psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:V72	R:R:Y133	8.83	No	No	0	3	5
2	R:R:N73	R:R:P74	6.52	No	No	0	6	4
3	R:R:N73	R:R:W75	5.65	No	No	0	6	5
4	R:R:D76	R:R:N73	5.39	Yes	No	0	4	6
5	R:R:W75	R:R:Y312	7.72	No	No	0	5	4
6	R:R:D76	R:R:F129	9.55	Yes	Yes	0	4	7
7	R:R:D76	R:R:Y133	11.49	Yes	No	0	4	5
8	R:R:D76	R:R:Y312	6.9	Yes	No	0	4	4
9	R:R:L79	R:R:S82	3	Yes	Yes	1	6	5
10	R:R:F129	R:R:L79	7.31	Yes	Yes	1	7	6
11	R:R:L315	R:R:L79	4.15	No	Yes	0	5	6
12	R:R:L79	R:R:T319	2.95	Yes	No	1	6	6
13	R:R:G83	R:R:S82	3.71	No	Yes	0	6	5
14	R:R:I86	R:R:S82	3.1	Yes	Yes	1	7	5
15	R:R:S82	R:R:T319	3.2	Yes	No	1	5	6
16	R:R:I126	R:R:T84	4.56	No	No	0	7	5
17	R:R:M323	R:R:V85	3.04	No	No	0	6	4
18	R:R:I86	R:R:N90	5.66	Yes	No	1	7	9
19	R:R:D118	R:R:I86	4.2	No	Yes	1	9	7
20	R:R:I86	R:R:S322	9.29	Yes	No	1	7	9
21	R:R:D118	R:R:N90	6.73	No	No	1	9	9
22	R:R:N90	R:R:P326	8.15	No	No	0	9	9
23	R:R:L340	R:R:L92	4.15	No	No	0	6	7
24	R:R:A115	R:R:V93	3.39	No	Yes	0	9	9
25	R:R:F331	R:R:V93	3.93	Yes	Yes	0	6	9
26	R:R:L340	R:R:L96	4.15	No	No	0	6	8
27	R:R:I97	R:R:L103	2.85	No	No	4	8	9
28	R:R:F108	R:R:I97	3.77	Yes	No	4	9	8
29	R:R:I336	R:R:I97	2.94	No	No	4	8	8
30	R:R:S99	R:R:T100	3.2	No	Yes	0	4	6
31	R:R:P101	R:R:T100	3.5	No	Yes	0	5	6
32	R:R:L103	R:R:T100	7.37	No	Yes	0	9	6
33	R:R:F108	R:R:L103	10.96	Yes	No	4	9	9
34	R:R:P106	R:R:T105	5.25	No	No	0	6	7
35	R:R:F108	R:R:T105	5.19	Yes	No	0	9	7
36	R:R:P106	R:R:Y176	6.95	No	Yes	0	6	8
37	R:R:L182	R:R:P106	3.28	No	No	0	2	6
38	R:R:F108	R:R:N333	6.04	Yes	No	4	9	8
39	R:R:E335	R:R:F108	5.83	No	Yes	4	7	9
40	R:R:F108	R:R:I336	7.54	Yes	No	4	9	8
41	R:R:L110	R:R:S113	4.5	Yes	No	5	8	9
42	R:R:A161	R:R:L110	3.15	No	Yes	0	7	8
43	R:R:I162	R:R:L110	2.85	No	Yes	0	9	8
44	R:R:D165	R:R:L110	8.14	No	Yes	0	9	8
45	R:R:L110	R:R:V185	4.47	Yes	No	0	8	6
46	R:R:L110	R:R:L189	4.15	Yes	No	5	8	7
47	R:R:L189	R:R:S113	7.51	No	No	5	7	9
48	R:R:L114	R:R:S158	7.51	No	No	0	9	8
49	R:R:I162	R:R:L114	2.85	No	No	0	9	9
50	R:R:D118	R:R:S322	10.31	No	No	1	9	9
51	R:R:F147	R:R:L120	6.09	No	No	0	4	6
52	R:R:A121	R:R:S151	3.42	No	No	0	8	6
53	R:R:F147	R:R:G124	3.01	No	No	0	4	5
54	R:R:L125	R:R:L148	4.15	No	No	0	7	5
55	R:R:F131	R:R:L127	4.87	Yes	No	0	4	7
56	R:R:F129	R:R:H128	13.58	Yes	No	1	7	5
