psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:G8	R:R:P173	6.09	No	No	0	5	4
2	R:R:C258	R:R:C9	7.28	No	No	0	8	8
3	R:R:H10	R:R:Y163	7.62	No	No	0	3	3
4	R:R:E262	R:R:H10	13.54	No	No	0	3	3
5	R:R:F265	R:R:V11	24.91	No	No	0	4	3
6	R:R:D16	R:R:S13	5.89	Yes	No	0	5	5
7	R:R:H17	R:R:S13	12.55	No	No	0	5	5
8	R:R:D16	R:R:P20	6.44	Yes	Yes	3	5	5
9	R:R:D16	R:R:F77	7.17	Yes	Yes	3	5	5
10	R:R:D16	R:R:H269	15.13	Yes	Yes	3	5	5
11	R:R:F19	R:R:P20	4.33	Yes	Yes	0	5	5
12	R:R:P20	R:R:P21	5.84	Yes	No	3	5	7
13	R:R:F77	R:R:P20	5.78	Yes	Yes	3	5	5
14	R:R:F77	R:R:P21	4.33	Yes	No	3	5	7
15	R:R:L78	R:R:P21	4.93	No	No	0	5	7
16	R:R:A273	R:R:L23	4.73	No	No	0	5	5
17	R:R:L70	R:R:Y24	10.55	No	Yes	0	8	9
18	R:R:F77	R:R:Y24	6.19	Yes	Yes	0	5	9
19	R:R:F97	R:R:Y24	5.16	Yes	Yes	0	7	9
20	R:R:A273	R:R:Y24	5.34	No	Yes	0	5	9
21	R:R:S276	R:R:Y24	5.09	No	Yes	0	7	9
22	R:R:I25	R:R:V74	4.61	No	No	0	4	7
23	R:R:F26	R:R:V30	6.55	No	No	0	4	6
24	R:R:S276	R:R:V27	6.46	No	No	0	7	7
25	R:R:V27	R:R:V280	4.81	No	No	0	7	8
26	R:R:I28	R:R:L70	4.28	No	No	0	7	8
27	R:R:I28	R:R:P71	6.77	No	No	0	7	8
28	R:R:I67	R:R:L32	4.28	No	No	0	6	6
29	R:R:P283	R:R:T34	6.99	No	No	0	9	7
30	R:R:D63	R:R:N35	9.42	Yes	No	0	9	9
31	R:R:I67	R:R:N35	4.25	No	No	0	6	9
32	R:R:N35	R:R:P283	11.4	No	No	0	9	9
33	R:R:L39	R:R:M57	4.24	No	No	0	7	5
34	R:R:L39	R:R:S60	6.01	No	No	0	7	8
35	R:R:Q47	R:R:Y43	21.42	No	No	0	6	4
36	R:R:Q47	R:R:R44	4.67	No	No	0	6	4
37	R:R:Q48	R:R:R44	10.51	No	No	0	7	4
38	R:R:N50	R:R:Q45	9.24	No	No	0	7	5
39	R:R:E51	R:R:Y55	14.59	No	Yes	1	7	7
40	R:R:D114	R:R:E51	14.29	No	No	1	8	7
41	R:R:A134	R:R:E51	4.53	No	No	1	8	7
42	R:R:I111	R:R:L52	4.28	No	No	0	9	8
43	R:R:G53	R:R:L56	5.13	No	No	0	7	8
44	R:R:A134	R:R:V54	5.09	No	Yes	0	8	7
45	R:R:C110	R:R:Y55	8.06	No	Yes	1	7	7
46	R:R:D114	R:R:Y55	6.9	No	Yes	1	8	7
47	R:R:A134	R:R:Y55	5.34	No	Yes	1	8	7
48	R:R:Y55	W:W:?1	6.23	Yes	Yes	1	7	0
49	R:R:F107	R:R:N58	14.5	Yes	No	4	8	9
50	R:R:N58	R:R:S138	7.45	No	No	4	9	7
51	R:R:N58	R:R:W142	5.65	No	Yes	4	9	9
52	R:R:L108	R:R:L59	5.54	No	No	2	8	9
53	R:R:D282	R:R:L59	6.79	Yes	No	2	9	9
54	R:R:D63	R:R:S104	4.42	Yes	No	0	9	9
55	R:R:C279	R:R:D63	4.67	No	Yes	0	9	9
56	R:R:D282	R:R:D63	5.32	Yes	Yes	0	9	9
57	R:R:L70	R:R:Y66	9.38	No	Yes	0	8	7
58	R:R:F97	R:R:Y66	10.32	Yes	Yes	0	7	7
59	R:R:N100	R:R:Y66	5.81	No	Yes	0	8	7
60	R:R:I101	R:R:Y66	4.84	No	Yes	0	8	7
61	R:R:I96	R:R:T69	4.56	No	No	0	5	7
62	R:R:L72	R:R:W83	6.83	No	Yes	6	7	9
63	R:R:H85	R:R:L72	9	No	No	6	7	7
64	R:R:F93	R:R:L72	4.87	No	No	0	6	7
65	R:R:F77	R:R:W73	5.01	Yes	No	0	5	7
66	R:R:W73	R:R:W83	7.5	No	Yes	0	7	9
67	R:R:F97	R:R:W73	16.04	Yes	No	0	7	7
68	R:R:D75	R:R:H79	7.56	No	No	0	4	4
69	R:R:F77	R:R:Y76	13.41	Yes	No	0	5	6
70	R:R:D81	R:R:Y76	11.49	No	No	0	4	6
71	R:R:W83	R:R:Y76	5.79	Yes	No	0	9	6
72	R:R:F77	R:R:H269	5.66	Yes	Yes	3	5	5
73	R:R:H79	R:R:I84	6.63	No	No	0	4	3
74	R:R:H80	R:R:N82	7.65	No	No	0	4	5
75	R:R:D81	R:R:H165	7.56	No	No	0	4	1
76	R:R:H85	R:R:W83	4.23	No	Yes	6	7	9
77	R:R:C90	R:R:W83	14.37	No	Yes	0	9	9
78	R:R:L158	R:R:W83	5.69	No	Yes	0	5	9
79	R:R:L158	R:R:P87	4.93	No	No	0	5	3
80	R:R:F93	R:R:S89	5.28	No	No	0	6	6
81	R:R:C168	R:R:C90	7.28	No	No	0	9	9
82	R:R:K91	R:R:L153	4.23	No	No	0	6	4
83	R:R:E157	R:R:K91	10.8	No	No	0	5	6
84	R:R:F93	R:R:L92	6.09	No	No	0	6	5
85	R:R:F169	R:R:G94	6.02	Yes	No	0	4	6
86	R:R:F95	R:R:T99	11.67	No	No	0	6	5
87	R:R:F95	R:R:L146	8.53	No	No	0	6	3
88	R:R:F95	R:R:L153	10.96	No	No	0	6	4
89	R:R:I96	R:R:N100	4.25	No	No	0	5	8
