psnGPCR

Receptors → Single PSN

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Show: Click this button to access the corresponding database entry page.

PDB: PDB code of the receptor used to compute the network and a direct link to the corresponding entry in the Protein Data Bank.

Class: Receptor Class.

SubFamily: Receptor Sub Family.

Type: Receptor Type.

Subtype: Receptor SubType.

Species: Organism.

Orthosteric Ligand: Name of the orthosteric ligand, if present.

Other Ligand(s): Name of other allosteric ligands, if present.

Protein Partners: G Protein, Arrestin or Kinase coupled to a given receptor.

Resolution: Structure resolution.

Date: Deposition date.

DOI: DOI and link of the corresponding paper.

PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
7E2X	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3	2021-04-14	10.1038/s41586-021-03376-8
7E2Y	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Serotonin	-	Gi1/&β;1/&γ;2	3	2021-04-14	10.1038/s41586-021-03376-8
7E2Z	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Aripiprazole	-	Gi1/&β;1/&γ;2	3.1	2021-04-14	10.1038/s41586-021-03376-8
8JSP	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Ulotaront	-	Gi1/&β;1/&γ;2	3.65	2023-11-15	10.1038/s41586-023-06804-z
8JT6	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	(R)-IHCH-7179	-	Gi1/&β;1/&γ;2	3	2024-02-28	To be published
8W8B	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	SEP-363856	-	Gi1/&β;1/&γ;2	3	2023-11-22	10.1038/s41586-023-06775-1
4IAQ	A	Amine	5-Hydroxytryptamine	5-HT_1B	Homo sapiens	Dihydroergotamine	-	-	2.8	2013-03-13	10.1126/science.1232807
4IAR	A	Amine	5-Hydroxytryptamine	5-HT_1B	Homo sapiens	Ergotamine	-	-	2.7	2013-03-13	10.1126/science.1232807
5V54	A	Amine	5-Hydroxytryptamine	5-HT_1B	Homo sapiens	Methiothepin	-	-	3.9	2018-02-07	10.1038/s41421-018-0009-2
6G79	A	Amine	5-Hydroxytryptamine	5-HT_1B	Homo sapiens	Donitriptan	-	Go/&β;1/&γ;2	3.78	2018-06-20	10.1038/s41586-018-0241-9
7C61	A	Amine	5-Hydroxytryptamine	5-HT_1B	Homo sapiens	Ergotamine	-	-	3	2020-07-29	10.1038/s41598-020-68355-x
7E32	A	Amine	5-Hydroxytryptamine	5-HT_1D	Homo sapiens	Serotonin	-	Gi1/&β;1/&γ;2	2.9	2021-04-21	10.1038/s41586-021-03376-8
7E33	A	Amine	5-Hydroxytryptamine	5-HT_1E	Homo sapiens	BRL-54443	-	Gi1/&β;1/&γ;2	2.9	2021-04-14	10.1038/s41586-021-03376-8
7EXD	A	Amine	5-Hydroxytryptamine	5-HT_1F	Homo sapiens	Lasmiditan	-	Gi1/&β;1/&γ;2	3.4	2021-08-04	10.1038/s41422-021-00527-4
6A93	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Risperidone	-	-	3	2019-02-13	10.1038/s41594-018-0180-z
6A94	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Zotepine	-	-	2.9	2019-02-13	10.1038/s41594-018-0180-z
6WGT	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	LSD	-	-	3.4	2020-09-23	10.1016/j.cell.2020.08.024
6WH4	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Methiothepin	-	-	3.4	2020-09-23	10.1016/j.cell.2020.08.024
6WHA	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	DB13948	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.36	2020-09-23	10.1016/j.cell.2020.08.024
7RAN	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	PubChem 164575847	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.45	2022-07-06	10.1038/s41586-022-05258-z
7VOD	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Cariprazine	-	-	3.3	2021-12-22	10.1038/s41593-021-00971-w
7VOE	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Aripiprazole	-	-	2.9	2021-12-22	10.1038/s41593-021-00971-w
7WC4	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Serotonin	-	-	3.2	2022-01-26	10.1126/science.abl8615
7WC5	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Psilocin	-	-	3.2	2022-01-26	10.1126/science.abl8615
7WC6	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	LSD	-	-	2.6	2022-01-26	10.1126/science.abl8615
7WC7	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Lisuride	-	-	2.6	2022-01-26	10.1126/science.abl8615
7WC8	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Lumateperone	-	-	2.45	2022-01-26	10.1126/science.abl8615
7WC9	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	PubChem 162421364	-	-	2.5	2022-01-26	10.1126/science.abl8615
8JT8	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	(R)-IHCH-7179	-	-	2.7	2024-02-28	To be published
4IB4	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	Ergotamine	-	-	2.7	2013-03-13	10.1126/science.1232808
4NC3	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	Ergotamine	-	-	2.8	2013-12-18	10.1126/science.1244142
5TUD	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	Ergotamine	-	-	3	2017-07-26	10.1073/pnas.1700891114
5TVN	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	LSD	-	-	2.9	2017-02-01	10.1016/j.cell.2016.12.033
6DRX	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	Lisuride	-	-	3.1	2018-08-29	10.1038/s41594-018-0116-7
6DRY	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	Methylergonovine	-	-	2.92	2018-08-29	10.1038/s41594-018-0116-7
6DRZ	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	Methysergide	-	-	3.1	2018-08-29	10.1038/s41594-018-0116-7
6DS0	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	Ly266097	-	-	3.19	2018-08-29	10.1038/s41594-018-0116-7
7SRQ	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	LSD	-	-	2.7	2022-09-21	10.1016/j.neuron.2022.08.006
7SRR	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	LSD	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.9	2022-09-21	10.1016/j.neuron.2022.08.006
7SRS	A	Amine	5-Hydroxytryptamine	5-HT_2B	Homo sapiens	LSD	-	Arrestin2	3.3	2022-09-21	10.1016/j.neuron.2022.08.006
6BQG	A	Amine	5-Hydroxytryptamine	5-HT_2C	Homo sapiens	Ergotamine	-	-	3	2018-02-14	10.1016/j.cell.2018.01.001
6BQH	A	Amine	5-Hydroxytryptamine	5-HT_2C	Homo sapiens	Ritanserin	-	-	2.7	2018-02-14	10.1016/j.cell.2018.01.001
8DPF	A	Amine	5-Hydroxytryptamine	5-HT_2C	Homo sapiens	Lorcaserin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.84	2022-08-24	10.1016/j.celrep.2022.111211
8DPG	A	Amine	5-Hydroxytryptamine	5-HT_2C	Homo sapiens	Psilocin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.6	2022-08-24	10.1016/j.celrep.2022.111211
8DPH	A	Amine	5-Hydroxytryptamine	5-HT_2C	Homo sapiens	Lorcaserin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.2	2022-08-24	10.1016/j.celrep.2022.111211
8DPI	A	Amine	5-Hydroxytryptamine	5-HT_2C	Homo sapiens	Lorcaserin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.4	2022-08-24	10.1016/j.celrep.2022.111211
7XT8	A	Amine	5-Hydroxytryptamine	5-HT₄	Homo sapiens	Serotonin	-	Gs/&β;1/&γ;2	3.1	2022-07-27	10.1016/j.molcel.2022.05.031
7XT9	A	Amine	5-Hydroxytryptamine	5-HT₄	Homo sapiens	Serotonin	-	Gs/&β;1/&γ;2	3.2	2022-07-27	10.1016/j.molcel.2022.05.031
7XTA	A	Amine	5-Hydroxytryptamine	5-HT₄	Homo sapiens	Serotonin	-	Gi1/&β;1/&γ;2	3.2	2022-07-27	10.1016/j.molcel.2022.05.031
7UM4	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	AS2674723	-	-	2.8	2022-07-20	10.1038/s41594-022-00796-6
7UM5	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	chim(NtGi1-Go)/&β;1/&γ;2	2.73	2022-07-20	10.1038/s41594-022-00796-6
7UM6	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	Lisuride	-	chim(NtGi1-Go)/&β;1/&γ;2	2.79	2022-07-20	10.1038/s41594-022-00796-6
7UM7	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	Methylergometrine	-	chim(NtGi1-Go)/&β;1/&γ;2	2.75	2022-07-20	10.1038/s41594-022-00796-6
7X5H	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	Gi1/&β;1/&γ;2	3.1	2022-09-14	10.1038/s41421-022-00412-3
7XTB	A	Amine	5-Hydroxytryptamine	5-HT₆	Homo sapiens	Serotonin	-	Gs/&β;1/&γ;2	3.3	2022-07-27	10.1016/j.molcel.2022.05.031
7YS6	A	Amine	5-Hydroxytryptamine	5-HT₆	Homo sapiens	Serotonin	-	chim(NtGi1-Gs)/&β;1/&γ;2	3	2023-03-29	10.1073/pnas.2209917120
8JLZ	A	Amine	5-Hydroxytryptamine	5-HT₆	Homo sapiens	ST1936	-	Gs/&β;1/&γ;2	3.09	2023-06-28	10.1016/j.bbrc.2023.05.126
7XTC	A	Amine	5-Hydroxytryptamine	5-HT₇	Homo sapiens	5-CT	-	Gs/&β;1/&γ;2	3.2	2022-07-27	10.1016/j.molcel.2022.05.031
5N2S	A	Nucleotide	Adenosine	A₁	Homo sapiens	PSB36	-	-	3.3	2017-07-26	10.1016/j.str.2017.06.012
5UEN	A	Nucleotide	Adenosine	A₁	Homo sapiens	DU172	-	-	3.2	2017-03-01	10.1016/j.cell.2017.01.042
6D9H	A	Nucleotide	Adenosine	A₁	Homo sapiens	Adenosine	-	Gi2/&β;1/&γ;2	3.6	2018-06-20	10.1038/s41586-018-0236-6
7LD3	A	Nucleotide	Adenosine	A₁	Homo sapiens	Adenosine	PubChem 25263603	Gi2/&β;1/&γ;2	3.2	2021-09-08	10.1038/s41586-021-03897-2
7LD4	A	Nucleotide	Adenosine	A₁	Homo sapiens	Adenosine	-	Gi2/&β;1/&γ;2	3.3	2021-09-08	10.1038/s41586-021-03897-2
2YDO	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Adenosine	-	-	3	2011-05-18	10.1038/nature10136
2YDV	A	Nucleotide	Adenosine	A_2A	Homo sapiens	NECA	-	-	2.6	2011-05-18	10.1038/nature10136
3EML	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	2.6	2008-10-14	10.1126/science.1164772
3PWH	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	3.3	2011-09-07	10.1016/j.str.2011.06.014
3QAK	A	Nucleotide	Adenosine	A_2A	Homo sapiens	UK-432097	-	-	2.71	2011-03-09	10.1126/science.1202793
3REY	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 5697	-	-	3.31	2011-09-07	10.1016/j.str.2011.06.014
3RFM	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Caffeine	-	-	3.6	2011-09-07	10.1016/j.str.2011.06.014
3UZA	A	Nucleotide	Adenosine	A_2A	Homo sapiens	GTPL9236	-	-	3.27	2012-03-21	10.1021/jm201376w
3UZC	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 135566609	-	-	3.34	2012-03-21	10.1021/jm201376w
3VG9	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Antibody	-	2.7	2012-02-01	10.1038/nature10750
3VGA	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Antibody	-	3.1	2012-02-01	10.1038/nature10750
4EIY	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.8	2012-07-25	10.1126/science.1219218
4UG2	A	Nucleotide	Adenosine	A_2A	Homo sapiens	CGS21680	-	-	2.6	2015-04-08	10.1124/mol.114.097360
4UHR	A	Nucleotide	Adenosine	A_2A	Homo sapiens	CGS21680	-	-	2.6	2015-04-08	10.1124/mol.114.097360
5G53	A	Nucleotide	Adenosine	A_2A	Homo sapiens	NECA	-	Gs	3.4	2016-08-03	10.1038/nature18966
5IU4	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.72	2016-06-29	10.1021/acs.jmedchem.6b00653
5IU7	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Q27456346	Na	-	1.9	2016-06-29	10.1021/acs.jmedchem.6b00653
5IU8	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Q27456347	Na	-	2	2016-06-29	10.1021/acs.jmedchem.6b00653
5IUA	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Q27456348	Na	-	2.2	2016-06-29	10.1021/acs.jmedchem.6b00653
5IUB	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Q27456344	Na	-	2.1	2016-06-29	10.1021/acs.jmedchem.6b00653
5JTB	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	2.8	2017-05-31	10.1126/sciadv.1602952
5K2A	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2.5	2016-09-21	10.1126/sciadv.1600292
5K2B	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2.5	2016-09-21	10.1126/sciadv.1600292
5K2C	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.9	2016-09-21	10.1126/sciadv.1600292
5K2D	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	1.9	2016-09-21	10.1126/sciadv.1600292
5MZJ	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Theophylline	Na	-	2	2017-07-26	10.1016/j.str.2017.06.012
5MZP	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Caffeine	Na	-	2.1	2017-07-26	10.1016/j.str.2017.06.012
5N2R	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 92460631; psb36	Na	-	2.8	2017-07-26	10.1016/j.str.2017.06.012
5NLX	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2.14	2017-09-27	10.1038/s41467-017-00630-4
5NM2	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.95	2017-09-27	10.1038/s41467-017-00630-4
5NM4	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.7	2017-09-27	10.1038/s41467-017-00630-4
5OLG	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.87	2018-01-17	10.1038/s41598-017-18570-w
5OLH	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Vipadenant	Na	-	2.6	2018-01-17	10.1038/s41598-017-18570-w
5OLO	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Tozadenant	Na	-	3.1	2018-01-17	10.1038/s41598-017-18570-w
5OLV	A	Nucleotide	Adenosine	A_2A	Homo sapiens	LUAA41063	Na	-	2	2018-01-17	10.1038/s41598-017-18570-w
5OLZ	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 135566609	Na	-	1.9	2018-01-17	10.1038/s41598-017-18570-w
5OM1	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 135566609	Na	-	2.1	2018-01-17	10.1038/s41598-017-18570-w
5OM4	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 135566609	Na	-	2	2018-01-17	10.1038/s41598-017-18570-w
5UIG	A	Nucleotide	Adenosine	A_2A	Homo sapiens	J3.651.884G	-	-	3.5	2017-02-08	10.1073/pnas.1621423114
5UVI	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	3.2	2017-05-24	10.1107/S205225251700570X
5VRA	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2.35	2017-12-13	10.1038/nprot.2017.135
5WF5	A	Nucleotide	Adenosine	A_2A	Homo sapiens	UK-432097	-	-	2.6	2018-02-21	10.1016/j.str.2017.12.013
5WF6	A	Nucleotide	Adenosine	A_2A	Homo sapiens	UK-432097	-	-	2.9	2018-02-21	10.1016/j.str.2017.12.013
6AQF	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	2.51	2018-01-10	10.1016/j.cell.2017.12.004
6GDG	A	Nucleotide	Adenosine	A_2A	Homo sapiens	NECA	-	Gs/&β;1/&γ;1	4.11	2018-05-16	10.7554/eLife.35946
6GT3	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Imaradenant	Na	-	2	2019-06-26	10.1136/jitc-2019-000417
6JZH	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2.25	2019-10-30	10.1107/S1600576719012846
6LPJ	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.8	2020-11-25	10.1038/s41598-020-76277-x
6LPK	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.8	2020-11-25	10.1038/s41598-020-76277-x
6LPL	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2	2020-11-25	10.1038/s41598-020-76277-x
6MH8	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	4.2	2019-04-24	10.1107/S205225251900263X
6PS7	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	1.85	2019-11-13	10.1107/S2052252519013137
6S0L	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	2.65	2020-07-15	10.1107/S2052252520011379
6S0Q	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	2.65	2020-07-15	10.1107/S2052252520011379
6WQA	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2	2020-11-18	10.1107/S2052252520012701
6ZDR	A	Nucleotide	Adenosine	A_2A	Homo sapiens	HMS1413f12	Na	-	1.92	2020-09-16	10.1002/anie.202003788
6ZDV	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 984073	Na	-	2.13	2020-09-16	10.1002/anie.202003788
7ARO	A	Nucleotide	Adenosine	A_2A	Homo sapiens	LUF5833	Na	-	3.12	2021-04-07	10.1021/acs.jmedchem.0c01856
7EZC	A	Nucleotide	Adenosine	A_2A	Homo sapiens	UKA	-	-	3.8	2022-04-13	10.1107/S2052252522001907
7PX4	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PSB-2113	-	-	2.25	2022-03-02	10.1002/anie.202115545
7PYR	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PSB-2115	-	-	2.6	2022-03-02	10.1002/anie.202115545
7RM5	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2.79	2021-09-08	10.1073/pnas.2106041118
7T32	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	-	-	3.4	2022-08-10	10.1038/s41467-022-32125-2
8A2O	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Theophylline	Na	-	3.45	2023-08-30	10.1107/S1600576723006428
8A2P	A	Nucleotide	Adenosine	A_2A	Homo sapiens	LUAA47070	Na	-	3.5	2023-08-30	10.1107/S1600576723006428
8C9W	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Etrumadenant	-	-	2.11	2023-07-12	10.1038/s42004-023-00894-6
8CIC	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Etrumadenant	Na	-	2.1	2023-05-31	10.1038/s42004-023-00894-6
8CU6	A	Nucleotide	Adenosine	A_2A	Homo sapiens	LJ-4517	-	-	2.8	2022-08-31	10.1021/acs.jmedchem.2c00462
8CU7	A	Nucleotide	Adenosine	A_2A	Homo sapiens	LJ-4517	Na	-	2.05	2022-08-31	10.1021/acs.jmedchem.2c00462
8DU3	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 105526064	-	-	2.5	2022-08-10	10.1016/j.ejmech.2022.114620
8FYN	A	Nucleotide	Adenosine	A_2A	Homo sapiens	ZM241385	Na	-	2	2023-03-08	10.1038/s41467-023-36733-4
8GNE	A	Nucleotide	Adenosine	A_2A	Homo sapiens	KW-6356	Na	-	2.3	2023-03-22	10.1124/molpharm.122.000633
8GNG	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Istradefylline	-	-	3.2	2023-03-22	10.1124/molpharm.122.000633
8JWY	A	Nucleotide	Adenosine	A_2A	Homo sapiens	PubChem 168451710	-	-	2.33	2023-08-16	10.1007/s11427-023-2459-8
8JWZ	A	Nucleotide	Adenosine	A_2A	Homo sapiens	AB928	Na	-	2.37	2023-08-16	10.1007/s11427-023-2459-8
8PWN	A	Nucleotide	Adenosine	A_2A	Homo sapiens	Theophylline	-	-	2.75	2023-10-25	10.1038/s42004-023-01014-0
7XY6	A	Nucleotide	Adenosine	A_2B	Homo sapiens	PubChem 11717831	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.99	2023-05-03	10.1126/sciadv.add3709
7XY7	A	Nucleotide	Adenosine	A_2B	Homo sapiens	NECA	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.26	2023-05-03	10.1126/sciadv.add3709
8HDO	A	Nucleotide	Adenosine	A_2B	Homo sapiens	BAY 60-6583	-	Gs/&β;1/&γ;2	2.87	2023-01-18	10.1038/s41421-022-00503-1
8HDP	A	Nucleotide	Adenosine	A_2B	Homo sapiens	Adenosine	-	Gs/&β;1/&γ;2	3.2	2023-01-18	10.1038/s41421-022-00503-1
8X16	A	Nucleotide	Adenosine	A3A	Homo sapiens	Piclidenoson	-	Gi1/&β;1/&γ;2	3.29	2024-04-24	10.1038/s41467-024-47207-6
8X17	A	Nucleotide	Adenosine	A3A	Homo sapiens	Namodenoson	-	Gi1/&β;1/&γ;2	3.19	2024-04-24	10.1038/s41467-024-47207-6
7SK3	A	Protein	Chemokine	ACKR3	Homo sapiens	CXCL12	-	-	3.8	2022-07-27	10.1126/sciadv.abn8063
7SK4	A	Protein	Chemokine	ACKR3	Homo sapiens	CXCL12_LRHQ	-	-	3.3	2022-07-27	10.1126/sciadv.abn8063
7SK5	A	Protein	Chemokine	ACKR3	Homo sapiens	CXCL12	-	-	4	2022-07-27	10.1126/sciadv.abn8063
7SK6	A	Protein	Chemokine	ACKR3	Homo sapiens	CXCL12_LRHQ	-	-	4	2022-07-27	10.1126/sciadv.abn8063
7SK7	A	Protein	Chemokine	ACKR3	Homo sapiens	CXCL12	CCX662	-	3.3	2022-07-27	10.1126/sciadv.abn8063
7SK8	A	Protein	Chemokine	ACKR3	Homo sapiens	CXCL12	CCX662	-	3.3	2022-07-27	10.1126/sciadv.abn8063
7SK9	A	Protein	Chemokine	ACKR3	Homo sapiens	-	CCX662	-	3.7	2022-07-27	10.1126/sciadv.abn8063
7EPT	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/&β;1/&γ;2	3	2022-05-11	10.1038/s41586-022-04619-y
7WU2	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/&β;1/&γ;1	2.8	2022-04-27	10.1038/s41586-022-04580-w
7YDH	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi2-G13)/&β;1/&γ;2	3.1	2023-07-12	10.1016/j.chembiol.2023.08.003
7YDJ	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1-G12)/&β;1/&γ;2	3.03	2023-07-12	To be published
7YDM	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.89	2023-07-12	10.1016/j.chembiol.2023.08.003
7YDP	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2023-07-12	10.1016/j.chembiol.2023.08.003
8IKJ	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	-	3.2	2024-02-14	10.1016/j.molcel.2023.12.020
8IKL	B2	Adhesion	Adhesion	ADGRE5	Homo sapiens	-	-	chim(NtGi1L-G13)/&β;1/&γ;2	2.33	2024-01-24	10.1016/j.molcel.2023.12.020
7WU3	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gs/&β;1/&γ;2	3.1	2022-04-27	10.1038/s41586-022-04580-w
7WU4	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/&β;1/&γ;2	3.4	2022-04-27	10.1038/s41586-022-04580-w
7WU5	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	K6G	Gi1/&β;1/&γ;2	3	2022-04-27	10.1038/s41586-022-04580-w
7WXU	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.85	2022-09-28	10.1038/s41467-022-33173-4
7WXW	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.84	2022-09-28	10.1038/s41467-022-33173-4
7WY0	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1L-G13)/&β;1/&γ;2	2.83	2022-09-28	10.1038/s41467-022-33173-4
7WZ7	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	chim(NtGi1-G12)/&β;1/&γ;2	2.83	2022-09-28	10.1038/s41467-022-33173-4
7X2V	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.09	2022-09-28	10.1038/s41467-022-33173-4
8G2Y	B2	Adhesion	Adhesion	ADGRF1	Homo sapiens	-	LPC	chim(Gs-CtGq)/&β;1/&γ;2	3.44	2023-05-10	10.1038/s41467-023-38083-7
7SF8	B2	Adhesion	Adhesion	ADGRG1	Homo sapiens	-	-	chim(NtGi2-G13)/&β;1/&γ;2	2.7	2022-04-27	10.1038/s41586-022-04575-7
7WUI	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	IP15	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2022-04-27	10.1038/s41586-022-04590-8
7WUQ	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-	Gs/&β;1/&γ;2	2.9	2022-04-27	10.1038/s41586-022-04590-8
7XKD	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	Betahydroxyandrosterone	-	Gs/&β;1/&γ;2	2.4	2022-08-10	10.1038/s41589-022-01084-6
7XKE	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	Betahydroxyandrosterone	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2022-08-10	10.1038/s41589-022-01084-6
7XKF	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	Betahydroxyandrosterone	-	Gs/&β;1/&γ;2	2.4	2022-08-10	10.1038/s41589-022-01084-6
7YP7	B2	Adhesion	Adhesion	ADGRG2	Mus musculus	-	-	Gs/&β;1/&γ;2	3.1	2022-08-24	10.1038/s41589-022-01084-6
7D76	B2	Adhesion	Adhesion	ADGRG3	Homo sapiens	Beclomethasone	-	Go/&β;1/&γ;2	3.1	2021-02-03	10.1038/s41586-020-03083-w