57	R:R:H128	R:R:Q132	9.89	No	Yes	1	5	5
58	R:R:H128	R:R:T144	9.58	No	No	0	5	5
59	R:R:F129	R:R:Q132	4.68	Yes	Yes	1	7	5
60	R:R:Q132	R:R:Y133	6.76	Yes	No	0	5	5
61	R:R:P136	R:R:V135	3.53	No	No	0	3	3
62	R:R:S137	R:R:V135	6.46	No	No	0	6	3
63	R:R:S137	R:R:V140	4.85	No	Yes	0	6	4
64	R:R:E138	R:R:T139	5.64	No	No	0	1	2
65	R:R:L142	R:R:N208	8.24	No	No	0	5	5
66	R:R:L142	R:R:P221	3.28	No	No	0	5	4
67	R:R:L143	R:R:V204	2.98	No	No	0	5	5
68	R:R:P221	R:R:V145	5.3	No	No	0	4	5
69	R:R:L222	R:R:V145	4.47	Yes	No	0	4	5
70	R:R:H226	R:R:V149	4.15	Yes	Yes	2	5	5
71	R:R:L230	R:R:V149	5.96	No	Yes	2	6	5
72	R:R:F152	R:R:S151	3.96	No	No	0	6	6
73	R:R:F152	R:R:W292	10.02	No	Yes	0	6	8
74	R:R:A154	R:R:W193	7.78	No	Yes	5	7	9
75	R:R:A154	R:R:S196	3.42	No	No	5	7	7
76	R:R:S155	R:R:V156	3.23	No	Yes	0	9	8
77	R:R:V156	R:R:V237	3.21	Yes	No	0	8	7
78	R:R:F288	R:R:V156	7.87	Yes	Yes	0	9	8
79	R:R:V156	R:R:W292	3.68	Yes	Yes	0	8	8
80	R:R:S157	R:R:T192	9.59	No	No	0	5	6
81	R:R:F288	R:R:L159	3.65	Yes	No	0	9	8
82	R:R:L159	R:R:N325	8.24	No	No	0	8	9
83	R:R:L159	R:R:Y329	3.52	No	Yes	0	8	9
84	R:R:L160	R:R:V237	5.96	No	No	0	6	7
85	R:R:I240	R:R:L160	5.71	No	No	0	5	6
86	R:R:I162	R:R:Y329	4.84	No	Yes	0	9	9
87	R:R:M241	R:R:T163	9.03	No	No	3	9	9
88	R:R:L244	R:R:T163	4.42	No	No	0	6	9
89	R:R:T163	R:R:Y245	8.74	No	Yes	3	9	9
90	R:R:L244	R:R:V164	2.98	No	No	0	6	6
91	R:R:D165	R:R:Y176	3.45	No	Yes	0	9	8
92	R:R:R166	R:R:Y245	6.17	No	Yes	3	9	9
93	R:R:R166	R:R:Y329	16.46	No	Yes	3	9	9
94	R:R:Y167	R:R:Y171	12.91	No	No	0	8	6
95	R:R:L244	R:R:Y167	4.69	No	No	0	6	8
96	R:R:S169	R:R:Y176	7.63	No	Yes	0	9	8
97	R:R:I248	R:R:L170	4.28	No	No	0	9	9
98	R:R:L170	R:R:V251	2.98	No	No	0	9	6
99	R:R:R247	R:R:Y171	11.32	No	No	0	6	6
100	R:R:V251	R:R:Y171	6.31	No	No	0	6	6
101	R:R:N172	R:R:T175	7.31	No	No	0	5	5
102	R:R:N172	R:R:T181	2.92	No	No	0	5	8
103	R:R:L174	R:R:T175	2.95	No	No	0	6	5
104	R:R:Y176	R:R:Y177	8.94	Yes	No	0	8	5
105	R:R:L182	R:R:R179	4.86	No	No	0	2	4
106	R:R:L183	R:R:R179	7.29	No	No	0	3	4
107	R:R:H186	R:R:L182	5.14	No	No	0	1	2
108	R:R:L188	R:R:T192	2.95	No	No	0	6	6
109	R:R:S196	R:R:W193	4.94	No	Yes	5	7	9
110	R:R:L201	R:R:V204	4.47	No	No	0	5	5
111	R:R:L202	R:R:P203	3.28	No	No	0	5	5
112	R:R:L202	R:R:W207	7.97	No	No	0	5	6
