psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:G32	R:R:P33	4.06	No	No	0	3	4
2	R:R:L37	R:R:P38	3.28	No	No	0	1	4
3	R:R:G104	R:R:L37	5.13	No	No	0	3	1
4	R:R:P40	R:R:S39	3.56	No	No	0	3	2
5	R:R:D44	R:R:P40	4.83	No	No	9	4	3
6	R:R:F97	R:R:P40	7.22	Yes	No	9	5	3
7	R:R:A42	R:R:W43	2.59	No	No	0	4	3
8	R:R:V46	R:R:W43	3.68	No	No	0	4	3
9	R:R:W43	R:R:Y280	19.29	No	No	0	3	4
10	R:R:D44	R:R:F97	13.14	No	Yes	9	4	5
11	R:R:L284	R:R:V46	4.47	No	No	0	4	4
12	R:R:L47	R:R:L93	2.77	No	No	0	4	6
13	R:R:L284	R:R:L47	2.77	No	No	0	4	4
14	R:R:C48	R:R:F97	9.78	No	Yes	0	3	5
15	R:R:S50	R:R:T287	7.99	No	No	10	5	6
16	R:R:S50	R:R:Y288	2.54	No	No	10	5	4
17	R:R:G51	R:R:L93	3.42	No	No	0	5	6
18	R:R:T52	R:R:V94	6.35	No	No	0	4	6
19	R:R:L53	R:R:M291	4.24	No	No	0	4	5
20	R:R:D86	R:R:V54	4.38	Yes	No	0	9	7
21	R:R:M291	R:R:V54	3.04	No	No	0	5	7
22	R:R:L87	R:R:S55	3	No	No	0	7	6
23	R:R:E57	R:R:P294	3.14	No	No	0	8	9
24	R:R:E57	R:R:F299	9.33	No	Yes	0	8	5
25	R:R:A83	R:R:N58	4.69	No	Yes	0	9	9
26	R:R:D86	R:R:N58	16.16	Yes	Yes	11	9	9
27	R:R:L87	R:R:N58	4.12	No	Yes	0	7	9
28	R:R:N58	R:R:P294	6.52	Yes	No	11	9	9
29	R:R:L60	R:R:V61	2.98	No	No	0	7	9
30	R:R:A298	R:R:V61	3.39	No	No	0	7	9
31	R:R:F299	R:R:V61	3.93	Yes	No	0	5	9
32	R:R:F71	R:R:I64	2.51	Yes	Yes	6	8	8
33	R:R:I64	R:R:V304	3.07	Yes	No	6	8	8
34	R:R:I64	R:R:V307	3.07	Yes	No	6	8	8
35	R:R:I64	R:R:L308	4.28	Yes	No	0	8	5
36	R:R:G80	R:R:I65	3.53	No	No	0	6	7
37	R:R:G67	R:R:V66	5.52	No	No	0	5	4
38	R:R:R72	R:R:V66	2.62	No	No	0	8	4
39	R:R:P69	R:R:T68	3.5	No	No	0	5	7
40	R:R:F71	R:R:T68	9.08	Yes	No	0	8	7
41	R:R:F71	R:R:F76	12.86	Yes	Yes	0	8	9
42	R:R:D303	R:R:F71	4.78	No	Yes	0	7	8
43	R:R:F71	R:R:V304	6.55	Yes	No	6	8	8
44	R:R:F71	R:R:V307	3.93	Yes	No	6	8	8
45	R:R:A73	R:R:F76	2.77	No	Yes	0	7	9
46	R:R:P74	R:R:T149	3.5	No	No	0	5	8
47	R:R:F76	R:R:M75	3.73	Yes	No	0	9	8
48	R:R:M75	R:R:V79	3.04	No	No	0	8	7
49	R:R:F76	R:R:N301	4.83	Yes	No	0	9	8
50	R:R:L77	R:R:T153	2.95	No	No	0	4	6
51	R:R:I130	R:R:L78	7.14	No	No	0	9	8
52	R:R:L78	R:R:T153	4.42	No	No	0	8	6
53	R:R:S126	R:R:S81	4.89	No	No	0	8	9
54	R:R:L157	R:R:S81	3	No	No	0	7	9
55	R:R:S81	R:R:W161	6.18	No	Yes	0	9	9
56	R:R:I130	R:R:L82	2.85	No	No	1	9	9
57	R:R:L82	R:R:N293	6.87	No	No	0	9	9
58	R:R:L82	R:R:Y297	3.52	No	Yes	1	9	9
59	R:R:A85	R:R:W161	2.59	No	Yes	0	8	9
60	R:R:D86	R:R:S290	8.83	Yes	No	0	9	9
61	R:R:D86	R:R:P294	3.22	Yes	No	11	9	9
62	R:R:L88	R:R:M118	2.83	No	Yes	0	7	4
63	R:R:A119	R:R:L88	3.15	No	No	0	6	7
64	R:R:A89	R:R:F120	2.77	No	Yes	0	8	4
65	R:R:L91	R:R:L95	4.15	No	Yes	0	4	7
66	R:R:L116	R:R:L93	4.15	No	No	0	5	6
67	R:R:L95	R:R:V94	2.98	Yes	No	0	7	6
68	R:R:L112	R:R:L95	4.15	Yes	Yes	0	5	7
69	R:R:F97	R:R:V100	3.93	Yes	No	0	5	4
70	R:R:F101	R:R:F97	3.22	No	Yes	0	4	5
71	R:R:C102	R:R:F101	9.78	No	No	0	5	4
72	R:R:G104	R:R:I103	3.53	No	No	0	3	5
73	R:R:M108	R:R:S105	6.13	No	No	0	4	7
74	R:R:A106	R:R:E107	3.02	No	No	0	3	1
75	R:R:L112	R:R:M108	4.24	Yes	No	0	5	4
76	R:R:L110	R:R:N176	6.87	Yes	No	12	5	5
77	R:R:L110	R:R:L178	4.15	Yes	No	12	5	3
78	R:R:L110	R:R:P189	8.21	Yes	No	0	5	3
79	R:R:M118	R:R:V115	3.04	Yes	No	0	4	4
80	R:R:F120	R:R:L116	7.31	Yes	No	0	4	5
81	R:R:A164	R:R:M118	3.22	No	Yes	0	8	4
82	R:R:G168	R:R:M118	3.49	No	Yes	0	6	4
83	R:R:F120	R:R:S123	2.64	Yes	No	0	4	9
84	R:R:F120	R:R:W260	9.02	Yes	Yes	0	4	8
85	R:R:L167	R:R:T121	4.42	No	No	0	6	6
86	R:R:A122	R:R:W161	7.78	No	Yes	0	7	9
87	R:R:I124	R:R:S123	3.1	Yes	No	0	8	9
88	R:R:F256	R:R:I124	3.77	Yes	Yes	1	9	8
89	R:R:I124	R:R:W260	10.57	Yes	Yes	1	8	8
90	R:R:G125	R:R:V160	3.68	No	No	0	5	6
91	R:R:L127	R:R:M209	2.83	Yes	Yes	1	8	8
92	R:R:F256	R:R:L127	4.87	Yes	Yes	1	9	8
93	R:R:L127	R:R:N293	4.12	Yes	No	0	8	9
94	R:R:L127	R:R:Y297	10.55	Yes	Yes	1	8	9
95	R:R:L128	R:R:V205	7.45	No	No	1	7	8
96	R:R:I208	R:R:L128	2.85	No	No	0	5	7
97	R:R:L128	R:R:M209	4.24	No	Yes	1	7	8
98	R:R:A129	R:R:M156	4.83	No	No	0	6	5
99	R:R:I130	R:R:Y297	6.04	No	Yes	1	9	9
100	R:R:M209	R:R:T131	3.01	Yes	No	0	8	8
101	R:R:L212	R:R:T131	4.42	Yes	No	0	6	8
102	R:R:T131	R:R:Y213	9.99	No	Yes	0	8	9
103	R:R:L212	R:R:V132	4.47	Yes	No	0	6	6
104	R:R:V132	S:S:R218	2.62	No	No	0	6	4
105	R:R:D133	R:R:Y144	3.45	No	Yes	0	9	8
106	R:R:D133	R:R:R152	5.96	No	Yes	13	9	7
107	R:R:D133	R:R:M156	4.16	No	No	13	9	5
108	R:R:R134	R:R:Y213	4.12	No	Yes	0	9	9
109	R:R:Y135	R:R:Y139	5.96	Yes	No	0	8	6
110	R:R:L212	R:R:Y135	5.86	Yes	Yes	0	6	8
111	R:R:Q215	R:R:Y135	6.76	Yes	Yes	0	6	8
112	R:R:I216	R:R:Y135	3.63	No	Yes	0	9	8
113	R:R:Y135	S:S:Q215	9.02	Yes	Yes	0	8	6
114	R:R:L136	R:R:N140	5.49	No	No	0	5	5
115	R:R:L136	R:R:R152	10.93	No	Yes	0	5	7
116	R:R:L136	S:S:R218	3.64	No	No	0	5	4
117	R:R:S137	R:R:Y144	5.09	No	Yes	0	8	8
