Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:Y1 8.238500
2L:L:P2 7.9125410
3L:L:W3 9.02667610
4L:L:F4 6.766510
5R:R:I73 8.0425416
6R:R:Y77 8.6525417
7R:R:V80 2.7775407
8R:R:V91 3.1175409
9R:R:Y108 6.9275407
10R:R:L112 6.15167629
11R:R:D116 7.802529
12R:R:Q126 5.952516
13R:R:W135 8.18125818
14R:R:F137 10.04516
15R:R:Y151 7.34435
16R:R:N152 6.335408
17R:R:T155 5.444537
18R:R:F158 4.72435
19R:R:M163 6.41429
20R:R:Y168 8.3025408
21R:R:W194 10.6775439
22R:R:W230 6.17551
23R:R:F239 7426
24R:R:F243 8.2525428
25R:R:P246 4.0225408
26R:R:Y254 7.418509
27R:R:L267 4.3025401
28R:R:R279 6.74407
29R:R:F291 5.86429
30R:R:W295 7.272528
31R:R:T296 4.61405
32R:R:I298 3.5375416
33R:R:H299 5.8427
34R:R:I310 3.528514
35R:R:Q316 4.116513
36R:R:W320 5.11167614
37R:R:H321 12.028514
38R:R:I324 5.702515
39R:R:N330 7.5675429
40R:R:N334 7.84429
41R:R:Y338 6.074529
42R:R:F345 5.4625408
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1L:L:P2 L:L:Y1 10019.47YesYes000
2L:L:Y1 R:R:M153 41.70917.18YesNo007
3L:L:Y1 R:R:V238 27.65546.31YesNo005
4L:L:Y1 R:R:H299 72.41743.27YesYes007
5L:L:?5 L:L:F4 36.71813.01NoYes000
6L:L:F4 R:R:I324 77.02928.79YesYes105
7L:L:P2 R:R:I324 76.1983.39YesYes105
8L:L:?5 L:L:W3 35.557511.28NoYes000
9L:L:F4 R:R:Q126 55.93145.86YesYes106
10L:L:W3 R:R:Q126 50.92127.67YesYes106
11L:L:W3 R:R:C219 14.873410.45YesNo109
12L:L:P2 R:R:W320 19.93345.4YesYes104
13R:R:H321 R:R:W320 18.61193.17YesYes144
14L:L:W3 R:R:W135 59.0577.5YesYes108
15R:R:P136 R:R:W135 27.69375.4NoYes138
16R:R:M132 R:R:P136 25.36875.03NoNo043
17R:R:H321 R:R:I73 10.384218.56YesYes146
18R:R:F243 R:R:H299 37.41539.05YesYes287
19R:R:F243 R:R:T296 22.051610.38YesYes085
20R:R:P297 R:R:T296 17.42443.5NoYes095
21R:R:L326 R:R:P297 16.22944.93NoNo089
22R:R:L326 R:R:T329 11.27284.42NoNo085
23R:R:T329 R:R:V80 10.05483.17NoYes057
24R:R:L123 R:R:Y328 10.012621.1NoNo077
25R:R:M153 R:R:W295 41.75133.49NoYes078
26R:R:N330 R:R:W295 42.341114.69YesYes298
27R:R:N330 R:R:N334 43.98824.09YesYes299
28R:R:H299 R:R:W295 52.79816.35YesYes278
29R:R:Q126 R:R:T122 30.34054.25YesNo166
30R:R:I148 R:R:T122 33.34353.04NoNo056
31R:R:I148 R:R:N152 33.45465.66NoYes058
32R:R:N152 R:R:T155 34.38924.39YesYes087
33R:R:T155 R:R:W194 26.326310.92YesYes379
34R:R:L114 R:R:W194 31.71184.56NoYes079
35R:R:L114 R:R:M92 30.47842.83NoNo077
36R:R:F110 R:R:M92 29.23746.22NoNo067
37R:R:F110 R:R:I95 26.73237.54NoNo067
38R:R:I95 R:R:V91 25.46833.07NoYes079
39R:R:A339 R:R:V91 20.33553.39NoYes069
40R:R:A339 R:R:F345 19.03325.55NoYes068
41R:R:L112 R:R:N334 28.58629.61YesYes299
42R:R:L112 R:R:M163 11.4957.07YesYes299
43R:R:M163 R:R:Y108 21.13233.59YesYes097
44R:R:A186 R:R:Y108 13.37195.34NoYes077
45R:R:A186 R:R:I107 10.45316.5NoNo075
46R:R:L112 R:R:T159 26.85494.42YesNo298
