psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:P2	L:L:Y1	6.95	Yes	Yes	1	0	0
2	L:L:Y1	R:R:Y150	7.94	Yes	No	0	0	4
3	L:L:Y1	R:R:M153	7.18	Yes	Yes	1	0	7
4	L:L:Y1	R:R:V238	11.36	Yes	No	0	0	5
5	L:L:Y1	R:R:V302	3.79	Yes	No	1	0	5
6	L:L:P2	R:R:V302	3.53	Yes	No	1	0	5
7	L:L:P2	R:R:W320	6.76	Yes	Yes	1	0	4
8	L:L:P2	R:R:I324	6.77	Yes	Yes	1	0	5
9	L:L:W3	R:R:Q126	5.48	Yes	Yes	1	0	6
10	L:L:W3	R:R:W135	4.69	Yes	Yes	1	0	8
11	L:L:W3	R:R:V145	3.68	Yes	No	0	0	5
12	L:L:W3	R:R:I146	11.74	Yes	No	0	0	4
13	L:L:W3	R:R:C219	9.14	Yes	No	1	0	9
14	L:L:?5	L:L:F4	9.04	No	Yes	0	0	0
15	L:L:F4	R:R:Y77	4.13	Yes	Yes	1	0	7
16	L:L:F4	R:R:Q126	14.05	Yes	Yes	1	0	6
17	L:L:F4	R:R:Y130	6.19	Yes	No	1	0	5
18	L:L:F4	R:R:H321	6.79	Yes	Yes	1	0	4
19	L:L:F4	R:R:I324	3.77	Yes	Yes	1	0	5
20	L:L:?5	R:R:N129	13.59	No	No	0	0	4
21	R:R:I73	R:R:Y130	8.46	No	No	1	6	5
22	R:R:H321	R:R:I73	13.26	Yes	No	1	4	6
23	R:R:M74	R:R:S127	4.6	No	No	0	5	6
24	R:R:L131	R:R:M74	8.48	No	No	0	4	5
25	R:R:L123	R:R:Y77	7.03	Yes	Yes	0	7	7
26	R:R:H321	R:R:Y77	10.89	Yes	Yes	1	4	7
27	R:R:I324	R:R:Y77	8.46	Yes	Yes	1	5	7
28	R:R:C81	R:R:P124	3.77	No	No	0	6	8
29	R:R:C332	R:R:G84	3.92	No	No	0	8	8
30	R:R:F89	R:R:L85	3.65	No	No	0	4	6
31	R:R:L85	R:R:T120	4.42	No	No	0	6	5
32	R:R:D116	R:R:N88	6.73	Yes	No	0	9	9
33	R:R:A117	R:R:N88	4.69	No	No	0	7	9
34	R:R:N88	R:R:P335	4.89	No	No	0	9	9
35	R:R:F340	R:R:L90	3.65	Yes	No	0	6	6
36	R:R:P335	R:R:V91	3.53	No	Yes	0	9	9
37	R:R:A339	R:R:V91	5.09	No	Yes	0	6	9
38	R:R:F340	R:R:V91	3.93	Yes	Yes	0	6	9
39	R:R:F110	R:R:M92	7.46	Yes	No	0	6	7
40	R:R:L114	R:R:M92	5.65	No	No	0	7	7
41	R:R:R97	R:R:Y93	10.29	No	No	0	5	4
42	R:R:F110	R:R:I95	7.54	Yes	No	0	6	7
43	R:R:F345	R:R:I95	3.77	Yes	No	0	8	7
44	R:R:R97	R:R:V96	3.92	No	No	0	5	3
45	R:R:F352	R:R:Y98	16.5	No	No	0	7	4
46	R:R:N106	R:R:T99	5.85	No	No	0	8	6
47	R:R:F110	R:R:M101	8.71	Yes	No	0	6	7
48	R:R:N106	R:R:T103	7.31	No	No	0	8	7
49	R:R:R181	R:R:T105	5.17	Yes	No	0	7	8
50	R:R:F345	R:R:N106	7.25	Yes	No	0	8	8
51	R:R:T162	R:R:Y108	4.99	No	Yes	0	7	7
52	R:R:M163	R:R:Y108	3.59	No	Yes	0	9	7
53	R:R:D166	R:R:Y108	6.9	No	Yes	0	8	7
54	R:R:A186	R:R:Y108	5.34	No	Yes	0	7	7
55	R:R:N190	R:R:Y108	10.47	No	Yes	0	7	7
56	R:R:F345	R:R:I109	5.02	Yes	No	0	8	8
57	R:R:N111	R:R:N190	9.54	No	No	0	9	7
58	R:R:N111	R:R:W194	5.65	No	Yes	0	9	9
59	R:R:L112	R:R:T159	4.42	No	No	0	9	8
60	R:R:L112	R:R:Y338	3.52	No	Yes	0	9	9
61	R:R:L114	R:R:L118	4.15	No	No	0	7	7
62	R:R:L114	R:R:W194	4.56	No	Yes	0	7	9
63	R:R:D116	R:R:S156	7.36	Yes	No	0	9	9
64	R:R:D116	R:R:S331	7.36	Yes	No	0	9	9
65	R:R:D116	R:R:N334	8.08	Yes	Yes	0	9	9
66	R:R:L118	R:R:N152	13.73	No	Yes	0	7	8
67	R:R:D149	R:R:T122	11.56	No	No	0	5	6
68	R:R:L123	R:R:Y328	4.69	Yes	No	0	7	7
69	R:R:F125	R:R:W135	4.01	Yes	Yes	1	6	8
70	R:R:F125	R:R:F137	10.72	Yes	Yes	1	6	6
71	R:R:F125	R:R:L141	3.65	Yes	No	1	6	5
72	R:R:F125	R:R:V145	11.8	Yes	No	0	6	5
73	R:R:D149	R:R:Q126	3.92	No	Yes	1	5	6
74	R:R:Q126	R:R:Y328	10.15	Yes	No	1	6	7
75	R:R:F137	R:R:V128	6.55	Yes	No	0	6	3
76	R:R:N129	R:R:W135	7.91	No	Yes	0	4	8
77	R:R:H321	R:R:Y130	11.98	Yes	No	1	4	5
78	R:R:M132	R:R:P136	8.39	No	No	0	4	3
79	R:R:F137	R:R:W135	20.04	Yes	Yes	1	6	8
80	R:R:C142	R:R:W135	6.53	No	Yes	1	9	8
81	R:R:C219	R:R:W135	20.89	No	Yes	1	9	8
82	R:R:F137	R:R:P136	5.78	Yes	No	0	6	3
83	R:R:F137	R:R:L141	6.09	Yes	No	1	6	5
84	R:R:T139	R:R:T210	10.99	No	No	0	3	4
85	R:R:C142	R:R:C219	7.28	No	No	1	9	9
86	R:R:M205	R:R:S147	10.73	No	No	0	5	6
87	R:R:I148	R:R:N152	4.25	No	Yes	0	5	8
88	R:R:D149	R:R:Y328	8.05	No	No	1	5	7
89	R:R:V204	R:R:Y150	5.05	No	No	0	5	4
90	R:R:L221	R:R:Y150	3.52	No	No	0	4	4