118	R:R:I216	R:R:L138	2.85	No	No	0	9	8
119	R:R:I219	R:R:L138	8.56	No	No	0	6	8
120	R:R:N140	R:R:Y139	3.49	No	No	0	5	6
121	R:R:Y139	S:S:I219	4.84	No	No	0	6	6
122	R:R:N140	S:S:R222	12.05	No	No	0	5	5
123	R:R:T143	S:S:R222	7.76	No	No	0	5	5
124	R:R:Y144	R:R:Y145	13.9	Yes	No	0	8	4
125	R:R:T149	R:R:Y144	2.5	No	Yes	0	8	8
126	R:R:E147	R:R:T148	4.23	No	No	0	5	6
127	R:R:R152	R:R:T149	6.47	Yes	No	0	7	8
128	R:R:V150	R:R:Y154	3.79	No	No	0	3	1
129	R:R:M156	R:R:R152	3.72	No	Yes	13	5	7
130	R:R:L165	R:R:L169	2.77	No	Yes	0	4	3
131	R:R:G166	R:R:L169	5.13	No	Yes	0	2	3
132	R:R:L167	R:R:L198	5.54	No	No	0	6	6
133	R:R:G168	R:R:P171	4.06	No	Yes	0	6	5
134	R:R:L169	R:R:L170	2.77	Yes	No	0	3	4
135	R:R:L169	R:R:L173	2.77	Yes	No	0	3	4
136	R:R:L170	R:R:P171	3.28	No	Yes	4	4	5
137	R:R:H194	R:R:L170	7.71	Yes	No	4	7	4
138	R:R:L190	R:R:P171	4.93	Yes	Yes	4	3	5
139	R:R:H194	R:R:P171	15.25	Yes	Yes	4	7	5
140	R:R:S191	R:R:W175	6.18	No	No	4	6	4
141	R:R:N193	R:R:W175	9.04	No	No	4	3	4
142	R:R:H194	R:R:W175	5.29	Yes	No	4	7	4
143	R:R:L178	R:R:N176	9.61	No	No	12	3	5
144	R:R:C177	R:R:C184	7.28	No	No	0	5	9
145	R:R:C177	R:R:P189	3.77	No	No	0	5	3
146	R:R:D179	R:R:L181	5.43	No	No	0	1	2
147	R:R:S191	R:R:T182	7.99	No	No	0	6	4
148	R:R:K192	R:R:T183	6.01	No	No	0	4	3
149	R:R:G185	R:R:K192	3.49	No	No	0	5	4
150	R:R:L195	R:R:V186	2.98	Yes	No	0	5	4
151	R:R:V186	R:R:Y266	5.05	No	Yes	0	4	3
152	R:R:L190	R:R:V187	5.96	Yes	No	4	3	5
153	R:R:L195	R:R:V187	4.47	Yes	No	4	5	5
154	R:R:P189	R:R:Y188	12.52	No	No	0	3	5
155	R:R:H194	R:R:L190	9	Yes	Yes	4	7	3
156	R:R:L190	R:R:L195	4.15	Yes	Yes	4	3	5
157	R:R:N193	R:R:S191	5.96	No	No	4	3	6
158	R:R:K192	R:R:V196	4.55	No	Yes	0	4	3
159	R:R:N193	S:S:L269	2.75	No	No	0	3	4
160	R:R:H194	R:R:L198	11.57	Yes	No	0	7	6
161	R:R:C267	R:R:L195	6.35	No	Yes	0	6	5
162	R:R:L268	R:R:V196	4.47	Yes	Yes	1	5	3
163	R:R:V196	S:S:L268	2.98	Yes	Yes	1	3	5
164	R:R:V196	S:S:L269	2.98	Yes	No	0	3	4
165	R:R:A199	R:R:L268	4.73	No	Yes	0	4	5
166	R:R:I200	S:S:F203	16.33	No	Yes	0	4	4
167	R:R:I200	S:S:L268	2.85	No	Yes	0	4	5
168	R:R:F202	R:R:F203	6.43	Yes	Yes	1	8	4
169	R:R:F202	R:R:F256	4.29	Yes	Yes	1	8	9
170	R:R:F202	R:R:W260	3.01	Yes	Yes	1	8	8
171	R:R:F202	R:R:T264	10.38	Yes	No	1	8	5
172	R:R:F203	R:R:L261	3.65	Yes	No	0	4	4
173	R:R:F203	R:R:T264	7.78	Yes	No	1	4	5
174	R:R:F203	S:S:I200	18.84	Yes	No	1	4	4
175	R:R:M204	S:S:F206	3.73	No	Yes	2	4	6
176	R:R:M204	S:S:L210	2.83	No	No	2	4	4
177	R:R:M209	R:R:V205	3.04	Yes	No	1	8	8
178	R:R:F206	R:R:L210	8.53	Yes	No	0	6	4
179	R:R:F206	R:R:F256	4.29	Yes	Yes	0	6	9
180	R:R:A257	R:R:F206	2.77	No	Yes	0	5	6
181	R:R:F206	S:S:M204	4.98	Yes	No	0	6	4
182	R:R:I208	S:S:Q211	4.12	No	Yes	0	5	2
183	R:R:F256	R:R:M209	6.22	Yes	Yes	1	9	8
184	R:R:Q211	R:R:Q215	2.56	Yes	Yes	0	2	6
185	R:R:Q211	S:S:I208	10.98	Yes	No	0	2	5
186	R:R:Q211	S:S:Q211	5.12	Yes	Yes	0	2	2
187	R:R:Q211	S:S:L212	9.32	Yes	No	0	2	6
188	R:R:L212	S:S:Q211	11.98	Yes	Yes	0	6	2
189	R:R:L249	R:R:Y213	3.52	No	Yes	0	7	9
190	R:R:V252	R:R:Y213	5.05	No	Yes	0	7	9
191	R:R:L253	R:R:Y213	11.72	No	Yes	0	7	9
192	R:R:Q215	R:R:R218	11.68	Yes	No	7	6	4
193	R:R:Q215	S:S:Y135	13.53	Yes	Yes	7	6	8
194	R:R:R218	S:S:Y135	8.23	No	Yes	7	4	8
195	R:R:R218	S:S:Y139	11.32	No	No	7	4	6
196	R:R:H223	R:R:I219	2.65	No	No	0	7	6
197	R:R:C221	R:R:Q225	3.05	No	No	0	6	6
198	R:R:A224	R:R:T242	5.03	No	No	0	5	7
199	R:R:I227	R:R:R231	2.51	No	No	0	7	4
200	R:R:I246	R:R:T242	3.04	No	No	0	7	7
201	R:R:V252	R:R:Y297	3.79	No	Yes	0	7	9
202	R:R:F256	R:R:W260	4.01	Yes	Yes	1	9	8
203	R:R:F256	R:R:N289	6.04	Yes	Yes	1	9	9
204	R:R:C259	R:R:P285	3.77	No	No	0	8	7
205	R:R:C259	R:R:N289	7.87	No	Yes	0	8	9
206	R:R:F263	R:R:W260	3.01	No	Yes	0	6	8
207	R:R:A286	R:R:W260	5.19	No	Yes	0	6	8
208	R:R:N289	R:R:W260	7.91	Yes	Yes	1	9	8
209	R:R:L261	R:R:V265	2.98	No	No	0	4	6
210	R:R:P262	R:R:T282	3.5	No	No	0	9	8
211	R:R:S274	R:R:Y266	3.82	No	Yes	0	3	3
212	R:R:Y266	R:R:Y278	9.93	Yes	Yes	0	3	3
213	R:R:T282	R:R:Y266	2.5	No	Yes	0	8	3
214	R:R:L268	S:S:V196	2.98	Yes	Yes	1	5	3
215	R:R:L268	S:S:I200	2.85	Yes	No	1	5	4
216	R:R:L268	S:S:L268	5.54	Yes	Yes	1	5	5
217	R:R:L269	S:S:V196	7.45	No	Yes	0	4	3
218	R:R:D271	R:R:S274	7.36	No	No	0	4	3
219	R:R:P275	R:R:Y278	6.95	No	Yes	0	3	3
220	R:R:L277	R:R:Y278	9.38	No	Yes	0	4	3
221	R:R:L277	R:R:Y280	3.52	No	No	0	4	4
222	R:R:T287	R:R:Y288	3.75	No	No	10	6	4
223	R:R:M291	R:R:Y288	3.59	No	No	0	5	4
224	R:R:N289	R:R:N293	5.45	Yes	No	0	9	9
225	R:R:F299	R:R:I295	3.77	Yes	No	0	5	5
226	R:R:I296	R:R:Y297	4.84	Yes	Yes	0	8	9
227	R:R:D303	R:R:N301	4.04	No	No	0	7	8
228	R:R:N301	R:R:V304	5.91	No	No	0	8	8
229	S:S:D44	S:S:P40	6.44	No	Yes	8	4	3