47R:R:N111 R:R:T159 43.13413.16NoNo098
48R:R:L112 R:R:Y338 18.01053.52YesYes299
49R:R:M132 R:R:T134 15.27186.02NoNo045
50R:R:C142 R:R:W135 12.92376.53NoYes198
51R:R:C142 R:R:C219 12.54075.46NoNo199
52R:R:C142 R:R:T210 20.38923.38NoNo094
53R:R:N139 R:R:T210 15.302414.62NoNo034
54R:R:F291 R:R:W295 50.84469.02YesYes298
55R:R:F291 R:R:P246 13.6635.78YesYes098
56R:R:F291 R:R:I250 43.39075.02YesNo098
57R:R:I250 R:R:S164 42.20326.19NoNo089
58R:R:C253 R:R:S164 21.17823.44NoNo089
59R:R:S164 R:R:Y254 36.806211.45NoYes099
60R:R:F243 R:R:V247 26.59443.93YesNo086
61R:R:T251 R:R:V247 26.34161.59NoNo056
62R:R:T251 R:R:V288 20.6421.59NoNo058
63R:R:V288 R:R:Y254 20.68415.05NoYes089
64R:R:R167 R:R:Y254 25.09678.23NoYes099
65R:R:R167 R:R:Y338 25.79775.14NoYes099
66R:R:C253 R:R:Y168 15.84638.06NoYes088
67R:R:H173 R:R:Y168 11.48738.71NoYes068
68R:R:L234 R:R:V238 23.99362.98NoNo065
69R:R:L234 R:R:W230 22.31973.42NoYes061
70R:R:M207 R:R:W230 11.2928.14NoYes051
71R:R:S216 R:R:T134 12.69771.6NoNo015
72R:R:V284 R:R:Y254 51.97847.57NoYes089
73R:R:I258 R:R:V284 50.0444.61NoNo058
74R:R:I258 R:R:T281 45.77324.56NoNo056
75R:R:L277 R:R:T281 41.48312.95NoNo066
76R:R:L267 R:R:L277 39.59865.54YesNo016
77R:R:L267 R:R:V264 20.377.45YesNo016
78R:R:M266 R:R:V264 18.13691.52NoNo046
79R:R:K273 R:R:M266 15.89617.2NoNo034
80R:R:K273 R:R:S270 11.39164.59NoNo032
81R:R:L267 R:R:N276 15.37141.37YesNo015
82R:R:N276 R:R:R279 13.12296.03NoYes057
83R:R:V287 R:R:Y338 15.81195.05NoYes089
84R:R:K305 R:R:W320 13.87755.8NoYes134
85R:R:I73 R:R:T69 16.65451.52YesNo064
86R:R:N111 R:R:W194 42.29914.69NoYes099
87L:L:F4 R:R:H321 12.12327.92YesYes104
88R:R:M163 R:R:T159 16.9383.01YesNo298
89R:R:M163 R:R:Y338 16.363411.97YesYes299
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:Y1 R:R:Y150 4.96 0 Yes No 0 4 0 1
L:L:Y1 R:R:M153 7.18 0 Yes No 0 7 0 1
L:L:Y1 R:R:V238 6.31 0 Yes No 0 5 0 1
L:L:Y1 R:R:H299 3.27 0 Yes Yes 0 7 0 1
L:L:P2 R:R:I298 3.39 1 Yes Yes 0 6 0 1
L:L:P2 R:R:W320 5.4 1 Yes Yes 0 4 0 1
L:L:P2 R:R:I324 3.39 1 Yes Yes 0 5 0 1
L:L:W3 R:R:Q126 7.67 1 Yes Yes 0 6 0 1
L:L:W3 R:R:N129 9.04 1 Yes No 0 4 0 1
L:L:W3 R:R:W135 7.5 1 Yes Yes 0 8 0 1
L:L:W3 R:R:I146 8.22 1 Yes No 0 4 0 1
L:L:W3 R:R:C219 10.45 1 Yes No 0 9 0 1
L:L:F4 R:R:Y77 8.25 1 Yes Yes 0 7 0 1
L:L:F4 R:R:Q126 5.86 1 Yes Yes 0 6 0 1
L:L:F4 R:R:H321 7.92 1 Yes Yes 0 4 0 1
L:L:F4 R:R:I324 8.79 1 Yes Yes 0 5 0 1
R:R:I73 R:R:Y77 7.25 1 Yes Yes 6 7 2 1
R:R:I73 R:R:Y130 4.84 1 Yes No 6 5 2 2
R:R:H321 R:R:I73 18.56 1 Yes Yes 4 6 1 2
R:R:H321 R:R:Y77 13.07 1 Yes Yes 4 7 1 1
R:R:I324 R:R:Y77 6.04 1 Yes Yes 5 7 1 1
R:R:Q126 R:R:T122 4.25 1 Yes No 6 6 1 2
R:R:D149 R:R:T122 10.12 1 No No 5 6 2 2
R:R:F125 R:R:W135 5.01 1 No Yes 6 8 2 1
R:R:F125 R:R:F137 10.72 1 No Yes 6 6 2 2