7D77	B2	Adhesion	Adhesion	ADGRG3	Homo sapiens	Hydrocortisone	-	Go/&β;1/&γ;2	2.9	2021-02-03	10.1038/s41586-020-03083-w
7WUJ	B2	Adhesion	Adhesion	ADGRG4	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.3	2022-04-27	10.1038/s41586-022-04590-8
7EQ1	B2	Adhesion	Adhesion	ADGRG5	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.3	2022-05-11	10.1038/s41586-022-04619-y
7SF7	B2	Adhesion	Adhesion	ADGRL3	Homo sapiens	-	-	chim(NtGi2-G13)/&β;1/&γ;2	2.9	2022-04-27	10.1038/s41586-022-04575-7
7WY5	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.83	2022-10-26	10.1016/j.molcel.2022.10.009
7WY8	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.83	2022-10-26	10.1016/j.molcel.2022.10.009
7WYB	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	Gi1/&β;1/&γ;2	2.97	2022-10-26	10.1016/j.molcel.2022.10.009
7X10	B2	Adhesion	Adhesion	ADGRL3	Mus musculus	-	-	chim(NtGi1-G12)/&β;1/&γ;2	2.93	2022-10-26	10.1016/j.molcel.2022.10.009
8JMT	B2	Adhesion	Adhesion	ADGRL3	Homo sapiens	-	-	-	3.3	2023-09-06	10.1038/s41589-023-01389-0
7YM8	A	Amine	Adrenergic	Alpha1A	Homo sapiens	Oxymetazoline	-	chim(Gs-CtGq)/&β;1/&γ;2	2.92	2023-07-05	10.1038/s41467-023-39310-x
7YMH	A	Amine	Adrenergic	Alpha1A	Homo sapiens	Norepinephrine	-	chim(Gs-CtGq)/&β;1/&γ;2	3.52	2023-07-05	10.1038/s41467-023-39310-x
7YMJ	A	Amine	Adrenergic	Alpha1A	Homo sapiens	Tamsulosin	-	-	3.35	2023-07-05	10.1038/s41467-023-39310-x
8HN1	A	Amine	Adrenergic	Alpha1A	Homo sapiens	Toxin AdTx1	-	-	2.9	2023-12-20	To be published
8THK	A	Amine	Adrenergic	Alpha1A	Homo sapiens	A61603	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.6	2023-08-16	10.1038/s41467-023-40524-2
8THL	A	Amine	Adrenergic	Alpha1A	Homo sapiens	Epinephrine	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.1	2023-08-16	10.1038/s41467-023-40524-2
7B6W	A	Amine	Adrenergic	α_1b	Homo sapiens	Cyclazosin	-	-	2.87	2022-01-12	10.1038/s41467-021-27911-3
6KUX	A	Amine	Adrenergic	α_2a	Homo sapiens	RS-79948	-	-	2.7	2019-12-04	10.1038/nature06325
6KUY	A	Amine	Adrenergic	α_2a	Homo sapiens	PubChem 145704643	-	-	3.2	2019-12-04	10.1038/nature06325
7EJ0	A	Amine	Adrenergic	α_2a	Homo sapiens	L-Norepinephrine	-	Go/&β;1/&γ;2	3.2	2022-04-13	10.1126/sciadv.abj5347
7EJ8	A	Amine	Adrenergic	α_2a	Homo sapiens	Brimonidine	-	Go/&β;1/&γ;2	3	2022-04-13	10.1126/sciadv.abj5347
7EJA	A	Amine	Adrenergic	α_2a	Homo sapiens	Dexmedetomidine	-	Go/&β;1/&γ;2	3.6	2022-04-13	10.1126/sciadv.abj5347
7EJK	A	Amine	Adrenergic	α_2a	Homo sapiens	Oxymetazoline	-	Go/&β;1/&γ;2	3.4	2022-04-13	10.1126/sciadv.abj5347
7W6P	A	Amine	Adrenergic	α_2a	Homo sapiens	W96	-	Go/&β;1/&γ;2	3.47	2022-09-28	10.1126/science.abn7065
7W7E	A	Amine	Adrenergic	α_2a	Homo sapiens	W58	-	Go/&β;1/&γ;2	3.4	2022-09-28	10.1126/science.abn7065
6K41	A	Amine	Adrenergic	α_2b	Homo sapiens	Dexmedetomidine	-	Go/&β;1/&γ;2	2.9	2020-04-15	10.1038/s41589-020-0492-2
6K42	A	Amine	Adrenergic	α_2b	Homo sapiens	Dexmedetomidine	-	Gi1/&β;1/&γ;2	4.1	2020-04-15	10.1038/s41589-020-0492-2
6KUW	A	Amine	Adrenergic	α_2c	Homo sapiens	PubChem 57213234	-	-	2.8	2019-12-04	10.1038/nature06325
5VBL	A	Peptide	Apelin	Apelin	Homo sapiens	Apelin Mimetic Peptide Agonist	-	-	2.6	2017-05-31	10.1016/j.str.2017.04.008
6KNM	A	Peptide	Apelin	Apelin	Homo sapiens	JN241-9	-	-	3.2	2020-01-29	10.1126/sciadv.aax7379
7SUS	A	Peptide	Apelin	Apelin	Homo sapiens	PubChem 122701908	-	-	2.7	2022-07-27	10.1038/s41594-022-00797-5
7W0L	A	Peptide	Apelin	Apelin	Homo sapiens	PubChem 122701908	-	Gi1/&β;1/&γ;2	3.57	2022-07-27	10.1038/s41594-022-00797-5
7W0M	A	Peptide	Apelin	Apelin	Homo sapiens	PubChem 122701908	-	Gi1/&β;1/&γ;2	3.71	2022-07-27	10.1038/s41594-022-00797-5
7W0N	A	Peptide	Apelin	Apelin	Homo sapiens	Elabela	-	Gi1/&β;1/&γ;2	4.21	2022-07-27	10.1038/s41594-022-00797-5
7W0O	A	Peptide	Apelin	Apelin	Homo sapiens	Elabela	-	Gi1/&β;1/&γ;2	3.78	2022-07-27	10.1038/s41594-022-00797-5
7W0P	A	Peptide	Apelin	Apelin	Homo sapiens	Elabela	-	Gi1/&β;1/&γ;2	3.16	2022-07-27	10.1038/s41594-022-00797-5
8XZF	A	Peptide	Apelin	Apelin	Homo sapiens	WN561	-	Gi1/&β;1/&γ;2	3	2024-03-20	10.1016/j.cell.2024.02.004
8XZG	A	Peptide	Apelin	Apelin	Homo sapiens	Apelin-13	-	Gi1/&β;1/&γ;2	3.2	2024-03-20	10.1016/j.cell.2024.02.004
8XZH	A	Peptide	Apelin	Apelin	Homo sapiens	MM07	-	Gi1/&β;1/&γ;2	2.06	2024-03-20	10.1016/j.cell.2024.02.004
8XZJ	A	Peptide	Apelin	Apelin	Homo sapiens	WN353	-	Gi1/&β;1/&γ;2	3	2024-03-20	10.1016/j.cell.2024.02.004
4YAY	A	Peptide	Angiotensin	AT₁	Homo sapiens	ZD-7155	-	-	2.9	2015-04-22	10.1016/j.cell.2015.04.011
4ZUD	A	Peptide	Angiotensin	AT₁	Homo sapiens	Olmesartan	-	-	2.8	2015-10-07	10.1074/jbc.M115.689000
6DO1	A	Peptide	Angiotensin	AT₁	Homo sapiens	Angiotensin-Like peptide S1I8	-	-	2.9	2019-01-30	10.1016/j.cell.2018.12.006
6OS0	A	Peptide	Angiotensin	AT₁	Homo sapiens	Angiotensinogen	-	-	2.9	2020-02-19	10.1126/science.aay9813
6OS1	A	Peptide	Angiotensin	AT₁	Homo sapiens	TRV026	-	-	2.79	2020-02-19	10.1126/science.aay9813
6OS2	A	Peptide	Angiotensin	AT₁	Homo sapiens	TRV026	-	-	2.7	2020-02-19	10.1126/science.aay9813
7F6G	A	Peptide	Angiotensin	AT₁	Homo sapiens	SAR1-AngII	-	Gq/&β;1/&γ;2	2.9	2023-03-29	10.15252/embj.2022112940
5UNF	A	Peptide	Angiotensin	AT₂	Homo sapiens	PubChem 15780052	-	-	2.8	2017-04-05	10.1038/nature22035
5UNG	A	Peptide	Angiotensin	AT₂	Homo sapiens	PubChem 15780052	-	-	2.8	2017-04-05	10.1038/nature22035
5UNH	A	Peptide	Angiotensin	AT₂	Homo sapiens	PubChem 126456406	-	-	2.9	2017-04-05	10.1038/nature22035
5XJM	A	Peptide	Angiotensin	AT₂	Homo sapiens	(Sar1,Ile8)-Angiotensin II	-	-	3.2	2018-07-11	10.1038/s41594-018-0079-8
6JOD	A	Peptide	Angiotensin	AT₂	Homo sapiens	Angiotensin II	-	-	3.2	2020-01-15	10.1016/j.str.2019.12.003
7C6A	A	Peptide	Angiotensin	AT₂	Homo sapiens	(Sar1,Ile8)-Angiotensin II	-	-	3.4	2020-07-29	10.1038/s41598-020-68355-x
7JNI	A	Peptide	Angiotensin	AT₂	Homo sapiens	Olodanrigan	-	-	3	2022-02-09	10.1073/pnas.2116289119
8H0P	A	Peptide	Bombesin	BB₁	Homo sapiens	NMB30	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.15	2023-08-09	10.1038/s41422-022-00743-6
7W3Z	A	Peptide	Bombesin	BB₂	Homo sapiens	Gastrin Releasing Peptide	-	chim(NtGi1L-Gq)/&β;1/&γ;2	3	2023-02-22	10.1073/pnas.2216230120
7W40	A	Peptide	Bombesin	BB₂	Homo sapiens	Bombesin	-	chim(NtGi1L-Gq)/&β;1/&γ;2	3	2023-02-22	10.1073/pnas.2216230120
7W41	A	Peptide	Bombesin	BB₂	Homo sapiens	PD176252	-	-	2.95	2023-02-22	10.1073/pnas.2216230120
8H0Q	A	Peptide	Bombesin	BB₂	Homo sapiens	Gastrin Releasing Peptide	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.3	2023-08-09	10.1038/s41422-022-00743-6
2VT4	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	2.7	2008-06-24	10.1038/nature07101
2Y00	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	-	2.5	2011-01-12	10.1038/nature09746
2Y01	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	-	2.6	2011-03-30	10.1038/nature09746
2Y02	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Carmoterol	-	-	2.6	2011-01-12	10.1038/nature09746
2Y03	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	-	2.85	2011-01-12	10.1038/nature09746
2Y04	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Salbutamol	-	-	3.05	2011-01-12	10.1038/nature09746
2YCW	A	Amine	Adrenergic	β₁	Meleagris gallopavo	(S)-Carazolol	-	-	3	2011-06-01	10.1073/pnas.1100185108
2YCX	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	3.25	2011-06-01	10.1073/pnas.1100185108
2YCY	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	3.15	2011-06-08	10.1073/pnas.1100185108
2YCZ	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Iodocyanopindolol	-	-	3.65	2011-06-01	10.1073/pnas.1100185108
3ZPQ	A	Amine	Adrenergic	β₁	Meleagris gallopavo	4-(piperazin-1- yl)-1H-indole	Na	-	2.8	2013-04-03	10.1021/jm400140q
3ZPR	A	Amine	Adrenergic	β₁	Meleagris gallopavo	4-methyl-2-(piperazin-1-yl)	Na	-	2.7	2013-04-03	10.1021/jm400140q
4AMI	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Bucindolol	-	-	3.2	2012-05-23	10.1016/j.str.2012.03.014
4AMJ	A	Amine	Adrenergic	β₁	Meleagris gallopavo	(S)-Carvedilol	-	-	2.3	2012-05-23	10.1016/j.str.2012.03.014
4BVN	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	Na	-	2.1	2014-04-02	10.1371/journal.pone.0092727
4GPO	A	Amine	Adrenergic	β₁	Meleagris gallopavo	-	-	-	3.5	2013-02-27	10.1038/nsmb.2504
5A8E	A	Amine	Adrenergic	β₁	Meleagris gallopavo	7-Methylcyanopindolol	Na	-	2.4	2015-09-30	10.1124/mol.115.101030
5F8U	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	3.35	2015-12-23	10.1038/nsmb.3130
6H7J	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	-	2.8	2018-10-17	10.1126/science.aau5595
6H7L	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	-	2.7	2018-10-17	10.1126/science.aau5595
6H7M	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Salbutamol	-	-	2.76	2018-10-17	10.1126/science.aau5595
6H7N	A	Amine	Adrenergic	β₁	Meleagris gallopavo	(S)-Xamoterol	-	-	2.5	2018-10-17	10.1101/436212
6H7O	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	-	2.8	2018-10-17	10.1126/science.aau5595
6IBL	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Arformoterol	-	-	2.7	2019-01-09	10.1038/s41586-020-2419-1
6TKO	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Arformoterol	-	Arrestin2	3.3	2020-06-17	10.1038/s41586-020-2419-1
7BTS	A	Amine	Adrenergic	β₁	Homo sapiens	L-Epinephrine	-	-	3.13	2020-12-02	10.1038/s41422-020-00424-2
7BU6	A	Amine	Adrenergic	β₁	Homo sapiens	L-Norepinephrine	-	-	2.7	2020-12-02	10.1038/s41422-020-00424-2
7BU7	A	Amine	Adrenergic	β₁	Homo sapiens	BI167107	-	-	2.6	2020-12-02	10.1038/s41422-020-00424-2
7BVQ	A	Amine	Adrenergic	β₁	Homo sapiens	(S)-Carazolol	-	-	2.5	2020-12-02	10.1038/s41422-020-00424-2
7JJO	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	Gs/&β;1/&γ;2	2.6	2020-09-02	10.1016/j.molcel.2020.08.001
7S0F	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	Gi1/&β;1/&γ;2	2.96	2021-11-17	10.1038/s41594-021-00679-2
7S0G	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Isoprenaline	-	chim(Gi1-CtGs)/&β;1/&γ;2	3.86	2021-11-17	10.1038/s41594-021-00679-2
8DCR	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Dobutamine	-	Gs/&β;1/&γ;2	2.6	2022-07-27	10.1038/s41467-022-31823-1
8DCS	A	Amine	Adrenergic	β₁	Meleagris gallopavo	Cyanopindolol	-	Gs/&β;1/&γ;2	2.5	2022-07-27	10.1038/s41467-022-31823-1
2R4R	A	Amine	Adrenergic	β₂	Homo sapiens	-	-	-	3.4	2007-11-06	10.1038/nature06325
2R4S	A	Amine	Adrenergic	β₂	Homo sapiens	-	-	-	3.4	2007-11-06	10.1038/nature06325
2RH1	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	2.4	2007-10-30	10.1126/science.1150577
3D4S	A	Amine	Adrenergic	β₂	Homo sapiens	Timolol Maleate	-	-	2.8	2008-06-17	10.1016/j.str.2008.05.001
3KJ6	A	Amine	Adrenergic	β₂	Homo sapiens	-	-	-	3.4	2010-02-16	10.1038/nature08650
3NY8	A	Amine	Adrenergic	β₂	Homo sapiens	ICI 118-551	-	-	2.84	2010-08-11	10.1021/ja105108q
3NY9	A	Amine	Adrenergic	β₂	Homo sapiens	PubChem 913103	-	-	2.84	2010-08-11	10.1021/ja105108q
3NYA	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	-	-	3.16	2010-08-11	10.1021/ja105108q
3P0G	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	-	3.5	2011-01-19	10.1038/nature09648
3PDS	A	Amine	Adrenergic	β₂	Homo sapiens	Hydroxybenzylisoproterenol	-	-	3.5	2011-01-12	10.1038/nature09665
3SN6	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	Gs/&β;1/&γ;2	3.2	2011-07-20	10.1038/nature10361
4GBR	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.99	2012-10-24	10.1371/journal.pone.0046039
4LDE	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	-	2.79	2013-09-25	10.1038/nature12572
4LDL	A	Amine	Adrenergic	β₂	Homo sapiens	Hydroxybenzylisoproterenol	-	-	3.1	2013-09-25	10.1038/nature12572
4LDO	A	Amine	Adrenergic	β₂	Homo sapiens	L-Epinephrine	-	-	3.2	2013-09-25	10.1038/nature12572
4QKX	A	Amine	Adrenergic	β₂	Homo sapiens	PubChem 76210628	-	-	3.3	2014-07-23	10.1073/pnas.1410415111
5D5A	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	2.48	2016-01-13	10.1107/S2059798315021683
5D5B	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.8	2016-01-13	10.1107/S2059798315021683
5D6L	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.2	2016-08-17	10.1038/nprot.2017.057
5JQH	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.2	2016-07-13	10.1038/nature18636
5X7D	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	PubChem 129318963	-	2.7	2017-08-16	10.1038/nature23652
6E67	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	Gs (fused)	3.7	2019-06-05	10.1016/j.cell.2019.04.021
6MXT	A	Amine	Adrenergic	β₂	Homo sapiens	Salmeterol	-	-	2.96	2018-11-14	10.1038/s41589-018-0145-x
6N48	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	PubChem 138454256	-	3.2	2019-06-26	10.1126/science.aaw8981
6NI3	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	Gs/&β;1/&γ;2	3.8	2019-11-20	10.1038/s41594-019-0330-y
6OBA	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	GTPL11074	-	3.1	2020-03-25	10.1038/s41589-020-0549-2
6PRZ	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	-	-	2.8	2019-11-13	10.1107/S2052252519013137
6PS0	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.4	2019-11-13	10.1107/S2052252519013137
6PS1	A	Amine	Adrenergic	β₂	Homo sapiens	Timolol	-	-	3.2	2019-11-13	10.1107/S2052252519013137
6PS2	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	-	-	2.4	2019-11-13	10.1107/S2052252519013137
6PS3	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carvedilol	-	-	2.5	2019-11-13	10.1107/S2052252519013137
6PS4	A	Amine	Adrenergic	β₂	Homo sapiens	ICI 118-551	-	-	2.6	2019-11-13	10.1107/S2052252519013137
6PS5	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Propranolol	-	-	2.9	2019-11-13	10.1107/S2052252519013137
6PS6	A	Amine	Adrenergic	β₂	Homo sapiens	Timolol	-	-	2.7	2019-11-13	10.1107/S2052252519013137
7BZ2	A	Amine	Adrenergic	β₂	Homo sapiens	Arformoterol	-	Gs/&β;1/&γ;2	3.82	2020-08-05	10.1038/s41421-020-0176-9
7DHI	A	Amine	Adrenergic	β₂	Homo sapiens	Salbutamol	-	Gs/&β;1/&γ;2	3.26	2020-12-16	10.1093/nsr/nwaa284
7DHR	A	Amine	Adrenergic	β₂	Homo sapiens	Isoprenaline	-	Gs/&β;1/&γ;2	3.8	2020-12-16	10.1093/nsr/nwaa284
7XKA	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.1	2023-04-26	10.1038/s41467-023-37808-y
8GDZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GE1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GE3	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8GE4	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8GE6	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GE7	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GE8	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GE9	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GEA	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GEB	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
8GEC	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GED	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GEE	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.7	2024-03-06	10.1038/s41586-024-07153-1
8GEF	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.8	2024-03-06	10.1038/s41586-024-07153-1
8GEG	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.8	2024-03-06	10.1038/s41586-024-07153-1
8GEH	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	4	2024-03-06	10.1038/s41586-024-07153-1
8GEI	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	4.1	2024-03-06	10.1038/s41586-024-07153-1
8GEJ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	4.2	2024-03-06	10.1038/s41586-024-07153-1
8GFV	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.1	2024-03-06	10.1038/s41586-024-07153-1
8GFW	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
8GFX	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
8GFY	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
8GFZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
8GG0	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	2.9	2024-03-06	10.1038/s41586-024-07153-1
8GG1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
8GG2	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
8GG3	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.1	2024-03-06	10.1038/s41586-024-07153-1
8GG4	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.2	2024-03-06	10.1038/s41586-024-07153-1
8GG5	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.2	2024-03-06	10.1038/s41586-024-07153-1
8GG6	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8GG7	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8GG8	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8GG9	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GGA	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGB	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGC	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GGE	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGF	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
8GGI	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGJ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGK	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.3	2024-03-06	10.1038/s41586-024-07153-1
8GGL	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
8GGM	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
8GGN	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.3	2024-03-06	10.1038/s41586-024-07153-1
8GGO	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
8GGP	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
8GGQ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GGR	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GGS	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGT	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGU	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.4	2024-03-06	10.1038/s41586-024-07153-1
8GGV	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
8GGW	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.6	2024-03-06	10.1038/s41586-024-07153-1
8GGX	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.6	2024-03-06	10.1038/s41586-024-07153-1
8GGY	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.9	2024-03-06	10.1038/s41586-024-07153-1
8GGZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.9	2024-03-06	10.1038/s41586-024-07153-1
8GH0	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	4	2024-03-06	10.1038/s41586-024-07153-1
8GH1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	4.1	2024-03-06	10.1038/s41586-024-07153-1
8JJ8	A	Amine	Adrenergic	β₂	Homo sapiens	Formoterol	-	-	3.2	2023-09-06	10.1038/s41589-023-01389-0
8JJL	A	Amine	Adrenergic	β₂	Homo sapiens	Olodaterol	-	-	3.2	2023-09-06	10.1038/s41589-023-01389-0
8JJO	A	Amine	Adrenergic	β₂	Homo sapiens	Alprenolol	-	-	3.4	2023-09-06	10.1038/s41589-023-01389-0
8UNL	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8UNM	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8UNN	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8UNO	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8UNP	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8UNQ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8UNR	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8UNS	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8UNT	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8UNU	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8UNV	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
8UNW	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
8UNX	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
8UNY	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
8UNZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.8	2024-03-06	10.1038/s41586-024-07153-1
8UO0	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8UO1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP; Mg	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
8UO2	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
8UO3	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP; Mg	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
8UO4	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP; Mg	Gs/&β;1/&γ;2	4	2024-03-06	10.1038/s41586-024-07153-1
7DH5	A	Amine	Adrenergic	β₃	Canis lupus familiaris	Mirabegron	-	Gs/&β;1/&γ;2	3.16	2021-08-04	10.1016/j.molcel.2021.06.024
7XJH	A	Amine	Adrenergic	β₃	Canis lupus familiaris	Isoproterenol	-	Gs/&β;1/&γ;2	3.3	2022-05-04	10.1016/j.molcel.2021.06.024
7XJI	A	Amine	Adrenergic	β₃	Canis lupus familiaris	Solabegron	-	Gs/&β;1/&γ;2	3.9	2022-05-04	10.1016/j.bbrc.2022.04.065
7JHJ	A	Other	Unclassified	BILF1	Human gammaherpesvirus 4	-	-	Gi1/&β;1/&γ;2	3.2	2021-07-07	10.1016/j.immuni.2021.06.001
7EIB	A	Peptide	Bradykinin	BK₁	Homo sapiens	Des-Arg10-Kallidin	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3	2021-10-13	10.1038/s41594-021-00645-y
7F2O	A	Peptide	Bradykinin	BK₂	Homo sapiens	Bradykinin	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.9	2021-10-13	10.1038/s41594-021-00645-y
7F6H	A	Peptide	Bradykinin	BK₂	Homo sapiens	Bradykinin	-	Gq/&β;1/&γ;2	2.9	2022-01-05	10.1038/s41467-022-28399-1
7F6I	A	Peptide	Bradykinin	BK₂	Homo sapiens	Kallidin	-	Gq/&β;1/&γ;2	2.8	2022-01-05	10.1038/s41467-022-28399-1