230	S:S:F97	S:S:P40	4.33	Yes	Yes	8	5	3
231	S:S:F101	S:S:P40	2.89	No	Yes	8	4	3
232	S:S:L277	S:S:W43	5.69	No	No	0	4	3
233	S:S:W43	S:S:Y280	2.89	No	No	0	3	4
234	S:S:D44	S:S:F97	11.94	No	Yes	8	4	5
235	S:S:D44	S:S:V100	2.92	No	No	0	4	4
236	S:S:F97	S:S:V45	2.62	Yes	No	0	5	5
237	S:S:L47	S:S:L93	5.54	No	No	0	4	6
238	S:S:C48	S:S:F97	16.76	No	Yes	0	3	5
239	S:S:S50	S:S:T287	4.8	No	No	0	5	6
240	S:S:S50	S:S:Y288	2.54	No	No	0	5	4
241	S:S:G51	S:S:L93	3.42	No	No	0	5	6
242	S:S:T52	S:S:V94	3.17	No	No	0	4	6
243	S:S:N58	S:S:V54	4.43	No	Yes	3	9	7
244	S:S:D86	S:S:V54	4.38	Yes	Yes	3	9	7
245	S:S:S290	S:S:V54	6.46	No	Yes	3	9	7
246	S:S:M291	S:S:V54	3.04	Yes	Yes	3	5	7
247	S:S:L91	S:S:S55	4.5	No	No	0	4	6
248	S:S:E57	S:S:M291	5.41	No	Yes	3	8	5
249	S:S:E57	S:S:P294	11	No	Yes	3	8	9
250	S:S:E57	S:S:I295	9.56	No	No	3	8	5
251	S:S:D86	S:S:N58	16.16	Yes	No	3	9	9
252	S:S:N58	S:S:P294	4.89	No	Yes	3	9	9
253	S:S:I65	S:S:V61	3.07	No	No	0	7	9
254	S:S:A298	S:S:V61	5.09	No	No	0	7	9
255	S:S:F299	S:S:V61	2.62	No	No	0	5	9
256	S:S:F299	S:S:I64	2.51	No	No	0	5	8
257	S:S:P69	S:S:T68	3.5	No	No	0	5	7
258	S:S:F71	S:S:T68	12.97	Yes	No	0	8	7
259	S:S:F71	S:S:F76	9.65	Yes	Yes	5	8	9
260	S:S:D303	S:S:F71	13.14	Yes	Yes	5	7	8
261	S:S:F71	S:S:V304	3.93	Yes	No	5	8	8
262	S:S:F71	S:S:V307	2.62	Yes	No	0	8	8
263	S:S:A73	S:S:F76	5.55	No	Yes	0	7	9
264	S:S:P74	S:S:V150	3.53	No	No	0	5	3
265	S:S:M75	S:S:V79	3.04	No	No	0	8	7
266	S:S:M75	S:S:R134	4.96	No	Yes	3	8	9
267	S:S:H238	S:S:M75	6.57	No	No	3	4	8
268	S:S:F76	S:S:N301	6.04	Yes	No	5	9	8
269	S:S:D303	S:S:F76	7.17	Yes	Yes	5	7	9
270	S:S:L77	S:S:Y154	4.69	No	No	0	4	1
271	S:S:L157	S:S:L77	2.77	No	No	0	7	4
272	S:S:A129	S:S:L78	3.15	No	No	0	6	8
273	S:S:I130	S:S:L78	4.28	Yes	No	0	9	8
274	S:S:D133	S:S:L78	5.43	No	No	0	9	8
275	S:S:I130	S:S:V79	3.07	Yes	No	0	9	7
276	S:S:S126	S:S:S81	3.26	No	No	0	8	9
277	S:S:L157	S:S:S81	4.5	No	No	14	7	9
278	S:S:S81	S:S:W161	8.65	No	Yes	14	9	9
279	S:S:L82	S:S:S126	3	No	No	0	9	8
280	S:S:A85	S:S:W161	2.59	No	Yes	0	8	9
281	S:S:D86	S:S:S290	10.31	Yes	No	3	9	9
282	S:S:D86	S:S:P294	3.22	Yes	Yes	3	9	9
283	S:S:L87	S:S:L91	6.92	No	No	0	7	4
284	S:S:A119	S:S:L88	3.15	No	No	0	6	7
285	S:S:L112	S:S:L95	4.15	No	No	0	5	7
286	S:S:H96	S:S:V100	4.15	Yes	No	0	5	4
287	S:S:H96	S:S:S109	4.18	Yes	No	0	5	8
288	S:S:H96	S:S:L112	6.43	Yes	No	0	5	5
289	S:S:H96	S:S:V113	2.77	Yes	No	0	5	4
290	S:S:F101	S:S:F97	6.43	No	Yes	8	4	5
291	S:S:C102	S:S:F101	9.78	No	No	0	5	4
292	S:S:E107	S:S:S105	7.19	No	No	15	1	7
293	S:S:M108	S:S:S105	6.13	No	No	15	4	7
294	S:S:A106	S:S:L178	3.15	No	Yes	0	3	3
295	S:S:E107	S:S:M108	2.71	No	No	15	1	4
296	S:S:L110	S:S:N176	4.12	No	No	0	5	5
297	S:S:L110	S:S:L178	5.54	No	Yes	0	5	3
298	S:S:P189	S:S:V113	8.84	No	No	0	3	4
299	S:S:G114	S:S:V172	5.52	No	No	0	5	5
300	S:S:M118	S:S:V115	4.56	Yes	No	0	4	4
301	S:S:F120	S:S:L116	4.87	No	No	0	4	5
302	S:S:L165	S:S:M118	8.48	No	Yes	0	4	4
303	S:S:G168	S:S:M118	3.49	No	Yes	0	6	4
304	S:S:L169	S:S:M118	5.65	No	Yes	0	3	4
305	S:S:F120	S:S:W260	10.02	No	Yes	2	4	8
306	S:S:A286	S:S:F120	2.77	No	No	2	6	4
307	S:S:A164	S:S:T121	5.03	No	No	0	8	6
308	S:S:L198	S:S:T121	2.95	No	No	0	6	6
309	S:S:A122	S:S:W161	6.48	No	Yes	0	7	9
310	S:S:G125	S:S:I124	3.53	No	Yes	0	5	8
311	S:S:F202	S:S:I124	5.02	Yes	Yes	2	8	8
312	S:S:F256	S:S:I124	3.77	Yes	Yes	2	9	8
313	S:S:I124	S:S:W260	8.22	Yes	Yes	2	8	8
314	S:S:G125	S:S:V160	3.68	No	No	0	5	6
315	S:S:L127	S:S:M209	2.83	Yes	Yes	0	8	8
316	S:S:L127	S:S:N293	4.12	Yes	No	0	8	9
317	S:S:L127	S:S:Y297	3.52	Yes	Yes	0	8	9
318	S:S:L128	S:S:V205	5.96	No	No	2	7	8
319	S:S:L128	S:S:M209	4.24	No	Yes	2	7	8
320	S:S:A129	S:S:M156	3.22	No	No	0	6	5
321	S:S:I130	S:S:R134	5.01	Yes	Yes	3	9	9
322	S:S:I130	S:S:Y297	6.04	Yes	Yes	3	9	9
323	S:S:M156	S:S:V132	3.04	No	No	0	5	6
324	S:S:L212	S:S:V132	4.47	No	No	0	6	6
325	S:S:H238	S:S:R134	4.51	No	Yes	3	4	9
326	S:S:R134	S:S:Y297	11.32	Yes	Yes	3	9	9
327	S:S:L136	S:S:Y135	3.52	No	Yes	0	5	8
328	S:S:Y135	S:S:Y139	3.97	Yes	No	7	8	6
329	S:S:L212	S:S:Y135	5.86	No	Yes	0	6	8
330	S:S:I216	S:S:Y135	3.63	No	Yes	0	9	8
331	S:S:L136	S:S:R152	7.29	No	No	0	5	7
332	S:S:H238	S:S:S137	9.76	No	No	0	4	8
333	S:S:I219	S:S:L138	4.28	No	No	0	6	8
334	S:S:L138	S:S:V240	13.41	No	No	0	8	4
335	S:S:N140	S:S:Y139	4.65	No	No	0	5	6
336	S:S:H223	S:S:L142	14.14	No	No	17	7	7
337	S:S:L142	S:S:Q226	3.99	No	No	17	7	5
338	S:S:E147	S:S:V150	2.85	No	No	0	5	3
339	S:S:R152	S:S:T149	9.06	No	No	0	7	8
340	S:S:L157	S:S:W161	4.56	No	Yes	14	7	9
341	S:S:V160	S:S:W161	3.68	No	Yes	0	6	9
342	S:S:L165	S:S:W161	7.97	No	Yes	0	4	9
343	S:S:G168	S:S:L167	3.42	No	No	0	6	6
