psnGPCRdb

Other Proteins → Single PSN

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Show: Click this button to access the corresponding database entry page.

PDB: PDB code of the receptor used to compute the network and a direct link to the corresponding entry in the Protein Data Bank.

Class: Receptor Class.

SubFamily: Receptor Sub Family.

Type: Receptor Type.

Subtype: Receptor SubType.

Species: Organism.

Orthosteric Ligand: Name of the orthosteric ligand, if present.

Other Ligand(s): Name of other allosteric ligands, if present.

Protein Partners: G Protein, Arrestin or Kinase coupled to a given receptor.

Resolution: Structure resolution.

Date: Deposition date.

DOI: DOI and link of the corresponding paper.

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ShowPDBClassSubFamilyTypeSubTypeSpeciesOrthosteric LigandOther Ligand(s)Protein PartnersResolutionDateDOI
4PXFASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-Arrestin1 Finger Loop2.752014-09-17doi.org/10.1038/ncomms5801
4ZWJASensoryOpsinsRhodopsinHomo sapiens--Arrestin13.32015-07-29doi.org/10.1038/nature14656
5DGYASensoryOpsinsRhodopsinHomo sapiens--Arrestin17.72016-03-23doi.org/10.1038/sdata.2016.21
5W0PASensoryOpsinsRhodopsinHomo sapiens--Arrestin13.012017-08-09doi.org/10.1016/j.cell.2017.07.002
6PWCAPeptideNeurotensinNTS1Homo sapiensNeurotensin-(9-13)-Arrestin24.92019-12-04doi.org/10.1038/s41422-019-0256-2
6U1NAAmineAcetylcholine (muscarinic)M2Homo sapiens-LY2119620Arrestin242020-02-26doi.org/10.1038/s41586-020-1954-0
6UP7APeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)-Arrestin24.22020-02-26doi.org/10.1038/s41586-020-1953-1
6TKOAAmineAdrenergicβ1Meleagris gallopavoArformoterol-Arrestin23.32020-06-17doi.org/10.1038/s41586-020-2419-1
7KNTB1PeptideCalcitoninCT LikeHomo sapiens--RAMP13.152021-02-24doi.org/10.1126/science.abf7258
7KNUB1PeptideCalcitoninCT LikeHomo sapiensCalcitonin gene-related peptide-1-RAMP13.492021-02-24doi.org/10.1126/science.abf7258
7MT8ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK15.82021-07-07doi.org/10.1038/s41586-021-03721-x
7MT9ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK172021-07-07doi.org/10.1038/s41586-021-03721-x
7MTAASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK14.12021-07-07doi.org/10.1038/s41586-021-03721-x
7MTBASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK142021-07-07doi.org/10.1038/s41586-021-03721-x
7EWPCOrphanOrphanGPR158; GPR158Homo sapiens--B5; RGS74.32021-12-01doi.org/10.1038/s41467-021-27147-1
7EWRCOrphanOrphanGPR158; GPR158Homo sapiens--B5; RGS74.72021-12-01doi.org/10.1038/s41467-021-27147-1
7SHFCOrphanOrphanGPR158; GPR158Homo sapiens--B5; RGS73.42021-12-01doi.org/10.1126/science.abl4732
7R0CAPeptideVasopressin and OxytocinV2Homo sapiensAVP-Arrestin24.732022-09-14doi.org/10.1126/sciadv.abo7761
7SRSAAmine5-Hydroxytryptamine5-HT2BHomo sapiensLSD-Arrestin23.32022-09-21doi.org/10.1016/j.neuron.2022.08.006
8HS2AOrphanOrphanGPR20Homo sapiens--Fab0463.082023-03-08doi.org/10.1038/s41421-023-00520-8
8JRUB1PeptideGlucagonGlucagonHomo sapiens--Arrestin23.52023-08-16doi.org/10.1038/s41586-023-06420-x
8JRVB1PeptideGlucagonGlucagonHomo sapiensGlucagon-Arrestin23.32023-08-16doi.org/10.1038/s41586-023-06420-x
8WM9FProteinFrizzledFZD4Homo sapiens--DVL-23.532024-09-11doi.org/10.1038/s41467-024-52174-z
8WMAFProteinFrizzledFZD4Homo sapiens--DVL-23.472024-09-11doi.org/10.1038/s41467-024-52174-z
9IJRAOrphanOrphanGPR52Homo sapiens-C17Arrestin23.862025-09-03doi.org/10.1038/s41422-025-01165-w
9IJSAOrphanOrphanGPR52Homo sapiens--Arrestin23.642025-09-03doi.org/10.1038/s41422-025-01165-w