113	R:R:L222	R:R:P203	3.28	Yes	No	2	4	5
114	R:R:H226	R:R:P203	12.2	Yes	No	2	5	5
115	R:R:S225	R:R:W207	9.88	No	No	0	3	6
116	R:R:L210	R:R:N208	6.87	No	No	0	1	5
117	R:R:C209	R:R:C216	7.28	No	No	7	4	9
118	R:R:C209	R:R:R220	2.79	No	Yes	7	4	4
119	R:R:C216	R:R:R213	6.96	No	No	7	9	2
120	R:R:R213	R:R:R220	11.73	No	Yes	7	2	4
121	R:R:H304	R:R:R213	13.54	No	No	0	4	2
122	R:R:C216	R:R:R220	11.14	No	Yes	7	9	4
123	R:R:S217	R:R:V218	3.23	No	No	0	6	4
124	R:R:S217	R:R:V227	8.08	No	No	0	6	5
125	R:R:P221	R:R:R220	2.88	No	Yes	0	4	4
126	R:R:H226	R:R:L222	9	Yes	Yes	2	5	4
127	R:R:L222	R:R:V227	2.98	Yes	No	0	4	5
128	R:R:H226	R:R:L230	3.86	Yes	No	2	5	6
129	R:R:C299	R:R:V227	3.42	No	No	0	6	5
130	R:R:F234	R:R:F235	4.29	Yes	No	6	7	5
131	R:R:F234	R:R:F288	5.36	Yes	Yes	0	7	9
132	R:R:F234	R:R:W292	5.01	Yes	Yes	6	7	8
133	R:R:A296	R:R:F235	4.16	No	No	0	6	5
134	R:R:F238	R:R:F288	4.29	No	Yes	0	6	9
135	R:R:F238	R:R:G289	3.01	No	No	0	6	5
136	R:R:M241	R:R:Y245	3.59	No	Yes	3	9	9
137	R:R:F288	R:R:M241	3.73	Yes	No	0	9	9
138	R:R:H243	R:R:R247	10.16	No	No	0	3	6
139	R:R:L281	R:R:Y245	4.69	No	Yes	0	8	9
140	R:R:V284	R:R:Y245	7.57	No	Yes	3	8	9
141	R:R:L285	R:R:Y245	3.52	No	Yes	0	7	9
142	R:R:Y245	R:R:Y329	2.98	Yes	Yes	3	9	9
143	R:R:Q250	R:R:R247	4.67	No	No	0	3	6
144	R:R:C249	R:R:L281	6.35	No	No	0	6	8
145	R:R:H255	R:R:R254	6.77	No	No	0	8	4
146	R:R:H257	R:R:Q258	4.95	No	No	8	5	3
147	R:R:H257	R:R:L261	3.86	No	No	8	5	3
148	R:R:L261	R:R:Q258	6.65	No	No	8	3	3
149	R:R:K276	R:R:T274	4.5	No	No	0	8	7
150	R:R:R275	R:R:V278	3.92	No	No	0	5	7
151	R:R:I328	R:R:V283	4.61	No	No	0	9	7
152	R:R:I328	R:R:V284	3.07	No	No	3	9	8
153	R:R:V284	R:R:Y329	3.79	No	Yes	3	8	9
154	R:R:N321	R:R:T287	2.92	Yes	No	0	9	7
155	R:R:I324	R:R:T287	4.56	No	No	0	6	7
156	R:R:S291	R:R:W292	3.71	No	Yes	6	8	8
157	R:R:N321	R:R:S291	8.94	Yes	No	6	9	8
158	R:R:F295	R:R:W292	9.02	Yes	Yes	0	6	8
159	R:R:A318	R:R:W292	7.78	No	Yes	0	7	8
160	R:R:N321	R:R:W292	5.65	Yes	Yes	6	9	8
161	R:R:P294	R:R:T314	5.25	No	No	0	9	6
162	R:R:C299	R:R:F295	2.79	No	Yes	0	6	6
163	R:R:F295	R:R:L315	8.53	Yes	No	0	6	5
164	R:R:G302	R:R:Y298	2.9	No	Yes	0	4	4
165	R:R:D306	R:R:Y298	4.6	No	Yes	0	1	4
166	R:R:Y298	R:R:Y310	6.95	Yes	No	0	4	3
