psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:T121	5.17	Yes	No	0	0	6
2	L:L:?1	R:R:I124	11.26	Yes	No	1	0	8
3	L:L:?1	R:R:G125	3	Yes	No	0	0	5
4	L:L:?1	R:R:V187	5.22	Yes	Yes	1	0	5
5	L:L:?1	R:R:L190	6.07	Yes	Yes	1	0	3
6	L:L:?1	R:R:L198	10.92	Yes	No	0	0	6
7	L:L:?1	R:R:F202	6.41	Yes	Yes	1	0	8
8	L:L:?1	R:R:V205	3.92	Yes	No	1	0	8
9	L:L:?1	R:R:F263	4.27	Yes	No	0	0	6
10	R:R:P40	R:R:S39	3.56	Yes	No	0	3	2
11	R:R:D44	R:R:P40	4.83	No	Yes	0	4	3
12	R:R:F97	R:R:P40	5.78	No	Yes	0	5	3
13	R:R:F101	R:R:P40	5.78	No	Yes	0	4	3
14	R:R:D44	R:R:K41	6.91	No	No	0	4	3
15	R:R:A42	R:R:W43	3.89	No	No	0	4	3
16	R:R:W43	R:R:Y280	3.86	No	Yes	0	3	4
17	R:R:L281	R:R:W43	4.56	No	No	0	4	3
18	R:R:D44	R:R:Y280	9.2	No	Yes	0	4	4
19	R:R:L284	R:R:V46	4.47	No	No	0	4	4
20	R:R:L47	R:R:Y280	3.52	No	Yes	0	4	4
21	R:R:L283	R:R:L47	4.15	No	No	0	4	4
22	R:R:C48	R:R:F97	13.97	No	No	0	3	5
23	R:R:G51	R:R:S50	3.71	No	No	0	5	5
24	R:R:S50	R:R:T287	7.99	No	No	0	5	6
25	R:R:G51	R:R:L93	3.42	No	No	0	5	6
26	R:R:T52	R:R:V94	3.17	No	No	0	4	6
27	R:R:N58	R:R:V54	4.43	Yes	Yes	0	9	7
28	R:R:G90	R:R:V54	3.68	No	Yes	0	7	7
29	R:R:S290	R:R:V54	3.23	No	Yes	0	9	7
30	R:R:M291	R:R:V54	4.56	Yes	Yes	0	5	7
31	R:R:L87	R:R:S55	3	No	No	0	7	6
32	R:R:E57	R:R:N58	5.26	No	Yes	1	8	9
33	R:R:E57	R:R:M291	4.06	No	Yes	0	8	5
34	R:R:E57	R:R:P294	9.43	No	No	1	8	9
35	R:R:D86	R:R:N58	13.46	Yes	Yes	1	9	9
36	R:R:N58	R:R:P294	11.4	Yes	No	1	9	9
37	R:R:A59	R:R:L87	4.73	No	No	0	5	7
38	R:R:L308	R:R:L60	4.15	No	No	0	5	7
39	R:R:A83	R:R:V61	3.39	No	No	0	9	9
40	R:R:P294	R:R:V61	3.53	No	No	0	9	9
41	R:R:A298	R:R:V61	3.39	No	No	0	7	9
42	R:R:A83	R:R:V62	3.39	No	No	0	9	7
43	R:R:V62	R:R:V84	4.81	No	No	0	7	6
44	R:R:I64	R:R:V307	3.07	No	No	0	8	8
45	R:R:F76	R:R:I65	6.28	No	No	0	9	7
46	R:R:P69	R:R:T68	6.99	No	No	0	5	7
47	R:R:F71	R:R:T68	5.19	Yes	No	0	8	7
48	R:R:F71	R:R:F76	11.79	Yes	No	0	8	9
49	R:R:D303	R:R:F71	8.36	No	Yes	0	7	8
50	R:R:P74	R:R:T153	6.99	No	Yes	0	5	6
51	R:R:D133	R:R:M75	5.54	No	No	0	9	8
52	R:R:M75	R:R:R134	7.44	No	No	0	8	9
53	R:R:F76	R:R:N301	6.04	No	No	0	9	8
54	R:R:L77	R:R:T153	4.42	No	Yes	0	4	6
55	R:R:L77	R:R:Y154	4.69	No	No	0	4	1
56	R:R:L78	R:R:T153	2.95	No	Yes	2	8	6
57	R:R:L157	R:R:L78	4.15	No	No	2	7	8
58	R:R:S126	R:R:S81	4.89	No	No	0	8	9
59	R:R:L157	R:R:S81	3	No	No	0	7	9
60	R:R:S81	R:R:W161	6.18	No	Yes	0	9	9
61	R:R:D86	R:R:L82	4.07	Yes	Yes	1	9	9
62	R:R:L82	R:R:S123	3	Yes	No	1	9	9
63	R:R:L82	R:R:S126	6.01	Yes	No	0	9	8
64	R:R:L127	R:R:L82	6.92	Yes	Yes	1	8	9
65	R:R:I130	R:R:L82	4.28	No	Yes	0	9	9
66	R:R:L82	R:R:N293	6.87	Yes	Yes	1	9	9
67	R:R:D86	R:R:S123	7.36	Yes	No	1	9	9
68	R:R:D86	R:R:S290	10.31	Yes	No	0	9	9
69	R:R:D86	R:R:N293	6.73	Yes	Yes	1	9	9
70	R:R:A89	R:R:F120	4.16	No	No	0	8	4
71	R:R:L91	R:R:L95	4.15	No	No	0	4	7
72	R:R:G92	R:R:L116	5.13	No	No	0	4	5
73	R:R:L116	R:R:L93	6.92	No	No	0	5	6
74	R:R:L93	R:R:T287	2.95	No	No	0	6	6
75	R:R:L112	R:R:L95	6.92	Yes	No	0	5	7
76	R:R:A98	R:R:I103	3.25	No	No	0	5	5
77	R:R:E107	R:R:S105	4.31	No	No	0	1	7
78	R:R:M108	R:R:S105	3.07	No	No	0	4	7
79	R:R:L110	R:R:S109	4.5	No	No	0	5	8
80	R:R:P189	R:R:V113	10.6	Yes	No	1	3	4
81	R:R:L190	R:R:V113	4.47	Yes	No	1	3	4
82	R:R:G114	R:R:P171	4.06	No	No	0	5	5
83	R:R:F120	R:R:W260	9.02	No	Yes	0	4	8
84	R:R:A164	R:R:T121	3.36	No	No	0	8	6
85	R:R:L167	R:R:T121	5.9	No	No	0	6	6
86	R:R:A122	R:R:W161	7.78	No	Yes	0	7	9
87	R:R:I124	R:R:V205	4.61	No	No	1	8	8
88	R:R:I124	R:R:W260	9.4	No	Yes	1	8	8
89	R:R:G125	R:R:V160	3.68	No	No	0	5	6
90	R:R:L127	R:R:N289	4.12	Yes	Yes	1	8	9
