psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D103	17.53	Yes	Yes	1	0	7
2	L:L:?1	R:R:I104	22.32	Yes	No	0	0	6
3	L:L:?1	R:R:S107	7.15	Yes	No	0	0	7
4	L:L:?1	R:R:L190	17.88	Yes	No	1	0	4
5	L:L:?1	R:R:S198	9.19	Yes	No	0	0	7
6	L:L:?1	R:R:S202	4.08	Yes	No	0	0	6
7	L:L:?1	R:R:F288	11.59	Yes	Yes	1	0	7
8	L:L:?1	R:R:F289	6.62	Yes	Yes	1	0	7
9	L:L:?1	R:R:N292	3.73	Yes	Yes	1	0	6
10	L:L:?1	R:R:W321	5.42	Yes	Yes	1	0	7
11	L:L:?1	W:W:?1	31.98	Yes	Yes	1	0	0
12	R:R:L30	R:R:W318	9.11	No	No	0	7	5
13	R:R:I34	R:R:M78	5.83	No	No	0	6	7
14	R:R:S325	R:R:T37	6.4	No	No	0	6	7
15	R:R:L39	R:R:L43	4.15	No	No	0	4	7
16	R:R:D70	R:R:N41	6.73	Yes	Yes	0	9	9
17	R:R:N41	R:R:P328	8.15	Yes	No	0	9	9
18	R:R:F341	R:R:V44	5.24	Yes	Yes	0	7	9
19	R:R:A47	R:R:F341	4.16	No	Yes	0	8	7
20	R:R:R55	R:R:V48	3.92	No	No	0	8	8
21	R:R:I64	R:R:V48	9.22	No	No	0	6	8
22	R:R:F51	R:R:H53	4.53	Yes	No	0	6	6
23	R:R:F51	R:R:T343	5.19	Yes	No	0	6	4
24	R:R:R52	R:R:R55	31.99	No	No	0	7	8
25	R:R:H53	R:R:L54	10.29	No	No	0	6	9
26	R:R:F337	R:R:L54	6.09	Yes	No	0	9	9
27	R:R:K57	R:R:N60	9.79	No	No	0	5	9
28	R:R:D336	R:R:K57	4.15	No	No	0	7	5
29	R:R:D120	R:R:T59	7.23	Yes	No	0	9	8
30	R:R:F337	R:R:N60	4.83	Yes	No	0	9	9
31	R:R:F141	R:R:F61	5.36	No	No	4	3	4
32	R:R:F62	R:R:V116	5.24	Yes	No	0	8	7
33	R:R:D120	R:R:F62	10.75	Yes	Yes	0	9	8
34	R:R:A140	R:R:F62	4.16	No	Yes	0	7	8
35	R:R:F62	R:R:L143	4.87	Yes	No	0	8	7
36	R:R:F62	R:R:I144	3.77	Yes	No	0	8	8
37	R:R:N113	R:R:S65	10.43	No	No	0	8	9
38	R:R:I144	R:R:S65	7.74	No	No	0	8	9
39	R:R:D70	R:R:L66	5.43	Yes	Yes	2	9	9
40	R:R:L66	R:R:N113	4.12	Yes	No	0	9	8
41	R:R:L114	R:R:L66	5.54	No	Yes	2	9	9
42	R:R:L66	R:R:N327	6.87	Yes	Yes	2	9	9
43	R:R:S69	R:R:W148	3.71	No	Yes	0	8	9
44	R:R:D70	R:R:S110	5.89	Yes	No	0	9	9
45	R:R:D70	R:R:S324	11.78	Yes	No	0	9	9
46	R:R:D70	R:R:N327	8.08	Yes	Yes	2	9	9
47	R:R:S324	R:R:V73	8.08	No	No	0	9	8
48	R:R:F102	R:R:L76	9.74	No	No	0	5	6
49	R:R:V77	R:R:W99	4.9	No	Yes	1	8	5
50	R:R:D103	R:R:V77	4.38	Yes	No	1	7	8
51	R:R:V77	R:R:W321	8.58	No	Yes	1	8	7
52	R:R:M78	R:R:W321	6.98	No	Yes	0	7	7
53	R:R:P79	R:R:W80	5.4	No	Yes	0	8	5
54	R:R:F92	R:R:W80	7.02	Yes	Yes	1	6	5
55	R:R:F95	R:R:W80	10.02	Yes	Yes	1	5	5
56	R:R:W80	R:R:W99	7.5	Yes	Yes	1	5	5
57	R:R:E85	R:R:K81	4.05	No	Yes	1	4	6
58	R:R:D314	R:R:K81	5.53	No	Yes	1	4	6
59	R:R:K81	R:R:W318	9.28	Yes	No	1	6	5
60	R:R:K81	R:R:W321	5.8	Yes	Yes	1	6	7
61	R:R:K81	W:W:?1	8.63	Yes	Yes	1	6	0
62	R:R:P91	R:R:V83	3.53	No	No	1	1	4
63	R:R:F92	R:R:V83	7.87	Yes	No	1	6	4
64	R:R:A84	R:R:W90	3.89	No	Yes	0	5	8
65	R:R:D314	R:R:E85	9.09	No	No	1	4	4
66	R:R:F89	R:R:N185	3.62	No	No	0	4	4
67	R:R:P91	R:R:W90	4.05	No	Yes	1	1	8
68	R:R:F92	R:R:W90	15.03	Yes	Yes	1	6	8
69	R:R:C96	R:R:W90	9.14	No	Yes	0	9	8
70	R:R:W90	R:R:W99	7.5	Yes	Yes	1	8	5
71	R:R:F92	R:R:P91	14.45	Yes	No	1	6	1
72	R:R:F92	R:R:F95	5.36	Yes	Yes	1	6	5
73	R:R:F95	R:R:I98	3.77	Yes	No	0	5	6
74	R:R:F95	R:R:W99	4.01	Yes	Yes	1	5	5
75	R:R:C186	R:R:C96	7.28	No	No	0	9	9
76	R:R:K165	R:R:N97	8.39	Yes	No	0	3	6
77	R:R:F102	R:R:I98	3.77	No	No	0	5	6
78	R:R:I98	R:R:Q160	4.12	No	No	0	6	5
79	R:R:V100	R:R:W99	3.68	No	Yes	0	5	5
80	R:R:W99	W:W:?1	8.52	Yes	Yes	1	5	0
81	R:R:H164	R:R:V100	4.15	Yes	No	0	5	5
82	R:R:A101	R:R:F156	8.32	No	No	0	6	5
83	R:R:A101	R:R:V159	5.09	No	No	0	6	5
84	R:R:F102	R:R:F156	6.43	No	No	0	5	5
85	R:R:D103	R:R:W321	12.28	Yes	Yes	1	7	7
86	R:R:D103	W:W:?1	4.61	Yes	Yes	1	7	0
87	R:R:I104	R:R:S155	6.19	No	No	0	6	7
88	R:R:I104	R:R:Y194	3.63	No	Yes	0	6	7
89	R:R:M105	R:R:V152	6.09	No	No	0	5	4
90	R:R:M105	R:R:S155	4.6	No	No	0	5	7
91	R:R:F156	R:R:M105	7.46	No	No	0	5	5
92	R:R:S107	R:R:W285	4.94	No	Yes	0	7	8
93	R:R:S151	R:R:T108	4.8	No	No	0	8	6
94	R:R:S202	R:R:T108	9.59	No	No	0	6	6
95	R:R:A109	R:R:W148	7.78	No	Yes	0	7	9
96	R:R:I111	R:R:W285	17.62	No	Yes	0	8	8
97	R:R:N113	R:R:W148	4.52	No	Yes	0	8	9
98	R:R:L114	R:R:N327	9.61	No	Yes	2	9	9
99	R:R:L114	R:R:Y331	9.38	No	Yes	2	9	9