R:R:D149 R:R:Q126 5.22 1 No Yes 5 6 2 1
R:R:Q126 R:R:Y328 6.76 1 Yes No 6 7 1 2
R:R:N129 R:R:W135 10.17 1 No Yes 4 8 1 1
R:R:H321 R:R:Y130 17.42 1 Yes No 4 5 1 2
R:R:P136 R:R:W135 5.4 1 No Yes 3 8 2 1
R:R:F137 R:R:W135 18.04 1 Yes Yes 6 8 2 1
R:R:C142 R:R:W135 6.53 1 No Yes 9 8 2 1
R:R:C219 R:R:W135 10.45 1 No Yes 9 8 1 1
R:R:F137 R:R:P136 10.11 1 Yes No 6 3 2 2
R:R:C142 R:R:C219 5.46 1 No No 9 9 2 1
R:R:A208 R:R:I146 4.87 0 No No 5 4 2 1
R:R:D149 R:R:Y328 5.75 1 No No 5 7 2 2
R:R:M153 R:R:W295 3.49 0 No Yes 7 8 1 2
R:R:F239 R:R:F243 9.65 2 Yes Yes 6 8 2 2
R:R:F239 R:R:H299 4.53 2 Yes Yes 6 7 2 1
R:R:F243 R:R:H299 9.05 2 Yes Yes 8 7 2 1
R:R:H299 R:R:W295 6.35 2 Yes Yes 7 8 1 2
R:R:I298 R:R:V302 3.07 1 Yes No 6 5 1 2
R:R:C323 R:R:I298 3.27 0 No Yes 6 6 2 1
R:R:I298 R:R:I324 4.42 1 Yes Yes 6 5 1 1
R:R:W320 R:R:Y301 6.75 1 Yes No 4 5 1 2
R:R:V302 R:R:W320 3.68 0 No Yes 5 4 2 1
R:R:K305 R:R:W320 5.8 1 No Yes 3 4 2 1
R:R:H321 R:R:W320 3.17 1 Yes Yes 4 4 1 1
R:R:I324 R:R:W320 5.87 1 Yes Yes 5 4 1 1
R:R:L234 R:R:V238 2.98 0 No No 6 5 2 1
R:R:I217 R:R:W135 2.35 0 No Yes 4 8 2 1
R:R:G133 R:R:N129 1.7 0 No No 2 4 2 1
R:R:A242 R:R:V238 1.7 0 No No 5 5 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 9WSW_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3
Number of Linked Nodes 266
Number of Links 302
Number of Hubs 42
Number of Links mediated by Hubs 151
Number of Communities 6
Number of Nodes involved in Communities 57
Number of Links involved in Communities 80
Path Summary
Number Of Nodes in MetaPath 90
Number Of Links MetaPath 89
Number of Shortest Paths 64806
Length Of Smallest Path 3
Average Path Length 14.1986
Length of Longest Path 33
Minimum Path Strength 1.22
Average Path Strength 6.43287
Maximum Path Strength 17.49
Minimum Path Correlation 0.7
Average Path Correlation 0.923277
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 3.84615
Average % Of Corr. Nodes 46.1451
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 49.5417
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• G protein-coupled receptor-like   • Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• G protein-coupled receptor-like   • Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeNH2
PDB ResiduesL:L:?5
Environment DetailsOpen EMBL-EBI Page
CodeNH2
NameAMINO GROUP
Synonyms
Identifier
FormulaH2 N
Molecular Weight16.023
SMILES
PubChem123329
Formal Charge0
Total Atoms3
Total Chiral Atoms0
Total Bonds2
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP35372
Sequence
>9WSW_nogp_Chain_R
MTAITIMAL YSIVCVVGL FGNFLVMYV IVRYTKMKT ATNIYIFNL 
ALADALATS TLPFQSVNY LMGTWPFGI LCKIVISID YYNMFTSIF 
TLCTMSVDR YIAVCHPVK ALDFRTPRN AKINVCNWI LSSAIGLPV 
MFMATTKYR QGSIDCTLT FSHPTWYWE NLLKICVFI FAFIMPVLI 
