R:W135	7.36	No	Yes	3	5	8
70	R:R:C219	R:R:W135	20.89	No	Yes	3	9	8
71	R:R:F137	R:R:P136	5.78	Yes	No	0	6	3
72	R:R:F137	R:R:L141	6.09	Yes	No	0	6	5
73	R:R:T139	R:R:T210	10.99	No	No	0	3	4
74	R:R:C142	R:R:C219	7.28	No	No	3	9	9
75	R:R:A208	R:R:I146	6.5	No	No	0	5	4
76	R:R:C219	R:R:I146	4.91	No	No	0	9	4
77	L:L:?1	R:R:I146	7.02	Yes	No	0	0	4
78	R:R:M205	R:R:S147	9.2	No	No	0	5	6
79	R:R:I148	R:R:N152	5.66	No	No	0	5	8
80	R:R:D149	R:R:Y328	8.05	Yes	Yes	2	5	7
81	L:L:?1	R:R:D149	26.7	Yes	Yes	2	0	5
82	R:R:V204	R:R:Y150	8.83	No	No	2	5	4
83	R:R:L221	R:R:Y150	7.03	No	No	2	4	4
84	L:L:?1	R:R:Y150	11.53	Yes	No	2	0	4
85	R:R:N152	R:R:Y151	4.65	No	Yes	0	8	5
86	R:R:T155	R:R:Y151	7.49	Yes	Yes	4	7	5
87	R:R:W194	R:R:Y151	11.58	Yes	Yes	4	9	5
88	R:R:S197	R:R:Y151	3.82	No	Yes	4	8	5
89	R:R:G201	R:R:Y151	4.35	No	Yes	0	6	5
90	R:R:M153	R:R:W295	5.82	No	Yes	0	7	8
91	L:L:?1	R:R:M153	8.11	Yes	No	0	0	7
92	R:R:F154	R:R:F158	4.29	Yes	No	0	6	5
93	R:R:F154	R:R:I200	8.79	Yes	No	0	6	5
94	R:R:F154	R:R:V238	5.24	Yes	No	0	6	5
95	R:R:A242	R:R:F154	4.16	No	Yes	0	5	6
96	R:R:T155	R:R:W194	15.77	Yes	Yes	4	7	9
97	R:R:S197	R:R:T155	6.4	No	Yes	4	8	7
98	R:R:F291	R:R:I157	5.02	Yes	No	1	9	7
99	R:R:I157	R:R:W295	10.57	No	Yes	1	7	8
100	R:R:L160	R:R:N334	6.87	No	Yes	1	8	9
101	R:R:L160	R:R:Y338	8.21	No	Yes	1	8	9
102	R:R:C161	R:R:I249	9.82	No	No	0	7	6
103	R:R:N193	R:R:T162	7.31	No	No	0	7	7
104	R:R:M163	R:R:Y338	7.18	No	Yes	0	9	9
105	R:R:S164	R:R:Y254	10.17	No	Yes	0	9	9
106	R:R:D166	R:R:F180	4.78	No	No	0	8	3
107	R:R:D166	R:R:R181	14.29	No	Yes	0	8	7
108	R:R:R167	R:R:Y254	9.26	No	Yes	0	9	9
109	R:R:C172	R:R:Y168	10.75	No	Yes	0	7	8
110	R:R:H173	R:R:Y168	7.62	No	Yes	0	6	8
111	R:R:C253	R:R:Y168	6.72	No	Yes	0	8	8
112	R:R:L256	R:R:Y168	7.03	No	Yes	0	5	8
113	R:R:F180	R:R:I169	15.07	No	No	0	3	5
114	R:R:A170	R:R:R181	5.53	No	Yes	0	8	7
115	R:R:M257	R:R:V171	4.56	No	No	0	8	8
116	R:R:L261	R:R:V171	4.47	No	No	0	8	8
117	R:R:C172	R:R:R260	4.18	No	No	0	7	5
118	R:R:F180	R:R:N185	4.83	No	No	0	3	4
119	R:R:I189	R:R:N185	7.08	No	No	0	5	4
120	R:R:L202	R:R:S198	6.01	No	No	0	4	4
121	R:R:L221	R:R:V204	4.47	No	No	2	4	5
122	R:R:T209	R:R:T222	7.85	No	No	0	5	4
123	R:R:I217	R:R:Y212	4.84	No	No	0	4	3
124	R:R:D218	R:R:R213	5.96	No	No	0	4	2
125	R:R:D218	R:R:T220	4.34	No	No	0	4	4
126	R:R:E231	R:R:F223	9.33	No	Yes	0	4	6
127	R:R:F223	R:R:L234	4.87	Yes	No	0	6	6
128	R:R:S224	R:R:W230	4.94	No	Yes	0	3	1
129	R:R:H225	R:R:P226	4.58	No	No	0	2	4
130	R:R:P226	R:R:W228	5.4	No	No	0	4	1
131	R:R:P226	R:R:W230	4.05	No	Yes	0	4	1
132	R:R:W228	R:R:Y229	7.72	No	No	0	1	1
133	R:R:W230	R:R:Y229	5.79	Yes	No	6	1	1
134	R:R:L233	R:R:Y229	5.86	No	No	6	3	1
135	R:R:L233	R:R:W230	4.56	No	Yes	6	3	1
136	R:R:E231	R:R:K235	4.05	No	Yes	0	4	4
137	R:R:K235	R:R:V302	4.55	Yes	No	0	4	5
138	R:R:A306	R:R:K235	4.82	No	Yes	0	4	4
139	R:R:C237	R:R:F241	5.59	No	No	0	5	4
140	L:L:?1	R:R:V238	12.21	Yes	No	0	0	5
141	R:R:F239	R:R:I244	11.3	No	No	0	6	4
142	R:R:F239	R:R:H299	4.53	No	Yes	0	6	7
143	R:R:F243	R:R:V247	3.93	No	No	0	8	6
144	R:R:F243	R:R:T296	7.78	No	No	0	8	5