5X33	A	Lipid	Leukotriene	BLT₁	Cavia porcellus	BIIL260	-	-	3.7	2018-01-03	10.1038/nchembio.2547
7K15	A	Lipid	Leukotriene	BLT₁	Homo sapiens	MKD046	Na	-	2.88	2021-02-17	10.1038/s41467-021-23149-1
7VKT	A	Lipid	Leukotriene	BLT₁	Homo sapiens	LTB4	-	Gi1/&β;1/&γ;2	2.9	2022-03-09	10.1038/s41467-022-28820-9
8HK2	A	Peptide	Complement peptide	C3a_B	Homo sapiens	C3a anaphylatoxin	-	Gi1/&β;1/&γ;2	2.9	2023-05-10	10.1038/s41589-023-01339-w
8HK3	A	Peptide	Complement peptide	C3a_B	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.2	2023-05-10	10.1038/s41589-023-01339-w
8I95	A	Peptide	Complement peptide	C3a_B	Homo sapiens	EP54	-	Go/&β;1/&γ;2	2.88	2023-10-18	10.1016/j.cell.2023.09.020
8I97	A	Peptide	Complement peptide	C3a_B	Homo sapiens	-	-	Go/&β;1/&γ;2	3.1	2023-10-18	10.1016/j.cell.2023.09.020
8I9A	A	Peptide	Complement peptide	C3a_B	Homo sapiens	EP54	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.57	2023-10-18	10.1016/j.cell.2023.09.020
8I9L	A	Peptide	Complement peptide	C3a_B	Homo sapiens	C3a anaphylatoxin	-	Go/&β;1/&γ;2	3.18	2023-10-18	10.1016/j.cell.2023.09.020
8I9S	A	Peptide	Complement peptide	C3a_B	Homo sapiens	-	-	Go/&β;1/&γ;2	3.26	2023-10-18	10.1016/j.cell.2023.09.020
8IA8	A	Peptide	Complement peptide	C3a_B	Homo sapiens	E7 peptide	-	Gi1/&β;1/&γ;2	2.86	2023-05-24	To be published
8J6D	A	Peptide	Complement peptide	C3a_B	Homo sapiens	EP141	-	Go/&β;1/&γ;2	3.1	2023-10-18	10.1016/j.cell.2023.09.020
5O9H	A	Peptide	Complement peptide	C5a₁	Homo sapiens	-	NDT9513727	-	2.7	2018-01-10	10.1038/nature25025
6C1Q	A	Peptide	Complement peptide	C5a₁	Homo sapiens	PMX53	NDT9513727	-	2.9	2018-05-30	10.1038/s41594-018-0067-z
6C1R	A	Peptide	Complement peptide	C5a₁	Homo sapiens	PMX53	Avacopan; Na	-	2.2	2018-05-30	10.1038/s41594-018-0067-z
7Y64	A	Peptide	Complement peptide	C5a₁	Homo sapiens	C5a anaphylatoxin	-	Gi1/&β;1/&γ;2	2.9	2023-03-01	10.1038/s41422-023-00779-2
7Y65	A	Peptide	Complement peptide	C5a₁	Homo sapiens	C5a peptide	-	Gi1/&β;1/&γ;2	3.2	2023-03-01	10.1038/s41422-023-00779-2
7Y66	A	Peptide	Complement peptide	C5a₁	Homo sapiens	BM213	-	Gi1/&β;1/&γ;2	2.9	2023-03-01	10.1038/s41422-023-00779-2
7Y67	A	Peptide	Complement peptide	C5a₁	Homo sapiens	C089 peptide	-	Gi1/&β;1/&γ;2	2.8	2023-03-01	10.1038/s41422-023-00779-2
8HK5	A	Peptide	Complement peptide	C5a₁	Homo sapiens	Complement C5	-	Gi1/&β;1/&γ;2	3	2023-05-10	10.1038/s41589-023-01339-w
8HPT	A	Peptide	Complement peptide	C5a₁	Mus musculus	C5a anaphylatoxin C-terminal peptide	-	Go/&β;1/&γ;2	3.39	2023-10-18	10.1016/j.cell.2023.09.020
8HQC	A	Peptide	Complement peptide	C5a₁	Mus musculus	C5a anaphylatoxin	-	Go/&β;1/&γ;2	3.89	2023-10-18	10.1016/j.cell.2023.09.020
8IA2	A	Peptide	Complement peptide	C5a₁	Homo sapiens	C5a anaphylatoxin	-	Go/&β;1/&γ;2	3.21	2023-10-18	10.1016/j.cell.2023.09.020
8JZZ	A	Peptide	Complement peptide	C5a₁	Homo sapiens	C5a-desArg	-	Go/&β;1/&γ;2	3.31	2023-10-18	10.1016/j.cell.2023.09.020
7DD5	C	Ion	Calcium-sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan; NPS-2143	-	3.2	2021-06-16	10.1126/sciadv.abg1483
7DD6	C	Ion	Calcium-sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan	-	3.2	2021-06-16	10.1126/sciadv.abg1483
7DD7	C	Ion	Calcium-sensing	CaS	Gallus gallus	Ca	Ca; Ca; Tryptophan; Evocalcet	-	3.2	2021-06-16	10.1126/sciadv.abg1483
7DTT	C	Ion	Calcium-sensing	CaS	Homo sapiens	Ca	Ca	-	3.8	2021-03-10	10.1038/s41422-021-00474-0
7DTU	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Tryptophan	-	4.4	2021-03-10	10.1038/s41422-021-00474-0
7DTV	C	Ion	Calcium-sensing	CaS	Homo sapiens	Ca	Ca; Tryptophan	-	3.5	2021-03-10	10.1038/s41422-021-00474-0
7DTW	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	-	-	4.5	2021-03-10	10.1038/s41422-021-00474-0
7E6T	C	Ion	Calcium-sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; PO4	-	3	2021-09-22	10.7554/eLife.68578
7E6U	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	-	-	6	2021-09-22	10.7554/eLife.68578
7M3E	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; NPS-2143; PO4	-	3.2	2021-06-30	10.1038/s41586-021-03691-0
7M3F	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4	-	2.8	2021-06-30	10.1038/s41586-021-03691-0
7M3G	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	-	2.5	2021-06-30	10.1038/s41586-021-03691-0
7M3J	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	NPS-2143; PO4	-	4.1	2021-06-30	10.1038/s41586-021-03691-0
7SIL	C	Ion	Calcium-sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	-	2.7	2022-01-19	10.1073/pnas.2115849118
7SIM	C	Ion	Calcium-sensing	CaS	Homo sapiens	Ca	Ca; Ca; Cyclomethyltryptophan; PO4	-	2.7	2022-01-19	10.1073/pnas.2115849118
7SIN	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	NPS-2143	-	5.9	2022-01-19	10.1073/pnas.2115849118
8SZF	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	-	2.8	2024-02-07	10.1038/s41586-024-07055-2
8SZG	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	chim(NtGi1-Gq)/&β;1/&γ;2	3.6	2024-02-07	10.1038/s41586-024-07055-2
8SZH	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	Gi1/&β;1/&γ;2	3.1	2024-02-07	10.1038/s41586-024-07055-2
8SZI	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	Gi3/&β;1/&γ;2	3.5	2024-02-07	10.1038/s41586-024-07055-2
8WPG	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca	-	2.7	2023-11-22	10.1038/s41422-023-00892-2
8WPU	C	Ion	Calcium-sensing	CaS	Homo sapiens	-	Tryptophan; Cinacalcet; PO4; Ca	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.1	2023-11-22	10.1038/s41422-023-00892-2
9AXF	C	Ion	Calcium-sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.5	2024-04-17	10.1038/s41586-024-07331-1
9AYF	C	Ion	Calcium-sensing	CaS	Homo sapiens	Ca	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	Gi1/&β;1/&γ;2	3.6	2024-04-17	10.1038/s41586-024-07331-1
5TGZ	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM6538	-	-	2.8	2016-11-02	10.1016/j.cell.2016.10.004
5U09	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Taranabant	-	-	2.6	2016-12-07	10.1038/nature20613
5XR8	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM841	-	-	2.95	2017-07-12	10.1038/nature23272
5XRA	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM11542	-	-	2.8	2017-07-12	10.1038/nature23272
6KPG	A	Lipid	Cannabinoid	CB₁	Homo sapiens	AM841	-	Gi1/&β;1/&γ;2	3	2020-02-12	10.1016/j.cell.2020.01.008
6KQI	A	Lipid	Cannabinoid	CB₁	Homo sapiens	PubMed 104895	ORG27569	-	3.25	2019-10-23	10.1038/s41589-019-0387-2
6N4B	A	Lipid	Cannabinoid	CB₁	Homo sapiens	MDMB-Fubinaca	-	Gi1/&β;1/&γ;2	3	2019-01-30	10.1016/j.cell.2018.11.040
7FEE	A	Lipid	Cannabinoid	CB₁	Homo sapiens	PubMed 104895	ZCZ011	-	2.7	2022-06-15	10.1038/s41589-022-01038-y
7V3Z	A	Lipid	Cannabinoid	CB₁	Homo sapiens	PubMed 104895	-	-	3.29	2021-11-24	10.1021/jacs.1c06847
7WV9	A	Lipid	Cannabinoid	CB₁	Homo sapiens	PubMed 104895	ZCZ011	Gi2/&β;1/&γ;2	3.36	2022-06-15	10.1038/s41589-022-01038-y
8GAG	A	Lipid	Cannabinoid	CB₁	Homo sapiens	YVF	-	Gi1/&β;1/&γ;2	3.3	2024-02-28	To be published
8GHV	A	Lipid	Cannabinoid	CB₁	Homo sapiens	PubChem 145964903	-	Gi1/&β;1/&γ;2	2.8	2023-05-24	10.1038/s41467-023-37864-4
8K8J	A	Lipid	Cannabinoid	CB₁	Homo sapiens	Fenofibrate	-	chim(Gs-CtGq)/&β;1/&γ;2	2.88	2024-02-14	10.1002/advs.202306311
8WRZ	A	Lipid	Cannabinoid	CB₁	Homo sapiens	8D0	-	Arrestin1	3.6	2024-02-28	10.1093/procel/pwad055
8WU1	A	Lipid	Cannabinoid	CB₁	Homo sapiens	KCA	-	Arrestin1	3.2	2024-03-20	To be published
5ZTY	A	Lipid	Cannabinoid	CB₂	Homo sapiens	AM10257	-	-	2.8	2019-01-30	10.1016/j.cell.2018.12.011
6KPC	A	Lipid	Cannabinoid	CB₂	Homo sapiens	PubChem 145915889	-	-	3.2	2020-02-12	10.1016/j.cell.2020.01.008
6KPF	A	Lipid	Cannabinoid	CB₂	Homo sapiens	PubChem 145915889	-	Gi1/&β;1/&γ;2	2.9	2020-02-12	10.1016/j.cell.2020.01.008
6PT0	A	Lipid	Cannabinoid	CB₂	Homo sapiens	WIN 55212-2	-	Gi1/&β;1/&γ;2	3.2	2020-02-12	10.1016/j.cell.2020.01.007
8GUQ	A	Lipid	Cannabinoid	CB₂	Homo sapiens	Olorinab	-	Gi1/&β;1/&γ;2	3.08	2023-05-10	10.1038/s41467-023-37112-9
8GUR	A	Lipid	Cannabinoid	CB₂	Homo sapiens	PubChem 104895	-	Gi1/&β;1/&γ;2	2.84	2023-05-10	10.1038/s41467-023-37112-9
8GUS	A	Lipid	Cannabinoid	CB₂	Homo sapiens	HU-308	-	Gi1/&β;1/&γ;2	2.97	2023-05-10	10.1038/s41467-023-37112-9
8GUT	A	Lipid	Cannabinoid	CB₂	Homo sapiens	LEI-102	-	Gi1/&β;1/&γ;2	2.98	2023-05-10	10.1038/s41467-023-37112-9
7EZH	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	Gi1/&β;1/&γ;2	3.2	2021-08-25	10.1038/s41589-021-00841-3
7EZK	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2021-08-25	10.1038/s41589-021-00841-3
7EZM	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGsL-Gq)/&β;1/&γ;2	2.9	2021-08-25	10.1038/s41589-021-00841-3
7F8U	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Lintitript	-	-	2.8	2021-10-13	10.1038/s41589-021-00866-8
7F8X	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	NN9056	-	-	3	2021-12-29	10.1038/s41589-021-00866-8
7F8Y	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Devazepide	-	-	2.5	2021-10-13	10.1038/s41589-021-00866-8
7MBX	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	Gs/&β;1/&γ;1	1.95	2021-05-26	10.1371/journal.pbio.3001295
7MBY	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2	2.44	2021-05-26	10.1371/journal.pbio.3001295
7XOU	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	Cholecystokinin-8	-	Gs/&β;1/&γ;2	3.2	2022-07-20	10.1038/s41421-022-00420-3
7XOV	A	Peptide	Cholecystokinin	CCK_A	Homo sapiens	SR146131	-	Gs/&β;1/&γ;2	3	2022-07-20	10.1038/s41421-022-00420-3
7F8V	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin-17	-	Gi2/&β;1/&γ;2	3.3	2021-10-13	10.1038/s41589-021-00866-8
7F8W	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin-17	-	chim(NtGsL-Gq)/&β;1/&γ;2	3.1	2021-10-13	10.1038/s41589-021-00866-8
7XOW	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Gastrin	-	Gq/&β;1/&γ;2	3.1	2022-07-20	10.1038/s41421-022-00420-3
7XOX	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Cholecystokinin-8	-	Gq/&β;1/&γ;2	3.1	2022-07-20	10.1038/s41421-022-00420-3
8IA7	A	Peptide	Cholecystokinin	CCK_B	Homo sapiens	Cholecystokinin-8	-	chim(NtGi1L-Gq)/&β;1/&γ;2	3.1	2023-12-06	10.1038/s41421-022-00420-3
7VL8	A	Protein	Chemokine	CCR1	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.9	2022-03-23	10.1038/s41589-021-00918-z
7VL9	A	Protein	Chemokine	CCR1	Homo sapiens	CCL15(26-92)	-	Gi1/&β;1/&γ;2	2.6	2022-03-23	10.1038/s41589-021-00918-z
7VLA	A	Protein	Chemokine	CCR1	Homo sapiens	CCL15(27-92)	-	Gi1/&β;1/&γ;2	2.7	2022-03-23	10.1038/s41589-021-00918-z
5T1A	A	Protein	Chemokine	CCR2	Homo sapiens	-	PubChem 68764898; PubChem 12093170	-	2.81	2016-12-14	10.1038/nature20605
6GPS	A	Protein	Chemokine	CCR2	Homo sapiens	-	MK0812	-	3.3	2019-01-02	10.1016/j.str.2018.10.027
6GPX	A	Protein	Chemokine	CCR2	Homo sapiens	-	MK0812	-	2.7	2019-01-02	10.1016/j.str.2018.10.027
7XA3	A	Protein	Chemokine	CCR2	Homo sapiens	CCL2	-	Gi1/&β;1/&γ;2	2.9	2022-08-24	10.1038/s41421-022-00403-4
7X9Y	A	Protein	Chemokine	CCR3	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.1	2022-08-24	10.1038/s41421-022-00403-4
4MBS	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.71	2013-09-11	10.1126/science.1241475
5UIW	A	Protein	Chemokine	CCR5	Homo sapiens	5P7-CCL5	-	-	2.2	2017-06-28	10.1016/j.immuni.2017.05.002
6AKX	A	Protein	Chemokine	CCR5	Homo sapiens	-	A4R	-	2.8	2018-10-24	10.1021/acs.jmedchem.8b01077
6AKY	A	Protein	Chemokine	CCR5	Homo sapiens	-	Maraviroc	-	2.8	2018-10-24	10.1021/acs.jmedchem.8b01077
6MEO	A	Protein	Chemokine	CCR5	Homo sapiens	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	-	-	3.9	2018-12-12	10.1038/s41586-018-0804-9
6MET	A	Protein	Chemokine	CCR5	Homo sapiens	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	-	-	4.5	2018-12-12	10.1038/s41586-018-0804-9
7F1Q	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-	Gi1/&β;1/&γ;2	2.9	2021-07-14	10.1038/s41467-021-24438-5
7F1R	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3	2021-07-14	10.1038/s41467-021-24438-5
7F1S	A	Protein	Chemokine	CCR5	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.8	2021-07-14	10.1038/s41467-021-24438-5
7F1T	A	Protein	Chemokine	CCR5	Homo sapiens	MIP-1a	-	-	2.6	2021-07-14	10.1038/s41467-021-24438-5
7O7F	A	Protein	Chemokine	CCR5	Homo sapiens	(6P4)CCL5	-	Gi1/&β;1/&γ;1	3.15	2021-06-30	10.1126/sciadv.abg8685
6WWZ	A	Protein	Chemokine	CCR6	Homo sapiens	CCL20	-	Go/&β;1/&γ;2	3.34	2020-06-24	10.1038/s41467-020-16820-6
6QZH	A	Protein	Chemokine	CCR7	Homo sapiens	-	HY-133073; Na	-	2.1	2019-09-04	10.1016/j.cell.2019.07.028
8KFX	A	Protein	Chemokine	CCR8	Homo sapiens	LMD-009	-	Gi1/&β;1/&γ;2	2.96	2024-02-07	10.1126/sciadv.adj7500
8KFY	A	Protein	Chemokine	CCR8	Homo sapiens	ZK-756326	-	Gi1/&β;1/&γ;2	3.06	2024-02-07	10.1126/sciadv.adj7500
8KFZ	A	Protein	Chemokine	CCR8	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.3	2024-02-07	10.1126/sciadv.adj7500
8TLM	A	Protein	Chemokine	CCR8	Homo sapiens	Anti-murine CCR8 antibody	-	-	3.9	2023-12-20	10.1038/s41467-023-43601-8
8U1U	A	Protein	Chemokine	CCR8	Homo sapiens	CCL1	-	Gi1/&β;1/&γ;2	3.1	2023-12-20	10.1038/s41467-023-43601-8
5LWE	A	Protein	Chemokine	CCR9	Homo sapiens	-	Vercirnon	-	2.8	2016-12-07	10.1038/nature20606
7YKD	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-	Gi1/&β;1/&γ;2	2.81	2023-04-19	10.1073/pnas.2214324120
8SG1	A	Protein	Chemerin	CML1	Homo sapiens	Chemerin-9	-	Gi1/&β;1/&γ;2	2.94	2023-11-01	10.1371/journal.pbio.3002188
4K5Y	B1	Peptide	Corticotropin Releasing Factor	CRF₁	Homo sapiens	-	CP-376395	-	2.98	2013-07-17	10.1038/nature12357
4Z9G	B1	Peptide	Corticotropin Releasing Factor	CRF₁	Homo sapiens	-	CP-376395	-	3.18	2016-06-29	10.2174/1874467210666170110114727
6P9X	B1	Peptide	Corticotropin Releasing Factor	CRF₁	Homo sapiens	Corticoliberin	-	Gs/&β;1/&γ;2	2.91	2020-02-05	10.1016/j.molcel.2020.01.012
6PB0	B1	Peptide	Corticotropin Releasing Factor	CRF₁	Homo sapiens	Urocortin	-	chim(NtGi1-Gs)/&β;1/&γ;2	3	2020-02-12	10.1016/j.molcel.2020.01.013
8GTG	B1	Peptide	Corticotropin Releasing Factor	CRF₁	Homo sapiens	-	BMK-I152	-	2.75	2023-09-13	10.1038/s12276-023-01082-1
8GTI	B1	Peptide	Corticotropin Releasing Factor	CRF₁	Homo sapiens	-	BMK-C205	-	2.2	2023-09-13	10.1038/s12276-023-01082-1
8GTM	B1	Peptide	Corticotropin Releasing Factor	CRF₁	Homo sapiens	-	BMK-C203	-	2.6	2023-09-13	10.1038/s12276-023-01082-1
6PB1	B1	Peptide	Corticotropin Releasing Factor	CRF₂	Homo sapiens	Urocortin	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.8	2020-02-12	10.1016/j.molcel.2020.01.013
7TRY	B1	Peptide	Corticotropin Releasing Factor	CRF₂	Homo sapiens	Urocortin	-	chim(NtGi1-G11)/&β;1/&γ;2	3.7	2022-11-09	10.1038/s41467-022-33851-3
7TS0	B1	Peptide	Corticotropin Releasing Factor	CRF₂	Homo sapiens	Urocortin	-	chim(NtGi1L-Go)/&β;1/&γ;2	2.8	2022-11-09	10.1038/s41467-022-33851-3
5UZ7	B1	Peptide	Calcitonin	CT	Homo sapiens	-	-	Gs/&β;1/&γ;2	4.1	2017-05-03	10.1038/nature22327
6NIY	B1	Peptide	Calcitonin	CT	Homo sapiens	Adrenomedullin	-	Gs/&β;1/&γ;2	3.34	2019-01-23	10.1021/acsptsci.8b00056
7TYI	B1	Peptide	Calcitonin	CT	Homo sapiens	Amylin	-	Gs/&β;1/&γ;2	3.3	2022-03-30	10.1126/science.abm9609
7TYL	B1	Peptide	Calcitonin	CT	Homo sapiens	Amylin	-	Gs/&β;1/&γ;2	3.3	2022-03-23	10.1126/science.abm9609
7TYN	B1	Peptide	Calcitonin	CT	Homo sapiens	Calcitonin-1	-	Gs/&β;1/&γ;2	2.6	2022-03-30	10.1126/science.abm9609
7TYO	B1	Peptide	Calcitonin	CT	Homo sapiens	Calcitonin	-	Gs/&β;1/&γ;2	2.7	2022-03-23	10.1126/science.abm9609
8F0J	B1	Peptide	Calcitonin	CT	Homo sapiens	Pramlintide analogue san45	-	Gs/&β;1/&γ;2	2	2023-08-02	10.1038/s41589-023-01393-4
9AUC	B1	Peptide	Calcitonin	CT	Homo sapiens	Calcitonin gene-related peptide-1	-	Gs/&β;1/&γ;2; RAMP1	2.4	2024-04-24	10.1021/acs.biochem.4c00114
7TYF	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Amylin	-	Gs/&β;1/&γ;2; RAMP1	2.2	2022-03-23	10.1126/science.abm9609
7TYW	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin-1	-	Gs/&β;1/&γ;2; RAMP1	3	2022-03-23	10.1126/science.abm9609
7TYH	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-	Gs/&β;1/&γ;2; RAMP2	3.3	2022-03-23	10.1126/science.abm9609
7TYX	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Amylin	-	Gs/&β;1/&γ;2; RAMP2	2.55	2022-03-30	10.1126/science.abm9609
7TYY	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-	Gs/&β;1/&γ;2; RAMP2	3	2022-03-23	10.1126/science.abm9609
7TZF	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Amylin	-	Gs/&β;1/&γ;2; RAMP3	2.4	2022-03-23	10.1126/science.abm9609
8F0K	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide analogue san385	-	Gs/&β;1/&γ;2; RAMP3	1.9	2023-08-02	10.1038/s41589-023-01393-4
8F2A	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide analogue san385	-	Gs/&β;1/&γ;2; RAMP3	2.2	2023-08-02	10.1038/s41589-023-01393-4
8F2B	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide analogue san45	-	Gs/&β;1/&γ;2; RAMP3	2	2023-08-02	10.1038/s41589-023-01393-4
6E3Y	B1	Peptide	Calcitonin	CT Like	Homo sapiens	Calcitonin gene-related peptide-1	-	Gs/&β;1/&γ;2; RAMP1	3.3	2018-09-19	10.1038/s41586-018-0535-y
7KNT	B1	Peptide	Calcitonin	CT Like	Homo sapiens	-	-	RAMP1	3.15	2021-02-24	10.1126/science.abf7258
7KNU	B1	Peptide	Calcitonin	CT Like	Homo sapiens	Calcitonin gene-related peptide-1	-	RAMP1	3.49	2021-02-24	10.1126/science.abf7258
6UUN	B1	Peptide	Calcitonin	CT Like (AM1)	Homo sapiens	Adrenomedullin	-	Gs/&β;1/&γ;2; RAMP2	3	2020-03-25	10.1021/acsptsci.9b00080
6UUS	B1	Peptide	Calcitonin	CT Like (AM2)	Homo sapiens	Adrenomedullin	-	Gs/&β;1/&γ;2; RAMP3	2.4	2020-04-01	10.1021/acsptsci.9b00080
6UVA	B1	Peptide	Calcitonin	CT Like (AM2)	Homo sapiens	Adrenomedullin-2	-	Gs/&β;1/&γ;2; RAMP3	2.3	2020-04-01	10.1021/acsptsci.9b00080
7XBW	A	Protein	Chemokine	CX3CR1	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.8	2022-07-13	10.1126/sciadv.abn8048
7XBX	A	Protein	Chemokine	CX3CR1	Homo sapiens	CX3CL1	-	Gi1/&β;1/&γ;2	3.4	2022-07-13	10.1126/sciadv.abn8048
8IC0	A	Protein	Chemokine	CXCR1	Homo sapiens	Interleukin-8	-	Gi1/&β;1/&γ;2	3.41	2023-07-19	10.1038/s41467-023-39799-2
6LFL	A	Protein	Chemokine	CXCR2	Homo sapiens	-	PubChem 153466996	-	3.2	2020-09-02	10.1038/s41586-020-2492-5
6LFM	A	Protein	Chemokine	CXCR2	Homo sapiens	Interleukin-8	-	Gi1/&β;1/&γ;2	3.5	2020-09-02	10.1038/s41586-020-2492-5
6LFO	A	Protein	Chemokine	CXCR2	Homo sapiens	Interleukin-8	-	Gi1/&β;1/&γ;2	3.4	2020-09-02	10.1038/s41586-020-2492-5
8HNK	A	Protein	Chemokine	CXCR3	Homo sapiens	CXCL11	-	Gi1/&β;1/&γ;2	3.01	2023-11-29	10.1038/s41594-023-01175-5
8HNL	A	Protein	Chemokine	CXCR3	Homo sapiens	PS372424	-	Gi1/&β;1/&γ;2	2.98	2023-11-29	10.1038/s41594-023-01175-5
8HNM	A	Protein	Chemokine	CXCR3	Homo sapiens	VUF11222	-	Gi1/&β;1/&γ;2	2.94	2023-11-29	10.1038/s41594-023-01175-5
8HNN	A	Protein	Chemokine	CXCR3	Homo sapiens	SCH546738	-	-	3.6	2023-11-29	10.1038/s41594-023-01175-5
8K2W	A	Protein	Chemokine	CXCR3	Homo sapiens	AMG487	-	-	3	2023-11-29	10.1038/s41594-023-01175-5
8K2X	A	Protein	Chemokine	CXCR3	Homo sapiens	CXCL10	-	Gi1/&β;1/&γ;2	3.2	2023-11-29	10.1038/s41594-023-01175-5
3ODU	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	2.5	2010-10-27	10.1126/science.1194396
3OE0	A	Protein	Chemokine	CXCR4	Homo sapiens	-	CVX15	-	2.9	2010-10-27	10.1126/science.1194396
3OE6	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.2	2010-10-27	10.1126/science.1194396
3OE8	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
3OE9	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
4RWS	A	Protein	Chemokine	CXCR4	Homo sapiens	vMIP-II	-	-	3.1	2015-02-11	10.1126/science.1261064
8U4N	A	Protein	Chemokine	CXCR4	Homo sapiens	-	Cholesterol	Gi1/&β;1/&γ;2	2.72	2024-03-13	10.1101/2024.02.09.579708
8U4O	A	Protein	Chemokine	CXCR4	Homo sapiens	CXCL12	Cholesterol	Gi1/&β;1/&γ;2	3.29	2024-03-13	10.1101/2024.02.09.579708
8U4P	A	Protein	Chemokine	CXCR4	Homo sapiens	AMD3100	Cholesterol	Gi1/&β;1/&γ;2	3.15	2024-03-13	10.1101/2024.02.09.579708
8U4Q	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	Cholesterol	Gi1/&β;1/&γ;2	3.36	2024-03-13	10.1101/2024.02.09.579708
8U4R	A	Protein	Chemokine	CXCR4	Homo sapiens	REGN7663-Fab	Cholesterol	-	3.1	2024-03-13	10.1101/2024.02.09.579708
6RZ4	A	Lipid	Leukotriene	CysLT₁	Homo sapiens	Pranlukast	Na	-	2.7	2019-10-30	10.1126/sciadv.aax2518
6RZ5	A	Lipid	Leukotriene	CysLT₁	Homo sapiens	Zafirlukast	Na	-	2.53	2019-10-30	10.1126/sciadv.aax2518
6RZ6	A	Lipid	Leukotriene	CysLT₂	Homo sapiens	ONO-2570366	-	-	2.43	2019-12-11	10.1038/s41467-019-13348-2
6RZ7	A	Lipid	Leukotriene	CysLT₂	Homo sapiens	ONO-2570366	-	-	2.43	2019-12-11	10.1038/s41467-019-13348-2
6RZ8	A	Lipid	Leukotriene	CysLT₂	Homo sapiens	ONO-2080365	-	-	2.7	2019-12-11	10.1038/s41467-019-13348-2
6RZ9	A	Lipid	Leukotriene	CysLT₂	Homo sapiens	ONO-2770372	-	-	2.73	2019-12-11	10.1038/s41467-019-13348-2
7CKW	A	Amine	Dopamine	D₁	Homo sapiens	Fenoldopam	-	Gs/&β;1/&γ;2	3.22	2021-03-03	10.1016/j.cell.2021.01.028
7CKX	A	Amine	Dopamine	D₁	Homo sapiens	A77636	-	Gs/&β;1/&γ;2	3.54	2021-03-03	10.1016/j.cell.2021.01.028
7CKY	A	Amine	Dopamine	D₁	Homo sapiens	PW0464	-	Gs/&β;1/&γ;2	3.2	2021-03-03	10.1016/j.cell.2021.01.028
7CKZ	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen	Gs/&β;1/&γ;2	3.1	2021-03-03	10.1016/j.cell.2021.01.028