167	R:R:T311	R:R:Y298	4.99	No	Yes	0	4	4
168	R:R:E305	R:R:S303	7.19	No	No	0	3	3
169	R:R:E305	R:R:H304	23.39	No	No	0	3	4
170	R:R:D306	R:R:P307	3.22	No	No	0	1	4
171	R:R:P307	R:R:Y310	15.3	No	No	0	4	3
172	R:R:V309	R:R:Y310	7.57	No	No	0	3	3
173	R:R:L316	R:R:P317	3.28	No	No	0	5	7
174	R:R:L316	R:R:T319	4.42	No	No	0	5	6
175	R:R:L316	R:R:Y320	4.69	No	No	0	5	4
176	R:R:N321	R:R:N325	9.54	Yes	No	0	9	9
177	R:R:F331	R:R:I327	5.02	Yes	No	0	6	5
178	R:R:I328	R:R:Y329	7.25	No	Yes	3	9	9
179	R:R:E335	R:R:N333	3.94	No	No	4	7	8
180	R:R:I336	R:R:N333	2.83	No	No	4	8	8
181	R:R:E335	R:R:Q334	5.1	No	No	0	7	4
182	R:R:L343	R:R:L96	2.77	No	No	0	7	8
183	R:R:D165	R:R:M107	2.77	No	No	0	9	8
184	R:R:L183	R:R:L187	2.77	No	No	0	3	3
185	R:R:L199	R:R:L229	2.77	No	No	0	5	5
186	R:R:A308	R:R:Y312	2.67	No	No	0	1	4
187	R:R:F131	R:R:V130	2.62	Yes	No	0	4	5
188	R:R:F131	R:R:V140	2.62	Yes	Yes	0	4	4
189	R:R:F295	R:R:V219	2.62	Yes	No	0	6	4
190	R:R:R332	R:R:T280	2.59	No	No	0	7	9
191	R:R:F295	R:R:T314	2.59	Yes	No	0	6	6
192	R:R:H226	R:R:L199	2.57	Yes	No	0	5	5
193	R:R:T314	R:R:Y298	2.5	No	Yes	0	6	4
194	R:R:F331	R:R:L92	2.44	Yes	No	0	6	7
195	R:R:F129	R:R:L125	2.44	Yes	No	0	7	7
196	R:R:F152	R:R:L125	2.44	No	No	0	6	7
197	R:R:F131	R:R:L134	2.44	Yes	No	0	4	5
198	R:R:F234	R:R:L293	2.44	Yes	No	6	7	4
199	R:R:F235	R:R:L293	2.44	No	No	6	5	4
200	R:R:L168	R:R:Y167	2.34	No	No	0	5	8
201	R:R:E89	R:R:F331	2.33	No	Yes	0	8	6
202	R:R:L78	R:R:W75	2.28	No	No	0	6	5
203	R:R:L189	R:R:W193	2.28	No	Yes	5	7	9
204	R:R:L197	R:R:W193	2.28	No	Yes	0	3	9
205	R:R:L344	R:R:W341	2.28	No	No	0	6	3
206	R:R:G122	R:R:G83	2.11	No	No	0	8	6
207	R:R:G146	R:R:G200	2.11	No	No	2	6	6
208	R:R:A87	R:R:G88	1.95	No	No	0	6	4
209	R:R:A91	R:R:G88	1.95	No	No	0	4	4
210	R:R:A115	R:R:G112	1.95	No	No	0	9	6
211	R:R:A150	R:R:G200	1.95	No	No	0	5	6
212	R:R:G146	R:R:V149	1.84	No	Yes	2	6	5
213	R:R:G200	R:R:V149	1.84	No	Yes	2	6	5
214	R:R:G302	R:R:V301	1.84	No	No	0	4	4
215	R:R:A223	R:R:C209	1.81	No	No	0	5	4
216	R:R:A117	R:R:A154	1.79	No	No	0	8	7
217	R:R:P326	R:R:V93	1.77	No	Yes	0	9	9
218	R:R:G277	R:R:K276	1.74	No	No	0	8	8
219	R:R:G124	R:R:L148	1.71	No	No	0	5	5
220	R:R:A153	R:R:S196	1.71	No	No	0	5	7
221	R:R:G184	R:R:L187	1.71	No	No	0	6	3
222	R:R:A296	R:R:S231	1.71	No	No	0	6	4