91	R:R:N152	R:R:Y151	4.65	Yes	Yes	2	8	5
92	R:R:T155	R:R:Y151	7.49	Yes	Yes	2	7	5
93	R:R:W194	R:R:Y151	9.65	Yes	Yes	2	9	5
94	R:R:S197	R:R:Y151	3.82	No	Yes	2	8	5
95	R:R:G201	R:R:Y151	4.35	No	Yes	0	6	5
96	R:R:N152	R:R:T155	4.39	Yes	Yes	2	8	7
97	R:R:F154	R:R:M153	3.73	Yes	Yes	0	6	7
98	R:R:I157	R:R:M153	5.83	No	Yes	1	7	7
99	R:R:M153	R:R:W295	6.98	Yes	Yes	1	7	8
100	R:R:F154	R:R:F158	4.29	Yes	No	0	6	5
101	R:R:F154	R:R:I200	8.79	Yes	No	0	6	5
102	R:R:F154	R:R:V238	7.87	Yes	No	0	6	5
103	R:R:A242	R:R:F154	4.16	No	Yes	0	5	6
104	R:R:T155	R:R:W194	14.55	Yes	Yes	2	7	9
105	R:R:S197	R:R:T155	6.4	No	Yes	2	8	7
106	R:R:I157	R:R:W295	5.87	No	Yes	1	7	8
107	R:R:F158	R:R:N193	3.62	No	No	0	5	7
108	R:R:F158	R:R:S197	3.96	No	No	0	5	8
109	R:R:L160	R:R:N334	6.87	No	Yes	1	8	9
110	R:R:L160	R:R:Y338	7.03	No	Yes	1	8	9
111	R:R:C161	R:R:P246	3.77	No	No	0	7	8
112	R:R:N193	R:R:T162	7.31	No	No	0	7	7
113	R:R:M163	R:R:Y338	4.79	No	Yes	0	9	9
114	R:R:I250	R:R:S164	4.64	No	No	1	8	9
115	R:R:S164	R:R:Y254	10.17	No	Yes	1	9	9
116	R:R:D166	R:R:F180	5.97	No	Yes	0	8	3
117	R:R:D166	R:R:R181	11.91	No	Yes	0	8	7
118	R:R:R167	R:R:Y254	10.29	No	Yes	0	9	9
119	R:R:M257	R:R:R167	4.96	No	No	0	8	9
120	R:R:R167	R:R:Y338	5.14	No	Yes	0	9	9
121	R:R:C172	R:R:Y168	6.72	No	Yes	0	7	8
122	R:R:H173	R:R:Y168	4.36	No	Yes	0	6	8
123	R:R:C253	R:R:Y168	6.72	No	Yes	0	8	8
124	R:R:L256	R:R:Y168	7.03	No	Yes	0	5	8
125	R:R:F180	R:R:I169	13.82	Yes	No	0	3	5
126	R:R:A170	R:R:R181	5.53	No	Yes	0	8	7
127	R:R:M257	R:R:V171	7.61	No	No	4	8	8
128	R:R:L261	R:R:V171	5.96	Yes	No	4	8	8
129	R:R:F180	R:R:N185	4.83	Yes	No	3	3	4
130	R:R:F180	R:R:I189	3.77	Yes	No	3	3	5
131	R:R:I188	R:R:R184	6.26	No	No	0	3	3
132	R:R:I189	R:R:N185	7.08	No	No	3	5	4
133	R:R:L202	R:R:S198	4.5	No	No	0	4	4
134	R:R:F223	R:R:M207	4.98	Yes	No	0	6	5
135	R:R:T209	R:R:T222	7.85	No	No	0	5	4
136	R:R:I217	R:R:Y212	4.84	No	No	0	4	3
137	R:R:D218	R:R:R213	15.48	No	No	5	4	2
138	R:R:R213	R:R:T220	3.88	No	No	5	2	4
139	R:R:D218	R:R:T220	5.78	No	No	5	4	4
140	R:R:F223	R:R:L221	3.65	Yes	No	0	6	4
141	R:R:F223	R:R:W230	4.01	Yes	No	0	6	1
142	R:R:E231	R:R:F223	7	No	Yes	0	4	6
143	R:R:F223	R:R:L234	4.87	Yes	No	0	6	6
144	R:R:S224	R:R:W230	4.94	No	No	0	3	1
145	R:R:H225	R:R:P226	6.1	No	No	0	2	4
146	R:R:P226	R:R:W228	8.11	No	No	0	4	1
147	R:R:W228	R:R:Y229	5.79	No	No	0	1	1
148	R:R:W230	R:R:Y229	4.82	No	No	0	1	1
149	R:R:E231	R:R:K235	8.1	No	No	0	4	4
150	R:R:F239	R:R:F243	5.36	Yes	Yes	1	6	8
151	R:R:F239	R:R:I244	6.28	Yes	Yes	1	6	4
152	R:R:F239	R:R:H299	5.66	Yes	No	1	6	7
153	R:R:F239	R:R:I303	12.56	Yes	No	0	6	5
154	R:R:F241	R:R:I240	3.77	No	No	0	4	5
155	R:R:F243	R:R:I244	3.77	Yes	Yes	1	8	4
156	R:R:F243	R:R:V247	5.24	Yes	No	0	8	6
157	R:R:F243	R:R:T296	9.08	Yes	No	0	8	5
158	R:R:F243	R:R:H299	10.18	Yes	No	1	8	7
159	R:R:I292	R:R:V247	4.61	No	No	0	6	6
160	R:R:I250	R:R:Y254	3.63	No	Yes	1	8	9
161	R:R:F291	R:R:I250	7.54	No	No	1	9	8
162	R:R:V284	R:R:Y254	8.83	No	Yes	0	8	9
163	R:R:V288	R:R:Y254	3.79	No	Yes	0	8	9
164	R:R:L261	R:R:M257	4.24	Yes	No	4	8	8
165	R:R:I258	R:R:T281	6.08	Yes	No	0	5	6
166	R:R:I258	R:R:V284	4.61	Yes	No	0	5	8
167	R:R:K262	R:R:L259	4.23	No	No	0	4	2
168	R:R:R260	R:R:V264	3.92	No	No	0	5	6
169	R:R:L261	R:R:L267	4.15	Yes	Yes	0	8	1
170	R:R:L267	R:R:V264	7.45	Yes	No	0	1	6
171	R:R:L267	R:R:L277	8.3	Yes	No	0	1	6
172	R:R:G269	R:R:S268	3.71	No	No	0	1	4
173	R:R:K273	R:R:S270	6.12	No	No	0	3	2
174	R:R:E272	R:R:R275	9.3	No	No	0	3	4
175	R:R:N276	R:R:R279	9.64	No	No	0	5	7
176	R:R:I280	R:R:N276	4.25	No	No	0	8	5
177	R:R:E343	R:R:R279	4.65	No	No	0	5	7
178	R:R:L341	R:R:M283	9.9	No	No	0	7	8
