psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:L12	A:A:T11	2.95	No	No	0	2	4
2	A:A:D16	A:A:L12	4.07	No	No	0	4	2
3	A:A:K17	A:A:L12	2.82	No	No	0	3	2
4	A:A:D16	A:A:S13	8.83	No	No	0	4	7
5	A:A:V20	B:B:N88	5.91	No	Yes	0	3	7
6	A:A:R22	B:B:H91	3.39	No	Yes	0	5	5
7	A:A:E27	A:A:S23	2.87	No	No	3	6	7
8	A:A:S23	B:B:N88	7.45	No	Yes	3	7	7
9	A:A:S23	B:B:K89	7.65	No	Yes	3	7	9
10	A:A:I26	B:B:K89	8.72	No	Yes	0	9	9
11	A:A:E27	B:B:K89	9.45	No	Yes	3	6	9
12	A:A:K28	A:A:K32	5.75	No	No	0	4	4
13	A:A:K32	A:A:Q29	2.71	No	No	0	4	4
14	A:A:D33	A:A:Q29	7.83	No	No	0	5	4
15	A:A:L30	B:B:K78	2.82	No	Yes	0	5	8
16	A:A:L30	B:B:K89	2.82	No	Yes	0	5	9
17	A:A:D33	B:B:K78	6.91	No	Yes	0	5	8
18	A:A:K34	B:B:L55	7.05	No	No	0	4	6
19	A:A:Q35	R:R:R132	5.84	No	Yes	0	3	6
20	A:A:R42	A:A:Y37	19.55	No	No	0	9	4
21	A:A:Y37	B:B:L55	2.34	No	No	0	4	6
22	A:A:Y37	B:B:A56	2.67	No	No	0	4	7
23	A:A:R38	R:R:A128	2.77	No	No	0	4	4
24	A:A:R38	R:R:R132	9.6	No	Yes	0	4	6
25	A:A:N218	A:A:T40	7.31	No	No	0	4	7
26	A:A:H220	A:A:T40	4.11	Yes	No	0	7	7
27	A:A:H41	A:A:V217	2.77	Yes	Yes	1	6	5
28	A:A:F219	A:A:H41	5.66	Yes	Yes	1	8	6
29	A:A:H41	A:A:T242	5.48	Yes	No	1	6	8
30	A:A:H41	A:A:I383	5.3	Yes	Yes	1	6	8
31	A:A:H41	R:R:L125	7.71	Yes	Yes	1	6	5
32	A:A:H220	A:A:R42	4.51	Yes	No	2	7	9
33	A:A:F222	A:A:R42	4.28	Yes	No	2	7	9
34	A:A:F212	A:A:L43	2.44	Yes	No	1	9	7
35	A:A:I245	A:A:L43	5.71	Yes	No	1	7	7
36	A:A:I375	A:A:L43	2.85	Yes	No	1	9	7
37	A:A:L44	A:A:L46	5.54	No	Yes	0	9	8
38	A:A:F238	A:A:L44	17.05	Yes	No	0	9	9
39	A:A:I244	A:A:L44	4.28	Yes	No	0	8	9
40	A:A:K53	A:A:L45	8.46	Yes	Yes	0	9	8
41	A:A:L45	A:A:M221	2.83	Yes	No	0	8	8
42	A:A:D223	A:A:L45	6.79	No	Yes	0	9	8
43	A:A:I245	A:A:L45	2.85	Yes	Yes	0	7	8
44	A:A:L46	A:A:R231	3.64	Yes	Yes	2	8	9
45	A:A:I276	A:A:L46	4.28	Yes	Yes	2	8	8
46	A:A:G47	A:A:K53	3.49	No	Yes	0	9	9
47	A:A:A48	A:A:N50	3.13	No	Yes	0	8	9
48	A:A:D49	A:A:N50	5.39	No	Yes	1	8	9
49	A:A:D49	A:A:R265	8.34	No	Yes	1	8	9
50	A:A:N50	A:A:S51	2.98	Yes	No	1	9	9
51	A:A:D249	A:A:N50	8.08	Yes	Yes	1	8	9
52	A:A:D252	A:A:N50	6.73	No	Yes	1	8	9
53	A:A:N50	A:A:R265	12.05	Yes	Yes	1	9	9
54	A:A:K53	A:A:S51	3.06	Yes	No	1	9	9
55	A:A:S51	A:A:V247	6.46	No	Yes	1	9	7
56	A:A:G52	A:A:K293	3.49	No	Yes	0	9	9
57	A:A:K53	A:A:V247	3.04	Yes	Yes	1	9	7
58	A:A:S366	A:A:T55	9.59	No	No	0	9	9
59	A:A:I56	A:A:V247	3.07	No	Yes	1	7	7
60	A:A:F290	A:A:I56	3.77	Yes	No	1	9	7
61	A:A:I56	A:A:N292	4.25	No	Yes	1	7	9
62	A:A:T210	A:A:V57	4.76	No	No	0	7	7
63	A:A:M221	A:A:V57	3.04	No	No	0	8	7
