All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.
Show: Click this button to access the corresponding database entry page.
PDB: PDB code of the receptor used to compute the network and a direct link to the corresponding entry in the Protein Data Bank.
Class: Receptor Class.
SubFamily: Receptor Sub Family.
Type: Receptor Type.
Subtype: Receptor SubType.
Species: Organism.
Orthosteric Ligand: Name of the orthosteric ligand, if present.
Other Ligand(s): Name of other allosteric ligands, if present.
Protein Partners: G Protein, Arrestin or Kinase coupled to a given receptor.
Resolution: Structure resolution.
Date: Deposition date.
DOI: DOI and link of the corresponding paper.
| Show | PDB | Class | SubFamily | Type | SubType | Species | Orthosteric Ligand | Other Ligand(s) | Protein Partners | Resolution | Date | DOI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 9II3 | C | Aminoacid | Metabotropic Glutamate | mGlu3; mGlu3 | Homo sapiens | Glutamate | - | Arrestin2 | 3.9 | 2025-03-05 | doi.org/10.1038/s41589-025-01858-8 | |
| 9II2 | C | Aminoacid | Metabotropic Glutamate | mGlu3; mGlu3 | Homo sapiens | Glutamate | - | Arrestin2 | 3.7 | 2025-03-05 | doi.org/10.1038/s41589-025-01858-8 | |
| 8Y69 | A | Orphan | Orphan | LGR4 | Homo sapiens | R-spondin-2 | Cholesterol | ZNRF3 | 3.38 | 2024-12-04 | To be published | |
| 8XFT | A | Orphan | Orphan | LGR4 | Homo sapiens | R-spondin-2 | - | ZNRF3 | 3.24 | 2024-12-04 | To be published | |
| 8XFS | A | Orphan | Orphan | LGR4 | Homo sapiens | R-spondin-2 | - | ZNRF3 | 3.2 | 2024-12-04 | To be published | |
| 8XFP | A | Orphan | Orphan | LGR4 | Homo sapiens | R-spondin-2 | - | ZNRF3 | 3.21 | 2024-12-04 | To be published | |
| 8WVU | A | Orphan | Orphan | LGR4 | Homo sapiens | R-spondin-1 | - | RNF43 | 3.61 | 2024-10-30 | To be published | |
| 8WU1 | A | Lipid | Cannabinoid | CB1 | Homo sapiens | PubChem 119025665 | - | Arrestin2 | 3.2 | 2024-03-20 | To be published | |
| 8WRZ | A | Lipid | Cannabinoid | CB1 | Homo sapiens | PubChem 102336704 | - | Arrestin2 | 3.6 | 2024-02-28 | 10.1093/procel/pwad055 | |
| 8JRV | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | Glucagon | - | Arrestin2 | 3.3 | 2023-08-16 | 10.1038/s41586-023-06420-x | |
| 8JRU | B1 | Peptide | Glucagon | Glucagon | Homo sapiens | - | - | Arrestin2 | 3.5 | 2023-08-16 | 10.1038/s41586-023-06420-x | |
| 7SRS | A | Amine | 5-Hydroxytryptamine | 5-HT2B | Homo sapiens | LSD | - | Arrestin2 | 3.3 | 2022-09-21 | 10.1016/j.neuron.2022.08.006 | |
| 7R0C | A | Peptide | Vasopressin and Oxytocin | V2 | Homo sapiens | AVP | - | Arrestin2 | 4.73 | 2022-09-14 | 10.1126/sciadv.abo7761 | |
| 7SHF | C | Orphan | Orphan | GPR158 | Homo sapiens | - | PI; PE | B5; RGS7 | 3.4 | 2021-12-01 | 10.1126/science.abl4732 | |
| 7EWR | C | Orphan | Orphan | GPR158 | Homo sapiens | - | - | B5; RGS7 | 4.7 | 2021-12-01 | 10.1038/s41467-021-27147-1 | |
| 7EWP | C | Orphan | Orphan | GPR158 | Homo sapiens | - | - | B5; RGS7 | 4.3 | 2021-12-01 | 10.1038/s41467-021-27147-1 | |
| 7MTB | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-Retinal | - | GRK1 | 4 | 2021-07-07 | 10.1038/s41586-021-03721-x | |
| 7MTA | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-Retinal | - | GRK1 | 4.1 | 2021-07-07 | 10.1038/s41586-021-03721-x | |
| 7MT9 | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-Retinal | - | GRK1 | 7 | 2021-07-07 | 10.1038/s41586-021-03721-x | |
| 7MT8 | A | Sensory | Opsins | Rhodopsin | Bos taurus | All-trans-Retinal | - | GRK1 | 5.8 | 2021-07-07 | 10.1038/s41586-021-03721-x | |
| 7KNU | B1 | Peptide | Calcitonin | CT Like | Homo sapiens | Calcitonin gene-related peptide-1 | - | RAMP1 | 3.49 | 2021-02-24 | 10.1126/science.abf7258 | |
| 7KNT | B1 | Peptide | Calcitonin | CT Like | Homo sapiens | - | - | RAMP1 | 3.15 | 2021-02-24 | 10.1126/science.abf7258 | |
| 6TKO | A | Amine | Adrenergic | β1 | Meleagris gallopavo | Arformoterol | - | Arrestin2 | 3.3 | 2020-06-17 | 10.1038/s41586-020-2419-1 | |
| 6U1N | A | Amine | Acetylcholine (muscarinic) | M2 | Homo sapiens | - | LY2119620 | Arrestin2 | 4 | 2020-02-26 | 10.1038/s41586-020-1954-0 | |
| 6UP7 | A | Peptide | Neurotensin | NTS1 | Homo sapiens | Neurotensin | - | Arrestin2 | 4.2 | 2020-02-26 | 10.1038/s41586-020-1953-1 | |
| 6PWC | A | Peptide | Neurotensin | NTS1 | Homo sapiens | Neurotensin | - | Arrestin2 | 4.9 | 2019-12-04 | 10.1038/s41422-019-0256-2 | |
| 5W0P | A | Sensory | Opsins | Rhodopsin | Homo sapiens | - | - | Arrestin1 | 3.01 | 2017-08-09 | 10.1016/j.cell.2017.07.002 | |
| 5DGY | A | Sensory | Opsins | Rhodopsin | Homo sapiens | - | - | Arrestin1 | 7.7 | 2016-03-23 | 10.1038/sdata.2016.21 | |
| 4ZWJ | A | Sensory | Opsins | Rhodopsin | Homo sapiens | - | - | Arrestin1 | 3.3 | 2015-07-29 | 10.1038/nature14656 | |
| 4PXF | A | Sensory | Opsins | Rhodopsin | Bos taurus | Octyl-β-D-Glucopyranoside | - | Arrestin1 Finger Loop | 2.75 | 2014-09-17 | 10.1038/ncomms5801 |