psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:V13	R:R:Y165	3.79	No	No	0	4	2
2	R:R:H167	R:R:S15	6.97	Yes	No	0	3	4
3	R:R:R16	R:R:R265	4.26	No	No	0	4	1
4	R:R:R16	R:R:S268	6.59	No	No	0	4	2
5	R:R:D18	R:R:F267	4.78	No	No	5	6	4
6	R:R:D18	R:R:S268	8.83	No	No	0	6	2
7	R:R:D18	R:R:H271	13.87	No	Yes	5	6	4
8	R:R:H19	R:R:L20	14.14	No	No	0	5	3
9	R:R:H19	R:R:H82	11.94	No	No	0	5	4
10	R:R:F21	R:R:P22	4.33	No	No	0	6	5
11	R:R:F21	R:R:L25	3.65	No	No	0	6	6
12	R:R:F21	R:R:S272	3.96	No	No	0	6	5
13	R:R:P22	R:R:P23	9.74	No	No	0	5	6
14	R:R:F79	R:R:P22	7.22	No	No	0	4	5
15	R:R:L25	R:R:L279	4.15	No	No	0	6	5
16	R:R:L72	R:R:Y26	9.38	No	Yes	0	8	8
17	R:R:V76	R:R:Y26	3.79	No	Yes	0	7	8
18	R:R:F99	R:R:Y26	4.13	Yes	Yes	0	6	8
19	R:R:A275	R:R:Y26	4	No	Yes	0	4	8
20	R:R:S278	R:R:Y26	5.09	No	Yes	0	6	8
21	R:R:S278	R:R:V29	8.08	No	No	0	6	7
22	R:R:G31	R:R:I30	3.53	No	No	0	5	7
23	R:R:I30	R:R:L34	4.28	No	Yes	6	7	6
24	R:R:I30	R:R:I69	4.42	No	No	6	7	5
25	R:R:V282	R:R:V32	4.81	No	No	7	6	5
26	R:R:I69	R:R:L34	9.99	No	Yes	6	5	6
27	R:R:P285	R:R:T36	6.99	No	No	0	9	7
28	R:R:D65	R:R:N37	12.12	Yes	Yes	0	9	9
29	R:R:I69	R:R:N37	4.25	No	Yes	0	5	9
30	R:R:N37	R:R:P285	13.03	Yes	No	0	9	9
31	R:R:C289	R:R:L39	4.76	No	No	0	6	6
32	R:R:L39	R:R:V299	14.9	No	No	0	6	5
33	R:R:D298	R:R:W42	5.58	Yes	No	0	5	3
34	R:R:A302	R:R:W42	7.78	No	No	0	5	3
35	R:R:A43	R:R:D298	4.63	No	Yes	0	6	5
36	R:R:M59	R:R:Y45	3.59	No	No	0	5	1
37	R:R:Q50	R:R:R46	14.02	No	No	0	6	5
38	R:R:N52	R:R:Q47	13.2	No	No	0	7	5
39	R:R:G55	R:R:Q47	3.29	No	No	0	7	5
40	R:R:M59	R:R:V48	4.56	No	No	0	5	5
41	R:R:E53	R:R:N52	6.57	No	No	0	6	7
42	R:R:L54	R:R:N52	4.12	No	No	0	7	7
43	R:R:D116	R:R:E53	12.99	Yes	No	9	8	6
44	R:R:E53	R:R:R131	6.98	No	No	9	6	7
45	R:R:D116	R:R:L54	5.43	Yes	No	0	8	7
46	R:R:G55	R:R:L58	5.13	No	No	0	7	7
47	R:R:A136	R:R:V56	5.09	No	Yes	0	7	6
48	R:R:C112	R:R:Y57	4.03	No	Yes	0	6	7
49	R:R:D116	R:R:Y57	9.2	Yes	Yes	0	8	7
50	R:R:A136	R:R:Y57	5.34	No	Yes	0	7	7
51	R:R:V139	R:R:Y57	3.79	No	Yes	0	4	7
52	R:R:L58	R:R:Y288	3.52	No	Yes	0	7	9
53	R:R:F109	R:R:N60	12.08	Yes	No	3	7	9
54	R:R:N60	R:R:S140	11.92	No	No	3	9	6
55	R:R:N60	R:R:W144	6.78	No	Yes	3	9	9
56	R:R:D65	R:R:L61	6.79	Yes	Yes	1	9	9
57	R:R:L110	R:R:L61	5.54	Yes	Yes	1	8	9
58	R:R:D284	R:R:L61	8.14	Yes	Yes	1	9	9
59	R:R:I63	R:R:W144	3.52	No	Yes	0	5	9
60	R:R:A64	R:R:I105	6.5	No	Yes	0	8	6
61	R:R:C281	R:R:D65	4.67	No	Yes	0	8	9
62	R:R:D284	R:R:D65	3.99	Yes	Yes	1	9	9
63	R:R:L67	R:R:N102	4.12	No	Yes	0	6	8
64	R:R:L72	R:R:Y68	5.86	No	Yes	0	8	5
65	R:R:F99	R:R:Y68	8.25	Yes	Yes	0	6	5
66	R:R:N102	R:R:Y68	11.63	Yes	Yes	0	8	5
67	R:R:S278	R:R:Y68	8.9	No	Yes	0	6	5
68	R:R:C281	R:R:Y68	5.38	No	Yes	0	8	5
69	R:R:F95	R:R:T71	14.27	No	No	0	5	6
70	R:R:I98	R:R:T71	12.16	No	No	0	5	6
71	R:R:L74	R:R:W85	13.67	No	Yes	2	6	9
72	R:R:H87	R:R:L74	6.43	No	No	2	7	6
73	R:R:F95	R:R:L74	14.61	No	No	0	5	6
74	R:R:W75	R:R:Y78	8.68	Yes	Yes	0	6	5
75	R:R:G96	R:R:W75	5.63	No	Yes	0	6	6
76	R:R:F99	R:R:W75	39.09	Yes	Yes	4	6	6
77	R:R:W75	R:R:Y100	4.82	Yes	Yes	4	6	5
78	R:R:D77	R:R:H81	7.56	No	No	0	4	4
79	R:R:F79	R:R:Y78	10.32	No	Yes	0	4	5
80	R:R:D83	R:R:Y78	6.9	No	Yes	0	4	5
81	R:R:W85	R:R:Y78	4.82	Yes	Yes	0	9	5
82	R:R:E172	R:R:Y78	13.47	Yes	Yes	0	5	5
83	R:R:F79	R:R:H271	10.18	No	Yes	0	4	4
84	R:R:N84	R:R:T168	5.85	No	No	0	4	4
85	R:R:H87	R:R:W85	9.52	No	Yes	2	7	9
86	R:R:S91	R:R:W85	3.71	No	Yes	2	4	9
87	R:R:C92	R:R:W85	14.37	No	Yes	2	9	9
88	R:R:C170	R:R:W85	22.2	No	Yes	2	9	9
89	R:R:H87	R:R:S91	9.76	No	No	2	7	4
90	R:R:G88	R:R:P89	4.06	No	No	0	7	4
91	R:R:C170	R:R:C92	7.28	No	No	2	9	9
92	R:R:D158	R:R:K93	6.91	No	No	0	5	7
93	R:R:E159	R:R:K93	5.4	No	No	0	4	7
94	R:R:F97	R:R:L155	15.83	No	No	0	5	4
95	R:R:I98	R:R:N102	5.66	No	Yes	0	5	8
96	R:R:F99	R:R:Y100	9.28	Yes	Yes	4	6	5
97	R:R:F99	R:R:L274	4.87	Yes	No	4	6	5
98	R:R:F171	R:R:Y100	6.19	No	Yes	0	4	5