ITVCYGLMI LRLKSVRML SGSKEKDRN LRRITRMVL VVVAVFIVC 
WTPIHIYVI IKALTIPET TFQTVSWHF CIALGYTNS CLNPVLYAF 
LDENFKRCF VNVI


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
4DKLAPeptideOpioidμMus musculusβ-Funaltrexamine--2.82012-03-21doi.org/10.1038/nature10954
5C1MAPeptideOpioidμMus musculusBU72--2.072015-08-05doi.org/10.1038/nature14886
6DDEAPeptideOpioidμMus musculusDAMGO-Gi1/β1/γ23.52018-06-13doi.org/10.1038/s41586-018-0219-7
6DDE (No Gprot) APeptideOpioidμMus musculusDAMGO-3.52018-06-13doi.org/10.1038/s41586-018-0219-7
6DDFAPeptideOpioidμMus musculusDAMGO-Gi1/β1/γ23.52018-06-13doi.org/10.1038/s41586-018-0219-7
6DDF (No Gprot) APeptideOpioidμMus musculusDAMGO-3.52018-06-13doi.org/10.1038/s41586-018-0219-7
7SBFAPeptideOpioidμMus musculusPZM21-Gi1/β1/γ22.92022-04-20doi.org/10.1002/anie.202200269
7SBF (No Gprot) APeptideOpioidμMus musculusPZM21-2.92022-04-20doi.org/10.1002/anie.202200269
7SCGAPeptideOpioidμMus musculusFH210-Gi1/β1/γ232022-04-20doi.org/10.1002/anie.202200269
7SCG (No Gprot) APeptideOpioidμMus musculusFH210-32022-04-20doi.org/10.1002/anie.202200269
7U2LAPeptideOpioidμMus musculusC5-guano-Gi1/β1/γ23.22022-05-04doi.org/10.1038/s41586-022-05588-y
7U2L (No Gprot) APeptideOpioidμMus musculusC5-guano-3.22022-05-04doi.org/10.1038/s41586-022-05588-y
7UL4APeptideOpioidμMus musculusAlvimopan--2.82022-06-29doi.org/10.1038/s41594-022-00859-8
8EF5APeptideOpioidμHomo sapiensFentanyl-Gi1/β1/γ23.32022-11-09doi.org/10.1016/j.cell.2022.09.041
8EF5 (No Gprot) APeptideOpioidμHomo sapiensFentanyl-3.32022-11-09doi.org/10.1016/j.cell.2022.09.041
8EF6APeptideOpioidμHomo sapiensMorphine-Gi1/β1/γ23.22022-11-09doi.org/10.1016/j.cell.2022.09.041
8EF6 (No Gprot) APeptideOpioidμHomo sapiensMorphine-3.22022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFBAPeptideOpioidμHomo sapiensOliceridine-Gi1/β1/γ23.22022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFB (No Gprot) APeptideOpioidμHomo sapiensOliceridine-3.22022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFLAPeptideOpioidμHomo sapiensSR17018-Gi1/β1/γ23.22022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFL (No Gprot) APeptideOpioidμHomo sapiensSR17018-3.22022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFOAPeptideOpioidμHomo sapiensPZM21-Gi1/β1/γ22.82022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFO (No Gprot) APeptideOpioidμHomo sapiensPZM21-2.82022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFQAPeptideOpioidμHomo sapiensDAMGO-Gi1/β1/γ23.32022-11-09doi.org/10.1016/j.cell.2022.09.041
8EFQ (No Gprot) APeptideOpioidμHomo sapiensDAMGO-3.32022-11-09doi.org/10.1016/j.cell.2022.09.041
7T2GAPeptideOpioidμMus musculusMitragynine Pseudoindoxyl-Gi1/β1/γ22.52022-12-07doi.org/10.1038/s41589-022-01208-y