91	R:R:L127	R:R:N293	12.36	Yes	Yes	1	8	9
92	R:R:L127	R:R:Y297	4.69	Yes	Yes	1	8	9
93	R:R:L128	R:R:V205	5.96	No	No	0	7	8
94	R:R:I130	R:R:Y297	7.25	No	Yes	0	9	9
95	R:R:M209	R:R:T131	7.53	No	No	1	8	8
96	R:R:L212	R:R:T131	5.9	No	No	0	6	8
97	R:R:T131	R:R:Y213	11.24	No	Yes	1	8	9
98	R:R:L136	R:R:V132	2.98	No	No	0	5	6
99	R:R:R134	R:R:Y213	6.17	No	Yes	1	9	9
100	R:R:R134	R:R:Y297	8.23	No	Yes	1	9	9
101	R:R:Y135	R:R:Y139	5.96	No	No	0	8	6
102	R:R:L212	R:R:Y135	5.86	No	No	0	6	8
103	R:R:Q215	R:R:Y135	15.78	No	No	0	6	8
104	R:R:S137	R:R:Y144	8.9	No	No	0	8	8
105	R:R:I216	R:R:L138	4.28	No	No	0	9	8
106	R:R:N140	R:R:Y139	6.98	No	No	0	5	6
107	R:R:N140	R:R:T143	4.39	No	No	0	5	5
108	R:R:S146	R:R:T148	6.4	No	No	0	4	6
109	R:R:E147	R:R:V150	8.56	No	No	0	5	3
110	R:R:V150	R:R:Y154	6.31	No	No	0	3	1
111	R:R:L157	R:R:T153	2.95	No	Yes	2	7	6
112	R:R:G166	R:R:L165	3.42	No	No	0	2	4
113	R:R:L167	R:R:L198	5.54	No	No	0	6	6
114	R:R:H194	R:R:L170	15.43	Yes	No	0	7	4
115	R:R:H194	R:R:P171	6.1	Yes	No	0	7	5
116	R:R:C177	R:R:N176	3.15	No	No	0	5	5
117	R:R:N176	R:R:S191	4.47	No	No	0	5	6
118	R:R:C177	R:R:C184	7.28	No	No	0	5	9
119	R:R:D179	R:R:L181	5.43	No	No	0	1	2
120	R:R:S191	R:R:T182	3.2	No	No	0	6	4
121	R:R:K192	R:R:T183	3	No	No	0	4	3
122	R:R:K192	R:R:V186	3.04	No	No	0	4	4
123	R:R:L195	R:R:V186	4.47	No	No	0	5	4
124	R:R:P189	R:R:V187	3.53	Yes	Yes	1	3	5
125	R:R:L190	R:R:V187	2.98	Yes	Yes	1	3	5
126	R:R:L195	R:R:V187	2.98	No	Yes	0	5	5
127	R:R:P189	R:R:Y188	4.17	Yes	No	0	3	5
128	R:R:L190	R:R:P189	4.93	Yes	Yes	1	3	3
129	R:R:H194	R:R:L198	12.86	Yes	No	0	7	6
130	R:R:C267	R:R:L195	7.94	No	No	0	6	5
131	R:R:F202	R:R:F203	5.36	Yes	No	1	8	4
132	R:R:F202	R:R:F256	6.43	Yes	Yes	1	8	9
133	R:R:F202	R:R:W260	9.02	Yes	Yes	1	8	8
134	R:R:F202	R:R:T264	15.56	Yes	No	1	8	5
135	R:R:F203	R:R:T264	7.78	No	No	1	4	5
136	R:R:F206	R:R:L210	13.4	No	No	0	6	4
137	R:R:F206	R:R:F256	5.36	No	Yes	0	6	9
138	R:R:A257	R:R:F206	4.16	No	No	0	5	6
139	R:R:M209	R:R:Y213	3.59	No	Yes	1	8	9
140	R:R:L253	R:R:M209	4.24	No	No	1	7	8
141	R:R:L210	R:R:L253	4.15	No	No	0	4	7
142	R:R:Q211	R:R:Q215	3.84	No	No	0	2	6
143	R:R:V252	R:R:Y213	6.31	No	Yes	0	7	9
144	R:R:L253	R:R:Y213	8.21	No	Yes	1	7	9
145	R:R:Y213	R:R:Y297	4.96	Yes	Yes	1	9	9
146	R:R:C217	R:R:L249	3.17	No	No	0	6	7
147	R:R:C221	R:R:R243	4.18	No	Yes	0	6	5
148	R:R:H223	R:R:R222	7.9	No	No	0	7	5
149	R:R:A224	R:R:R243	4.15	No	Yes	0	5	5
150	R:R:Q225	R:R:Q226	11.52	No	No	3	6	5
151	R:R:K244	R:R:T248	6.01	No	No	0	8	8
152	R:R:I296	R:R:V251	3.07	No	No	0	8	6
153	R:R:F256	R:R:W260	6.01	Yes	Yes	1	9	8
154	R:R:F256	R:R:N289	7.25	Yes	Yes	1	9	9
155	R:R:C259	R:R:N289	3.15	No	Yes	0	8	9
156	R:R:A286	R:R:W260	5.19	No	Yes	0	6	8
157	R:R:N289	R:R:W260	13.56	Yes	Yes	1	9	8
158	R:R:P262	R:R:T282	3.5	No	No	0	9	8
159	R:R:P262	R:R:P285	3.9	No	No	0	9	7
160	R:R:C267	R:R:F263	8.38	No	No	0	6	6
161	R:R:S274	R:R:Y266	6.36	No	Yes	0	3	3
162	R:R:Y266	R:R:Y278	7.94	Yes	No	0	3	3
163	R:R:T279	R:R:Y266	4.99	No	Yes	0	4	3
164	R:R:T282	R:R:Y266	7.49	No	Yes	0	8	3
165	R:R:L277	R:R:P275	3.28	No	No	4	4	3
166	R:R:P275	R:R:Y278	8.34	No	No	4	3	3
167	R:R:L277	R:R:Y278	9.38	No	No	4	4	3
168	R:R:T279	R:R:Y280	6.24	No	Yes	0	4	4
169	R:R:L283	R:R:T287	2.95	No	No	0	4	6
170	R:R:L284	R:R:P285	4.93	No	No	0	4	7
171	R:R:L284	R:R:Y288	7.03	No	No	0	4	4
172	R:R:M291	R:R:Y288	5.99	Yes	No	0	5	4
173	R:R:N289	R:R:N293	12.26	Yes	Yes	1	9	9
174	R:R:I296	R:R:Y297	9.67	No	Yes	0	8	9
175	R:R:N301	R:R:V304	8.87	No	No	0	8	8