100	R:R:C115	R:R:P206	3.77	No	Yes	0	7	9
101	R:R:C115	R:R:I209	6.55	No	No	0	7	6
102	R:R:I117	R:R:R121	5.01	No	No	2	9	9
103	R:R:I117	R:R:Y331	4.84	No	Yes	2	9	9
104	R:R:M210	R:R:S118	9.2	No	No	0	8	8
105	R:R:S118	R:R:Y214	7.63	No	Yes	0	8	9
106	R:R:V119	R:R:W123	4.9	No	No	0	6	4
107	R:R:D120	R:R:Y131	9.2	Yes	No	3	9	7
108	R:R:D120	R:R:M135	4.16	Yes	No	3	9	7
109	R:R:R121	R:R:Y331	6.17	No	Yes	2	9	9
110	R:R:W123	R:R:Y122	4.82	No	Yes	0	4	8
111	R:R:S126	R:R:Y122	13.99	No	Yes	0	7	8
112	R:R:T213	R:R:Y122	4.99	No	Yes	0	7	8
113	R:R:R216	R:R:Y122	11.32	No	Yes	0	5	8
114	R:R:I217	R:R:Y122	3.63	No	Yes	0	9	8
115	R:R:M135	R:R:W123	3.49	No	No	0	7	4
116	R:R:A124	R:R:Y131	8.01	No	No	0	8	7
117	R:R:R130	R:R:S127	14.5	No	No	0	5	6
118	R:R:R130	R:R:R133	5.33	No	No	5	5	4
119	R:R:M135	R:R:Y131	9.58	No	No	3	7	7
120	R:R:I157	R:R:P158	5.08	No	No	0	6	6
121	R:R:P158	R:R:Y194	5.56	No	Yes	0	6	7
122	R:R:H164	R:R:V159	9.69	Yes	No	0	5	5
123	R:R:L161	R:R:W163	4.56	No	No	0	4	6
124	R:R:H164	R:R:K165	14.41	Yes	Yes	0	5	3
125	R:R:H164	R:R:L190	3.86	Yes	No	0	5	4
126	R:R:H164	R:R:Y194	4.36	Yes	Yes	0	5	7
127	R:R:K165	R:R:S188	7.65	Yes	No	0	3	5
128	R:R:S189	W:W:?1	4.08	No	Yes	0	4	0
129	R:R:L190	R:R:N292	5.49	No	Yes	1	4	6
130	R:R:F297	R:R:R192	6.41	No	No	0	6	4
131	R:R:S198	R:R:Y194	7.63	No	Yes	0	7	7
132	R:R:A195	R:R:P296	3.74	No	No	0	5	5
133	R:R:F289	R:R:S199	6.61	Yes	No	0	7	7
134	R:R:N292	R:R:S199	5.96	Yes	No	0	6	7
135	R:R:V200	R:R:Y204	5.05	No	No	0	4	5
136	R:R:F203	R:R:Y204	9.28	Yes	No	0	8	5
137	R:R:F203	R:R:V207	10.49	Yes	No	1	8	7
138	R:R:F203	R:R:F281	6.43	Yes	Yes	1	8	9
139	R:R:F203	R:R:W285	4.01	Yes	Yes	1	8	8
140	R:R:F203	R:R:L286	4.87	Yes	Yes	0	8	6
141	R:R:F203	R:R:F289	21.43	Yes	Yes	1	8	7
142	R:R:C293	R:R:Y204	4.03	No	No	0	6	5
143	R:R:F281	R:R:V207	3.93	Yes	No	1	9	7
144	R:R:M210	R:R:M278	4.33	No	No	0	8	8
145	R:R:F281	R:R:M210	11.2	Yes	No	0	9	8
146	R:R:R216	R:R:V212	5.23	No	No	0	5	4
147	R:R:L274	R:R:Y214	4.69	No	Yes	0	8	9
148	R:R:I277	R:R:Y214	3.63	No	Yes	0	8	9
149	R:R:M278	R:R:Y214	5.99	No	Yes	0	8	9
150	R:R:R219	R:R:T215	5.17	No	No	0	4	3
151	R:R:Q222	R:R:Y218	12.4	No	Yes	0	6	7
152	R:R:L274	R:R:Y218	3.52	No	Yes	0	8	7
153	R:R:Q222	R:R:R226	5.84	No	No	0	6	5
154	R:R:E267	R:R:Q222	14.02	No	No	0	8	6
155	R:R:I225	R:R:R266	7.52	No	No	0	5	6
156	R:R:E267	R:R:I225	6.83	No	No	0	8	5
157	R:R:I228	R:R:R266	6.26	No	No	0	7	6
158	R:R:A230	R:R:R233	5.53	No	No	0	4	1
159	R:R:C241	R:R:H237	5.9	No	No	0	1	1
160	R:R:K265	R:R:K269	5.75	No	No	0	5	8
161	R:R:K269	R:R:K272	7.18	No	No	0	8	7
162	R:R:K269	R:R:T273	6.01	No	No	0	8	9
163	R:R:I330	R:R:V280	4.61	No	No	0	8	7
164	R:R:F281	R:R:W285	7.02	Yes	Yes	1	9	8
165	R:R:L286	R:R:V282	4.47	Yes	No	0	6	7
166	R:R:C284	R:R:N323	9.45	No	No	0	9	9
167	R:R:F288	R:R:W285	6.01	Yes	Yes	1	7	8
168	R:R:F289	R:R:W285	6.01	Yes	Yes	1	7	8
169	R:R:G320	R:R:W285	8.44	No	Yes	0	7	8
170	R:R:N323	R:R:W285	10.17	No	Yes	0	9	8
171	R:R:F316	R:R:P287	8.67	Yes	No	0	5	9
172	R:R:F288	R:R:F289	8.57	Yes	Yes	1	7	7
173	R:R:F288	R:R:N292	3.62	Yes	Yes	1	7	6
174	R:R:F288	R:R:F313	4.29	Yes	No	0	7	4
175	R:R:F288	R:R:V317	3.93	Yes	No	0	7	6
176	R:R:F316	R:R:L291	4.87	Yes	No	0	5	5
177	R:R:I308	R:R:L295	7.14	No	No	0	4	3
178	R:R:I308	R:R:T312	9.12	No	No	0	4	4
179	R:R:D309	R:R:N311	5.39	No	No	0	4	1
180	R:R:D309	R:R:T312	8.67	No	No	0	4	4
181	R:R:F316	R:R:T312	3.89	Yes	No	0	5	4
182	R:R:F313	W:W:?1	5.8	No	Yes	0	4	0
183	R:R:D314	W:W:?1	10.15	No	Yes	1	4	0
184	R:R:F319	R:R:V315	3.93	No	No	0	7	4
185	R:R:W318	R:R:W321	8.43	No	Yes	1	5	7
186	R:R:N323	R:R:N327	10.9	No	Yes	0	9	9
187	R:R:N327	R:R:Y331	3.49	Yes	Yes	2	9	9
188	R:R:I330	R:R:Y331	4.84	No	Yes	0	8	9
189	R:R:F333	R:R:R338	6.41	No	No	0	8	8
190	R:R:F333	R:R:F341	5.36	No	Yes	0	8	7
191	R:R:F337	R:R:F341	9.65	Yes	Yes	0	9	7
192	R:R:G40	R:R:L39	3.42	No	No	0	9	4
193	R:R:C106	R:R:V73	3.42	No	No	0	7	8
194	R:R:A67	R:R:V44	3.39	No	Yes	0	9	9