179	R:R:L337	R:R:V290	7.45	No	No	0	8	7
180	R:R:F291	R:R:W295	7.02	No	Yes	1	9	8
181	R:R:F291	R:R:N330	3.62	No	Yes	1	9	9
182	R:R:C294	R:R:N330	9.45	No	Yes	0	9	9
183	R:R:H299	R:R:W295	8.46	No	Yes	1	7	8
184	R:R:G327	R:R:W295	4.22	No	Yes	0	7	8
185	R:R:N330	R:R:W295	9.04	Yes	Yes	1	9	8
186	R:R:C323	R:R:I298	4.91	No	No	0	6	6
187	R:R:Q316	R:R:Y301	6.76	Yes	No	0	3	5
188	R:R:S319	R:R:Y301	3.82	No	No	0	4	5
189	R:R:W320	R:R:Y301	5.79	Yes	No	0	4	5
190	R:R:K305	R:R:W320	11.6	No	Yes	0	3	4
191	R:R:I310	R:R:Q316	6.86	No	Yes	0	4	3
192	R:R:F322	R:R:V318	6.55	No	No	0	4	1
193	R:R:H321	R:R:W320	6.35	Yes	Yes	1	4	4
194	R:R:I324	R:R:W320	7.05	Yes	Yes	1	5	4
195	R:R:N330	R:R:N334	6.81	Yes	Yes	1	9	9
196	R:R:N334	R:R:Y338	5.81	Yes	Yes	1	9	9
197	R:R:F340	R:R:V336	3.93	Yes	No	0	6	6
198	R:R:D342	R:R:F345	9.55	No	Yes	0	8	8
199	R:R:E343	R:R:K346	10.8	No	No	0	5	8
200	R:R:P297	R:R:T296	3.5	No	No	0	9	5
201	R:R:C253	R:R:S164	3.44	No	No	0	8	9
202	R:R:A70	R:R:S66	3.42	No	No	0	4	7
203	L:L:P2	R:R:I298	3.39	Yes	No	0	0	6
204	R:R:A113	R:R:V91	3.39	No	Yes	0	9	9
205	R:R:I157	R:R:P246	3.39	No	No	0	7	8
206	R:R:C142	R:R:T210	3.38	No	No	0	9	4
207	R:R:A115	R:R:T155	3.36	No	Yes	0	8	7
208	R:R:F340	R:R:F349	3.22	Yes	No	0	6	6
209	R:R:A306	R:R:K235	3.21	No	No	0	4	4
210	R:R:S216	R:R:T134	3.2	No	No	0	1	5
211	R:R:T329	R:R:V80	3.17	No	No	0	5	7
212	R:R:C81	R:R:L85	3.17	No	No	0	6	6
213	R:R:C81	R:R:L123	3.17	No	Yes	0	6	7
214	R:R:C237	R:R:L233	3.17	No	No	0	5	3
215	R:R:A325	R:R:L76	3.15	No	No	0	6	5
216	R:R:T314	R:R:T69	3.14	No	No	0	1	4
217	R:R:I169	R:R:V165	3.07	No	No	0	5	6
218	R:R:I195	R:R:V191	3.07	No	No	0	4	4
219	R:R:I73	R:R:T69	3.04	No	No	0	6	4
220	R:R:I217	R:R:T134	3.04	No	No	0	4	5
221	R:R:I217	R:R:T210	3.04	No	No	0	4	4
222	R:R:I300	R:R:T296	3.04	No	No	0	6	5
223	R:R:K102	R:R:T103	3	No	No	0	7	7
224	R:R:K211	R:R:T222	3	No	No	0	1	4
225	R:R:L123	R:R:V80	2.98	Yes	No	0	7	7
226	R:R:L256	R:R:V252	2.98	No	No	0	5	4
227	R:R:L337	R:R:V287	2.98	No	No	0	8	8
228	R:R:N330	R:R:V290	2.96	Yes	No	0	9	7
229	R:R:I144	R:R:I148	2.94	No	No	0	5	5
230	R:R:I236	R:R:I240	2.94	No	No	0	4	5
231	R:R:I240	R:R:I244	2.94	No	Yes	0	5	4
232	R:R:I300	R:R:I304	2.94	No	No	0	6	5
233	R:R:I68	R:R:M67	2.92	No	No	0	3	2
234	R:R:I107	R:R:M101	2.92	No	No	0	5	7
235	R:R:I107	R:R:K187	2.91	No	No	0	5	2
236	R:R:I258	R:R:K262	2.91	Yes	No	0	5	4
237	R:R:I258	R:R:L285	2.85	Yes	No	0	5	5
238	R:R:I303	R:R:L307	2.85	No	No	0	5	5
239	R:R:L267	R:R:M266	2.83	Yes	No	0	1	4
240	R:R:Q316	R:R:T313	2.83	Yes	No	0	3	3
241	R:R:K346	R:R:L341	2.82	No	No	0	8	7
242	R:R:G138	R:R:W135	2.81	No	Yes	0	7	8
243	R:R:C237	R:R:F241	2.79	No	No	0	5	4
244	R:R:A177	R:R:R181	2.77	No	Yes	0	6	7
245	R:R:H321	R:R:T317	2.74	Yes	No	0	4	4
246	R:R:D342	R:R:N344	2.69	No	No	0	8	7
247	R:R:F345	R:R:V94	2.62	Yes	No	0	8	7
248	R:R:F349	R:R:V94	2.62	No	No	0	6	7
249	R:R:F223	R:R:T227	2.59	Yes	No	0	6	3
250	R:R:S127	R:R:Y77	2.54	No	Yes	0	6	7
251	R:R:F241	R:R:M245	2.49	No	No	0	4	5
252	R:R:F322	R:R:L76	2.44	No	No	0	4	5
253	R:R:F86	R:R:L90	2.44	No	No	0	5	6
254	R:R:E351	R:R:F352	2.33	No	No	0	3	7
255	R:R:R97	R:R:Y98	2.06	No	No	0	5	4
256	R:R:G201	R:R:S147	1.86	No	No	0	6	6
257	R:R:G84	R:R:T120	1.82	No	No	0	8	5
258	R:R:A104	R:R:A186	1.79	No	No	0	5	7
259	R:R:G133	R:R:M132	1.75	No	No	0	2	4
260	R:R:P183	R:R:T182	1.75	No	No	0	1	7
261	R:R:G87	R:R:L90	1.71	No	No	0	8	6
262	R:R:I107	R:R:P183	1.69	No	No	0	5	1
263	R:R:I310	R:R:P311	1.69	No	No	0	4	1
264	R:R:M207	R:R:P203	1.68	No	No	0	5	8
265	R:R:C192	R:R:I188	1.64	No	No	0	2	3
266	R:R:L202	R:R:P203	1.64	No	No	0	4	8
267	R:R:C253	R:R:I249	1.64	No	No	0	8	6
268	R:R:A208	R:R:I146	1.62	No	No	0	5	4