7CRH	A	Amine	Dopamine	D₁	Homo sapiens	SKF83959	-	Gs/&β;1/&γ;2	3.3	2021-03-03	10.1016/j.cell.2021.01.028
7F0T	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	-	Gs/&β;1/&γ;2	3.1	2022-06-15	10.1126/sciadv.abo4158
7F1O	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP; Mg	Gs/&β;1/&γ;2	3.13	2022-06-15	10.1126/sciadv.abo4158
7F1Z	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP	Gs/&β;1/&γ;2	3.46	2022-06-15	10.1126/sciadv.abo4158
7F23	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP	Gs/&β;1/&γ;2	3.58	2022-06-15	10.1126/sciadv.abo4158
7F24	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP	Gs/&β;1/&γ;2	4.16	2022-06-15	10.1126/sciadv.abo4158
7JOZ	A	Amine	Dopamine	D₁	Homo sapiens	VFP	-	Gs/&β;1/&γ;2	3.8	2021-04-14	10.1038/s41467-021-23519-9
7JV5	A	Amine	Dopamine	D₁	Homo sapiens	SKF81297	-	Gs/&β;1/&γ;2	3	2021-02-24	10.1016/j.cell.2021.01.027
7JVP	A	Amine	Dopamine	D₁	Homo sapiens	SKF83959	-	Gs/&β;1/&γ;2	2.9	2021-02-24	10.1016/j.cell.2021.01.027
7JVQ	A	Amine	Dopamine	D₁	Homo sapiens	Apomorphine	-	Gs/&β;1/&γ;2	3	2021-02-24	10.1016/j.cell.2021.01.027
7LJC	A	Amine	Dopamine	D₁	Homo sapiens	PubChem 86764103	Mevidalen	Gs/&β;1/&γ;2	3	2021-03-03	10.1038/s41422-021-00482-0
7LJD	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen	Gs/&β;1/&γ;1	3.2	2021-03-03	10.1038/s41422-021-00482-0
7X2C	A	Amine	Dopamine	D₁	Homo sapiens	Fenoldopam	Fenoldopam	Gs/&β;1/&γ;2	3.2	2022-06-29	10.1038/s41467-022-30929-w
7X2D	A	Amine	Dopamine	D₁	Homo sapiens	Tavapadon	-	Gs/&β;1/&γ;2	3.3	2022-06-15	10.1038/s41467-022-30929-w
7X2F	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen	Gs/&β;1/&γ;2	3	2022-06-15	10.1038/s41467-022-30929-w
8IRR	A	Amine	Dopamine	D₁	Homo sapiens	Rotigotine	-	Gs/&β;1/&γ;2	3.2	2023-06-07	10.1038/s41422-023-00808-0
6CM4	A	Amine	Dopamine	D₂	Homo sapiens	Risperidone	-	-	2.87	2018-03-14	10.1038/nature25758
6LUQ	A	Amine	Dopamine	D₂	Homo sapiens	Haloperidol	-	-	3.1	2020-03-04	10.1038/s41467-020-14884-y
6VMS	A	Amine	Dopamine	D₂	Homo sapiens	Bromoergocryptine	-	Gi1/&β;1/&γ;2	3.8	2020-06-17	10.1038/s41586-020-2379-5
7DFP	A	Amine	Dopamine	D₂	Homo sapiens	Spiperone	-	-	3.1	2020-12-30	10.1038/s41467-020-20221-0
7JVR	A	Amine	Dopamine	D₂	Homo sapiens	Bromoergocryptine	-	Gi1/&β;1/&γ;2	2.8	2021-02-24	10.1016/j.cell.2021.01.027
8IRS	A	Amine	Dopamine	D₂	Homo sapiens	Rotigotine	-	Gi1/&β;1/&γ;2	3	2023-06-07	10.1038/s41422-023-00808-0
3PBL	A	Amine	Dopamine	D₃	Homo sapiens	Eticlopride	-	-	2.89	2010-11-03	10.1126/science.1197410
7CMU	A	Amine	Dopamine	D₃	Homo sapiens	Pramipexole	-	Gi1/&β;1/&γ;2	3	2021-03-10	10.1016/j.molcel.2021.01.003
7CMV	A	Amine	Dopamine	D₃	Homo sapiens	PD128907	-	Gi1/&β;1/&γ;2	2.7	2021-03-10	10.1016/j.molcel.2021.01.003
8IRT	A	Amine	Dopamine	D₃	Homo sapiens	Rotigotine	-	Gi1/&β;1/&γ;2	2.7	2023-06-07	10.1038/s41422-023-00808-0
5WIU	A	Amine	Dopamine	D₄	Homo sapiens	Nemonapride	-	-	1.96	2017-10-18	10.1126/science.aan5468
5WIV	A	Amine	Dopamine	D₄	Homo sapiens	Nemonapride	Na	-	2.14	2017-10-18	10.1126/science.aan5468
6IQL	A	Amine	Dopamine	D₄	Mus musculus	L745870	-	-	3.5	2019-12-04	10.7554/eLife.48822
8IRU	A	Amine	Dopamine	D₄	Homo sapiens	Rotigotine	-	chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2	3.2	2023-06-07	10.1038/s41422-023-00808-0
8IRV	A	Amine	Dopamine	D₅	Homo sapiens	Rotigotine	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2023-06-07	10.1038/s41422-023-00808-0
4EJ4	A	Peptide	Opioid	δ	Mus musculus	Naltrindole	-	-	3.4	2012-05-16	10.1038/nature11111
4N6H	A	Peptide	Opioid	δ	Homo sapiens	Naltrindole	Na	-	1.8	2013-12-25	10.1038/nature12944
4RWA	A	Peptide	Opioid	δ	Homo sapiens	DIPP-NH2	-	-	3.28	2015-01-14	10.1038/nsmb.2965
4RWD	A	Peptide	Opioid	δ	Homo sapiens	DIPP-NH2	Na	-	2.7	2015-01-14	10.1038/nsmb.2965
6PT2	A	Peptide	Opioid	δ	Homo sapiens	KGCHM07	-	-	2.8	2019-12-11	10.1126/sciadv.aax9115
6PT3	A	Peptide	Opioid	δ	Homo sapiens	DPI-287	-	-	3.3	2019-12-11	10.1126/sciadv.aax9115
8F7S	A	Peptide	Opioid	δ	Homo sapiens	Deltorphin	-	Gi1/&β;1/&γ;2	3	2022-12-14	10.1016/j.cell.2022.12.026
6D26	A	Lipid	Prostanoid	DP₂	Homo sapiens	Fevipiprant	-	-	2.8	2018-10-03	10.1016/j.molcel.2018.08.009
6D27	A	Lipid	Prostanoid	DP₂	Homo sapiens	CAY10471	-	-	2.74	2018-10-03	10.1016/j.molcel.2018.08.009
7M8W	A	Lipid	Prostanoid	DP₂	Homo sapiens	15r-Methyl-Prostaglandin D2	Na	-	2.61	2021-08-25	10.1073/pnas.2102813118
7CX2	A	Lipid	Prostanoid	EP₂	Homo sapiens	PGE2	-	Gs/&β;1/&γ;2	2.8	2021-05-05	10.1126/sciadv.abf1268
7CX3	A	Lipid	Prostanoid	EP₂	Homo sapiens	Taprenepag	-	Gs/&β;1/&γ;2	2.8	2021-05-05	10.1126/sciadv.abf1268
7CX4	A	Lipid	Prostanoid	EP₂	Homo sapiens	Evatanepag	-	Gs/&β;1/&γ;2	2.9	2021-05-05	10.1126/sciadv.abf1268
6AK3	A	Lipid	Prostanoid	EP₃	Homo sapiens	Dinoprostone IPGE2	-	-	2.9	2018-12-05	10.1038/s41589-018-0171-8
6M9T	A	Lipid	Prostanoid	EP₃	Homo sapiens	Misoprostol-FA	-	-	2.5	2018-12-05	10.1038/s41589-018-0160-y
7WU9	A	Lipid	Prostanoid	EP₃	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.38	2022-08-17	10.1016/j.celrep.2022.111323
8GDC	A	Lipid	Prostanoid	EP₃	Homo sapiens	PGE2	-	Gi1/&β;1/&γ;2	3.5	2024-01-03	10.1073/pnas.2216329120
5YHL	A	Lipid	Prostanoid	EP₄	Homo sapiens	PubChem 135121352	-	-	4.2	2018-12-05	10.1038/s41589-018-0131-3
5YWY	A	Lipid	Prostanoid	EP₄	Homo sapiens	ONO-AE3-208	-	-	3.2	2018-12-05	10.1038/s41589-018-0131-3
7D7M	A	Lipid	Prostanoid	EP₄	Homo sapiens	Dinoprostone	-	Gs/&β;1/&γ;1	3.3	2020-11-18	10.1016/j.str.2020.11.007
8GCM	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-	Gi1/&β;1/&γ;2	3.5	2024-01-03	10.1073/pnas.2216329120
8GCP	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-	Gi1/&β;1/&γ;2	3.1	2024-01-03	10.1073/pnas.2216329120
8GD9	A	Lipid	Prostanoid	EP₄	Homo sapiens	Rivenprost	-	Gs/&β;1/&γ;2	3.2	2024-01-03	10.1073/pnas.2216329120
8GDA	A	Lipid	Prostanoid	EP₄	Homo sapiens	L902688	-	Gs/&β;1/&γ;2	3.3	2024-01-03	10.1073/pnas.2216329120
8GDB	A	Lipid	Prostanoid	EP₄	Homo sapiens	PGE2	-	Gs/&β;1/&γ;2	3.1	2024-01-03	10.1073/pnas.2216329120
8HCQ	A	Peptide	Endothelin	ET_A	Homo sapiens	Endothelin-1	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.01	2023-03-22	10.1038/s41467-023-36998-9
5GLH	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	-	2.8	2016-09-07	10.1038/nature19319
5GLI	A	Peptide	Endothelin	ET_B	Homo sapiens	-	-	-	2.5	2016-09-07	10.1038/nature19319
5X93	A	Peptide	Endothelin	ET_B	Homo sapiens	K-8794	-	-	2.2	2017-08-16	10.1038/nsmb.3450
5XPR	A	Peptide	Endothelin	ET_B	Homo sapiens	Bosentan	-	-	3.6	2017-08-16	10.1038/nsmb.3450
6IGK	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-3	-	-	2	2018-11-21	10.1038/s41467-018-07094-0
6IGL	A	Peptide	Endothelin	ET_B	Homo sapiens	IRL1620	-	-	2.7	2018-11-21	10.1038/s41467-018-07094-0
6K1Q	A	Peptide	Endothelin	ET_B	Homo sapiens	IRL2500	-	-	2.7	2019-07-17	10.1038/s42003-019-0482-7
6LRY	A	Peptide	Endothelin	ET_B	Homo sapiens	Sarafotoxin-B	-	-	3	2020-02-12	10.1016/j.bbrc.2019.12.091
8HBD	A	Peptide	Endothelin	ET_B	Homo sapiens	IRL1620	-	Gi1/&β;1/&γ;2	2.99	2023-03-22	10.1038/s41467-023-36998-9
8HCX	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.5	2023-03-22	10.1038/s41467-023-36998-9
8IY5	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	Gi1/&β;1/&γ;2	2.8	2023-08-16	10.7554/eLife.85821
8IY6	A	Peptide	Endothelin	ET_B	Homo sapiens	Endothelin-1	-	-	3.13	2023-08-16	10.7554/eLife.85821
8T3V	A	Lipid	Free fatty acid	FFA1	Homo sapiens	DHA	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.39	2024-01-24	10.1126/sciadv.adj2384
4PHU	A	Lipid	Free fatty acid	FFA1 (GPR40)	Homo sapiens	-	Fasiglifam	-	2.33	2014-07-16	10.1038/nature13494
5KW2	A	Lipid	Free fatty acid	FFA1 (GPR40)	Homo sapiens	-	PubChem 133053953	-	2.76	2018-05-02	10.1038/s41467-017-01240-w
5TZR	A	Lipid	Free fatty acid	FFA1 (GPR40)	Homo sapiens	-	MK8666	-	2.2	2017-06-07	10.1038/nsmb.3417
5TZY	A	Lipid	Free fatty acid	FFA1 (GPR40)	Homo sapiens	-	MK8666; PubChem 127053597	-	3.22	2017-06-07	10.1038/nsmb.3417
8EIT	A	Lipid	Free fatty acid	FFA1 (GPR40)	Homo sapiens	Doconexent	-	chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2	2.8	2023-05-24	10.1073/pnas.2219569120
8EJC	A	Lipid	Free fatty acid	FFA1 (GPR40)	Homo sapiens	TAK-875	-	chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2	3	2023-05-24	10.1073/pnas.2219569120
8EJK	A	Lipid	Free fatty acid	FFA1 (GPR40)	Homo sapiens	TAK-875	-	chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2	3.4	2023-05-24	10.1073/pnas.2219569120
8J22	A	Lipid	Free fatty acid	FFA2	Homo sapiens	TUG-1375	-	Gi1/&β;1/&γ;2	3.2	2024-01-24	10.1038/s41422-023-00914-z
8J23	A	Lipid	Free fatty acid	FFA2	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.2	2024-04-17	To be published
8J24	A	Lipid	Free fatty acid	FFA2	Homo sapiens	Acetic acid	-	Gi1/&β;1/&γ;2	2.6	2024-01-24	10.1038/s41422-023-00914-z
8T3S	A	Lipid	Free fatty acid	FFA2	Homo sapiens	Butyric acid	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.07	2024-01-24	10.1126/sciadv.adj2384
8J20	A	Lipid	Free fatty acid	FFA3	Homo sapiens	Valeric acid	AR420626	Gi1/&β;1/&γ;2	3.2	2024-01-24	10.1038/s41422-023-00914-z
8J21	A	Lipid	Free fatty acid	FFA3	Homo sapiens	Butyric acid	-	Gi1/&β;1/&γ;2	3.3	2024-01-24	10.1038/s41422-023-00914-z
8H4I	A	Lipid	Free fatty acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.06	2023-06-21	10.1038/s41422-023-00835-x
8H4K	A	Lipid	Free fatty acid	FFA4	Homo sapiens	GW9508	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.1	2023-06-21	10.1038/s41422-023-00835-x
8H4L	A	Lipid	Free fatty acid	FFA4	Homo sapiens	Doconexent	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.07	2023-06-21	10.1038/s41422-023-00835-x
8IYS	A	Lipid	Free fatty acid	FFA4	Homo sapiens	TUG-891	GDP	chim(NtGi1L-Gq)/&β;1/&γ;2	2.95	2023-06-21	10.1038/s41422-023-00835-x
8T3O	A	Lipid	Free fatty acid	FFA4	Homo sapiens	TUG-891	2Y5	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.06	2024-01-17	10.1126/sciadv.adj2384
8T3Q	A	Lipid	Free fatty acid	FFA4	Homo sapiens	DHA	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.14	2024-01-24	10.1126/sciadv.adj2384
8G59	A	Lipid	Free fatty acid	FFA4 (GPR120)	Homo sapiens	TUG-891	-	Gi1/&β;1/&γ;2	2.64	2023-03-08	10.1126/science.add6220
8ID3	A	Lipid	Free fatty acid	FFA4 (GPR120)	Homo sapiens	9-Hydroxystearic acid	-	Gi1/&β;1/&γ;2	3.1	2023-03-15	10.1126/science.add6220
8ID4	A	Lipid	Free fatty acid	FFA4 (GPR120)	Homo sapiens	Linoleic acid	-	Gi1/&β;1/&γ;2	3.1	2023-03-15	10.1126/science.add6220
8ID6	A	Lipid	Free fatty acid	FFA4 (GPR120)	Homo sapiens	Oleic acid	-	Gi1/&β;1/&γ;2	2.8	2023-03-15	10.1126/science.add6220
8ID8	A	Lipid	Free fatty acid	FFA4 (GPR120)	Homo sapiens	TUG-891	-	Gi1/&β;1/&γ;2	3	2023-03-15	10.1126/science.add6220
8ID9	A	Lipid	Free fatty acid	FFA4 (GPR120)	Homo sapiens	Eicosapentaenoic acid	-	Gi1/&β;1/&γ;2	3	2023-03-15	10.1126/science.add6220
8IQ4	A	Lipid	Prostanoid	FP-alpha	Homo sapiens	Carboprost	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.7	2024-01-31	10.1038/s41467-023-43922-8
8IQ6	A	Lipid	Prostanoid	FP-alpha	Homo sapiens	Latanoprost	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.4	2024-01-31	10.1038/s41467-023-43922-8
8IUK	A	Lipid	Prostanoid	FP-alpha	Homo sapiens	PGF2-alpha	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.67	2023-07-12	10.1038/s41467-023-38411-x
8IUL	A	Lipid	Prostanoid	FP-alpha	Homo sapiens	Latanoprost	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.78	2023-07-12	10.1038/s41467-023-38411-x
8IUM	A	Lipid	Prostanoid	FP-alpha	Homo sapiens	Tafluprost acid	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.14	2023-07-12	10.1038/s41467-023-38411-x
8XJL	A	Lipid	Prostanoid	FP-alpha	Homo sapiens	PGF2-alpha	-	chim(NtGi2-Gs-CtGq)/&β;1/&γ;2	2.77	2024-02-28	To be published
8XJM	A	Lipid	Prostanoid	FP-alpha	Homo sapiens	Latanoprost	-	chim(NtGi2-Gs-CtGq)/&β;1/&γ;2	2.85	2024-02-28	To be published
7EUO	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLF	-	Gi1/&β;1/&γ;2	2.9	2022-05-25	10.1038/s41467-022-32822-y
7T6T	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLFII	-	Gi1/&β;1/&γ;2	3.2	2022-03-30	10.1038/s41467-022-28586-0
7VFX	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLF	-	Gi1/&β;1/&γ;2	2.8	2022-09-21	10.1038/s41467-022-32822-y
7WVU	A	Peptide	Formylpeptide	FPR1-ALX	Homo sapiens	fMLF	-	Gi1/&β;1/&γ;2	3.3	2022-04-13	10.1038/s41467-022-29361-x
6LW5	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVm	-	-	2.8	2020-03-25	10.1038/s41467-020-15009-1
6OMM	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	WKYMVX	-	Gi1/&β;1/&γ;2	3.17	2020-02-26	10.1038/s41467-020-14728-9
7T6S	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	PubChem 24776341	-	Gi1/&β;1/&γ;2	3	2022-03-30	10.1038/s41467-022-28586-0
7T6U	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	CGEN-855A	-	Gi1/&β;1/&γ;2	2.9	2022-03-30	10.1038/s41467-022-28586-0
7T6V	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-	Gi1/&β;1/&γ;2	3.1	2022-03-30	10.1038/s41467-022-28586-0
7WVV	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMLFII	-	Gi2/&β;1/&γ;2	2.9	2022-04-13	10.1038/s41467-022-29361-x
7WVW	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	fMYFINILTL	-	Gi2/&β;1/&γ;2	3.1	2022-04-13	10.1038/s41467-022-29361-x
7WVX	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Humanin	-	Gi2/&β;1/&γ;2	2.8	2022-04-13	10.1038/s41467-022-29361-x
7WVY	A	Peptide	Formylpeptide	FPR2-ALX	Homo sapiens	Amyloid-Beta42	-	Gi2/&β;1/&γ;2	3	2022-04-13	10.1038/s41467-022-29361-x
8I2G	A	Protein	Glycoprotein hormone	FSH	Homo sapiens	Glycoprotein hormones alpha chain	Compound 716340	Gs/&β;1/&γ;2	2.8	2023-03-29	10.1038/s41467-023-36170-3
8I2H	A	Protein	Glycoprotein hormone	FSH	Homo sapiens	-	-	-	6	2023-03-22	10.1038/s41467-023-36170-3
8J9N	F	Protein	Frizzled	FZD₁	Homo sapiens	-	-	chim(Gs-CtGq)/&β;1/&γ;2	3.5	2024-01-17	10.1038/s41421-023-00627-y
8J9O	F	Protein	Frizzled	FZD₁	Homo sapiens	-	-	-	3.4	2024-01-17	10.1038/s41421-023-00627-y
8JHC	F	Protein	Frizzled	FZD₃	Homo sapiens	-	-	-	3.3	2024-01-17	10.1038/s41421-023-00627-y
8JHI	F	Protein	Frizzled	FZD₃	Homo sapiens	-	-	chim(NtGsXLas-Gs)/&β;1/&γ;2	3.2	2024-01-17	10.1038/s41421-023-00627-y
6BD4	F	Protein	Frizzled	FZD₄	Homo sapiens	-	-	-	2.4	2018-08-22	10.1038/s41586-018-0447-x
6WW2	F	Protein	Frizzled	FZD₅	Homo sapiens	-	-	-	3.7	2020-08-19	10.7554/eLife.58464
8JH7	F	Protein	Frizzled	FZD₆	Homo sapiens	-	-	-	3.2	2024-01-17	10.1038/s41421-023-00627-y
8JHB	F	Protein	Frizzled	FZD₆	Homo sapiens	-	-	chim(NtGsXLas-Gs)/&β;1/&γ;2	3.3	2024-01-17	10.1038/s41421-023-00627-y
7EVW	F	Protein	Frizzled	FZD₇	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.22	2021-08-04	10.1038/s41422-021-00525-6
8YY8	F	Protein	Frizzled	FZD₇	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.22	2024-04-24	10.1038/s41422-021-00525-6
6W2Y	C	Aminoacid	GABAB	GABAB1; GABAB1	Homo sapiens	PubChem 5311042	PubChem 23727970	-	3.2	2020-07-01	10.1038/s41586-020-2469-4
6UO8	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	GS39783	-	3.63	2020-06-10	10.1038/s41586-020-2408-4
6UO9	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	SKF97541	-	-	4.8	2020-06-10	10.1038/s41586-020-2408-4
6UOA	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	6.3	2020-06-10	10.1038/s41586-020-2408-4
6VJM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	3.97	2020-06-10	10.1038/s41586-020-2408-4
6W2X	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	PubChem 5311042	PubChem 23727970	-	3.6	2020-07-01	10.1038/s41586-020-2469-4
6WIV	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	PubChem 52923113; PubChem 52924645	-	3.3	2020-07-01	10.1038/s41586-020-2452-0
7C7Q	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	Baclofen	PubChem 7023848	-	3	2020-07-01	10.1038/s41422-020-0350-5
7C7S	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	-	-	2.9	2020-07-01	10.1038/s41422-020-0350-5
7CA3	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	rac-BHFF	-	4.5	2020-11-11	10.1016/j.jmb.2020.09.023
7CA5	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	-	-	-	7.6	2020-11-11	10.1016/j.jmb.2020.09.023
7CUM	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	CGP54626	Phospholipid	-	3.52	2020-11-11	10.1016/j.jmb.2020.09.023
7EB2	C	Aminoacid	GABAB	GABA_B1, GABA_B2	Homo sapiens	Baclofen	rac-BHFF	Gi1/&β;1/&γ;2	3.5	2021-05-05	10.1038/s41586-021-03507-1
7WQ3	A	Peptide	Galanin	GAL₁	Homo sapiens	Galanin	-	Gi1/&β;1/&γ;2	2.7	2022-04-20	10.1038/s41467-022-29072-3
7XJJ	A	Peptide	Galanin	GAL₁	Homo sapiens	Galanin	-	Go/&β;1/&γ;2	3.3	2023-05-03	10.1073/pnas.2121465119
7WQ4	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.6	2022-04-20	10.1038/s41467-022-29072-3
7XBD	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.11	2022-07-13	10.1371/journal.pbio.3001714
7XJK	A	Peptide	Galanin	GAL₂	Homo sapiens	Galanin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.3	2022-06-29	10.1073/pnas.2121465119
7XJL	A	Peptide	Galanin	GAL₂	Homo sapiens	Spexin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.5	2022-06-29	10.1073/pnas.2121465119
6KO5	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	PubChem 57400002	-	-	3.3	2020-08-12	10.1038/s41467-020-17554-1
7F83	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	PF-05190457	-	-	2.94	2022-01-19	10.1038/s41467-022-27975-9
7F9Y	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin-28	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.9	2021-08-18	10.1038/s41467-021-25364-2
7F9Z	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	GHRP-6	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.2	2021-08-18	10.1038/s41467-021-25364-2
7NA7	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin-27	-	Gi1/&β;1/&γ;2	2.7	2021-12-15	10.1038/s41467-021-26735-5
7NA8	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	PubChem 178024	-	Gi1/&β;1/&γ;2	2.7	2021-12-15	10.1038/s41467-021-26735-5
7W2Z	A	Peptide	Ghrelin	Ghrelin	Homo sapiens	Ghrelin	-	Go/&β;1/&γ;2	2.8	2022-01-19	10.1038/s41467-022-27975-9
7CZ5	B1	Peptide	Glucagon	GHRH	Homo sapiens	Somatoliberin	-	Gs/&β;1/&γ;2	2.6	2020-11-18	10.1038/s41467-020-18945-0
7V9L	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.6	2022-04-06	10.1073/pnas.2106606118
7V9M	B1	Peptide	Glucagon	GHRH (SV1)	Homo sapiens	Somatoliberin	-	Gs/&β;1/&γ;2	3.29	2021-10-20	10.1073/pnas.2106606118
7DTY	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	Gs/&β;1/&γ;2	2.98	2021-08-04	10.7554/eLife.68719
7FIN	B1	Peptide	Glucagon	GIP	Homo sapiens	Peptide-20; GGL	-	Gs/&β;1/&γ;2	3.1	2022-02-23	10.1038/s41467-022-28683-0
7FIY	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	-	Gs/&β;1/&γ;2	3.4	2022-03-02	10.1038/s41467-022-28683-0
7RA3	B1	Peptide	Glucagon	GIP	Homo sapiens	GIP	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.24	2022-04-13	10.1073/pnas.2116506119
7RBT	B1	Peptide	Glucagon	GIP	Homo sapiens	Tirzepatide	PubChem 163183774	chim(NtGi1-Gs)/&β;1/&γ;2	3.08	2022-04-13	10.1073/pnas.2116506119
7VAB	B1	Peptide	Glucagon	GIP	Homo sapiens	Non-Acylated Tirzepatide	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2022-03-02	10.1038/s41467-022-28683-0
8ITL	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.23	2023-10-18	10.1073/pnas.2306145120
8ITM	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.13	2023-10-18	10.1073/pnas.2306145120
8WA3	B1	Peptide	Glucagon	GIP	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.86	2024-03-06	10.1038/s41421-024-00649-0
5NX2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1 (Truncated)	-	-	3.7	2017-06-14	10.1038/nature22800
5VAI	B1	Peptide	Glucagon	GLP-1	Oryctolagus cuniculus	GLP-1	-	Gs/&β;1/&γ;2	4.1	2017-05-24	10.1038/nature22394
5VEW	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PF-06372222	-	2.7	2017-05-24	10.1038/nature22378
5VEX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	NNC0640	-	3	2017-05-17	10.1038/nature22378
6B3J	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-P5	-	Gs/&β;1/&γ;2	3.3	2018-02-21	10.1038/nature25773
6KJV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
6KK1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	2.8	2019-11-13	10.1107/S2052252519013496
6KK7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.1	2019-11-13	10.1107/S2052252519013496
6LN2	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 68178630	-	3.2	2020-03-18	10.1038/s41467-020-14934-5
6ORV	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	TT-OAD2	Gs/&β;1/&γ;2	3	2020-01-08	10.1038/s41586-019-1902-z
6VCB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	LSN3160440	Gs/&β;1/&γ;2	3.3	2020-07-22	10.1038/s41589-020-0589-7
6X18	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
6X19	B1	Peptide	Glucagon	GLP-1	Homo sapiens	CHU-128	-	Gs/&β;1/&γ;2	2.1	2020-09-09	10.1016/j.molcel.2020.09.020
6X1A	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.5	2020-09-09	10.1016/j.molcel.2020.09.020
6XOX	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2020-11-18	10.1073/pnas.2014879117
7C2E	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 149050799	-	Gs/&β;1/&γ;2	4.2	2020-08-26	10.1038/s41422-020-0384-8