344	S:S:L167	S:S:L198	2.77	No	No	0	6	6
345	S:S:L169	S:S:L173	2.77	No	No	0	3	4
346	S:S:L170	S:S:P171	8.21	No	No	0	4	5
347	S:S:P171	S:S:W175	5.4	No	No	0	5	4
348	S:S:H194	S:S:P171	15.25	Yes	No	0	7	5
349	S:S:L190	S:S:V172	2.98	Yes	No	16	3	5
350	S:S:H194	S:S:V172	4.15	Yes	No	16	7	5
351	S:S:N193	S:S:W175	7.91	No	No	0	3	4
352	S:S:D179	S:S:N176	6.73	No	No	0	1	5
353	S:S:C177	S:S:C184	7.28	No	No	0	5	9
354	S:S:D179	S:S:L178	2.71	No	Yes	0	1	3
355	S:S:L178	S:S:Y188	5.86	Yes	No	0	3	5
356	S:S:T182	S:S:T183	3.14	No	No	0	4	3
357	S:S:G185	S:S:K192	3.49	No	No	0	5	4
358	S:S:V186	S:S:Y266	15.14	No	Yes	0	4	3
359	S:S:S274	S:S:V186	3.23	Yes	No	0	3	4
360	S:S:L190	S:S:V187	4.47	Yes	No	0	3	5
361	S:S:L195	S:S:V187	4.47	No	No	0	5	5
362	S:S:P189	S:S:Y188	2.78	No	No	0	3	5
363	S:S:H194	S:S:L190	12.86	Yes	Yes	16	7	3
364	S:S:N193	S:S:S191	7.45	No	No	0	3	6
365	S:S:H194	S:S:L198	5.14	Yes	No	0	7	6
366	S:S:C267	S:S:L195	3.17	No	No	0	6	5
367	S:S:I200	S:S:V196	3.07	No	Yes	1	4	3
368	S:S:L268	S:S:V196	2.98	Yes	Yes	1	5	3
369	S:S:A199	S:S:L268	4.73	No	Yes	0	4	5
370	S:S:F202	S:S:F203	4.29	Yes	Yes	2	8	4
371	S:S:F202	S:S:F256	5.36	Yes	Yes	2	8	9
372	S:S:F202	S:S:W260	4.01	Yes	Yes	2	8	8
373	S:S:F202	S:S:L261	3.65	Yes	No	2	8	4
374	S:S:F202	S:S:T264	12.97	Yes	No	2	8	5
375	S:S:F203	S:S:L261	4.87	Yes	No	2	4	4
376	S:S:F203	S:S:T264	7.78	Yes	No	2	4	5
377	S:S:M209	S:S:V205	3.04	Yes	No	2	8	8
378	S:S:F206	S:S:L210	7.31	Yes	No	2	6	4
379	S:S:A257	S:S:F206	2.77	No	Yes	0	5	6
380	S:S:F256	S:S:M209	4.98	Yes	Yes	2	9	8
381	S:S:Q211	S:S:Q215	12.8	Yes	Yes	0	2	6
382	S:S:L249	S:S:Y213	4.69	No	No	0	7	9
383	S:S:A250	S:S:Y213	5.34	No	No	0	5	9
384	S:S:Q215	S:S:R218	15.19	Yes	No	0	6	4
385	S:S:I227	S:S:V220	3.07	No	Yes	0	7	8
386	S:S:V220	S:S:V240	3.21	Yes	No	0	8	4
387	S:S:I246	S:S:V220	7.68	No	Yes	0	7	8
388	S:S:H223	S:S:R222	3.39	No	No	0	7	5
389	S:S:H223	S:S:Q226	6.18	No	No	17	7	5
390	S:S:A224	S:S:Q225	3.03	No	No	0	5	6
391	S:S:Q226	S:S:Q230	5.12	No	No	0	5	4
392	S:S:L233	S:S:Q230	7.99	No	No	0	5	4
393	S:S:A241	S:S:Y239	5.34	No	No	0	6	4
394	S:S:K244	S:S:R243	8.66	No	No	0	8	5
395	S:S:I296	S:S:V252	4.61	No	No	3	8	7
396	S:S:V252	S:S:Y297	3.79	No	Yes	3	7	9
397	S:S:F256	S:S:W260	7.02	Yes	Yes	2	9	8
398	S:S:C259	S:S:N289	4.72	No	No	0	8	9
399	S:S:F263	S:S:W260	7.02	Yes	Yes	0	6	8
400	S:S:A286	S:S:W260	9.08	No	Yes	2	6	8
401	S:S:N289	S:S:W260	4.52	No	Yes	0	9	8
402	S:S:C267	S:S:F263	8.38	No	Yes	0	6	6
403	S:S:F263	S:S:T282	9.08	Yes	No	0	6	8
404	S:S:F263	S:S:L283	7.31	Yes	No	0	6	4
405	S:S:T279	S:S:Y266	7.49	No	Yes	0	4	3
406	S:S:T282	S:S:Y266	2.5	No	Yes	0	8	3
407	S:S:G270	S:S:S274	3.71	No	Yes	0	3	3
408	S:S:D271	S:S:H273	3.78	No	No	0	4	3
409	S:S:D271	S:S:S274	5.89	No	Yes	0	4	3
410	S:S:A272	S:S:H273	2.93	No	No	0	3	3
411	S:S:L284	S:S:Y288	10.55	No	No	0	4	4
412	S:S:N289	S:S:N293	9.54	No	No	0	9	9
413	S:S:I292	S:S:M291	2.92	No	Yes	0	5	5
414	S:S:I295	S:S:M291	2.92	No	Yes	3	5	5
415	S:S:I295	S:S:I296	2.94	No	No	3	5	8
416	S:S:I296	S:S:Y297	4.84	No	Yes	3	8	9
417	S:S:F299	S:S:L308	12.18	No	No	0	5	5
418	S:S:D303	S:S:N301	14.81	Yes	No	5	7	8
419	S:S:N301	S:S:V304	2.96	No	No	5	8	8
420	S:S:K306	S:S:Q302	2.71	No	No	0	5	5
421	S:S:D303	S:S:V304	5.84	Yes	No	5	7	8
422	S:S:L308	S:S:Q305	5.32	No	No	0	5	8
423	S:S:Q305	S:S:W309	14.24	No	No	0	8	4
424	S:S:K306	S:S:W309	3.48	No	No	0	5	4
425	S:S:V84	S:S:W161	2.45	No	Yes	0	6	9
426	R:R:F299	R:R:L308	2.44	Yes	No	0	5	5
427	S:S:F206	S:S:L261	2.44	Yes	No	2	6	4
428	R:R:Q226	R:R:R222	2.34	No	No	0	5	5
429	R:R:L281	R:R:Y278	2.34	No	Yes	0	4	3
430	R:R:M118	R:R:W161	2.33	Yes	Yes	0	4	9
431	S:S:K41	S:S:W43	2.32	No	No	0	3	3
432	R:R:G51	R:R:G90	2.11	No	No	0	5	7
433	R:R:G162	R:R:G163	2.11	No	No	0	3	3
434	S:S:G162	S:S:G163	2.11	No	No	0	3	3
435	S:S:C184	S:S:G185	1.96	No	No	0	9	5
436	R:R:A83	R:R:G80	1.95	No	No	0	9	6
437	R:R:P275	R:R:P276	1.95	No	No	0	3	2
438	S:S:A83	S:S:G80	1.95	No	No	0	9	6
439	S:S:A89	S:S:G90	1.95	No	No	0	8	7
440	S:S:A257	S:S:G254	1.95	No	No	0	5	4
441	S:S:P275	S:S:P276	1.95	No	No	0	3	2
442	S:S:C259	S:S:P285	1.88	No	No	0	8	7
443	R:R:A35	R:R:P36	1.87	No	No	0	2	5
444	R:R:A73	R:R:P74	1.87	No	No	0	7	5
445	S:S:A35	S:S:P36	1.87	No	No	0	2	5
446	S:S:A73	S:S:P74	1.87	No	No	0	7	5
447	S:S:A298	S:S:P294	1.87	No	Yes	0	7	9
448	R:R:G270	R:R:S274	1.86	No	No	0	3	3
449	S:S:G90	S:S:S55	1.86	No	No	0	7	6
450	R:R:G51	R:R:V94	1.84	No	No	0	5	6
451	R:R:G114	R:R:V113	1.84	No	No	0	5	4
452	R:R:G114	R:R:V172	1.84	No	No	0	5	5
453	S:S:G51	S:S:V54	1.84	No	Yes	0	5	7
454	S:S:G51	S:S:V94	1.84	No	No	0	5	6
455	S:S:G67	S:S:V66	1.84	No	No	0	5	4
456	R:R:G245	R:R:T248	1.82	No	No	0	8	8
457	S:S:C217	S:S:C221	1.82	No	No	0	6	6
