psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:D16	A:A:L12	5.43	No	Yes	0	4	2
2	A:A:D16	A:A:S13	5.89	No	No	0	4	7
3	A:A:V20	B:B:N88	5.91	No	Yes	0	3	7
4	A:A:R22	B:B:H91	3.39	No	Yes	0	5	5
5	A:A:S23	B:B:N88	7.45	No	Yes	0	7	7
6	A:A:S23	B:B:K89	4.59	No	Yes	0	7	9
7	A:A:K24	A:A:K28	8.62	No	No	0	4	4
8	A:A:I26	B:B:K89	8.72	No	Yes	0	9	9
9	A:A:E27	B:B:K89	10.8	No	Yes	0	6	9
10	A:A:D33	A:A:Q29	9.14	No	No	0	5	4
11	A:A:Q31	R:R:R129	9.35	No	No	0	4	7
12	A:A:D33	B:B:K78	11.06	No	No	0	5	8
13	A:A:K34	A:A:R38	8.66	No	No	0	4	4
14	A:A:K34	B:B:L55	4.23	No	No	0	4	6
15	A:A:R42	A:A:Y37	18.52	No	No	0	9	4
16	A:A:Y37	B:B:L55	5.86	No	No	0	4	6
17	A:A:Y37	B:B:A56	4	No	No	0	4	7
18	A:A:H220	A:A:T40	6.85	Yes	No	0	7	7
19	A:A:F219	A:A:H41	6.79	Yes	Yes	0	8	6
20	A:A:H41	A:A:T242	9.58	Yes	No	2	6	8
21	A:A:H41	A:A:I383	3.98	Yes	Yes	2	6	8
22	A:A:H41	R:R:L123	9	Yes	Yes	0	6	5
23	A:A:I245	A:A:L43	4.28	No	No	0	7	7
24	A:A:L44	A:A:L46	8.3	No	No	0	9	8
25	A:A:F238	A:A:L44	17.05	Yes	No	0	9	9
26	A:A:I244	A:A:L44	4.28	No	No	0	8	9
27	A:A:K53	A:A:L45	7.05	No	No	0	9	8
28	A:A:L45	A:A:M221	5.65	No	No	0	8	8
29	A:A:D223	A:A:L45	6.79	No	No	0	9	8
30	A:A:G47	A:A:K53	3.49	No	No	0	9	9
31	A:A:D49	A:A:N50	4.04	No	Yes	13	8	9
32	A:A:D49	A:A:R265	9.53	No	Yes	13	8	9
33	A:A:D249	A:A:N50	12.12	No	Yes	0	8	9
34	A:A:D252	A:A:N50	5.39	No	Yes	13	8	9
35	A:A:N50	A:A:R265	12.05	Yes	Yes	13	9	9
36	A:A:S51	A:A:V247	6.46	No	Yes	0	9	7
37	A:A:G52	A:A:T55	3.64	No	No	0	9	9
38	A:A:G52	A:A:K293	3.49	No	Yes	0	9	9
39	A:A:K53	A:A:V247	4.55	No	Yes	0	9	7
40	A:A:K58	A:A:T55	4.5	No	No	0	9	9
41	A:A:S366	A:A:T55	9.59	No	No	0	9	9
42	A:A:I56	A:A:V247	4.61	No	Yes	10	7	7
43	A:A:I56	A:A:N292	4.25	No	Yes	10	7	9
44	A:A:T210	A:A:V57	4.76	No	No	0	7	7
45	A:A:K58	A:A:Q59	4.07	No	No	0	9	9
46	A:A:Q59	A:A:Y63	4.51	No	No	0	9	9
47	A:A:F212	A:A:M60	7.46	No	No	0	9	9
48	A:A:A372	A:A:M60	3.22	No	No	0	8	9
49	A:A:R61	A:A:T210	6.47	No	No	0	8	7
50	A:A:H64	A:A:Y63	8.71	No	No	0	8	9
51	A:A:T369	A:A:Y63	7.49	No	No	0	9	9
52	A:A:A372	A:A:H64	4.39	No	No	0	8	8
53	A:A:S205	A:A:V202	3.23	No	No	0	7	6
54	A:A:G206	B:B:N119	5.09	No	No	0	8	9
55	A:A:F222	A:A:I207	3.77	Yes	No	1	7	9
56	A:A:I207	B:B:W99	4.7	No	Yes	1	9	9
57	A:A:D223	A:A:F208	8.36	No	No	0	9	5
58	A:A:F208	A:A:G225	4.52	No	No	0	5	9
59	A:A:E209	A:A:K211	9.45	No	No	1	9	4
60	A:A:E209	A:A:H220	16	No	Yes	1	9	7
61	A:A:E209	A:A:F222	5.83	No	Yes	1	9	7
62	A:A:H220	A:A:K211	18.34	Yes	No	1	7	4
63	A:A:F212	A:A:F219	13.93	No	Yes	0	9	8
64	A:A:N218	A:A:Q213	5.28	No	No	0	4	3
65	A:A:D215	A:A:V214	4.38	No	No	14	5	6
66	A:A:R373	A:A:V214	5.23	Yes	No	14	5	6
67	A:A:F376	A:A:V214	10.49	Yes	No	14	8	6
68	A:A:D215	A:A:R373	11.91	No	Yes	14	5	5
69	A:A:D215	A:A:F376	3.58	No	Yes	14	5	8
70	A:A:K216	R:R:R124	3.71	No	No	0	4	4
71	A:A:V217	R:R:R124	3.92	No	No	0	5	4
72	A:A:F219	A:A:F376	4.29	Yes	Yes	0	8	8
73	A:A:C379	A:A:F219	4.19	No	Yes	0	8	8
74	A:A:F222	A:A:H220	7.92	Yes	Yes	1	7	7
75	A:A:F222	B:B:W99	22.05	Yes	Yes	1	7	9
76	A:A:V224	A:A:W234	14.71	No	Yes	0	9	9
77	A:A:Q227	A:A:W234	7.67	No	Yes	1	9	9
78	A:A:Q227	B:B:N119	5.28	No	No	0	9	9
79	A:A:Q227	B:B:Y145	6.76	No	Yes	1	9	8
80	A:A:E230	A:A:R228	3.49	Yes	No	1	9	9
81	A:A:R228	B:B:T164	3.88	No	No	0	9	6
82	A:A:R228	B:B:D186	10.72	No	Yes	1	9	9
83	A:A:E230	A:A:R232	22.1	Yes	No	1	9	8
84	A:A:E230	A:A:K233	4.05	Yes	Yes	1	9	9
85	A:A:E230	B:B:D186	11.69	Yes	Yes	1	9	9
86	A:A:R231	A:A:W234	12	No	Yes	0	9	9
87	A:A:D272	A:A:R231	3.57	No	No	0	8	9
88	A:A:I276	A:A:R231	7.52	No	No	0	8	9
89	A:A:K233	A:A:R232	4.95	Yes	No	1	9	8
90	A:A:K233	B:B:Y145	3.58	Yes	Yes	1	9	8
91	A:A:K233	B:B:M188	8.64	Yes	No	1	9	8
92	A:A:K233	B:B:C204	4.85	Yes	Yes	1	9	7
93	A:A:K233	B:B:D228	8.3	Yes	Yes	1	9	9
94	A:A:K233	B:B:N230	5.6	Yes	No	1	9	9
95	A:A:I235	A:A:W234	3.52	No	Yes	1	9	9
96	A:A:F238	A:A:W234	4.01	Yes	Yes	0	9	9
97	A:A:W234	B:B:Y145	5.79	Yes	Yes	1	9	8
98	A:A:I235	A:A:N279	4.25	No	No	1	9	8
99	A:A:I235	A:A:L282	5.71	No	No	1	9	9
100	A:A:Q236	A:A:W281	15.33	No	Yes	0	8	5
101	A:A:C237	B:B:Y59	6.72	No	Yes	0	8	8
102	A:A:F238	A:A:V241	5.24	Yes	No	0	9	9
103	A:A:F238	B:B:W99	14.03	Yes	Yes	0	9	9
104	A:A:D240	A:A:N239	4.04	No	No	1	6	8
105	A:A:N239	B:B:K57	4.2	No	Yes	1	8	9
106	A:A:N239	B:B:W332	5.65	No	Yes	1	8	9
107	A:A:D240	B:B:K57	6.91	No	Yes	1	6	9
108	A:A:C379	A:A:T242	5.07	No	No	0	8	8
109	A:A:I383	A:A:T242	4.56	Yes	No	2	8	8
110	A:A:A243	A:A:I288	3.25	No	No	0	8	9
111	A:A:I244	A:A:L282	4.28	No	No	0	8	9
112	A:A:I244	A:A:I285	4.42	No	No	0	8	7
113	A:A:I245	A:A:I375	4.42	No	No	0	7	9
114	A:A:F246	A:A:F273	5.36	No	Yes	0	9	9
115	A:A:N292	A:A:V247	4.43	Yes	Yes	10	9	7
116	A:A:L291	A:A:V248	4.47	No	No	0	8	7
117	A:A:F345	A:A:V248	6.55	No	No	0	8	7
118	A:A:D249	A:A:S251	5.89	No	No	0	8	9
119	A:A:D249	A:A:K293	16.59	No	Yes	0	8	9
120	A:A:Q294	A:A:S250	4.33	Yes	No	9	6	6
121	A:A:L297	A:A:S250	6.01	Yes	No	9	8	6
122	A:A:I341	A:A:S250	7.74	No	No	0	8	6
123	A:A:L296	A:A:S251	6.01	No	No	0	6	9
124	A:A:D252	A:A:R265	8.34	No	Yes	13	8	9
125	A:A:L297	A:A:Y253	4.69	Yes	Yes	0	8	8
126	A:A:K300	A:A:Y253	7.17	No	Yes	0	9	8
127	A:A:I308	A:A:Y253	13.3	No	Yes	0	7	8
128	A:A:Y253	A:A:Y311	4.96	Yes	No	0	8	6
129	A:A:E268	A:A:R265	6.98	No	Yes	0	9	9
130	A:A:F312	A:A:L266	6.09	No	No	0	8	8
131	A:A:I341	A:A:L266	5.71	No	No	0	8	8
132	A:A:L270	A:A:Q267	6.65	No	No	0	6	4
133	A:A:N271	A:A:Q267	5.28	No	No	0	5	4
134	A:A:D272	A:A:E268	6.5	No	No	0	8	9
135	A:A:E344	A:A:L270	6.63	No	No	0	5	6
136	A:A:F345	A:A:L270	10.96	No	No	0	8	6
137	A:A:F273	A:A:V287	3.93	Yes	No	0	9	6
138	A:A:F273	A:A:F345	6.43	Yes	No	0	9	8
139	A:A:F273	A:A:I348	6.28	Yes	No	0	9	4
140	A:A:K274	A:A:N278	4.2	No	No	0	5	8
141	A:A:I348	A:A:K274	10.18	No	No	0	4	5
142	A:A:N278	A:A:W277	4.52	No	Yes	0	8	6
143	A:A:V287	A:A:W277	4.9	No	Yes	0	6	6
144	A:A:S349	A:A:W277	4.94	Yes	Yes	0	7	6
145	A:A:H357	A:A:W277	26.45	No	Yes	0	7	6
146	A:A:N279	A:A:W281	3.39	No	Yes	1	8	5
147	A:A:L282	A:A:N279	8.24	No	No	1	9	8
148	A:A:W281	B:B:D290	3.35	Yes	Yes	1	5	6
149	A:A:W281	B:B:R314	10	Yes	Yes	1	5	8
150	A:A:W281	B:B:W332	3.75	Yes	Yes	1	5	9
151	A:A:I382	A:A:S286	9.29	No	No	0	6	8
152	A:A:F290	A:A:I288	3.77	Yes	No	0	9	9
153	A:A:D378	A:A:I288	13.99	No	No	0	7	9
154	A:A:C359	A:A:L289	4.76	No	No	0	5	9
155	A:A:L289	A:A:P361	8.21	No	No	0	9	5
156	A:A:F290	A:A:H362	6.79	Yes	No	0	9	9
157	A:A:F290	A:A:T364	9.08	Yes	Yes	10	9	9
158	A:A:F290	A:A:N371	6.04	Yes	Yes	10	9	9
159	A:A:F290	A:A:I375	5.02	Yes	No	0	9	9
160	A:A:F363	A:A:L291	6.09	Yes	No	0	5	8
161	A:A:K293	A:A:N292	5.6	Yes	Yes	0	9	9
162	A:A:N292	A:A:T364	5.85	Yes	Yes	10	9	9
163	A:A:N292	A:A:S366	4.47	Yes	No	0	9	9
164	A:A:K293	A:A:L296	4.23	Yes	No	0	9	6
165	A:A:L297	A:A:Q294	6.65	Yes	Yes	9	8	6
166	A:A:K338	A:A:Q294	8.14	Yes	Yes	9	5	6
167	A:A:F363	A:A:Q294	11.71	Yes	Yes	9	5	6
168	A:A:D295	A:A:L296	6.79	No	No	0	9	6
169	A:A:C365	A:A:D295	4.67	No	No	0	8	9
170	A:A:D331	A:A:L302	5.43	No	No	0	4	2
171	A:A:F315	A:A:I308	10.05	No	No	0	6	7
172	A:A:D310	A:A:Y311	9.2	No	No	0	3	6
173	A:A:F312	A:A:F340	7.5	No	Yes	0	8	7