223	R:R:G239	R:R:L242	1.71	No	No	0	3	4
224	R:R:C249	R:R:V252	1.71	No	No	0	6	8
225	R:R:G286	R:R:L285	1.71	No	No	0	5	7
226	R:R:A330	R:R:V93	1.7	No	Yes	0	8	9
227	R:R:A330	R:R:V111	1.7	No	No	0	8	7
228	R:R:G206	R:R:N208	1.7	No	No	0	4	5
229	R:R:A102	R:R:T100	1.68	No	Yes	0	6	6
230	R:R:A339	R:R:T100	1.68	No	Yes	0	7	6
231	R:R:A87	R:R:I126	1.62	No	No	0	6	7
232	R:R:S141	R:R:V140	1.62	No	Yes	0	9	4
233	R:R:V300	R:R:V301	1.6	No	No	9	5	4
234	R:R:T84	R:R:V81	1.59	No	No	0	5	4
235	R:R:T116	R:R:V94	1.59	No	No	0	6	7
236	R:R:C123	R:R:L127	1.59	No	No	0	4	7
237	R:R:T139	R:R:V140	1.59	No	Yes	0	2	4
238	R:R:A91	R:R:L119	1.58	No	No	0	4	7
239	R:R:I126	R:R:V130	1.54	No	No	0	7	5
240	R:R:I297	R:R:V300	1.54	No	No	9	5	5
241	R:R:I297	R:R:V301	1.54	No	No	9	5	4
242	R:R:A211	R:R:E212	1.51	No	No	0	3	3
243	R:R:L142	R:R:V204	1.49	No	No	0	5	5
244	R:R:L188	R:R:V164	1.49	No	No	0	6	6
245	R:R:L168	R:R:T181	1.47	No	No	0	5	8
246	R:R:P101	R:R:R104	1.44	No	No	0	5	8
247	R:R:Q132	R:R:S141	1.44	Yes	No	0	5	9
248	R:R:E89	R:R:V85	1.43	No	No	0	8	4
249	R:R:L242	R:R:L285	1.38	No	No	0	4	7
250	R:R:R179	R:R:S178	1.32	No	No	0	4	4
251	R:R:R180	R:R:S178	1.32	No	No	0	6	4
252	R:R:R224	R:R:S303	1.32	No	No	0	4	3
253	R:R:R332	R:R:V283	1.31	No	No	0	7	7
254	R:R:Q262	R:R:Q263	1.28	No	No	0	4	3
255	R:R:T116	R:R:W193	1.21	No	Yes	0	6	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:D76	8.3325	4	0	4
2	R:R:L79	4.3525	4	1	6
3	R:R:S82	3.2525	4	1	5
4	R:R:I86	5.5625	4	1	7
5	R:R:V93	2.6975	4	0	9
6	R:R:T100	3.486	5	0	6
7	R:R:F108	6.555	6	4	9
8	R:R:L110	4.54333	6	5	8
9	R:R:F129	7.512	5	1	7
10	R:R:F131	3.1375	4	0	4
11	R:R:Q132	5.6925	4	1	5
12	R:R:V140	2.67	4	0	4
13	R:R:V149	3.4475	4	2	5
14	R:R:V156	4.4975	4	0	8
15	R:R:Y176	6.7425	4	0	8
16	R:R:W193	3.698	5	5	9
17	R:R:R220	7.135	4	7	4
18	R:R:L222	4.9325	4	2	4
19	R:R:H226	6.356	5	2	5
20	R:R:F234	4.275	4	6	7
21	R:R:Y245	5.32286	7	3	9
22	R:R:F288	4.98	5	0	9
23	R:R:W292	6.41	7	6	8
24	R:R:F295	5.11	5	0	6
25	R:R:Y298	4.388	5	0	4
26	R:R:N321	6.7625	4	6	9
27	R:R:Y329	6.47333	6	3	9
28	R:R:F331	3.43	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D76	R:R:F129	18.8925	9.55	Yes	Yes	0	4	7
2	R:R:F129	R:R:Q132	36.8166	4.68	Yes	Yes	1	7	5
