psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I71	R:R:M67	5.83	No	No	0	5	2
2	R:R:T314	R:R:T69	4.71	No	No	0	1	4
3	R:R:I73	R:R:Y130	8.46	No	No	4	6	5
4	R:R:H321	R:R:I73	6.63	Yes	No	4	4	6
5	R:R:L131	R:R:M74	7.07	No	No	0	4	5
6	R:R:L123	R:R:Y77	4.69	Yes	Yes	0	7	7
7	R:R:S127	R:R:Y77	6.36	No	Yes	0	6	7
8	R:R:H321	R:R:Y77	13.07	Yes	Yes	0	4	7
9	R:R:I324	R:R:Y77	6.04	No	Yes	0	5	7
10	R:R:C81	R:R:L123	4.76	No	Yes	0	6	7
11	R:R:C81	R:R:P124	3.77	No	No	0	6	8
12	R:R:C332	R:R:G84	3.92	No	No	0	8	8
13	R:R:F89	R:R:L85	4.87	No	No	0	4	6
14	R:R:L85	R:R:T120	4.42	No	No	0	6	5
15	R:R:G87	R:R:P335	4.06	No	No	0	8	9
16	R:R:D116	R:R:N88	6.73	Yes	No	0	9	9
17	R:R:A117	R:R:N88	4.69	No	No	0	7	9
18	R:R:N88	R:R:P335	4.89	No	No	0	9	9
19	R:R:F340	R:R:L90	3.65	Yes	No	0	6	6
20	R:R:A113	R:R:V91	3.39	No	Yes	0	9	9
21	R:R:P335	R:R:V91	3.53	No	Yes	0	9	9
22	R:R:A339	R:R:V91	5.09	No	Yes	0	6	9
23	R:R:F340	R:R:V91	3.93	Yes	Yes	0	6	9
24	R:R:F110	R:R:M92	7.46	Yes	No	0	6	7
25	R:R:L114	R:R:M92	5.65	No	No	0	7	7
26	R:R:R97	R:R:Y93	11.32	No	No	0	5	4
27	R:R:F349	R:R:V94	3.93	No	No	0	6	7
28	R:R:F110	R:R:I95	7.54	Yes	No	0	6	7
29	R:R:F345	R:R:I95	5.02	Yes	No	0	8	7
30	R:R:R97	R:R:Y98	11.32	No	No	0	5	4
31	R:R:F352	R:R:Y98	13.41	No	No	0	7	4
32	R:R:N106	R:R:T99	5.85	No	No	5	8	6
33	R:R:F345	R:R:T99	3.89	Yes	No	5	8	6
34	R:R:F110	R:R:M101	6.22	Yes	No	0	6	7
35	R:R:N106	R:R:T103	5.85	No	No	0	8	7
36	R:R:R181	R:R:T105	5.17	No	No	0	7	8
37	R:R:F345	R:R:N106	7.25	Yes	No	5	8	8
38	R:R:T162	R:R:Y108	4.99	No	Yes	0	7	7
39	R:R:M163	R:R:Y108	3.59	No	Yes	0	9	7
40	R:R:D166	R:R:Y108	6.9	No	Yes	0	8	7
41	R:R:A186	R:R:Y108	6.67	No	Yes	0	7	7
42	R:R:N190	R:R:Y108	10.47	No	Yes	0	7	7
43	R:R:F345	R:R:I109	6.28	Yes	No	0	8	8
44	R:R:N111	R:R:N190	9.54	No	No	0	9	7
45	R:R:N111	R:R:W194	3.39	No	Yes	0	9	9
46	R:R:L112	R:R:T159	4.42	No	No	0	9	8
47	R:R:L112	R:R:Y338	4.69	No	Yes	0	9	9
48	R:R:L114	R:R:L118	4.15	No	No	0	7	7
49	R:R:L114	R:R:W194	3.42	No	Yes	0	7	9
50	R:R:D116	R:R:S156	5.89	Yes	No	0	9	9
51	R:R:D116	R:R:S331	7.36	Yes	No	0	9	9
52	R:R:D116	R:R:N334	8.08	Yes	Yes	0	9	9
53	R:R:L118	R:R:N152	10.98	No	Yes	0	7	8
54	R:R:T122	R:R:V145	4.76	No	No	0	6	5
55	R:R:D149	R:R:T122	4.34	Yes	No	0	5	6
56	R:R:L123	R:R:Y328	7.03	Yes	No	0	7	7
57	R:R:F125	R:R:W135	4.01	Yes	Yes	2	6	8
58	R:R:F125	R:R:F137	9.65	Yes	Yes	2	6	6
59	R:R:F125	R:R:L141	4.87	Yes	No	2	6	5
60	R:R:F125	R:R:V145	7.87	Yes	No	2	6	5
61	R:R:D149	R:R:Q126	3.92	Yes	No	6	5	6
62	R:R:Q126	R:R:Y328	5.64	No	No	6	6	7
63	R:R:F137	R:R:V128	6.55	Yes	No	0	6	3
64	R:R:N129	R:R:W135	7.91	No	Yes	0	4	8
65	R:R:T317	R:R:Y130	3.75	No	No	0	4	5
66	R:R:H321	R:R:Y130	11.98	Yes	No	4	4	5
67	R:R:M132	R:R:P136	8.39	No	No	0	4	3
68	R:R:F137	R:R:W135	20.04	Yes	Yes	2	6	8
69	R:R:C142	R:R:W135	6.53	Yes	Yes	2	9	8
70	R:R:V145	R:R:W135	4.9	No	Yes	2	5	8
71	R:R:C219	R:R:W135	20.89	No	Yes	2	9	8
72	R:R:F137	R:R:P136	5.78	Yes	No	0	6	3
73	R:R:F137	R:R:L141	6.09	Yes	No	2	6	5
74	R:R:T139	R:R:T210	10.99	No	No	0	3	4
75	R:R:C142	R:R:C219	7.28	Yes	No	2	9	9
76	R:R:M205	R:R:S147	9.2	No	No	0	5	6
77	R:R:I148	R:R:N152	4.25	No	Yes	0	5	8
78	R:R:D149	R:R:Y328	9.2	Yes	No	6	5	7
79	L:L:?1	R:R:D149	10.87	Yes	Yes	0	0	5
80	R:R:V204	R:R:Y150	6.31	No	No	0	5	4
81	R:R:L221	R:R:Y150	3.52	No	No	0	4	4
82	L:L:?1	R:R:Y150	15.02	Yes	No	0	0	4