269	R:R:A208	R:R:K143	1.61	No	No	0	5	6
270	R:R:V286	R:R:V290	1.6	No	No	0	6	7
271	R:R:T69	R:R:V318	1.59	No	No	0	4	1
272	R:R:T251	R:R:V247	1.59	No	No	0	5	6
273	R:R:T251	R:R:V288	1.59	No	No	0	5	8
274	R:R:C332	R:R:L333	1.59	No	No	0	8	6
275	R:R:A119	R:R:N152	1.56	No	Yes	0	7	8
276	R:R:A306	R:R:N232	1.56	No	No	0	4	2
277	R:R:I79	R:R:V83	1.54	No	No	0	4	5
278	R:R:H173	R:R:P174	1.53	No	No	0	6	8
279	R:R:I68	R:R:T72	1.52	No	No	0	3	4
280	R:R:L307	R:R:V308	1.49	No	No	0	5	2
281	R:R:I140	R:R:I144	1.47	No	No	0	1	5
282	R:R:D274	R:R:S268	1.47	No	No	0	1	4
283	R:R:I244	R:R:L248	1.43	Yes	No	0	4	3
284	R:R:I280	R:R:L261	1.43	No	Yes	0	8	8
285	R:R:R260	R:R:S263	1.32	No	No	0	5	3
286	R:R:F110	R:R:V96	1.31	Yes	No	0	6	3
287	R:R:H173	R:R:K176	1.31	No	No	0	6	4
288	R:R:E312	R:R:Q316	1.27	No	Yes	0	2	3
289	R:R:F206	R:R:L202	1.22	No	No	0	4	4
290	R:R:R279	R:R:R282	1.07	No	No	0	7	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:Y1	7.444	5	1	0
2	L:L:P2	5.48	5	1	0
3	L:L:W3	6.946	5	1	0
4	L:L:F4	7.32833	6	1	0
5	R:R:Y77	6.61	5	1	7
6	R:R:V91	3.985	4	0	9
7	R:R:Y108	6.258	5	0	7
8	R:R:F110	6.255	4	0	6
9	R:R:D116	7.3825	4	0	9
10	R:R:L123	4.4675	4	0	7
11	R:R:F125	7.545	4	1	6
12	R:R:Q126	8.4	4	1	6
13	R:R:W135	9.55429	7	1	8
14	R:R:F137	9.836	5	1	6
15	R:R:Y151	5.992	5	2	5
16	R:R:N152	5.716	5	2	8
17	R:R:M153	5.93	4	1	7
18	R:R:F154	5.768	5	0	6
19	R:R:T155	7.238	5	2	7
20	R:R:Y168	6.2075	4	0	8
21	R:R:F180	7.0975	4	3	3
22	R:R:R181	6.345	4	0	7
23	R:R:W194	8.6025	4	2	9
24	R:R:F223	4.51667	6	0	6
25	R:R:F239	7.465	4	1	6
26	R:R:F243	6.726	5	1	8
27	R:R:I244	3.605	4	1	4
28	R:R:Y254	7.342	5	1	9
29	R:R:I258	4.1125	4	0	5
30	R:R:L261	3.945	4	4	8
31	R:R:L267	5.6825	4	0	1
32	R:R:W295	6.93167	6	1	8
33	R:R:Q316	4.43	4	0	3
34	R:R:W320	7.51	5	1	4
35	R:R:H321	8.66833	6	1	4
36	R:R:I324	6.5125	4	1	5
37	R:R:N330	6.376	5	1	9
38	R:R:N334	6.8925	4	1	9
39	R:R:Y338	5.258	5	1	9
40	R:R:F340	3.6825	4	0	6
41	R:R:F345	5.642	5	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:P2	L:L:Y1	100	6.95	Yes	Yes	1	0	0
2	L:L:Y1	R:R:Y150	26.9237	7.94	Yes	No	0	0	4
3	L:L:Y1	R:R:M153	80.9125	7.18	Yes	Yes	1	0	7
4	L:L:Y1	R:R:V238	35.3055	11.36	Yes	No	0	0	5
5	L:L:P2	R:R:I324	78.1448	6.77	Yes	Yes	1	0	5
6	L:L:F4	R:R:I324	61.8874	3.77	Yes	Yes	1	0	5
7	L:L:F4	R:R:Q126	42.5533	14.05	Yes	Yes	1	0	6
8	L:L:W3	R:R:Q126	39.3387	5.48	Yes	Yes	1	0	6
9	L:L:?5	L:L:F4	22.7887	9.04	No	Yes	0	0	0
10	L:L:?5	R:R:N129	21.6054	13.59	No	No	0	0	4
11	R:R:N129	R:R:W135	20.4451	7.91	No	Yes	0	4	8
12	L:L:P2	R:R:W320	19.8172	6.76	Yes	Yes	1	0	4
13	R:R:H321	R:R:W320	12.9014	6.35	Yes	Yes	1	4	4
14	R:R:I324	R:R:Y77	17.4901	8.46	Yes	Yes	1	5	7
15	R:R:L123	R:R:Y77	14.2294	7.03	Yes	Yes	0	7	7
16	R:R:C81	R:R:L123	10.5151	3.17	No	Yes	0	6	7
17	R:R:M153	R:R:W295	55.2378	6.98	Yes	Yes	1	7	8
18	R:R:N330	R:R:W295	26.0395	9.04	Yes	Yes	1	9	8
19	R:R:N330	R:R:N334	24.5406	6.81	Yes	Yes	1	9	9
20	R:R:D116	R:R:N334	15.462	8.08	Yes	Yes	0	9	9
21	R:R:D116	R:R:N88	13.0954	6.73	Yes	No	0	9	9
22	R:R:N88	R:R:P335	11.4979	4.89	No	No	0	9	9
23	R:R:P335	R:R:V91	10.7189	3.53	No	Yes	0	9	9
24	R:R:F154	R:R:M153	45.7384	3.73	Yes	Yes	0	6	7
25	R:R:F154	R:R:F158	77.5565	4.29	Yes	No	0	6	5
26	R:R:F158	R:R:S197	64.0634	3.96	No	No	0	5	8
27	R:R:S197	R:R:Y151	32.6201	3.82	No	Yes	2	8	5
28	R:R:W194	R:R:Y151	24.3796	9.65	Yes	Yes	2	9	5
29	R:R:L114	R:R:W194	45.7154	4.56	No	Yes	0	7	9
30	R:R:L114	R:R:M92	44.1179	5.65	No	No	0	7	7
31	R:R:F110	R:R:M92	42.0701	7.46	Yes	No	0	6	7
32	R:R:F154	R:R:V238	35.2168	7.87	Yes	No	0	6	5
33	R:R:S197	R:R:T155	30.5558	6.4	No	Yes	2	8	7
34	R:R:T155	R:R:W194	23.8076	14.55	Yes	Yes	2	7	9