3	R:R:F129	R:R:L79	15.1352	7.31	Yes	Yes	1	7	6
4	R:R:L79	R:R:S82	37.1646	3	Yes	Yes	1	6	5
5	R:R:L315	R:R:L79	48.4618	4.15	No	Yes	0	5	6
6	R:R:I86	R:R:S82	32.7668	3.1	Yes	Yes	1	7	5
7	R:R:I126	R:R:V130	12.6841	1.54	No	No	0	7	5
8	R:R:F131	R:R:V130	14.4644	2.62	Yes	No	0	4	5
9	R:R:F131	R:R:V140	21.4848	2.62	Yes	Yes	0	4	4
10	R:R:S141	R:R:V140	31.7127	1.62	No	Yes	0	9	4
11	R:R:Q132	R:R:S141	33.3821	1.44	Yes	No	0	5	9
12	R:R:F331	R:R:V93	16.0178	3.93	Yes	Yes	0	6	9
13	R:R:P326	R:R:V93	24.5663	1.77	No	Yes	0	9	9
14	R:R:N90	R:R:P326	26.2457	8.15	No	No	0	9	9
15	R:R:I86	R:R:N90	27.7537	5.66	Yes	No	1	7	9
16	R:R:F108	R:R:T105	29.3323	5.19	Yes	No	0	9	7
17	R:R:P106	R:R:T105	31.5665	5.25	No	No	0	6	7
18	R:R:P106	R:R:Y176	51.0339	6.95	No	Yes	0	6	8
19	R:R:D165	R:R:Y176	57.4289	3.45	No	Yes	0	9	8
20	R:R:D165	R:R:L110	61.6149	8.14	No	Yes	0	9	8
21	R:R:I162	R:R:L110	87.6538	2.85	No	Yes	0	9	8
22	R:R:I162	R:R:Y329	93.4487	4.84	No	Yes	0	9	9
23	R:R:L159	R:R:Y329	100	3.52	No	Yes	0	8	9
24	R:R:F288	R:R:L159	68.1511	3.65	Yes	No	0	9	8
25	R:R:F288	R:R:V156	55.2955	7.87	Yes	Yes	0	9	8
26	R:R:V156	R:R:W292	56.3799	3.68	Yes	Yes	0	8	8
27	R:R:F152	R:R:W292	54.539	10.02	No	Yes	0	6	8
28	R:R:F152	R:R:L125	51.165	2.44	No	No	0	6	7
29	R:R:F129	R:R:L125	45.6072	2.44	Yes	No	0	7	7
30	R:R:F234	R:R:F288	55.2955	5.36	Yes	Yes	0	7	9
31	R:R:F234	R:R:W292	56.3799	5.01	Yes	Yes	6	7	8
32	R:R:L159	R:R:N325	34.5723	8.24	No	No	0	8	9
33	R:R:N321	R:R:N325	34.7034	9.54	Yes	No	0	9	9
34	R:R:N321	R:R:W292	35.5608	5.65	Yes	Yes	6	9	8
35	R:R:F108	R:R:L103	16.3052	10.96	Yes	No	4	9	9
36	R:R:L103	R:R:T100	14.066	7.37	No	Yes	0	9	6
37	R:R:L182	R:R:P106	18.4184	3.28	No	No	0	2	6
38	R:R:L110	R:R:L189	20.698	4.15	Yes	No	5	8	7
39	R:R:L142	R:R:P221	12.4823	3.28	No	No	0	5	4
40	R:R:P221	R:R:V145	29.4785	5.3	No	No	0	4	5
41	R:R:L222	R:R:V145	30.9159	4.47	Yes	No	0	4	5
42	R:R:L222	R:R:V227	50.6254	2.98	Yes	No	0	4	5
43	R:R:C299	R:R:V227	55.114	3.42	No	No	0	6	5
44	R:R:C299	R:R:F295	56.5866	2.79	No	Yes	0	6	6
45	R:R:F295	R:R:L315	49.6167	8.53	Yes	No	0	6	5
46	R:R:H226	R:R:L222	13.4658	9	Yes	Yes	2	5	4
47	R:R:L189	R:R:W193	18.6252	2.28	No	Yes	5	7	9
48	R:R:L244	R:R:T163	30.7898	4.42	No	No	0	6	9
49	R:R:M241	R:R:T163	26.044	9.03	No	No	3	9	9