9LXRB1PeptideParathyroid HormonePTH1Homo sapiensLA-PTH Analog-Arrestin23.072025-09-10To be published
9KUVAPeptideApelinApelinHomo sapiensCMPD644-Arrestin23.212025-09-17doi.org/10.1038/s41467-025-62870-z
9KUWAPeptideApelinApelin; ApelinHomo sapiensCMPD644-Arrestin2 ; Arrestin23.492025-09-17doi.org/10.1038/s41467-025-62870-z
9KUXAPeptideApelinApelin; ApelinHomo sapiensCMPD644-Arrestin23.572025-09-17doi.org/10.1038/s41467-025-62870-z
9MBACAminoacidMetabotropic glutamatemGlu8; mGlu8Homo sapiensGlutamate-Arrestin2 ; Arrestin23.142025-10-01doi.org/10.1016/j.molcel.2025.08.019
9KB8AOrphanOrphanLGR4Homo sapiensR-spondin-2-ZNRF3; ZNRF33.252025-10-15doi.org/10.1038/s41467-025-64129-z
9KB9AOrphanOrphanLGR4; LGR4Homo sapiensR-spondin-2-ZNRF3; ZNRF33.592025-10-15doi.org/10.1038/s41467-025-64129-z
9MNIB1PeptideCalcitoninCTLikeHomo sapiensdC2_05-RAMP14.062025-10-22doi.org/10.1101/2025.03.23.644666
9WSVAPeptideOpioidμHomo sapiensDAMGO-Arrestin22.82025-11-2610.1038/s41422-025-01191-8
9WSXAPeptideOpioidμHomo sapiensEndomorphin-Arrestin22.82025-11-2610.1038/s41422-025-01191-8
8WRZALipidCannabinoidCB1Homo sapiensAM841-Arrestin23.62024-02-28AM841
8WU1ALipidCannabinoidCB1Homo sapiensMDMB-Fubinaca-Arrestin23.22024-03-20doi.org/10.1016/j.cell.2023.11.017
8WVUAOrphanOrphanLGR4Homo sapiensR-spondin-1-RNF433.612024-10-30To be published
8XFPAOrphanOrphanLGR4Homo sapiensR-spondin-2-ZNRF3; ZNRF33.212024-12-04doi.org/10.1038/s41467-024-55431-3
8XFSAOrphanOrphanLGR4Homo sapiensR-spondin-2-ZNRF3; ZNRF33.22024-12-04doi.org/10.1038/s41467-024-55431-3
8XFTAOrphanOrphanLGR4Homo sapiensR-spondin-2-ZNRF33.242024-12-04doi.org/10.1038/s41467-024-55431-3
8Y69AOrphanOrphanLGR4; LGR4Homo sapiensR-spondin-2-ZNRF33.382024-12-04doi.org/10.1038/s41467-024-55431-3
9II2CAminoacidMetabotropic GlutamatemGlu3; mGlu3Homo sapiensGlutamate-Arrestin2; Arrestin23.72025-03-05doi.org/10.1038/s41589-025-01858-8
9II3CAminoacidMetabotropic GlutamatemGlu3; mGlu3Homo sapiensGlutamate-Arrestin23.92025-03-05doi.org/10.1038/s41589-025-01858-8
9E82AProteinChemokineACKR3Homo sapiensCXCL12 (fragment)-Arrestin23.42025-04-02doi.org/10.1038/s41586-025-09024-9
8ZYTAPeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)SBI-553Arrestin22.652025-04-09doi.org/10.1038/s41422-025-01095-7
8ZYYAPeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)SBI-553Arrestin22.832025-04-09doi.org/10.1038/s41422-025-01095-7
9M0DAPeptideNeurotensinNTS1Homo sapiens--Arrestin23.412025-04-09doi.org/10.1038/s41422-025-01095-7
8ZYUAPeptideNeurotensinNTS1Homo sapiensNeurotensin-(8-13)SBI-553Arrestin22.652025-04-16doi.org/10.1038/s41422-025-01095-7
9MD1AAmine5-Hydroxytryptamine5-HT1AHomo sapiensBuspironePtdIns4PGz/β1/γ23.032025-08-13doi.org/10.1126/sciadv.adu9851
9UAPAAmineAcetylcholine (muscarinic)M1Homo sapiens--G11(CT)3.622025-10-29To be published
9UCPAAmineAcetylcholine (muscarinic)M1Homo sapiensIperoxo-G11(CT)2.882025-10-29To be published
9ECJANucleotideP2YP2Y8Homo sapiensS-geranylgeranyl-L-glutathione-G13/β1/γ22.92025-11-05To be published
9UYHAProteinChemerinCML2Homo sapiensChemerin-9-Arrestin23.32025-11-1910.1126/science.adt8794
9UYIAProteinChemerinCML2Homo sapiensChemerin-9-Arrestin23.22025-11-1910.1126/science.adt8794
9UYJAProteinChemerinCML2Homo sapiensChemerin-9-Arrestin23.32025-11-1910.1126/science.adt8794
9UYLAProteinChemerinCML2Homo sapiensChemerin-9-Arrestin23.32025-11-1910.1126/science.adt8794
9UYMAProteinChemerinCML2Homo sapiensChemerin-9-chim(Arrestin3-CtArrestin2)3.52025-11-1910.1126/science.adt8794
9UYNAProteinChemerinCML2Homo sapiens--Arrestin22.92025-11-1910.1126/science.adt8794