35	R:R:F110	R:R:V96	13.2696	1.31	Yes	No	0	6	3
36	R:R:R97	R:R:V96	11.0311	3.92	No	No	0	5	3
37	R:R:F110	R:R:I95	17.4769	7.54	Yes	No	0	6	7
38	R:R:F345	R:R:I95	15.4488	3.77	Yes	No	0	8	7
39	R:R:F110	R:R:M101	11.2875	8.71	Yes	No	0	6	7
40	R:R:F158	R:R:N193	13.6377	3.62	No	No	0	5	7
41	R:R:N193	R:R:T162	12.6746	7.31	No	No	0	7	7
42	R:R:T162	R:R:Y108	12.0534	4.99	No	Yes	0	7	7
43	R:R:D166	R:R:Y108	12.8587	6.9	No	Yes	0	8	7
44	R:R:N334	R:R:Y338	17.0693	5.81	Yes	Yes	1	9	9
45	R:R:M163	R:R:Y338	10.7024	4.79	No	Yes	0	9	9
46	L:L:W3	R:R:W135	21.2372	4.69	Yes	Yes	1	0	8
47	R:R:F137	R:R:W135	14.9952	20.04	Yes	Yes	1	6	8
48	R:R:C142	R:R:W135	17.5525	6.53	No	Yes	1	9	8
49	R:R:C142	R:R:T210	22.6769	3.38	No	No	0	9	4
50	R:R:L221	R:R:Y150	24.5439	3.52	No	No	0	4	4
51	R:R:F291	R:R:W295	18.9561	7.02	No	Yes	1	9	8
52	R:R:F291	R:R:I250	19.6891	7.54	No	No	1	9	8
53	R:R:I250	R:R:Y254	12.2375	3.63	No	Yes	1	8	9
54	R:R:R167	R:R:Y254	14.775	10.29	No	Yes	0	9	9
55	R:R:R167	R:R:Y338	17.5196	5.14	No	Yes	0	9	9
56	R:R:M257	R:R:R167	21.9078	4.96	No	No	0	8	9
57	R:R:L261	R:R:M257	19.4195	4.24	Yes	No	4	8	8
58	R:R:F223	R:R:L221	23.4066	3.65	Yes	No	0	6	4
59	R:R:I217	R:R:T210	15.1431	3.04	No	No	0	4	4
60	R:R:H299	R:R:W295	23.926	8.46	No	Yes	1	7	8
61	R:R:F239	R:R:H299	10.423	5.66	Yes	No	1	6	7
62	R:R:F243	R:R:H299	12.6352	10.18	Yes	No	1	8	7
63	R:R:I240	R:R:I244	10.8438	2.94	No	Yes	0	5	4
64	R:R:I280	R:R:L261	10.4165	1.43	No	Yes	0	8	8
65	R:R:W320	R:R:Y301	10.755	5.79	Yes	No	0	4	5
66	R:R:M163	R:R:Y108	10.2127	3.59	No	Yes	0	9	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:Y1	R:R:Y150	7.94	1	Yes	No	0	4	0	1
L:L:Y1	R:R:M153	7.18	1	Yes	Yes	0	7	0	1
L:L:Y1	R:R:V238	11.36	1	Yes	No	0	5	0	1
L:L:Y1	R:R:V302	3.79	1	Yes	No	0	5	0	1
L:L:P2	R:R:V302	3.53	1	Yes	No	0	5	0	1
L:L:P2	R:R:W320	6.76	1	Yes	Yes	0	4	0	1
L:L:P2	R:R:I324	6.77	1	Yes	Yes	0	5	0	1
L:L:W3	R:R:Q126	5.48	1	Yes	Yes	0	6	0	1
L:L:W3	R:R:W135	4.69	1	Yes	Yes	0	8	0	1
L:L:W3	R:R:V145	3.68	1	Yes	No	0	5	0	1
L:L:W3	R:R:I146	11.74	1	Yes	No	0	4	0	1
L:L:W3	R:R:C219	9.14	1	Yes	No	0	9	0	1
L:L:F4	R:R:Y77	4.13	1	Yes	Yes	0	7	0	1
L:L:F4	R:R:Q126	14.05	1	Yes	Yes	0	6	0	1
L:L:F4	R:R:Y130	6.19	1	Yes	No	0	5	0	1
L:L:F4	R:R:H321	6.79	1	Yes	Yes	0	4	0	1
L:L:F4	R:R:I324	3.77	1	Yes	Yes	0	5	0	1
L:L:?5	R:R:N129	13.59	0	No	No	0	4	0	1
R:R:I73	R:R:Y130	8.46	1	No	No	6	5	2	1
R:R:H321	R:R:I73	13.26	1	Yes	No	4	6	1	2
R:R:L123	R:R:Y77	7.03	0	Yes	Yes	7	7	2	1
R:R:H321	R:R:Y77	10.89	1	Yes	Yes	4	7	1	1
R:R:I324	R:R:Y77	8.46	1	Yes	Yes	5	7	1	1
R:R:L123	R:R:Y328	4.69	0	Yes	No	7	7	2	2
R:R:F125	R:R:W135	4.01	1	Yes	Yes	6	8	2	1
R:R:F125	R:R:F137	10.72	1	Yes	Yes	6	6	2	2
R:R:F125	R:R:V145	11.8	1	Yes	No	6	5	2	1
R:R:D149	R:R:Q126	3.92	1	No	Yes	5	6	2	1
R:R:Q126	R:R:Y328	10.15	1	Yes	No	6	7	1	2
R:R:N129	R:R:W135	7.91	0	No	Yes	4	8	1	1
R:R:H321	R:R:Y130	11.98	1	Yes	No	4	5	1	1
R:R:F137	R:R:W135	20.04	1	Yes	Yes	6	8	2	1
R:R:C142	R:R:W135	6.53	1	No	Yes	9	8	2	1
R:R:C219	R:R:W135	20.89	1	No	Yes	9	8	1	1
R:R:C142	R:R:C219	7.28	1	No	No	9	9	2	1
R:R:D149	R:R:Y328	8.05	1	No	No	5	7	2	2
R:R:V204	R:R:Y150	5.05	0	No	No	5	4	2	1
R:R:L221	R:R:Y150	3.52	0	No	No	4	4	2	1
R:R:F154	R:R:M153	3.73	0	Yes	Yes	6	7	2	1
R:R:I157	R:R:M153	5.83	1	No	Yes	7	7	2	1
R:R:M153	R:R:W295	6.98	1	Yes	Yes	7	8	1	2
R:R:F154	R:R:V238	7.87	0	Yes	No	6	5	2	1
R:R:I157	R:R:W295	5.87	1	No	Yes	7	8	2	2
R:R:C323	R:R:I298	4.91	0	No	No	6	6	2	1
R:R:W320	R:R:Y301	5.79	1	Yes	No	4	5	1	2
R:R:K305	R:R:W320	11.6	0	No	Yes	3	4	2	1
R:R:H321	R:R:W320	6.35	1	Yes	Yes	4	4	1	1
R:R:I324	R:R:W320	7.05	1	Yes	Yes	5	4	1	1
L:L:P2	R:R:I298	3.39	1	Yes	No	0	6	0	1