99	R:R:E172	R:R:Y100	3.37	Yes	Yes	0	5	5
100	R:R:L274	R:R:Y100	3.52	No	Yes	4	5	5
101	R:R:N151	R:R:S101	8.94	Yes	No	0	6	5
102	R:R:I105	R:R:N102	4.25	Yes	Yes	0	6	8
103	R:R:I103	R:R:Y104	15.71	No	Yes	0	7	7
104	R:R:I103	R:R:T277	4.56	No	No	0	7	8
105	R:R:N151	R:R:Y104	6.98	Yes	Yes	0	6	7
106	R:R:R187	R:R:Y104	10.29	No	Yes	0	5	7
107	R:R:H243	R:R:Y104	4.36	Yes	Yes	0	8	7
108	R:R:F109	R:R:I105	7.54	Yes	Yes	3	7	6
109	R:R:I105	R:R:W144	12.92	Yes	Yes	3	6	9
110	R:R:I107	R:R:P195	6.77	No	No	0	7	9
111	R:R:F109	R:R:S140	3.96	Yes	No	3	7	6
112	R:R:F109	R:R:V143	7.87	Yes	No	0	7	6
113	R:R:F109	R:R:W144	12.03	Yes	Yes	3	7	9
114	R:R:L110	R:R:M199	4.24	Yes	No	0	8	7
115	R:R:D284	R:R:L110	12.21	Yes	Yes	1	9	8
116	R:R:L110	R:R:Y288	7.03	Yes	Yes	1	8	9
117	R:R:C111	R:R:L198	4.76	No	No	0	7	5
118	R:R:I113	R:R:R117	3.76	No	No	1	8	9
119	R:R:I113	R:R:Y288	4.84	No	Yes	1	8	9
120	R:R:C202	R:R:S114	5.16	No	No	0	6	9
121	R:R:S114	R:R:Y203	13.99	No	Yes	0	9	8
122	R:R:C202	R:R:V115	3.42	No	No	0	6	5
123	R:R:D116	R:R:R131	3.57	Yes	No	9	8	7
124	R:R:R117	R:R:Y203	8.23	No	Yes	0	9	8
125	R:R:R117	R:R:Y288	6.17	No	Yes	1	9	9
126	R:R:A122	R:R:Y118	5.34	No	Yes	10	6	8
127	R:R:H123	R:R:Y118	11.98	Yes	Yes	10	6	8
128	R:R:I206	R:R:Y118	3.63	No	Yes	0	8	8
129	R:R:F127	R:R:L119	7.31	No	No	0	5	5
130	R:R:A120	R:R:R131	5.53	No	No	0	7	7
131	R:R:A122	R:R:H123	7.32	No	Yes	10	6	6
132	R:R:F127	R:R:H123	7.92	No	Yes	0	5	6
133	R:R:L125	R:R:P124	4.93	No	No	0	5	8
134	R:R:R129	R:R:R132	10.66	No	No	11	4	6
135	R:R:R129	R:R:T135	5.17	No	No	11	4	4
136	R:R:R132	R:R:T135	3.88	No	No	11	6	4
137	R:R:E147	R:R:N151	3.94	No	Yes	0	7	6
138	R:R:G149	R:R:S152	3.71	No	No	0	3	4
139	R:R:F171	R:R:P154	7.22	No	No	0	4	6
140	R:R:P154	R:R:W179	6.76	No	Yes	0	6	3
141	R:R:M183	R:R:P154	3.35	Yes	No	0	5	6
142	R:R:H157	R:R:W179	17.98	No	Yes	0	4	3
143	R:R:D158	R:R:L160	12.21	No	No	0	5	5
144	R:R:E159	R:R:F171	9.33	No	No	0	4	4
145	R:R:E159	R:R:K173	5.4	No	Yes	0	4	4
146	R:R:F161	R:R:K173	9.93	No	Yes	0	3	4
147	R:R:R162	R:R:T168	9.06	No	No	0	2	4
148	R:R:D163	R:R:H167	17.65	No	Yes	0	1	3
149	R:R:E172	R:R:F169	3.5	Yes	No	0	5	2
150	R:R:E172	R:R:H271	9.85	Yes	Yes	0	5	4
151	R:R:K173	R:R:W179	6.96	Yes	Yes	12	4	3
152	R:R:K173	R:R:V180	6.07	Yes	No	12	4	5
153	R:R:F174	R:R:P175	4.33	Yes	No	0	4	4
154	R:R:C260	R:R:F174	5.59	No	Yes	0	7	4
155	R:R:E263	R:R:F174	13.99	No	Yes	0	3	4
156	R:R:M176	R:R:V180	4.56	No	No	0	3	5
157	R:R:M176	R:R:R249	12.41	No	Yes	0	3	5
158	R:R:M176	R:R:S250	4.6	No	Yes	0	3	5
159	R:R:E177	R:R:R178	3.49	No	No	0	4	3
160	R:R:E177	R:R:W179	4.36	No	Yes	0	4	3
161	R:R:V180	R:R:W179	11.03	No	Yes	12	5	3
162	R:R:A181	R:R:S250	3.42	No	Yes	0	2	5
163	R:R:L254	R:R:W182	6.83	No	No	0	1	2
164	R:R:M183	R:R:Y186	3.59	Yes	No	0	5	4
165	R:R:M183	R:R:R187	7.44	Yes	No	0	5	5
166	R:R:N184	R:R:R187	7.23	No	No	0	5	5
167	R:R:L246	R:R:N184	16.48	No	No	0	6	5
168	R:R:N184	R:R:S250	4.47	No	Yes	0	5	5
169	R:R:V190	R:R:Y186	7.57	No	No	0	4	4
170	R:R:F189	R:R:V188	3.93	No	Yes	14	4	4
171	R:R:H243	R:R:V188	8.3	Yes	Yes	0	8	4
172	R:R:L246	R:R:V188	4.47	No	Yes	0	6	4
173	R:R:L247	R:R:V188	13.41	No	Yes	14	5	4
174	R:R:F189	R:R:L247	3.65	No	No	14	4	5
175	R:R:F192	R:R:V235	3.93	No	No	0	8	9
176	R:R:F192	R:R:F239	15	No	No	0	8	9
177	R:R:F192	R:R:H243	14.71	No	Yes	0	8	8
178	R:R:F194	R:R:P195	4.33	No	No	0	5	9
179	R:R:F194	R:R:L198	7.31	No	No	0	5	5
180	R:R:L200	R:R:W196	4.56	No	Yes	0	3	5
181	R:R:V235	R:R:W196	6.13	No	Yes	0	9	5
182	R:R:L236	R:R:W196	7.97	No	Yes	0	5	5
183	R:R:I232	R:R:L200	4.28	No	No	0	7	3
184	R:R:L201	R:R:R204	3.64	No	No	0	4	3
185	R:R:L231	R:R:Y203	7.03	No	Yes	0	7	8
186	R:R:R204	R:R:R208	6.4	No	No	0	3	4
187	R:R:K225	R:R:L207	4.23	No	No	0	5	4
188	R:R:A228	R:R:L207	4.73	No	No	0	7	4
189	R:R:K221	R:R:V210	4.55	No	No	0	6	8
190	R:R:S213	R:R:T216	9.59	No	No	0	6	3