145	R:R:F243	R:R:H299	16.97	No	Yes	0	8	7
146	R:R:F291	R:R:P246	4.33	Yes	No	0	9	8
147	R:R:I250	R:R:V288	4.61	No	No	0	8	8
148	R:R:F291	R:R:I250	8.79	Yes	No	0	9	8
149	R:R:V284	R:R:Y254	8.83	No	Yes	0	8	9
150	R:R:V287	R:R:Y254	3.79	No	Yes	0	8	9
151	R:R:V288	R:R:Y254	3.79	No	Yes	0	8	9
152	R:R:I258	R:R:T281	9.12	No	No	0	5	6
153	R:R:I258	R:R:V284	6.14	No	No	0	5	8
154	R:R:L261	R:R:L267	4.15	No	No	0	8	1
155	R:R:M266	R:R:V264	4.56	No	No	0	4	6
156	R:R:L267	R:R:L277	11.07	No	No	0	1	6
157	R:R:K273	R:R:S270	7.65	No	No	0	3	2
158	R:R:E272	R:R:R275	10.47	No	No	0	3	4
159	R:R:N276	R:R:R279	8.44	No	No	0	5	7
160	R:R:I280	R:R:N276	4.25	No	No	0	8	5
161	R:R:E343	R:R:R279	10.47	No	No	0	5	7
162	R:R:L341	R:R:M283	9.9	No	No	0	7	8
163	R:R:L337	R:R:V287	4.47	No	No	0	8	8
164	R:R:V287	R:R:Y338	5.05	No	Yes	0	8	9
165	R:R:L333	R:R:V290	5.96	No	No	7	6	7
166	R:R:L337	R:R:V290	4.47	No	No	7	8	7
167	R:R:F291	R:R:W295	7.02	Yes	Yes	1	9	8
168	R:R:F291	R:R:N330	4.83	Yes	Yes	1	9	9
169	R:R:C294	R:R:N330	7.87	No	Yes	0	9	9
170	R:R:H299	R:R:W295	8.46	Yes	Yes	0	7	8
171	R:R:G327	R:R:W295	8.44	No	Yes	0	7	8
172	R:R:N330	R:R:W295	7.91	Yes	Yes	1	9	8
173	R:R:Q316	R:R:Y301	5.64	Yes	No	0	3	5
174	R:R:S319	R:R:Y301	7.63	No	No	0	4	5
175	R:R:W320	R:R:Y301	5.79	Yes	No	0	4	5
176	L:L:?1	R:R:V302	10.99	Yes	No	0	0	5
177	R:R:K305	R:R:W320	10.44	No	Yes	0	3	4
178	R:R:I310	R:R:Q316	8.23	No	Yes	0	4	3
179	R:R:H321	R:R:W320	6.35	Yes	Yes	0	4	4
180	R:R:I324	R:R:W320	7.05	No	Yes	0	5	4
181	R:R:F322	R:R:L326	7.31	No	No	0	4	8
182	L:L:?1	R:R:I324	7.02	Yes	No	0	0	5
183	L:L:?1	R:R:Y328	5.77	Yes	Yes	2	0	7
184	R:R:N330	R:R:N334	9.54	Yes	Yes	1	9	9
185	R:R:L333	R:R:V336	5.96	No	No	0	6	6
186	R:R:L333	R:R:L337	4.15	No	No	7	6	8
187	R:R:N334	R:R:Y338	8.14	Yes	Yes	1	9	9
188	R:R:F340	R:R:F349	5.36	No	No	0	6	6
189	R:R:E343	R:R:K346	8.1	No	No	0	5	8
190	R:R:N344	R:R:R347	9.64	No	No	0	7	5
191	R:R:R347	R:R:R350	6.4	No	No	0	5	5
192	R:R:E351	R:R:F352	11.66	No	No	0	3	7
193	R:R:C81	R:R:P124	3.77	No	No	0	6	8
194	R:R:C161	R:R:P246	3.77	No	No	0	7	8
195	R:R:F241	R:R:I240	3.77	No	No	0	4	5
196	R:R:C323	R:R:P297	3.77	No	No	0	6	9
197	R:R:T162	R:R:Y108	3.75	No	Yes	0	7	7
198	R:R:T317	R:R:Y130	3.75	No	No	0	4	5
199	R:R:F223	R:R:M207	3.73	Yes	No	0	6	5
200	R:R:K211	R:R:R213	3.71	No	No	0	1	2
201	R:R:F89	R:R:L85	3.65	No	No	0	4	6
202	R:R:F340	R:R:L90	3.65	No	No	0	6	6
203	R:R:G84	R:R:T120	3.64	No	No	0	8	5
204	R:R:D342	R:R:F345	3.58	No	Yes	0	8	8
205	R:R:P335	R:R:V91	3.53	Yes	No	0	9	9
206	R:R:I217	R:R:W135	3.52	No	Yes	0	4	8
207	R:R:C253	R:R:S164	3.44	No	No	0	8	9
208	R:R:C332	R:R:V80	3.42	No	No	0	8	7
209	R:R:A113	R:R:V91	3.39	No	No	0	9	9
210	R:R:A339	R:R:V91	3.39	No	No	0	6	9
211	R:R:C142	R:R:T210	3.38	No	No	0	9	4
212	R:R:A115	R:R:T155	3.36	No	Yes	0	8	7
213	R:R:D274	R:R:G269	3.35	No	No	0	1	1
214	R:R:C323	R:R:I298	3.27	No	No	0	6	6
215	R:R:S216	R:R:T134	3.2	No	No	0	1	5
216	R:R:M74	R:R:S127	3.07	No	No	0	5	6
217	R:R:I169	R:R:V165	3.07	No	No	0	5	6
218	R:R:I195	R:R:V191	3.07	No	No	0	4	4