174	A:A:F315	A:A:R336	17.1	No	No	0	6	5
175	A:A:F315	A:A:F340	15	No	Yes	0	6	7
176	A:A:P321	A:A:Y318	5.56	No	No	0	5	6
177	A:A:F340	A:A:Y318	9.28	Yes	No	0	7	6
178	A:A:D343	A:A:Y318	11.49	No	No	0	3	6
179	A:A:P321	A:A:T320	3.5	No	No	0	5	1
180	A:A:R336	A:A:T320	3.88	No	No	0	5	1
181	A:A:A324	A:A:Y339	6.67	No	Yes	0	3	3
182	A:A:P326	A:A:T335	8.74	No	No	0	1	4
183	A:A:E330	A:A:P328	4.72	Yes	No	0	3	1
184	A:A:E330	A:A:V334	7.13	Yes	No	0	3	4
185	A:A:D331	A:A:P332	3.22	No	No	0	4	1
186	A:A:K338	A:A:Y339	4.78	Yes	Yes	9	5	3
187	A:A:F363	A:A:K338	14.89	Yes	Yes	9	5	5
188	A:A:R342	A:A:Y339	8.23	Yes	Yes	9	4	3
189	A:A:F363	A:A:Y339	7.22	Yes	Yes	9	5	3
190	A:A:E344	A:A:F340	7	No	Yes	0	5	7
191	A:A:D343	A:A:R342	4.76	No	Yes	0	3	4
192	A:A:L346	A:A:R342	7.29	No	Yes	9	4	4
193	A:A:P361	A:A:R342	5.76	No	Yes	9	5	4
194	A:A:F363	A:A:R342	6.41	Yes	Yes	9	5	4
195	A:A:E344	A:A:R347	9.3	No	No	0	5	4
196	A:A:L346	A:A:S349	6.01	No	Yes	0	4	7
197	A:A:L346	A:A:P361	6.57	No	No	9	4	5
198	A:A:C359	A:A:S349	6.89	No	Yes	0	5	7
199	A:A:Y358	A:A:Y360	11.91	No	Yes	0	4	8
200	A:A:Y358	R:R:S214	3.82	No	No	0	4	3
201	A:A:D378	A:A:Y360	12.64	No	Yes	0	7	8
202	A:A:D381	A:A:Y360	9.2	No	Yes	0	8	8
203	A:A:I382	A:A:Y360	4.84	No	Yes	0	6	8
204	A:A:H362	A:A:R374	19.18	No	Yes	0	9	4
205	A:A:D378	A:A:H362	10.08	No	No	0	7	9
206	A:A:N371	A:A:T364	4.39	Yes	Yes	10	9	9
207	A:A:R374	A:A:T364	5.17	Yes	Yes	10	4	9
208	A:A:C365	A:A:D368	6.22	No	No	0	8	9
209	A:A:D368	A:A:N371	4.04	No	Yes	10	9	9
210	A:A:D368	A:A:R374	3.57	No	Yes	10	9	4
211	A:A:N371	A:A:R374	3.62	Yes	Yes	10	9	4
212	A:A:F376	A:A:R373	4.28	Yes	Yes	14	8	5
213	A:A:N377	A:A:R373	3.62	No	Yes	0	4	5
214	A:A:F376	R:R:L123	3.65	Yes	Yes	0	8	5
215	A:A:R380	R:R:P122	7.21	No	No	0	7	8
216	A:A:R380	R:R:L123	4.86	No	Yes	0	7	5
217	A:A:D381	R:R:S212	4.42	No	No	0	8	5
218	A:A:D381	R:R:S214	4.42	No	No	0	8	3
219	A:A:H387	A:A:I383	6.63	No	Yes	2	8	8
220	A:A:I383	R:R:P122	3.39	Yes	No	0	8	8
221	A:A:Q384	R:R:V119	4.3	No	No	0	6	8
222	A:A:Q384	R:R:P122	4.74	No	No	0	6	8
223	A:A:R385	A:A:R389	6.4	No	No	0	5	4
224	A:A:R385	R:R:S214	5.27	No	No	0	5	3
225	A:A:R385	R:R:E219	10.47	No	No	0	5	5
226	A:A:M386	A:A:Q390	4.08	No	No	0	3	4
227	A:A:H387	A:A:Y391	4.36	No	Yes	2	8	4
228	A:A:H387	R:R:A118	4.39	No	No	2	8	8
229	A:A:L388	A:A:L393	4.15	No	Yes	0	8	8
230	A:A:L388	A:A:L394	6.92	No	Yes	0	8	8
231	A:A:Q390	A:A:Y391	3.38	No	Yes	0	4	4
232	A:A:Q390	R:R:R50	8.18	No	No	0	4	7
233	A:A:Y391	R:R:E51	4.49	Yes	Yes	2	4	6
234	A:A:Y391	R:R:L52	4.69	Yes	Yes	2	4	7
235	A:A:Y391	R:R:D114	8.05	Yes	Yes	2	4	8
236	A:A:Y391	R:R:A118	9.34	Yes	No	2	4	8
237	A:A:E392	R:R:Q45	5.1	No	No	0	6	5
238	A:A:E392	R:R:C297	15.19	No	No	0	6	7
239	A:A:L393	R:R:R115	3.64	Yes	Yes	0	8	9
240	A:A:L393	R:R:L205	6.92	Yes	No	0	8	8
241	A:A:L394	R:R:E219	3.98	Yes	No	0	8	5
242	A:A:L394	R:R:V223	4.47	Yes	No	0	8	7
243	B:B:D5	B:B:E3	10.39	No	No	0	1	5
244	B:B:E10	B:B:Q6	5.1	No	No	0	8	1
245	B:B:L7	G:G:A12	4.73	No	No	0	8	5
246	B:B:L7	G:G:R13	3.64	No	No	0	8	6
247	B:B:L7	G:G:V16	5.96	No	No	0	8	7
248	B:B:E12	B:B:R8	3.49	No	No	0	4	3
249	B:B:K15	B:B:R19	6.19	No	No	0	6	4
250	B:B:N16	B:B:R19	6.03	No	No	0	1	4
251	B:B:D20	B:B:Q17	3.92	No	No	0	2	4
252	B:B:I18	B:B:R22	5.01	Yes	No	0	7	6
253	B:B:I18	G:G:A23	3.25	Yes	No	0	7	8
254	B:B:A21	G:G:R27	5.53	No	Yes	0	4	8
255	B:B:D258	B:B:R22	13.1	Yes	No	0	7	6
256	B:B:A26	B:B:Q259	4.55	No	No	0	3	6
257	B:B:D27	G:G:K29	9.68	No	No	0	8	4
258	B:B:D27	G:G:V30	4.38	No	No	0	8	8
259	B:B:D27	G:G:S31	8.83	No	No	0	8	9
260	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
261	B:B:L261	B:B:L30	5.54	No	No	0	5	5
262	B:B:L30	B:B:M262	4.24	No	Yes	0	5	4
263	B:B:L30	G:G:A34	4.73	No	No	0	5	6
264	B:B:I37	B:B:T34	4.56	No	No	16	2	5
265	B:B:K301	B:B:T34	7.51	Yes	No	16	5	5
266	B:B:I37	B:B:R283	5.01	No	Yes	0	2	9
267	B:B:I37	B:B:K301	5.82	No	Yes	16	2	5
268	B:B:D38	B:B:P39	3.22	No	No	0	1	1
269	B:B:I43	B:B:V40	4.61	No	No	0	3	3
270	B:B:D298	B:B:V40	8.76	No	No	0	9	3
271	B:B:G41	B:B:R42	4.5	No	No	0	1	2
272	B:B:Q44	B:B:R42	4.67	No	No	0	4	2
273	B:B:I43	B:B:L284	4.28	No	No	0	3	5
274	B:B:A305	B:B:I43	3.25	No	No	0	4	3
275	B:B:L308	B:B:M45	5.65	No	No	7	7	4
276	B:B:M45	B:B:W339	3.49	No	Yes	7	4	9
277	B:B:M45	G:G:L50	7.07	No	No	0	4	9
278	B:B:R46	B:B:R48	5.33	No	No	0	5	7
279	B:B:K337	B:B:T47	6.01	Yes	No	7	6	3
280	B:B:T47	B:B:W339	3.64	No	Yes	7	3	9
281	B:B:N340	B:B:R48	3.62	No	No	6	9	7
282	B:B:R48	G:G:F61	4.28	No	Yes	6	7	8
283	B:B:R49	B:B:T87	5.17	No	No	0	7	5
284	B:B:I338	B:B:R49	3.76	Yes	No	6	5	7
285	B:B:R49	G:G:F61	9.62	No	Yes	6	7	8
286	B:B:R52	B:B:T50	10.35	No	No	0	7	3
287	B:B:K337	B:B:T50	7.51	Yes	No	0	6	3
288	B:B:L51	B:B:W82	19.36	No	Yes	0	9	9
289	B:B:L336	B:B:L51	5.54	No	No	0	7	9
290	B:B:F335	B:B:R52	8.55	No	No	0	4	7
291	B:B:H54	B:B:I58	9.28	Yes	No	0	9	9
292	B:B:H54	B:B:S72	5.58	Yes	No	0	9	9
293	B:B:H54	B:B:S74	16.74	Yes	No	0	9	9
294	B:B:H54	B:B:I80	10.61	Yes	No	0	9	8
295	B:B:D76	B:B:L55	12.21	No	No	0	9	6
296	B:B:K57	B:B:Y59	9.55	Yes	Yes	1	9	8
297	B:B:K57	B:B:Q75	9.49	Yes	No	1	9	9
298	B:B:K57	B:B:W332	12.76	Yes	Yes	1	9	9
299	B:B:I58	B:B:L336	4.28	No	No	0	9	7
300	B:B:Q75	B:B:Y59	15.78	No	Yes	1	9	8
301	B:B:M101	B:B:Y59	4.79	No	Yes	0	9	8
302	B:B:W332	B:B:Y59	14.47	Yes	Yes	1	9	8
303	B:B:A60	B:B:C103	3.61	No	No	0	7	8
304	B:B:M61	B:B:W63	4.65	No	Yes	6	6	7
305	B:B:L70	B:B:M61	4.24	No	No	6	5	6
306	B:B:C317	B:B:M61	4.86	No	No	0	7	6
307	B:B:H62	B:B:Y105	3.27	No	Yes	0	6	6
308	B:B:H62	B:B:R150	19.18	No	No	0	6	6
309	B:B:L70	B:B:W63	11.39	No	Yes	6	5	7
310	B:B:S84	B:B:W63	4.94	No	Yes	6	5	7
311	B:B:T321	B:B:W63	10.92	No	Yes	6	7	7
312	B:B:A328	B:B:W63	3.89	No	Yes	0	5	7
313	B:B:I338	B:B:W63	3.52	Yes	Yes	6	5	7
314	B:B:G64	B:B:Y105	5.79	No	Yes	0	5	6
315	B:B:D66	B:B:R68	3.57	No	No	0	8	5
316	B:B:D66	B:B:L69	6.79	No	No	0	8	5
317	B:B:S67	B:B:T321	6.4	No	No	6	5	7
318	B:B:D323	B:B:S67	11.78	No	No	6	7	5
319	B:B:D83	B:B:R68	13.1	No	No	0	8	5
320	B:B:R68	B:B:Y85	27.78	No	No	0	5	4
321	B:B:L69	B:B:Y105	3.52	No	Yes	0	5	6
322	B:B:L70	B:B:W82	4.56	No	Yes	0	5	9
323	B:B:L79	B:B:V71	4.47	Yes	No	0	7	8
324	B:B:C103	B:B:V71	3.42	No	No	0	8	8
325	B:B:S72	B:B:W82	4.94	No	Yes	0	9	9
326	B:B:L336	B:B:S72	7.51	No	No	0	7	9
327	B:B:A73	B:B:V100	3.39	No	No	0	9	9
328	B:B:A73	B:B:C103	3.61	No	No	0	9	8
329	B:B:D76	B:B:S74	10.31	No	No	0	9	9
330	B:B:Q75	B:B:W99	6.57	No	Yes	1	9	9
331	B:B:I93	B:B:L79	5.71	Yes	Yes	8	7	7
332	B:B:L79	B:B:L95	5.54	Yes	Yes	8	7	8
333	B:B:C114	B:B:L79	6.35	Yes	Yes	8	8	7
334	B:B:I80	B:B:W82	15.27	No	Yes	0	8	9
335	B:B:I81	B:B:V90	4.61	No	No	8	7	5
336	B:B:H91	B:B:I81	7.95	Yes	No	8	5	7
337	B:B:I81	B:B:L126	4.28	No	No	0	7	5
338	B:B:K89	B:B:W82	9.28	Yes	Yes	0	9	9
339	B:B:D83	B:B:T86	11.56	No	No	0	8	6
340	B:B:I338	B:B:S84	6.19	Yes	No	6	5	5
341	B:B:S84	G:G:F61	6.61	No	Yes	6	5	8
342	B:B:Y85	G:G:P60	16.69	No	No	0	4	9
343	B:B:Y85	G:G:F61	6.19	No	Yes	0	4	8
344	B:B:N88	B:B:T86	10.24	Yes	No	0	7	6
345	B:B:H91	B:B:V90	5.54	Yes	No	8	5	5
346	B:B:H91	B:B:V133	4.15	Yes	No	8	5	4
347	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