83	R:R:N152	R:R:Y151	3.49	Yes	Yes	0	8	5
84	R:R:T155	R:R:Y151	7.49	Yes	Yes	3	7	5
85	R:R:W194	R:R:Y151	9.65	Yes	Yes	3	9	5
86	R:R:S197	R:R:Y151	3.82	No	Yes	3	8	5
87	R:R:F154	R:R:M153	3.73	Yes	No	0	6	7
88	R:R:M153	R:R:W295	5.82	No	Yes	0	7	8
89	L:L:?1	R:R:M153	10.19	Yes	No	0	0	7
90	R:R:F154	R:R:F158	5.36	Yes	No	0	6	5
91	R:R:F154	R:R:I200	12.56	Yes	No	0	6	5
92	R:R:F154	R:R:V238	7.87	Yes	No	0	6	5
93	R:R:A242	R:R:F154	4.16	No	Yes	0	5	6
94	R:R:T155	R:R:W194	14.55	Yes	Yes	3	7	9
95	R:R:S197	R:R:T155	6.4	No	Yes	3	8	7
96	R:R:I157	R:R:P246	3.39	No	No	0	7	8
97	R:R:F291	R:R:I157	3.77	Yes	No	1	9	7
98	R:R:I157	R:R:W295	9.4	No	Yes	1	7	8
99	R:R:L160	R:R:N334	4.12	No	Yes	1	8	9
100	R:R:L160	R:R:Y338	5.86	No	Yes	1	8	9
101	R:R:C161	R:R:P246	3.77	No	No	0	7	8
102	R:R:N193	R:R:T162	7.31	No	No	0	7	7
103	R:R:M163	R:R:Y338	4.79	No	Yes	0	9	9
104	R:R:I250	R:R:S164	4.64	No	No	1	8	9
105	R:R:C253	R:R:S164	3.44	No	No	0	8	9
106	R:R:S164	R:R:Y254	11.45	No	Yes	1	9	9
107	R:R:D166	R:R:F180	5.97	No	No	0	8	3
108	R:R:D166	R:R:R181	16.68	No	No	0	8	7
109	R:R:R167	R:R:Y254	8.23	No	Yes	0	9	9
110	R:R:M257	R:R:R167	4.96	No	No	0	8	9
111	R:R:C172	R:R:Y168	8.06	No	Yes	0	7	8
112	R:R:C253	R:R:Y168	6.72	No	Yes	0	8	8
113	R:R:L256	R:R:Y168	9.38	No	Yes	0	5	8
114	R:R:F180	R:R:I169	13.82	No	No	0	3	5
115	R:R:A170	R:R:R181	4.15	No	No	0	8	7
116	R:R:M257	R:R:V171	7.61	No	No	0	8	8
117	R:R:L261	R:R:V171	4.47	No	No	0	8	8
118	R:R:H173	R:R:K176	3.93	No	No	0	6	4
119	R:R:F180	R:R:N185	4.83	No	No	0	3	4
120	R:R:I188	R:R:R184	6.26	No	No	0	3	3
121	R:R:I189	R:R:N185	7.08	No	No	0	5	4
122	R:R:L202	R:R:S198	4.5	No	No	0	4	4
123	R:R:F223	R:R:M207	3.73	Yes	No	0	6	5
124	R:R:T209	R:R:T222	7.85	No	No	0	5	4
125	R:R:I217	R:R:Y212	4.84	No	No	0	4	3
126	R:R:D218	R:R:T220	7.23	No	No	0	4	4
127	R:R:F223	R:R:L221	3.65	Yes	No	0	6	4
128	R:R:E231	R:R:F223	5.83	No	Yes	0	4	6
129	R:R:F223	R:R:L234	4.87	Yes	No	0	6	6
130	R:R:S224	R:R:W230	4.94	No	Yes	0	3	1
131	R:R:H225	R:R:P226	6.1	No	No	0	2	4
132	R:R:P226	R:R:W228	10.81	No	No	0	4	1
133	R:R:W228	R:R:Y229	4.82	No	No	0	1	1
134	R:R:W230	R:R:Y229	4.82	Yes	No	0	1	1
135	R:R:E231	R:R:K235	9.45	No	No	0	4	4
136	L:L:?1	R:R:V238	4.77	Yes	No	0	0	5
137	R:R:F239	R:R:F243	5.36	Yes	Yes	1	6	8
138	R:R:F239	R:R:I244	6.28	Yes	No	1	6	4
139	R:R:F239	R:R:H299	5.66	Yes	No	1	6	7
140	R:R:F239	R:R:I303	8.79	Yes	No	0	6	5
141	R:R:F241	R:R:I240	3.77	No	No	0	4	5
142	R:R:F243	R:R:I244	3.77	Yes	No	1	8	4
143	R:R:F243	R:R:V247	3.93	Yes	No	0	8	6
144	R:R:F243	R:R:T296	7.78	Yes	No	0	8	5
145	R:R:F243	R:R:H299	10.18	Yes	No	1	8	7
146	R:R:I292	R:R:V247	4.61	No	No	0	6	6
147	R:R:I250	R:R:Y254	3.63	No	Yes	1	8	9
148	R:R:F291	R:R:I250	6.28	Yes	No	1	9	8
149	R:R:V284	R:R:Y254	8.83	No	Yes	0	8	9
150	R:R:V288	R:R:Y254	3.79	No	Yes	0	8	9
151	R:R:I258	R:R:T281	4.56	No	No	0	5	6
152	R:R:I258	R:R:V284	6.14	No	No	0	5	8
153	R:R:R260	R:R:V264	3.92	No	No	0	5	6
154	R:R:L261	R:R:L267	4.15	No	No	0	8	1
155	R:R:L267	R:R:V264	7.45	No	No	0	1	6
156	R:R:L267	R:R:L277	8.3	No	No	0	1	6
157	R:R:G269	R:R:S268	3.71	No	No	0	1	4
158	R:R:K273	R:R:S270	7.65	No	No	0	3	2
159	R:R:E272	R:R:R275	6.98	No	No	0	3	4
160	R:R:N276	R:R:R279	6.03	No	No	0	5	7
161	R:R:E343	R:R:R279	4.65	No	No	0	5	7
162	R:R:L341	R:R:M283	5.65	No	No	0	7	8