195	R:R:A332	R:R:V44	3.39	No	Yes	0	6	9
196	R:R:N185	R:R:W90	3.39	No	Yes	0	4	8
197	R:R:I111	R:R:P206	3.39	No	Yes	0	8	9
198	R:R:I205	R:R:P206	3.39	No	Yes	0	5	9
199	R:R:A221	R:R:V270	3.39	No	No	0	9	8
200	R:R:A74	R:R:T37	3.36	No	No	0	7	7
201	R:R:L112	R:R:P206	3.28	No	Yes	0	5	9
202	R:R:L286	R:R:P287	3.28	Yes	No	0	6	9
203	R:R:C293	R:R:I196	3.27	No	No	0	6	6
204	R:R:A27	R:R:I86	3.25	No	No	0	6	5
205	R:R:S191	R:R:T193	3.2	No	No	0	5	4
206	R:R:A322	R:R:L33	3.15	No	No	0	4	7
207	R:R:I220	R:R:S126	3.1	No	No	0	6	7
208	R:R:I154	R:R:S155	3.1	No	No	0	5	7
209	R:R:I154	R:R:S198	3.1	No	No	0	5	7
210	R:R:I211	R:R:V207	3.07	No	No	0	6	7
211	R:R:I225	R:R:V270	3.07	No	No	0	5	8
212	R:R:K57	R:R:S56	3.06	No	No	0	5	8
213	R:R:S310	W:W:?1	3.06	No	Yes	0	1	0
214	R:R:K339	R:R:S342	3.06	No	No	0	5	5
215	R:R:I277	R:R:T273	3.04	No	No	0	8	9
216	R:R:L35	R:R:S31	3	No	No	0	5	4
217	R:R:L33	R:R:S325	3	No	No	0	7	6
218	R:R:L271	R:R:S275	3	No	No	0	7	6
219	R:R:L72	R:R:V68	2.98	No	No	0	7	6
220	R:R:L326	R:R:V280	2.98	No	No	0	6	7
221	R:R:L71	R:R:T42	2.95	No	No	0	8	5
222	R:R:L153	R:R:T149	2.95	No	No	0	4	3
223	R:R:I125	R:R:I217	2.94	No	No	0	8	9
224	R:R:N41	R:R:T37	2.92	Yes	No	0	9	7
225	R:R:I34	R:R:L38	2.85	No	No	0	6	7
226	R:R:I290	R:R:L286	2.85	No	Yes	0	7	6
227	R:R:G93	R:R:W90	2.81	No	Yes	0	7	8
228	R:R:A340	R:R:F51	2.77	No	Yes	0	7	6
229	R:R:A140	R:R:F61	2.77	No	No	0	7	4
230	R:R:A87	R:R:F89	2.77	No	No	0	5	4
231	R:R:L112	R:R:L150	2.77	No	No	0	5	4
232	R:R:L71	R:R:N41	2.75	No	Yes	0	8	9
233	R:R:F337	R:R:V48	2.62	Yes	No	0	9	8
234	R:R:F62	R:R:V58	2.62	Yes	No	0	8	6
235	R:R:F337	R:R:V63	2.62	Yes	No	0	9	8
236	R:R:S191	R:R:Y194	2.54	No	Yes	0	5	7
237	R:R:V68	R:R:W148	2.45	No	Yes	0	6	9
238	R:R:F341	R:R:L43	2.44	Yes	No	0	7	7
239	R:R:F337	R:R:N334	2.42	Yes	No	0	9	8
240	R:R:F51	R:R:R50	2.14	Yes	No	0	6	6
241	R:R:F316	R:R:F319	2.14	Yes	No	0	5	7
242	R:R:R219	R:R:Y218	2.06	No	Yes	0	4	7
243	R:R:C307	R:R:G299	1.96	No	No	0	3	1
244	R:R:G279	R:R:V282	1.84	No	No	0	5	7
245	R:R:P128	R:R:S127	1.78	No	No	0	8	6
246	R:R:P328	R:R:V44	1.77	No	Yes	0	9	9
247	R:R:P137	R:R:T136	1.75	No	No	0	1	8
248	R:R:A166	R:R:S191	1.71	No	No	0	2	5
249	R:R:A139	R:R:T136	1.68	No	No	0	6	8
250	R:R:C28	R:R:I24	1.64	No	No	0	5	6
251	R:R:C45	R:R:I49	1.64	No	No	0	7	4
252	R:R:L295	R:R:P296	1.64	No	No	0	3	5
253	R:R:S325	R:R:S36	1.63	No	No	0	6	4
254	R:R:V276	R:R:V280	1.6	No	No	0	7	7
255	R:R:S342	R:R:T343	1.6	No	No	0	5	4
256	R:R:T26	R:R:V22	1.59	No	No	0	5	4
257	R:R:C307	R:R:L295	1.59	No	No	0	3	3
258	R:R:A46	R:R:L344	1.58	No	No	0	5	6
259	R:R:A147	R:R:L112	1.58	No	No	0	7	5
260	R:R:I142	R:R:V146	1.54	No	No	0	1	3
261	R:R:A335	R:R:D336	1.54	No	No	0	5	7
262	R:R:K165	R:R:S162	1.53	Yes	No	0	3	5
263	R:R:I86	R:R:T26	1.52	No	No	0	5	5
264	R:R:K138	R:R:T136	1.5	No	No	0	4	8
265	R:R:L72	R:R:V75	1.49	No	No	0	7	5
266	R:R:L76	R:R:V75	1.49	No	No	0	6	5
267	R:R:L344	R:R:T343	1.47	No	No	0	6	4
268	R:R:F61	R:R:P137	1.44	No	No	4	4	1
269	R:R:F141	R:R:P137	1.44	No	No	4	3	1
270	R:R:I157	R:R:L153	1.43	No	No	0	6	4
271	R:R:E232	R:R:V236	1.43	No	No	0	3	4
272	R:R:I329	R:R:L326	1.43	No	No	0	7	6
273	R:R:C298	R:R:F297	1.4	No	No	0	4	6
274	R:R:A229	R:R:R266	1.38	No	No	0	4	6
275	R:R:I220	R:R:Q224	1.37	No	No	0	6	7
276	R:R:K223	R:R:Q224	1.36	No	No	0	5	7
277	R:R:P158	R:R:W163	1.35	No	No	0	6	6
278	R:R:F20	R:R:V22	1.31	No	No	0	1	4
279	R:R:K134	R:R:R130	1.24	No	No	5	5	5
280	R:R:K134	R:R:R133	1.24	No	No	5	5	4
281	R:R:K223	R:R:R227	1.24	No	No	0	5	5
282	R:R:F29	R:R:L30	1.22	No	No	0	3	7
283	R:R:E132	R:R:F129	1.17	No	No	0	5	7
284	R:R:L271	R:R:Y218	1.17	No	Yes	0	7	7
285	R:R:E267	R:R:F264	1.17	No	No	0	8	5
286	R:R:F20	R:R:R23	1.07	No	No	0	1	5
287	R:R:F129	R:R:R133	1.07	No	No	0	7	4
288	R:R:D187	W:W:?1	0.92	No	Yes	0	5	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	12.4991	11	1	0
2	R:R:N41	5.1375	4	0	9
3	R:R:V44	3.4475	4	0	9
4	R:R:F51	3.6575	4	0	6