348	B:B:I93	B:B:Y124	4.84	Yes	Yes	8	7	6
349	B:B:I93	B:B:V133	10.75	Yes	No	8	7	4
350	B:B:L95	B:B:V100	4.47	Yes	No	8	8	9
351	B:B:C114	B:B:L95	6.35	Yes	Yes	8	8	8
352	B:B:L95	B:B:Y124	5.86	Yes	Yes	8	8	6
353	B:B:R96	B:B:V135	7.85	No	No	0	6	4
354	B:B:E138	B:B:R96	8.14	No	No	0	6	6
355	B:B:D118	B:B:S97	8.83	No	No	0	9	8
356	B:B:S98	B:B:W99	7.41	No	Yes	0	8	9
357	B:B:L117	B:B:W99	4.56	No	Yes	0	9	9
358	B:B:C114	B:B:V100	3.42	Yes	No	8	8	9
359	B:B:M101	B:B:Y145	5.99	No	Yes	0	9	8
360	B:B:C148	B:B:T102	3.38	No	No	0	6	8
361	B:B:C149	B:B:T102	6.76	No	No	0	8	8
362	B:B:G109	B:B:Y105	4.35	No	Yes	0	5	6
363	B:B:V112	B:B:Y105	3.79	No	Yes	0	8	6
364	B:B:A106	B:B:F151	6.93	No	Yes	0	6	9
365	B:B:N110	B:B:S108	8.94	Yes	No	15	4	6
366	B:B:D154	B:B:S108	8.83	No	No	15	6	6
367	B:B:N110	B:B:Y111	3.49	Yes	Yes	15	4	4
368	B:B:K127	B:B:N110	9.79	No	Yes	0	4	4
369	B:B:D154	B:B:N110	5.39	No	Yes	15	6	4
370	B:B:I123	B:B:Y111	3.63	No	Yes	0	6	4
371	B:B:N125	B:B:Y111	11.63	No	Yes	0	4	4
372	B:B:D154	B:B:Y111	9.2	No	Yes	15	6	4
373	B:B:V112	B:B:Y124	3.79	No	Yes	0	8	6
374	B:B:L126	B:B:V112	4.47	No	No	0	5	8
375	B:B:C114	B:B:Y124	5.38	Yes	Yes	8	8	6
376	B:B:L117	B:B:Y145	3.52	No	Yes	0	9	8
377	B:B:D118	B:B:I120	4.2	No	No	0	9	6
378	B:B:G144	B:B:N119	5.09	No	No	0	8	9
379	B:B:C121	B:B:L139	4.76	No	Yes	0	8	9
380	B:B:C121	B:B:C149	3.64	No	No	0	8	8
381	B:B:C121	B:B:T159	3.38	No	Yes	0	8	9
382	B:B:S122	B:B:Y124	3.82	No	Yes	0	8	6
383	B:B:I123	B:B:I171	5.89	No	No	0	6	6
384	B:B:V133	B:B:Y124	3.79	No	Yes	8	4	6
385	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
386	B:B:N125	B:B:T128	5.85	No	No	0	4	3
387	B:B:R134	B:B:T128	5.17	No	No	0	3	3
388	B:B:E130	B:B:N132	5.26	No	No	17	3	3
389	B:B:E130	B:B:R134	4.65	No	No	17	3	3
390	B:B:N132	B:B:R134	6.03	No	No	17	3	3
391	B:B:L139	B:B:W169	15.94	Yes	Yes	0	9	8
392	B:B:H142	B:B:L146	3.86	Yes	No	1	9	7
393	B:B:H142	B:B:T159	6.85	Yes	Yes	1	9	9
394	B:B:H142	B:B:S161	15.34	Yes	No	1	9	9
395	B:B:D163	B:B:H142	7.56	Yes	Yes	1	9	9
396	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
397	B:B:D163	B:B:G144	3.35	Yes	No	0	9	8
398	B:B:G162	B:B:Y145	10.14	No	Yes	1	9	8
399	B:B:D186	B:B:Y145	10.34	Yes	Yes	1	9	8
400	B:B:M188	B:B:Y145	5.99	No	Yes	1	8	8
401	B:B:L146	B:B:T159	10.32	No	Yes	1	7	9
402	B:B:S147	B:B:S160	4.89	No	No	0	9	6
403	B:B:L192	B:B:R150	4.86	No	No	0	5	6
404	B:B:F151	B:B:I157	13.82	Yes	No	0	9	7
405	B:B:L152	B:B:Q156	6.65	Yes	No	0	3	5
406	B:B:L152	B:B:V158	4.47	Yes	No	0	3	5
407	B:B:L152	B:B:L192	6.92	Yes	No	0	3	5
408	B:B:L152	B:B:T196	4.42	Yes	No	0	3	1
409	B:B:D153	B:B:Q156	11.75	No	No	0	5	5
410	B:B:D170	B:B:N155	8.08	No	No	0	9	3
411	B:B:I157	B:B:W169	3.52	No	Yes	0	7	8
412	B:B:I157	B:B:I171	4.42	No	No	0	7	6
413	B:B:L190	B:B:V158	7.45	No	No	4	5	5
414	B:B:F199	B:B:V158	6.55	Yes	No	4	9	5
415	B:B:T159	B:B:W169	10.92	Yes	Yes	1	9	8
416	B:B:S160	B:B:V187	4.85	No	Yes	0	6	9
417	B:B:L190	B:B:S160	6.01	No	No	0	5	6
418	B:B:G162	B:B:S161	3.71	No	No	1	9	9
419	B:B:D163	B:B:S161	5.89	Yes	No	1	9	9
420	B:B:D186	B:B:G162	5.03	Yes	No	1	9	9
421	B:B:D163	B:B:T165	8.67	Yes	No	0	9	7
422	B:B:C166	B:B:F199	4.19	No	Yes	0	8	9
423	B:B:C166	B:B:S201	3.44	No	Yes	0	8	9
424	B:B:A167	B:B:W169	5.19	No	Yes	1	4	8
425	B:B:A167	B:B:Q176	6.06	No	Yes	1	4	4
426	B:B:Q176	B:B:W169	14.24	Yes	Yes	1	4	8
427	B:B:D170	B:B:T173	5.78	No	No	0	9	5
428	B:B:Q176	B:B:T179	8.5	Yes	No	0	4	4
429	B:B:F180	B:B:T178	7.78	Yes	No	0	7	4
430	B:B:F180	B:B:F199	10.72	Yes	Yes	4	7	9
431	B:B:F180	B:B:W211	16.04	Yes	Yes	4	7	8
432	B:B:F180	B:B:G216	4.52	Yes	No	0	7	4
433	B:B:G182	B:B:T181	3.64	No	No	0	6	2
434	B:B:H183	B:B:V187	9.69	Yes	Yes	4	9	9
435	B:B:H183	B:B:S201	5.58	Yes	Yes	4	9	9
436	B:B:A203	B:B:H183	8.78	No	Yes	4	8	9
437	B:B:D205	B:B:H183	10.08	No	Yes	0	9	9
438	B:B:H183	B:B:K209	14.41	Yes	Yes	4	9	6
439	B:B:D205	B:B:T184	4.34	No	No	0	9	3
440	B:B:S201	B:B:V187	3.23	Yes	Yes	4	9	9
441	B:B:A203	B:B:V187	5.09	No	Yes	4	8	9
442	B:B:C204	B:B:M188	3.24	Yes	No	1	7	8
443	B:B:I232	B:B:S189	6.19	No	No	0	8	7
444	B:B:F199	B:B:L190	6.09	Yes	No	4	9	5
445	B:B:F234	B:B:S191	5.28	Yes	No	0	5	8
446	B:B:A193	B:B:F234	5.55	No	Yes	0	4	5
447	B:B:G238	B:B:P194	4.06	No	No	0	7	4
448	B:B:D195	B:B:R197	15.48	No	No	0	5	5
449	B:B:L198	B:B:L210	11.07	No	No	0	3	5
450	B:B:F199	B:B:W211	13.03	Yes	Yes	4	9	8
451	B:B:L210	B:B:V200	4.47	No	Yes	0	5	6
452	B:B:I232	B:B:V200	6.14	No	Yes	5	8	6
453	B:B:F234	B:B:V200	9.18	Yes	Yes	0	5	6
454	B:B:F241	B:B:V200	7.87	Yes	Yes	5	6	6
455	B:B:S201	B:B:W211	7.41	Yes	Yes	4	9	8
456	B:B:G202	B:B:I229	3.53	No	No	0	6	7
457	B:B:C204	B:B:D228	6.22	Yes	Yes	1	7	9
458	B:B:D205	B:B:S207	10.31	No	No	0	9	5
459	B:B:K209	B:B:W211	8.12	Yes	Yes	4	6	8
460	B:B:C218	B:B:K209	6.47	Yes	Yes	4	5	6
461	B:B:K209	B:B:T221	13.51	Yes	No	0	6	7
462	B:B:L210	B:B:L255	5.54	No	No	0	5	6
463	B:B:C218	B:B:W211	5.22	Yes	Yes	4	5	8
464	B:B:D212	B:B:E215	3.9	No	No	0	9	3
465	B:B:D212	B:B:R219	14.29	No	No	0	9	5
466	B:B:E215	B:B:M217	6.77	No	No	0	3	3
467	B:B:M217	B:B:R219	12.41	No	No	0	3	5
468	B:B:C218	G:G:Q18	6.1	Yes	No	4	5	9
469	B:B:C218	G:G:E22	4.56	Yes	No	4	5	9
470	B:B:F222	B:B:Q220	7.03	Yes	No	5	8	7
471	B:B:D258	B:B:Q220	15.66	Yes	No	5	7	7
472	B:B:Q220	G:G:I25	5.49	No	No	0	7	2
473	B:B:T221	G:G:E22	8.47	No	No	0	7	9
474	B:B:F222	B:B:F241	12.86	Yes	Yes	5	8	6
475	B:B:F222	B:B:F253	11.79	Yes	Yes	5	8	6
476	B:B:D258	B:B:F222	3.58	Yes	Yes	5	7	8
477	B:B:H225	B:B:I229	9.28	Yes	No	5	9	7
478	B:B:H225	B:B:T243	8.21	Yes	Yes	5	9	8
479	B:B:H225	B:B:S245	13.95	Yes	No	5	9	9
480	B:B:D247	B:B:H225	8.82	Yes	Yes	5	9	9
481	B:B:H225	B:B:R251	20.31	Yes	Yes	0	9	8
482	B:B:D247	B:B:E226	5.2	Yes	No	0	9	3
483	B:B:D228	B:B:S227	5.89	Yes	No	0	9	6
484	B:B:D228	B:B:N230	6.73	Yes	No	1	9	9
485	B:B:D228	B:B:D246	11.98	Yes	No	1	9	9
486	B:B:I229	B:B:T243	4.56	No	Yes	5	7	8
487	B:B:D246	B:B:N230	9.42	No	No	1	9	9
488	B:B:A231	B:B:V276	3.39	No	No	0	5	6
489	B:B:F241	B:B:I232	5.02	Yes	No	5	6	8
490	B:B:C233	B:B:V276	3.42	No	No	0	3	6
491	B:B:C233	B:B:F278	4.19	No	Yes	0	3	7
492	B:B:F235	B:B:P236	13	Yes	No	12	6	7
493	B:B:F235	B:B:F278	10.72	Yes	Yes	12	6	7
494	B:B:F235	B:B:G282	4.52	Yes	No	12	6	9
495	B:B:F235	G:G:L37	10.96	Yes	No	0	6	7
496	B:B:F235	G:G:Y40	5.16	Yes	Yes	12	6	6
497	B:B:F235	G:G:C41	4.19	Yes	No	0	6	7
498	B:B:G282	B:B:P236	4.06	No	No	12	9	7
499	B:B:P236	G:G:Y40	8.34	No	Yes	12	7	6
500	B:B:N237	B:B:N239	14.98	No	No	0	5	2
501	B:B:N237	G:G:Y40	4.65	No	Yes	0	5	6
502	B:B:N239	B:B:R256	12.05	No	Yes	0	2	9
503	B:B:F241	B:B:F253	11.79	Yes	Yes	5	6	6
504	B:B:F253	B:B:T243	7.78	Yes	Yes	5	6	8
505	B:B:G244	B:B:I273	5.29	No	Yes	0	5	6
506	B:B:D247	B:B:S245	10.31	Yes	No	5	9	9
507	B:B:D247	B:B:T249	10.12	Yes	No	0	9	6
508	B:B:R251	B:B:T249	3.88	Yes	No	0	8	6
509	B:B:C250	B:B:Y264	4.03	No	Yes	0	8	5
510	B:B:C250	B:B:I273	6.55	No	Yes	0	8	6
511	B:B:E260	B:B:R251	20.93	No	Yes	0	6	8
512	B:B:R251	B:B:T263	6.47	Yes	No	0	8	1
513	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
514	B:B:E260	B:B:F253	7	No	Yes	0	6	6