458	S:S:G245	S:S:T242	1.82	No	No	0	8	7
459	S:S:C312	S:S:C313	1.82	No	No	0	5	4
460	S:S:A119	S:S:A89	1.79	No	No	0	6	8
461	S:S:P40	S:S:S39	1.78	Yes	No	0	3	2
462	S:S:P275	S:S:S274	1.78	No	Yes	0	3	3
463	R:R:P74	R:R:V150	1.77	No	No	0	5	3
464	S:S:P189	S:S:V187	1.77	No	No	0	3	5
465	R:R:G125	R:R:I124	1.76	No	Yes	0	5	8
466	R:R:G207	S:S:I208	1.76	No	No	0	4	5
467	R:R:I208	S:S:G207	1.76	No	No	0	5	4
468	S:S:G80	S:S:I65	1.76	No	No	0	6	7
469	S:S:G104	S:S:M108	1.75	No	No	0	3	4
470	S:S:P262	S:S:T282	1.75	No	No	0	9	8
471	R:R:G245	R:R:K244	1.74	No	No	0	8	8
472	S:S:G245	S:S:K244	1.74	No	No	0	8	8
473	S:S:C177	S:S:S191	1.72	No	No	0	5	6
474	R:R:G92	R:R:L112	1.71	No	Yes	0	4	5
475	R:R:G92	R:R:L116	1.71	No	No	0	4	5
476	R:R:A106	R:R:S109	1.71	No	No	0	3	8
477	S:S:A85	S:S:S123	1.71	No	No	0	8	9
478	S:S:G92	S:S:L91	1.71	No	No	0	4	4
479	S:S:G92	S:S:L112	1.71	No	No	0	4	5
480	S:S:G166	S:S:L165	1.71	No	No	0	2	4
481	S:S:C221	S:S:V220	1.71	No	Yes	0	6	8
482	S:S:G254	S:S:L253	1.71	No	No	0	4	7
483	R:R:A83	R:R:V62	1.7	No	No	0	9	7
484	S:S:A83	S:S:V62	1.7	No	No	0	9	7
485	R:R:C48	R:R:T52	1.69	No	No	0	3	4
486	S:S:C56	S:S:T52	1.69	No	No	0	4	4
487	R:R:A70	R:R:T68	1.68	No	No	0	6	7
488	R:R:D179	R:R:G180	1.68	No	No	0	1	3
489	R:R:A241	R:R:T242	1.68	No	No	0	6	7
490	S:S:A70	S:S:T68	1.68	No	No	0	6	7
491	S:S:D179	S:S:G180	1.68	No	No	0	1	3
492	S:S:L37	S:S:P38	1.64	No	No	0	1	4
493	S:S:L284	S:S:P285	1.64	No	No	0	4	7
494	R:R:A99	R:R:I103	1.62	No	No	0	4	5
495	R:R:V45	R:R:V46	1.6	No	No	0	5	4
496	R:R:S146	R:R:T143	1.6	No	No	0	4	5
497	R:R:S146	R:R:T148	1.6	No	No	0	4	6
498	R:R:V307	R:R:V311	1.6	No	No	0	8	5
499	S:S:V62	S:S:V66	1.6	No	No	0	7	4
500	S:S:V111	S:S:V115	1.6	No	No	0	4	4
501	S:S:V307	S:S:V311	1.6	No	No	0	8	5
502	R:R:T279	R:R:V186	1.59	No	No	0	4	4
503	R:R:T279	R:R:V187	1.59	No	No	0	4	5
504	R:R:C217	R:R:L249	1.59	No	No	0	6	7
505	S:S:T248	S:S:V251	1.59	No	No	0	8	6
506	R:R:A98	R:R:L95	1.58	No	Yes	0	5	7
507	R:R:A174	R:R:L173	1.58	No	No	0	4	4
508	R:R:A286	R:R:L283	1.58	No	No	0	6	4
509	S:S:A98	S:S:L95	1.58	No	No	0	5	7
510	S:S:A117	S:S:L190	1.58	No	Yes	0	4	3
511	R:R:I103	R:R:S105	1.55	No	No	0	5	7
512	R:R:I216	R:R:V220	1.54	No	No	0	9	8
513	R:R:I296	R:R:V251	1.54	Yes	No	0	8	6
514	S:S:I49	S:S:V45	1.54	No	No	0	4	5
515	S:S:I64	S:S:V307	1.54	No	No	0	8	8
516	S:S:A214	S:S:Q215	1.52	No	Yes	0	2	6
517	S:S:K192	S:S:T183	1.5	No	No	0	4	3
518	R:R:L110	R:R:V113	1.49	Yes	No	0	5	4
519	S:S:L249	S:S:V252	1.49	No	No	0	7	7
520	S:S:L269	S:S:V265	1.49	No	No	0	4	6
521	R:R:L142	R:R:T143	1.47	No	No	0	7	5
522	R:R:L249	R:R:T248	1.47	No	No	0	7	8
523	R:R:I292	R:R:I296	1.47	No	Yes	0	5	8
524	S:S:L77	S:S:T153	1.47	No	No	0	4	6
525	S:S:L127	S:S:T131	1.47	Yes	No	0	8	8
526	S:S:L142	S:S:T143	1.47	No	No	0	7	5
527	R:R:A272	R:R:H273	1.46	No	No	0	3	3
528	S:S:G245	S:S:Y239	1.45	No	No	0	8	4
529	R:R:E107	R:R:S105	1.44	No	No	0	1	7
530	R:R:I49	R:R:L53	1.43	No	No	0	4	4
531	S:S:I49	S:S:L53	1.43	No	No	0	4	4
532	R:R:E147	R:R:T151	1.41	No	No	0	5	4
533	S:S:A247	S:S:R243	1.38	No	No	0	8	5
534	R:R:D303	R:R:Q302	1.31	No	No	0	7	5
535	S:S:C312	S:S:W309	1.31	No	No	0	5	4
536	S:S:A174	S:S:W175	1.3	No	No	0	4	4
537	R:R:H96	R:R:L112	1.29	No	Yes	0	5	5
538	R:R:I219	R:R:R222	1.25	No	No	0	6	5
539	R:R:I296	R:R:R300	1.25	Yes	No	0	8	7
540	R:R:V84	R:R:W161	1.23	No	Yes	0	6	9
541	R:R:L77	R:R:R72	1.21	No	No	0	4	8
542	S:S:Q302	S:S:R231	1.17	No	No	0	5	4
543	S:S:Y266	S:S:Y278	0.99	Yes	No	0	3	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:N58	7.8725	4	11	9
2	R:R:I64	3.2325	4	6	8
3	R:R:F71	6.61833	6	6	8
4	R:R:F76	6.0475	4	0	9
5	R:R:D86	8.1475	4	11	9
6	R:R:L95	3.215	4	0	7
7	R:R:F97	7.458	5	9	5
8	R:R:L110	5.18	4	12	5
9	R:R:L112	2.8475	4	0	5
10	R:R:M118	2.982	5	0	4
11	R:R:F120	5.435	4	0	4
12	R:R:I124	4.8	4	1	8
13	R:R:L127	5.5925	4	1	8
14	R:R:Y135	6.246	5	0	8
15	R:R:Y144	6.235	4	0	8
16	R:R:R152	6.77	4	13	7
17	R:R:W161	4.022	5	0	9
18	R:R:L169	3.36	4	0	3
19	R:R:P171	6.88	4	4	5
20	R:R:L190	6.01	4	4	3
21	R:R:H194	9.764	5	4	7
22	R:R:L195	4.4875	4	4	5
23	R:R:V196	3.745	4	1	3
24	R:R:F202	6.0275	4	1	8
25	R:R:F203	9.175	4	1	4
26	R:R:F206	5.1425	4	0	6
27	R:R:M209	3.868	5	1	8
28	R:R:Q211	6.995	4	0	2
29	R:R:L212	6.6825	4	0	6
30	R:R:Y213	6.88	5	0	9
31	R:R:Q215	8.6325	4	7	6
32	R:R:F256	4.78429	7	1	9
33	R:R:W260	6.10286	7	1	8
34	R:R:Y266	5.325	4	0	3
35	R:R:L268	4.114	5	1	5
36	R:R:Y278	7.15	4	0	3
37	R:R:N289	6.8175	4	1	9
38	R:R:I296	2.275	4	0	8
39	R:R:Y297	5.748	5	1	9
40	R:R:F299	4.8675	4	0	5
41	S:S:P40	3.86	4	8	3
42	S:S:V54	4.03	5	3	7
43	S:S:F71	8.462	5	5	8
44	S:S:F76	7.1025	4	5	9
45	S:S:D86	8.5175	4	3	9
46	S:S:H96	4.3825	4	0	5
47	S:S:F97	8.416	5	8	5