7DUQ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	GLP-1	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-07-14	10.1038/s41467-021-24058-z
7DUR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	3.3	2021-08-11	10.1038/s41467-021-24058-z
7E14	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Orforglipron	PubChem 156022738	Gs/&β;1/&γ;2	2.9	2021-07-07	10.1038/s41467-021-24058-z
7EVM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	PubChem 156022738	Gs/&β;1/&γ;2	2.5	2021-08-11	10.1038/s41467-021-24058-z
7FIM	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	Gs/&β;1/&γ;2	3.4	2022-03-02	10.1038/s41467-022-28683-0
7KI0	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Semaglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
7KI1	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Taspoglutide	-	Gs/&β;1/&γ;2	2.5	2021-08-04	10.1016/j.celrep.2021.109374
7LCI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	Gs/&β;1/&γ;2	2.9	2021-01-20	10.1016/j.str.2021.04.008
7LCJ	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	2.82	2021-01-20	10.1016/j.str.2021.04.008
7LCK	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Danuglipron	-	-	3.24	2021-01-20	10.1016/j.str.2021.04.008
7LLL	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Exendin-4	-	Gs/&β;1/&γ;2	3.7	2022-01-12	10.1038/s41467-021-27760-0
7LLY	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Oxyntomodulin	-	Gs/&β;1/&γ;2	3.3	2022-01-12	10.1038/s41467-021-27760-0
7RG9	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2022-04-13	10.1073/pnas.2116506119
7RGP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Tirzepatide	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2022-04-13	10.1073/pnas.2116506119
7RTB	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-19	-	Gs/&β;1/&γ;2	2.14	2021-10-06	10.1016/j.bbrc.2021.09.016
7S15	B1	Peptide	Glucagon	GLP-1	Homo sapiens	PubChem 134611223	-	-	3.8	2022-06-08	10.1021/acs.jmedchem.1c01856
7S1M	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Ex4-D-Ala	-	Gs/&β;1/&γ;2	2.41	2022-01-05	10.1038/s41589-021-00945-w
7S3I	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.51	2022-01-05	10.1038/s41589-021-00945-w
7VBH	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-20	-	Gs/&β;1/&γ;2	3	2022-04-06	10.1038/s41467-022-28683-0
7VBI	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Non-Acylated Tirzepatide	-	Gs/&β;1/&γ;2	3	2022-03-02	10.1038/s41467-022-28683-0
7X8R	B1	Peptide	Glucagon	GLP-1	Homo sapiens	BOC5	-	Gs/&β;1/&γ;2	2.61	2022-06-29	10.1073/pnas.2200155119
7X8S	B1	Peptide	Glucagon	GLP-1	Homo sapiens	WB4-24	-	Gs/&β;1/&γ;2	3.09	2022-06-29	10.1073/pnas.2200155119
8JIP	B1	Peptide	Glucagon	GLP-1	Homo sapiens	MEDI0382	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.85	2023-09-06	10.1073/pnas.2303696120
8JIR	B1	Peptide	Glucagon	GLP-1	Homo sapiens	SAR425899	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.57	2023-09-06	10.1073/pnas.2303696120
8JIS	B1	Peptide	Glucagon	GLP-1	Homo sapiens	Peptide-15	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.46	2023-11-08	10.1073/pnas.2303696120
8WG7	B1	Peptide	Glucagon	GLP-1	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.54	2024-03-06	10.1038/s41421-024-00649-0
7D68	B1	Peptide	Glucagon	GLP-2	Homo sapiens	GLP-2	-	Gs/&β;1/&γ;2	3	2020-12-16	10.1038/s41422-020-00442-0
4L6R	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	-	3.3	2013-07-24	10.1038/nature12393
5EE7	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	MK0893	-	2.5	2016-04-20	10.1038/nature17414
5XEZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3	2017-05-24	10.1038/nature22363
5XF1	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	NNC0640	-	3.19	2017-05-24	10.1038/nature22363
5YQZ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon analogue	-	-	3	2018-01-17	10.1038/nature25153
6LMK	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Gs/&β;1/&γ;2	3.7	2020-04-01	10.1126/science.aaz5346
6LML	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	-	3.9	2020-04-01	10.1126/science.aaz5346
6WHC	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glu16 analog of GCG	-	Gs/&β;1/&γ;2	3.4	2020-05-27	10.1074/jbc.RA120.013793
6WPW	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/&β;1/&γ;2	3.1	2020-08-12	10.1126/science.aba3373
7V35	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-20	-	Gs/&β;1/&γ;2	3.5	2022-03-02	10.1038/s41467-022-28683-0
8FU6	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon derivative ZP3780	-	Gs/&β;1/&γ;2	2.9	2023-04-12	10.1016/j.cell.2023.02.028
8JIQ	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Peptide-15	-	Gs/&β;1/&γ;2	3.4	2023-09-13	10.1073/pnas.2303696120
8JIT	B1	Peptide	Glucagon	Glucagon	Homo sapiens	MEDI0382	-	Gs/&β;1/&γ;2	2.91	2023-09-06	10.1073/pnas.2303696120
8JIU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	SAR425899	-	Gs/&β;1/&γ;2	2.76	2023-09-13	10.1073/pnas.2303696120
8JRU	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	-	Arrestin2	3.5	2023-08-16	10.1038/s41586-023-06420-x
8JRV	B1	Peptide	Glucagon	Glucagon	Homo sapiens	Glucagon	-	Arrestin2	3.3	2023-08-16	10.1038/s41586-023-06420-x
8WG8	B1	Peptide	Glucagon	Glucagon	Homo sapiens	-	Peptide	chim(NtGi1-Gs)/&β;1/&γ;2	2.71	2024-03-06	10.1038/s41421-024-00649-0
7BR3	A	Protein	Gonadotrophin Releasing Hormone	GnRH₁	Homo sapiens	Elagolix	-	-	2.79	2020-10-07	10.1038/s41467-020-19109-w
7BW0	A	Steroid	Bile acid	GPBA	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.9	2020-09-02	10.1038/s41392-020-00262-z
7CFM	A	Steroid	Bile acid	GPBA	Homo sapiens	P395	-	Gs/&β;1/&γ;2	3	2020-09-09	10.1038/s41586-020-2569-1
7CFN	A	Steroid	Bile acid	GPBA	Homo sapiens	INT-777	-	Gs/&β;1/&γ;2	3	2020-09-09	10.1038/s41586-020-2569-1
7XTQ	A	Steroid	Bile acid	GPBA	Homo sapiens	R399	-	Gs/&β;1/&γ;2	3.2	2022-07-06	10.1073/pnas.2117054119
8XOG	A	Steroid	Estrogen	GPER1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.9	2024-04-10	To be published
8XOH	A	Steroid	Estrogen	GPER1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.2	2024-04-10	To be published
8XOI	A	Steroid	Estrogen	GPER1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.2	2024-04-10	To be published
8XOJ	A	Steroid	Estrogen	GPER1	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.1	2024-04-10	To be published
8W8Q	A	Orphan	A orphans	GPR101	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.89	2024-01-03	10.1038/s41589-023-01456-6
8W8R	A	Orphan	A orphans	GPR101	Homo sapiens	-	AA-14	chim(NtGi1-Gs)/&β;1/&γ;2	3.3	2024-01-03	10.1038/s41589-023-01456-6
8W8S	A	Orphan	A orphans	GPR101	Homo sapiens	-	AA-14	-	3.3	2024-01-03	10.1038/s41589-023-01456-6
7WCM	A	Lipid	GPR119	GPR119	Homo sapiens	MBX-2982	-	Gs/&β;1/&γ;2	2.33	2022-12-21	10.1038/s41467-022-34696-6
7WCN	A	Lipid	GPR119	GPR119	Homo sapiens	AR231453	-	Gs/&β;1/&γ;2	2.87	2022-12-21	10.1038/s41467-022-34696-6
7XZ5	A	Lipid	GPR119	GPR119	Homo sapiens	Lysophosphatidylcholine	-	Gs/&β;1/&γ;2	3.1	2022-08-24	10.1038/s41594-022-00816-5
7XZ6	A	Lipid	GPR119	GPR119	Homo sapiens	APD668	-	Gs/&β;1/&γ;2	2.8	2022-08-24	10.1038/s41594-022-00816-5
7Y3G	A	Orphan	A orphans	GPR12	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.77	2023-06-07	10.1016/j.scib.2022.12.023
8HQE	A	Orphan	A orphans	GPR132	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.97	2023-10-11	0.1038/s42255-023-00899-4
8HQM	A	Orphan	A orphans	GPR132	Homo sapiens	NPGLY	-	Gi1/&β;1/&γ;2	2.95	2023-10-11	0.1038/s42255-023-00899-4
8HQN	A	Orphan	A orphans	GPR132	Homo sapiens	9(S)-HODE	-	Gi1/&β;1/&γ;2	3	2023-10-11	0.1038/s42255-023-00899-4
8HVI	A	Orphan	A orphans	GPR132	Homo sapiens	NOX-6-7	-	Gi1/&β;1/&γ;2	3.04	2023-10-11	0.1038/s42255-023-00899-4
7VUG	A	Orphan	A orphans	GPR139	Homo sapiens	JNJ-63533054	-	Gi1/&β;1/&γ;2	3.2	2021-12-29	10.1038/s41422-021-00591-w
7VUH	A	Orphan	A orphans	GPR139	Homo sapiens	JNJ-63533054	-	chim(Gs-CtGq)/&β;1/&γ;2	3.22	2021-12-29	10.1038/s41422-021-00591-w
7VUI	A	Orphan	A orphans	GPR139	Homo sapiens	JNJ-63533054	GTP	chim(Gs-CtGq)/&β;1/&γ;2	3.3	2021-12-29	10.1038/s41422-021-00591-w
7VUJ	A	Orphan	A orphans	GPR139	Homo sapiens	JNJ-63533054	GDP	chim(Gs-CtGq)/&β;1/&γ;2	3.8	2021-12-29	10.1038/s41422-021-00591-w
7EWL	C	Orphan	C orphans	GPR158	Homo sapiens	-	-	-	3.52	2021-12-01	10.1038/s41467-021-27147-1
7EWP	C	Orphan	C orphans	GPR158	Homo sapiens	-	-	B5; RGS7	4.3	2021-12-01	10.1038/s41467-021-27147-1
7EWR	C	Orphan	C orphans	GPR158	Homo sapiens	-	-	B5; RGS7	4.7	2021-12-01	10.1038/s41467-021-27147-1
7SHE	C	Orphan	C orphans	GPR158	Homo sapiens	-	PI; PE	-	3.4	2021-12-01	10.1126/science.abl4732
7SHF	C	Orphan	C orphans	GPR158	Homo sapiens	-	PI; PE	B5; RGS7	3.4	2021-12-01	10.1126/science.abl4732
8KH4	A	Orphan	A orphans	GPR161	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.1	2023-10-11	10.1038/s41467-023-41654-3
8SMV	A	Orphan	A orphans	GPR161	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.74	2024-02-21	10.1038/s41594-024-01223-8
7Y89	A	Orphan	A orphans	GPR17 (CysLT)	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.02	2022-10-12	10.1002/mco2.159
7XV3	A	Orphan	A orphans	GPR174	Homo sapiens	Lysophosphatidylserine	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.76	2023-02-15	10.1038/s41467-023-36575-0
8IZB	A	Orphan	A orphans	GPR174	Homo sapiens	Lysophosphatidylserine	-	Gs/&β;1/&γ;2	3.06	2023-11-01	10.1371/journal.pbio.3002387
8KH5	A	Orphan	A orphans	GPR174	Homo sapiens	Lysophosphatidylserine	-	Gs/&β;1/&γ;2	2.83	2023-10-11	10.1038/s41467-023-41654-3
7TUY	A	Orphan	A orphans	GPR183	Homo sapiens	GSK682753A	-	-	2.98	2022-04-13	10.1016/j.str.2022.04.006
7TUZ	A	Orphan	A orphans	GPR183	Homo sapiens	7alpha,25-dihydroxycholesterol	-	Gi1/&β;1/&γ;2	3.12	2022-04-13	10.1016/j.str.2022.04.006
8HS2	A	Orphan	A orphans	GPR20	Homo sapiens	Fab046	-	-	3.08	2023-03-08	10.1038/s41421-023-00520-8
8HS3	A	Orphan	A orphans	GPR20	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.14	2023-03-08	10.1038/s41421-023-00520-8
8HSC	A	Orphan	A orphans	GPR20	Homo sapiens	Fab046	-	Gi1/&β;1/&γ;2	3.22	2023-03-08	10.1038/s41421-023-00520-8
8HIX	A	Orphan	A orphans	GPR21	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.12	2023-03-15	10.1038/s41467-023-35882-w
8HJ0	A	Orphan	A orphans	GPR21	Homo sapiens	-	-	chim(Gs-CtG15)/&β;1/&γ;2	3.12	2023-03-15	10.1038/s41467-023-35882-w
8HJ1	A	Orphan	A orphans	GPR21	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.27	2023-12-27	10.1038/s41467-023-35882-w
8HJ2	A	Orphan	A orphans	GPR21	Homo sapiens	-	-	chim(Gs-CtG15)/&β;1/&γ;2	3.8	2023-03-15	10.1038/s41467-023-35882-w
8HMV	A	Orphan	A orphans	GPR21	Homo sapiens	-	-	Gs/&β;1/&γ;2	2.91	2023-03-01	10.1002/mco2.205
8U8F	A	Orphan	A orphans	GPR3	Homo sapiens	PML	-	Gs/&β;1/&γ;2	3.49	2024-03-06	10.1021/acs.biochem.3c00647
8WW2	A	Orphan	A orphans	GPR3	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.79	2024-02-14	10.1038/s41422-024-00932-5
8X2K	A	Orphan	A orphans	GPR3	Homo sapiens	5YM	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.03	2024-04-03	To be published
8IYX	A	Orphan	A orphans	GPR34	Homo sapiens	YL-365	-	-	3.34	2024-03-20	10.1073/pnas.2308435120
8IZ4	A	Orphan	A orphans	GPR34	Homo sapiens	Lysophosphatidylserine	-	Gi1/&β;1/&γ;2	2.94	2024-04-10	To be published
8K4N	A	Orphan	A orphans	GPR34	Homo sapiens	VF0	-	Gi1/&β;1/&γ;2	2.83	2023-10-25	To be published
8SAI	A	Orphan	A orphans	GPR34	Homo sapiens	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	-	Gi1/&β;1/&γ;2	3.27	2023-10-04	10.1073/pnas.2308435120
8WRB	A	Orphan	A orphans	GPR34	Homo sapiens	Lysophosphatidylserine	-	Gi1/&β;1/&γ;2	2.91	2023-11-08	10.1371/journal.pbio.3002387
8XBH	A	Orphan	A orphans	GPR34	Homo sapiens	S3E-LysoPS	-	Gi1/&β;1/&γ;2	2.83	2023-12-27	To be published
8XBI	A	Orphan	A orphans	GPR34	Homo sapiens	S3E-LysoPS	-	-	3.06	2023-12-27	To be published
8H8J	A	Orphan	A orphans	GPR35	Homo sapiens	Lodoxamide	Ca	chim(NtGi1L-G13)/&β;1/&γ;2	3.2	2023-02-08	10.1038/s41421-022-00499-8
6LI0	A	Orphan	A orphans	GPR52	Homo sapiens	-	GTPL9804	-	2.2	2020-02-26	10.1038/s41586-020-2019-0
6LI1	A	Orphan	A orphans	GPR52	Homo sapiens	-	-	-	2.9	2020-02-26	10.1038/s41586-020-2019-0
6LI2	A	Orphan	A orphans	GPR52	Homo sapiens	-	-	-	2.8	2020-02-26	10.1038/s41586-020-2019-0
6LI3	A	Orphan	A orphans	GPR52	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.32	2020-02-26	10.1038/s41586-020-2019-0
8HMP	A	Orphan	A orphans	GPR52	Homo sapiens	-	PubChem 69921479	Gs/&β;1/&γ;2	2.77	2023-06-21	10.1002/mco2.260
8KGK	A	Orphan	A orphans	GPR61	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.16	2023-10-11	10.1038/s41467-023-41654-3
8TB0	A	Orphan	A orphans	GPR61	Homo sapiens	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.47	2023-10-04	10.1038/s41467-023-41646-3
8TB7	A	Orphan	A orphans	GPR61	Homo sapiens	-	PubChem 168510218	-	2.94	2023-10-04	10.1038/s41467-023-41646-3
8G05	A	Orphan	A orphans	GPR84	Homo sapiens	6-OAU	-	Gi1/&β;1/&γ;2	3	2023-11-01	10.1038/s41467-023-41201-0
8J18	A	Orphan	A orphans	GPR84	Homo sapiens	(3R)-3-hydroxydodecanoic acid	-	Gi1/&β;1/&γ;2	2.89	2023-06-21	10.1038/s41467-023-38985-6
8J19	A	Orphan	A orphans	GPR84	Homo sapiens	PubChem 127045422	-	Gi1/&β;1/&γ;2	3.23	2023-06-21	10.1038/s41467-023-38985-6
8J1A	A	Orphan	A orphans	GPR84	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.24	2023-06-21	10.1038/s41467-023-38985-6
7EJX	A	Orphan	A orphans	GPR88	Homo sapiens	-	(1R;2R)-2-PCCA	Gi1/&β;1/&γ;2	2.4	2022-04-13	10.1038/s41467-022-30081-5
7WZ4	A	Orphan	A orphans	GPR88	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3	2022-10-26	10.1038/s41467-022-30081-5
3RZE	A	Amine	Histamine	H₁	Homo sapiens	Cidoxepin	-	-	3.1	2011-06-15	10.1038/nature10236
7DFL	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-	chim(NtGi1L-Gq)/&β;1/&γ;2	3.3	2021-03-31	10.1038/s41467-021-22427-2
8X5X	A	Amine	Histamine	H₁	Homo sapiens	-	-	-	3.5	2024-01-17	10.1038/s41467-023-44477-4
8X5Y	A	Amine	Histamine	H₁	Homo sapiens	Astemizole	-	-	3	2024-01-17	10.1038/s41467-023-44477-4
8X63	A	Amine	Histamine	H₁	Homo sapiens	Mepyramine	-	-	3.2	2024-01-17	10.1038/s41467-023-44477-4
8X64	A	Amine	Histamine	H₁	Homo sapiens	Desloratadine	-	-	3.4	2024-01-17	10.1038/s41467-023-44477-4
8POK	A	Amine	Histamine	H₂	Homo sapiens	Histamine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41467-024-46096-z
7F61	A	Amine	Histamine	H₃	Homo sapiens	PF-03654746	Cholesterol	-	2.6	2022-10-26	10.1038/s41467-022-33880-y
7YFC	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3	2023-10-25	10.1038/s41467-023-42260-z
7YFD	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.1	2023-10-25	10.1038/s41467-023-42260-z
8HN8	A	Amine	Histamine	H₄	Homo sapiens	Histamine	-	Gi1/&β;1/&γ;2	3	2023-12-20	To be published
8HOC	A	Amine	Histamine	H₄	Homo sapiens	Imetit	-	Gi1/&β;1/&γ;2	3	2023-12-20	To be published
8JXT	A	Amine	Histamine	H₄	Homo sapiens	Histamine	PO4	Gi1/&β;1/&γ;2	3.07	2024-03-20	10.1038/s41467-024-46840-5
8JXV	A	Amine	Histamine	H₄	Homo sapiens	Clozapine	-	Gi1/&β;1/&γ;2	3.21	2024-03-20	10.1038/s41467-024-46840-5
8JXW	A	Amine	Histamine	H₄	Homo sapiens	VUF6884	-	Gi1/&β;1/&γ;2	3.01	2024-03-20	10.1038/s41467-024-46840-5
8JXX	A	Amine	Histamine	H₄	Homo sapiens	Clobenpropit	-	Gi1/&β;1/&γ;2	3.06	2024-03-20	10.1038/s41467-024-46840-5
7XK2	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK6892	-	Gi1/&β;1/&γ;2	3.1	2023-02-22	10.1038/s41467-023-37177-6
7ZL9	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	10.1038/s41467-023-37177-6
7ZLY	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	-	-	-	2.7	2023-04-12	10.1038/s41467-023-37177-6
8H2G	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/&β;1/&γ;2	3.01	2023-10-11	To be published
8I7V	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/&β;1/&γ;2	2.77	2024-02-07	10.1038/s41467-023-42764-8
8I7W	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/&β;1/&γ;2	3.39	2024-02-07	10.1038/s41467-023-42764-8
8IHB	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/&β;1/&γ;2	2.85	2023-09-13	10.1038/s41467-023-41650-7
8IHF	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK6892	-	Gi1/&β;1/&γ;2	2.97	2023-08-30	10.1038/s41467-023-41650-7
8IHH	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	LUF6283	-	Gi1/&β;1/&γ;2	3.06	2023-08-30	10.1038/s41467-023-41650-7
8IHI	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Acifran	-	Gi1/&β;1/&γ;2	3.11	2023-08-30	10.1038/s41467-023-41650-7
8IJ3	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.28	2024-01-03	10.1038/s41421-023-00610-7
8IJA	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/&β;1/&γ;2	2.69	2024-01-03	10.1038/s41421-023-00610-7
8IJB	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Acipimox	-	Gi1/&β;1/&γ;2	3.23	2024-01-03	10.1038/s41421-023-00610-7
8IJD	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK6892	-	Gi1/&β;1/&γ;2	3.25	2024-01-03	10.1038/s41421-023-00610-7
8IY9	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Go/&β;1/&γ;2	3.37	2024-03-06	10.1038/s41467-024-46239-2
8IYH	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK6892	-	Go/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41467-024-46239-2
8IYW	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	GSK256073	-	Go/&β;1/&γ;2	3.45	2024-03-06	10.1038/s41467-024-46239-2
8J6I	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK6892	-	Gi1/&β;1/&γ;2	2.92	2024-04-03	10.1016/j.celrep.2023.113406
8J6J	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	GSK256073	-	Gi1/&β;1/&γ;2	2.8	2024-01-10	10.1016/j.celrep.2023.113406
8J6L	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/&β;1/&γ;2	3.05	2024-04-03	10.1016/j.celrep.2023.113406
8J6P	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/&β;1/&γ;2	2.55	2023-12-06	10.1038/s41467-023-43537-z
8J6Q	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Beta-hydroxybutyrate	Compound 9n	Gi1/&β;1/&γ;2	2.6	2023-12-06	10.1038/s41467-023-43537-z
8J6R	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK6892	-	Gi1/&β;1/&γ;2	2.76	2023-12-06	10.1038/s41467-023-43537-z
8JER	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Acipimox	-	Go/&β;1/&γ;2	3.45	2024-03-06	10.1038/s41467-024-46239-2
8JHN	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MMF	-	Go/&β;1/&γ;2	3.75	2024-03-06	10.1038/s41467-024-46239-2
8JHY	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	-	Compound 9n	Gi1/&β;1/&γ;2	2.87	2023-09-06	10.1016/j.molcel.2023.07.030
8JII	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	Compound 9n	Gi1/&β;1/&γ;2	3.17	2023-09-06	10.1016/j.molcel.2023.07.030
8JIL	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	Gi1/&β;1/&γ;2	3.5	2023-09-06	10.1016/j.molcel.2023.07.030
8JIM	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MMF	-	Gi1/&β;1/&γ;2	2.98	2023-09-06	10.1016/j.molcel.2023.07.030
8JZ7	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	MK6892	-	Gi1/&β;1/&γ;2	2.6	2023-10-04	10.1038/s41392-023-01625-y
8K5B	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Niacin	-	-	3.43	2023-11-22	10.1038/s41467-023-42764-8
8K5C	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	Acipimox	-	-	3.13	2023-11-22	10.1038/s41467-023-42764-8
8K5D	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₂	Homo sapiens	GSK256073	-	-	3.74	2023-11-22	10.1038/s41467-023-42764-8
8IHJ	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₃	Homo sapiens	Acifran	-	Gi1/&β;1/&γ;2	3.07	2023-08-30	10.1038/s41467-023-41650-7
8IHK	A	Alicarboxylic acid	Hydroxycarboxylic acid	HCA₃	Homo sapiens	Acifran	-	-	3.21	2023-08-30	10.1038/s41467-023-41650-7
8X79	A	Lipid	Prostanoid	I2	Homo sapiens	MRE-269	-	Gs/&β;1/&γ;2	2.41	2024-03-06	10.1126/sciadv.adk5184
8X7A	A	Lipid	Prostanoid	I2	Homo sapiens	Treprostinil	-	Gs/&β;1/&γ;2	2.56	2024-03-06	10.1126/sciadv.adk5184
4DJH	A	Peptide	Opioid	κ	Homo sapiens	JDTic	-	-	2.9	2012-03-21	10.1038/nature10939
6B73	A	Peptide	Opioid	κ	Homo sapiens	PubChem 131955138	-	-	3.1	2018-01-17	10.1016/j.cell.2017.12.011
6VI4	A	Peptide	Opioid	κ	Homo sapiens	JDTic	-	-	3.3	2020-03-18	10.1038/s41467-020-14889-7
7Y1F	A	Peptide	Opioid	κ	Homo sapiens	Dynorphin	-	Gi1/&β;1/&γ;2	3.3	2023-05-24	10.1093/procel/pwac033
7YIT	A	Peptide	Opioid	κ	Homo sapiens	Nalfurafine	-	-	3.3	2023-04-12	10.1038/s41467-023-37041-7
8DZP	A	Peptide	Opioid	κ	Homo sapiens	momSalB	-	Gi1/&β;1/&γ;2	2.71	2023-05-03	10.1038/s41586-023-06030-7
8DZQ	A	Peptide	Opioid	κ	Homo sapiens	momSalB	-	Go/&β;1/&γ;2	2.82	2023-05-03	10.1038/s41586-023-06030-7
8DZR	A	Peptide	Opioid	κ	Homo sapiens	GR89,696	-	chim(NtGi2-Gt3)/&β;1/&γ;2	2.61	2023-05-03	10.1038/s41586-023-06030-7
8DZS	A	Peptide	Opioid	κ	Homo sapiens	GR89,696	-	chim(NtGi2-Gz)/&β;1/&γ;2	2.65	2023-05-03	10.1038/s41586-023-06030-7
8F7W	A	Peptide	Opioid	κ	Homo sapiens	Dynorphin	-	Gi1/&β;1/&γ;2	3.19	2022-12-14	10.1016/j.cell.2022.12.026
8FEG	A	Peptide	Opioid	κ	Homo sapiens	PRD_002517	-	Gi1/&β;1/&γ;2	2.54	2023-12-06	10.1038/s41467-023-43718-w
7FIG	A	Protein	Glycoprotein hormone	LH	Homo sapiens	hCG	-	chim(NtGi1L-Gs)/&β;1/&γ;2	3.9	2021-09-29	10.1038/s41586-021-03924-2