219	R:R:I292	R:R:T296	3.04	No	No	0	6	5
220	R:R:I300	R:R:T296	3.04	No	No	0	6	5
221	R:R:F86	R:R:G87	3.01	No	No	0	5	8
222	R:R:F223	R:R:W230	3.01	Yes	Yes	0	6	1
223	R:R:L256	R:R:V252	2.98	No	No	0	5	4
224	R:R:L277	R:R:T281	2.95	No	No	0	6	6
225	R:R:I144	R:R:I148	2.94	No	No	0	5	5
226	R:R:I236	R:R:I240	2.94	No	No	0	4	5
227	R:R:I300	R:R:I304	2.94	No	No	0	6	5
228	R:R:I240	R:R:M245	2.92	No	No	0	5	5
229	R:R:I244	R:R:M245	2.92	No	No	0	4	5
230	R:R:F340	R:R:P335	2.89	No	Yes	0	6	9
231	R:R:I280	R:R:L267	2.85	No	No	0	8	1
232	R:R:I303	R:R:L307	2.85	No	No	0	5	5
233	R:R:L248	R:R:M245	2.83	No	No	0	3	5
234	R:R:Q316	R:R:T313	2.83	Yes	No	0	3	3
235	R:R:K235	R:R:N232	2.8	Yes	No	0	4	2
236	R:R:A177	R:R:R181	2.77	No	Yes	0	6	7
237	R:R:A119	R:R:Y328	2.67	No	Yes	0	7	7
238	R:R:H299	R:R:I298	2.65	Yes	No	0	7	6
239	R:R:F345	R:R:V94	2.62	Yes	No	0	8	7
240	R:R:F349	R:R:V94	2.62	No	No	0	6	7
241	R:R:E312	R:R:Q316	2.55	No	Yes	0	2	3
242	R:R:I188	R:R:R184	2.51	No	No	0	3	3
243	R:R:F158	R:R:L196	2.44	No	No	0	5	4
244	R:R:A104	R:R:P183	1.87	No	No	0	5	1
245	R:R:G269	R:R:S268	1.86	No	No	0	1	4
246	R:R:A104	R:R:A186	1.79	No	No	0	5	7
247	R:R:P183	R:R:T182	1.75	No	No	0	1	7
248	R:R:G269	R:R:K273	1.74	No	No	0	1	3
249	R:R:A325	R:R:V80	1.7	No	No	0	6	7
250	R:R:C294	R:R:T329	1.69	No	No	0	9	5
251	R:R:I310	R:R:P311	1.69	No	No	0	4	1
252	R:R:M207	R:R:P203	1.68	No	No	0	5	8
253	R:R:L202	R:R:P203	1.64	No	No	0	4	8
254	R:R:V286	R:R:V290	1.6	No	No	0	6	7
255	R:R:T69	R:R:V318	1.59	No	No	0	4	1
256	R:R:T251	R:R:V247	1.59	No	No	0	5	6
257	R:R:T251	R:R:V288	1.59	No	No	0	5	8
258	R:R:I310	R:R:V308	1.54	No	No	0	4	2
259	R:R:M67	R:R:S66	1.53	No	No	0	2	7
260	R:R:H173	R:R:P174	1.53	No	No	0	6	8
261	R:R:I68	R:R:T72	1.52	No	No	0	3	4
262	R:R:K102	R:R:T103	1.5	No	No	0	7	7
263	R:R:K143	R:R:T139	1.5	No	No	0	6	3
264	R:R:K143	R:R:T209	1.5	No	No	0	6	5
265	R:R:L307	R:R:V308	1.49	No	No	0	5	2
266	R:R:L285	R:R:T281	1.47	No	No	0	5	6
267	R:R:I258	R:R:K262	1.45	No	No	0	5	4
268	R:R:K100	R:R:K102	1.44	No	No	0	6	7
269	R:R:K143	R:R:M205	1.44	No	No	0	6	5
270	R:R:E272	R:R:S270	1.44	No	No	0	3	2
271	R:R:I188	R:R:N185	1.42	No	No	0	3	4
272	R:R:G138	R:R:W135	1.41	No	Yes	0	7	8
273	R:R:E231	R:R:T227	1.41	No	No	0	4	3
274	R:R:K346	R:R:L341	1.41	No	No	0	8	7
275	R:R:L256	R:R:L259	1.38	No	No	0	5	2
276	R:R:R213	R:R:S216	1.32	No	No	0	2	1
277	R:R:V94	R:R:Y98	1.26	No	No	0	7	4
278	R:R:R278	R:R:R282	1.07	No	No	0	5	5
279	R:R:R279	R:R:R282	1.07	No	No	0	7	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y108	6.9475	4	0	7
2	R:R:L112	5.642	5	1	9
3	R:R:D116	7.876	5	1	9
4	R:R:Q126	8.5325	4	2	6
5	R:R:W135	9.39	8	3	8
6	R:R:F137	10.73	5	3	6
7	R:R:D149	11.8	4	2	5
8	R:R:Y151	6.378	5	4	5
9	R:R:F154	5.62	4	0	6
10	R:R:T155	8.255	4	4	7
11	R:R:Y168	8.03	4	0	8
12	R:R:R181	7.5875	4	0	7
13	R:R:W194	9.6725	4	4	9
14	R:R:F223	5.235	4	0	6
15	R:R:W230	4.47	5	6	1
16	R:R:K235	4.055	4	0	4
17	R:R:Y254	7.168	5	0	9
18	R:R:F291	5.998	5	1	9
19	R:R:W295	8.03667	6	1	8
20	R:R:H299	8.1525	4	0	7
21	R:R:Q316	4.8125	4	0	3
22	R:R:W320	7.4075	4	0	4
23	R:R:H321	9.39	4	5	4