R:R:G138	R:R:W135	2.81	0	No	Yes	7	8	2	1
R:R:H321	R:R:T317	2.74	1	Yes	No	4	4	1	2
R:R:S127	R:R:Y77	2.54	0	No	Yes	6	7	2	1
R:R:A208	R:R:I146	1.62	0	No	No	5	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8F7R_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.52
Number of Linked Nodes	267
Number of Links	290
Number of Hubs	41
Number of Links mediated by Hubs	157
Number of Communities	5
Number of Nodes involved in Communities	49
Number of Links involved in Communities	68

Path Summary
Number Of Nodes in MetaPath	67
Number Of Links MetaPath	66
Number of Shortest Paths	56533
Length Of Smallest Path	3
Average Path Length	13.7489
Length of Longest Path	27
Minimum Path Strength	1.42
Average Path Strength	6.20731
Maximum Path Strength	20.465
Minimum Path Correlation	0.7
Average Path Correlation	0.920516
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.7619
Average % Of Corr. Nodes	46.897
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.2788
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • Ras-like P-loop GTPases
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NH2
PDB Residues	L:L:?5
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P35372
Sequence	>8F7R_nogp_Chain_R S M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T K M K T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G T W P F G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H P V K A L D F R T P R N A K I I N V C N W I L S S A I G L P V M F M A T T K Y R Q G S I D C T L T F S H P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V R M L S G S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T I P E T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F K R C F R E F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	4DKL	A	Peptide	Opioid	μ	Mus musculus	β-Funaltrexamine	-	-	2.8	2012-03-21	doi.org/10.1038/nature10954
	5C1M	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.07	2015-08-05	doi.org/10.1038/nature14886
	6DDE	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-	Gi1/β1/γ2	3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDE (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-		3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDF	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-	Gi1/β1/γ2	3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	6DDF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	DAMGO	-		3.5	2018-06-13	doi.org/10.1038/s41586-018-0219-7
	7SBF	A	Peptide	Opioid	μ	Mus musculus	PZM21	-	Gi1/β1/γ2	2.9	2022-04-20	doi.org/10.1002/anie.202200269
	7SBF (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	PZM21	-		2.9	2022-04-20	doi.org/10.1002/anie.202200269
	7SCG	A	Peptide	Opioid	μ	Mus musculus	FH210	-	Gi1/β1/γ2	3	2022-04-20	doi.org/10.1002/anie.202200269
	7SCG (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	FH210	-		3	2022-04-20	doi.org/10.1002/anie.202200269
	7U2L	A	Peptide	Opioid	μ	Mus musculus	C5-guano	-	Gi1/β1/γ2	3.2	2022-05-04	doi.org/10.1038/s41586-022-05588-y
	7U2L (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	C5-guano	-		3.2	2022-05-04	doi.org/10.1038/s41586-022-05588-y
	7UL4	A	Peptide	Opioid	μ	Mus musculus	Alvimopan	-	-	2.8	2022-06-29	doi.org/10.1038/s41594-022-00859-8