90	R:R:F97	R:R:Y98	10.32	Yes	No	0	7	5
91	R:R:F169	R:R:Y98	13.41	Yes	No	0	4	5
92	R:R:E170	R:R:Y98	7.86	No	No	0	4	5
93	R:R:N149	R:R:T99	14.62	No	No	0	7	5
94	R:R:I101	R:R:Y102	16.92	No	No	0	8	7
95	R:R:I101	R:R:T275	4.56	No	No	0	8	8
96	R:R:R185	R:R:Y102	16.46	No	No	0	5	7
97	R:R:H241	R:R:Y102	8.71	No	No	0	8	7
98	R:R:I103	R:R:W142	8.22	No	Yes	0	7	9
99	R:R:E145	R:R:I103	6.83	No	No	0	7	7
100	R:R:F237	R:R:I105	5.02	Yes	No	0	8	8
101	R:R:F107	R:R:S138	6.61	Yes	No	4	8	7
102	R:R:F107	R:R:V141	5.24	Yes	No	0	8	7
103	R:R:F107	R:R:W142	8.02	Yes	Yes	4	8	9
104	R:R:D282	R:R:L108	9.5	Yes	No	2	9	8
105	R:R:L108	R:R:Y286	7.03	No	Yes	2	8	9
106	R:R:C109	R:R:L196	4.76	No	No	0	8	6
107	R:R:C110	W:W:?1	6.74	No	Yes	1	7	0
108	R:R:I111	R:R:R115	7.52	No	Yes	2	9	9
109	R:R:I111	R:R:Y286	6.04	No	Yes	2	9	9
110	R:R:M197	R:R:S112	6.13	No	No	0	7	9
111	R:R:S112	R:R:S200	6.52	No	No	0	9	8
112	R:R:V113	W:W:?1	15.83	No	Yes	0	6	0
113	R:R:R115	R:R:Y201	5.14	Yes	Yes	0	9	8
114	R:R:R115	R:R:Y286	6.17	Yes	Yes	2	9	9
115	R:R:H121	R:R:Y116	7.62	Yes	Yes	0	6	8
116	R:R:Y116	W:W:?2	27.4	Yes	Yes	0	8	0
117	R:R:I204	R:R:V119	4.61	No	No	0	8	8
118	R:R:F125	R:R:H121	5.66	No	Yes	0	6	6
119	R:R:L123	R:R:P122	6.57	No	No	0	6	7
120	R:R:F125	R:R:L128	7.31	No	No	0	6	3
121	R:R:K132	R:R:R130	7.43	No	No	0	4	6
122	R:R:V137	W:W:?1	6.33	No	Yes	0	5	0
123	R:R:L146	R:R:W142	6.83	No	Yes	0	3	9
124	R:R:E145	W:W:?1	9.86	No	Yes	0	7	0
125	R:R:L153	R:R:S150	6.01	No	No	0	4	4
126	R:R:F169	R:R:P152	10.11	Yes	No	0	4	3
127	R:R:H155	R:R:W177	25.39	No	No	0	4	1
128	R:R:E157	R:R:F169	20.99	No	Yes	0	5	4
129	R:R:L158	R:R:T166	4.42	No	No	0	5	3
130	R:R:F159	R:R:F167	6.43	No	No	0	2	4
131	R:R:F159	R:R:K171	23.58	No	Yes	5	2	3
132	R:R:F159	R:R:P173	4.33	No	No	5	2	4
133	R:R:D161	R:R:Y163	10.34	No	No	0	2	3
134	R:R:D161	R:R:H165	11.35	No	No	0	2	1
135	R:R:D161	R:R:F167	9.55	No	No	0	2	4
136	R:R:E170	R:R:Y268	8.98	No	Yes	0	4	5
137	R:R:K171	R:R:P173	6.69	Yes	No	5	3	4
138	R:R:E175	R:R:K171	6.75	No	Yes	0	2	3
139	R:R:F172	R:R:R247	9.62	No	No	0	5	4
140	R:R:E261	R:R:F172	4.66	No	No	0	4	5
141	R:R:F172	R:R:F265	21.43	No	No	0	5	4
142	R:R:M174	R:R:V178	4.56	No	No	0	1	2
143	R:R:M174	R:R:Y251	16.76	No	Yes	0	1	3
144	R:R:E175	R:R:W177	9.81	No	No	0	2	1
145	R:R:G176	R:R:Y251	4.35	No	Yes	0	4	3
146	R:R:V178	R:R:W177	12.26	No	No	0	2	1
147	R:R:N182	R:R:V178	4.43	Yes	No	0	5	2
148	R:R:M181	R:R:Y184	4.79	No	No	0	4	3
149	R:R:M181	R:R:R185	7.44	No	No	0	4	5
150	R:R:N182	R:R:R185	8.44	Yes	No	0	5	5
151	R:R:L244	R:R:N182	13.73	No	Yes	0	5	5
152	R:R:N182	R:R:S248	4.47	Yes	No	0	5	5
153	R:R:V188	R:R:Y184	13.88	No	No	0	4	3
154	R:R:H241	R:R:V186	5.54	No	No	0	8	5
155	R:R:F190	R:R:F237	6.43	No	Yes	0	8	8
156	R:R:F190	R:R:H241	26.02	No	No	0	8	8
157	R:R:F192	R:R:P193	5.78	No	No	0	5	9
158	R:R:F192	R:R:L196	13.4	No	No	0	5	6
159	R:R:P193	W:W:?1	5.23	No	Yes	0	9	0
160	R:R:L234	R:R:W194	7.97	No	No	0	6	6
161	R:R:L196	W:W:?2	7.35	No	Yes	0	6	0
162	R:R:L199	W:W:?2	5.88	No	Yes	0	5	0
163	R:R:S200	W:W:?2	7.98	No	Yes	0	8	0
164	R:R:A226	R:R:Y201	5.34	No	Yes	0	7	8
165	R:R:L229	R:R:Y201	7.03	Yes	Yes	0	8	8
166	R:R:I230	R:R:Y201	7.25	No	Yes	0	7	8
167	R:R:K223	R:R:L205	5.64	No	No	0	6	5
168	R:R:R206	R:R:R209	5.33	No	No	0	3	4
169	R:R:I222	R:R:V208	4.61	No	No	0	7	8
170	R:R:S211	R:R:T214	4.8	No	Yes	0	5	3
171	R:R:E218	R:R:T214	5.64	No	Yes	0	5	3
172	R:R:K219	R:R:T214	4.5	No	Yes	0	6	3
173	R:R:E291	R:R:K221	5.4	No	No	0	5	7