24	R:R:Y328	8.61	5	2	7
25	R:R:N330	7.5375	4	1	9
26	R:R:N334	7.9	5	1	9
27	R:R:P335	3.8425	4	0	9
28	R:R:Y338	6.888	5	1	9
29	R:R:F345	4.698	5	0	8
30	L:L:?1	11.3822	9	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:H321	R:R:I73	12.171	3.98	Yes	No	5	4	6
2	R:R:H321	R:R:Y77	10.5801	13.07	Yes	No	0	4	7
3	R:R:C332	R:R:G84	11.5032	3.92	No	No	0	8	8
4	R:R:G84	R:R:T120	13.3757	3.64	No	No	0	8	5
5	R:R:L85	R:R:T120	15.235	5.9	No	No	0	6	5
6	R:R:F89	R:R:L85	17.0813	3.65	No	No	0	4	6
7	R:R:A117	R:R:F89	80.0249	4.16	No	No	0	7	4
8	R:R:A117	R:R:N88	81.3343	4.69	No	No	0	7	9
9	R:R:D116	R:R:N88	87.5082	6.73	Yes	No	0	9	9
10	R:R:D116	R:R:N334	72.5743	8.08	Yes	Yes	1	9	9
11	R:R:N330	R:R:N334	77.6548	9.54	Yes	Yes	1	9	9
12	R:R:N330	R:R:W295	73.3534	7.91	Yes	Yes	1	9	8
13	R:R:M153	R:R:W295	100	5.82	No	Yes	0	7	8
14	L:L:?1	R:R:M153	99.5744	8.11	Yes	No	0	0	7
15	L:L:?1	R:R:I324	44.16	7.02	Yes	No	0	0	5
16	R:R:I324	R:R:Y77	16.1123	7.25	No	No	0	5	7
17	R:R:I324	R:R:W320	27.4191	7.05	No	Yes	0	5	4
18	R:R:H321	R:R:W320	10.9402	6.35	Yes	Yes	0	4	4
19	R:R:N88	R:R:P335	20.2174	4.89	No	Yes	0	9	9
20	R:R:F89	R:R:M92	66.2106	4.98	No	No	0	4	7
21	R:R:L114	R:R:M92	60.3182	4.24	No	No	0	7	7
22	R:R:F345	R:R:I109	16.5575	5.02	Yes	No	0	8	8
23	R:R:I109	R:R:M163	18.2925	4.37	No	No	0	8	9
24	R:R:M163	R:R:Y338	20.0864	7.18	No	Yes	0	9	9
25	R:R:N334	R:R:Y338	37.0892	8.14	Yes	Yes	1	9	9
26	R:R:D166	R:R:Y108	22.3648	6.9	No	Yes	0	8	7
27	R:R:N190	R:R:Y108	38.045	10.47	No	Yes	0	7	7
28	R:R:N111	R:R:N190	39.7211	13.62	No	No	0	9	7
29	R:R:N111	R:R:W194	41.384	6.78	No	Yes	0	9	9
30	R:R:L114	R:R:W194	58.8124	4.56	No	Yes	0	7	9
31	R:R:A186	R:R:Y108	11.5032	6.67	No	Yes	0	7	7
32	R:R:W194	R:R:Y151	13.2382	11.58	Yes	Yes	4	9	5
33	R:R:C219	R:R:W135	27.8971	20.89	No	Yes	3	9	8
34	R:R:C219	R:R:I146	40.9192	4.91	No	No	0	9	4
35	L:L:?1	R:R:I146	43.322	7.02	Yes	No	0	0	4
36	R:R:I217	R:R:W135	12.8781	3.52	No	Yes	0	4	8
37	R:R:C142	R:R:C219	11.8829	7.28	No	No	3	9	9
38	R:R:C142	R:R:T210	11.3133	3.38	No	No	0	9	4
39	R:R:F291	R:R:W295	28.1262	7.02	Yes	Yes	1	9	8
40	R:R:S164	R:R:Y254	20.8001	10.17	No	Yes	0	9	9
41	R:R:V288	R:R:Y254	31.3212	3.79	No	Yes	0	8	9
42	R:R:I250	R:R:V288	27.3537	4.61	No	No	0	8	8
43	R:R:F291	R:R:I250	28.3357	8.79	Yes	No	0	9	8
44	R:R:D166	R:R:F180	13.3691	4.78	No	No	0	8	3
45	R:R:C253	R:R:Y168	16.7147	6.72	No	Yes	0	8	8
46	R:R:C253	R:R:S164	18.7639	3.44	No	No	0	8	9
47	R:R:L267	R:R:L277	26.5026	11.07	No	No	0	1	6
48	R:R:L277	R:R:T281	28.4863	2.95	No	No	0	6	6
49	R:R:I258	R:R:T281	32.4211	9.12	No	No	0	5	6
50	R:R:I258	R:R:V284	36.3101	6.14	No	No	0	5	8
51	R:R:V284	R:R:Y254	38.2087	8.83	No	Yes	0	8	9
52	R:R:E231	R:R:F223	21.9916	9.33	No	Yes	0	4	6
53	R:R:E231	R:R:K235	24.9247	4.05	No	Yes	0	4	4
54	R:R:K235	R:R:V302	29.0363	4.55	Yes	No	0	4	5
55	L:L:?1	R:R:V302	30.2737	10.99	Yes	No	0	0	5
56	R:R:F223	R:R:W230	12.8715	3.01	Yes	Yes	0	6	1
57	R:R:I244	R:R:M245	10.9533	2.92	No	No	0	4	5
58	R:R:F239	R:R:I244	12.7341	11.3	No	No	0	6	4
59	R:R:F239	R:R:H299	14.5018	4.53	No	Yes	0	6	7