191	R:R:E220	R:R:T216	5.64	No	No	0	5	3
192	R:R:K221	R:R:T216	4.5	No	No	0	6	3
193	R:R:E217	R:R:R218	5.82	No	No	0	4	4
194	R:R:R226	R:R:V222	3.92	No	No	0	6	5
195	R:R:K225	R:R:L229	4.23	No	No	0	5	4
196	R:R:L231	R:R:L287	6.92	No	No	0	7	8
197	R:R:L231	R:R:Y288	8.21	No	Yes	0	7	9
198	R:R:I234	R:R:L287	4.28	No	No	0	6	8
199	R:R:F239	R:R:T277	5.19	No	No	0	9	8
200	R:R:F239	R:R:N280	9.67	No	No	0	9	9
201	R:R:H243	R:R:Y242	8.71	Yes	Yes	0	8	7
202	R:R:S273	R:R:Y242	3.82	No	Yes	0	7	7
203	R:R:L274	R:R:Y242	10.55	No	Yes	0	5	7
204	R:R:T277	R:R:Y242	4.99	No	Yes	0	8	7
205	R:R:L245	R:R:S273	6.01	No	No	0	4	7
206	R:R:F262	R:R:S248	5.28	Yes	No	0	1	5
207	R:R:F262	R:R:R249	7.48	Yes	Yes	13	1	5
208	R:R:E263	R:R:R249	13.96	No	Yes	13	3	5
209	R:R:R249	R:R:Y270	19.55	Yes	No	0	5	4
210	R:R:R256	R:R:V252	6.54	No	No	0	2	2
211	R:R:F262	R:R:V252	14.42	Yes	No	0	1	2
212	R:R:L254	R:R:Y253	3.52	No	No	0	1	3
213	R:R:P257	R:R:Y253	9.74	No	No	0	1	3
214	R:R:D259	R:R:R256	15.48	No	No	0	4	2
215	R:R:D259	R:R:G261	5.03	No	No	0	4	3
216	R:R:E264	R:R:G261	6.55	No	No	0	3	3
217	R:R:E263	R:R:F262	4.66	No	Yes	13	3	1
218	R:R:F262	R:R:V266	14.42	Yes	No	0	1	5
219	R:R:F267	R:R:H271	13.58	No	Yes	5	4	4
220	R:R:F276	R:R:L279	8.53	No	No	0	7	5
221	R:R:D284	R:R:N280	12.12	Yes	No	0	9	9
222	R:R:D284	R:R:Y288	4.6	Yes	Yes	1	9	9
223	R:R:G294	R:R:S297	3.71	No	No	0	7	5
224	R:R:D298	R:R:V299	4.38	Yes	No	0	5	5
225	R:R:L303	R:R:L306	4.15	No	No	0	7	4
226	R:R:L34	R:R:P35	3.28	Yes	No	0	6	4
227	R:R:H167	R:R:Y165	3.27	Yes	No	0	3	2
228	R:R:A44	R:R:M59	3.22	No	No	0	6	5
229	R:R:A153	R:R:M183	3.22	No	Yes	0	8	5
230	R:R:V48	R:R:V56	3.21	No	Yes	8	5	6
231	R:R:F127	R:R:R126	3.21	No	No	0	5	4
232	R:R:A138	R:R:K134	3.21	No	No	0	3	4
233	R:R:C238	R:R:N280	3.15	No	No	0	7	9
234	R:R:A295	R:R:N292	3.13	No	No	0	8	8
235	R:R:I107	R:R:V235	3.07	No	No	0	7	9
236	R:R:I224	R:R:V210	3.07	No	No	0	6	8
237	R:R:K134	R:R:V137	3.04	No	No	0	4	4
238	R:R:L61	R:R:S106	3	Yes	No	1	9	9
239	R:R:L110	R:R:S106	3	Yes	No	1	8	9
240	R:R:L185	R:R:S250	3	No	Yes	0	4	5
241	R:R:L287	R:R:S230	3	No	No	0	8	5
242	R:R:L227	R:R:V291	2.98	No	No	0	7	6
243	R:R:A300	R:R:H304	2.93	No	No	0	4	4
244	R:R:G191	R:R:Y104	2.9	No	Yes	0	6	7
245	R:R:G205	R:R:Y118	2.9	No	Yes	0	4	8
246	R:R:F276	R:R:P241	2.89	No	No	0	7	9
247	R:R:I224	R:R:L207	2.85	No	No	0	6	4
248	R:R:G88	R:R:W85	2.81	No	Yes	0	7	9
249	R:R:L66	R:R:N37	2.75	No	Yes	0	7	9
250	R:R:D77	R:R:L80	2.71	No	No	0	4	4
251	R:R:C202	R:R:Y118	2.69	No	Yes	0	6	8
252	R:R:A150	R:R:Y186	2.67	No	No	0	5	4
253	R:R:A228	R:R:Y203	2.67	No	Yes	0	7	8
254	R:R:E217	R:R:E220	2.54	No	No	0	4	5
255	R:R:D83	R:R:H167	2.52	No	Yes	0	4	3
256	R:R:K134	R:R:R132	2.48	No	No	0	4	6
257	R:R:T168	R:R:W85	2.43	No	Yes	0	4	9
258	R:R:F97	R:R:N151	2.42	No	Yes	0	5	6
259	R:R:D298	R:R:R46	2.38	Yes	No	0	5	5
260	R:R:L148	R:R:W144	2.28	No	Yes	0	4	9
261	R:R:L193	R:R:W196	2.28	No	Yes	0	5	5
262	R:R:R49	R:R:Y45	2.06	No	No	0	6	1
263	R:R:G33	R:R:P35	2.03	No	No	0	8	4
264	R:R:G90	R:R:P89	2.03	No	No	0	1	4
265	R:R:A40	R:R:P285	1.87	No	No	0	8	9
266	R:R:A240	R:R:P241	1.87	No	No	0	5	9
267	R:R:G33	R:R:V32	1.84	No	No	7	8	5
268	R:R:G33	R:R:V282	1.84	No	No	7	8	6
269	R:R:A40	R:R:C289	1.81	No	No	0	8	6
270	R:R:A295	R:R:C289	1.81	No	No	0	8	6
271	R:R:A122	R:R:A209	1.79	No	No	0	6	5
272	R:R:A40	R:R:S62	1.71	No	No	0	8	8
273	R:R:G149	R:R:L148	1.71	No	No	0	3	4
274	R:R:A108	R:R:V143	1.7	No	No	0	5	6
275	R:R:A209	R:R:V121	1.7	No	No	0	5	8
276	R:R:A269	R:R:V266	1.7	No	No	0	4	5
277	R:R:G294	R:R:N292	1.7	No	No	0	7	8
278	R:R:L72	R:R:P73	1.64	No	No	0	8	9
279	R:R:E293	R:R:G294	1.64	No	No	0	5	7
280	R:R:S213	R:R:S215	1.63	No	No	0	6	4
281	R:R:S268	R:R:V17	1.62	No	No	0	2	4
282	R:R:S141	R:R:V137	1.62	No	No	0	3	4
283	R:R:A283	R:R:I234	1.62	No	No	0	6	6
284	R:R:V133	R:R:V48	1.6	No	No	8	4	5
285	R:R:V133	R:R:V56	1.6	No	Yes	8	4	6
286	R:R:V137	R:R:V56	1.6	No	Yes	0	4	6