174	R:R:L229	R:R:L285	5.54	Yes	No	0	8	8
175	R:R:L229	R:R:Y286	5.86	Yes	Yes	0	8	9
176	R:R:C236	R:R:N278	6.3	No	No	0	8	9
177	R:R:F237	R:R:T275	7.78	Yes	No	0	8	8
178	R:R:F237	R:R:N278	14.5	Yes	No	0	8	9
179	R:R:L244	R:R:Y240	12.89	No	Yes	0	5	6
180	R:R:Y240	R:R:Y268	5.96	Yes	Yes	0	6	5
181	R:R:S271	R:R:Y240	5.09	No	Yes	0	7	6
182	R:R:L272	R:R:Y240	9.38	No	Yes	0	5	6
183	R:R:R247	R:R:Y268	18.52	No	Yes	0	4	5
184	R:R:I250	R:R:P255	6.77	No	No	0	1	2
185	R:R:F260	R:R:I250	18.84	No	No	0	1	1
186	R:R:R254	R:R:Y251	6.17	No	Yes	0	2	3
187	R:R:E262	R:R:G259	6.55	No	No	0	3	2
188	R:R:F260	R:R:V264	6.55	No	No	0	1	4
189	R:R:F265	R:R:H269	10.18	No	Yes	0	4	5
190	R:R:H269	R:R:Y268	5.44	Yes	Yes	0	5	5
191	R:R:F274	R:R:L277	8.53	No	No	0	7	5
192	R:R:D282	R:R:N278	9.42	Yes	No	0	9	9
193	R:R:I284	R:R:L288	5.71	No	No	0	7	7
194	R:R:E291	R:R:N290	6.57	No	No	0	5	8
195	R:R:G292	R:R:N290	5.09	No	No	0	6	8
196	R:R:A293	R:R:N290	4.69	No	No	0	8	8
197	R:R:H302	R:R:R306	14.67	No	No	0	5	7
198	W:W:?1	W:W:?2	6.25	Yes	Yes	0	0	0
199	R:R:L52	R:R:L56	4.15	No	No	0	8	8
200	R:R:L225	R:R:L229	4.15	No	Yes	0	8	8
201	R:R:L301	R:R:L305	4.15	No	No	0	6	3
202	R:R:L52	R:R:N50	4.12	No	No	0	8	7
203	R:R:L65	R:R:N100	4.12	No	No	0	7	8
204	R:R:G86	R:R:P87	4.06	No	No	0	8	3
205	R:R:A120	R:R:Y116	4	No	Yes	0	7	8
206	R:R:F19	R:R:S270	3.96	Yes	No	0	5	5
207	R:R:F154	R:R:S150	3.96	No	No	0	4	4
208	R:R:F260	R:R:S246	3.96	No	No	0	1	4
209	R:R:R14	R:R:V15	3.92	No	No	0	2	4
210	R:R:A300	R:R:W40	3.89	No	No	0	3	4
211	R:R:R130	R:R:T133	3.88	No	No	0	6	3
212	R:R:R160	R:R:T166	3.88	No	No	0	1	3
213	R:R:V74	R:R:Y24	3.79	No	Yes	0	7	9
214	R:R:G189	R:R:V188	3.68	No	No	0	6	4
215	R:R:F187	R:R:L183	3.65	No	No	0	5	4
216	R:R:F307	R:R:N303	3.62	No	No	0	5	3
217	R:R:A293	R:R:C287	3.61	No	Yes	0	8	7
218	R:R:H17	R:R:H80	3.58	No	No	0	5	4
219	R:R:D257	R:R:R254	3.57	No	No	0	5	2
220	R:R:I230	R:R:W194	3.52	No	No	0	7	6
221	R:R:L252	R:R:Y251	3.52	No	Yes	0	1	3
222	R:R:Q217	R:R:R216	3.5	No	No	0	4	4
223	R:R:H121	R:R:R124	3.39	Yes	No	0	6	4
224	R:R:A106	W:W:?1	3.35	No	Yes	0	6	0
225	R:R:C236	R:R:I232	3.27	No	No	0	8	7
226	R:R:A281	R:R:I232	3.25	No	No	0	7	7
227	R:R:A42	R:R:M57	3.22	No	No	0	7	5
228	R:R:V46	R:R:V54	3.21	No	Yes	0	6	7
229	R:R:V131	R:R:V54	3.21	No	Yes	0	3	7
230	R:R:R202	R:R:R206	3.2	No	No	0	3	3
231	R:R:C36	R:R:L64	3.17	No	No	0	3	8
232	R:R:A238	R:R:L234	3.15	No	No	0	5	6
233	R:R:C258	R:R:D257	3.11	No	No	0	8	5
234	R:R:K299	R:R:S295	3.06	No	No	0	5	4
235	R:R:M57	R:R:V46	3.04	No	No	0	5	6
236	R:R:K219	R:R:V208	3.04	No	No	0	6	8
237	R:R:L183	R:R:S248	3	No	No	0	4	5
238	R:R:G203	R:R:R206	3	No	No	0	4	3
239	R:R:L37	R:R:V297	2.98	No	No	0	7	6
240	R:R:L117	R:R:V113	2.98	No	No	0	6	6
241	R:R:L243	R:R:V264	2.98	No	No	0	4	4
242	R:R:L288	R:R:V297	2.98	No	No	0	7	6
243	R:R:D296	R:R:S295	2.94	No	No	0	4	4
244	R:R:G203	R:R:Y116	2.9	No	Yes	0	4	8
245	R:R:W40	R:R:Y43	2.89	No	No	0	4	4
246	R:R:I61	R:R:L39	2.85	No	No	0	5	7
247	R:R:I222	R:R:L205	2.85	No	No	0	7	5
248	R:R:L23	R:R:L277	2.77	No	No	0	5	5
249	R:R:L32	R:R:L64	2.77	No	No	0	6	8
250	R:R:A118	R:R:R129	2.77	No	No	0	8	7
251	R:R:A148	R:R:Y184	2.67	No	No	0	5	3
252	R:R:A179	R:R:Y251	2.67	No	Yes	0	1	3
253	R:R:R49	R:R:V131	2.62	No	No	0	6	3
254	R:R:F237	R:R:V233	2.62	Yes	No	0	8	9
255	R:R:A62	R:R:W142	2.59	No	Yes	0	8	9
256	R:R:V46	R:R:Y43	2.52	No	No	0	6	4
257	R:R:D75	R:R:H85	2.52	No	No	0	4	7
258	R:R:I204	R:R:R115	2.51	No	Yes	0	8	9
259	R:R:F26	R:R:L277	2.44	No	No	0	4	5