5	R:R:F62	5.235	6	0	8
6	R:R:L66	5.49	4	2	9
7	R:R:D70	7.582	5	2	9
8	R:R:W80	7.485	4	1	5
9	R:R:K81	6.658	5	1	6
10	R:R:W90	6.54429	7	1	8
11	R:R:F92	9.946	5	1	6
12	R:R:F95	5.79	4	1	5
13	R:R:W99	6.01833	6	1	5
14	R:R:D103	9.7	4	1	7
15	R:R:D120	7.835	4	3	9
16	R:R:Y122	7.75	5	0	8
17	R:R:W148	4.615	4	0	9
18	R:R:H164	7.294	5	0	5
19	R:R:K165	7.995	4	0	3
20	R:R:Y194	4.744	5	0	7
21	R:R:F203	9.41833	6	1	8
22	R:R:P206	3.4575	4	0	9
23	R:R:Y214	5.485	4	0	9
24	R:R:Y218	4.7875	4	0	7
25	R:R:F281	7.145	4	1	9
26	R:R:W285	8.0275	8	1	8
27	R:R:L286	3.8675	4	0	6
28	R:R:F288	6.335	6	1	7
29	R:R:F289	9.848	5	1	7
30	R:R:N292	4.7	4	1	6
31	R:R:F316	4.8925	4	0	5
32	R:R:W321	7.915	6	1	7
33	R:R:N327	7.79	5	2	9
34	R:R:Y331	5.744	5	2	9
35	R:R:F337	4.705	6	0	9
36	R:R:F341	5.37	5	0	7
37	W:W:?1	8.63889	9	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:W321	16.6323	5.42	Yes	Yes	1	0	7
2	L:L:?1	R:R:S107	36.1596	7.15	Yes	No	0	0	7
3	R:R:S107	R:R:W285	36.4387	4.94	No	Yes	0	7	8
4	R:R:N323	R:R:W285	100	10.17	No	Yes	0	9	8
5	R:R:N323	R:R:N327	98.3083	10.9	No	Yes	0	9	9
6	R:R:D70	R:R:N327	53.6872	8.08	Yes	Yes	2	9	9
7	R:R:D70	R:R:N41	54.0796	6.73	Yes	Yes	0	9	9
8	L:L:?1	R:R:F288	36.552	11.59	Yes	Yes	1	0	7
9	R:R:F288	R:R:W285	54.908	6.01	Yes	Yes	1	7	8
10	L:L:?1	R:R:F289	55.0243	6.62	Yes	Yes	1	0	7
11	R:R:F289	R:R:W285	36.8427	6.01	Yes	Yes	1	7	8
12	R:R:N41	R:R:P328	43.3538	8.15	Yes	No	0	9	9
13	R:R:P328	R:R:V44	42.133	1.77	No	Yes	0	9	9
14	R:R:F341	R:R:V44	38.4356	5.24	Yes	Yes	0	7	9
15	R:R:F337	R:R:F341	29.605	9.65	Yes	Yes	0	9	7
16	R:R:F337	R:R:L54	13.804	6.09	Yes	No	0	9	9
17	R:R:H53	R:R:L54	12.4495	10.29	No	No	0	6	9
18	R:R:F51	R:R:H53	11.0891	4.53	Yes	No	0	6	6
19	R:R:L66	R:R:N327	36.0143	6.87	Yes	Yes	2	9	9
20	R:R:L66	R:R:N113	41.9644	4.12	Yes	No	0	9	8
21	R:R:N113	R:R:S65	37.6624	10.43	No	No	0	8	9
22	R:R:I144	R:R:S65	36.5346	7.74	No	No	0	8	9
23	R:R:F62	R:R:I144	35.401	3.77	Yes	No	0	8	8
24	R:R:D120	R:R:F62	22.5475	10.75	Yes	Yes	0	9	8
25	L:L:?1	R:R:I104	25.5007	22.32	Yes	No	0	0	6
26	L:L:?1	W:W:?1	48.2807	31.98	Yes	Yes	1	0	0
27	R:R:W99	W:W:?1	45.7198	8.52	Yes	Yes	1	5	0
28	R:R:F95	R:R:W99	11.467	4.01	Yes	Yes	1	5	5
29	R:R:W90	R:R:W99	24.8583	7.5	Yes	Yes	1	8	5
30	L:L:?1	R:R:L190	14.3272	17.88	Yes	No	1	0	4
31	R:R:H164	R:R:L190	16.3736	3.86	Yes	No	0	5	4
32	R:R:I104	R:R:Y194	16.7921	3.63	No	Yes	0	6	7
33	L:L:?1	R:R:S198	19.8442	9.19	Yes	No	0	0	7
34	R:R:S198	R:R:Y194	16.5247	7.63	No	Yes	0	7	7
35	R:R:I111	R:R:W285	11.1764	17.62	No	Yes	0	8	8
36	R:R:N327	R:R:Y331	10.8828	3.49	Yes	Yes	2	9	9
37	R:R:F281	R:R:W285	58.7885	7.02	Yes	Yes	1	9	8
38	R:R:F281	R:R:M210	72.5693	11.2	Yes	No	0	9	8
39	R:R:F203	R:R:F289	19.4111	21.43	Yes	Yes	1	8	7
40	R:R:F203	R:R:F281	15.5655	6.43	Yes	Yes	1	8	9
41	R:R:M210	R:R:S118	35.5783	9.2	No	No	0	8	8
42	R:R:S118	R:R:Y214	34.09	7.63	No	Yes	0	8	9
43	R:R:M210	R:R:M278	35.5783	4.33	No	No	0	8	8
44	R:R:M278	R:R:Y214	34.09	5.99	No	Yes	0	8	9
45	R:R:D120	R:R:M135	17.6177	4.16	Yes	No	3	9	7
46	R:R:M135	R:R:W123	16.4724	3.49	No	No	0	7	4
47	R:R:W123	R:R:Y122	14.0017	4.82	No	Yes	0	4	8
48	R:R:P158	R:R:Y194	20.6813	5.56	No	Yes	0	6	7
49	R:R:I157	R:R:P158	10.3654	5.08	No	No	0	6	6
50	R:R:F203	R:R:L286	13.8622	4.87	Yes	Yes	0	8	6
51	R:R:L286	R:R:P287	10.9438	3.28	Yes	No	0	6	9
52	R:R:F316	R:R:P287	10.1997	8.67	Yes	No	0	5	9
53	R:R:L274	R:R:Y214	49.7951	4.69	No	Yes	0	8	9
54	R:R:I277	R:R:Y214	15.7951	3.63	No	Yes	0	8	9
55	R:R:L274	R:R:Y218	46.711	3.52	No	Yes	0	8	7
56	R:R:Q222	R:R:Y218	31.2037	12.4	No	Yes	0	6	7
57	R:R:E267	R:R:Q222	24.9571	14.02	No	No	0	8	6
58	R:R:E267	R:R:I225	18.9286	6.83	No	No	0	8	5
59	R:R:I277	R:R:T273	12.6472	3.04	No	No	0	8	9
60	R:R:F288	R:R:F313	13.929	4.29	Yes	No	0	7	4
61	R:R:F313	W:W:?1	13.4523	5.8	No	Yes	0	4	0
62	R:R:S191	R:R:Y194	10.3654	2.54	No	Yes	0	5	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D103	17.53	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:I104	22.32	1	Yes	No	0	6	0	1