287	R:R:C70	R:R:L34	1.59	No	Yes	0	4	6
288	R:R:C38	R:R:L66	1.59	No	No	0	2	7
289	R:R:A181	R:R:L254	1.58	No	No	0	2	1
290	R:R:I27	R:R:S24	1.55	No	No	0	4	4
291	R:R:I286	R:R:V291	1.54	No	No	0	6	6
292	R:R:H123	R:R:P124	1.53	Yes	No	0	6	8
293	R:R:L41	R:R:S62	1.5	No	No	0	7	8
294	R:R:G205	R:R:R208	1.5	No	No	0	4	4
295	R:R:L227	R:R:S230	1.5	No	No	0	7	5
296	R:R:L290	R:R:V299	1.49	No	No	0	7	5
297	R:R:I98	R:R:L94	1.43	No	No	0	5	5
298	R:R:L119	R:R:L130	1.38	No	No	0	5	5
299	R:R:N166	R:R:N84	1.36	No	No	0	5	4
300	R:R:F276	R:R:V237	1.31	No	No	0	7	6
301	R:R:H81	R:R:N84	1.28	No	No	0	4	4
302	R:R:F156	R:R:L155	1.22	No	No	0	4	4
303	R:R:D14	R:R:F174	1.19	No	Yes	0	6	4
304	R:R:Q211	R:R:R208	1.17	No	No	0	4	4
305	R:R:E293	R:R:R296	1.16	No	No	0	5	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:Y26	5.278	5	0	8
2	R:R:L34	4.785	4	6	6
3	R:R:N37	8.0375	4	0	9
4	R:R:V56	2.875	4	8	6
5	R:R:Y57	5.59	4	0	7
6	R:R:L61	5.8675	4	1	9
7	R:R:D65	6.8925	4	1	9
8	R:R:Y68	8.004	5	0	5
9	R:R:W75	14.555	4	4	6
10	R:R:Y78	8.838	5	0	5
11	R:R:W85	9.19125	8	2	9
12	R:R:F99	13.124	5	4	6
13	R:R:Y100	5.436	5	4	5
14	R:R:N102	6.415	4	0	8
15	R:R:Y104	8.048	5	0	7
16	R:R:I105	7.8025	4	3	6
17	R:R:F109	8.696	5	3	7
18	R:R:L110	6.404	5	1	8
19	R:R:D116	7.7975	4	9	8
20	R:R:Y118	5.308	5	10	8
21	R:R:H123	7.1875	4	10	6
22	R:R:W144	7.506	5	3	9
23	R:R:N151	5.57	4	0	6
24	R:R:H167	7.6025	4	0	3
25	R:R:E172	7.5475	4	0	5
26	R:R:K173	7.09	4	12	4
27	R:R:F174	6.275	4	0	4
28	R:R:W179	9.418	5	12	3
29	R:R:M183	4.4	4	0	5
30	R:R:V188	7.5275	4	14	4
31	R:R:W196	5.235	4	0	5
32	R:R:Y203	7.98	4	0	8
33	R:R:Y242	7.0175	4	0	7
34	R:R:H243	9.02	4	0	8
35	R:R:R249	13.35	4	13	5
36	R:R:S250	3.8725	4	0	5
37	R:R:F262	9.252	5	13	1
38	R:R:H271	11.87	4	5	4
39	R:R:D284	8.212	5	1	9
40	R:R:Y288	5.72833	6	1	9
41	R:R:D298	4.2425	4	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:F79	R:R:Y78	16.9954	10.32	No	Yes	0	4	5
2	R:R:E172	R:R:H271	10.8971	9.85	Yes	Yes	0	5	4
3	R:R:E172	R:R:Y78	12.6882	13.47	Yes	Yes	0	5	5
4	R:R:F21	R:R:P22	14.9647	4.33	No	No	0	6	5
5	R:R:F79	R:R:P22	18.6452	7.22	No	No	0	4	5
6	R:R:F21	R:R:L25	11.2596	3.65	No	No	0	6	6
7	R:R:F99	R:R:W75	25.6436	39.09	Yes	Yes	4	6	6
8	R:R:W75	R:R:Y78	36.4885	8.68	Yes	Yes	0	6	5
9	R:R:F99	R:R:Y68	50.3011	8.25	Yes	Yes	0	6	5
10	R:R:I69	R:R:N37	10.0338	4.25	No	Yes	0	5	9
11	R:R:D65	R:R:N37	34.2335	12.12	Yes	Yes	0	9	9
12	R:R:C281	R:R:D65	54.3226	4.67	No	Yes	0	8	9
13	R:R:C281	R:R:Y68	54.3533	5.38	No	Yes	0	8	5
14	R:R:N37	R:R:P285	22.51	13.03	Yes	No	0	9	9
15	R:R:A40	R:R:C289	17.3641	1.81	No	No	0	8	6
16	R:R:A40	R:R:P285	20.47	1.87	No	No	0	8	9
17	R:R:V48	R:R:V56	10.98	3.21	No	Yes	8	5	6
18	R:R:A136	R:R:V56	30.4055	5.09	No	Yes	0	7	6
19	R:R:A136	R:R:Y57	32.5315	5.34	No	Yes	0	7	7
20	R:R:D116	R:R:Y57	38.7281	9.2	Yes	Yes	0	8	7
21	R:R:D116	R:R:E53	20.2949	12.99	Yes	No	9	8	6
22	R:R:E53	R:R:N52	23.3948	6.57	No	No	0	6	7
23	R:R:N52	R:R:Q47	45.6498	13.2	No	No	0	7	5
24	R:R:G55	R:R:Q47	46.5837	3.29	No	No	0	7	5
25	R:R:G55	R:R:L58	47.5115	5.13	No	No	0	7	7
26	R:R:L58	R:R:Y288	48.4332	3.52	No	Yes	0	7	9
27	R:R:D284	R:R:Y288	100	4.6	Yes	Yes	1	9	9
28	R:R:D284	R:R:D65	58.7558	3.99	Yes	Yes	1	9	9
29	R:R:D116	R:R:L54	20.3011	5.43	Yes	No	0	8	7
30	R:R:L54	R:R:N52	21.318	4.12	No	No	0	7	7
31	R:R:I105	R:R:N102	15.0538	4.25	Yes	Yes	0	6	8
32	R:R:N102	R:R:Y68	20.5622	11.63	Yes	Yes	0	8	5
33	R:R:W85	R:R:Y78	25.0538	4.82	Yes	Yes	0	9	5
34	R:R:W75	R:R:Y100	12.5684	4.82	Yes	Yes	4	6	5
35	R:R:E172	R:R:Y100	24.0092	3.37	Yes	Yes	0	5	5
36	R:R:T168	R:R:W85	11.1152	2.43	No	Yes	0	4	9
37	R:R:E159	R:R:F171	18.0369	9.33	No	No	0	4	4
38	R:R:F171	R:R:Y100	40.9985	6.19	No	Yes	0	4	5
39	R:R:N151	R:R:Y104	10.5038	6.98	Yes	Yes	0	6	7
40	R:R:H243	R:R:Y104	25.2535	4.36	Yes	Yes	0	8	7
41	R:R:H243	R:R:Y242	15.3671	8.71	Yes	Yes	0	8	7