176	R:R:Q302	R:R:Q305	3.84	No	No	0	5	8
177	R:R:L308	R:R:V304	2.98	No	No	0	5	8
178	R:R:C313	R:R:W309	3.92	No	No	0	4	4
179	R:R:G270	R:R:Y266	2.9	No	Yes	0	3	3
180	R:R:I64	R:R:L60	2.85	No	No	0	8	7
181	R:R:I208	R:R:L128	2.85	No	No	0	5	7
182	R:R:I219	R:R:L138	2.85	No	No	0	6	8
183	R:R:I208	R:R:L212	2.85	No	No	0	5	6
184	R:R:L53	R:R:M291	2.83	No	Yes	0	4	5
185	R:R:L112	R:R:M108	2.83	Yes	No	0	5	4
186	R:R:H96	R:R:V100	2.77	No	No	0	5	4
187	R:R:H96	R:R:V113	2.77	No	No	0	5	4
188	R:R:L110	R:R:L178	2.77	No	No	0	5	3
189	L:L:?1	R:R:A201	2.76	Yes	No	0	0	4
190	R:R:H223	R:R:I219	2.65	No	No	0	7	6
191	R:R:A85	R:R:W161	2.59	No	Yes	0	8	9
192	R:R:H96	R:R:L112	2.57	No	Yes	0	5	5
193	R:R:H194	R:R:N176	2.55	Yes	No	0	7	5
194	R:R:I246	R:R:R243	2.51	No	Yes	0	7	5
195	R:R:F202	R:R:L261	2.44	Yes	No	1	8	4
196	R:R:F203	R:R:L261	2.44	No	No	1	4	4
197	R:R:L77	R:R:R72	2.43	No	No	0	4	8
198	R:R:T182	R:R:W175	2.43	No	No	0	4	4
199	R:R:I216	R:R:Y213	2.42	No	Yes	0	9	9
200	R:R:L249	R:R:Y213	2.34	No	Yes	0	7	9
201	R:R:M118	R:R:W161	2.33	No	Yes	0	4	9
202	R:R:D133	R:R:Y144	2.3	No	No	0	9	8
203	R:R:L88	R:R:W161	2.28	No	Yes	0	7	9
204	R:R:G162	R:R:G163	2.11	No	No	0	3	3
205	R:R:G168	R:R:P171	2.03	No	No	0	6	5
206	R:R:Y144	R:R:Y145	1.99	No	No	0	8	4
207	R:R:C184	R:R:G185	1.96	No	No	0	9	5
208	R:R:A83	R:R:G80	1.95	No	No	0	9	6
209	R:R:A117	R:R:G168	1.95	No	No	0	4	6
210	R:R:A272	R:R:G185	1.95	No	No	0	3	5
211	R:R:P275	R:R:P276	1.95	No	No	0	3	2
212	R:R:A73	R:R:P74	1.87	No	No	0	7	5
213	R:R:G90	R:R:S55	1.86	No	No	0	7	6
214	R:R:G51	R:R:V94	1.84	No	No	0	5	6
215	R:R:G80	R:R:V66	1.84	No	No	0	6	4
216	R:R:G92	R:R:V115	1.84	No	No	0	4	4
217	R:R:C217	R:R:C221	1.82	No	No	0	6	6
218	R:R:A199	R:R:C267	1.81	No	No	0	4	6
219	R:R:A119	R:R:A89	1.79	No	No	0	6	8
220	R:R:G80	R:R:I65	1.76	No	No	0	6	7
221	R:R:P74	R:R:T149	1.75	No	No	0	5	8
222	R:R:G162	R:R:L165	1.71	No	No	0	3	4
223	R:R:G166	R:R:L169	1.71	No	No	0	2	3
224	R:R:G207	R:R:L210	1.71	No	No	0	4	4
225	R:R:A298	R:R:V79	1.7	No	No	0	7	7
226	R:R:A129	R:R:V160	1.7	No	No	0	6	6
227	R:R:D179	R:R:G180	1.68	No	No	0	1	3
228	R:R:L110	R:R:P189	1.64	No	Yes	0	5	3
229	R:R:C259	R:R:I292	1.64	No	No	0	8	5
230	R:R:A255	R:R:I292	1.62	No	No	0	6	5
231	R:R:A129	R:R:M156	1.61	No	No	0	6	5
232	R:R:V45	R:R:V46	1.6	No	No	0	5	4
233	R:R:T151	R:R:V150	1.59	No	No	0	4	3
234	R:R:T248	R:R:V252	1.59	No	No	0	8	7
235	R:R:A99	R:R:L112	1.58	No	Yes	0	4	5
236	R:R:A174	R:R:L169	1.58	No	No	0	4	3
237	R:R:A174	R:R:L170	1.58	No	No	0	4	4
238	R:R:A199	R:R:L268	1.58	No	No	0	4	5
239	R:R:T148	R:R:T149	1.57	No	No	0	6	8
240	R:R:I103	R:R:S105	1.55	No	No	0	5	7
241	R:R:I49	R:R:V46	1.54	No	No	0	4	4
242	R:R:I64	R:R:V311	1.54	No	No	0	8	5
243	R:R:I200	R:R:V196	1.54	No	No	0	4	3
244	R:R:I216	R:R:V220	1.54	No	No	0	9	8
245	R:R:A272	R:R:D271	1.54	No	No	0	3	4
246	R:R:M156	R:R:V132	1.52	No	No	0	5	6
247	R:R:K192	R:R:V196	1.52	No	No	0	4	3
248	R:R:K306	R:R:V307	1.52	No	No	0	5	8
249	R:R:G245	R:R:R243	1.5	No	Yes	0	8	5
250	R:R:L167	R:R:V197	1.49	No	No	0	6	5
251	R:R:N193	R:R:S191	1.49	No	No	0	3	6
252	R:R:L261	R:R:V265	1.49	No	No	0	4	6
253	R:R:L269	R:R:V265	1.49	No	No	0	4	6
254	R:R:A228	R:R:H232	1.46	No	No	0	4	3
255	R:R:A70	R:R:F71	1.39	No	Yes	0	6	8
256	R:R:L173	R:R:L178	1.38	No	No	0	4	3
257	R:R:H223	R:R:I227	1.33	No	No	0	7	7
258	R:R:L229	R:R:Q225	1.33	No	No	3	3	6
259	R:R:L229	R:R:Q226	1.33	No	No	3	3	5
260	R:R:R152	R:R:T151	1.29	No	No	0	7	4
261	R:R:F299	R:R:I295	1.26	No	No	0	5	5
262	R:R:H232	R:R:R231	1.13	No	No	0	3	4