L:L:?1	R:R:S107	7.15	1	Yes	No	0	7	0	1
L:L:?1	R:R:L190	17.88	1	Yes	No	0	4	0	1
L:L:?1	R:R:S198	9.19	1	Yes	No	0	7	0	1
L:L:?1	R:R:S202	4.08	1	Yes	No	0	6	0	1
L:L:?1	R:R:F288	11.59	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:F289	6.62	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:N292	3.73	1	Yes	Yes	0	6	0	1
L:L:?1	R:R:W321	5.42	1	Yes	Yes	0	7	0	1
L:L:?1	W:W:?1	31.98	1	Yes	Yes	0	0	0	1
R:R:V77	R:R:W99	4.9	1	No	Yes	8	5	2	2
R:R:D103	R:R:V77	4.38	1	Yes	No	7	8	1	2
R:R:V77	R:R:W321	8.58	1	No	Yes	8	7	2	1
R:R:M78	R:R:W321	6.98	0	No	Yes	7	7	2	1
R:R:D314	R:R:K81	5.53	1	No	Yes	4	6	2	2
R:R:K81	R:R:W318	9.28	1	Yes	No	6	5	2	2
R:R:K81	R:R:W321	5.8	1	Yes	Yes	6	7	2	1
R:R:K81	W:W:?1	8.63	1	Yes	Yes	6	0	2	1
R:R:W99	W:W:?1	8.52	1	Yes	Yes	5	0	2	1
R:R:D103	R:R:W321	12.28	1	Yes	Yes	7	7	1	1
R:R:D103	W:W:?1	4.61	1	Yes	Yes	7	0	1	1
R:R:I104	R:R:S155	6.19	0	No	No	6	7	1	2
R:R:I104	R:R:Y194	3.63	0	No	Yes	6	7	1	2
R:R:S107	R:R:W285	4.94	0	No	Yes	7	8	1	2
R:R:S202	R:R:T108	9.59	0	No	No	6	6	1	2
R:R:H164	R:R:L190	3.86	0	Yes	No	5	4	2	1
R:R:H164	R:R:Y194	4.36	0	Yes	Yes	5	7	2	2
R:R:S189	W:W:?1	4.08	0	No	Yes	4	0	2	1
R:R:L190	R:R:N292	5.49	1	No	Yes	4	6	1	1
R:R:S198	R:R:Y194	7.63	0	No	Yes	7	7	1	2
R:R:F289	R:R:S199	6.61	1	Yes	No	7	7	1	2
R:R:N292	R:R:S199	5.96	1	Yes	No	6	7	1	2
R:R:F203	R:R:W285	4.01	1	Yes	Yes	8	8	2	2
R:R:F203	R:R:F289	21.43	1	Yes	Yes	8	7	2	1
R:R:F288	R:R:W285	6.01	1	Yes	Yes	7	8	1	2
R:R:F289	R:R:W285	6.01	1	Yes	Yes	7	8	1	2
R:R:F288	R:R:F289	8.57	1	Yes	Yes	7	7	1	1
R:R:F288	R:R:N292	3.62	1	Yes	Yes	7	6	1	1
R:R:F288	R:R:F313	4.29	1	Yes	No	7	4	1	2
R:R:F288	R:R:V317	3.93	1	Yes	No	7	6	1	2
R:R:F313	W:W:?1	5.8	0	No	Yes	4	0	2	1
R:R:D314	W:W:?1	10.15	1	No	Yes	4	0	2	1
R:R:W318	R:R:W321	8.43	1	No	Yes	5	7	2	1
R:R:I154	R:R:S155	3.1	0	No	No	5	7	2	2
R:R:I154	R:R:S198	3.1	0	No	No	5	7	2	1
R:R:S310	W:W:?1	3.06	0	No	Yes	1	0	2	1
R:R:D187	W:W:?1	0.92	0	No	Yes	5	0	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D103	17.53	1	Yes	Yes	0	7	1	1
L:L:?1	R:R:I104	22.32	1	Yes	No	0	6	1	2
L:L:?1	R:R:S107	7.15	1	Yes	No	0	7	1	2
L:L:?1	R:R:L190	17.88	1	Yes	No	0	4	1	2
L:L:?1	R:R:S198	9.19	1	Yes	No	0	7	1	2
L:L:?1	R:R:S202	4.08	1	Yes	No	0	6	1	2
L:L:?1	R:R:F288	11.59	1	Yes	Yes	0	7	1	2
L:L:?1	R:R:F289	6.62	1	Yes	Yes	0	7	1	2
L:L:?1	R:R:N292	3.73	1	Yes	Yes	0	6	1	2
L:L:?1	R:R:W321	5.42	1	Yes	Yes	0	7	1	2
L:L:?1	W:W:?1	31.98	1	Yes	Yes	0	0	1	0
R:R:V77	R:R:W99	4.9	1	No	Yes	8	5	2	1
R:R:D103	R:R:V77	4.38	1	Yes	No	7	8	1	2
R:R:V77	R:R:W321	8.58	1	No	Yes	8	7	2	2
R:R:F95	R:R:W80	10.02	1	Yes	Yes	5	5	2	2
R:R:W80	R:R:W99	7.5	1	Yes	Yes	5	5	2	1
R:R:E85	R:R:K81	4.05	1	No	Yes	4	6	2	1
R:R:D314	R:R:K81	5.53	1	No	Yes	4	6	1	1
R:R:K81	R:R:W318	9.28	1	Yes	No	6	5	1	2
R:R:K81	R:R:W321	5.8	1	Yes	Yes	6	7	1	2
R:R:K81	W:W:?1	8.63	1	Yes	Yes	6	0	1	0
R:R:D314	R:R:E85	9.09	1	No	No	4	4	1	2
R:R:W90	R:R:W99	7.5	1	Yes	Yes	8	5	2	1
R:R:F95	R:R:W99	4.01	1	Yes	Yes	5	5	2	1
R:R:V100	R:R:W99	3.68	0	No	Yes	5	5	2	1
R:R:W99	W:W:?1	8.52	1	Yes	Yes	5	0	1	0
R:R:D103	R:R:W321	12.28	1	Yes	Yes	7	7	1	2
R:R:D103	W:W:?1	4.61	1	Yes	Yes	7	0	1	0
R:R:S189	W:W:?1	4.08	0	No	Yes	4	0	1	0
R:R:L190	R:R:N292	5.49	1	No	Yes	4	6	2	2
R:R:F288	R:R:F289	8.57	1	Yes	Yes	7	7	2	2
R:R:F288	R:R:N292	3.62	1	Yes	Yes	7	6	2	2
R:R:F288	R:R:F313	4.29	1	Yes	No	7	4	2	1
R:R:F313	W:W:?1	5.8	0	No	Yes	4	0	1	0
R:R:D314	W:W:?1	10.15	1	No	Yes	4	0	1	0
R:R:W318	R:R:W321	8.43	1	No	Yes	5	7	2	2
R:R:S310	W:W:?1	3.06	0	No	Yes	1	0	1	0
R:R:D187	W:W:?1	0.92	0	No	Yes	5	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7X2C_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.49
Number of Linked Nodes	261
Number of Links	288
Number of Hubs	37
Number of Links mediated by Hubs	152
Number of Communities	5
Number of Nodes involved in Communities	40
Number of Links involved in Communities	62