7T2G (No Gprot) APeptideOpioidμMus musculusMitragynine Pseudoindoxyl-2.52022-12-07doi.org/10.1038/s41589-022-01208-y
7T2HAPeptideOpioidμMus musculusLofentanil-Gi1/β1/γ22.52022-12-07doi.org/10.1038/s41589-022-01208-y
7T2H (No Gprot) APeptideOpioidμMus musculusLofentanil-2.52022-12-07doi.org/10.1038/s41589-022-01208-y
7U2KAPeptideOpioidμMus musculusC6-guano-Gi1/β1/γ23.32022-12-07doi.org/10.1038/s41586-022-05588-y
7U2K (No Gprot) APeptideOpioidμMus musculusC6-guano-3.32022-12-07doi.org/10.1038/s41586-022-05588-y
8F7QAPeptideOpioidμHomo sapiensβ-Endorphin-Gi1/β1/γ23.222022-12-14doi.org/10.1016/j.cell.2022.12.026
8F7Q (No Gprot) APeptideOpioidμHomo sapiensβ-Endorphin-3.222022-12-14doi.org/10.1016/j.cell.2022.12.026
8F7RAPeptideOpioidμHomo sapiensEndomorphin-Gi1/β1/γ23.282022-12-14doi.org/10.1016/j.cell.2022.12.026
8F7R (No Gprot) APeptideOpioidμHomo sapiensEndomorphin-3.282022-12-14doi.org/10.1016/j.cell.2022.12.026
8K9KAPeptideOpioidμHomo sapiensDAMGO-Gi3/β1/γ12.982024-05-29doi.org/10.1038/s41467-024-47792-6
8K9K (No Gprot) APeptideOpioidμHomo sapiensDAMGO-2.982024-05-29doi.org/10.1038/s41467-024-47792-6
8K9LAPeptideOpioidμHomo sapiensDAMGOBMS-986122Gi3/β1/γ13.052024-05-29doi.org/10.1038/s41467-024-47792-6
8K9L (No Gprot) APeptideOpioidμHomo sapiensDAMGOBMS-9861223.052024-05-29doi.org/10.1038/s41467-024-47792-6
9BJKAPeptideOpioidμMus musculusNaloxonePubChem 171642066-3.262024-07-17doi.org/10.1038/s41586-024-07587-7
9BQJAPeptideOpioidμMus musculusRO76-Gi1/β1/γ23.32024-09-11doi.org/10.1021/acscentsci.4c00525
9BQJ (No Gprot) APeptideOpioidμMus musculusRO76-3.32024-09-11doi.org/10.1021/acscentsci.4c00525
9MQHAPeptideOpioidμHomo sapiens---3.92025-02-12doi.org/10.1101/2025.01.09.632033
9MQIAPeptideOpioidμHomo sapiensIsoquinuclidine--3.32025-02-12doi.org/10.1101/2025.01.09.632033
9MQJAPeptideOpioidμHomo sapiensIsoquinuclidine--3.232025-02-12doi.org/10.1101/2025.01.09.632033
9WSTAPeptideOpioidμHomo sapiensDAMGO-chim(NtGi1-Gz)/β1/γ22.82025-11-2610.1038/s41422-025-01191-8
9WST (No Gprot) APeptideOpioidμHomo sapiensDAMGO-2.82025-11-2610.1038/s41422-025-01191-8
9WSVAPeptideOpioidμHomo sapiensDAMGO-Arrestin22.82025-11-2610.1038/s41422-025-01191-8
9WSV (No Gprot) APeptideOpioidμHomo sapiensDAMGO-2.82025-11-2610.1038/s41422-025-01191-8
9WSWAPeptideOpioidμHomo sapiensEndomorphin-chim(NtGi1-Gz)/β1/γ22.82025-11-2610.1038/s41422-025-01191-8
9WSW (No Gprot) APeptideOpioidμHomo sapiensEndomorphin-2.82025-11-2610.1038/s41422-025-01191-8
9WSXAPeptideOpioidμHomo sapiensEndomorphin-Arrestin22.82025-11-2610.1038/s41422-025-01191-8
9WSX (No Gprot) APeptideOpioidμHomo sapiensEndomorphin-2.82025-11-2610.1038/s41422-025-01191-8
8E0GAPeptideOpioidμMus musculusBU72--2.12023-10-18doi.org/10.1186/s12915-023-01689-w