263	R:R:F299	R:R:R300	1.07	No	No	0	5	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	5.9	10	1	0
2	R:R:P40	4.9875	4	0	3
3	R:R:V54	3.975	4	0	7
4	R:R:N58	8.6375	4	1	9
5	R:R:F71	6.6825	4	0	8
6	R:R:L82	5.19167	6	1	9
7	R:R:D86	8.386	5	1	9
8	R:R:L112	3.475	4	0	5
9	R:R:L127	7.0225	4	1	8
10	R:R:T153	4.3275	4	2	6
11	R:R:W161	4.232	5	0	9
12	R:R:V187	3.6775	4	1	5
13	R:R:P189	4.974	5	1	3
14	R:R:L190	4.6125	4	1	3
15	R:R:H194	9.235	4	0	7
16	R:R:F202	7.53667	6	1	8
17	R:R:Y213	5.655	8	1	9
18	R:R:R243	3.085	4	0	5
19	R:R:F256	6.2625	4	1	9
20	R:R:W260	8.7	6	1	8
21	R:R:Y266	5.936	5	0	3
22	R:R:Y280	5.705	4	0	4
23	R:R:N289	8.068	5	1	9
24	R:R:M291	4.36	4	0	5
25	R:R:N293	9.555	4	1	9
26	R:R:Y297	6.96	5	1	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:I124	38.0071	11.26	Yes	No	1	0	8
2	R:R:I124	R:R:W260	39.819	9.4	No	Yes	1	8	8
3	R:R:N289	R:R:W260	81.7102	13.56	Yes	Yes	1	9	8
4	R:R:N289	R:R:N293	97.5638	12.26	Yes	Yes	1	9	9
5	R:R:D86	R:R:N293	97.879	6.73	Yes	Yes	1	9	9
6	R:R:D86	R:R:N58	92.5694	13.46	Yes	Yes	1	9	9
7	R:R:N58	R:R:V54	38.3508	4.43	Yes	Yes	0	9	7
8	R:R:M291	R:R:V54	68.547	4.56	Yes	Yes	0	5	7
9	R:R:M291	R:R:Y288	100	5.99	Yes	No	0	5	4
10	R:R:L284	R:R:Y288	97.6187	7.03	No	No	0	4	4
11	R:R:L284	R:R:P285	88.2705	4.93	No	No	0	4	7
12	R:R:P262	R:R:P285	85.8688	3.9	No	No	0	9	7
13	R:R:P262	R:R:T282	83.4631	3.5	No	No	0	9	8
14	R:R:T282	R:R:Y266	81.0534	7.49	No	Yes	0	8	3
15	R:R:T279	R:R:Y266	64.0712	4.99	No	Yes	0	4	3
16	R:R:T279	R:R:Y280	61.6289	6.24	No	Yes	0	4	4
17	R:R:D44	R:R:Y280	17.5272	9.2	No	Yes	0	4	4
18	R:R:D44	R:R:P40	12.6772	4.83	No	Yes	0	4	3
19	L:L:?1	R:R:F202	79.8211	6.41	Yes	Yes	1	0	8
20	R:R:F202	R:R:W260	41.0452	9.02	Yes	Yes	1	8	8
21	R:R:F202	R:R:F256	44.3132	6.43	Yes	Yes	1	8	9
22	R:R:F256	R:R:N289	42.6111	7.25	Yes	Yes	1	9	9
23	R:R:D86	R:R:S290	38.7961	10.31	Yes	No	0	9	9
24	R:R:S290	R:R:V54	38.0986	3.23	No	Yes	0	9	7
25	R:R:E57	R:R:N58	34.8612	5.26	No	Yes	1	8	9
26	R:R:E57	R:R:M291	36.2257	4.06	No	Yes	0	8	5
27	R:R:L47	R:R:Y280	34.8673	3.52	No	Yes	0	4	4
28	R:R:L283	R:R:L47	32.5674	4.15	No	No	0	4	4
29	R:R:L283	R:R:T287	30.0742	2.95	No	No	0	4	6
30	R:R:S50	R:R:T287	10.1007	7.99	No	No	0	5	6
31	R:R:L93	R:R:T287	17.4865	2.95	No	No	0	6	6
32	R:R:G51	R:R:V94	10.1169	1.84	No	No	0	5	6
33	R:R:N58	R:R:P294	19.4021	11.4	Yes	No	1	9	9
34	R:R:P294	R:R:V61	20.6731	3.53	No	No	0	9	9
35	R:R:A83	R:R:V61	18.0803	3.39	No	No	0	9	9
36	R:R:A83	R:R:G80	15.4509	1.95	No	No	0	9	6
37	R:R:G80	R:R:I65	13.6777	1.76	No	No	0	6	7
38	R:R:F76	R:R:I65	12.785	6.28	No	No	0	9	7
39	R:R:L127	R:R:N289	26.8551	4.12	Yes	Yes	1	8	9
40	R:R:L127	R:R:L82	27.6848	6.92	Yes	Yes	1	8	9
41	R:R:L82	R:R:S126	33.4621	6.01	Yes	No	0	9	8
42	R:R:S126	R:R:S81	31.9837	4.89	No	No	0	8	9
43	R:R:L157	R:R:S81	23.028	3	No	No	0	7	9
44	R:R:L157	R:R:T153	19.9837	2.95	No	Yes	2	7	6
45	R:R:L82	R:R:N293	12.6507	6.87	Yes	Yes	1	9	9
46	R:R:L127	R:R:Y297	41.3462	4.69	Yes	Yes	1	8	9
47	R:R:L77	R:R:T153	10.8592	4.42	No	Yes	0	4	6
48	R:R:I130	R:R:L82	16.1139	4.28	No	Yes	0	9	9
49	R:R:I130	R:R:Y297	15.3127	7.25	No	Yes	0	9	9
50	L:L:?1	R:R:L190	33.1978	6.07	Yes	Yes	1	0	3
51	R:R:L190	R:R:V113	21.275	4.47	Yes	No	1	3	4
52	R:R:H96	R:R:V113	20.0081	2.77	No	No	0	5	4
53	R:R:H96	R:R:L112	16.4514	2.57	No	Yes	0	5	5
54	L:L:?1	R:R:V187	22.7311	5.22	Yes	Yes	1	0	5
55	R:R:P189	R:R:V187	10.9161	3.53	Yes	Yes	1	3	5
56	R:R:L110	R:R:P189	14.2715	1.64	No	Yes	0	5	3
57	R:R:L190	R:R:P189	10.5704	4.93	Yes	Yes	1	3	3
58	L:L:?1	R:R:L198	44.1322	10.92	Yes	No	0	0	6