Path Summary
Number Of Nodes in MetaPath	63
Number Of Links MetaPath	62
Number of Shortest Paths	71692
Length Of Smallest Path	3
Average Path Length	13.0257
Length of Longest Path	28
Minimum Path Strength	1.12
Average Path Strength	7.64358
Maximum Path Strength	27.15
Minimum Path Correlation	0.7
Average Path Correlation	0.938781
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.55556
Average % Of Corr. Nodes	55.1654
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.9413
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	G3C
PDB Residues	L:L:?1 W:W:?1
Environment Details	Open EMBL-EBI Page
Code	G3C
Name	(1R)-6-chloranyl-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Synonyms
Identifier
Formula	C16 H16 Cl N O3
Molecular Weight	305.756
SMILES
PubChem	12668023
Formal Charge	0
Total Atoms	37
Total Chiral Atoms	1
Total Bonds	39
Total Aromatic Bonds	12


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P21728
Sequence	>7X2C_nogp_Chain_R F S V R I L T A C F L S L L I L S T L L G N T L V C A A V I R F R H L R S K V T N F F V I S L A V S D L L V A V L V M P W K A V A E I A G F W P F G S F C N I W V A F D I M C S T A S I L N L C V I S V D R Y W A I S S P F R Y E R K M T P K A A F I L I S V A W T L S V L I S F I P V Q L S W H K A N C D S S L S R T Y A I S S S V I S F Y I P V A I M I V T Y T R I Y R I A Q K Q I R R I A A L E R A A V H A K N C F K R E T K V L K T L S V I M G V F V C C W L P F F I L N C I L P F C G F C I D S N T F D V F V W F G W A N S S L N P I I Y A F N A D F R K A F S T L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	4NTJ	A	Nucleotide	P2Y	P2Y₁₂	Homo sapiens	AZD1283	-	-	2.62	2014-03-26	doi.org/10.1038/nature13083
	7AD3	D1	Ste2-like	STE2	STE2; STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-	Gi1/STE4/γ2	3.3	2020-12-09	doi.org/10.1038/s41586-020-2994-1
	7AD3 (No Gprot)	D1	Ste2-like	STE2	STE2; STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-		3.3	2020-12-09	doi.org/10.1038/s41586-020-2994-1
	7JV5	A	Amine	Dopamine	D₁	Homo sapiens	SKF81297	-	Gs/β1/γ2	3	2021-02-24	doi.org/10.1016/j.cell.2021.01.027
	7JV5 (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	SKF81297	-		3	2021-02-24	doi.org/10.1016/j.cell.2021.01.027
	7JVP	A	Amine	Dopamine	D₁	Homo sapiens	SKF83959	-	Gs/β1/γ2	2.9	2021-02-24	doi.org/10.1016/j.cell.2021.01.027
	7JVP (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	SKF83959	-		2.9	2021-02-24	doi.org/10.1016/j.cell.2021.01.027
	7JVQ	A	Amine	Dopamine	D₁	Homo sapiens	Apomorphine	-	Gs/β1/γ2	3	2021-02-24	doi.org/10.1016/j.cell.2021.01.027
	7JVQ (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Apomorphine	-		3	2021-02-24	doi.org/10.1016/j.cell.2021.01.027
	7CKW	A	Amine	Dopamine	D₁	Homo sapiens	Fenoldopam	-	Gs/β1/γ2	3.22	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CKW (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Fenoldopam	-		3.22	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CKX	A	Amine	Dopamine	D₁	Homo sapiens	A77636	-	Gs/β1/γ2	3.54	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CKX (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	A77636	-		3.54	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CKY	A	Amine	Dopamine	D₁	Homo sapiens	PW0464	-	Gs/β1/γ2	3.2	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CKY (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	PW0464	-		3.2	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CKZ	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen	Gs/β1/γ2	3.1	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CKZ (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen		3.1	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CRH	A	Amine	Dopamine	D₁	Homo sapiens	SKF83959	-	Gs/β1/γ2	3.3	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7CRH (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	SKF83959	-		3.3	2021-03-03	doi.org/10.1016/j.cell.2021.01.028