163	R:R:V287	R:R:Y338	3.79	No	Yes	0	8	9
164	R:R:L337	R:R:V290	4.47	No	No	0	8	7
165	R:R:F291	R:R:W295	7.02	Yes	Yes	1	9	8
166	R:R:F291	R:R:N330	4.83	Yes	Yes	1	9	9
167	R:R:C294	R:R:N330	7.87	No	Yes	0	9	9
168	R:R:H299	R:R:W295	8.46	No	Yes	1	7	8
169	R:R:G327	R:R:W295	4.22	No	Yes	0	7	8
170	R:R:N330	R:R:W295	10.17	Yes	Yes	1	9	8
171	R:R:P297	R:R:T296	3.5	No	No	0	9	5
172	L:L:?1	R:R:I298	6.86	Yes	No	0	0	6
173	R:R:Q316	R:R:Y301	6.76	Yes	No	0	3	5
174	R:R:S319	R:R:Y301	3.82	No	No	0	4	5
175	R:R:W320	R:R:Y301	5.79	Yes	No	0	4	5
176	L:L:?1	R:R:V302	5.96	Yes	No	0	0	5
177	R:R:K305	R:R:W320	9.28	No	Yes	0	3	4
178	R:R:I310	R:R:Q316	6.86	No	Yes	0	4	3
179	R:R:H321	R:R:W320	6.35	Yes	Yes	0	4	4
180	R:R:I324	R:R:W320	7.05	No	Yes	0	5	4
181	L:L:?1	R:R:W320	4.56	Yes	Yes	0	0	4
182	R:R:F322	R:R:L326	9.74	No	No	0	4	8
183	R:R:N330	R:R:N334	6.81	Yes	Yes	1	9	9
184	R:R:N334	R:R:Y338	5.81	Yes	Yes	1	9	9
185	R:R:F340	R:R:V336	3.93	Yes	No	0	6	6
186	R:R:F340	R:R:F349	4.29	Yes	No	0	6	6
187	R:R:D342	R:R:N344	6.73	No	No	0	8	7
188	R:R:D342	R:R:F345	10.75	No	Yes	0	8	8
189	R:R:E343	R:R:K346	6.75	No	No	0	5	8
190	R:R:C142	R:R:T210	3.38	Yes	No	0	9	4
191	R:R:A115	R:R:T155	3.36	No	Yes	0	8	7
192	R:R:C142	R:R:I146	3.27	Yes	No	2	9	4
193	R:R:C219	R:R:I146	3.27	No	No	2	9	4
194	R:R:H173	R:R:Y168	3.27	No	Yes	0	6	8
195	R:R:C323	R:R:I298	3.27	No	No	0	6	6
196	R:R:A208	R:R:I146	3.25	No	No	0	5	4
197	R:R:A306	R:R:K235	3.21	No	No	0	4	4
198	R:R:S216	R:R:T134	3.2	No	No	0	1	5
199	R:R:T329	R:R:V80	3.17	No	No	0	5	7
200	R:R:C81	R:R:L85	3.17	No	No	0	6	6
201	R:R:C237	R:R:L233	3.17	No	No	0	5	3
202	R:R:A325	R:R:L76	3.15	No	No	0	6	5
203	R:R:M74	R:R:S127	3.07	No	No	0	5	6
204	R:R:I169	R:R:V165	3.07	No	No	0	5	6
205	R:R:I195	R:R:V191	3.07	No	No	0	4	4
206	R:R:I217	R:R:T134	3.04	No	No	0	4	5
207	R:R:I217	R:R:T210	3.04	No	No	0	4	4
208	R:R:I300	R:R:T296	3.04	No	No	0	6	5
209	R:R:F223	R:R:W230	3.01	Yes	Yes	0	6	1
210	R:R:K102	R:R:T103	3	No	No	0	7	7
211	R:R:K211	R:R:T220	3	No	No	0	1	4
212	R:R:L123	R:R:V80	2.98	Yes	No	0	7	7
213	R:R:L256	R:R:V252	2.98	No	No	0	5	4
214	R:R:L337	R:R:V287	2.98	No	No	0	8	8
215	R:R:I144	R:R:I148	2.94	No	No	0	5	5
216	R:R:I236	R:R:I240	2.94	No	No	0	4	5
217	R:R:I300	R:R:I304	2.94	No	No	0	6	5
218	R:R:I107	R:R:K187	2.91	No	No	0	5	2
219	R:R:I258	R:R:K262	2.91	No	No	0	5	4
220	R:R:G201	R:R:Y151	2.9	No	Yes	0	6	5
221	R:R:I303	R:R:L307	2.85	No	No	0	5	5
222	R:R:I107	R:R:N190	2.83	No	No	0	5	7
223	R:R:I280	R:R:N276	2.83	No	No	0	8	5
224	R:R:L337	R:R:M283	2.83	No	No	0	8	8
225	R:R:C237	R:R:F241	2.79	No	No	0	5	4
226	R:R:R260	R:R:S263	2.64	No	No	0	5	3
227	R:R:F110	R:R:V96	2.62	Yes	No	0	6	3
228	R:R:F223	R:R:T227	2.59	Yes	No	0	6	3
229	R:R:E312	R:R:Q316	2.55	No	Yes	0	2	3
230	R:R:F241	R:R:M245	2.49	No	No	0	4	5
231	R:R:K271	R:R:R275	2.48	No	No	0	3	4
232	R:R:K346	R:R:R350	2.48	No	No	0	8	5
233	R:R:F86	R:R:L90	2.44	No	No	0	5	6
234	R:R:E351	R:R:F352	2.33	No	No	0	3	7
235	R:R:L233	R:R:W230	2.28	No	Yes	0	3	1
236	R:R:R347	R:R:R350	2.13	No	No	0	5	5
237	R:R:G201	R:R:S147	1.86	No	No	0	6	6
238	R:R:G84	R:R:T120	1.82	No	No	0	8	5
239	R:R:A104	R:R:A186	1.79	No	No	0	5	7
240	R:R:G133	R:R:M132	1.75	No	No	0	2	4
241	R:R:P183	R:R:T182	1.75	No	No	0	1	7
242	R:R:I107	R:R:P183	1.69	No	No	0	5	1
243	R:R:I310	R:R:P311	1.69	No	No	0	4	1