60	R:R:H299	R:R:W295	26.6335	8.46	Yes	Yes	0	7	8
61	R:R:F243	R:R:H299	11.3133	16.97	No	Yes	0	8	7
62	R:R:V287	R:R:Y338	42.8375	5.05	No	Yes	0	8	9
63	R:R:I280	R:R:N276	16.5445	4.25	No	No	0	8	5
64	R:R:I280	R:R:L267	18.5871	2.85	No	No	0	8	1
65	R:R:N276	R:R:R279	14.4821	8.44	No	No	0	5	7
66	R:R:L337	R:R:V287	10.3378	4.47	No	No	0	8	8
67	R:R:Q316	R:R:Y301	12.5376	5.64	Yes	No	0	3	5
68	R:R:W320	R:R:Y301	15.4315	5.79	Yes	No	0	4	5
69	R:R:F340	R:R:P335	10.1611	2.89	No	Yes	0	6	9
70	R:R:D116	R:R:L112	18.3645	5.43	Yes	Yes	1	9	9
71	R:R:L112	R:R:Y338	17.8735	5.86	Yes	Yes	1	9	9
72	R:R:V287	R:R:Y254	33.9793	3.79	No	Yes	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:I324	R:R:Y77	7.25	0	No	No	5	7	1	2
R:R:Q126	R:R:T122	5.67	2	Yes	No	6	6	1	2
R:R:D149	R:R:T122	7.23	2	Yes	No	5	6	1	2
R:R:L123	R:R:Y328	16.41	0	No	Yes	7	7	2	1
R:R:D149	R:R:Q126	5.22	2	Yes	Yes	5	6	1	1
R:R:Q126	R:R:Y328	10.15	2	Yes	Yes	6	7	1	1
L:L:?1	R:R:Q126	13.09	2	Yes	Yes	0	6	0	1
R:R:A208	R:R:I146	6.5	0	No	No	5	4	2	1
R:R:C219	R:R:I146	4.91	3	No	No	9	4	2	1
L:L:?1	R:R:I146	7.02	2	Yes	No	0	4	0	1
R:R:D149	R:R:Y328	8.05	2	Yes	Yes	5	7	1	1
L:L:?1	R:R:D149	26.7	2	Yes	Yes	0	5	0	1
R:R:V204	R:R:Y150	8.83	2	No	No	5	4	2	1
R:R:L221	R:R:Y150	7.03	2	No	No	4	4	2	1
L:L:?1	R:R:Y150	11.53	2	Yes	No	0	4	0	1
R:R:M153	R:R:W295	5.82	0	No	Yes	7	8	1	2
L:L:?1	R:R:M153	8.11	2	Yes	No	0	7	0	1
R:R:F154	R:R:V238	5.24	0	Yes	No	6	5	2	1
R:R:L221	R:R:V204	4.47	2	No	No	4	5	2	2
R:R:K235	R:R:V302	4.55	0	Yes	No	4	5	2	1
L:L:?1	R:R:V238	12.21	2	Yes	No	0	5	0	1
L:L:?1	R:R:V302	10.99	2	Yes	No	0	5	0	1
R:R:I324	R:R:W320	7.05	0	No	Yes	5	4	1	2
L:L:?1	R:R:I324	7.02	2	Yes	No	0	5	0	1
L:L:?1	R:R:Y328	5.77	2	Yes	Yes	0	7	0	1
R:R:A119	R:R:Y328	2.67	0	No	Yes	7	7	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8EFO_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.79
Number of Linked Nodes	260
Number of Links	279
Number of Hubs	30
Number of Links mediated by Hubs	120
Number of Communities	7
Number of Nodes involved in Communities	36
Number of Links involved in Communities	48

Path Summary
Number Of Nodes in MetaPath	73
Number Of Links MetaPath	72
Number of Shortest Paths	34585
Length Of Smallest Path	3
Average Path Length	13.5865
Length of Longest Path	31
Minimum Path Strength	1.07
Average Path Strength	6.59409
Maximum Path Strength	20.97
Minimum Path Correlation	0.7
Average Path Correlation	0.921812
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	53.7847
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	36.435
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	8QY
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	8QY
Name	PZM21
Synonyms	PZM21
Identifier
Formula	C19 H27 N3 O2 S
Molecular Weight	361.502
SMILES
PubChem	121596705
Formal Charge	0
Total Atoms	52
Total Chiral Atoms	2
Total Bonds	53
Total Aromatic Bonds	11


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P35372