515	B:B:D254	B:B:R256	4.76	No	Yes	0	9	9
516	B:B:A257	B:B:D254	4.63	No	No	0	7	9
517	B:B:R256	G:G:I28	8.77	Yes	No	0	9	4
518	B:B:R256	G:G:D36	7.15	Yes	No	0	9	5
519	B:B:D258	G:G:R27	7.15	Yes	Yes	0	7	8
520	B:B:M262	B:B:Y264	7.18	Yes	Yes	0	4	5
521	B:B:A302	B:B:M262	3.22	No	Yes	0	2	4
522	B:B:L285	B:B:Y264	4.69	Yes	Yes	0	6	5
523	B:B:W297	B:B:Y264	6.75	No	Yes	0	8	5
524	B:B:H266	B:B:N268	6.38	No	No	0	4	4
525	B:B:H266	B:B:I269	3.98	No	No	0	4	4
526	B:B:I269	B:B:Y289	6.04	No	Yes	0	4	7
527	B:B:C271	B:B:Y289	4.03	Yes	Yes	1	5	7
528	B:B:C271	B:B:D290	4.67	Yes	Yes	1	5	6
529	B:B:C271	B:B:D291	7.78	Yes	No	1	5	8
530	B:B:I273	B:B:V276	4.61	Yes	No	0	6	6
531	B:B:A287	B:B:I273	3.25	No	Yes	0	6	6
532	B:B:D290	B:B:T274	7.23	Yes	No	1	6	8
533	B:B:R314	B:B:T274	5.17	Yes	No	1	8	8
534	B:B:L318	B:B:S275	6.01	No	No	0	6	8
535	B:B:S277	B:B:V320	4.85	No	No	0	5	7
536	B:B:F278	B:B:G282	6.02	Yes	No	12	7	9
537	B:B:F278	B:B:L285	9.74	Yes	Yes	0	7	6
538	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
539	B:B:S279	G:G:L50	6.01	No	No	0	9	9
540	B:B:G324	B:B:K280	3.49	No	No	0	9	1
541	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
542	B:B:D298	B:B:R283	15.48	No	Yes	0	9	9
543	B:B:L300	B:B:R283	8.5	No	Yes	0	6	9
544	B:B:R283	G:G:L51	6.07	Yes	Yes	0	9	6
545	B:B:L284	B:B:V296	5.96	No	No	0	5	5
546	B:B:L284	G:G:L51	4.15	No	Yes	0	5	6
547	B:B:L286	B:B:V327	5.96	No	No	0	7	6
548	B:B:A287	B:B:Y289	4	No	Yes	0	6	7
549	B:B:C294	B:B:G288	3.92	No	No	7	5	7
550	B:B:G288	B:B:V315	3.68	No	Yes	7	7	7
551	B:B:D291	B:B:Y289	3.45	No	Yes	1	8	7
552	B:B:N295	B:B:Y289	10.47	Yes	Yes	1	6	7
553	B:B:W297	B:B:Y289	7.72	No	Yes	1	8	7
554	B:B:D290	B:B:R314	13.1	Yes	Yes	1	6	8
555	B:B:F292	B:B:N313	3.62	No	No	0	4	7
556	B:B:N293	B:B:V307	4.43	No	No	0	5	3
557	B:B:A309	B:B:N293	6.25	No	No	0	3	5
558	B:B:C294	B:B:V315	5.12	No	Yes	7	5	7
559	B:B:C294	B:B:T329	5.07	No	Yes	7	5	8
560	B:B:N295	B:B:W297	4.52	Yes	No	1	6	8
561	B:B:N295	B:B:R304	14.46	Yes	No	0	6	5
562	B:B:N295	B:B:V307	4.43	Yes	No	0	6	3
563	B:B:D298	B:B:K301	6.91	No	Yes	0	9	5
564	B:B:L300	G:G:C41	6.35	No	No	0	6	7
565	B:B:D303	B:B:K301	4.15	No	Yes	0	2	5
566	B:B:L308	B:B:W339	21.64	No	Yes	7	7	9
567	B:B:H311	B:B:V315	4.15	Yes	Yes	7	9	7
568	B:B:H311	B:B:T329	6.85	Yes	Yes	7	9	8
569	B:B:H311	B:B:S331	16.74	Yes	No	7	9	9
570	B:B:D333	B:B:H311	8.82	Yes	Yes	7	9	9
571	B:B:H311	B:B:K337	10.48	Yes	Yes	7	9	6
572	B:B:D312	B:B:D333	5.32	No	Yes	0	5	9
573	B:B:N313	B:B:W332	4.52	No	Yes	0	7	9
574	B:B:R314	B:B:W332	27.99	Yes	Yes	1	8	9
575	B:B:T329	B:B:V315	4.76	Yes	Yes	7	8	7
576	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
577	B:B:D323	B:B:T321	7.23	No	No	6	7	7
578	B:B:D323	B:B:M325	8.32	No	No	0	7	5
579	B:B:G324	G:G:P49	4.06	No	No	0	9	7
580	B:B:M325	G:G:P49	6.71	No	No	0	5	7
581	B:B:M325	G:G:P60	3.35	No	No	0	5	9
582	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
583	B:B:V327	G:G:L50	4.47	No	No	0	6	9
584	B:B:T329	B:B:W339	4.85	Yes	Yes	7	8	9
585	B:B:D333	B:B:S331	8.83	Yes	No	7	9	9
586	B:B:D333	B:B:F335	9.55	Yes	No	0	9	4
587	B:B:F335	B:B:S334	3.96	No	No	0	4	4
588	B:B:K337	B:B:W339	8.12	Yes	Yes	7	6	9
589	B:B:I338	G:G:F61	6.28	Yes	Yes	6	5	8
590	B:B:N340	G:G:N59	6.81	No	No	0	9	9
591	B:B:N340	G:G:F61	4.83	No	Yes	6	9	8
592	G:G:E17	G:G:R13	3.49	No	No	0	6	6
593	G:G:E22	G:G:Q18	15.29	No	No	4	9	9
594	G:G:K20	G:G:M21	4.32	No	No	0	6	1
595	G:G:I25	G:G:R27	7.52	No	Yes	0	2	8
596	G:G:I28	G:G:K32	14.54	No	No	0	4	5
597	G:G:D36	G:G:K32	4.15	No	No	0	5	5
598	G:G:E42	G:G:M38	5.41	No	No	0	1	4
599	G:G:H44	G:G:Y40	21.78	No	Yes	0	6	6
600	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
601	G:G:D48	G:G:L51	8.14	Yes	Yes	0	9	6
602	G:G:P55	G:G:V54	5.3	No	No	0	5	6
603	R:R:H165	R:R:S13	5.58	Yes	No	0	3	5
604	R:R:F272	R:R:S13	3.96	Yes	No	0	4	5
605	R:R:L15	R:R:P273	3.28	No	No	0	5	3
606	R:R:D16	R:R:S17	4.42	No	No	0	5	4
607	R:R:D16	R:R:Y77	3.45	No	Yes	0	5	5
608	R:R:D16	R:R:D81	6.65	No	Yes	0	5	4
609	R:R:L19	R:R:P20	4.93	No	No	0	5	5
610	R:R:P20	R:R:P21	5.84	No	No	0	5	6
611	R:R:L78	R:R:P21	9.85	No	No	0	5	6
612	R:R:A280	R:R:L23	4.73	No	No	0	4	4
613	R:R:L70	R:R:Y24	7.03	Yes	Yes	3	8	8
614	R:R:T74	R:R:Y24	6.24	No	Yes	0	7	8
615	R:R:L279	R:R:Y24	3.52	No	Yes	0	6	8
616	R:R:T283	R:R:Y24	4.99	Yes	Yes	3	7	8
617	R:R:L26	R:R:L30	8.3	No	No	0	4	5
618	R:R:I67	R:R:V27	4.61	Yes	No	0	5	7
619	R:R:L287	R:R:V27	4.47	No	No	0	6	7
620	R:R:L30	R:R:T29	5.9	No	No	0	5	4
621	R:R:L32	R:R:P33	4.93	Yes	No	0	5	4
622	R:R:A34	R:R:P290	3.74	No	No	0	7	9
623	R:R:D63	R:R:N35	9.42	Yes	No	0	9	9
624	R:R:I67	R:R:N35	4.25	Yes	No	0	5	9
625	R:R:N35	R:R:P290	6.52	No	No	0	9	9
626	R:R:L37	R:R:W40	4.56	No	No	0	5	3
627	R:R:A38	R:R:S60	3.42	No	No	0	9	9
628	R:R:L39	R:R:L57	4.15	No	No	0	7	5
629	R:R:V46	R:R:W43	4.9	No	No	0	5	3
630	R:R:R47	R:R:W43	19.99	No	No	0	6	3
631	R:R:L52	R:R:Q45	3.99	Yes	No	0	7	5
632	R:R:G53	R:R:Q45	4.93	No	No	0	7	5
633	R:R:K48	R:R:R50	3.71	No	No	0	5	7
634	R:R:E51	R:R:Y55	4.49	Yes	Yes	2	6	7
635	R:R:D114	R:R:E51	14.29	Yes	Yes	2	8	6
636	R:R:E51	R:R:P126	6.29	Yes	Yes	2	6	5
637	R:R:E51	R:R:P130	4.72	Yes	No	2	6	5
638	R:R:L52	R:R:L56	4.15	Yes	No	0	7	8
639	R:R:L52	R:R:V111	4.47	Yes	No	2	7	8
640	R:R:D114	R:R:L52	4.07	Yes	Yes	2	8	7
641	R:R:L52	R:R:R115	3.64	Yes	Yes	2	7	9
642	R:R:V54	R:R:Y55	3.79	No	Yes	0	6	7
643	R:R:C110	R:R:Y55	6.72	No	Yes	0	6	7
644	R:R:D114	R:R:Y55	4.6	Yes	Yes	2	8	7
645	R:R:A134	R:R:Y55	5.34	No	Yes	0	8	7
646	R:R:V137	R:R:Y55	3.79	No	Yes	0	5	7
647	R:R:L56	R:R:Y293	3.52	No	Yes	0	8	9
648	R:R:L57	R:R:N58	4.12	No	Yes	0	5	9
649	R:R:F107	R:R:N58	13.29	No	Yes	11	7	9
650	R:R:N58	R:R:S138	5.96	Yes	No	11	9	7
651	R:R:N58	R:R:W142	4.52	Yes	Yes	11	9	9
652	R:R:L108	R:R:L59	4.15	Yes	No	2	8	9
653	R:R:D289	R:R:L59	12.21	Yes	No	2	9	9
654	R:R:N100	R:R:S62	10.43	No	Yes	0	9	8
655	R:R:S62	R:R:V103	6.46	Yes	No	11	8	7
656	R:R:S62	R:R:W142	3.71	Yes	Yes	11	8	9
657	R:R:D63	R:R:N100	4.04	Yes	No	0	9	9
658	R:R:C286	R:R:D63	9.34	No	Yes	0	7	9
659	R:R:D289	R:R:D63	6.65	Yes	Yes	0	9	9
660	R:R:L65	R:R:V96	4.47	No	No	0	7	5
661	R:R:L66	R:R:L70	4.15	Yes	Yes	3	7	8
662	R:R:F97	R:R:L66	9.74	Yes	Yes	3	7	7
663	R:R:L66	R:R:N100	16.48	Yes	No	0	7	9
664	R:R:L66	R:R:T283	4.42	Yes	Yes	3	7	7
665	R:R:I67	R:R:L70	4.28	Yes	Yes	0	5	8
666	R:R:C286	R:R:I67	4.91	No	Yes	0	7	5
667	R:R:A69	R:R:V96	3.39	No	No	0	6	5
668	R:R:F97	R:R:L70	4.87	Yes	Yes	3	7	8
669	R:R:L70	R:R:T283	5.9	Yes	Yes	3	8	7
670	R:R:P71	R:R:P72	7.79	No	No	0	9	6
671	R:R:P71	R:R:T74	3.5	No	No	0	9	7
672	R:R:F93	R:R:P72	14.45	No	No	0	5	6
673	R:R:W73	R:R:Y76	6.75	Yes	Yes	3	6	6
674	R:R:W73	R:R:Y77	3.86	Yes	Yes	3	6	5
675	R:R:G94	R:R:W73	4.22	No	Yes	0	6	6
676	R:R:F97	R:R:W73	4.01	Yes	Yes	3	7	6
677	R:R:D75	R:R:R79	11.91	No	No	0	4	4
678	R:R:D75	R:R:Y85	16.09	No	No	0	4	6
679	R:R:Y76	R:R:Y77	12.91	Yes	Yes	3	6	5
680	R:R:D81	R:R:Y76	5.75	Yes	Yes	3	4	6
681	R:R:W83	R:R:Y76	9.65	Yes	Yes	3	8	6
682	R:R:F167	R:R:Y76	5.16	Yes	Yes	3	3	6
683	R:R:E170	R:R:Y76	3.37	Yes	Yes	3	6	6
684	R:R:E170	R:R:Y77	3.37	Yes	Yes	3	6	5
685	R:R:H276	R:R:Y77	19.6	Yes	Yes	3	5	5