42	R:R:L274	R:R:Y242	19.4593	10.55	No	Yes	0	5	7
43	R:R:L274	R:R:Y100	10.4608	3.52	No	Yes	4	5	5
44	R:R:I103	R:R:T277	19.0108	4.56	No	No	0	7	8
45	R:R:F171	R:R:P154	22.7281	7.22	No	No	0	4	6
46	R:R:F192	R:R:V235	14.3594	3.93	No	No	0	8	9
47	R:R:F192	R:R:H243	40.7527	14.71	No	Yes	0	8	8
48	R:R:R117	R:R:Y288	33.4808	6.17	No	Yes	1	9	9
49	R:R:C202	R:R:S114	37.9969	5.16	No	No	0	6	9
50	R:R:S114	R:R:Y203	39.9355	13.99	No	Yes	0	9	8
51	R:R:R117	R:R:Y203	32.7803	8.23	No	Yes	0	9	8
52	R:R:L231	R:R:Y203	33.3979	7.03	No	Yes	0	7	8
53	R:R:L231	R:R:Y288	40.212	8.21	No	Yes	0	7	9
54	R:R:C202	R:R:Y118	34.1014	2.69	No	Yes	0	6	8
55	R:R:H123	R:R:Y118	14.1905	11.98	Yes	Yes	10	6	8
56	R:R:K134	R:R:V137	10.9954	3.04	No	No	0	4	4
57	R:R:V137	R:R:V56	15.3518	1.6	No	Yes	0	4	6
58	R:R:P154	R:R:W179	16.8141	6.76	No	Yes	0	6	3
59	R:R:E159	R:R:K173	14.3072	5.4	No	Yes	0	4	4
60	R:R:V180	R:R:W179	12.851	11.03	No	Yes	12	5	3
61	R:R:K173	R:R:V180	12.5008	6.07	Yes	No	12	4	5
62	R:R:E263	R:R:F174	10.0492	13.99	No	Yes	0	3	4
63	R:R:E263	R:R:R249	12.4086	13.96	No	Yes	13	3	5
64	R:R:M176	R:R:R249	39.3548	12.41	No	Yes	0	3	5
65	R:R:M176	R:R:V180	23.6713	4.56	No	No	0	3	5
66	R:R:M176	R:R:S250	29.7788	4.6	No	Yes	0	3	5
67	R:R:N184	R:R:S250	39.9232	4.47	No	Yes	0	5	5
68	R:R:N184	R:R:R187	28.7711	7.23	No	No	0	5	5
69	R:R:A181	R:R:S250	15.8648	3.42	No	Yes	0	2	5
70	R:R:A181	R:R:L254	12.7035	1.58	No	No	0	2	1
71	R:R:L246	R:R:V188	14.6452	4.47	No	Yes	0	6	4
72	R:R:H243	R:R:V188	17.6866	8.3	Yes	Yes	0	8	4
73	R:R:F239	R:R:T277	22.2765	5.19	No	No	0	9	8
74	R:R:G205	R:R:Y118	10.212	2.9	No	Yes	0	4	8
75	R:R:A228	R:R:L207	24.1045	4.73	No	No	0	7	4
76	R:R:A228	R:R:Y203	26.0922	2.67	No	Yes	0	7	8
77	R:R:K221	R:R:V210	14.2519	4.55	No	No	0	6	8
78	R:R:I224	R:R:V210	16.2611	3.07	No	No	0	6	8
79	R:R:I224	R:R:L207	18.1198	2.85	No	No	0	6	4
80	R:R:K221	R:R:T216	12.2366	4.5	No	No	0	6	3
81	R:R:F239	R:R:N280	59.4777	9.67	No	No	0	9	9
82	R:R:D284	R:R:N280	59.1705	12.12	Yes	No	0	9	9
83	R:R:F262	R:R:R249	22.3379	7.48	Yes	Yes	13	1	5
84	R:R:R256	R:R:V252	10.0492	6.54	No	No	0	2	2
85	R:R:F262	R:R:V252	12.5469	14.42	Yes	No	0	1	2
86	R:R:F99	R:R:Y100	24.6882	9.28	Yes	Yes	4	6	5
87	R:R:R187	R:R:Y104	31.573	10.29	No	Yes	0	5	7
88	R:R:L246	R:R:N184	13.7235	16.48	No	No	0	6	5
89	R:R:I103	R:R:Y104	18.1413	15.71	No	Yes	0	7	7
90	R:R:F192	R:R:F239	37.7296	15	No	No	0	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9JVG_nogp

PDB Summary
PDB	9JVG_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.29
Number of Linked Nodes	274
Number of Links	305
Number of Hubs	41
Number of Links mediated by Hubs	152
Number of Communities	14
Number of Nodes involved in Communities	53
Number of Links involved in Communities	62

Path Summary
Number Of Nodes in MetaPath	91
Number Of Links MetaPath	90
Number of Shortest Paths	70241
Length Of Smallest Path	3
Average Path Length	14.5344
Length of Longest Path	31
Minimum Path Strength	1.32
Average Path Strength	7.22865
Maximum Path Strength	23.885
Minimum Path Correlation	0.7
Average Path Correlation	0.929897
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	48.7734
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.6049
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• binding • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • protein binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • protein-containing complex binding • G-protein beta/gamma-subunit complex binding • pyrophosphatase activity • GTPase activity • G protein activity • ribonucleoside triphosphate phosphatase activity • molecular function regulator activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • enzyme regulator activity • molecular function activator activity • phosphorus-oxygen lyase activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • cyclase activity • adenylate cyclase regulator activity • lyase activity • adenylate cyclase activator activity • adenylate cyclase activity • cation binding • metal ion binding • developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development