Sequence	>8EFO_nogp_Chain_R S M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T K M K T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G T W P F G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H P V K A L D F R T P R N A K I I N V C N W I L S S A I G L P V M F M A T T K Y R Q G S I D C T L T F S H P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V R M L S G S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T I P E T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F K R C F R E F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	4DKL	A	Peptide	Opioid	μ	Mus musculus	β-Funaltrexamine	-	-	2.8	2012-03-21	doi.org/10.1038/nature10954
	5C1M	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.07	2015-08-05	doi.org/10.1038/nature14886
	6DDE	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-	Gi1/β1/γ2	3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDE (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-		3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDF	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-	Gi1/β1/γ2	3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-		3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	7SBF	A	Peptide	Opioid	μ	Mus musculus	PZM21	-	Gi1/β1/γ2	2.9	2022-04-20	doi.org/10.1002/anie.202200269
	7SBF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	PZM21	-		2.9	2022-04-20	doi.org/10.1002/anie.202200269
	7SCG	A	Peptide	Opioid	μ	Mus musculus	FH210	-	Gi1/β1/γ2	3	2022-04-20	doi.org/10.1002/anie.202200269
	7SCG (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	FH210	-		3	2022-04-20	doi.org/10.1002/anie.202200269
	7U2L	A	Peptide	Opioid	μ	Mus musculus	C5-guano	-	Gi1/β1/γ2	3.2	2022-05-04	doi.org/10.1038/s41586-022-05588-y
	7U2L (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	C5-guano	-		3.2	2022-05-04	doi.org/10.1038/s41586-022-05588-y
	7UL4	A	Peptide	Opioid	μ	Mus musculus	Alvimopan	-	-	2.8	2022-06-29	doi.org/10.1038/s41594-022-00859-8
	8EF5	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-	Gi1/β1/γ2	3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF5 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-		3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF6	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF6 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFB	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFB (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFL	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFL (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFO	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-	Gi1/β1/γ2	2.8	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFO (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-		2.8	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFQ	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Gi1/β1/γ2	3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFQ (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	7T2G	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-	Gi1/β1/γ2	2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2G (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-		2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2H	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-	Gi1/β1/γ2	2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2H (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-		2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7U2K	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-	Gi1/β1/γ2	3.3	2022-12-07	doi.org/10.1038/s41586-022-05588-y
	7U2K (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-		3.3	2022-12-07	doi.org/10.1038/s41586-022-05588-y
	8F7Q	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-	Gi1/β1/γ2	3.22	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7Q (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-		3.22	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7R	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Gi1/β1/γ2	3.28	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7R (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		3.28	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8K9K	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Gi3/β1/γ1	2.98	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9K (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.98	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9L	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	BMS-986122	Gi3/β1/γ1	3.05	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9L (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	BMS-986122		3.05	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	9BJK	A	Peptide	Opioid	μ	Mus musculus	Naloxone	PubChem 171642066	-	3.26	2024-07-17	doi.org/10.1038/s41586-024-07587-7
	9BQJ	A	Peptide	Opioid	μ	Mus musculus	RO76	-	Gi1/β1/γ2	3.3	2024-09-11	doi.org/10.1021/acscentsci.4c00525
	9BQJ (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	RO76	-		3.3	2024-09-11	doi.org/10.1021/acscentsci.4c00525
	9MQH	A	Peptide	Opioid	μ	Homo sapiens	-	-	-	3.9	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9MQI	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.3	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9MQJ	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.23	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9WST	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	chim(NtGi1-Gz)/β1/γ2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WST (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSV	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Arrestin2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSV (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSW	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	chim(NtGi1-Gz)/β1/γ2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSW (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSX	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Arrestin2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSX (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	8E0G	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.1	2023-10-18	doi.org/10.1186/s12915-023-01689-w