	8EF5	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-	Gi1/β1/γ2	3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF5 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-		3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF6	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EF6 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFB	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFB (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFL	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-	Gi1/β1/γ2	3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFL (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-		3.2	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFO	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-	Gi1/β1/γ2	2.8	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFO (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-		2.8	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFQ	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Gi1/β1/γ2	3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	8EFQ (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		3.3	2022-11-09	doi.org/10.1016/j.cell.2022.09.041
	7T2G	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-	Gi1/β1/γ2	2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2G (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	-		2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2H	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-	Gi1/β1/γ2	2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7T2H (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-		2.5	2022-12-07	doi.org/10.1038/s41589-022-01208-y
	7U2K	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-	Gi1/β1/γ2	3.3	2022-12-07	doi.org/10.1038/s41586-022-05588-y
	7U2K (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-		3.3	2022-12-07	doi.org/10.1038/s41586-022-05588-y
	8F7Q	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-	Gi1/β1/γ2	3.22	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7Q (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	β-Endorphin	-		3.22	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7R	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Gi1/β1/γ2	3.28	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8F7R (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		3.28	2022-12-14	doi.org/10.1016/j.cell.2022.12.026
	8K9K	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Gi3/β1/γ1	2.98	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9K (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.98	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9L	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	BMS-986122	Gi3/β1/γ1	3.05	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	8K9L (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	BMS-986122		3.05	2024-05-29	doi.org/10.1038/s41467-024-47792-6
	9BJK	A	Peptide	Opioid	μ	Mus musculus	Naloxone	PubChem 171642066	-	3.26	2024-07-17	doi.org/10.1038/s41586-024-07587-7
	9BQJ	A	Peptide	Opioid	μ	Mus musculus	RO76	-	Gi1/β1/γ2	3.3	2024-09-11	doi.org/10.1021/acscentsci.4c00525
	9BQJ (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	RO76	-		3.3	2024-09-11	doi.org/10.1021/acscentsci.4c00525
	9MQH	A	Peptide	Opioid	μ	Homo sapiens	-	-	-	3.9	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9MQI	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.3	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9MQJ	A	Peptide	Opioid	μ	Homo sapiens	Isoquinuclidine	-	-	3.23	2025-02-12	doi.org/10.1101/2025.01.09.632033