260	R:R:F190	R:R:L191	2.44	No	No	0	8	4
261	R:R:F307	R:R:L304	2.44	No	No	0	5	4
262	R:R:D114	R:R:R129	2.38	No	No	0	8	7
263	R:R:E291	R:R:R294	2.33	No	No	0	5	8
264	R:R:L198	R:R:W194	2.28	No	No	0	5	6
265	R:R:R162	R:R:Y163	2.06	No	No	0	4	3
266	R:R:G31	R:R:P33	2.03	No	No	0	8	5
267	R:R:G253	R:R:P255	2.03	No	No	0	3	2
268	R:R:A38	R:R:P283	1.87	No	No	0	9	9
269	R:R:A151	R:R:P152	1.87	No	No	0	7	3
270	R:R:A238	R:R:P239	1.87	No	No	0	5	9
271	R:R:G147	R:R:S150	1.86	No	No	0	4	4
272	R:R:G292	R:R:S295	1.86	No	No	0	6	4
273	R:R:G31	R:R:V280	1.84	No	No	0	8	8
274	R:R:A38	R:R:C287	1.81	No	Yes	0	9	7
275	R:R:A41	R:R:C287	1.81	No	Yes	0	7	7
276	R:R:A120	R:R:A207	1.79	No	No	0	7	5
277	R:R:C287	R:R:V297	1.71	Yes	No	0	7	6
278	R:R:S139	R:R:V135	1.62	No	No	0	5	4
279	R:R:S213	R:R:V212	1.62	No	No	0	3	3
280	R:R:V135	R:R:V54	1.6	No	Yes	0	4	7
281	R:R:S213	R:R:T214	1.6	No	Yes	0	3	3
282	R:R:C68	R:R:L32	1.59	No	No	0	5	6
283	R:R:T144	R:R:V140	1.59	No	No	0	5	3
284	R:R:A226	R:R:L205	1.58	No	No	0	7	5
285	R:R:A267	R:R:L243	1.58	No	No	0	5	4
286	R:R:I284	R:R:V289	1.54	No	No	0	7	6
287	R:R:H121	R:R:P122	1.53	Yes	No	0	6	7
288	R:R:L225	R:R:S228	1.5	No	No	0	8	6
289	R:R:L285	R:R:S228	1.5	No	No	0	8	6
290	R:R:L243	R:R:S271	1.5	No	No	0	4	7
291	R:R:G253	R:R:R254	1.5	No	No	0	3	2
292	R:R:D16	R:R:S266	1.47	Yes	No	0	5	2
293	R:R:E145	R:R:T144	1.41	No	No	0	7	5
294	R:R:K223	R:R:L227	1.41	No	No	0	6	5
295	R:R:G259	R:R:W256	1.41	No	No	0	2	3
296	R:R:D156	R:R:K171	1.38	No	Yes	0	5	3
297	R:R:L183	R:R:L245	1.38	No	No	0	4	6
298	R:R:A220	R:R:R224	1.38	No	No	0	5	6
299	R:R:F19	R:R:S22	1.32	Yes	No	0	5	5
300	R:R:F19	R:R:V15	1.31	Yes	No	0	5	4
301	R:R:F274	R:R:V235	1.31	No	No	0	7	5
302	R:R:R263	R:R:V264	1.31	No	No	0	3	4
303	R:R:H17	R:R:L18	1.29	No	No	0	5	4
304	R:R:H302	R:R:N303	1.28	No	No	0	5	3
305	R:R:E215	R:R:E218	1.27	No	No	0	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:D16	7.22	5	3	5
2	R:R:F19	2.73	4	0	5
3	R:R:P20	5.5975	4	3	5
4	R:R:Y24	6.02	6	0	9
5	R:R:V54	3.2775	4	0	7
6	R:R:Y55	8.224	5	1	7
7	R:R:D63	5.9575	4	0	9
8	R:R:Y66	7.5875	4	0	7
9	R:R:F77	6.79286	7	3	5
10	R:R:W83	7.40167	6	6	9
11	R:R:F97	10.46	4	0	7
12	R:R:F107	8.5925	4	4	8
13	R:R:R115	5.335	4	2	9
14	R:R:Y116	10.48	4	0	8
15	R:R:H121	4.55	4	0	6
16	R:R:W142	6.262	5	4	9
17	R:R:F169	12.6325	4	0	4
18	R:R:K171	9.6	4	5	3
19	R:R:N182	7.7675	4	0	5
20	R:R:Y201	6.19	4	0	8
21	R:R:T214	4.135	4	0	3
22	R:R:L229	5.645	4	0	8
23	R:R:F237	7.27	5	0	8
24	R:R:Y240	8.33	4	0	6
25	R:R:Y251	6.694	5	0	3
26	R:R:Y268	9.725	4	0	5
27	R:R:H269	9.1025	4	3	5
28	R:R:D282	7.7575	4	2	9
29	R:R:Y286	6.275	4	2	9
30	R:R:C287	2.235	4	0	7
31	W:W:?1	7.4775	8	1	0
32	W:W:?2	10.972	5	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:M174	R:R:Y251	14.512	16.76	No	Yes	0	1	3
2	R:R:M174	R:R:V178	15.9101	4.56	No	No	0	1	2
3	R:R:V178	R:R:W177	10.4383	12.26	No	No	0	2	1
4	R:R:D161	R:R:Y163	15.1703	10.34	No	No	0	2	3
5	R:R:H10	R:R:Y163	10.1385	7.62	No	No	0	3	3
6	R:R:F77	R:R:H269	13.3062	5.66	Yes	Yes	3	5	5
7	R:R:F77	R:R:Y76	25.3935	13.41	Yes	No	0	5	6
8	R:R:D81	R:R:Y76	27.6422	11.49	No	No	0	4	6
9	R:R:D81	R:R:H165	25.1849	7.56	No	No	0	4	1
10	R:R:D161	R:R:H165	22.7994	11.35	No	No	0	2	1
11	R:R:D16	R:R:F77	12.4752	7.17	Yes	Yes	3	5	5
12	R:R:D16	R:R:S13	11.0771	5.89	Yes	No	0	5	5
13	R:R:F77	R:R:P20	11.9244	5.78	Yes	Yes	3	5	5
14	R:R:F19	R:R:P20	10.8489	4.33	Yes	Yes	0	5	5
15	R:R:A273	R:R:Y24	10.8555	5.34	No	Yes	0	5	9
16	R:R:F77	R:R:Y24	35.9883	6.19	Yes	Yes	0	5	9