244	R:R:M207	R:R:P203	1.68	No	No	0	5	8
245	R:R:C192	R:R:I188	1.64	No	No	0	2	3
246	R:R:L202	R:R:P203	1.64	No	No	0	4	8
247	R:R:C253	R:R:I249	1.64	No	No	0	8	6
248	R:R:L326	R:R:P297	1.64	No	No	0	8	9
249	R:R:A177	R:R:I169	1.62	No	No	0	6	5
250	R:R:A208	R:R:K143	1.61	No	No	0	5	6
251	R:R:V286	R:R:V290	1.6	No	No	0	6	7
252	R:R:T69	R:R:V318	1.59	No	No	0	4	1
253	R:R:T251	R:R:V247	1.59	No	No	0	5	6
254	R:R:T251	R:R:V288	1.59	No	No	0	5	8
255	R:R:C332	R:R:L333	1.59	No	No	0	8	6
256	R:R:A119	R:R:N152	1.56	No	Yes	0	7	8
257	R:R:I73	R:R:V318	1.54	No	No	0	6	1
258	R:R:I79	R:R:V83	1.54	No	No	0	4	5
259	R:R:I310	R:R:V308	1.54	No	No	0	4	2
260	R:R:M67	R:R:S66	1.53	No	No	0	2	7
261	R:R:H173	R:R:P174	1.53	No	No	0	6	8
262	R:R:I68	R:R:T72	1.52	No	No	0	3	4
263	R:R:M266	R:R:V264	1.52	No	No	0	4	6
264	R:R:K211	R:R:T222	1.5	No	No	0	1	4
265	R:R:I140	R:R:I144	1.47	No	No	0	1	5
266	R:R:L221	R:R:T220	1.47	No	No	0	4	4
267	R:R:D274	R:R:S268	1.47	No	No	0	1	4
268	R:R:L285	R:R:T281	1.47	No	No	0	5	6
269	R:R:I244	R:R:L248	1.43	No	No	0	4	3
270	R:R:I280	R:R:L261	1.43	No	No	0	8	8
271	R:R:I236	R:R:N232	1.42	No	No	0	4	2
272	R:R:Q316	R:R:T313	1.42	Yes	No	0	3	3
273	R:R:G138	R:R:W135	1.41	No	Yes	0	7	8
274	R:R:L256	R:R:L259	1.38	No	No	0	5	2
275	R:R:R282	R:R:V286	1.31	No	No	0	5	6
276	R:R:V94	R:R:Y98	1.26	No	No	0	7	4
277	R:R:F322	R:R:L76	1.22	No	No	0	4	5
278	R:R:F206	R:R:L202	1.22	No	No	0	4	4
279	R:R:D218	R:R:R213	1.19	No	No	0	4	2

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y77	7.54	4	0	7
2	R:R:V91	3.985	4	0	9
3	R:R:Y108	6.524	5	0	7
4	R:R:F110	5.96	4	0	6
5	R:R:D116	7.015	4	0	9
6	R:R:L123	4.865	4	0	7
7	R:R:F125	6.6	4	2	6
8	R:R:W135	9.38429	7	2	8
9	R:R:F137	9.622	5	2	6
10	R:R:C142	5.115	4	2	9
11	R:R:D149	7.0825	4	6	5
12	R:R:Y151	5.47	5	3	5
13	R:R:N152	5.07	4	0	8
14	R:R:F154	6.736	5	0	6
15	R:R:T155	7.95	4	3	7
16	R:R:Y168	6.8575	4	0	8
17	R:R:W194	7.7525	4	3	9
18	R:R:F223	3.94667	6	0	6
19	R:R:W230	3.7625	4	0	1
20	R:R:F239	6.5225	4	1	6
21	R:R:F243	6.204	5	1	8
22	R:R:Y254	7.186	5	1	9
23	R:R:F291	5.475	4	1	9
24	R:R:W295	7.515	6	1	8
25	R:R:Q316	4.3975	4	0	3
26	R:R:W320	6.606	5	0	4
27	R:R:H321	9.5075	4	4	4
28	R:R:N330	7.42	4	1	9
29	R:R:N334	6.205	4	1	9
30	R:R:Y338	4.988	5	1	9
31	R:R:F340	3.95	4	0	6
32	R:R:F345	6.638	5	5	8
33	L:L:?1	8.31857	7	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:H321	R:R:W320	15.0862	6.35	Yes	Yes	0	4	4
2	R:R:C81	R:R:L123	12.5037	4.76	No	Yes	0	6	7
3	R:R:N88	R:R:P335	23.6451	4.89	No	No	0	9	9
4	R:R:D116	R:R:N88	26.4053	6.73	Yes	No	0	9	9
5	R:R:D116	R:R:N334	30.4567	8.08	Yes	Yes	0	9	9
6	R:R:N330	R:R:N334	90.5763	6.81	Yes	Yes	1	9	9
7	R:R:N330	R:R:W295	70.9056	10.17	Yes	Yes	1	9	8
8	R:R:M153	R:R:W295	100	5.82	No	Yes	0	7	8
9	L:L:?1	R:R:M153	97.9447	10.19	Yes	No	0	0	7
10	L:L:?1	R:R:W320	32.7311	4.56	Yes	Yes	0	0	4
11	R:R:F340	R:R:V91	16.5373	3.93	Yes	Yes	0	6	9
12	R:R:P335	R:R:V91	20.8375	3.53	No	Yes	0	9	9
13	R:R:F110	R:R:M92	17.9826	7.46	Yes	No	0	6	7
14	R:R:L114	R:R:M92	19.416	5.65	No	No	0	7	7
15	R:R:L114	R:R:W194	21.7675	3.42	No	Yes	0	7	9
16	R:R:N111	R:R:W194	40.7392	3.39	No	Yes	0	9	9
17	R:R:N111	R:R:N190	41.9712	9.54	No	No	0	9	7
18	R:R:N190	R:R:Y108	47.9536	10.47	No	Yes	0	7	7
19	R:R:M163	R:R:Y108	63.9993	3.59	No	Yes	0	9	7