59	R:R:H194	R:R:L198	39.1764	12.86	Yes	No	0	7	6
60	L:L:?1	R:R:G125	10.9181	3	Yes	No	0	0	5
61	R:R:L212	R:R:T131	12.7951	5.9	No	No	0	6	8
62	R:R:Y213	R:R:Y297	41.5475	4.96	Yes	Yes	1	9	9
63	R:R:T131	R:R:Y213	13.5841	11.24	No	Yes	1	8	9
64	R:R:I216	R:R:Y213	13.8241	2.42	No	Yes	0	9	9
65	R:R:H194	R:R:L170	12.7239	15.43	Yes	No	0	7	4
66	R:R:A174	R:R:L170	10.9181	1.58	No	No	0	4	4
67	R:R:H194	R:R:N176	18.1169	2.55	Yes	No	0	7	5
68	R:R:L195	R:R:V187	11.0585	2.98	No	Yes	0	5	5
69	R:R:L249	R:R:Y213	14.0051	2.34	No	Yes	0	7	9
70	R:R:C217	R:R:L249	12.0142	3.17	No	No	0	6	7
71	R:R:C217	R:R:C221	10.0214	1.82	No	No	0	6	6
72	R:R:Y266	R:R:Y278	10.1495	7.94	Yes	No	0	3	3
73	R:R:D86	R:R:L82	34.0051	4.07	Yes	Yes	1	9	9
74	R:R:L127	R:R:N293	13.1591	12.36	Yes	Yes	1	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:T121	5.17	1	Yes	No	0	6	0	1
L:L:?1	R:R:I124	11.26	1	Yes	No	0	8	0	1
L:L:?1	R:R:G125	3	1	Yes	No	0	5	0	1
L:L:?1	R:R:V187	5.22	1	Yes	Yes	0	5	0	1
L:L:?1	R:R:L190	6.07	1	Yes	Yes	0	3	0	1
L:L:?1	R:R:L198	10.92	1	Yes	No	0	6	0	1
L:L:?1	R:R:F202	6.41	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:V205	3.92	1	Yes	No	0	8	0	1
L:L:?1	R:R:F263	4.27	1	Yes	No	0	6	0	1
R:R:P189	R:R:V113	10.6	1	Yes	No	3	4	2	2
R:R:L190	R:R:V113	4.47	1	Yes	No	3	4	1	2
R:R:A164	R:R:T121	3.36	0	No	No	8	6	2	1
R:R:L167	R:R:T121	5.9	0	No	No	6	6	2	1
R:R:I124	R:R:V205	4.61	1	No	No	8	8	1	1
R:R:I124	R:R:W260	9.4	1	No	Yes	8	8	1	2
R:R:G125	R:R:V160	3.68	0	No	No	5	6	1	2
R:R:L128	R:R:V205	5.96	0	No	No	7	8	2	1
R:R:L167	R:R:L198	5.54	0	No	No	6	6	2	1
R:R:P189	R:R:V187	3.53	1	Yes	Yes	3	5	2	1
R:R:L190	R:R:V187	2.98	1	Yes	Yes	3	5	1	1
R:R:L195	R:R:V187	2.98	0	No	Yes	5	5	2	1
R:R:L190	R:R:P189	4.93	1	Yes	Yes	3	3	1	2
R:R:H194	R:R:L198	12.86	0	Yes	No	7	6	2	1
R:R:C267	R:R:L195	7.94	0	No	No	6	5	2	2
R:R:F202	R:R:F203	5.36	1	Yes	No	8	4	1	2
R:R:F202	R:R:F256	6.43	1	Yes	Yes	8	9	1	2
R:R:F202	R:R:W260	9.02	1	Yes	Yes	8	8	1	2
R:R:F202	R:R:T264	15.56	1	Yes	No	8	5	1	2
R:R:F203	R:R:T264	7.78	1	No	No	4	5	2	2
R:R:F256	R:R:W260	6.01	1	Yes	Yes	9	8	2	2
R:R:C267	R:R:F263	8.38	0	No	No	6	6	2	1
L:L:?1	R:R:A201	2.76	1	Yes	No	0	4	0	1
R:R:F202	R:R:L261	2.44	1	Yes	No	8	4	1	2
R:R:F203	R:R:L261	2.44	1	No	No	4	4	2	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8U8F_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.95
Number of Linked Nodes	242
Number of Links	263
Number of Hubs	26
Number of Links mediated by Hubs	103
Number of Communities	4
Number of Nodes involved in Communities	37
Number of Links involved in Communities	53

Path Summary
Number Of Nodes in MetaPath	75
Number Of Links MetaPath	74
Number of Shortest Paths	100028
Length Of Smallest Path	3
Average Path Length	16.7142
Length of Longest Path	33
Minimum Path Strength	1.165
Average Path Strength	6.1622
Maximum Path Strength	14.145
Minimum Path Correlation	0.7
Average Path Correlation	0.930127
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.84615
Average % Of Corr. Nodes	45.804
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.4125
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development