17	R:R:L70	R:R:Y24	19.5698	10.55	No	Yes	0	8	9
18	R:R:F97	R:R:Y24	30.9239	5.16	Yes	Yes	0	7	9
19	R:R:F97	R:R:W73	39.0745	16.04	Yes	No	0	7	7
20	R:R:F77	R:R:W73	22.9395	5.01	Yes	No	0	5	7
21	R:R:W73	R:R:W83	23.3534	7.5	No	Yes	0	7	9
22	R:R:W83	R:R:Y76	12.247	5.79	Yes	No	0	9	6
23	R:R:N182	R:R:V178	26.1333	4.43	Yes	No	0	5	2
24	R:R:N182	R:R:R185	28.9848	8.44	Yes	No	0	5	5
25	R:R:R185	R:R:Y102	34.6	16.46	No	No	0	5	7
26	R:R:I101	R:R:Y102	24.4778	16.92	No	No	0	8	7
27	R:R:I101	R:R:T275	89.8843	4.56	No	No	0	8	8
28	R:R:F237	R:R:T275	89.2456	7.78	Yes	No	0	8	8
29	R:R:F237	R:R:N278	100	14.5	Yes	No	0	8	9
30	R:R:D282	R:R:N278	96.6368	9.42	Yes	No	0	9	9
31	R:R:D282	R:R:D63	36.8226	5.32	Yes	Yes	0	9	9
32	R:R:D63	R:R:N35	33.0976	9.42	Yes	No	0	9	9
33	R:R:H241	R:R:Y102	17.2658	8.71	No	No	0	8	7
34	R:R:F190	R:R:H241	16.0404	26.02	No	No	0	8	8
35	R:R:F190	R:R:F237	16.2555	6.43	No	Yes	0	8	8
36	R:R:N35	R:R:P283	25.4717	11.4	No	No	0	9	9
37	R:R:F97	R:R:Y98	58.3314	10.32	Yes	No	0	7	5
38	R:R:F169	R:R:Y98	68.5384	13.41	Yes	No	0	4	5
39	R:R:E157	R:R:F169	65.9182	20.99	No	Yes	0	5	4
40	R:R:E157	R:R:K91	65.2306	10.8	No	No	0	5	6
41	R:R:K91	R:R:L153	64.5364	4.23	No	No	0	6	4
42	R:R:F95	R:R:L153	61.6946	10.96	No	No	0	6	4
43	R:R:F95	R:R:L146	59.4949	8.53	No	No	0	6	3
44	R:R:L146	R:R:W142	58.7486	6.83	No	Yes	0	3	9
45	R:R:I103	R:R:W142	53.342	8.22	No	Yes	0	7	9
46	R:R:E145	R:R:I103	52.5436	6.83	No	No	0	7	7
47	R:R:E145	W:W:?1	50.1092	9.86	No	Yes	0	7	0
48	R:R:Y55	W:W:?1	24.5755	6.23	Yes	Yes	1	7	0
49	R:R:A134	R:R:Y55	19.5763	5.34	No	Yes	1	8	7
50	R:R:A134	R:R:V54	18.7584	5.09	No	Yes	0	8	7
51	R:R:V46	R:R:V54	13.4137	3.21	No	Yes	0	6	7
52	R:R:L244	R:R:N182	19.2146	13.73	No	Yes	0	5	5
53	R:R:L244	R:R:Y240	19.0191	12.89	No	Yes	0	5	6
54	R:R:Y240	R:R:Y268	18.6932	5.96	Yes	Yes	0	6	5
55	R:R:E170	R:R:Y268	14.1665	8.98	No	Yes	0	4	5
56	R:R:E170	R:R:Y98	14.5902	7.86	No	No	0	4	5
57	R:R:D282	R:R:L108	67.9974	9.5	Yes	No	2	9	8
58	R:R:L108	R:R:Y286	67.0882	7.03	No	Yes	2	8	9
59	R:R:I101	R:R:Y66	87.3424	4.84	No	Yes	0	8	7
60	W:W:?1	W:W:?2	21.6229	6.25	Yes	Yes	0	0	0
61	R:R:R115	R:R:Y286	28.0919	6.17	Yes	Yes	2	9	9
62	R:R:R115	R:R:Y201	25.0155	5.14	Yes	Yes	0	9	8
63	R:R:L229	R:R:Y286	30.6502	5.86	Yes	Yes	0	8	9
64	R:R:L229	R:R:Y201	24.846	7.03	Yes	Yes	0	8	8
65	R:R:Y116	W:W:?2	14.4435	27.4	Yes	Yes	0	8	0
66	R:R:I230	R:R:Y201	15.3788	7.25	No	Yes	0	7	8
67	R:R:I230	R:R:W194	12.8532	3.52	No	No	0	7	6
68	R:R:A226	R:R:Y201	32.612	5.34	No	Yes	0	7	8
69	R:R:A226	R:R:L205	30.1939	1.58	No	No	0	7	5
70	R:R:I222	R:R:L205	22.8255	2.85	No	No	0	7	5
71	R:R:I222	R:R:V208	20.4823	4.61	No	No	0	7	8
72	R:R:K219	R:R:V208	17.9469	3.04	No	No	0	6	8
73	R:R:K219	R:R:T214	15.4049	4.5	No	Yes	0	6	3
74	R:R:A293	R:R:N290	10.9923	4.69	No	No	0	8	8
75	R:R:A293	R:R:C287	12.3513	3.61	No	Yes	0	8	7
76	R:R:A38	R:R:C287	21.5708	1.81	No	Yes	0	9	7
77	R:R:A38	R:R:P283	22.8776	1.87	No	No	0	9	9
78	R:R:S271	R:R:Y240	11.2205	5.09	No	Yes	0	7	6
79	R:R:H269	R:R:Y268	11.9407	5.44	Yes	Yes	0	5	5
80	R:R:L70	R:R:Y66	19.9316	9.38	No	Yes	0	8	7
81	R:R:F97	R:R:Y66	71.24	10.32	Yes	Yes	0	7	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:C110	R:R:Y55	8.06	1	No	Yes	7	7	2	2
R:R:Y55	W:W:?1	6.23	1	Yes	Yes	7	0	2	1
R:R:C109	R:R:L196	4.76	0	No	No	8	6	2	1
R:R:C110	W:W:?1	6.74	1	No	Yes	7	0	2	1
R:R:S112	R:R:S200	6.52	0	No	No	9	8	2	1
R:R:V113	W:W:?1	15.83	0	No	Yes	6	0	2	1
R:R:H121	R:R:Y116	7.62	0	Yes	Yes	6	8	2	1