8QOTAPeptideOpioidμMus musculusNanobody-E--3.22023-12-27doi.org/10.1101/2023.12.06.570395
8Y72APeptideOpioidμHomo sapiensPeptideBMS-986122Gi1/β1/γ22.652025-08-06To be published
8Y72 (No Gprot) APeptideOpioidμHomo sapiensPeptideBMS-9861222.652025-08-06To be published
8Y73APeptideOpioidμHomo sapiensPeptideMPAM-15Gi1/β1/γ22.842025-08-06To be published
8Y73 (No Gprot) APeptideOpioidμHomo sapiensPeptideMPAM-152.842025-08-06To be published
9PXUAPeptideOpioidμHomo sapiensNaloxoneNa-3.42025-11-1210.1038/s41586-025-09677-6
9PXVAPeptideOpioidμHomo sapiensNaloxone-Gi1/β1/γ23.022025-11-1210.1038/s41586-025-09677-6
9PXV (No Gprot) APeptideOpioidμHomo sapiensNaloxone-3.022025-11-1210.1038/s41586-025-09677-6
9PXWAPeptideOpioidμHomo sapiensNaloxoneGDPβSGi1/β1/γ23.82025-11-1210.1038/s41586-025-09677-6
9PXW (No Gprot) APeptideOpioidμHomo sapiensNaloxoneGDPβS3.82025-11-1210.1038/s41586-025-09677-6
9PXXAPeptideOpioidμHomo sapiensNaloxoneGDPβSGi1/β1/γ23.12025-11-1210.1038/s41586-025-09677-6
9PXX (No Gprot) APeptideOpioidμHomo sapiensNaloxoneGDPβS3.12025-11-1210.1038/s41586-025-09677-6
9PXYAPeptideOpioidμHomo sapiensNaloxoneGDPβSGi1/β1/γ232025-11-1210.1038/s41586-025-09677-6
9PXY (No Gprot) APeptideOpioidμHomo sapiensNaloxoneGDPβS32025-11-1210.1038/s41586-025-09677-6
9PY2APeptideOpioidμHomo sapiensLoperamideGDPβSGi1/β1/γ23.162025-11-1210.1038/s41586-025-09677-6
9PY2 (No Gprot) APeptideOpioidμHomo sapiensLoperamideGDPβS3.162025-11-1210.1038/s41586-025-09677-6
9PY3APeptideOpioidμHomo sapiensLoperamideGDPβSGi1/β1/γ23.22025-11-12To be published
9PY3 (No Gprot) APeptideOpioidμHomo sapiensLoperamideGDPβS3.22025-11-12To be published
9PY4APeptideOpioidμHomo sapiensLoperamideGDPβSGi1/β1/γ22.782025-11-1210.1038/s41586-025-09677-6
9PY4 (No Gprot) APeptideOpioidμHomo sapiensLoperamideGDPβS2.782025-11-1210.1038/s41586-025-09677-6
9ODJAPeptideOpioidμMus musculusMitragynine PseudoindoxylGTP; MgGi1/β1/γ232026-01-0710.1038/s41586-025-10056-4
9ODJ (No Gprot) APeptideOpioidμMus musculusMitragynine PseudoindoxylGTP; Mg32026-01-0710.1038/s41586-025-10056-4
9ODKAPeptideOpioidμMus musculus-GTP; MgGi1/β1/γ23.92026-01-0710.1038/s41586-025-10056-4
9ODK (No Gprot) APeptideOpioidμMus musculus-GTP; Mg3.92026-01-0710.1038/s41586-025-10056-4
9ODLAPeptideOpioidμMus musculusMitragynine PseudoindoxylGTP; MgGi1/β1/γ23.62026-01-0710.1038/s41586-025-10056-4
9ODL (No Gprot) APeptideOpioidμMus musculusMitragynine PseudoindoxylGTP; Mg3.62026-01-0710.1038/s41586-025-10056-4




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9WSW_nogp.zip



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You can also  read or  download a guide explaining the meaning of all files and numerical data.