20	R:R:M163	R:R:Y338	64.8759	4.79	No	Yes	0	9	9
21	R:R:N334	R:R:Y338	73.7073	5.81	Yes	Yes	1	9	9
22	R:R:F340	R:R:F349	10.632	4.29	Yes	No	0	6	6
23	R:R:F110	R:R:I95	13.6113	7.54	Yes	No	0	6	7
24	R:R:F345	R:R:I95	12.1187	5.02	Yes	No	0	8	7
25	R:R:D166	R:R:Y108	15.0684	6.9	No	Yes	0	8	7
26	R:R:W194	R:R:Y151	14.5649	9.65	Yes	Yes	3	9	5
27	R:R:D149	R:R:T122	42.0778	4.34	Yes	No	0	5	6
28	L:L:?1	R:R:D149	55.0909	10.87	Yes	Yes	0	0	5
29	R:R:T122	R:R:V145	40.8695	4.76	No	No	0	6	5
30	R:R:L123	R:R:Y328	15.791	7.03	Yes	No	0	7	7
31	R:R:V145	R:R:W135	30.2138	4.9	No	Yes	2	5	8
32	R:R:C142	R:R:W135	14.4465	6.53	Yes	Yes	2	9	8
33	L:L:?1	R:R:Y150	44.9683	15.02	Yes	No	0	0	4
34	R:R:L221	R:R:Y150	42.7471	3.52	No	No	0	4	4
35	R:R:F291	R:R:W295	27.0983	7.02	Yes	Yes	1	9	8
36	R:R:F291	R:R:I250	45.9515	6.28	Yes	No	1	9	8
37	R:R:I250	R:R:S164	14.6538	4.64	No	No	1	8	9
38	R:R:C253	R:R:S164	15.6311	3.44	No	No	0	8	9
39	R:R:I250	R:R:Y254	30.1901	3.63	No	Yes	1	8	9
40	R:R:R167	R:R:Y254	24.4625	8.23	No	Yes	0	9	9
41	R:R:M257	R:R:R167	23.2245	4.96	No	No	0	8	9
42	R:R:C253	R:R:Y168	12.5985	6.72	No	Yes	0	8	8
43	R:R:M257	R:R:V171	21.8385	7.61	No	No	0	8	8
44	R:R:L261	R:R:V171	20.4348	4.47	No	No	0	8	8
45	R:R:F223	R:R:L221	34.1349	3.65	Yes	No	0	6	4
46	R:R:F223	R:R:W230	19.4752	3.01	Yes	Yes	0	6	1
47	R:R:H299	R:R:W295	26.2631	8.46	No	Yes	1	7	8
48	R:R:F243	R:R:H299	18.024	10.18	Yes	No	1	8	7
49	R:R:L233	R:R:W230	10.7327	2.28	No	Yes	0	3	1
50	R:R:F243	R:R:T296	12.5037	7.78	Yes	No	0	8	5
51	R:R:I280	R:R:L261	10.3595	1.43	No	No	0	8	8
52	R:R:V287	R:R:Y338	10.7742	3.79	No	Yes	0	8	9
53	R:R:W320	R:R:Y301	12.4326	5.79	Yes	No	0	4	5
54	R:R:D149	R:R:Y328	16.946	9.2	Yes	No	6	5	7
55	R:R:F291	R:R:N330	20.8138	4.83	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:D149	R:R:T122	4.34	6	Yes	No	5	6	1	2
R:R:D149	R:R:Q126	3.92	6	Yes	No	5	6	1	2
R:R:Q126	R:R:Y328	5.64	6	No	No	6	7	2	2
R:R:D149	R:R:Y328	9.2	6	Yes	No	5	7	1	2
L:L:?1	R:R:D149	10.87	0	Yes	Yes	0	5	0	1
R:R:V204	R:R:Y150	6.31	0	No	No	5	4	2	1
R:R:L221	R:R:Y150	3.52	0	No	No	4	4	2	1
L:L:?1	R:R:Y150	15.02	0	Yes	No	0	4	0	1
R:R:F154	R:R:M153	3.73	0	Yes	No	6	7	2	1
R:R:M153	R:R:W295	5.82	0	No	Yes	7	8	1	2
L:L:?1	R:R:M153	10.19	0	Yes	No	0	7	0	1
R:R:F154	R:R:V238	7.87	0	Yes	No	6	5	2	1
L:L:?1	R:R:V238	4.77	0	Yes	No	0	5	0	1
L:L:?1	R:R:I298	6.86	0	Yes	No	0	6	0	1
R:R:W320	R:R:Y301	5.79	0	Yes	No	4	5	1	2
L:L:?1	R:R:V302	5.96	0	Yes	No	0	5	0	1
R:R:K305	R:R:W320	9.28	0	No	Yes	3	4	2	1
R:R:H321	R:R:W320	6.35	4	Yes	Yes	4	4	2	1
R:R:I324	R:R:W320	7.05	0	No	Yes	5	4	2	1
L:L:?1	R:R:W320	4.56	0	Yes	Yes	0	4	0	1
R:R:C323	R:R:I298	3.27	0	No	No	6	6	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8EF6_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.39
Number of Linked Nodes	267
Number of Links	279
Number of Hubs	33
Number of Links mediated by Hubs	129
Number of Communities	6
Number of Nodes involved in Communities	35
Number of Links involved in Communities	45

Path Summary
Number Of Nodes in MetaPath	56
Number Of Links MetaPath	55
Number of Shortest Paths	34361
Length Of Smallest Path	3
Average Path Length	12.8779
Length of Longest Path	30
Minimum Path Strength	1.43
Average Path Strength	6.19716
Maximum Path Strength	20.465
Minimum Path Correlation	0.7
Average Path Correlation	0.920653