7FIH	A	Protein	Glycoprotein hormone	LH	Homo sapiens	hCG	Org43553	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2021-09-29	10.1038/s41586-021-03924-2
7FII	A	Protein	Glycoprotein hormone	LH	Homo sapiens	hCG	-	6fuf	4.3	2021-09-29	10.1038/s41586-021-03924-2
7FIJ	A	Protein	Glycoprotein hormone	LH	Homo sapiens	-	-	-	3.8	2021-09-29	10.1038/s41586-021-03924-2
4Z34	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-9780307	-	-	3	2015-06-03	10.1016/j.cell.2015.06.002
4Z35	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-9910539	-	-	2.9	2015-06-03	10.1016/j.cell.2015.06.002
4Z36	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-3080573	-	-	2.9	2015-06-03	10.1016/j.cell.2015.06.002
7TD0	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	LPA	-	Gi1/&β;1/&γ;2	2.83	2022-02-09	10.1038/s41467-022-28417-2
7TD1	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	LPA	-	Gi1/&β;1/&γ;2	3.08	2022-02-09	10.1038/s41467-022-28417-2
7TD2	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	LPA	-	Gi1/&β;1/&γ;2	3.11	2022-02-09	10.1038/s41467-022-28417-2
7YU3	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/&β;1/&γ;2	3.5	2022-10-05	10.1038/s41467-022-33121-2
7YU4	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-0740556	-	-	3.7	2022-10-05	10.1038/s41467-022-33121-2
7YU5	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/&β;1/&γ;2	3.7	2022-10-05	10.1038/s41467-022-33121-2
7YU6	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/&β;1/&γ;2	3.9	2022-10-05	10.1038/s41467-022-33121-2
7YU7	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/&β;1/&γ;2	4.5	2022-10-05	10.1038/s41467-022-33121-2
7YU8	A	Lipid	Lysophospholipid (LPA)	LPA₁	Homo sapiens	ONO-0740556	-	Gi1/&β;1/&γ;2	5.6	2022-10-05	10.1038/s41467-022-33121-2
5XSZ	A	Lipid	Lysophospholipid (LPA)	LPA₆	Danio rerio	Glyceryl Mono-oleate	-	-	3.2	2017-08-16	10.1038/nature23448
5CXV	A	Amine	Acetylcholine (muscarinic)	M₁	Homo sapiens	Tiotropium	-	-	2.7	2016-03-09	10.1038/nature17188
6OIJ	A	Amine	Acetylcholine (muscarinic)	M₁	Homo sapiens	Iperoxo	-	chim(NtGi1L-G11)/&β;1/&γ;2	3.3	2019-05-08	10.1126/science.aaw5188
6WJC	A	Amine	Acetylcholine (muscarinic)	M₁	Homo sapiens	Atropine	Muscarinic toxin 7	-	2.55	2020-07-08	10.1126/science.aax2517
6ZFZ	A	Amine	Acetylcholine (muscarinic)	M₁	Homo sapiens	77-LH-28-1	-	-	2.17	2021-10-06	10.1016/j.cell.2021.11.001
6ZG4	A	Amine	Acetylcholine (muscarinic)	M₁	Homo sapiens	HTL0009936	-	-	2.33	2021-10-06	10.1016/j.cell.2021.11.001
6ZG9	A	Amine	Acetylcholine (muscarinic)	M₁	Homo sapiens	GSK1034702	-	-	2.5	2021-10-06	10.1016/j.cell.2021.11.001
3UON	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Quinuclidinyl benzilate hydrobromide	-	-	3	2012-02-01	10.1038/nature10753
4MQS	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Iperoxo	-	-	3.5	2013-11-27	10.1038/nature12735
4MQT	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Iperoxo	LY2119620	-	3.7	2013-11-27	10.1038/nature12735
5YC8	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	N-Methyl Scopolamine	-	-	2.5	2018-11-21	10.1038/s41589-018-0152-y
5ZK3	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Quinuclidinyl benzilate hydrobromide	-	-	2.6	2018-11-21	10.1038/s41589-018-0152-y
5ZK8	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	N-Methyl Scopolamine	-	-	3	2018-11-21	10.1038/s41589-018-0152-y
5ZKB	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	AF-DX 384	-	-	2.95	2018-11-21	10.1038/s41589-018-0152-y
5ZKC	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	N-Methyl Scopolamine	-	-	2.3	2018-11-21	10.1038/s41589-018-0152-y
6OIK	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Iperoxo	LY2119620	chim(NtGi1-Go)/&β;1/&γ;2	3.6	2019-05-08	10.1126/science.aaw5188
6U1N	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	-	LY2119620	Arrestin2	4	2020-02-26	10.1038/s41586-020-1954-0
7T8X	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Acetylcholine	-	chim(NtGi1-Go)/&β;1/&γ;2	3.21	2023-01-25	10.1038/s41467-022-35726-z
7T90	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Acetylcholine	-	chim(NtGi1-Go)/&β;1/&γ;2	3.32	2023-01-25	10.1038/s41467-022-35726-z
7T94	A	Amine	Acetylcholine (muscarinic)	M₂	Homo sapiens	Acetylcholine	PubChem 57664406	chim(NtGi1-Go)/&β;1/&γ;2	3.16	2023-01-25	10.1038/s41467-022-35726-z
4DAJ	A	Amine	Acetylcholine (muscarinic)	M₃	Rattus norvegicus	Tiotropium	-	-	3.4	2012-02-22	10.1038/nature10867
4U14	A	Amine	Acetylcholine (muscarinic)	M₃	Rattus norvegicus	Tiotropium	-	-	3.57	2014-11-26	10.1016/j.str.2014.08.022
4U15	A	Amine	Acetylcholine (muscarinic)	M₃	Rattus norvegicus	Tiotropium	-	-	2.8	2014-11-26	10.1016/j.str.2014.08.022
4U16	A	Amine	Acetylcholine (muscarinic)	M₃	Rattus norvegicus	N-Methyl Scopolamine	-	-	3.7	2014-11-26	10.1016/j.str.2014.08.022
5ZHP	A	Amine	Acetylcholine (muscarinic)	M₃	Rattus norvegicus	PubChem 134828589	-	-	3.1	2018-11-28	10.1073/pnas.1813988115
8E9W	A	Amine	Acetylcholine (muscarinic)	M₃	Homo sapiens	2-Deoxycytidine	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.69	2022-11-30	10.1038/s41586-022-05489-0
8E9Y	A	Amine	Acetylcholine (muscarinic)	M₃	Homo sapiens	PubChem 446603	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.79	2022-11-30	10.1038/s41586-022-05489-0
8E9Z	A	Amine	Acetylcholine (muscarinic)	M₃	Homo sapiens	Iperoxo	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.69	2022-11-30	10.1038/s41586-022-05489-0
8EA0	A	Amine	Acetylcholine (muscarinic)	M₃	Homo sapiens	Iperoxo	-	-	2.56	2022-11-30	10.1038/s41586-022-05489-0
5DSG	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Tiotropium	-	-	2.6	2016-03-16	10.1038/nature17188
6KP6	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	-	-	-	3	2020-03-11	10.1107/S2052252520000597
7TRK	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	-	Gi1/&β;1/&γ;2	2.8	2023-05-17	10.2139/ssrn.4034884
7TRP	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	LY2033298	Gi1/&β;1/&γ;2	2.4	2023-05-17	10.2139/ssrn.4034884
7TRQ	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	VU0467154	Gi1/&β;1/&γ;2	2.5	2023-05-17	10.2139/ssrn.4034884
7TRS	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Acetylcholine	-	Gi1/&β;1/&γ;2	2.8	2023-05-17	10.2139/ssrn.4034884
7V68	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Iperoxo	PubChem 57664406	Gi1/&β;1/&γ;2	3.4	2022-05-11	10.1038/s41467-022-30595-y
7V69	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	-	-	Gi1/&β;1/&γ;2	3.4	2022-05-11	10.1038/s41467-022-30595-y
7V6A	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	PubChem 9864275	-	Gi1/&β;1/&γ;2	3.6	2022-05-11	10.1038/s41467-022-30595-y
8E9X	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	2-Deoxycytidine	-	chim(NtGi1-Go)/&β;1/&γ;2	2.7	2022-11-30	10.1038/s41586-022-05489-0
8FX5	A	Amine	Acetylcholine (muscarinic)	M₄	Homo sapiens	Xanomeline	Xanomeline	Gi1/&β;1/&γ;2	2.45	2023-09-13	10.1038/s41467-023-41199-5
6OL9	A	Amine	Acetylcholine (muscarinic)	M₅	Homo sapiens	Tiotropium	-	-	2.54	2019-12-11	10.1073/pnas.1914446116
7F4D	A	Peptide	Melanocortin	MC₁	Homo sapiens	Alpha-MSH	-	chim(NtGi1-Gs)/&β;1/&γ;2	3	2021-09-08	10.1038/s41422-021-00557-y
7F4F	A	Peptide	Melanocortin	MC₁	Homo sapiens	Afamelanotide	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2021-09-08	10.1038/s41422-021-00557-y
7F4H	A	Peptide	Melanocortin	MC₁	Homo sapiens	Afamelanotide	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.7	2021-09-08	10.1038/s41422-021-00557-y
7F4I	A	Peptide	Melanocortin	MC₁	Homo sapiens	SHU9119	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2021-09-08	10.1038/s41422-021-00557-y
8GY7	A	Peptide	Melanocortin	MC₂	Homo sapiens	Corticotropin	Ca	chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1	3.3	2023-01-11	10.1038/s41422-022-00751-6
8IOC	A	Peptide	Melanocortin	MC₃	Homo sapiens	Gamma-MSH	Ca	chim(NtGi1-Gs)/&β;1/&γ;2	2.86	2023-09-20	10.1038/s41421-023-00586-4
6W25	A	Peptide	Melanocortin	MC₄	Homo sapiens	SHU9119	Ca	-	2.75	2020-04-29	10.1126/science.aaz8995
7AUE	A	Peptide	Melanocortin	MC₄	Homo sapiens	Setmelanotide	-	chim(NtGi1L-Gs)/&β;1/&γ;2	2.97	2021-04-28	10.1126/science.abf7958
7F53	A	Peptide	Melanocortin	MC₄	Homo sapiens	Alpha-MSH	-	Gs/&β;1/&γ;2	3	2021-11-03	10.1038/s41422-021-00552-3
7F54	A	Peptide	Melanocortin	MC₄	Homo sapiens	Afamelanotide	-	Gs/&β;1/&γ;2	3	2021-11-03	10.1038/s41422-021-00552-3
7F55	A	Peptide	Melanocortin	MC₄	Homo sapiens	Bremelanotide	-	Gs/&β;1/&γ;2	3.1	2021-11-03	10.1038/s41422-021-00552-3
7F58	A	Peptide	Melanocortin	MC₄	Homo sapiens	THIQ	-	Gs/&β;1/&γ;2	3.1	2021-11-03	10.1038/s41422-021-00552-3
7PIU	A	Peptide	Melanocortin	MC₄	Homo sapiens	Setmelanotide	-	Gs/&β;1/&γ;2	2.58	2021-11-17	10.1038/s41422-021-00569-8
7PIV	A	Peptide	Melanocortin	MC₄	Homo sapiens	Setmelanotide	-	Gs/&β;1/&γ;2	2.86	2021-11-17	10.1038/s41422-021-00569-8
8INR	A	Peptide	Melanocortin	MC₅	Homo sapiens	Alpha-MSH	Ca	chim(NtGi1-Gs)/&β;1/&γ;2	2.73	2023-09-20	10.1038/s41421-023-00586-4
8IOD	A	Peptide	Melanocortin	MC₅	Homo sapiens	PG-901	Ca	chim(NtGi1-Gs)/&β;1/&γ;2	2.59	2023-09-20	10.1038/s41421-023-00586-4
7EPE	C	Aminoacid	Metabotropic glutamate	mGlu	Homo sapiens	-	NAM563	-	2.5	2021-06-23	10.1038/s41586-021-03641-w
4OR2	C	Aminoacid	Metabotropic glutamate	mGlu1; mGlu1	Homo sapiens	-	FITM	-	2.8	2014-03-19	10.1126/science.1249489
7DGD	C	Aminoacid	Metabotropic glutamate	mGlu1; mGlu1	Homo sapiens	-	-	-	3.96	2021-09-22	10.1007/s13238-020-00808-5
7DGE	C	Aminoacid	Metabotropic glutamate	mGlu1; mGlu1	Homo sapiens	Quisqualate	-	-	3.65	2021-09-22	10.1007/s13238-020-00808-5
7E9G	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	JNJ-40411813	Gi1/&β;1/&γ;2	3.5	2021-06-23	10.1038/s41586-021-03495-2
7EPA	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu2	Homo sapiens	-	-	-	3.6	2021-06-23	10.1038/s41586-021-03641-w
7EPB	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu2	Homo sapiens	Eglumetad	-	-	3.1	2021-06-23	10.1038/s41586-021-03641-w
7EPF	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu2	Homo sapiens	-	NAM597	-	2.7	2021-06-23	10.1038/s41586-021-03641-w
7MTQ	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu2	Homo sapiens	LY341495	-	-	3.65	2021-07-07	10.1038/s41586-021-03680-3
7MTR	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164	-	3.3	2021-07-07	10.1038/s41586-021-03680-3
7MTS	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu2	Homo sapiens	Glutamate	ADX55164	Gi1/&β;1/&γ;2	3.2	2021-07-07	10.1038/s41586-021-03680-3
8JCU	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	2.8	2023-06-21	10.1038/s41422-023-00830-2
8JCV	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3.4	2023-06-21	10.1038/s41422-023-00830-2
8JCW	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	10.1038/s41422-023-00830-2
8JCX	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	10.1038/s41422-023-00830-2
8JCY	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	2.9	2023-06-21	10.1038/s41422-023-00830-2
8JCZ	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	LY341495	-	-	3	2023-06-21	10.1038/s41422-023-00830-2
8JD0	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	J9R	-	3.3	2023-06-21	10.1038/s41422-023-00830-2
8JD1	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	-	-	3.7	2023-06-21	10.1038/s41422-023-00830-2
8JD2	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	-	-	2.8	2023-06-21	10.1038/s41422-023-00830-2
8JD3	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	HZR; PEF	Gi1/&β;1/&γ;2	3.3	2023-06-21	10.1038/s41422-023-00830-2
8JD4	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	-	-	2.9	2023-06-21	10.1038/s41422-023-00830-2
8JD5	C	Aminoacid	Metabotropic glutamate	mGlu2; mGlu4	Homo sapiens	Glutamate	BQI; HZE; PEF	Gi1/&β;1/&γ;2	3.6	2023-06-21	10.1038/s41422-023-00830-2
7EPD	C	Aminoacid	Metabotropic glutamate	mGlu₂, mGlu₇	Homo sapiens	-	-	-	3.9	2021-06-23	10.1038/s41586-021-03641-w
7WI6	C	Aminoacid	Metabotropic glutamate	mGlu3; mGlu3	Homo sapiens	LY341495	-	-	3.71	2022-03-16	10.1038/s41422-022-00623-z
7WI8	C	Aminoacid	Metabotropic glutamate	mGlu3; mGlu3	Homo sapiens	LY341495	-	-	4.17	2022-03-16	10.1038/s41422-022-00623-z
7WIH	C	Aminoacid	Metabotropic glutamate	mGlu3; mGlu3	Homo sapiens	LY2794193	-	-	3.68	2022-03-16	10.1038/s41422-022-00623-z
7E9H	C	Aminoacid	Metabotropic glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	-	Gi3/&β;1/&γ;2	4	2021-06-23	10.1038/s41586-021-03495-2
8JD6	C	Aminoacid	Metabotropic glutamate	mGlu4; mGlu4	Homo sapiens	Phosphoserine	N-(3-chlorophenyl)pyridine-2-carboxamide	Gi3/&β;1/&γ;2	3.4	2023-06-21	10.1038/s41422-023-00830-2
4OO9	C	Aminoacid	Metabotropic glutamate	mGlu₅	Homo sapiens	-	Mavoglurant	-	2.6	2014-07-02	10.1038/nature13396
5CGC	C	Aminoacid	Metabotropic glutamate	mGlu₅	Homo sapiens	-	HTL14242	-	3.1	2015-08-12	10.1021/acs.jmedchem.5b00892
5CGD	C	Aminoacid	Metabotropic glutamate	mGlu₅	Homo sapiens	-	HTL14242	-	2.6	2015-08-12	10.1021/acs.jmedchem.5b00892
6FFH	C	Aminoacid	Metabotropic glutamate	mGlu₅	Homo sapiens	-	Fenobam	-	2.65	2018-03-07	10.1021/acs.jmedchem.7b01722
6FFI	C	Aminoacid	Metabotropic glutamate	mGlu₅	Homo sapiens	-	MMPEP	-	2.2	2018-03-07	10.1021/acs.jmedchem.7b01722
7P2L	C	Aminoacid	Metabotropic glutamate	mGlu₅	Homo sapiens	-	4YI	-	2.54	2021-09-08	10.1016/j.celrep.2021.109648
6N51	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	Quisqualate	-	-	4	2019-01-23	10.1038/s41586-019-0881-4
6N52	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	-	-	-	4	2019-01-23	10.1038/s41586-019-0881-4
7FD8	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	Quisqualate	-	-	3.8	2021-09-08	10.1016/j.celrep.2021.109648
7FD9	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	LY341495	-	-	4	2021-09-08	10.1016/j.celrep.2021.109648
8T6J	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	-	CDPPB	-	3.5	2023-10-11	10.1101/2023.08.29.555158
8T7H	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	Quisqualate	-	-	3.3	2023-10-11	10.1101/2023.08.29.555158
8T8M	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	Quisqualate	-	-	3	2023-10-11	10.1101/2023.08.29.555158
8TAO	C	Aminoacid	Metabotropic glutamate	mGlu5; mGlu5	Homo sapiens	Quisqualate	CDPPB	-	2.9	2023-10-11	10.1101/2023.08.29.555158
7EPC	C	Aminoacid	Metabotropic glutamate	mGlu7; mGlu7	Homo sapiens	-	-	-	4	2021-06-23	10.1038/s41586-021-03641-w
4DKL	A	Peptide	Opioid	μ	Mus musculus	Beta-funaltrexamine	-	-	2.8	2012-03-21	10.1038/nature10954
5C1M	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.07	2015-08-05	10.1038/nature14886
6DDE	A	Peptide	Opioid	μ	Mus musculus	Damgo	-	Gi1/&β;1/&γ;2	3.5	2018-06-13	10.1038/s41586-018-0219-7
6DDF	A	Peptide	Opioid	μ	Mus musculus	Damgo	-	Gi1/&β;1/&γ;2	3.5	2018-06-13	10.1038/s41586-018-0219-7
7SBF	A	Peptide	Opioid	μ	Mus musculus	PZM21	-	Gi1/&β;1/&γ;2	2.9	2022-04-20	10.1002/anie.202200269
7SCG	A	Peptide	Opioid	μ	Mus musculus	FH210	-	Gi1/&β;1/&γ;2	3	2022-04-20	10.1002/anie.202200269
7T2G	A	Peptide	Opioid	μ	Mus musculus	Mitragynine pseudoindoxyl	-	Gi1/&β;1/&γ;2	2.5	2022-12-07	10.1038/s41589-022-01208-y
7T2H	A	Peptide	Opioid	μ	Mus musculus	Lofentanil	-	Gi1/&β;1/&γ;2	2.5	2022-12-07	10.1038/s41589-022-01208-y
7U2K	A	Peptide	Opioid	μ	Mus musculus	C6-guano	-	Gi1/&β;1/&γ;2	3.3	2022-12-07	10.1038/s41586-022-05588-y
7U2L	A	Peptide	Opioid	μ	Mus musculus	PubChem 163201242	-	Gi1/&β;1/&γ;2	3.2	2022-05-04	10.1038/s41586-022-05588-y
7UL4	A	Peptide	Opioid	μ	Mus musculus	Alvimopan	-	-	2.8	2022-06-29	10.1038/s41594-022-00859-8
8E0G	A	Peptide	Opioid	μ	Mus musculus	BU72	-	-	2.1	2023-10-18	10.1186/s12915-023-01689-w
8EF5	A	Peptide	Opioid	μ	Homo sapiens	Fentanyl	-	Gi1/&β;1/&γ;2	3.3	2022-11-09	10.1016/j.cell.2022.09.041
8EF6	A	Peptide	Opioid	μ	Homo sapiens	Morphine	-	Gi1/&β;1/&γ;2	3.2	2022-11-09	10.1016/j.cell.2022.09.041
8EFB	A	Peptide	Opioid	μ	Homo sapiens	Oliceridine	-	Gi1/&β;1/&γ;2	3.2	2022-11-09	10.1016/j.cell.2022.09.041
8EFL	A	Peptide	Opioid	μ	Homo sapiens	SR17018	-	Gi1/&β;1/&γ;2	3.2	2022-11-09	10.1016/j.cell.2022.09.041
8EFO	A	Peptide	Opioid	μ	Homo sapiens	PZM21	-	Gi1/&β;1/&γ;2	2.8	2022-11-09	10.1016/j.cell.2022.09.041
8EFQ	A	Peptide	Opioid	μ	Homo sapiens	Damgo	-	Gi1/&β;1/&γ;2	3.3	2022-11-09	10.1016/j.cell.2022.09.041
8F7Q	A	Peptide	Opioid	μ	Homo sapiens	Beta-endorphin	-	Gi1/&β;1/&γ;2	3.22	2022-12-14	10.1016/j.cell.2022.12.026
8F7R	A	Peptide	Opioid	μ	Homo sapiens	Endomorphin	-	Gi1/&β;1/&γ;2	3.28	2022-12-14	10.1016/j.cell.2022.12.026
8QOT	A	Peptide	Opioid	μ	Mus musculus	Nanobody E	-	-	3.2	2023-12-27	10.1101/2023.12.06.570395
8IBU	A	Peptide	Motilin	Motilin	Homo sapiens	Erythromycin A	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.51	2023-04-12	10.1126/sciadv.ade9020
8IBV	A	Peptide	Motilin	Motilin	Homo sapiens	Motilin	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.19	2023-04-12	10.1126/sciadv.ade9020
7Y12	A	Orphan	A orphans	MRGPRD	Homo sapiens	Beta-alanine	-	Gi1/&β;1/&γ;2	3.1	2022-07-20	10.1038/s42003-022-03668-3
7Y13	A	Orphan	A orphans	MRGPRD	Homo sapiens	-	-	-	3.1	2022-07-20	10.1038/s42003-022-03668-3
7Y14	A	Orphan	A orphans	MRGPRD	Homo sapiens	Beta-alanine	-	-	3.2	2022-07-20	10.1038/s42003-022-03668-3
7Y15	A	Orphan	A orphans	MRGPRD	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.9	2022-07-20	10.1038/s42003-022-03668-3
8DWC	A	Orphan	A orphans	MRGPRX1	Homo sapiens	Proenkephalin-A	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.87	2022-11-02	10.1038/s41589-022-01173-6
8DWG	A	Orphan	A orphans	MRGPRX1	Homo sapiens	Proenkephalin-A	ML382	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.71	2022-11-02	10.1038/s41589-022-01173-6
8DWH	A	Orphan	A orphans	MRGPRX1	Homo sapiens	Compound-16	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.25	2022-11-02	10.1038/s41589-022-01173-6
8HJ5	A	Orphan	A orphans	MRGPRX1	Homo sapiens	PubChem 139030531	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3	2023-05-31	10.1371/journal.pbio.3001975
8JGB	A	Orphan	A orphans	MRGPRX1	Homo sapiens	Conorfamide-Tx2	-	Gi1/&β;1/&γ;2	2.84	2024-01-10	10.1038/s41467-023-40705-z
8JGF	A	Orphan	A orphans	MRGPRX1	Homo sapiens	BAM8-22	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.7	2024-01-10	10.1038/s41467-023-40705-z
8JGG	A	Orphan	A orphans	MRGPRX1	Homo sapiens	BAM8-22	-	Gi1/&β;1/&γ;2	3	2024-01-10	10.1038/s41467-023-40705-z
7S8L	A	Orphan	A orphans	MRGPRX2	Homo sapiens	Cortistatin-14	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.45	2021-11-17	10.1038/s41586-021-04126-6
7S8M	A	Orphan	A orphans	MRGPRX2	Homo sapiens	Cortistatin-14	-	Gi1/&β;1/&γ;2	2.54	2021-11-17	10.1038/s41586-021-04126-6
7S8N	A	Orphan	A orphans	MRGPRX2	Homo sapiens	(R)-Zinc-3573	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.9	2021-11-17	10.1038/s41586-021-04126-6
7S8O	A	Orphan	A orphans	MRGPRX2	Homo sapiens	(R)-Zinc-3573	-	Gi1/&β;1/&γ;2	2.58	2021-11-17	10.1038/s41586-021-04126-6
7VDH	A	Orphan	A orphans	MRGPRX2	Homo sapiens	C48/80	-	Gi1/&β;1/&γ;2	2.9	2021-12-01	10.1038/s41586-021-04077-y
7VDL	A	Orphan	A orphans	MRGPRX2	Homo sapiens	Cortistatin-14	-	Gi1/&β;1/&γ;2	3.22	2021-12-01	10.1038/s41586-021-04077-y
7VDM	A	Orphan	A orphans	MRGPRX2	Homo sapiens	Substance P	-	Gi1/&β;1/&γ;2	2.98	2021-12-01	10.1038/s41586-021-04077-y
7VUY	A	Orphan	A orphans	MRGPRX2	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.84	2021-12-01	10.1038/s41586-021-04077-y
7VUZ	A	Orphan	A orphans	MRGPRX2	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.89	2021-12-01	10.1038/s41586-021-04077-y
7VV0	A	Orphan	A orphans	MRGPRX2	Homo sapiens	PAMP-12	-	-	3.5	2021-12-01	10.1038/s41586-021-04077-y
7VV3	A	Orphan	A orphans	MRGPRX2	Homo sapiens	-	-	Gi1/&β;1/&γ;2	2.97	2021-12-01	10.1038/s41586-021-04077-y
7VV4	A	Orphan	A orphans	MRGPRX2	Homo sapiens	Cortistatin-14	-	-	2.97	2021-12-01	10.1038/s41586-021-04077-y
7VV5	A	Orphan	A orphans	MRGPRX2	Homo sapiens	C48/80	-	Gi1/&β;1/&γ;2	2.76	2021-12-01	10.1038/s41586-021-04077-y
7VV6	A	Orphan	A orphans	MRGPRX2	Homo sapiens	C48/80	-	-	3.3	2021-12-01	10.1038/s41586-021-04077-y
7S8P	A	Orphan	A orphans	MRGPRX4	Homo sapiens	MS47134	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.6	2021-11-17	10.1038/s41586-021-04126-6
6ME2	A	Melatonin	Melatonin	MT₁	Homo sapiens	Ramelteon	-	-	2.8	2019-04-24	10.1038/s41586-019-1141-3
6ME3	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Phenylmelatonin	-	-	2.9	2019-04-24	10.1038/s41586-019-1141-3
6ME4	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Iodomelatonin	-	-	3.2	2019-04-24	10.1038/s41586-019-1141-3
6ME5	A	Melatonin	Melatonin	MT₁	Homo sapiens	Agomelatine	-	-	3.2	2019-04-24	10.1038/s41586-019-1141-3
6PS8	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Phenylmelatonin	-	-	3.3	2019-11-13	10.1107/S2052252519013137
7DB6	A	Melatonin	Melatonin	MT₁	Homo sapiens	Ramelteon	-	Gi1/&β;1/&γ;2	3.3	2021-08-18	10.1038/s41594-021-00634-1
7VGY	A	Melatonin	Melatonin	MT₁	Homo sapiens	2-Iodomelatonin	-	Gi1/&β;1/&γ;2	3.1	2022-03-02	10.1038/s41467-022-28111-3
7VGZ	A	Melatonin	Melatonin	MT₁	Homo sapiens	Remalteon	-	Gi1/&β;1/&γ;2	3.3	2022-03-02	10.1038/s41467-022-28111-3
6ME6	A	Melatonin	Melatonin	MT₂	Homo sapiens	2-Phenylmelatonin	-	-	2.8	2019-04-24	10.1038/s41586-019-1144-0