	9WST	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	chim(NtGi1-Gz)/β1/γ2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WST (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSV	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-	Arrestin2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSV (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	DAMGO	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSW	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	chim(NtGi1-Gz)/β1/γ2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSW (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSX	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Arrestin2	2.8	2025-11-26	10.1038/s41422-025-01191-8
	9WSX (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-		2.8	2025-11-26	10.1038/s41422-025-01191-8
	8E0G	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.1	2023-10-18	doi.org/10.1186/s12915-023-01689-w
	8QOT	A	Peptide	Opioid	μ	Mus musculus	Nanobody-E	-	-	3.2	2023-12-27	doi.org/10.1101/2023.12.06.570395
	8Y72	A	Peptide	Opioid	μ	Homo sapiens	Peptide	BMS-986122	Gi1/β1/γ2	2.65	2025-08-06	To be published
	8Y72 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Peptide	BMS-986122		2.65	2025-08-06	To be published
	8Y73	A	Peptide	Opioid	μ	Homo sapiens	Peptide	MPAM-15	Gi1/β1/γ2	2.84	2025-08-06	To be published
	8Y73 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Peptide	MPAM-15		2.84	2025-08-06	To be published
	9PXU	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	Na	-	3.4	2025-11-12	10.1038/s41586-025-09677-6
	9PXV	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	-	Gi1/β1/γ2	3.02	2025-11-12	10.1038/s41586-025-09677-6
	9PXV (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	-		3.02	2025-11-12	10.1038/s41586-025-09677-6
	9PXW	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3.8	2025-11-12	10.1038/s41586-025-09677-6
	9PXW (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3.8	2025-11-12	10.1038/s41586-025-09677-6
	9PXX	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3.1	2025-11-12	10.1038/s41586-025-09677-6
	9PXX (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3.1	2025-11-12	10.1038/s41586-025-09677-6
	9PXY	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS	Gi1/β1/γ2	3	2025-11-12	10.1038/s41586-025-09677-6
	9PXY (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Naloxone	GDPβS		3	2025-11-12	10.1038/s41586-025-09677-6
	9PY2	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	3.16	2025-11-12	10.1038/s41586-025-09677-6
	9PY2 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		3.16	2025-11-12	10.1038/s41586-025-09677-6
	9PY3	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	3.2	2025-11-12	To be published
	9PY3 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		3.2	2025-11-12	To be published
	9PY4	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS	Gi1/β1/γ2	2.78	2025-11-12	10.1038/s41586-025-09677-6
	9PY4 (No Gprot)	A	Peptide	Opioid	μ	Homo sapiens	Loperamide	GDPβS		2.78	2025-11-12	10.1038/s41586-025-09677-6
	9ODJ	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg	Gi1/β1/γ2	3	2026-01-07	10.1038/s41586-025-10056-4
	9ODJ (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg		3	2026-01-07	10.1038/s41586-025-10056-4
	9ODK	A	Peptide	Opioid	μ	Mus musculus	-	GTP; Mg	Gi1/β1/γ2	3.9	2026-01-07	10.1038/s41586-025-10056-4
	9ODK (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	-	GTP; Mg		3.9	2026-01-07	10.1038/s41586-025-10056-4
	9ODL	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg	Gi1/β1/γ2	3.6	2026-01-07	10.1038/s41586-025-10056-4
	9ODL (No Gprot)	A	Peptide	Opioid	μ	Mus musculus	Mitragynine Pseudoindoxyl	GTP; Mg		3.6	2026-01-07	10.1038/s41586-025-10056-4

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