	7LJC	A	Amine	Dopamine	D₁	Homo sapiens	SKF81297	Mevidalen	Gs/β1/γ2	3	2021-03-03	doi.org/10.1038/s41422-021-00482-0
	7LJC (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	SKF81297	Mevidalen		3	2021-03-03	doi.org/10.1038/s41422-021-00482-0
	7LJD	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen	Gs/β1/γ1	3.2	2021-03-03	doi.org/10.1038/s41422-021-00482-0
	7LJD (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen		3.2	2021-03-03	doi.org/10.1038/s41422-021-00482-0
	7CMV	A	Amine	Dopamine	D₃	Homo sapiens	PD128907	-	Gi1/β1/γ2	2.7	2021-03-10	doi.org/10.1016/j.molcel.2021.01.003
	7CMV (No Gprot)	A	Amine	Dopamine	D₃	Homo sapiens	PD128907	-		2.7	2021-03-10	doi.org/10.1016/j.molcel.2021.01.003
	7JOZ	A	Amine	Dopamine	D₁	Homo sapiens	PubChem 75202022	-	Gs/β1/γ2	3.8	2021-04-14	doi.org/10.1038/s41467-021-23519-9
	7JOZ (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	PubChem 75202022	-		3.8	2021-04-14	doi.org/10.1038/s41467-021-23519-9
	7TD1	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-	Gi1/β1/γ2	3.08	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7TD1 (No Gprot)	A	Lipid	Lysophospholipid	LPA₁	Homo sapiens	LPA	-		3.08	2022-02-09	doi.org/10.1038/s41467-022-28417-2
	7QA8	D1	Ste2-like	STE2	STE2; STE2	Saccharomyces cerevisiae	Antagonist Peptide	-	-	2.7	2022-03-16	doi.org/10.1038/s41586-022-04498-3
	7QB9	D1	Ste2-like	STE2	STE2; STE2	Saccharomyces cerevisiae	-	-	-	3.1	2022-03-16	doi.org/10.1038/s41586-022-04498-3
	7QBC	D1	Ste2-like	STE2	STE2; STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-	-	3.53	2022-03-16	doi.org/10.1038/s41586-022-04498-3
	7QBI	D1	Ste2-like	STE2	STE2; STE2	Saccharomyces cerevisiae	α-factor mating pheromone	-	-	3.46	2022-03-16	doi.org/10.1038/s41586-022-04498-3
	7WU2	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/β1/γ1	2.8	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7WU2 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		2.8	2022-04-27	doi.org/10.1038/s41586-022-04580-w
	7EPT	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	Gs/β1/γ2	3	2022-05-11	doi.org/10.1038/s41586-022-04619-y
	7EPT (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		3	2022-05-11	doi.org/10.1038/s41586-022-04619-y
	7F0T	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	-	Gs/β1/γ2	3.1	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F0T (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	-		3.1	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F1O	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP; Mg	Gs/β1/γ2	3.13	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F1O (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP; Mg		3.13	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F1Z	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP	Gs/β1/γ2	3.46	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F1Z (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP		3.46	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F23	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP	Gs/β1/γ2	3.58	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F23 (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP		3.58	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F24	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP	Gs/β1/γ2	4.16	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7F24 (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	GDP		4.16	2022-06-15	doi.org/10.1126/sciadv.abo4158
	7X2D	A	Amine	Dopamine	D₁	Homo sapiens	Tavapadon	-	Gs/β1/γ2	3.3	2022-06-15	doi.org/10.1038/s41467-022-30929-w
	7X2D (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Tavapadon	-		3.3	2022-06-15	doi.org/10.1038/s41467-022-30929-w