6ME7	A	Melatonin	Melatonin	MT₂	Homo sapiens	2-Phenylmelatonin	-	-	3.2	2019-04-24	10.1038/s41586-019-1144-0
6ME8	A	Melatonin	Melatonin	MT₂	Homo sapiens	2-Phenylmelatonin	-	-	3.1	2019-04-24	10.1038/s41586-019-1144-0
6ME9	A	Melatonin	Melatonin	MT₂	Homo sapiens	Ramelteon	-	-	3.3	2019-04-24	10.1038/s41586-019-1144-0
7VH0	A	Melatonin	Melatonin	MT₂	Homo sapiens	Ramelteon	-	Gi1/&β;1/&γ;1	3.46	2022-03-02	10.1038/s41467-022-28111-3
6E59	A	Peptide	Tachykinin	NK₁	Homo sapiens	L-760735	-	-	3.4	2018-12-12	10.1073/pnas.1812717115
6HLL	A	Peptide	Tachykinin	NK₁	Homo sapiens	CP99994	-	-	3.27	2019-01-16	10.1038/s41467-018-07939-8
6HLO	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	2.4	2019-01-16	10.1038/s41467-018-07939-8
6HLP	A	Peptide	Tachykinin	NK₁	Homo sapiens	Netupitant	-	-	2.2	2019-01-16	10.1038/s41467-018-07939-8
6J20	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	2.7	2019-03-06	10.1038/s41467-019-08568-5
6J21	A	Peptide	Tachykinin	NK₁	Homo sapiens	Aprepitant	-	-	3.2	2019-03-06	10.1038/s41467-019-08568-5
7P00	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance P	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.71	2021-12-15	10.1126/sciadv.abk2872
7P02	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.87	2021-12-15	10.1126/sciadv.abk2872
7RMG	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance P	-	chim(Gs-CtGq)/&β;1/&γ;2	3	2021-11-03	10.1038/s41589-021-00890-8
7RMH	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance P	-	Gs/&β;1/&γ;2	3.1	2021-11-03	10.1038/s41589-021-00890-8
7RMI	A	Peptide	Tachykinin	NK₁	Homo sapiens	Substance P	-	chim(Gs-CtGq)/&β;1/&γ;2	3.2	2021-11-03	10.1038/s41589-021-00890-8
8U26	A	Peptide	Tachykinin	NK₁	Homo sapiens	Protachykinin-1	-	Gs/&β;1/&γ;2	2.5	2023-11-15	10.1038/s41592-023-02082-9
7XWO	A	Peptide	Tachykinin	NK₂	Homo sapiens	Neurokinin-A	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.7	2023-05-31	10.1038/s41421-022-00437-8
8JBF	A	Peptide	Tachykinin	NK₃	Homo sapiens	Senktide	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3	2024-02-28	10.1038/s41421-023-00564-w
7W53	A	Peptide	Neuromedin U	NMUR1	Homo sapiens	Neuromedin-U-25	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.2	2022-04-20	10.1038/s41467-022-29683-w
7W56	A	Peptide	Neuromedin U	NMUR1	Homo sapiens	Neuromedin-S	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.9	2022-04-20	10.1038/s41467-022-29683-w
7W55	A	Peptide	Neuromedin U	NMUR2	Homo sapiens	Neuromedin-U-25	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	2.8	2022-04-20	10.1038/s41467-022-29683-w
7W57	A	Peptide	Neuromedin U	NMUR2	Homo sapiens	Neuromedin-S	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.2	2022-04-20	10.1038/s41467-022-29683-w
7XK8	A	Peptide	Neuromedin U	NMUR2	Homo sapiens	Neuromedin-U-25	-	Gi1/&β;1/&γ;2	3.3	2023-02-22	10.1038/s41467-022-34814-4
4EA3	A	Peptide	Opioid	NOP	Homo sapiens	PubChem 10296561	-	-	3.01	2012-04-25	10.1038/nature11085
5DHG	A	Peptide	Opioid	NOP	Homo sapiens	PubChem 25001412	-	-	3	2015-10-21	10.1016/j.str.2015.07.024
5DHH	A	Peptide	Opioid	NOP	Homo sapiens	SB-612111	-	-	3	2015-10-21	10.1016/j.str.2015.07.024
8F7X	A	Peptide	Opioid	NOP	Homo sapiens	Nociceptin	-	Gi1/&β;1/&γ;2	3.28	2022-12-14	10.1016/j.cell.2022.12.026
3ZEV	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3	2014-01-29	10.1073/pnas.1317903111
4BUO	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	2.75	2014-01-29	10.1073/pnas.1317903111
4BV0	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3.1	2014-01-29	10.1073/pnas.1317903111
4BWB	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3.57	2014-01-29	10.1073/pnas.1317903111
4GRV	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin 8-13	-	-	2.8	2012-10-17	10.1038/nature11558
4XEE	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	2.9	2015-07-29	10.1038/ncomms8895
4XES	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	2.6	2015-07-29	10.1038/ncomms8895
5T04	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	-	3.3	2016-12-21	10.1038/srep38564
6OS9	A	Peptide	Neurotensin	NTS₁	Homo sapiens	JMV449	-	Gi1/&β;1/&γ;2	3	2019-07-10	10.1038/s41586-019-1337-6
6OSA	A	Peptide	Neurotensin	NTS₁	Homo sapiens	JMV449	-	Gi1/&β;1/&γ;2	3	2019-07-10	10.1038/s41586-019-1337-6
6PWC	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin	-	Arrestin2	4.9	2019-12-04	10.1038/s41422-019-0256-2
6UP7	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin	-	Arrestin2	4.2	2020-02-26	10.1038/s41586-020-1953-1
6YVR	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	NTS8-13	-	-	2.46	2021-02-10	10.1126/sciadv.abe5504
6Z4Q	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SR142948A	-	-	2.92	2021-02-10	10.1126/sciadv.abe5504
6Z4S	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SR48692	-	-	2.71	2021-02-10	10.1126/sciadv.abe5504
6Z4V	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	NTS8-13	-	-	2.6	2021-02-10	10.1126/sciadv.abe5504
6Z66	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	-	-	-	3.19	2021-02-10	10.1126/sciadv.abe5504
6Z8N	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SRI-9829	-	-	2.8	2021-02-10	10.1126/sciadv.abe5504
6ZA8	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	RTI-3a	-	-	2.72	2021-02-10	10.1126/sciadv.abe5504
6ZIN	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	SR48692	-	-	2.64	2021-02-10	10.1126/sciadv.abe5504
7L0P	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/&β;1/&γ;1	4.1	2021-01-06	10.1038/s41594-020-00554-6
7L0Q	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/&β;1/&γ;1	4.3	2021-01-06	10.1038/s41594-020-00554-6
7L0R	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/&β;1/&γ;1	4.2	2021-01-06	10.1038/s41594-020-00554-6
7L0S	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin	-	Gi1/&β;1/γ1	4.5	2021-01-06	10.1038/s41594-020-00554-6
7UL2	A	Peptide	Neurotensin	NTS₁	Homo sapiens	SR48692	Na	-	2.4	2022-06-29	10.1038/s41594-022-00859-8
8FMZ	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/neuromedin N	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.59	2023-03-29	10.1021/acs.biochem.3c00029
8FN0	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/neuromedin N	PubChem 118610427	chim(NtGi1-Go)/&β;1/&γ;2	2.89	2023-03-29	10.1021/acs.biochem.3c00029
8FN1	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	Neurotensin/neuromedin N	-	chim(NtGi1-Go)/&β;1/&γ;2	2.88	2023-03-29	10.1021/acs.biochem.3c00029
8JPB	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin 8-13	PubChem 118610427; GDP; Mg	Gq; GRK2	3.07	2023-08-09	10.1038/s41586-023-06395-9
8JPC	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin 8-13	PubChem 118610427; GDP; Mg	Gq; GRK2	3.07	2023-08-09	10.1038/s41586-023-06395-9
8JPF	A	Peptide	Neurotensin	NTS₁	Homo sapiens	Neurotensin	PubChem 118610427	-	3.02	2023-08-09	10.1038/s41586-023-06395-9
8IU2	A	Sensory	Opsins	Opsin1LW	Homo sapiens	Retinal	-	Gi1/&β;1/&γ;2	3.35	2024-03-27	To be published
8F76	A	Olfactory receptors	Olfactory	OR51E2	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.1	2023-03-22	10.1038/s41586-023-05798-y
8HTI	A	Olfactory receptors	Olfactory	OR52C	Homo sapiens	Ocatnoic Acid	-	Gs/&β;1/&γ;2	2.97	2023-12-20	10.1038/s41467-023-43983-9
8J46	A	Olfactory receptors	Olfactory	OR52C	Homo sapiens	-	-	-	3.66	2023-12-20	10.1038/s41467-023-43983-9
8W77	A	Olfactory receptors	Olfactory	OR52C	Homo sapiens	-	-	-	3.61	2023-12-20	10.1038/s41467-023-43983-9
6TPK	A	Peptide	Vasopressin and oxytocin	OT	Homo sapiens	Retosiban	-	-	3.2	2020-08-05	10.1126/sciadv.abb5419
7QVM	A	Peptide	Vasopressin and oxytocin	OT	Homo sapiens	Oxytocin	-	chim(NtGi1-Go-CtGq)/&β;1/&γ;2	3.25	2022-08-10	10.1038/s41467-022-31325-0
7RYC	A	Peptide	Vasopressin and oxytocin	OT	Homo sapiens	Oxytocin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	2.9	2022-03-09	10.1038/s41594-022-00728-4
4ZJ8	A	Peptide	Orexin	OX₁	Homo sapiens	Suvorexant	-	-	2.75	2016-03-09	10.1038/nsmb.3183
4ZJC	A	Peptide	Orexin	OX₁	Homo sapiens	SB-674042	-	-	2.83	2016-03-09	10.1038/nsmb.3183
6TO7	A	Peptide	Orexin	OX₁	Homo sapiens	Suvorexant	Na	-	2.26	2020-01-01	10.1021/acs.jmedchem.9b01787
6TOD	A	Peptide	Orexin	OX₁	Homo sapiens	EMPA	Na	-	2.11	2020-01-01	10.1021/acs.jmedchem.9b01787
6TOS	A	Peptide	Orexin	OX₁	Homo sapiens	GSK1059865	Na	-	2.13	2020-01-15	10.1021/acs.jmedchem.9b01787
6TOT	A	Peptide	Orexin	OX₁	Homo sapiens	Lemborexant	-	-	2.22	2020-01-15	10.1021/acs.jmedchem.9b01787
6TP3	A	Peptide	Orexin	OX₁	Homo sapiens	Nemorexant	-	-	3.04	2020-01-01	10.1021/acs.jmedchem.9b01787
6TP4	A	Peptide	Orexin	OX₁	Homo sapiens	ACT-462206	-	-	3.01	2020-01-01	10.1021/acs.jmedchem.9b01787
6TP6	A	Peptide	Orexin	OX₁	Homo sapiens	Filorexant	-	-	2.34	2020-01-01	10.1021/acs.jmedchem.9b01787
6TQ4	A	Peptide	Orexin	OX₁	Homo sapiens	PubChem 16046844	Na	-	2.3	2020-01-01	10.1021/acs.jmedchem.9b01787
6TQ6	A	Peptide	Orexin	OX₁	Homo sapiens	PubChem 145714283	-	-	2.55	2020-01-01	10.1021/acs.jmedchem.9b01787
6TQ7	A	Peptide	Orexin	OX₁	Homo sapiens	SB-334867	-	-	2.66	2020-01-01	10.1021/acs.jmedchem.9b01787
6TQ9	A	Peptide	Orexin	OX₁	Homo sapiens	SB-408124	-	-	2.65	2020-01-01	10.1021/acs.jmedchem.9b01787
6V9S	A	Peptide	Orexin	OX₁	Homo sapiens	GTPL11403	-	-	3.5	2020-07-15	10.1073/pnas.2002704117
4S0V	A	Peptide	Orexin	OX₂	Homo sapiens	Suvorexant	-	-	2.5	2015-01-14	10.1038/nature14035
5WQC	A	Peptide	Orexin	OX₂	Homo sapiens	EMPA	-	-	1.96	2017-11-29	10.1016/j.str.2017.11.005
5WS3	A	Peptide	Orexin	OX₂	Homo sapiens	EMPA	-	-	2.3	2017-12-13	10.1016/j.str.2017.11.005
6TPG	A	Peptide	Orexin	OX₂	Homo sapiens	EMPA	-	-	2.74	2020-01-01	10.1021/acs.jmedchem.9b01787
6TPJ	A	Peptide	Orexin	OX₂	Homo sapiens	Suvorexant	-	-	2.74	2020-01-01	10.1021/acs.jmedchem.9b01787
6TPN	A	Peptide	Orexin	OX₂	Homo sapiens	HTL6641	-	-	2.61	2020-01-01	10.1021/acs.jmedchem.9b01787
7L1U	A	Peptide	Orexin	OX₂	Homo sapiens	Orexin	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.2	2021-02-10	10.1038/s41467-021-21087-6
7L1V	A	Peptide	Orexin	OX₂	Homo sapiens	PubChem 155491009	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3	2021-02-10	10.1038/s41467-021-21087-6
7SQO	A	Peptide	Orexin	OX₂	Homo sapiens	TAK-925	-	Gi1/&β;1/&γ;2	3.17	2022-05-25	10.1038/s41467-022-30601-3
7SR8	A	Peptide	Orexin	OX₂	Homo sapiens	TAK-925	-	chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2	3.3	2022-06-08	10.1038/s41467-022-30601-3
7XRR	A	Peptide	Orexin	OX₂	Homo sapiens	Lemborexant	-	-	2.89	2022-11-23	10.1016/j.str.2022.11.001
4XNV	A	Nucleotide	P2Y	P2Y₁	Homo sapiens	-	BPTU	-	2.2	2015-04-01	10.1038/nature14287
4XNW	A	Nucleotide	P2Y	P2Y₁	Homo sapiens	MRS2500	-	-	2.7	2015-04-01	10.1038/nature14287
7XXH	A	Nucleotide	P2Y	P2Y₁	Homo sapiens	2MeSADP	-	chim(NtGi1-G11)/&β;1/&γ;2	2.9	2023-06-07	10.1093/procel/pwac025
4NTJ	A	Nucleotide	P2Y	P2Y₁₂	Homo sapiens	AZD1283	-	-	2.62	2014-03-26	10.1038/nature13083
4PXZ	A	Nucleotide	P2Y	P2Y₁₂	Homo sapiens	2MeSADP	-	-	2.5	2014-04-30	10.1038/nature13288
4PY0	A	Nucleotide	P2Y	P2Y₁₂	Homo sapiens	2MeSATP	-	-	3.1	2014-04-30	10.1038/nature13288
7PP1	A	Nucleotide	P2Y	P2Y₁₂	Homo sapiens	Selatogrel	-	-	2.78	2022-11-02	10.1016/j.bcp.2022.115291
7XXI	A	Nucleotide	P2Y	P2Y₁₂	Homo sapiens	2MeSADP	-	Gi2/&β;1/&γ;2	3	2023-06-07	10.1093/procel/pwac025
6LPB	B1	Peptide	VIP and PACAP	PAC₁	Homo sapiens	PACAP	-	Gs/&β;1/&γ;1	3.9	2020-03-11	10.1038/s41594-020-0386-8
6M1H	B1	Peptide	VIP and PACAP	PAC₁	Homo sapiens	Maxadilan	-	Gs/&β;1/&γ;2	3.6	2020-03-11	10.1038/s41422-020-0280-2
6M1I	B1	Peptide	VIP and PACAP	PAC₁	Homo sapiens	PACAP	-	Gs/&β;1/&γ;2	3.5	2020-03-11	10.1038/s41422-020-0280-2
6P9Y	B1	Peptide	VIP and PACAP	PAC₁	Homo sapiens	PACAP	-	Gs/&β;1/&γ;2	3.01	2020-02-05	10.1016/j.molcel.2020.01.012
8E3X	B1	Peptide	VIP and PACAP	PAC₁	Homo sapiens	PACAP27	-	Gs/&β;1/&γ;2	2.3	2022-11-23	10.1038/s41467-022-34629-3
5ZKP	A	Lipid	Platelet-activating factor	PAF	Homo sapiens	Foropafant (SR27417)	-	-	2.81	2018-06-20	10.1038/s41594-018-0068-y
5ZKQ	A	Lipid	Platelet-activating factor	PAF	Homo sapiens	ABT-491	-	-	2.9	2018-06-20	10.1038/s41594-018-0068-y
3VW7	A	Peptide	Proteinase-activated	PAR1	Homo sapiens	-	Vorapaxar; Na	-	2.2	2012-12-12	10.1038/nature11701
5NDD	A	Peptide	Proteinase-activated	PAR2	Homo sapiens	-	AZ8838; Na	-	2.8	2017-05-03	10.1038/nature22309
5NDZ	A	Peptide	Proteinase-activated	PAR2	Homo sapiens	-	AZ3451; Na	-	3.6	2017-05-03	10.1038/nature22309
5NJ6	A	Peptide	Proteinase-activated	PAR2	Homo sapiens	-	-	-	4	2017-05-03	10.1038/nature22309
6FJ3	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	-	2.5	2018-11-21	10.1038/s41594-018-0151-4
6NBF	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH analog	-	Gs/&β;1/&γ;2	3	2019-04-17	10.1126/science.aav7942
6NBH	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH analog	-	Gs/&β;1/&γ;2	3.5	2019-04-17	10.1126/science.aav7942
6NBI	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH analog	-	Gs/&β;1/&γ;2	4	2019-04-17	10.1126/science.aav7942
7VVJ	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/&β;1/&γ;2	3.2	2022-08-03	10.1016/j.molcel.2022.07.003
7VVK	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	3.3	2022-08-03	10.1016/j.molcel.2022.07.003
7VVL	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	2.8	2022-08-03	10.1016/j.molcel.2022.07.003
7VVM	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	3.2	2022-08-03	10.1016/j.molcel.2022.07.003
7VVN	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	3.8	2022-08-03	10.1016/j.molcel.2022.07.003
7VVO	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	4.1	2022-08-03	10.1016/j.molcel.2022.07.003
7Y35	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/&β;1/&γ;2	2.9	2023-07-05	To be published
7Y36	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Teriparatide	-	Gs/&β;1/&γ;2	2.8	2023-07-05	To be published
8FLQ	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	Gs/&β;1/&γ;2	2.55	2023-04-26	10.1016/j.str.2023.04.002
8FLR	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/&β;1/&γ;2	2.94	2023-04-26	10.1016/j.str.2023.04.002
8FLS	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/&β;1/&γ;2	3.09	2023-04-26	10.1016/j.str.2023.04.002
8FLT	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	M-PTH(1-14)	-	Gs/&β;1/&γ;2	3.03	2023-04-26	10.1016/j.str.2023.04.002
8FLU	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	Long-acting PTH	-	Gs/&β;1/&γ;2	2.76	2023-04-26	10.1016/j.str.2023.04.002
8GW8	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	-	KHF	Gs/&β;1/&γ;2	2.9	2023-06-14	10.1038/s41586-023-06169-3
8HA0	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.62	2022-12-21	10.1038/s41401-022-01032-z
8HAF	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.25	2022-12-21	10.1038/s41401-022-01032-z
8HAO	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.76	2022-12-21	10.1038/s41401-022-01032-z
8JR9	B1	Peptide	Parathyroid hormone	PTH1	Homo sapiens	-	PCO371	chim(NtGi1-Gs)/&β;1/&γ;2	2.57	2023-08-02	10.1038/s41586-023-06467-w
7F16	B1	Peptide	Parathyroid hormone	PTH2	Homo sapiens	TIP39	-	Gs/&β;1/&γ;2	2.8	2021-08-18	10.1073/pnas.2101279118
1F88	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2000-08-04	10.1126/science.289.5480.739
1GZM	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2003-11-20	10.1016/j.jmb.2004.08.090
1HZX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.8	2001-07-04	10.1021/bi0155091
1L9H	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2002-05-15	10.1073/pnas.082666399
1U19	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.2	2004-10-12	10.1016/j.jmb.2004.07.044
2G87	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	2.6	2006-09-02	10.1002/anie.200600595
2HPY	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	2.8	2006-08-22	10.1073/pnas.0601765103
2I35	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.8	2006-10-17	10.1073/pnas.0608022103
2I36	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.1	2006-10-17	10.1073/pnas.0608022103
2I37	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.15	2006-10-17	10.1073/pnas.0608022103
2J4Y	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2007-09-25	10.1016/j.jmb.2007.03.007
2PED	A	Sensory	Opsins	Rhodopsin	Bos taurus	9-cis-Retinal	-	-	2.95	2007-10-30	10.1529/biophysj.107.108225
2X72	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	3	2011-03-16	10.1038/nature09795
2Z73	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	2.5	2008-05-13	10.1038/nature06925
2ZIY	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	11-cis-Retinal	-	-	3.7	2008-05-06	10.1074/jbc.C800040200
3AYM	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-retinal	-	-	2.8	2011-08-17	10.1016/j.jmb.2011.08.044
3AYN	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	9-cis-Retinal	-	-	2.7	2011-08-17	10.1016/j.jmb.2011.08.044
3C9L	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.65	2008-08-05	10.1107/S0907444908017162
3C9M	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.4	2008-08-05	10.1107/S0907444908017162
3CAP	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	2.9	2008-06-24	10.1038/nature07063
3DQB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	3.2	2008-09-23	10.1038/nature07330
3OAX	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	2.6	2011-01-19	10.1016/j.bpj.2010.08.003
3PQR	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	2.85	2011-03-09	10.1038/nature09789
3PXO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	3	2011-03-09	10.1038/nature09789
4A4M	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	3.3	2012-01-25	10.1073/pnas.1114089108
4BEY	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	2.9	2013-05-08	10.1038/embor.2013.44
4BEZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.3	2013-04-24	10.1038/embor.2013.44
4J4Q	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Gt(CT)	2.65	2013-10-30	10.1002/anie.201302374
4PXF	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Arrestin1_Finger_loop	2.75	2014-09-17	10.1038/ncomms5801
4WW3	A	Sensory	Opsins	Rhodopsin	Todarodes pacificus	All-trans-retinal	-	-	2.8	2015-06-17	10.1371/journal.pone.0126970
4X1H	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl Beta-D-Glucopyranoside	-	Gt(CT)	2.29	2015-11-04	10.1016/j.str.2015.09.015
4ZWJ	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.3	2015-07-29	10.1038/nature14656
5DGY	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	7.7	2016-03-23	10.1038/sdata.2016.21
5DYS	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	2.3	2016-08-10	10.15252/embr.201642671
5EN0	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt(CT)	2.81	2016-08-10	10.15252/embr.201642671
5TE3	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	-	2.7	2017-03-15	10.1073/pnas.1617446114
5TE5	A	Sensory	Opsins	Rhodopsin	Bos taurus	20-Methanoretinal	-	-	4.01	2017-03-15	10.1073/pnas.1617446114
5W0P	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Arrestin1	3.01	2017-08-09	10.1016/j.cell.2017.07.002
5WKT	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Gt(CT)	3.2	2017-12-13	10.1038/nprot.2017.135
6CMO	A	Sensory	Opsins	Rhodopsin	Homo sapiens	-	-	Gi1/&β;1/&γ;2	4.5	2018-06-20	10.1038/s41586-018-0215-y
6FK6	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473033	-	2.36	2018-04-04	10.1073/pnas.1718084115
6FK7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473034	-	2.62	2018-04-04	10.1073/pnas.1718084115
6FK8	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473035	-	2.87	2018-04-04	10.1073/pnas.1718084115
6FK9	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473036	-	2.63	2018-04-04	10.1073/pnas.1718084115
6FKA	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473037	-	2.7	2018-04-04	10.1073/pnas.1718084115
6FKB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473038	-	3.03	2018-04-04	10.1073/pnas.1718084115
6FKC	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 132473039	-	2.46	2018-04-04	10.1073/pnas.1718084115
6FKD	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	PubChem 137349183	-	2.49	2018-04-04	10.1073/pnas.1718084115
6FUF	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Go/&β;1/&γ;2	3.12	2018-10-03	10.1126/sciadv.aat7052
6I9K	A	Sensory	Opsins	Rhodopsin	Hasarius adansoni	9-cis-Retinal	-	-	2.15	2019-07-03	10.1073/pnas.1902192116
6NWE	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl Beta-D-Glucopyranoside	-	Gt(CT)	2.71	2020-02-12	To be published
6OFJ	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.5	2019-08-21	10.1074/jbc.RA119.010089
6OY9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt/&β;1/&γ;1	3.9	2019-07-24	10.1016/j.molcel.2019.06.007
6OYA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gt/&β;1/&γ;1	3.3	2019-07-24	10.1016/j.molcel.2019.06.007
6PEL	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol	Gt(CT)	3.19	2020-06-24	To be published
6PGS	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol	Gt(CT)	2.9	2020-07-01	To be published
6PH7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol	Gt(CT)	2.9	2020-07-01	To be published
6QNO	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	Gi1/&β;1/&γ;1	4.38	2019-07-10	10.7554/eLife.46041