686	R:R:R79	R:R:V82	7.85	No	No	0	4	4
687	R:R:D81	R:R:H165	3.78	Yes	Yes	3	4	3
688	R:R:D81	R:R:F167	9.55	Yes	Yes	3	4	3
689	R:R:W83	R:R:Y85	13.5	Yes	No	0	8	6
690	R:R:C90	R:R:W83	13.06	No	Yes	3	9	8
691	R:R:F93	R:R:W83	5.01	No	Yes	0	5	8
692	R:R:C168	R:R:W83	3.92	No	Yes	3	9	8
693	R:R:G86	R:R:P87	4.06	No	No	0	8	3
694	R:R:I158	R:R:P87	6.77	No	No	0	4	3
695	R:R:C168	R:R:C90	7.28	No	No	3	9	9
696	R:R:L92	R:R:R91	6.07	No	No	0	5	7
697	R:R:L153	R:R:R91	10.93	No	No	0	4	7
698	R:R:G94	R:R:Y169	5.79	No	No	0	6	3
699	R:R:F95	R:R:T99	7.78	No	No	0	5	4
700	R:R:F95	R:R:L153	8.53	No	No	0	5	4
701	R:R:F97	R:R:Y98	11.35	Yes	No	0	7	5
702	R:R:F97	R:R:L279	7.31	Yes	No	0	7	6
703	R:R:F97	R:R:T283	3.89	Yes	Yes	3	7	7
704	R:R:E170	R:R:Y98	3.37	Yes	No	0	6	5
705	R:R:Y241	R:R:Y98	3.97	Yes	No	0	7	5
706	R:R:N149	R:R:T99	8.77	No	No	0	6	4
707	R:R:L101	R:R:Y238	7.03	No	Yes	0	7	8
708	R:R:R186	R:R:Y102	14.4	No	No	0	6	7
709	R:R:H242	R:R:Y102	6.53	Yes	No	0	8	7
710	R:R:V103	R:R:W142	14.71	No	Yes	11	7	9
711	R:R:F107	R:R:S138	6.61	No	No	11	7	7
712	R:R:F107	R:R:W142	7.02	No	Yes	11	7	9
713	R:R:L108	R:R:M198	5.65	Yes	Yes	2	8	7
714	R:R:D289	R:R:L108	8.14	Yes	Yes	2	9	8
715	R:R:L108	R:R:Y293	7.03	Yes	Yes	2	8	9
716	R:R:P194	R:R:S109	3.56	Yes	No	0	9	7
717	R:R:S109	R:R:V197	3.23	No	No	0	7	6
718	R:R:R115	R:R:V111	6.54	Yes	No	2	9	8
719	R:R:M198	R:R:S112	6.13	Yes	No	2	7	9
720	R:R:C201	R:R:S112	5.16	No	No	0	7	9
721	R:R:S112	R:R:Y202	16.53	No	Yes	2	9	9
722	R:R:D114	R:R:F125	4.78	Yes	No	0	8	5
723	R:R:R115	R:R:Y202	8.23	Yes	Yes	2	9	9
724	R:R:A120	R:R:Y116	5.34	No	No	0	7	8
725	R:R:C201	R:R:Y116	5.38	No	No	0	7	8
726	R:R:F125	R:R:L117	15.83	No	No	0	5	6
727	R:R:L205	R:R:V119	7.45	No	No	0	8	8
728	R:R:F125	R:R:P126	11.56	No	Yes	0	5	5
729	R:R:P126	R:R:P130	7.79	Yes	No	2	5	5
730	R:R:R129	R:R:R132	12.79	No	No	0	7	4
731	R:R:R132	R:R:S133	5.27	No	No	0	4	1
732	R:R:N149	R:R:R186	4.82	No	No	0	6	6
733	R:R:P151	R:R:P152	5.84	No	No	0	8	4
734	R:R:A157	R:R:Y169	4	No	No	0	4	3
735	R:R:C168	R:R:I158	3.27	No	No	0	9	4
736	R:R:H159	R:R:S171	11.16	No	No	0	1	4
737	R:R:D161	R:R:H165	12.61	No	Yes	3	1	3
738	R:R:D161	R:R:F167	3.58	No	Yes	3	1	3
739	R:R:F167	R:R:H165	10.18	Yes	Yes	3	3	3
740	R:R:F167	R:R:Y172	5.16	Yes	Yes	3	3	5
741	R:R:E170	R:R:Y172	6.73	Yes	Yes	3	6	5
742	R:R:E170	R:R:H276	9.85	Yes	Yes	3	6	5
743	R:R:R248	R:R:Y172	5.14	Yes	Yes	3	5	5
744	R:R:E268	R:R:Y172	12.35	No	Yes	3	4	5
745	R:R:F272	R:R:Y172	6.19	Yes	Yes	3	4	5
746	R:R:Y172	R:R:Y275	3.97	Yes	Yes	3	5	6
747	R:R:H276	R:R:Y172	5.44	Yes	Yes	3	5	5
748	R:R:L174	R:R:R248	3.64	No	Yes	0	3	5
749	R:R:F252	R:R:L174	4.87	No	No	0	4	3
750	R:R:L253	R:R:R177	7.29	No	No	0	4	1
751	R:R:L181	R:R:L253	5.54	No	No	0	3	4
752	R:R:L245	R:R:N183	10.98	No	No	0	6	5
753	R:R:N183	R:R:S249	5.96	No	No	0	5	5
754	R:R:S249	R:R:V184	3.23	No	No	0	5	4
755	R:R:H242	R:R:V187	4.15	Yes	No	0	8	6
756	R:R:L245	R:R:V187	4.47	No	No	0	6	6
757	R:R:L246	R:R:V187	5.96	No	No	0	6	6
758	R:R:G190	R:R:P194	4.06	No	Yes	0	6	9
759	R:R:F191	R:R:L192	10.96	Yes	No	0	9	4
760	R:R:F191	R:R:W195	7.02	Yes	Yes	0	9	6
761	R:R:F191	R:R:Y238	4.13	Yes	Yes	18	9	8
762	R:R:F191	R:R:H242	12.44	Yes	Yes	18	9	8
763	R:R:L193	R:R:P194	4.93	No	Yes	0	5	9
764	R:R:M199	R:R:W195	3.49	No	Yes	0	4	6
765	R:R:L235	R:R:W195	13.67	No	Yes	0	5	6
766	R:R:M198	R:R:Y202	4.79	Yes	Yes	2	7	9
767	R:R:M198	R:R:P231	8.39	Yes	Yes	2	7	7
768	R:R:A234	R:R:M198	3.22	No	Yes	0	9	7
769	R:R:L228	R:R:M199	4.24	No	No	0	4	4
770	R:R:M199	R:R:P231	5.03	No	Yes	0	4	7
771	R:R:A227	R:R:Y202	4	No	Yes	0	7	9
772	R:R:L230	R:R:Y202	5.86	Yes	Yes	2	7	9
773	R:R:P231	R:R:Y202	9.74	Yes	Yes	2	7	9
774	R:R:A227	R:R:L206	6.3	No	No	0	7	5
775	R:R:L209	R:R:R220	4.86	No	No	0	8	6
776	R:R:C215	R:R:S212	3.44	No	No	0	2	5
777	R:R:R220	R:R:S212	3.95	No	No	0	6	5
778	R:R:E216	R:R:R218	5.82	No	No	0	5	3
779	R:R:E216	R:R:E219	7.61	No	No	0	5	5
780	R:R:C232	R:R:G229	3.92	No	No	0	4	5
781	R:R:L230	R:R:P231	3.28	Yes	Yes	2	7	7
782	R:R:L230	R:R:L292	4.15	Yes	No	0	7	7
783	R:R:L230	R:R:Y293	10.55	Yes	Yes	2	7	9
784	R:R:L292	R:R:V233	4.47	No	No	0	7	6
785	R:R:C237	R:R:N285	7.87	No	No	0	8	9
786	R:R:H242	R:R:Y238	3.27	Yes	Yes	18	8	8
787	R:R:N285	R:R:Y238	9.3	No	Yes	0	9	8
788	R:R:G239	R:R:P240	4.06	No	No	0	6	9
789	R:R:L281	R:R:P240	3.28	No	No	0	7	9
790	R:R:H242	R:R:Y241	6.53	Yes	Yes	0	8	7
791	R:R:Y241	R:R:Y275	16.88	Yes	Yes	0	7	6
792	R:R:S278	R:R:Y241	5.09	No	Yes	0	7	7
793	R:R:L279	R:R:Y241	9.38	No	Yes	0	6	7
794	R:R:L245	R:R:Y275	8.21	No	Yes	0	6	6
795	R:R:L271	R:R:R248	4.86	No	Yes	0	4	5
796	R:R:R248	R:R:Y275	5.14	Yes	Yes	3	5	6
797	R:R:L267	R:R:V251	4.47	No	No	0	1	4
798	R:R:L267	R:R:L271	4.15	No	No	0	1	4
799	R:R:E268	R:R:F272	4.66	No	Yes	3	4	4
800	R:R:F272	R:R:P273	4.33	Yes	No	0	4	3
801	R:R:F272	R:R:H276	13.58	Yes	Yes	3	4	5
802	R:R:H276	R:R:Y275	4.36	Yes	Yes	3	5	6
803	R:R:D289	R:R:N285	13.46	Yes	No	0	9	9
804	R:R:D289	R:R:Y293	4.6	Yes	Yes	2	9	9
805	R:R:A300	R:R:C294	3.61	No	No	0	8	6
806	R:R:L295	R:R:R301	7.29	No	No	0	8	8
807	B:B:V320	B:B:V327	3.21	No	No	0	7	6
808	R:R:V46	R:R:V54	3.21	No	No	0	5	6
809	A:A:S349	A:A:T350	3.2	Yes	No	0	7	4
810	B:B:S265	B:B:T249	3.2	No	No	0	2	6
811	B:B:S265	B:B:T263	3.2	No	No	0	2	1
812	R:R:C68	R:R:L64	3.17	No	No	0	4	7
813	B:B:A242	B:B:L285	3.15	No	Yes	0	4	6
814	R:R:A180	R:R:L253	3.15	No	No	0	3	4
815	A:A:T204	B:B:T143	3.14	No	No	0	9	5
816	A:A:E327	A:A:P328	3.14	No	No	0	4	1
817	B:B:T177	B:B:T178	3.14	No	No	0	4	4
818	A:A:A48	A:A:N50	3.13	No	Yes	0	8	9
819	A:A:I276	A:A:S275	3.1	No	No	0	8	8
820	B:B:A193	B:B:D195	3.09	No	No	0	4	5
821	B:B:D254	G:G:A33	3.09	No	No	0	9	7
822	R:R:I141	R:R:V137	3.07	No	No	0	6	5
823	A:A:K300	A:A:S306	3.06	No	No	0	9	7
824	A:A:M221	A:A:V57	3.04	No	No	0	8	7
825	A:A:E392	R:R:A300	3.02	No	No	0	6	8
826	B:B:T34	G:G:M38	3.01	No	No	0	5	4
827	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
828	R:R:F252	R:R:G176	3.01	No	No	0	4	1
829	R:R:F191	R:R:G239	3.01	Yes	No	0	9	6
830	A:A:L297	A:A:S251	3	Yes	No	0	8	9
831	R:R:L244	R:R:S278	3	No	No	0	5	7
832	A:A:V217	R:R:L123	2.98	No	Yes	0	5	5
833	A:A:N278	A:A:S352	2.98	No	No	0	8	5
834	A:A:L297	A:A:V301	2.98	Yes	No	0	8	7
835	B:B:L168	B:B:V213	2.98	No	No	0	6	4
836	G:G:N59	G:G:V54	2.96	No	No	0	9	6
837	A:A:L12	A:A:T11	2.95	Yes	No	0	2	4
838	B:B:L168	B:B:T178	2.95	No	No	0	6	4
839	B:B:L318	B:B:T329	2.95	No	Yes	0	6	8
840	G:G:L51	G:G:T52	2.95	Yes	No	0	6	4
841	R:R:A120	R:R:H121	2.93	No	No	0	7	6
842	A:A:N218	A:A:T40	2.92	No	No	0	4	7
843	A:A:I62	A:A:K58	2.91	No	No	0	9	9
844	R:R:G190	R:R:Y102	2.9	No	No	0	6	7
845	R:R:G204	R:R:Y116	2.9	No	No	0	4	8
846	B:B:D322	B:B:T65	2.89	No	No	0	1	1
847	B:B:F151	B:B:P107	2.89	Yes	No	0	9	6
848	B:B:D170	B:B:T177	2.89	No	No	0	9	4
849	A:A:I26	A:A:L30	2.85	No	No	0	9	5
850	B:B:I18	G:G:L19	2.85	Yes	No	0	7	9
851	G:G:E58	G:G:V54	2.85	No	No	0	5	6
852	R:R:E145	R:R:V103	2.85	No	No	0	7	7
853	A:A:K17	A:A:L12	2.82	No	Yes	0	3	2
854	A:A:L30	B:B:K78	2.82	No	No	0	5	8
855	A:A:G353	A:A:W277	2.81	No	Yes	0	4	6
856	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