50	R:R:F288	R:R:M241	40.4731	3.73	Yes	No	0	9	9
51	R:R:M241	R:R:Y245	13.4557	3.59	No	Yes	3	9	9
52	R:R:L244	R:R:Y167	22.5842	4.69	No	No	0	6	8
53	R:R:Y167	R:R:Y171	12.3613	12.91	No	No	0	8	6
54	R:R:L182	R:R:R179	14.0357	4.86	No	No	0	2	4
55	R:R:P221	R:R:R220	15.9724	2.88	No	Yes	0	4	4
56	R:R:F295	R:R:T314	22.8112	2.59	Yes	No	0	6	6
57	R:R:T314	R:R:Y298	19.4119	2.5	No	Yes	0	6	4
58	R:R:F295	R:R:W292	94.8558	9.02	Yes	Yes	0	6	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8TYW_nogp

PDB Summary
PDB	8TYW_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.79
Number of Linked Nodes	233
Number of Links	255
Number of Hubs	28
Number of Links mediated by Hubs	115
Number of Communities	9
Number of Nodes involved in Communities	52
Number of Links involved in Communities	66

Path Summary
Number Of Nodes in MetaPath	59
Number Of Links MetaPath	58
Number of Shortest Paths	41603
Length Of Smallest Path	3
Average Path Length	14.0289
Length of Longest Path	29
Minimum Path Strength	1.32
Average Path Strength	4.96735
Maximum Path Strength	18.465
Minimum Path Correlation	0.7
Average Path Correlation	0.927491
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	42.9188
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	44.4453
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P46095
Sequence	>8TYW_nogp_Chain_R V N P W D V L L C V S G T V I A G E N A L V V A L I A S T P A L R T P M F V L V G S L A T A D L L A G C G L I L H F V F Q Y L V P S E T V S L L T V G F L V A S F A A S V S S L L A I T V D R Y L S L Y N A L T Y Y S R R T L L G V H L L L A A T W T V S L G L G L L P V L G W N C L A E R A A C S V V R P L A R S H V A L L S A A F F M V F G I M L H L Y V R I C Q V V W R H A H Q I A L Q Q H T R K G V G T L A V V L G T F G A S W L P F A I Y C V V G S H E D P A V Y T Y A T L L P A T Y N S M I N P I I Y A F R N Q E I Q R A L W L L L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8TB0	A	Orphan	Orphan	GPR61	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.47	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8TB0 (No Gprot)	A	Orphan	Orphan	GPR61	Homo sapiens	-	-		3.47	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8TB7	A	Orphan	Orphan	GPR61	Homo sapiens	-	PubChem 168510218	-	2.94	2023-10-04	doi.org/10.1038/s41467-023-41646-3