7MT8	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	5.8	2021-07-07	10.1038/s41586-021-03721-x
7MT9	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	7	2021-07-07	10.1038/s41586-021-03721-x
7MTA	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	4.1	2021-07-07	10.1038/s41586-021-03721-x
7MTB	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	GRK1	4	2021-07-07	10.1038/s41586-021-03721-x
7ZBC	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
7ZBE	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
8A6C	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
8A6D	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
8A6E	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-retinal	-	-	1.8	2023-03-29	10.1038/s41586-023-05863-6
8FCZ	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.7	2023-08-30	10.1038/s41467-023-40911-9
8FD0	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.71	2023-08-30	10.1038/s41467-023-40911-9
8FD1	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	10.1038/s41467-023-40911-9
7TMW	A	Peptide	Relaxin	RXFP1	Homo sapiens	-	-	Gs/&β;1/&γ;2	3.2	2023-02-15	10.1101/2022.01.22.477343
7YJ4	A	Peptide	Relaxin	RXFP4	Homo sapiens	INSL5	-	Gi2/&β;1/&γ;2	3.19	2023-03-01	10.1038/s41467-023-36182-z
7YK6	A	Peptide	Relaxin	RXFP4	Homo sapiens	PubChem 138319674	-	Gi2/&β;1/&γ;2	3.03	2023-03-01	10.1038/s41467-023-36182-z
7YK7	A	Peptide	Relaxin	RXFP4	Homo sapiens	DC591053	-	Gi2/&β;1/&γ;2	2.75	2023-03-01	10.1038/s41467-023-36182-z
3V2W	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	PubChem 51892645	-	-	3.35	2012-02-15	10.1126/science.1215904
3V2Y	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	PubChem 51892645	-	-	2.8	2012-02-15	10.1126/science.1215904
7EO2	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	FTY720-P	-	Gi1/&β;1/&γ;2	2.89	2022-01-05	10.1038/s41589-021-00930-3
7EO4	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	BAF312	-	Gi1/&β;1/&γ;2	2.86	2022-01-05	10.1038/s41589-021-00930-3
7EVY	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	Siponimod	-	Gi1/&β;1/&γ;2	2.98	2021-09-29	10.1038/s41422-021-00566-x
7EVZ	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	Cenerimod	-	Gi1/&β;1/&γ;2	3.07	2021-09-29	10.1038/s41422-021-00566-x
7EW0	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	Ozanimod	-	Gi1/&β;1/&γ;2	3.42	2021-09-29	10.1038/s41422-021-00566-x
7EW7	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	PubChem 4077460	-	Gi1/&β;1/&γ;2	3.27	2021-09-29	10.1038/s41422-021-00566-x
7TD3	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	S1P	-	Gi1/&β;1/&γ;2	3	2022-02-09	10.1038/s41467-022-28417-2
7TD4	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	Siponimod	-	Gi1/&β;1/&γ;2	2.6	2022-02-09	10.1038/s41467-022-28417-2
7VIE	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	S1P	-	Gi1/&β;1/&γ;2	2.86	2022-09-28	10.1073/pnas.2117716119
7VIF	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	(S)-FTY720-P	-	Gi1/&β;1/&γ;2	2.83	2022-09-28	10.1073/pnas.2117716119
7VIG	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	CBP-307	-	Gi1/&β;1/&γ;2	2.89	2022-09-28	10.1073/pnas.2117716119
7VIH	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	CBP-307	-	Gi1/&β;1/&γ;2	2.98	2022-09-28	10.1073/pnas.2117716119
7WF7	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	S1P	-	Gi1/&β;1/&γ;2	3.4	2022-01-05	10.1038/s41589-021-00930-3
8G94	A	Lipid	Lysophospholipid (S1P)	S1P₁	Homo sapiens	-	CD69	Gi1/&β;1/&γ;2	3.15	2023-04-19	10.7554/eLife.88204
7T6B	A	Lipid	Lysophospholipid (S1P)	S1P₂	Homo sapiens	S1P	-	chim(NtGi1L-G13)/&β;1/&γ;2	3.19	2022-04-06	10.1126/sciadv.abn0067
7C4S	A	Lipid	Lysophospholipid (S1P)	S1P₃	Homo sapiens	S1P	-	-	3.2	2021-06-09	10.1126/sciadv.abf5325
7EW2	A	Lipid	Lysophospholipid (S1P)	S1P₃	Homo sapiens	Fingolimod	-	Gi1/&β;1/&γ;2	3.1	2021-09-29	10.1038/s41422-021-00567-w
7EW3	A	Lipid	Lysophospholipid (S1P)	S1P₃	Homo sapiens	S1P	-	Gi1/&β;1/&γ;2	3.1	2021-09-29	10.1038/s41422-021-00567-w
7EW4	A	Lipid	Lysophospholipid (S1P)	S1P₃	Homo sapiens	CYM5541	-	Gi1/&β;1/&γ;2	3.2	2021-09-29	10.1038/s41422-021-00567-w
7EW1	A	Lipid	Lysophospholipid (S1P)	S1P₅	Homo sapiens	Siponimod	-	Gi1/&β;1/&γ;2	3.4	2021-09-29	10.1038/s41422-021-00566-x
7YXA	A	Lipid	Lysophospholipid (S1P)	S1P₅	Homo sapiens	ONO-5430608	-	-	2.2	2022-08-10	10.1038/s41467-022-32447-1
6WI9	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/&β;1/&γ;2	4.3	2020-08-12	10.1038/s41467-020-17791-4
6WZG	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/&β;1/&γ;2	2.3	2020-08-12	10.1038/s41467-020-17791-4
7D3S	B1	Peptide	Glucagon	Secretin	Homo sapiens	Secretin	-	Gs/&β;1/&γ;2	2.9	2020-11-04	10.1016/j.bbrc.2020.08.042
4JKV	F	Protein	Frizzled	SMO	Homo sapiens	Taladegib (LY2940680)	-	-	2.45	2013-04-24	10.1038/nature12167
4N4W	F	Protein	Frizzled	SMO	Homo sapiens	-	SANT-1	-	2.8	2014-01-22	10.1038/ncomms5355
4O9R	F	Protein	Frizzled	SMO	Homo sapiens	Cyclopamine	-	-	3.2	2014-03-05	10.1038/ncomms4309
4QIM	F	Protein	Frizzled	SMO	Homo sapiens	PubChem 24905375	-	-	2.61	2014-07-23	10.1038/ncomms5355
4QIN	F	Protein	Frizzled	SMO	Homo sapiens	SAG1.5	-	-	2.6	2014-07-23	10.1038/ncomms5355
5L7D	F	Protein	Frizzled	SMO	Homo sapiens	-	Cholesterol	-	3.2	2016-07-20	10.1038/nature18934
5L7I	F	Protein	Frizzled	SMO	Homo sapiens	Vismodegib	-	-	3.3	2016-07-20	10.1038/nature18934
5V56	F	Protein	Frizzled	SMO	Homo sapiens	TC114	-	-	2.9	2017-05-24	10.1038/ncomms15383
5V57	F	Protein	Frizzled	SMO	Homo sapiens	TC114	-	-	3	2017-05-24	10.1038/ncomms15383
6D32	F	Protein	Frizzled	SMO	Xenopus laevis	Cyclopamine	Cyclopamine	-	3.75	2018-05-23	10.1016/j.cell.2018.04.029
6D35	F	Protein	Frizzled	SMO	Xenopus laevis	-	Cholesterol	-	3.9	2018-05-23	10.1016/j.cell.2018.04.029
6O3C	F	Protein	Frizzled	SMO	Mus musculus	SAG21k	Cholesterol	-	2.8	2019-07-03	10.1038/s41586-019-1355-4
6OT0	F	Protein	Frizzled	SMO	Homo sapiens	-	25(S)-Epoxycholesterol	Gi1/&β;1/&γ;2	3.84	2019-06-12	10.1038/s41586-019-1286-0
6XBJ	F	Protein	Frizzled	SMO	Homo sapiens	-	Cholesterol	Gi1/&β;1/&γ;2	3.88	2020-09-30	10.1038/s41589-020-0646-2
6XBK	F	Protein	Frizzled	SMO	Homo sapiens	-	Cholesterol	Gi1/&β;1/&γ;2	3.24	2020-09-30	10.1038/s41589-020-0646-2
6XBL	F	Protein	Frizzled	SMO	Homo sapiens	SAG	Cholesterol	Gi1/&β;1/&γ;2	3.96	2020-09-30	10.1038/s41589-020-0646-2
6XBM	F	Protein	Frizzled	SMO	Homo sapiens	-	25(S)-Epoxycholesterol	Gi1/&β;1/&γ;2	3.14	2020-09-30	10.1038/s41589-020-0646-2
7ZI0	F	Protein	Frizzled	SMO	Homo sapiens	SAG	Cholesterol	-	3	2022-06-15	10.1126/sciadv.abm5563
8CXO	F	Protein	Frizzled	SMO	Mus musculus	-	-	-	3.7	2022-08-03	10.1038/s41467-022-32125-2
7UL5	A	Peptide	Somatostatin	SST2	Homo sapiens	-	-	-	3.1	2022-06-29	10.1038/s41594-022-00859-8
7WIC	A	Peptide	Somatostatin	SST2	Homo sapiens	Somatostatin-14	-	Gi1/&β;1/&γ;2	2.8	2022-06-01	10.1038/s41422-022-00669-z
7WIG	A	Peptide	Somatostatin	SST2	Homo sapiens	L-054,264	-	Gi1/&β;1/&γ;2	2.7	2022-06-01	10.1038/s41422-022-00669-z
7WJ5	A	Peptide	Somatostatin	SST2	Homo sapiens	Somatostatin-14	-	Gi1/&β;1/&γ;2	3.72	2022-07-13	10.7554/eLife.76823
7XAT	A	Peptide	Somatostatin	SST2	Homo sapiens	Somatostatin-14	-	Gi1/&β;1/&γ;2	2.85	2022-08-31	10.1038/s41421-022-00405-2
7XAU	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-	Gi1/&β;1/&γ;2	2.97	2022-08-31	10.1038/s41421-022-00405-2
7XAV	A	Peptide	Somatostatin	SST2	Homo sapiens	Lanreotide	-	Gi1/&β;1/&γ;2	2.87	2022-08-31	10.1038/s41421-022-00405-2
7XMR	A	Peptide	Somatostatin	SST2	Homo sapiens	Somatostatin-14	-	Gi1/&β;1/&γ;2	3.1	2022-08-03	10.1038/s41422-022-00679-x
7XN9	A	Peptide	Somatostatin	SST2	Homo sapiens	L-054,522	-	-	2.6	2022-08-03	10.1038/s41422-022-00679-x
7XNA	A	Peptide	Somatostatin	SST2	Homo sapiens	CYN154806	-	-	2.65	2022-08-03	10.1038/s41422-022-00679-x
7Y24	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-	Go/&β;1/&γ;2	3.25	2022-10-19	10.1038/s41589-022-01130-3
7Y26	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.3	2022-10-19	10.1038/s41589-022-01130-3
7Y27	A	Peptide	Somatostatin	SST2	Homo sapiens	Somatostatin-14	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.48	2022-10-19	10.1038/s41589-022-01130-3
7YAC	A	Peptide	Somatostatin	SST2	Homo sapiens	Paltusotine	-	Gi1/&β;1/&γ;2	3.24	2023-04-19	10.1038/s41467-023-36673-z
7YAE	A	Peptide	Somatostatin	SST2	Homo sapiens	Octreotide	-	Gi1/&β;1/&γ;2	3.37	2023-04-19	10.1038/s41467-023-36673-z
7XMS	A	Peptide	Somatostatin	SST4	Homo sapiens	Somatostatin-14	-	Gi1/&β;1/&γ;2	2.9	2022-08-03	10.1038/s41422-022-00679-x
7XMT	A	Peptide	Somatostatin	SST4	Homo sapiens	J-2156	-	Gi1/&β;1/&γ;2	2.8	2022-08-03	10.1038/s41422-022-00679-x
7AD3	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	Alpha-factor mating pheromone	-	Gi1/STE4/&γ;2	3.3	2020-12-09	10.1038/s41586-020-2994-1
7QA8	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	Peptide	-	-	2.7	2022-03-16	10.1038/s41586-022-04498-3
7QB9	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	-	-	-	3.1	2022-03-16	10.1038/s41586-022-04498-3
7QBC	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	Alpha-factor mating pheromone	-	-	3.53	2022-03-16	10.1038/s41586-022-04498-3
7QBI	D1	Ste2-like	STE2	STE2	Saccharomyces cerevisiae	Alpha-factor mating pheromone	-	-	3.46	2022-03-16	10.1038/s41586-022-04498-3
6IBB	A	Alicarboxylic acid	Succinate	Succinate	Rattus norvegicus	-	-	-	2.12	2019-08-14	10.1038/s41586-019-1663-8
6RNK	A	Alicarboxylic acid	Succinate	Succinate	Rattus norvegicus	NF-56-EJ40	-	-	1.94	2019-08-14	10.1038/s41586-019-1663-8
6Z10	A	Alicarboxylic acid	Succinate	Succinate	Rattus norvegicus	PubChem 154585554	-	-	2.27	2020-09-16	10.1021/acs.jmedchem.0c01020
7XP4	T	Sensory	Taste2	T2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/&β;1/&γ;2	3.01	2022-10-12	10.1126/science.abo1633
7XP5	T	Sensory	Taste2	T2R46	Homo sapiens	-	-	chim(Gs-CtGt3)/&β;1/&γ;2	3.08	2022-10-12	10.1126/science.abo1633
7XP6	T	Sensory	Taste2	T2R46	Homo sapiens	Strychnine	-	chim(Gs-CtGt3)/&β;1/&γ;2	3.01	2022-10-12	10.1126/science.abo1633
8JLJ	A	Amine	Trace amine receptors	TA1	Mus musclus	T1AM	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2023-11-15	10.1038/s41586-023-06804-z
8JLK	A	Amine	Trace amine receptors	TA1	Mus musclus	Ulotaront	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.22	2023-11-15	10.1038/s41586-023-06804-z
8JLN	A	Amine	Trace amine receptors	TA1	Homo sapiens	T1AM	-	Gs/&β;1/&γ;2	3.24	2023-11-15	10.1038/s41586-023-06804-z
8JLO	A	Amine	Trace amine receptors	TA1	Homo sapiens	Ulotaront	-	Gs/&β;1/&γ;2	3.52	2023-11-15	10.1038/s41586-023-06804-z
8JLP	A	Amine	Trace amine receptors	TA1	Homo sapiens	Ralmitaront	-	Gs/&β;1/&γ;2	3.23	2023-11-15	10.1038/s41586-023-06804-z
8JLQ	A	Amine	Trace amine receptors	TA1	Homo sapiens	Fenoldopam	-	Gs/&β;1/&γ;2	2.84	2023-11-15	10.1038/s41586-023-06804-z
8JLR	A	Amine	Trace amine receptors	TA1	Homo sapiens	A77636	-	chim(NtGi1-Gs)/&β;1/&γ;2	3	2023-11-15	10.1038/s41586-023-06804-z
8JSO	A	Amine	Trace amine receptors	TA1	Homo sapiens	AMPH	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.4	2023-11-15	10.1038/s41586-023-06804-z
8UHB	A	Amine	Trace amine receptors	TA1	Homo sapiens	RO5256390	-	Gs/&β;1/&γ;2	3.35	2024-01-10	10.1038/s41467-023-44601-4
8W87	A	Amine	Trace amine receptors	TA1	Homo sapiens	METH	-	chim(NtGi1L-Gs)/&β;1/&γ;2	2.8	2023-11-22	10.1038/s41586-023-06775-1
8W88	A	Amine	Trace amine receptors	TA1	Homo sapiens	SEP-363856	-	Gs/&β;1/&γ;2	2.6	2023-11-22	10.1038/s41586-023-06775-1
8W89	A	Amine	Trace amine receptors	TA1	Homo sapiens	PEA	-	chim(NtGi1L-Gs)/&β;1/&γ;2	3	2023-11-22	10.1038/s41586-023-06775-1
8W8A	A	Amine	Trace amine receptors	TA1	Homo sapiens	RO5256390	-	chim(NtGi1L-Gs)/&β;1/&γ;2	2.8	2023-11-22	10.1038/s41586-023-06775-1
8WC3	A	Amine	Trace amine receptors	TA1	Mus musculus	SEP-363856	-	chim(NtGi1-Gs)/&β;1/&γ;2	3	2023-12-27	10.1016/j.cell.2023.10.014
8WC4	A	Amine	Trace amine receptors	TA1	Mus musculus	ZH8651	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2023-12-27	10.1016/j.cell.2023.10.014
8WC5	A	Amine	Trace amine receptors	TA1	Mus musculus	Tetramethylammonium ion	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.3	2023-12-27	10.1016/j.cell.2023.10.014
8WC6	A	Amine	Trace amine receptors	TA1	Mus musculus	2-Phenylethylamine	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.2	2023-12-27	10.1016/j.cell.2023.10.014
8WC7	A	Amine	Trace amine receptors	TA1	Mus musculus	ZH8667	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.1	2023-12-27	10.1016/j.cell.2023.10.014
8WC8	A	Amine	Trace amine receptors	TA1	Mus musculus	ZH8651	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.9	2023-12-27	10.1016/j.cell.2023.10.014
8WC9	A	Amine	Trace amine receptors	TA1	Mus musculus	ZH8651	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.2	2023-12-27	10.1016/j.cell.2023.10.014
8WCA	A	Amine	Trace amine receptors	TA1	Homo sapiens	2-Phenylethylamine	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.48	2023-12-27	10.1016/j.cell.2023.10.014
8WCB	A	Amine	Trace amine receptors	TA1	Mus musculus	Cyclohexylammonium ion	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.1	2023-12-27	10.1016/j.cell.2023.10.014
8WCC	A	Amine	Trace amine receptors	TA1	Mus musculus	Cyclohexylammonium ion	-	-	3.04	2023-12-27	10.1016/j.cell.2023.10.014
8ITF	A	Orphan	A orphans	TAAR9	Mus musculus	DMCHA	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.46	2023-05-31	10.1038/s41586-023-06106-4
8IW1	A	Orphan	A orphans	TAAR9	Mus musculus	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.4	2023-05-31	10.1038/s41586-023-06106-4
8IW4	A	Orphan	A orphans	TAAR9	Mus musculus	Spermidine	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.49	2023-05-31	10.1038/s41586-023-06106-4
8IW7	A	Orphan	A orphans	TAAR9	Mus musculus	2-Phenylethylamine	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.97	2023-05-31	10.1038/s41586-023-06106-4
8IW9	A	Orphan	A orphans	TAAR9	Mus musculus	-	-	chim(NtGi1-Gs)/&β;1/&γ;2	3.08	2023-05-31	10.1038/s41586-023-06106-4
8IWE	A	Orphan	A orphans	TAAR9	Mus musculus	Spermidine	-	-	3.4	2023-05-31	10.1038/s41586-023-06106-4
8IWM	A	Orphan	A orphans	TAAR9	Mus musculus	2-Phenylethylamine	-	-	3.17	2023-05-31	10.1038/s41586-023-06106-4
6IIU	A	Lipid	Prostanoid	TP	Homo sapiens	Ramatroban	-	-	2.5	2018-12-19	10.1038/s41589-018-0170-9
6IIV	A	Lipid	Prostanoid	TP	Homo sapiens	Daltroban	-	-	3	2018-12-19	10.1038/s41589-018-0170-9
8XJO	A	Lipid	Prostanoid	TP	Homo sapiens	U46619	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.11	2024-02-28	To be published
7WKD	A	Peptide	Thyrotropin-releasing hormone	TRH	Homo sapiens	TRH	-	chim(NtGi1-Gs-CtGq)/&β;1/&γ;2	3.01	2022-06-15	10.1038/s41422-022-00641-x
7X1T	A	Peptide	Thyrotropin-releasing hormone	TRH	Homo sapiens	Taltirelin	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.26	2022-08-31	10.1038/s41422-022-00646-6
7X1U	A	Peptide	Thyrotropin-releasing hormone	TRH	Homo sapiens	TRH	-	chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2	3.19	2022-08-31	10.1038/s41422-022-00646-6
7XW9	A	Peptide	Thyrotropin-releasing hormone	TRH	Homo sapiens	TRH	-	chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2	2.7	2022-12-28	10.1038/s41421-022-00477-0
7T9I	A	Protein	Glycoprotein hormone	TSH	Homo sapiens	TSH	-	Gs/&β;1/&γ;2	2.9	2022-08-03	10.1038/s41586-022-05159-1
7T9M	A	Protein	Glycoprotein hormone	TSH	Homo sapiens	-	CS-17 Antibody	-	3.1	2022-08-10	10.1038/s41586-022-05159-1
7T9N	A	Protein	Glycoprotein hormone	TSH	Homo sapiens	M22 Fab	PubChem 644078	Gs/&β;1/&γ;2	2.9	2022-08-03	10.1038/s41586-022-05159-1
7UTZ	A	Protein	Glycoprotein hormone	TSH	Homo sapiens	TR1402	PubChem 644078	Gs/&β;1/&γ;2	2.4	2022-08-03	10.1038/s41586-022-05159-1
7XW5	A	Protein	Glycoprotein hormone	TSH	Homo sapiens	TSH	ML109	Gs/&β;1/&γ;2	2.96	2022-08-24	10.1038/s41586-022-05173-3
7XW6	A	Protein	Glycoprotein hormone	TSH	Homo sapiens	M22 Fab	ML109	Gs/&β;1/&γ;2	2.78	2022-08-17	10.1038/s41586-022-05173-3
7XW7	A	Protein	Glycoprotein hormone	TSH	Homo sapiens	K1-70	-	-	5.5	2022-08-17	10.1038/s41586-022-05173-3
7RKX	A	Other	Unclassified	US27	Human betaherpesvirus 5	-	-	Gi1/&β;1/&γ;2	3.1	2022-01-26	10.1126/sciadv.abl5442
4XT1	A	Other	Unclassified	US28	Human cytomegalovirus (strain ad169)	Fractalkine	-	-	2.89	2015-03-04	10.1126/science.aaa5026
4XT3	A	Other	Unclassified	US28	Human cytomegalovirus (strain ad169)	Fractalkine	-	-	3.8	2015-03-04	10.1126/science.aaa5026
5WB1	A	Other	Unclassified	US28	Human cytomegalovirus (strain towne)	-	-	-	3.51	2018-06-13	10.7554/eLife.35850
5WB2	A	Other	Unclassified	US28	Human cytomegalovirus (strain towne)	CX3CL1.35	-	-	3.5	2018-06-13	10.7554/eLife.35850
7RKF	A	Other	Unclassified	US28	Human betaherpesvirus 5	Fractalkine	GDP	chim(NtGi1-G11)/&β;1/&γ;2	4	2022-01-26	10.1126/sciadv.abl5442
7RKM	A	Other	Unclassified	US28	Human betaherpesvirus 5	Fractalkine	-	Gi1/&β;1/&γ;2	3.5	2022-01-26	10.1126/sciadv.abl5442
7RKN	A	Other	Unclassified	US28	Human betaherpesvirus 5	Fractalkine	-	Gi1/&β;1/&γ;2	3.6	2022-01-26	10.1126/sciadv.abl5442
7BB6	A	Peptide	Vasopressin and oxytocin	V₂	Homo sapiens	AVP	-	Gs/&β;1/&γ;2	4.2	2021-06-02	10.1126/sciadv.abg5628
7BB7	A	Peptide	Vasopressin and oxytocin	V₂	Homo sapiens	AVP	-	Gs/&β;1/&γ;2	4.4	2021-06-02	10.1126/sciadv.abg5628
7DW9	A	Peptide	Vasopressin and oxytocin	V₂	Homo sapiens	AVP	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.6	2021-07-21	10.1038/s41422-021-00480-2
7KH0	A	Peptide	Vasopressin and oxytocin	V₂	Homo sapiens	AVP	-	chim(NtGi1-Gs)/&β;1/&γ;2	2.8	2021-05-26	10.1038/s41422-021-00483-z
7R0C	A	Peptide	Vasopressin and oxytocin	V₂	Homo sapiens	AVP	-	Arrestin2	4.73	2022-09-14	10.1126/sciadv.abo7761
6VN7	B1	Peptide	VIP and PACAP	VPAC₁	Homo sapiens	PACAP	-	Gs/&β;1/&γ;2	3.2	2020-09-02	10.1038/s41467-020-17933-8
8E3Y	B1	Peptide	VIP and PACAP	VPAC₁	Homo sapiens	PACAP27	-	Gs/&β;1/&γ;2	2.3	2022-11-23	10.1038/s41467-022-34629-3
8E3Z	B1	Peptide	VIP and PACAP	VPAC₁	Homo sapiens	VIP	-	Gs/&β;1/&γ;2	2.7	2022-11-23	10.1038/s41467-022-34629-3
7VQX	B1	Peptide	VIP and PACAP	VPAC₁	Homo sapiens	PACAP27	-	Gs/&β;1/&γ;2	2.74	2022-05-18	10.1038/s41467-022-30041-z
7WBJ	B1	Peptide	VIP and PACAP	VPAC₁	Homo sapiens	PACAP27	-	Gs/&β;1/&γ;2	3.42	2022-05-18	10.1038/s41467-022-30041-z
5ZBH	A	Peptide	Neuropeptide Y	Y₁	Homo sapiens	BMS-193885	-	-	3	2018-04-25	10.1038/s41586-018-0046-x
5ZBQ	A	Peptide	Neuropeptide Y	Y₁	Homo sapiens	UR-MK-299	-	-	2.7	2018-04-25	10.1038/s41586-018-0046-x
7VGX	A	Peptide	Neuropeptide Y	Y₁	Homo sapiens	Neuropeptide Y	-	Gi1/&β;1/&γ;2	3.2	2022-02-23	10.1038/s41467-022-28510-6
7X9A	A	Peptide	Neuropeptide Y	Y₁	Homo sapiens	Neuropeptide Y	-	Gi1/&β;1/&γ;2	3.2	2022-05-18	10.1126/sciadv.abm1232
7DDZ	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	JNJ-31020028	-	-	2.8	2021-01-27	10.1038/s41467-021-21030-9
7X9B	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide Y	-	Gi1/&β;1/&γ;2	3.4	2022-05-18	10.1126/sciadv.abm1232
7YON	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Peptide YY(3-36)	-	Gi1/&β;1/&γ;2	2.95	2023-03-22	10.1016/j.str.2022.11.010
7YOO	A	Peptide	Neuropeptide Y	Y₂	Homo sapiens	Neuropeptide Y	-	Gi1/&β;1/&γ;2	3.11	2023-03-22	10.1016/j.str.2022.11.010
7X9C	A	Peptide	Neuropeptide Y	Y₄	Homo sapiens	Pancreatic Hormone	-	Gi1/&β;1/&γ;2	3	2022-05-18	10.1126/sciadv.abm1232
3CAP (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	2.9	2008-06-24	10.1038/nature07063
3ODU (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	2.5	2010-10-27	10.1126/science.1194396
3OE8 (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
3OE9 (Dimer)	A	Protein	Chemokine	CXCR4	Homo sapiens	-	IT1t	-	3.1	2010-10-27	10.1126/science.1194396
4DJH (Dimer)	A	Peptide	Opioid	κ	Homo sapiens	JDTic	-	-	2.9	2012-03-21	10.1038/nature10939
4GPO (Dimer)	A	Amine	Adrenergic	β₁	Meleagris gallopavo	-	-	-	3.5	2013-02-27	10.1038/nsmb.2504
4JKV (Dimer)	F	Protein	Frizzled	SMO	Homo sapiens	Taladegib (LY2940680)	-	-	2.45	2013-04-24	10.1038/nature12167
5O9H (Dimer)	A	Peptide	Complement peptide	C5a₁	Homo sapiens	-	NDT9513727	-	2.7	2018-01-10	10.1038/nature25025
6AK3 (Dimer)	A	Lipid	Prostanoid	EP₃	Homo sapiens	Dinoprostone IPGE2	-	-	2.9	2018-12-05	10.1038/s41589-018-0171-8
6KUW (Dimer)	A	Amine	Adrenergic	α_2c	Homo sapiens	PubChem 57213234	-	-	2.8	2019-12-04	10.1038/nature06325
6OFJ (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.5	2019-08-21	10.1074/jbc.RA119.010089
6WGT (Dimer)	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	LSD	-	-	3.4	2020-09-23	10.1016/j.cell.2020.08.024
6WH4 (Dimer)	A	Amine	5-Hydroxytryptamine	5-HT_2A	Homo sapiens	Methiothepin	-	-	3.4	2020-09-23	10.1016/j.cell.2020.08.024
6YVR (Dimer)	A	Peptide	Neurotensin	NTS₁	Rattus norvegicus	NTS8-13	-	-	2.46	2021-02-10	10.1126/sciadv.abe5504
8FCZ (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	11-cis-Retinal	-	-	3.7	2023-08-30	10.1038/s41467-023-40911-9
8FD0 (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	3.71	2023-08-30	10.1038/s41467-023-40911-9
8FD1 (Dimer)	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	10.1038/s41467-023-40911-9

psnGPCRdb

Receptors → Single PSN