Gene Ontology	Biological Process	• developmental process • multicellular organismal process • epithelium development • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • animal organ development • hair follicle placode formation • tissue development • ectodermal placode formation • anatomical structure morphogenesis • skin development • skin epidermis development • hair follicle development • molting cycle • anatomical structure development • anatomical structure formation involved in morphogenesis • ectodermal placode development • hair cycle process • system process • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of smell • cellular response to stimulus • cellular response to nitrogen compound • response to stimulus • response to endogenous stimulus • response to peptide hormone • cellular response to peptide hormone stimulus • response to oxygen-containing compound • response to nitrogen compound • response to glucagon • cellular response to oxygen-containing compound • cellular response to glucagon stimulus • cellular response to endogenous stimulus • cellular response to chemical stimulus • response to hormone • response to chemical • cellular process • cellular response to hormone stimulus • multicellular organism development • skeletal system development • bone development • system development • regulation of body fluid levels • wound healing • homotypic cell-cell adhesion • cell activation • hemostasis • biological regulation • platelet aggregation • blood coagulation • cell adhesion • cell-cell adhesion • response to stress • coagulation • regulation of biological quality • response to wounding • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • response to ketone • response to prostaglandin • response to lipid • response to alcohol • cellular response to prostaglandin stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • cellular response to lipid • response to prostaglandin E • cellular response to ketone • regulation of biological process • regulation of cellular process • signaling • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • signal transduction • homeostatic process • positive regulation of biological process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of multicellular organismal process • regulation of metabolic process • positive regulation of cellular process • protein localization • regulation of localization • establishment of protein localization • nitrogen compound transport • localization • cellular macromolecule localization • regulation of peptide hormone secretion • regulation of hormone levels • establishment of protein localization to extracellular region • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • cellular localization • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • regulation of signaling • regulation of transport • secretion • regulation of peptide transport • regulation of establishment of protein localization • export from cell • cell-cell signaling • regulation of protein transport • peptide transport • protein transport • regulation of cellular localization • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • regulation of cell communication • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • establishment of localization in cell • intracellular transport • regulation of defense response • regulation of response to external stimulus • negative regulation of inflammatory response • negative regulation of biological process • inflammatory response to antigenic stimulus • regulation of response to stress • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • defense response • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • response to external stimulus • regulation of inflammatory response • regulation of response to stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • inflammatory response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • cellular response to monoamine stimulus • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • intracellular anatomical structure • cytoplasm • cytosol • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • intracellular membrane-bounded organelle • endomembrane system • intracellular organelle • trans-Golgi network • organelle membrane • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell adhesion • regulation of cell adhesion • regulation of defense response • regulation of response to external stimulus • defense response • positive regulation of biological process • response to external stimulus • regulation of inflammatory response • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stimulus • regulation of response to stress • response to stress • positive regulation of defense response • inflammatory response • phospholipase C-activating G protein-coupled receptor signaling pathway • positive regulation of cell communication • small GTPase-mediated signal transduction • positive regulation of signal transduction • regulation of small GTPase mediated signal transduction • regulation of signal transduction • intracellular signal transduction • Rho protein signal transduction • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of cellular process • regulation of signaling • positive regulation of intracellular signal transduction • regulation of Rho protein signal transduction • positive regulation of Rho protein signal transduction • regulation of cell communication • positive regulation of small GTPase mediated signal transduction • positive regulation of signaling • regulation of vascular permeability • multicellular organismal process • system process • circulatory system process • vascular process in circulatory system • regulation of biological quality • blood circulation • cellular developmental process • connective tissue development • mesangial cell development • cell development • epithelial cell differentiation • renal system development • kidney vasculature development • multicellular organism development • pericyte cell differentiation • renal system vasculature development • mesangial cell differentiation • cell differentiation • anatomical structure development • nephron development • system development • epithelial cell differentiation involved in kidney development • blood vessel development • developmental process • epithelium development • animal organ development • tissue development • glomerular mesangium development • glomerular mesangial cell development • vasculature development • glomerular mesangial cell differentiation • circulatory system development • glomerulus development • epithelial cell development • cell differentiation involved in kidney development • glomerulus vasculature development • kidney development • regulation of developmental process • negative regulation of biological process • angiogenesis • regulation of vasculature development • tube morphogenesis • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • regulation of multicellular organismal development • blood vessel morphogenesis • tube development • negative regulation of blood vessel morphogenesis • negative regulation of developmental process • negative