	8KGK	A	Orphan	Orphan	GPR61	Homo sapiens	-	-	Gs/β1/γ2	3.16	2023-10-11	doi.org/10.1038/s41467-023-41654-3
	8KGK (No Gprot)	A	Orphan	Orphan	GPR61	Homo sapiens	-	-		3.16	2023-10-11	doi.org/10.1038/s41467-023-41654-3
	8T1V	A	Orphan	Orphan	GPR6	Homo sapiens	PubChem 118310209	Na	-	2.6	2024-12-04	doi.org/10.1126/scisignal.ado8741
	8T1W	A	Orphan	Orphan	GPR6	Homo sapiens	CVN424	-	-	3.49	2024-12-04	doi.org/10.1126/scisignal.ado8741
	8TF5	A	Orphan	Orphan	GPR6	Homo sapiens	Oleic acid	-	-	2.1	2024-12-04	doi.org/10.2210/pdb8TF5/pdb
	8TYW	A	Orphan	Orphan	GPR6	Homo sapiens	-	-	Gs/β1/γ2	3.43	2024-12-04	doi.org/10.2210/pdb8TF5/pdb
	8TYW (No Gprot)	A	Orphan	Orphan	GPR6	Homo sapiens	-	-		3.43	2024-12-04	doi.org/10.2210/pdb8TF5/pdb
	9BHL	A	Orphan	Orphan	GPR65	Homo sapiens	-	-	Gs/β1	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BHL (No Gprot)	A	Orphan	Orphan	GPR65	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BHM	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	Gs/β1	2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BHM (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BI6	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BI6 (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		2.9	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	8Z3O	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	-	3.3	2025-04-23	To be published
	8Z5H	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-04-23	To be published
	8Z5H (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		3.3	2025-04-23	To be published
	8Z68	A	Orphan	Orphan	GPR68	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.64	2025-04-23	To be published
	8Z68 (No Gprot)	A	Orphan	Orphan	GPR68	Homo sapiens	-	-		2.64	2025-04-23	To be published
	9JFT	A	Orphan	Orphan	GPR65	Homo sapiens	-	-	Gs/β1/γ2	3.27	2025-08-13	doi.org/10.1038/s41422-025-01092-w
	9JFT (No Gprot)	A	Orphan	Orphan	GPR65	Homo sapiens	-	-		3.27	2025-08-13	doi.org/10.1038/s41422-025-01092-w

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8TYW_nogp.zip

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