	8QOT	A	Peptide	Opioid	μ	Mus musculus	Nanobody-E	-	-	3.2	2023-12-27	doi.org/10.1101/2023.12.06.570395
	8Y72	A	Peptide	Opioid	μ	Homo sapiens	Peptide	BMS-986122	Gi1/β1/γ2	2.65	2025-08-06	To be published
	8Y72 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Peptide	BMS-986122		2.65	2025-08-06	To be published
	8Y73	A	Peptide	Opioid	μ	Homo sapiens	Peptide	MPAM-15	Gi1/β1/γ2	2.84	2025-08-06	To be published
	8Y73 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Peptide	MPAM-15		2.84	2025-08-06	To be published
	9PXU	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	Na	-	3.4	2025-11-12	10.1038/s41586-025-09677-6
	9PXV	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	-	Gi1/β1/γ2	3.02	2025-11-12	10.1038/s41586-025-09677-6
	9PXV (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	-		3.02	2025-11-12	10.1038/s41586-025-09677-6
	9PXW	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3.8	2025-11-12	10.1038/s41586-025-09677-6
	9PXW (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3.8	2025-11-12	10.1038/s41586-025-09677-6
	9PXX	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3.1	2025-11-12	10.1038/s41586-025-09677-6
	9PXX (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3.1	2025-11-12	10.1038/s41586-025-09677-6
	9PXY	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3	2025-11-12	10.1038/s41586-025-09677-6
	9PXY (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3	2025-11-12	10.1038/s41586-025-09677-6
	9PY2	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	3.16	2025-11-12	10.1038/s41586-025-09677-6
	9PY2 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		3.16	2025-11-12	10.1038/s41586-025-09677-6
	9PY3	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	3.2	2025-11-12	To be published
	9PY3 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		3.2	2025-11-12	To be published
	9PY4	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	2.78	2025-11-12	10.1038/s41586-025-09677-6
	9PY4 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		2.78	2025-11-12	10.1038/s41586-025-09677-6
	9ODJ	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg	Gi1/β1/γ2	3	2026-01-07	10.1038/s41586-025-10056-4
	9ODJ (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg		3	2026-01-07	10.1038/s41586-025-10056-4
	9ODK	A	Peptide	Opioid	μ	Mus musculus	-	GTP; Mg	Gi1/β1/γ2	3.9	2026-01-07	10.1038/s41586-025-10056-4
	9ODK (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	-	GTP; Mg		3.9	2026-01-07	10.1038/s41586-025-10056-4
	9ODL	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg	Gi1/β1/γ2	3.6	2026-01-07	10.1038/s41586-025-10056-4
	9ODL (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg		3.6	2026-01-07	10.1038/s41586-025-10056-4

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8EFO_nogp.zip

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