	7X2F	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen	Gs/β1/γ2	3	2022-06-15	doi.org/10.1038/s41467-022-30929-w
	7X2F (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Dopamine	Mevidalen		3	2022-06-15	doi.org/10.1038/s41467-022-30929-w
	7X2C	A	Amine	Dopamine	D₁	Homo sapiens	Fenoldopam	Fenoldopam	Gs/β1/γ2	3.2	2022-06-29	doi.org/10.1038/s41467-022-30929-w
	7X2C (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Fenoldopam	Fenoldopam		3.2	2022-06-29	doi.org/10.1038/s41467-022-30929-w
	7W41	A	Peptide	Bombesin	BB₂	Homo sapiens	PD176252	-	-	2.95	2023-02-22	doi.org/10.1073/pnas.2216230120
	8IRR	A	Amine	Dopamine	D₁	Homo sapiens	Rotigotine	-	Gs/β1/γ2	3.2	2023-06-07	doi.org/10.1038/s41422-023-00808-0
	8IRR (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	Rotigotine	-		3.2	2023-06-07	doi.org/10.1038/s41422-023-00808-0
	8JD1	C	Aminoacid	Metabotropic Glutamate	mGlu2; mGlu3	Homo sapiens	Glutamate	-	-	3.7	2023-06-21	doi.org/10.1038/s41422-023-00830-2
	8FD1	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	-	4.25	2023-08-30	doi.org/10.1038/s41467-023-40911-9
	8JXR	A	Amine	Dopamine	D₁	Homo sapiens	LSD	-	-	3.57	2024-09-04	doi.org/10.1016/j.neuron.2024.07.003
	8JXS	A	Amine	Dopamine	D₁	Homo sapiens	PF-6142	-	-	3	2024-09-04	doi.org/10.1016/j.neuron.2024.07.003
	8X9S	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	3.49	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9S (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		3.49	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9T	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	AP503	-	chim(NtGi1-Gs)/β1/γ2	2.75	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9T (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	AP503	-		2.75	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9U	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	Metenolone	-	chim(NtGi1-Gs)/β1/γ2	2.88	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8X9U (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	Metenolone	-		2.88	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV1	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV1 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		2.98	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV2	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-	chim(NtGi1-Gs)/β1/γ2	3.53	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	9IV2 (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	5α-DHT	-		3.53	2025-02-12	doi.org/10.1016/j.cell.2025.01.006
	8ZD1	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZD1 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JF4	A	Peptide	Bombesin	BB₁	Homo sapiens	PD168368	-	-	3.6	2025-07-09	To be published
	9I52	A	Amine	Dopamine	D₁	Homo sapiens	A1IZU	-	Gs/β1/γ2	2.8	2025-07-16	doi.org/10.1021/acs.jmedchem.5c00294
	9I52 (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	A1IZU	-		2.8	2025-07-16	doi.org/10.1021/acs.jmedchem.5c00294
	9I54	A	Amine	Dopamine	D₁	Homo sapiens	PubChem 176452091	-	Gs/β1/γ2	2.72	2025-07-16	doi.org/10.1021/acs.jmedchem.5c00294
	9I54 (No Gprot)	A	Amine	Dopamine	D₁	Homo sapiens	PubChem 176452091	-		2.72	2025-07-16	doi.org/10.1021/acs.jmedchem.5c00294
	9V0U	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-	chim(NtGi1-G13)/β1/γ2	3.51	2025-07-30	doi.org/10.1016/j.bbrc.2025.152165
	9V0U (No Gprot)	B2	Adhesion	Adhesion	ADGRD1	Homo sapiens	-	-		3.51	2025-07-30	doi.org/10.1016/j.bbrc.2025.152165
	9MD1	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P	Gz/β1/γ2	3.03	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9MD1 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P		3.03	2025-08-13	doi.org/10.1126/sciadv.adu9851

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7X2C_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.