64	A:A:I62	A:A:K58	2.91	No	No	0	9	9
65	A:A:I62	A:A:Q59	4.12	No	No	1	9	9
66	A:A:Q59	A:A:Y63	2.25	No	Yes	1	9	9
67	A:A:Q59	A:A:V367	12.89	No	No	0	9	9
68	A:A:H64	A:A:M60	5.25	Yes	No	1	8	9
69	A:A:F212	A:A:M60	12.44	Yes	No	1	9	9
70	A:A:A372	A:A:M60	3.22	No	No	1	8	9
71	A:A:I62	A:A:Y63	2.42	No	Yes	1	9	9
72	A:A:H64	A:A:Y63	3.27	Yes	Yes	1	8	9
73	A:A:T369	A:A:Y63	7.49	No	Yes	0	9	9
74	A:A:F212	A:A:H64	3.39	Yes	Yes	1	9	8
75	A:A:A372	A:A:H64	2.93	No	Yes	1	8	8
76	A:A:S205	A:A:V202	6.46	No	No	0	7	6
77	A:A:G206	B:B:N119	5.09	No	No	0	8	9
78	A:A:F222	A:A:I207	2.51	Yes	No	2	7	9
79	A:A:I207	B:B:W99	4.7	No	Yes	2	9	9
80	A:A:I207	B:B:L117	2.85	No	Yes	2	9	9
81	A:A:D223	A:A:F208	8.36	No	No	0	9	5
82	A:A:F208	A:A:G225	3.01	No	No	0	5	9
83	A:A:E209	A:A:K211	13.5	No	No	2	9	4
84	A:A:E209	A:A:H220	11.08	No	Yes	2	9	7
85	A:A:E209	A:A:F222	5.83	No	Yes	2	9	7
86	A:A:H220	A:A:K211	13.1	Yes	No	2	7	4
87	A:A:F212	A:A:F219	15	Yes	Yes	1	9	8
88	A:A:F212	A:A:M221	2.49	Yes	No	0	9	8
89	A:A:A372	A:A:F212	2.77	No	Yes	1	8	9
90	A:A:F212	A:A:I375	2.51	Yes	Yes	1	9	9
91	A:A:K216	A:A:Q213	4.07	No	No	0	4	3
92	A:A:N218	A:A:Q213	5.28	No	No	0	4	3
93	A:A:D215	A:A:V214	5.84	No	No	1	5	6
94	A:A:R373	A:A:V214	5.23	Yes	No	1	5	6
95	A:A:F376	A:A:V214	9.18	Yes	No	1	8	6
96	A:A:D215	A:A:R373	10.72	No	Yes	1	5	5
97	A:A:D215	A:A:F376	4.78	No	Yes	1	5	8
98	A:A:F219	A:A:V217	3.93	Yes	Yes	1	8	5
99	A:A:F376	A:A:V217	3.93	Yes	Yes	1	8	5
100	A:A:V217	R:R:L125	4.47	Yes	Yes	1	5	5
101	A:A:V217	R:R:R126	3.92	Yes	No	0	5	4
102	A:A:F219	A:A:F376	4.29	Yes	Yes	1	8	8
103	A:A:C379	A:A:F219	4.19	No	Yes	0	8	8
104	A:A:F222	A:A:H220	14.71	Yes	Yes	2	7	7
105	A:A:F222	B:B:S98	2.64	Yes	No	2	7	8
106	A:A:F222	B:B:W99	21.05	Yes	Yes	2	7	9
107	A:A:Q227	A:A:V224	4.3	Yes	No	2	9	9
108	A:A:V224	A:A:W234	11.03	No	Yes	2	9	9
109	A:A:Q227	A:A:W234	6.57	Yes	Yes	2	9	9
110	A:A:Q227	B:B:N119	6.6	Yes	No	0	9	9
111	A:A:Q227	B:B:Y145	6.76	Yes	Yes	2	9	8
112	A:A:E230	A:A:R228	6.98	No	No	0	9	9
113	A:A:R228	B:B:T164	6.47	No	No	0	9	6
114	A:A:R228	B:B:D186	9.53	No	Yes	0	9	9
115	A:A:E230	A:A:R232	9.3	No	No	0	9	8
116	A:A:R231	A:A:W234	8	Yes	Yes	2	9	9
117	A:A:D272	A:A:R231	5.96	No	Yes	0	8	9
118	A:A:I276	A:A:R231	8.77	Yes	Yes	2	8	9
119	A:A:R232	B:B:C204	4.18	No	Yes	2	8	7
120	A:A:R232	B:B:D228	7.15	No	Yes	2	8	9
121	A:A:K233	A:A:Q236	2.71	Yes	No	2	9	8
122	A:A:K233	B:B:Y145	3.58	Yes	Yes	2	9	8
123	A:A:K233	B:B:M188	8.64	Yes	No	2	9	8
124	A:A:K233	B:B:C204	3.23	Yes	Yes	2	9	7