48	S:S:M118	5.545	4	0	4
49	S:S:I124	5.135	4	2	8
50	S:S:L127	2.985	4	0	8
51	S:S:I130	4.6	4	3	9
52	S:S:R134	6.45	4	3	9
53	S:S:Y135	6.45667	6	7	8
54	S:S:W161	5.19714	7	14	9
55	S:S:L178	4.315	4	0	3
56	S:S:L190	5.4725	4	16	3
57	S:S:H194	9.35	4	16	7
58	S:S:V196	4.12	4	1	3
59	S:S:F202	5.88333	6	2	8
60	S:S:F203	8.3175	4	2	4
61	S:S:F206	4.0625	4	2	6
62	S:S:M209	3.7725	4	2	8
63	S:S:Q211	8.505	4	0	2
64	S:S:Q215	9.6325	4	0	6
65	S:S:V220	3.9175	4	0	8
66	S:S:F256	5.2825	4	2	9
67	S:S:W260	7.12714	7	2	8
68	S:S:F263	7.9475	4	0	6
69	S:S:Y266	6.53	4	0	3
70	S:S:L268	3.816	5	1	5
71	S:S:S274	3.6525	4	0	3
72	S:S:M291	3.5725	4	3	5
73	S:S:P294	5.245	4	3	9
74	S:S:Y297	5.902	5	3	9
75	S:S:D303	10.24	4	5	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:L112	R:R:M108	10.0545	4.24	Yes	No	0	5	4
2	R:R:L47	R:R:L93	10.5228	2.77	No	No	0	4	6
3	R:R:L116	R:R:L93	21.2181	4.15	No	No	0	5	6
4	R:R:G92	R:R:L116	15.5372	1.71	No	No	0	4	5
5	R:R:G92	R:R:L112	14.5932	1.71	No	Yes	0	4	5
6	R:R:F120	R:R:L116	36.5933	7.31	Yes	No	0	4	5
7	R:R:F120	R:R:W260	38.5624	9.02	Yes	Yes	0	4	8
8	R:R:F256	R:R:W260	13.8307	4.01	Yes	Yes	1	9	8
9	R:R:F256	R:R:M209	64.4453	6.22	Yes	Yes	1	9	8
10	R:R:M209	R:R:T131	63.054	3.01	Yes	No	0	8	8
11	R:R:L212	R:R:T131	64.2487	4.42	Yes	No	0	6	8
12	R:R:L212	R:R:V132	34.513	4.47	Yes	No	0	6	6
13	R:R:V132	S:S:R218	33.8571	2.62	No	No	0	6	4
14	R:R:L136	S:S:R218	58.6039	3.64	No	No	0	5	4
15	R:R:L136	R:R:R152	61.0113	10.93	No	Yes	0	5	7
16	R:R:R152	R:R:T149	53.6719	6.47	Yes	No	0	7	8
17	R:R:P74	R:R:T149	49.6405	3.5	No	No	0	5	8
18	R:R:A73	R:R:P74	46.5202	1.87	No	No	0	7	5
19	R:R:A73	R:R:F76	45.4741	2.77	No	Yes	0	7	9
20	R:R:F71	R:R:F76	37.872	12.86	Yes	Yes	0	8	9
21	R:R:F71	R:R:I64	28.0652	2.51	Yes	Yes	6	8	8
22	R:R:I64	R:R:L308	27.1226	4.28	Yes	No	0	8	5
23	R:R:F299	R:R:L308	26.027	2.44	Yes	No	0	5	5
24	R:R:E57	R:R:F299	20.5037	9.33	No	Yes	0	8	5
25	R:R:E57	R:R:P294	19.39	3.14	No	No	0	8	9
26	R:R:D86	R:R:P294	10.2781	3.22	Yes	No	11	9	9
27	R:R:G51	R:R:V94	10.2646	1.84	No	No	0	5	6
28	R:R:L127	R:R:Y297	12.8371	10.55	Yes	Yes	1	8	9
29	R:R:F202	R:R:W260	32.2512	3.01	Yes	Yes	1	8	8
30	R:R:F202	R:R:F203	95.763	6.43	Yes	Yes	1	8	4
31	R:R:F203	S:S:I200	97.3659	18.84	Yes	No	1	4	4
32	R:R:L268	S:S:I200	55.1368	2.85	Yes	No	1	5	4
33	R:R:L268	R:R:V196	12.8912	4.47	Yes	Yes	1	5	3
34	R:R:V196	S:S:L269	26.0525	2.98	Yes	No	0	3	4
35	R:R:N193	S:S:L269	24.9178	2.75	No	No	0	3	4
36	R:R:N193	R:R:W175	23.0702	9.04	No	No	4	3	4
37	R:R:H194	R:R:W175	22.6425	5.29	Yes	No	4	7	4
38	R:R:T131	R:R:Y213	10.5483	9.99	No	Yes	0	8	9
39	R:R:L212	R:R:Y135	21.5078	5.86	Yes	Yes	0	6	8
40	R:R:Y135	R:R:Y139	34.3449	5.96	Yes	No	0	8	6
41	R:R:Q215	R:R:Y135	29.8543	6.76	Yes	Yes	0	6	8
42	R:R:I216	R:R:Y135	11.3558	3.63	No	Yes	0	9	8
43	S:S:Q211	S:S:Q215	25.7928	12.8	Yes	Yes	0	2	6
44	R:R:N140	R:R:Y139	22.4984	3.49	No	No	0	5	6
45	R:R:Y139	S:S:I219	12.2578	4.84	No	No	0	6	6
46	R:R:N140	S:S:R222	19.9409	12.05	No	No	0	5	5
47	R:R:L268	S:S:L268	42.4633	5.54	Yes	Yes	1	5	5
48	S:S:I200	S:S:V196	42.5533	3.07	No	Yes	1	4	3
49	S:S:L268	S:S:V196	42.6164	2.98	Yes	Yes	1	5	3
50	R:R:I200	S:S:L268	99.2661	2.85	No	Yes	0	4	5
51	R:R:I200	S:S:F203	98.8083	16.33	No	Yes	0	4	4
52	R:R:Q211	S:S:Q211	37.4518	5.12	Yes	Yes	0	2	2
53	R:R:Q211	S:S:L212	49.6525	9.32	Yes	No	0	2	6
54	R:R:Q215	S:S:Y135	16.0415	13.53	Yes	Yes	7	6	8
55	S:S:F202	S:S:F203	92.8017	4.29	Yes	Yes	2	8	4
56	S:S:F202	S:S:W260	56.6587	4.01	Yes	Yes	2	8	8
57	S:S:F263	S:S:W260	100	7.02	Yes	Yes	0	6	8
58	S:S:C267	S:S:F263	80.8861	8.38	No	Yes	0	6	6
59	S:S:C267	S:S:L195	79.5969	3.17	No	No	0	6	5
60	S:S:L195	S:S:V187	78.3151	4.47	No	No	0	5	5
61	S:S:P189	S:S:V187	51.9234	1.77	No	No	0	3	5
62	S:S:P189	S:S:V113	39.3069	8.84	No	No	0	3	4
63	S:S:H96	S:S:V113	37.89	2.77	Yes	No	0	5	4
64	S:S:H96	S:S:V100	19.1979	4.15	Yes	No	0	5	4
65	S:S:D44	S:S:V100	17.7391	2.92	No	No	0	4	4
66	S:S:D44	S:S:F97	10.3577	11.94	No	Yes	8	4	5
67	S:S:F202	S:S:F256	21.7449	5.36	Yes	Yes	2	8	9
68	S:S:F256	S:S:M209	53.807	4.98	Yes	Yes	2	9	8
69	S:S:L127	S:S:M209	53.1211	2.83	Yes	Yes	0	8	8
70	S:S:L127	S:S:Y297	79.2366	3.52	Yes	Yes	0	8	9
71	S:S:I296	S:S:Y297	49.4965	4.84	No	Yes	3	8	9
72	S:S:I295	S:S:I296	48.9261	2.94	No	No	3	5	8
73	S:S:I295	S:S:M291	11.5434	2.92	No	Yes	3	5	5
74	S:S:N289	S:S:W260	28.6896	4.52	No	Yes	0	9	8
75	S:S:E57	S:S:I295	36.4957	9.56	No	No	3	8	5
76	S:S:E57	S:S:P294	35.6957	11	No	Yes	3	8	9
77	S:S:H96	S:S:L112	16.2772	6.43	Yes	No	0	5	5
78	S:S:G92	S:S:L112	11.8736	1.71	No	No	0	4	5
79	S:S:G92	S:S:L91	10.3997	1.71	No	No	0	4	4
80	S:S:A298	S:S:P294	33.7191	1.87	No	Yes	0	7	9
81	S:S:A298	S:S:V61	32.775	5.09	No	No	0	7	9