regulation of angiogenesis • negative regulation of vasculature development • anatomical structure morphogenesis • regulation of angiogenesis • anatomical structure formation involved in morphogenesis • negative regulation of multicellular organismal process • response to pH • response to abiotic stimulus • response to acidic pH • wound healing • angiogenesis involved in wound healing • response to wounding • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • Ras protein signal transduction • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • vacuolar membrane • lytic vacuole • vacuole • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • synapse • cell junction • G-protein beta-subunit binding • fibroblast proliferation
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	Q8BUD0
Sequence	>9JVG_nogp_Chain_R V D S R V D H L F P P S L Y I F V I G V G L P T N C L A L W A A Y R Q V R Q H N E L G V Y L M N L S I A D L L Y I C T L P L W V D Y F L H H D N W I H G P G S C K L F G F I F Y S N I Y I S I A F L C C I S V D R Y L A V A H P L R F A R L R R V K T A V A V S S V V W A T E L G A N S A P L F H D E L F R D R Y N H T F C F E K F P M E R W V A W M N L Y R V F V G F L F P W A L M L L C Y R G I L R A V Q S S V S T E R Q E K V K I K R L A L S L I A I V L V C F A P Y H A L L L S R S A V Y L G R P W D C G F E E R V F S A Y H S S L A F T S L N C V A D P I L Y C L V N E G A R S D V A K A L H N L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8ZFE	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFD	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFB	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.78	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF7	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.15	2025-02-26	10.1016/j.cell.2024.12.001
	9JVG	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-02-26	10.1016/j.cell.2024.12.001
	9JVG (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.76	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFC	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.68	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFC (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.68	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFA	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.96	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFA (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.96	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF9	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF9 (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF6	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF6 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.98	2025-02-26	10.1016/j.cell.2024.12.001
	8ZD1	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2025-02-26	10.1016/j.cell.2024.12.001
	8ZD1 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.6	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF4	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.05	2025-02-26	10.1016/j.cell.2024.12.001
	9J31	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31 (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9BIP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BIP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	8ZFJ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.1	2024-08-07	To be published
	8ZFJ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.1	2024-08-07	To be published
	9JVM	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	2.36	2025-02-26	10.1016/j.cell.2024.12.001
	9JVH	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.76	2025-02-26	10.1016/j.cell.2024.12.001

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