857	R:R:G196	R:R:W195	2.81	No	Yes	0	2	6
858	G:G:K20	G:G:N24	2.8	No	No	0	6	1
859	R:R:P20	R:R:Y24	2.78	No	Yes	0	5	8
860	R:R:P152	R:R:Y169	2.78	No	No	0	4	3
861	A:A:D310	A:A:K307	2.77	No	No	0	3	6
862	A:A:L393	R:R:L226	2.77	Yes	No	0	8	7
863	B:B:L14	G:G:L19	2.77	No	No	0	8	9
864	B:B:A113	B:B:F151	2.77	No	Yes	0	9	9
865	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
866	B:B:A240	B:B:F235	2.77	No	Yes	0	6	6
867	R:R:L19	R:R:L23	2.77	No	No	0	5	4
868	R:R:L26	R:R:L287	2.77	No	No	0	4	6
869	R:R:L32	R:R:L36	2.77	Yes	No	0	5	3
870	R:R:L36	R:R:L64	2.77	No	No	0	3	7
871	R:R:L61	R:R:L65	2.77	No	No	0	6	7
872	R:R:A180	R:R:F252	2.77	No	No	0	3	4
873	R:R:L284	R:R:L287	2.77	No	No	0	5	6
874	B:B:I18	B:B:Q17	2.74	Yes	No	0	7	4
875	B:B:E138	B:B:I120	2.73	No	No	0	6	6
876	A:A:K32	A:A:Q29	2.71	No	No	0	4	4
877	A:A:K34	A:A:Q31	2.71	No	No	0	4	4
878	A:A:E330	A:A:K338	2.7	Yes	Yes	0	3	5
879	A:A:Y358	R:R:A213	2.67	No	No	0	4	3
880	B:B:Q13	B:B:Q9	2.56	No	No	0	1	3
881	B:B:S136	B:B:Y111	2.54	No	Yes	0	4	4
882	R:R:E268	R:R:E269	2.54	No	No	0	4	2
883	A:A:T325	A:A:Y339	2.5	No	Yes	0	2	3
884	A:A:T335	A:A:Y339	2.5	No	Yes	0	4	3
885	R:R:F28	R:R:L32	2.44	No	Yes	0	7	5
886	R:R:F95	R:R:L146	2.44	No	No	0	5	3
887	A:A:L394	R:R:R222	2.43	Yes	No	0	8	8
888	B:B:L139	B:B:R137	2.43	Yes	No	0	9	5
889	R:R:L206	R:R:R224	2.43	No	No	0	5	5
890	R:R:H165	R:R:Y163	2.18	Yes	No	0	3	2
891	R:R:R218	R:R:R221	2.13	No	No	0	3	5
892	B:B:G115	B:B:G116	2.11	No	No	0	9	9
893	R:R:G263	R:R:G264	2.11	No	No	0	2	3
894	R:R:R162	R:R:Y163	2.06	No	No	0	2	2
895	R:R:G127	R:R:P126	2.03	No	Yes	0	4	5
896	R:R:G299	R:R:P298	2.03	No	No	0	6	6
897	B:B:C114	B:B:G115	1.96	Yes	No	0	8	9
898	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
899	B:B:C271	B:B:G272	1.96	Yes	No	0	5	4
900	B:B:C317	B:B:G330	1.96	No	No	0	7	5
901	A:A:A226	A:A:G206	1.95	No	No	0	9	8
902	A:A:A303	A:A:G304	1.95	No	No	0	5	5
903	R:R:A34	R:R:G31	1.95	No	No	0	7	8
904	R:R:C297	R:R:P298	1.88	No	No	0	7	6
905	R:R:A38	R:R:P290	1.87	No	No	0	9	9
906	R:R:A105	R:R:P194	1.87	No	Yes	0	8	9
907	R:R:A150	R:R:P151	1.87	No	No	0	3	8
908	B:B:G77	B:B:S98	1.86	No	No	0	8	8
909	R:R:G14	R:R:S13	1.86	No	No	0	2	5
910	R:R:G104	R:R:S62	1.86	No	Yes	0	9	8
911	B:B:G41	B:B:V40	1.84	No	No	0	1	3
912	B:B:G306	B:B:V296	1.84	No	No	0	4	5
913	B:B:G306	B:B:V307	1.84	No	No	0	4	3
914	B:B:G244	B:B:T243	1.82	No	Yes	0	5	8
915	B:B:A104	B:B:C149	1.81	No	No	0	7	8
916	R:R:A41	R:R:C294	1.81	No	No	0	7	6
917	R:R:A113	R:R:C201	1.81	No	No	0	5	7
918	R:R:A120	R:R:A208	1.79	No	No	0	7	5
919	R:R:A155	R:R:A157	1.79	No	No	0	3	4
920	B:B:P107	B:B:T65	1.75	No	No	0	6	1
921	G:G:P53	G:G:T52	1.75	No	No	0	8	4
922	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
923	B:B:G182	B:B:K209	1.74	No	Yes	0	6	6
924	B:B:G310	B:B:K337	1.74	No	Yes	0	5	6
925	B:B:A28	G:G:S31	1.71	No	No	0	4	9
926	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
927	A:A:A269	A:A:V248	1.7	No	No	0	9	7
928	A:A:A298	A:A:V334	1.7	No	No	0	4	4
929	A:A:A337	A:A:V301	1.7	No	No	0	8	7
930	B:B:A11	G:G:V16	1.7	No	No	0	5	7
931	B:B:A26	G:G:V30	1.7	No	No	0	3	8
932	R:R:A288	R:R:V233	1.7	No	No	0	6	6
933	A:A:E330	A:A:G329	1.64	Yes	No	0	3	7
934	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
935	B:B:E215	B:B:G216	1.64	No	No	0	3	4
936	B:B:E260	B:B:G224	1.64	No	No	0	6	6
937	A:A:I26	B:B:A92	1.62	No	No	0	9	6
938	B:B:I33	G:G:A34	1.62	No	No	0	3	6
939	B:B:I33	G:G:A35	1.62	No	No	0	3	2
940	B:B:A140	B:B:I120	1.62	No	No	0	5	6
941	B:B:A248	B:B:I269	1.62	No	No	0	5	4
942	R:R:S17	R:R:V18	1.62	No	No	0	4	4
943	R:R:S22	R:R:V18	1.62	No	No	0	3	4
944	R:R:A106	R:R:I141	1.62	No	No	0	6	6
945	R:R:A135	R:R:I131	1.62	No	No	0	4	3
946	B:B:S31	B:B:T29	1.6	No	No	0	1	3
947	B:B:S207	B:B:T223	1.6	No	No	0	5	2
948	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
949	R:R:A277	R:R:L19	1.58	No	No	0	5	5
950	R:R:A42	R:R:L56	1.58	No	No	0	6	8
951	R:R:A42	R:R:L57	1.58	No	No	0	6	5
952	R:R:A282	R:R:L101	1.58	No	No	0	8	7
953	R:R:A274	R:R:L244	1.58	No	No	0	4	5
954	R:R:A274	R:R:L271	1.58	No	No	0	4	4
955	R:R:A291	R:R:L292	1.58	No	No	0	6	7
956	A:A:E322	A:A:P321	1.57	No	No	0	1	5
957	A:A:A19	B:B:N88	1.56	No	Yes	0	4	7
958	G:G:A23	G:G:N24	1.56	No	No	0	8	1
959	G:G:A56	G:G:N59	1.56	No	No	0	4	9
960	R:R:A148	R:R:N149	1.56	No	No	0	4	6
961	R:R:I131	R:R:V54	1.54	No	No	0	3	6
962	B:B:M262	B:B:S31	1.53	Yes	No	0	4	1
963	B:B:A28	B:B:Q32	1.52	No	No	0	4	1
964	R:R:I158	R:R:T166	1.52	No	No	0	4	5
965	R:R:G204	R:R:R207	1.5	No	No	0	4	4
966	A:A:L12	A:A:V20	1.49	Yes	No	0	2	3
967	R:R:L188	R:R:V184	1.49	No	No	0	4	4
968	R:R:L247	R:R:V251	1.49	No	No	0	5	4
969	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
970	G:G:A43	G:G:H44	1.46	No	No	0	4	6
971	A:A:F312	A:A:P313	1.44	No	No	0	8	6
972	R:R:I67	R:R:L32	1.43	Yes	Yes	0	5	5
973	A:A:E370	A:A:T369	1.41	No	No	0	4	9
974	B:B:K15	G:G:L19	1.41	No	No	0	6	9
975	B:B:K301	B:B:N35	1.4	Yes	No	0	5	1
976	B:B:C25	G:G:R27	1.39	No	Yes	0	3	8
977	R:R:A89	R:R:F93	1.39	No	No	0	5	5
978	G:G:A56	G:G:R62	1.38	No	No	0	4	7
979	R:R:L153	R:R:L154	1.38	No	No	0	4	4
980	A:A:A254	A:A:Y311	1.33	No	No	0	9	6
981	A:A:F208	A:A:S205	1.32	No	No	0	5	7
982	R:R:R80	R:R:S17	1.32	No	No	0	3	4
983	A:A:R333	A:A:V301	1.31	No	No	0	5	7
984	B:B:D5	B:B:Q6	1.31	No	No	0	1	1
985	B:B:D5	B:B:Q9	1.31	No	No	0	1	3
986	B:B:E172	B:B:N155	1.31	No	No	0	6	3
987	A:A:D323	A:A:E322	1.3	No	No	0	4	1
988	A:A:R356	A:A:T284	1.29	No	No	0	2	4
989	R:R:R160	R:R:T166	1.29	No	No	0	1	5
990	B:B:E12	B:B:Q13	1.27	No	No	0	4	1
991	B:B:D267	B:B:H266	1.26	No	No	0	3	4
992	B:B:K23	B:B:R19	1.24	No	No	0	2	4
993	A:A:L302	A:A:R333	1.21	No	No	0	2	5
994	R:R:L37	R:R:R301	1.21	No	No	0	5	8
995	R:R:L44	R:R:R47	1.21	No	No	0	4	6
996	A:A:D354	A:A:R356	1.19	No	No	0	3	2
997	B:B:D212	B:B:R214	1.19	No	No	0	9	9
998	A:A:Q35	R:R:R129	1.17	No	No	0	3	7
999	R:R:Q217	R:R:R221	1.17	No	No	0	3	5
1000	R:R:L36	R:R:W40	1.14	No	No	0	3	3
1001	R:R:L39	R:R:W40	1.14	No	No	0	7	3
1002	A:A:H357	A:A:R356	1.13	No	No	0	7	2
1003	R:R:R210	R:R:R220	1.07	No	No	0	5	6
1004	R:R:R224	R:R:R225	1.07	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:L12	3.1725	4	0	2
2	A:A:H41	7.3375	4	2	6
3	A:A:N50	7.346	5	13	9
4	A:A:F219	7.3	4	0	8
5	A:A:H220	12.2775	4	1	7
6	A:A:F222	9.8925	4	1	7
7	A:A:E230	10.3325	4	1	9
8	A:A:K233	5.71	7	1	9
9	A:A:W234	7.95	6	1	9
10	A:A:F238	10.0825	4	0	9
11	A:A:V247	5.0125	4	10	7
12	A:A:Y253	7.53	4	0	8
13	A:A:R265	9.225	4	13	9
14	A:A:F273	5.5	4	0	9
15	A:A:W277	8.724	5	0	6
16	A:A:W281	7.164	5	1	5
17	A:A:F290	6.14	5	10	9
18	A:A:N292	4.92	5	10	9
19	A:A:K293	7.4775	4	0	9
20	A:A:Q294	7.7075	4	9	6
21	A:A:L297	4.666	5	9	8
22	A:A:E330	4.0475	4	0	3
23	A:A:K338	7.6275	4	9	5
24	A:A:Y339	5.31667	6	9	3
25	A:A:F340	9.695	4	0	7
26	A:A:R342	6.49	5	9	4
27	A:A:S349	5.26	4	0	7
28	A:A:Y360	9.6475	4	0	8
29	A:A:F363	9.264	5	9	5
30	A:A:T364	6.1225	4	10	9
31	A:A:N371	4.5225	4	10	9
32	A:A:R373	6.26	4	14	5
33	A:A:R374	7.885	4	10	4
34	A:A:F376	5.258	5	14	8
35	A:A:I383	4.64	4	2	8
36	A:A:Y391	5.71833	6	2	4
37	A:A:L393	4.37	4	0	8