82	S:S:F299	S:S:V61	26.0825	2.62	No	No	0	5	9
83	S:S:F299	S:S:I64	17.3233	2.51	No	No	0	5	8
84	S:S:I64	S:S:V307	16.3282	1.54	No	No	0	8	8
85	S:S:F71	S:S:V307	14.329	2.62	Yes	No	0	8	8
86	S:S:L212	S:S:V132	65.2798	4.47	No	No	0	6	6
87	S:S:M156	S:S:V132	65.0322	3.04	No	No	0	5	6
88	S:S:A129	S:S:M156	64.9887	3.22	No	No	0	6	5
89	S:S:A129	S:S:L78	64.9812	3.15	No	No	0	6	8
90	S:S:I130	S:S:L78	65.0082	4.28	Yes	No	0	9	8
91	S:S:F202	S:S:I124	16.3747	5.02	Yes	Yes	2	8	8
92	S:S:G125	S:S:I124	24.8173	3.53	No	Yes	0	5	8
93	S:S:G125	S:S:V160	23.7456	3.68	No	No	0	5	6
94	S:S:V160	S:S:W161	22.6995	3.68	No	Yes	0	6	9
95	S:S:P189	S:S:Y188	11.8736	2.78	No	No	0	3	5
96	S:S:L178	S:S:Y188	10.3997	5.86	Yes	No	0	3	5
97	S:S:L190	S:S:V187	29.5571	4.47	Yes	No	0	3	5
98	S:S:L165	S:S:W161	10.6638	7.97	No	Yes	0	4	9
99	S:S:H194	S:S:L190	24.0068	12.86	Yes	Yes	16	7	3
100	S:S:N289	S:S:N293	27.0086	9.54	No	No	0	9	9
101	S:S:I219	S:S:L138	10.7674	4.28	No	No	0	6	8
102	S:S:H194	S:S:P171	17.5409	15.25	Yes	No	0	7	5
103	S:S:P171	S:S:W175	14.6472	5.4	No	No	0	5	4
104	S:S:N193	S:S:W175	11.7415	7.91	No	No	0	3	4
105	S:S:N193	S:S:S191	10.2841	7.45	No	No	0	3	6
106	S:S:F263	S:S:T282	18.9833	9.08	Yes	No	0	6	8
107	S:S:T282	S:S:Y266	16.0956	2.5	No	Yes	0	8	3
108	S:S:V186	S:S:Y266	11.7415	15.14	No	Yes	0	4	3
109	S:S:S274	S:S:V186	10.2841	3.23	Yes	No	0	3	4
110	R:R:G51	R:R:L93	12.1948	3.42	No	No	0	5	6
111	R:R:V196	S:S:L268	15.4112	2.98	Yes	Yes	1	3	5
112	S:S:I130	S:S:Y297	62.6983	6.04	Yes	Yes	3	9	9
113	R:R:F202	R:R:F256	63.5478	4.29	Yes	Yes	1	8	9
114	S:S:Q215	S:S:R218	25.6458	15.19	Yes	No	0	6	4
115	S:S:F256	S:S:W260	24.7332	7.02	Yes	Yes	2	9	8
116	S:S:L127	S:S:N293	26.8014	4.12	Yes	No	0	8	9
117	R:R:Q211	R:R:Q215	12.9632	2.56	Yes	Yes	0	2	6
118	S:S:L212	S:S:Y135	16.0475	5.86	No	Yes	0	6	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9LYC_nogp

PDB Summary
PDB	9LYC_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.5
Number of Linked Nodes	491
Number of Links	543
Number of Hubs	75
Number of Links mediated by Hubs	272
Number of Communities	17
Number of Nodes involved in Communities	102
Number of Links involved in Communities	134

Path Summary
Number Of Nodes in MetaPath	119
Number Of Links MetaPath	118
Number of Shortest Paths	173385
Length Of Smallest Path	3
Average Path Length	20.6387
Length of Longest Path	48
Minimum Path Strength	1.36
Average Path Strength	5.58723
Maximum Path Strength	14.35
Minimum Path Correlation	0.7
Average Path Correlation	0.963295
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.33333
Average % Of Corr. Nodes	49.7297
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.3959
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P46089
Sequence	>9LYC_nogp_Chain_R G P A A P L P S P K A W D V V L C I S G T L V S C E N A L V V A I I V G T P A F R A P M F L L V G S L A V A D L L A G L G L V L H F A A V F C I G S A E M S L V L V G V L A M A F T A S I G S L L A I T V D R Y L S L Y N A L T Y Y S E T T V T R T Y V M L A L V W G G A L G L G L L P V L A W N C L D G L T T C G V V Y P L S K N H L V V L A I A F F M V F G I M L Q L Y A Q I C R I V C R H A Q Q I A L Q R H A T R K G I A T L A V V L G A F A A C W L P F T V Y C L L G D A H S P P L Y T Y L T L L P A T Y N S M I N P I I Y A F R N Q D V Q K V L W A V C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	S
Protein	Receptor
UniProt	P46089
Sequence	>9LYC_nogp_Chain_S A P L P S P K A W D V V L C I S G T L V S C E N A L V V A I I V G T P A F R A P M F L L V G S L A V A D L L A G L G L V L H F A A V F C I G S A E M S L V L V G V L A M A F T A S I G S L L A I T V D R Y L S L Y N A L T Y Y S E T T V T R T Y V M L A L V W G G A L G L G L L P V L A W N C L D G L T T C G V V Y P L S K N H L V V L A I A F F M V F G I M L Q L Y A Q I C R I V C R H A Q Q I A L Q R H L H Y V A T R K G I A T L A V V L G A F A A C W L P F T V Y C L L G D A H S P P L Y T Y L T L L P A T Y N S M I N P I I Y A F R N Q D V Q K V L W A V C C C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8H8J	A	Orphan	Orphan	GPR35	Homo sapiens	Lodoxamide	Ca	chim(NtGi1L-G13)/β1/γ2	3.2	2023-02-08	doi.org/10.1038/s41421-022-00499-8
	8H8J (No Gprot)	A	Orphan	Orphan	GPR35	Homo sapiens	Lodoxamide	Ca		3.2	2023-02-08	doi.org/10.1038/s41421-022-00499-8
	8SAI	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (S12)	-	Gi1/β1/γ2	3.27	2023-10-04	doi.org/10.1073/pnas.2308435120
	8SAI (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (S12)	-		3.27	2023-10-04	doi.org/10.1073/pnas.2308435120