Gene Ontology	Biological Process	• multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • bioactive lipid receptor activity • sphingosine-1-phosphate receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • multicellular organismal process • homeostatic process • positive regulation of biological process • adaptive thermogenesis • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • regulation of multicellular organismal process • regulation of cellular component organization • sexual reproduction • regulation of reproductive process • reproductive process • meiotic cell cycle process • cellular component organization • meiotic nuclear division • cell cycle • cellular component organization or biogenesis • regulation of cell cycle • cell cycle process • regulation of meiotic cell cycle • regulation of cell cycle process • meiotic cell cycle • organelle fission • regulation of organelle organization • regulation of meiotic nuclear division • organelle organization • nuclear division • regulation of nuclear division • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • developmental process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • cellular homeostasis • chemical homeostasis • glucose homeostasis • carbohydrate homeostasis • intracellular chemical homeostasis • intracellular glucose homeostasis • system process • nervous system process • neuromuscular process • regulation of system process • skeletal muscle contraction • muscle contraction • muscle system process • regulation of muscle system process • striated muscle contraction • multicellular organismal movement • musculoskeletal movement • regulation of striated muscle contraction • regulation of muscle contraction • regulation of skeletal muscle contraction • sensory perception of chemical stimulus • sensory perception • sensory perception of smell • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • multicellular organism development • skeletal system development • bone development • system development • response to pH • cellular response to pH • response to abiotic stimulus • cellular response to acidic pH • response to acidic pH • cellular response to abiotic stimulus • cellular response to environmental stimulus • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • positive regulation of cell communication • regulation of localization • establishment of protein localization • nitrogen compound transport • positive regulation of establishment of protein localization • localization • establishment of localization in cell • positive regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of insulin secretion • intracellular protein localization • regulation of peptide hormone secretion • regulation of hormone levels • positive regulation of peptide hormone secretion • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular response to carbohydrate stimulus • response to glucose • positive regulation of protein localization • insulin secretion involved in cellular response to glucose stimulus • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • positive regulation of secretion by cell • hormone secretion • protein localization to extracellular region • positive regulation of protein transport • peptide secretion • regulation of secretion by cell • secretion by cell • positive regulation of hormone secretion • response to monosaccharide • response to carbohydrate • positive regulation of secretion • signal release • cellular response to hexose stimulus • cellular response to monosaccharide stimulus • positive regulation of cellular process • positive regulation of peptide secretion • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • cellular response to glucose stimulus • regulation of protein transport • positive regulation of protein secretion • peptide transport • response to hexose • positive regulation of transport • regulation of cellular localization • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • regulation of insulin secretion involved in cellular response to glucose stimulus • hormone transport • regulation of cell communication • insulin secretion • positive regulation of signaling • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • serotonin receptor signaling pathway • adenylate cyclase-activating serotonin receptor signaling pathway • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • cell surface receptor signaling pathway • bile acid signaling pathway • adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway • renal system process • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	PLM
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	PLM
Name	Palmitic Acid
Synonyms	Hexaectylic acid
Identifier
Formula	C16 H32 O2
Molecular Weight	256.424
SMILES
PubChem	985
Formal Charge	0
Total Atoms	50
Total Chiral Atoms	0
Total Bonds	49
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P46089
Sequence	>8U8F_nogp_Chain_R S P K A W D V V L C I S G T L V S C E N A L V V A I I V G T P A F R A P M F L L V G S L A V A D L L A G L G L V L H F A A V F C I G S A E M S L V L V G V L A M A F T A S I G S L L A I T V D R Y L S L Y N A L T Y Y S E T T V T R T Y V M L A L V W G G A L G L G L L P V L A W N C L D G L T T C G V V Y P L S K N H L V V L A I A F F M V F G I M L Q L Y A Q I C R I V C R H A Q Q I A L Q R H R K G I A T L A V V L G A F A A C W L P F T V Y C L L G D A H S P P L Y T Y L T L L P A T Y N S M I N P I I Y A F R N Q D V Q K V L W A V C C Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8H8J	A	Orphan	Orphan	GPR35	Homo sapiens	Lodoxamide	Ca	chim(NtGi1L-G13)/β1/γ2	3.2	2023-02-08	doi.org/10.1038/s41421-022-00499-8
	8H8J (No Gprot)	A	Orphan	Orphan	GPR35	Homo sapiens	Lodoxamide	Ca		3.2	2023-02-08	doi.org/10.1038/s41421-022-00499-8
	8SAI	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (S12)	-	Gi1/β1/γ2	3.27	2023-10-04	doi.org/10.1073/pnas.2308435120
	8SAI (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (S12)	-		3.27	2023-10-04	doi.org/10.1073/pnas.2308435120
	8K4N	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 168719765	-	Gi1/β1/γ2	2.83	2023-10-25	To be published
	8K4N (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 168719765	-		2.83	2023-10-25	To be published
	8WRB	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (UBL)	-	Gi1/β1/γ2	2.91	2023-11-08	doi.org/10.1371/journal.pbio.3002387
	8WRB (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (UBL)	-		2.91	2023-11-08	doi.org/10.1371/journal.pbio.3002387
	8XBE	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-Lysophosphatidylserine	-	Gi1/β1/γ1	3.4	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	8XBE (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-Lysophosphatidylserine	-		3.4	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	8XBG	A	Orphan	Orphan	GPR34	Homo sapiens	S3E-Lysophosphatidylserine	-	-	3.43	2024-05-15	doi.org/10.1038/s41467-024-45046-z