38	A:A:L394	4.45	4	0	8
39	B:B:I18	3.4625	4	0	7
40	B:B:H54	10.5525	4	0	9
41	B:B:K57	8.582	5	1	9
42	B:B:Y59	10.262	5	1	8
43	B:B:W63	6.01714	7	6	7
44	B:B:L79	5.5175	4	8	7
45	B:B:W82	10.682	5	0	9
46	B:B:N88	6.29	4	0	7
47	B:B:K89	7.026	5	0	9
48	B:B:H91	5.2575	4	8	5
49	B:B:I93	6.1725	4	8	7
50	B:B:L95	5.555	4	8	8
51	B:B:W99	9.88667	6	1	9
52	B:B:Y105	4.144	5	0	6
53	B:B:N110	6.9025	4	15	4
54	B:B:Y111	6.098	5	15	4
55	B:B:C114	4.692	5	8	8
56	B:B:Y124	4.82714	7	8	6
57	B:B:L139	6.21	4	0	9
58	B:B:H142	8.4025	4	1	9
59	B:B:Y145	6.51375	8	1	8
60	B:B:F151	6.6025	4	0	9
61	B:B:L152	5.615	4	0	3
62	B:B:T159	7.8675	4	1	9
63	B:B:D163	6.54	5	1	9
64	B:B:W169	9.962	5	1	8
65	B:B:Q176	7.61	4	1	4
66	B:B:F180	9.765	4	4	7
67	B:B:H183	9.708	5	4	9
68	B:B:D186	9.445	4	1	9
69	B:B:V187	5.715	4	4	9
70	B:B:F199	8.116	5	4	9
71	B:B:V200	6.915	4	5	6
72	B:B:S201	4.915	4	4	9
73	B:B:C204	4.0675	4	1	7
74	B:B:K209	8.85	5	4	6
75	B:B:W211	9.964	5	4	8
76	B:B:C218	5.5875	4	4	5
77	B:B:F222	8.815	4	5	8
78	B:B:H225	10.3383	6	5	9
79	B:B:D228	7.824	5	1	9
80	B:B:F234	5.755	4	0	5
81	B:B:F235	7.33143	7	12	6
82	B:B:F241	8.062	5	5	6
83	B:B:T243	5.5925	4	5	8
84	B:B:D247	8.6125	4	5	9
85	B:B:R251	12.8975	4	0	8
86	B:B:F253	9.59	4	5	6
87	B:B:R256	8.1825	4	0	9
88	B:B:D258	9.8725	4	5	7
89	B:B:M262	4.0425	4	0	4
90	B:B:Y264	5.702	5	0	5
91	B:B:C271	4.61	4	1	5
92	B:B:I273	4.925	4	0	6
93	B:B:F278	7.6675	4	12	7
94	B:B:R283	8.765	4	0	9
95	B:B:L285	4.79	4	0	6
96	B:B:Y289	5.95167	6	1	7
97	B:B:D290	7.0875	4	1	6
98	B:B:N295	8.47	4	1	6
99	B:B:K301	5.158	5	16	5
100	B:B:H311	9.408	5	7	9
101	B:B:R314	14.065	4	1	8
102	B:B:V315	4.4275	4	7	7
103	B:B:T329	4.896	5	7	8
104	B:B:W332	10.5829	7	1	9
105	B:B:D333	8.13	4	7	9
106	B:B:K337	6.772	5	7	6
107	B:B:I338	4.9375	4	6	5
108	B:B:W339	8.348	5	7	9
109	G:G:R27	5.3975	4	0	8
110	G:G:Y40	9.9825	4	12	6
111	G:G:D48	7.625	4	0	9
112	G:G:L51	5.3275	4	0	6
113	G:G:F61	5.99571	7	6	8
114	R:R:Y24	4.912	5	3	8
115	R:R:L32	2.8925	4	0	5
116	R:R:E51	6.856	5	2	6
117	R:R:L52	4.16833	6	2	7
118	R:R:Y55	4.78833	6	2	7
119	R:R:N58	6.9725	4	11	9
120	R:R:S62	5.615	4	11	8
121	R:R:D63	7.3625	4	0	9
122	R:R:L66	8.6975	4	3	7
123	R:R:I67	3.896	5	0	5
124	R:R:L70	5.246	5	3	8
125	R:R:W73	4.71	4	3	6
126	R:R:Y76	7.265	6	3	6
127	R:R:Y77	8.638	5	3	5
128	R:R:D81	6.4325	4	3	4
129	R:R:W83	9.028	5	3	8
130	R:R:F97	6.86167	6	3	7
131	R:R:L108	6.2425	4	2	8
132	R:R:D114	7.158	5	2	8
133	R:R:R115	5.5125	4	2	9
134	R:R:L123	5.1225	4	0	5
135	R:R:P126	6.9175	4	2	5
136	R:R:W142	7.49	4	11	9
137	R:R:H165	6.866	5	3	3
138	R:R:F167	6.726	5	3	3
139	R:R:E170	5.338	5	3	6
140	R:R:Y172	6.42571	7	3	5
141	R:R:F191	7.512	5	18	9
142	R:R:P194	3.605	4	0	9
143	R:R:W195	6.7475	4	0	6
144	R:R:M198	5.636	5	2	7
145	R:R:Y202	8.19167	6	2	9
146	R:R:L230	5.96	4	2	7
147	R:R:P231	6.61	4	2	7
148	R:R:Y238	5.9325	4	18	8
149	R:R:Y241	8.37	5	0	7
150	R:R:H242	6.584	5	18	8
151	R:R:R248	4.695	4	3	5
152	R:R:F272	6.544	5	3	4
153	R:R:Y275	7.712	5	3	6
154	R:R:H276	10.566	5	3	5
155	R:R:T283	4.8	4	3	7
156	R:R:D289	9.012	5	2	9
157	R:R:Y293	6.425	4	2	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:D66	B:B:R68	19.1815	3.57	No	No	0	8	5
2	B:B:D66	B:B:L69	19.0114	6.79	No	No	0	8	5
3	B:B:L69	B:B:Y105	18.8413	3.52	No	Yes	0	5	6
4	B:B:R68	B:B:Y85	20.9447	27.78	No	No	0	5	4
5	B:B:Y85	G:G:P60	23.1481	16.69	No	No	0	4	9
6	B:B:M325	G:G:P60	23.3077	3.35	No	No	0	5	9
7	B:B:M325	G:G:P49	33.6713	6.71	No	No	0	5	7
8	G:G:D48	G:G:P49	34.1496	3.22	Yes	No	0	9	7
9	G:G:D48	G:G:L51	39.9903	8.14	Yes	Yes	0	9	6
10	B:B:L284	G:G:L51	41.2082	4.15	No	Yes	0	5	6
11	B:B:L284	B:B:V296	42.8943	5.96	No	No	0	5	5
12	B:B:G306	B:B:V296	43.044	1.84	No	No	0	4	5
13	B:B:G306	B:B:V307	43.1944	1.84	No	No	0	4	3
14	B:B:N295	B:B:V307	43.6474	4.43	Yes	No	0	6	3
15	B:B:N295	B:B:Y289	43.7273	10.47	Yes	Yes	1	6	7
16	B:B:C271	B:B:Y289	60.8284	4.03	Yes	Yes	1	5	7
17	B:B:C271	B:B:D290	61.2691	4.67	Yes	Yes	1	5	6
18	A:A:W281	B:B:D290	59.9141	3.35	Yes	Yes	1	5	6
19	A:A:N279	A:A:W281	59.5898	3.39	No	Yes	1	8	5
20	A:A:I235	A:A:N279	59.6425	4.25	No	No	1	9	8
21	A:A:I235	A:A:W234	60.221	3.52	No	Yes	1	9	9
22	A:A:R231	A:A:W234	74.8236	12	No	Yes	0	9	9
23	A:A:D272	A:A:R231	75.1976	3.57	No	No	0	8	9
24	A:A:D272	A:A:E268	75.3223	6.5	No	No	0	8	9
25	A:A:E268	A:A:R265	75.4469	6.98	No	Yes	0	9	9
26	A:A:N50	A:A:R265	75.53	12.05	Yes	Yes	13	9	9
27	A:A:D249	A:A:N50	76.0683	12.12	No	Yes	0	8	9
28	A:A:D249	A:A:K293	87.0305	16.59	No	Yes	0	8	9
29	A:A:K293	A:A:N292	93.6763	5.6	Yes	Yes	0	9	9
30	A:A:N292	A:A:T364	95.438	5.85	Yes	Yes	10	9	9
31	A:A:F290	A:A:T364	63.6766	9.08	Yes	Yes	10	9	9
32	A:A:W234	B:B:Y145	12.0871	5.79	Yes	Yes	1	9	8
33	A:A:F290	A:A:I288	32.0259	3.77	Yes	No	0	9	9
34	A:A:D249	A:A:S251	14.7979	5.89	No	No	0	8	9
35	A:A:L297	A:A:S251	31.1811	3	Yes	No	0	8	9
36	A:A:L297	A:A:Q294	18.7391	6.65	Yes	Yes	9	8	6
37	A:A:F363	A:A:Q294	14.2326	11.71	Yes	Yes	9	5	6
38	A:A:L296	A:A:S251	16.8927	6.01	No	No	0	6	9
39	A:A:K293	A:A:L296	13.0469	4.23	Yes	No	0	9	6
40	A:A:D378	A:A:I288	32.0592	13.99	No	No	0	7	9
41	A:A:D378	A:A:Y360	100	12.64	No	Yes	0	7	8
42	A:A:F290	A:A:H362	31.9955	6.79	Yes	No	0	9	9
43	A:A:D378	A:A:H362	67.9865	10.08	No	No	0	7	9
44	A:A:R374	A:A:T364	31.8169	5.17	Yes	Yes	10	4	9
45	A:A:H362	A:A:R374	36.0085	19.18	No	Yes	0	9	4
46	A:A:Y358	A:A:Y360	49.7489	11.91	No	Yes	0	4	8
47	A:A:Y358	R:R:S214	49.6118	3.82	No	No	0	4	3
48	A:A:D381	A:A:Y360	50.1183	9.2	No	Yes	0	8	8
49	A:A:D381	R:R:S214	49.707	4.42	No	No	0	8	3
50	A:A:R385	R:R:S214	99.157	5.27	No	No	0	5	3
51	A:A:R385	R:R:E219	98.8355	10.47	No	No	0	5	5
52	A:A:L394	R:R:E219	98.0319	3.98	Yes	No	0	8	5
53	A:A:L388	A:A:L394	97.5517	6.92	No	Yes	0	8	8
54	A:A:L388	A:A:L393	97.3918	4.15	No	Yes	0	8	8
55	A:A:L393	R:R:R115	96.746	3.64	Yes	Yes	0	8	9
56	R:R:L52	R:R:R115	27.7071	3.64	Yes	Yes	2	7	9
57	B:B:A287	B:B:Y289	10.1925	4	No	Yes	0	6	7
58	B:B:A287	B:B:I273	10.0279	3.25	No	Yes	0	6	6
59	B:B:H62	B:B:Y105	10.7554	3.27	No	Yes	0	6	6
60	B:B:H62	B:B:R150	10.5815	19.18	No	No	0	6	6
61	B:B:D323	B:B:M325	10.2372	8.32	No	No	0	7	5
62	B:B:L192	B:B:R150	10.4075	4.86	No	No	0	5	6
63	B:B:L152	B:B:L192	10.2334	6.92	Yes	No	0	3	5
64	R:R:R115	R:R:Y202	68.9062	8.23	Yes	Yes	2	9	9
65	R:R:P231	R:R:Y202	21.6859	9.74	Yes	Yes	2	7	9
66	R:R:M199	R:R:P231	21.5609	5.03	No	Yes	0	4	7
67	R:R:M199	R:R:W195	21.1887	3.49	No	Yes	0	4	6
68	R:R:F191	R:R:W195	20.65	7.02	Yes	Yes	0	9	6
69	R:R:F191	R:R:H242	19.1923	12.44	Yes	Yes	18	9	8
70	R:R:H242	R:R:Y241	14.8841	6.53	Yes	Yes	0	8	7
71	R:R:L52	R:R:L56	30.2602	4.15	Yes	No	0	7	8
72	R:R:L56	R:R:Y293	25.5847	3.52	No	Yes	0	8	9
73	R:R:D289	R:R:Y293	46.8078	4.6	Yes	Yes	2	9	9
74	R:R:D289	R:R:D63	64.625	6.65	Yes	Yes	0	9	9
75	R:R:D63	R:R:N100	34.3733	4.04	Yes	No	0	9	9
76	R:R:L66	R:R:N100	32.6859	16.48	Yes	No	0	7	9
77	R:R:F97	R:R:L66	18.1449	9.74	Yes	Yes	3	7	7
78	R:R:F97	R:R:W73	17.6142	4.01	Yes	Yes	3	7	6
79	R:R:L230	R:R:Y202	22.5498	5.86	Yes	Yes	2	7	9
80	R:R:L230	R:R:Y293	21.6817	10.55	Yes	Yes	2	7	9
81	R:R:M198	R:R:Y202	22.1643	4.79	Yes	Yes	2	7	9