	8K4N	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 168719765	-	Gi1/β1/γ2	2.83	2023-10-25	To be published
	8K4N (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 168719765	-		2.83	2023-10-25	To be published
	8WRB	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (UBL)	-	Gi1/β1/γ2	2.91	2023-11-08	doi.org/10.1371/journal.pbio.3002387
	8WRB (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (UBL)	-		2.91	2023-11-08	doi.org/10.1371/journal.pbio.3002387
	8XBE	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-Lysophosphatidylserine	-	Gi1/β1/γ1	3.4	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	8XBE (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-Lysophosphatidylserine	-		3.4	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	8XBG	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-Lysophosphatidylserine	-	-	3.43	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	9M88	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	Oleic monoethanolamide	AF64394	-	3.1	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	9M8P	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	Oleic monoethanolamide	AF64394	-	3.42	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	9M8V	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	-	AF64394	chim(NtGi1-Gs)/β1/γ2	3.83	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	9M8V (No Gprot)	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	-	AF64394		3.83	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	8XBH	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 162656636	-	Gi1/β1/γ2	2.83	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8XBH (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 162656636	-		2.83	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8XBI	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 162656636	-	-	3.06	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8WW2	A	Orphan	Orphan	GPR3	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.79	2024-02-14	doi.org/10.1038/s41422-024-00932-5
	8WW2 (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	-	-		2.79	2024-02-14	doi.org/10.1038/s41422-024-00932-5
	8U8F	A	Orphan	Orphan	GPR3	Homo sapiens	Palmitic Acid	-	Gs/β1/γ2	3.49	2024-03-06	doi.org/10.1021/acs.biochem.3c00647
	8U8F (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	Palmitic Acid	-		3.49	2024-03-06	doi.org/10.1021/acs.biochem.3c00647
	8IYX	A	Orphan	Orphan	GPR34	Homo sapiens	YL-365	-	-	3.34	2024-03-20	doi.org/10.1073/pnas.2308435120
	8X2K	A	Orphan	Orphan	GPR3	Homo sapiens	Oleic monoethanolamide	-	chim(NtGi1-Gs)/β1/γ2	3.03	2024-04-03	doi.org/10.1038/s41422-023-00919-8
	8X2K (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	Oleic monoethanolamide	-		3.03	2024-04-03	doi.org/10.1038/s41422-023-00919-8
	8XOF	A	Orphan	Orphan	GPR30	Homo sapiens	Lys05	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.6	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOF (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	Lys05	-		2.6	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOG	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOG (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		2.9	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOH	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOH (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOI	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOI (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOJ	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOJ (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		3.1	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8IZ4	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (TJR)	-	Gi1/β1/γ2	2.94	2024-04-10	To be published
	8IZ4 (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (TJR)	-		2.94	2024-04-10	To be published
	9LYB	A	Orphan	Orphan	GPR3	Homo sapiens	-	-	Gs/β1/γ2	3.16	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYB (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	-	-		3.16	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYC	A	Orphan	Orphan	GPR3; GPR3	Homo sapiens	-	-	Gs/β1/γ2	3.06	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYC (No Gprot)	A	Orphan	Orphan	GPR3; GPR3	Homo sapiens	-	-		3.06	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYD	A	Orphan	Orphan	GPR3; GPR3	Homo sapiens	-	-	-	3.66	2025-04-09	doi.org/10.1016/j.celrep.2025.115478

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9LYC_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.