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.34783
Average % Of Corr. Nodes	51.7928
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.6396
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	MOI
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	MOI
Name	Morphine
Synonyms	Morphine
Identifier
Formula	C17 H19 N O3
Molecular Weight	285.338
SMILES
PubChem	5288826
Formal Charge	0
Total Atoms	40
Total Chiral Atoms	5
Total Bonds	44
Total Aromatic Bonds	6


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P35372
Sequence	>8EF6_nogp_Chain_R S M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T K M K T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G T W P F G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H P V K A L D F R T P R N A K I I N V C N W I L S S A I G L P V M F M A T T K Y R Q G S I D C T L T F S H P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V R M L S G S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T I P E T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F K R C F R E F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	4DKL	A	Peptide	Opioid	μ	Mus musculus	β-Funaltrexamine	-	-	2.8	2012-03-21	doi.org/10.1038/nature10954
	5C1M	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.07	2015-08-05	doi.org/10.1038/nature14886
	6DDE	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-	Gi1/β1/γ2	3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDE (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-		3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDF	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-	Gi1/β1/γ2	3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-		3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	7SBF	A	Peptide	Opioid	μ	Mus musculus	PZM21	-	Gi1/β1/γ2	2.9	2022-04-20	doi.org/10.1002/anie.202200269
	7SBF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	PZM21	-		2.9	2022-04-20	doi.org/10.1002/anie.202200269
	7SCG	A	Peptide	Opioid	μ	Mus musculus	FH210	-	Gi1/β1/γ2	3	2022-04-20	doi.org/10.1002/anie.202200269
	7SCG (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	FH210	-		3	2022-04-20	doi.org/10.1002/anie.202200269
	7U2L	A	Peptide	Opioid	μ	Mus musculus	C5-guano	-	Gi1/β1/γ2	3.2	2022-05-04	doi.org/10.1038/s41586-022-05588-y
	7U2L (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	C5-guano	-		3.2	2022-05-04	doi.org/10.1038/s41586-022-05588-y
	7UL4	A	Peptide	Opioid	μ	Mus musculus	Alvimopan	-	-	2.8	2022-06-29	doi.org/10.1038/s41594-022-00859-8
	8EF5	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-	Gi1/β1/γ2	3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF5 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-		3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF6	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF6 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFB	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFB (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFL	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFL (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFO	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-	Gi1/β1/γ2	2.8	