	9M88	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	Oleic monoethanolamide	AF64394	-	3.1	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	9M8P	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	Oleic monoethanolamide	AF64394	-	3.42	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	9M8V	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	-	AF64394	chim(NtGi1-Gs)/β1/γ2	3.83	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	9M8V (No Gprot)	A	Orphan	Orphan	GPR3 ; GPR3	Homo sapiens	-	AF64394		3.83	2025-09-24	doi.org/10.1038/s41467-025-63422-1
	8XBH	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 162656636	-	Gi1/β1/γ2	2.83	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8XBH (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 162656636	-		2.83	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8XBI	A	Orphan	Orphan	GPR34	Homo sapiens	PubChem 162656636	-	-	3.06	2023-12-27	doi.org/10.1038/s41467-024-45046-z
	8WW2	A	Orphan	Orphan	GPR3	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.79	2024-02-14	doi.org/10.1038/s41422-024-00932-5
	8WW2 (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	-	-		2.79	2024-02-14	doi.org/10.1038/s41422-024-00932-5
	8U8F	A	Orphan	Orphan	GPR3	Homo sapiens	Palmitic Acid	-	Gs/β1/γ2	3.49	2024-03-06	doi.org/10.1021/acs.biochem.3c00647
	8U8F (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	Palmitic Acid	-		3.49	2024-03-06	doi.org/10.1021/acs.biochem.3c00647
	8IYX	A	Orphan	Orphan	GPR34	Homo sapiens	YL-365	-	-	3.34	2024-03-20	doi.org/10.1073/pnas.2308435120
	8X2K	A	Orphan	Orphan	GPR3	Homo sapiens	Oleic monoethanolamide	-	chim(NtGi1-Gs)/β1/γ2	3.03	2024-04-03	doi.org/10.1038/s41422-023-00919-8
	8X2K (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	Oleic monoethanolamide	-		3.03	2024-04-03	doi.org/10.1038/s41422-023-00919-8
	8XOF	A	Orphan	Orphan	GPR30	Homo sapiens	Lys05	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.6	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOF (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	Lys05	-		2.6	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOG	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOG (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		2.9	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOH	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOH (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOI	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOI (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		3.2	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOJ	A	Orphan	Orphan	GPR30	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.1	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8XOJ (No Gprot)	A	Orphan	Orphan	GPR30	Homo sapiens	-	-		3.1	2024-04-10	doi.org/10.1038/s41422-024-00963-y
	8IZ4	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (TJR)	-	Gi1/β1/γ2	2.94	2024-04-10	To be published
	8IZ4 (No Gprot)	A	Orphan	Orphan	GPR34	Homo sapiens	Lysophosphatidylserine (TJR)	-		2.94	2024-04-10	To be published
	9LYB	A	Orphan	Orphan	GPR3	Homo sapiens	-	-	Gs/β1/γ2	3.16	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYB (No Gprot)	A	Orphan	Orphan	GPR3	Homo sapiens	-	-		3.16	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYC	A	Orphan	Orphan	GPR3; GPR3	Homo sapiens	-	-	Gs/β1/γ2	3.06	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYC (No Gprot)	A	Orphan	Orphan	GPR3; GPR3	Homo sapiens	-	-		3.06	2025-04-09	doi.org/10.1016/j.celrep.2025.115478
	9LYD	A	Orphan	Orphan	GPR3; GPR3	Homo sapiens	-	-	-	3.66	2025-04-09	doi.org/10.1016/j.celrep.2025.115478

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