R:R:Y116	W:W:?2	27.4	0	Yes	Yes	8	0	1	0
R:R:V137	W:W:?1	6.33	0	No	Yes	5	0	2	1
R:R:E145	W:W:?1	9.86	0	No	Yes	7	0	2	1
R:R:F192	R:R:P193	5.78	0	No	No	5	9	2	2
R:R:F192	R:R:L196	13.4	0	No	No	5	6	2	1
R:R:P193	W:W:?1	5.23	0	No	Yes	9	0	2	1
R:R:L196	W:W:?2	7.35	0	No	Yes	6	0	1	0
R:R:L199	W:W:?2	5.88	0	No	Yes	5	0	1	0
R:R:S200	W:W:?2	7.98	0	No	Yes	8	0	1	0
W:W:?1	W:W:?2	6.25	1	Yes	Yes	0	0	1	0
R:R:A120	R:R:Y116	4	0	No	Yes	7	8	2	1
R:R:A106	W:W:?1	3.35	0	No	Yes	6	0	2	1
R:R:G203	R:R:Y116	2.9	0	No	Yes	4	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
R:R:E51	R:R:Y55	14.59	1	No	Yes	7	7	2	1
R:R:D114	R:R:E51	14.29	1	No	No	8	7	2	2
R:R:A134	R:R:E51	4.53	1	No	No	8	7	2	2
R:R:C110	R:R:Y55	8.06	1	No	Yes	7	7	1	1
R:R:D114	R:R:Y55	6.9	1	No	Yes	8	7	2	1
R:R:A134	R:R:Y55	5.34	1	No	Yes	8	7	2	1
R:R:Y55	W:W:?1	6.23	1	Yes	Yes	7	0	1	0
R:R:E145	R:R:I103	6.83	0	No	No	7	7	1	2
R:R:C110	W:W:?1	6.74	1	No	Yes	7	0	1	0
R:R:V113	W:W:?1	15.83	0	No	Yes	6	0	1	0
R:R:Y116	W:W:?2	27.4	0	Yes	Yes	8	0	2	1
R:R:V137	W:W:?1	6.33	0	No	Yes	5	0	1	0
R:R:E145	W:W:?1	9.86	0	No	Yes	7	0	1	0
R:R:F192	R:R:P193	5.78	0	No	No	5	9	2	1
R:R:F192	R:R:L196	13.4	0	No	No	5	6	2	2
R:R:P193	W:W:?1	5.23	0	No	Yes	9	0	1	0
R:R:L196	W:W:?2	7.35	0	No	Yes	6	0	2	1
R:R:L199	W:W:?2	5.88	0	No	Yes	5	0	2	1
R:R:S200	W:W:?2	7.98	0	No	Yes	8	0	2	1
W:W:?1	W:W:?2	6.25	1	Yes	Yes	0	0	0	1
R:R:A106	W:W:?1	3.35	0	No	Yes	6	0	1	0
R:R:L117	R:R:V113	2.98	0	No	No	6	6	2	1
R:R:E145	R:R:T144	1.41	0	No	No	7	5	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9JCQ_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	4.22
Number of Linked Nodes	287
Number of Links	305
Number of Hubs	32
Number of Links mediated by Hubs	124
Number of Communities	6
Number of Nodes involved in Communities	27
Number of Links involved in Communities	33

Path Summary
Number Of Nodes in MetaPath	82
Number Of Links MetaPath	81
Number of Shortest Paths	64051
Length Of Smallest Path	3
Average Path Length	16.2871
Length of Longest Path	38
Minimum Path Strength	1.315
Average Path Strength	8.09929
Maximum Path Strength	23.17
Minimum Path Correlation	0.7
Average Path Correlation	0.937575
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.0303
Average % Of Corr. Nodes	49.2026
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	36.7987
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell adhesion • regulation of cell adhesion • regulation of defense response • regulation of response to external stimulus • defense response • positive regulation of biological process • response to external stimulus • regulation of inflammatory response • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stimulus • regulation of response to stress • response to stress • positive regulation of defense response • inflammatory response • phospholipase C-activating G protein-coupled receptor signaling pathway • response to pH • cellular response to pH • response to abiotic stimulus • cellular response to acidic pH • response to acidic pH • cellular response to abiotic stimulus • cellular response to environmental stimulus • positive regulation of cell communication • small GTPase-mediated signal transduction • positive regulation of signal transduction • regulation of small GTPase mediated signal transduction • regulation of signal transduction • intracellular signal transduction • Rho protein signal transduction • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of cellular process • regulation of signaling • positive regulation of intracellular signal transduction • regulation of Rho protein signal transduction • positive regulation of Rho protein signal transduction • regulation of cell communication • positive regulation of small GTPase mediated signal transduction • positive regulation of signaling • regulation of vascular permeability • multicellular organismal process • system process • circulatory system process • vascular process in circulatory system • regulation of biological quality • blood circulation • cellular developmental process • connective tissue development • mesangial cell development • cell development • epithelial cell differentiation • renal system development • kidney vasculature development • multicellular organism development • pericyte cell differentiation • renal system vasculature development • mesangial cell differentiation • cell differentiation • anatomical structure development • nephron development • system development • epithelial cell differentiation involved in kidney development • blood vessel development • developmental process • epithelium development • animal organ development • tissue development • glomerular mesangium development • glomerular mesangial cell development • vasculature development • glomerular mesangial cell differentiation • circulatory system development • glomerulus development • epithelial cell development • cell differentiation involved in kidney development • glomerulus vasculature development • kidney development • regulation of developmental process • negative regulation of biological process • angiogenesis • regulation of vasculature development • tube morphogenesis • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • regulation of multicellular organismal development • blood vessel morphogenesis • tube development • negative regulation of blood vessel morphogenesis • negative regulation of developmental process • negative regulation of angiogenesis • negative regulation of vasculature development • anatomical structure morphogenesis • regulation of angiogenesis • anatomical structure formation involved in morphogenesis • negative regulation of multicellular organismal process • wound healing • angiogenesis involved in wound healing • response to wounding • cell periphery • cellular anatomical structure • plasma membrane • membrane • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • Ras protein signal transduction • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_W_
PDB Residues	W:W:?1 W:W:?2
Environment Details	Open EMBL-EBI Page
Code	_W_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P46093
Sequence	>9JCQ_nogp_Chain_R G C H V D S R V D H L F P P S L Y I F V I G V G L P T N C L A L W A A Y R Q V Q Q R N E L G V Y L M N L S I A D L L Y I C T L P L W V D Y F L H H D N W I H G P G S C K L F G F I F Y T N I Y I S I A F L C C I S V D R Y L A V A H P L R F A R L R R V K T A V A V S S V V W A T E L G A N S A P L F H D E L F R D R Y N H T F C F E K F P M E G W V A W M N L Y R V F V G F L F P W A L M L L S Y R G I L R A V R G S V S T E R Q E K A K I K R L A L S L I A I V L V C F A P Y H V L L L S R S A I Y L G R P W D C G F E E R V F S A Y H S S L A F T S L N C V A D P I L Y C L V N E G A R S D V A K A L H N L L R