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFO (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-		2.8	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFQ	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Gi1/β1/γ2	3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFQ (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	7T2G	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-	Gi1/β1/γ2	2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2G (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-		2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2H	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-	Gi1/β1/γ2	2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2H (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-		2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7U2K	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-	Gi1/β1/γ2	3.3	2022-12-07	doi.org/10.1038/s41586-022-05588-y
	7U2K (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-		3.3	2022-12-07	doi.org/10.1038/s41586-022-05588-y
	8F7Q	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-	Gi1/β1/γ2	3.22	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7Q (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-		3.22	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7R	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Gi1/β1/γ2	3.28	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7R (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		3.28	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8K9K	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Gi3/β1/γ1	2.98	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9K (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.98	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9L	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	BMS-986122	Gi3/β1/γ1	3.05	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9L (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	BMS-986122		3.05	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	9BJK	A	Peptide	Opioid	μ	Mus musculus	Naloxone	PubChem 171642066	-	3.26	2024-07-17	doi.org/10.1038/s41586-024-07587-7
	9BQJ	A	Peptide	Opioid	μ	Mus musculus	RO76	-	Gi1/β1/γ2	3.3	2024-09-11	doi.org/10.1021/acscentsci.4c00525
	9BQJ (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	RO76	-		3.3	2024-09-11	doi.org/10.1021/acscentsci.4c00525
	9MQH	A	Peptide	Opioid	μ	Homo sapiens	-	-	-	3.9	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9MQI	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.3	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9MQJ	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.23	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9WST	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	chim(NtGi1-Gz)/β1/γ2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WST (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSV	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Arrestin2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSV (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSW	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	chim(NtGi1-Gz)/β1/γ2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSW (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSX	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Arrestin2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSX (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	8E0G	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.1	2023-10-18	doi.org/10.1186/s12915-023-01689-w