82	R:R:L108	R:R:M198	21.8907	5.65	Yes	Yes	2	8	7
83	R:R:D289	R:R:L108	21.5256	8.14	Yes	Yes	2	9	8
84	R:R:D63	R:R:N35	16.3086	9.42	Yes	No	0	9	9
85	R:R:I67	R:R:N35	12.8503	4.25	Yes	No	0	5	9
86	R:R:I67	R:R:L70	14.1701	4.28	Yes	Yes	0	5	8
87	R:R:L70	R:R:Y24	19.2587	7.03	Yes	Yes	3	8	8
88	R:R:P20	R:R:Y24	17.6317	2.78	No	Yes	0	5	8
89	R:R:L19	R:R:P20	10.0757	4.93	No	No	0	5	5
90	R:R:C286	R:R:D63	13.391	9.34	No	Yes	0	7	9
91	R:R:C286	R:R:I67	12.8146	4.91	No	Yes	0	7	5
92	R:R:W83	R:R:Y76	10.8267	9.65	Yes	Yes	3	8	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8ZD1

PDB Summary
PDB	8ZD1
Class	A
SubFamily	Orphan
Type	Orphan
SubType	GPR4
Species	Xenopus tropicalis
Ligand	-
Other Ligand(s)	-
Protein Partners	chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution	2.6
Date	2025-02-26
D.O.I.	doi.org/10.1016/j.cell.2024.12.001

Net Summary
I_min	3.22
Number of Linked Nodes	839
Number of Links	1004
Number of Hubs	157
Number of Links mediated by Hubs	559
Number of Communities	18
Number of Nodes involved in Communities	199
Number of Links involved in Communities	293

Path Summary
Number Of Nodes in MetaPath	93
Number Of Links MetaPath	92
Number of Shortest Paths	3070205
Length Of Smallest Path	3
Average Path Length	39.5245
Length of Longest Path	70
Minimum Path Strength	1.14
Average Path Strength	6.96645
Maximum Path Strength	22.235
Minimum Path Correlation	0.7
Average Path Correlation	0.989157
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.43902
Average % Of Corr. Nodes	33.693
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	50.9157
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • cell-cell signaling • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • multicellular organismal process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • cell population proliferation • cellular process • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • signal transduction • cell communication • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to monoamine stimulus • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • response to pH • cellular response to pH • response to abiotic stimulus • cellular response to acidic pH • response to acidic pH • cellular response to abiotic stimulus • cellular response to environmental stimulus • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8ZD1_Chain_A I E K Q L Q K D K Q V Y R A T H R L L L L G A S G K S T I V K Q M R I H V V T S G I F E T K F Q V D K V N F H M F D V G Q R D E R R K W I Q C F N D V T A I I F V V S S Y R L Q E A L N F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C V D T E N R R F N D C R D I I Q R M H L R Q Y E L L T L S E A D K A A V E R S M D N Y K A D D A D S A I K Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8ZD1_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8ZD1_Chain_G Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	A0A6I8PUB9
Sequence	>8ZD1_Chain_R S G L D S V L P P S L Y A L V F T L G L P A N L L A L W A A W L Q V R K G R E L G V Y L L N L S L S D L L L I C A L P P W T D Y Y L R R D V W G Y G P G A C R L F G F V F Y T N L Y V G A A F L S C V S A D R Y L A V A H P L R F P G A R P I R S A A A V S A L I W M L E L A A N A P P L L E A I H R D R Y N H T F C Y E S Y P L S G R G A A L A N V G R V L A G F L L P W G V M M L C Y A G L L R A L R G S A S C E Q R E R R R V R R L A L G L P C V A L L C Y G P Y H A L L L L R S L V F L V G G C A L E E R L F P A Y H A S L A L A T L N C L A D P A L Y C L A C P G A R A Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9JCP	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs-CtGq)/β1/γ2	2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCO	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCO (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	8ZD1	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZD1 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF4	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.05	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF7	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.15	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9 (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFB	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.78	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFD	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFE	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVH	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVM	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	2.36	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9BIP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BIP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	8ZCE	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCE (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFU	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	3.23	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi2-G13)/β1/γ2	3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZFZ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31 (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8Z3M	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2025-04-23	To be published
	8Z3M (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	To be published
	8Z3Q	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-04-23	To be published
	8Z3Q (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.76	2025-04-23	To be published
	8Z65	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-04-23	To be published
	8Z65 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.98	2025-04-23	To be published
	8Z66	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.06	2025-04-23	To be published
	8Z67	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-04-23	To be published
	9LMO	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-07-09	To be published
	9LMP	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	2.65	2025-07-02	To be published
	8Z3Y	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2025-06-04	To be published
	8Z3Y (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.2	2025-06-04	To be published
	8Z9P	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gi1/β1/γ2	2.5	2025-07-09	To be published
	8Z9P (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.5	2025-07-09	To be published
	9IV6	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.71	2025-07-30	To be published
	9IV6 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.71	2025-07-30	To be published
	8Z9O	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.4	2025-07-16	To be published
	8Z9O (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.4	2025-07-16	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8ZD1.zip

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