F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8ZFZ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9BIP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BIP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9J31	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31 (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZD1	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZD1 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF4	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.05	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF7	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.15	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9 (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFB	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.78	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFD	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFE	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVH	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVM	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	2.36	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8Z3M	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2025-04-23	To be published
	8Z3M (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	To be published
	8Z3Q	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-04-23	To be published
	8Z3Q (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.76	2025-04-23	To be published
	8Z65	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-04-23	To be published
	8Z65 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.98	2025-04-23	To be published
	8Z66	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.06	2025-04-23	To be published
	8Z67	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-04-23	To be published
	8ZCE	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCE (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFU	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	3.23	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi2-G13)/β1/γ2	3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8Z3Y	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2025-06-04	To be published
	8Z3Y (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.2	2025-06-04	To be published
	9LMP	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	2.65	2025-07-02	To be published
	8Z9P	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gi1/β1/γ2	2.5	2025-07-09	To be published
	8Z9P (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.5	2025-07-09	To be published
	9JCO	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCO (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCP	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs-CtGq)/β1/γ2	2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9LMO	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-07-09	To be published
	8Z9O	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.4	2025-07-16	To be published
	8Z9O (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.4	2025-07-16	To be published
	9IV6	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.71	2025-07-30	To be published
	9IV6 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.71	2025-07-30	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9JCQ_nogp.zip

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