	8QOT	A	Peptide	Opioid	μ	Mus musculus	Nanobody-E	-	-	3.2	2023-12-27	doi.org/10.1101/2023.12.06.570395
	8Y72	A	Peptide	Opioid	μ	Homo sapiens	Peptide	BMS-986122	Gi1/β1/γ2	2.65	2025-08-06	To be published
	8Y72 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Peptide	BMS-986122		2.65	2025-08-06	To be published
	8Y73	A	Peptide	Opioid	μ	Homo sapiens	Peptide	MPAM-15	Gi1/β1/γ2	2.84	2025-08-06	To be published
	8Y73 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Peptide	MPAM-15		2.84	2025-08-06	To be published
	9PXU	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	Na	-	3.4	2025-11-12	10.1038/s41586-025-09677-6
	9PXV	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	-	Gi1/β1/γ2	3.02	2025-11-12	10.1038/s41586-025-09677-6
	9PXV (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	-		3.02	2025-11-12	10.1038/s41586-025-09677-6
	9PXW	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3.8	2025-11-12	10.1038/s41586-025-09677-6
	9PXW (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3.8	2025-11-12	10.1038/s41586-025-09677-6
	9PXX	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3.1	2025-11-12	10.1038/s41586-025-09677-6
	9PXX (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3.1	2025-11-12	10.1038/s41586-025-09677-6
	9PXY	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3	2025-11-12	10.1038/s41586-025-09677-6
	9PXY (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3	2025-11-12	10.1038/s41586-025-09677-6
	9PY2	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	3.16	2025-11-12	10.1038/s41586-025-09677-6
	9PY2 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		3.16	2025-11-12	10.1038/s41586-025-09677-6
	9PY3	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	3.2	2025-11-12	To be published
	9PY3 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		3.2	2025-11-12	To be published
	9PY4	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	2.78	2025-11-12	10.1038/s41586-025-09677-6
	9PY4 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		2.78	2025-11-12	10.1038/s41586-025-09677-6
	9ODJ	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg	Gi1/β1/γ2	3	2026-01-07	10.1038/s41586-025-10056-4
	9ODJ (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg		3	2026-01-07	10.1038/s41586-025-10056-4
	9ODK	A	Peptide	Opioid	μ	Mus musculus	-	GTP; Mg	Gi1/β1/γ2	3.9	2026-01-07	10.1038/s41586-025-10056-4
	9ODK (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	-	GTP; Mg		3.9	2026-01-07	10.1038/s41586-025-10056-4
	9ODL	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg	Gi1/β1/γ2	3.6	2026-01-07	10.1038/s41586-025-10056-4
	9ODL (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg		3.6	2026-01-07	10.1038/s41586-025-10056-4

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8EF6_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.