125	A:A:K233	B:B:D228	11.06	Yes	Yes	2	9	9
126	A:A:K233	B:B:N230	5.6	Yes	No	2	9	9
127	A:A:K233	B:B:D246	4.15	Yes	Yes	2	9	9
128	A:A:F238	A:A:W234	4.01	Yes	Yes	2	9	9
129	A:A:W234	B:B:L117	2.28	Yes	Yes	2	9	9
130	A:A:W234	B:B:Y145	4.82	Yes	Yes	2	9	8
131	A:A:I235	A:A:N279	4.25	No	Yes	2	9	8
132	A:A:I235	A:A:L282	5.71	No	No	2	9	9
133	A:A:Q236	A:A:W281	17.52	No	Yes	2	8	5
134	A:A:Q236	B:B:R314	4.67	No	Yes	2	8	8
135	A:A:C237	A:A:F238	2.79	No	Yes	2	8	9
136	A:A:C237	B:B:Y59	5.38	No	Yes	2	8	8
137	A:A:C237	B:B:W99	2.61	No	Yes	2	8	9
138	A:A:F238	A:A:V241	5.24	Yes	No	0	9	9
139	A:A:F238	B:B:W99	17.04	Yes	Yes	2	9	9
140	A:A:F238	B:B:L117	2.44	Yes	Yes	2	9	9
141	A:A:N239	A:A:W281	3.39	No	Yes	2	8	5
142	A:A:N239	B:B:K57	4.2	No	Yes	2	8	9
143	A:A:N239	B:B:W332	5.65	No	Yes	2	8	9
144	A:A:D240	B:B:K57	4.15	No	Yes	0	6	9
145	A:A:C379	A:A:T242	5.07	No	No	0	8	8
146	A:A:I383	A:A:T242	3.04	Yes	No	1	8	8
147	A:A:A243	A:A:I288	3.25	No	Yes	0	8	9
148	A:A:I244	A:A:I276	2.94	Yes	Yes	0	8	8
149	A:A:I244	A:A:L282	4.28	Yes	No	0	8	9
150	A:A:I244	A:A:I285	2.94	Yes	No	0	8	7
151	A:A:I245	A:A:I288	4.42	Yes	Yes	1	7	9
152	A:A:F290	A:A:I245	3.77	Yes	Yes	1	9	7
153	A:A:I245	A:A:I375	4.42	Yes	Yes	1	7	9
154	A:A:F246	A:A:V248	2.62	Yes	Yes	2	9	7
155	A:A:D272	A:A:F246	2.39	No	Yes	0	8	9
156	A:A:F246	A:A:F273	6.43	Yes	Yes	2	9	9
157	A:A:F246	A:A:I276	2.51	Yes	Yes	2	9	8
158	A:A:F246	A:A:L289	2.44	Yes	Yes	2	9	9
159	A:A:F290	A:A:V247	5.24	Yes	Yes	1	9	7
160	A:A:N292	A:A:V247	4.43	Yes	Yes	1	9	7
161	A:A:A269	A:A:V248	3.39	No	Yes	0	9	7
162	A:A:L291	A:A:V248	2.98	Yes	Yes	2	8	7
163	A:A:F345	A:A:V248	10.49	Yes	Yes	2	8	7
164	A:A:D249	A:A:S251	5.89	Yes	No	0	8	9
165	A:A:D249	A:A:D252	3.99	Yes	No	1	8	8
166	A:A:D249	A:A:K293	13.83	Yes	Yes	1	8	9
167	A:A:L291	A:A:S250	4.5	Yes	No	0	8	6
168	A:A:Q294	A:A:S250	2.89	Yes	No	0	6	6
169	A:A:I341	A:A:S250	4.64	No	No	0	8	6
170	A:A:L296	A:A:S251	6.01	No	No	0	6	9
171	A:A:D252	A:A:R265	9.53	No	Yes	1	8	9
172	A:A:L266	A:A:Y253	2.34	Yes	Yes	2	8	8
173	A:A:K300	A:A:Y253	11.94	Yes	Yes	2	9	8
174	A:A:I308	A:A:Y253	18.13	No	Yes	2	7	8
175	A:A:Y253	A:A:Y311	23.83	Yes	No	0	8	6
176	A:A:F312	A:A:Y253	15.47	Yes	Yes	2	8	8
177	A:A:N254	A:A:R265	4.82	No	Yes	0	9	9
178	A:A:E268	A:A:R265	2.33	No	Yes	0	9	9
179	A:A:L266	A:A:L270	2.77	Yes	Yes	2	8	6
180	A:A:F312	A:A:L266	4.87	Yes	Yes	2	8	8
181	A:A:I341	A:A:L266	4.28	No	Yes	0	8	8
182	A:A:L270	A:A:Q267	5.32	Yes	No	2	6	4
183	A:A:N271	A:A:Q267	6.6	No	No	0	5	4
184	A:A:F312	A:A:Q267	3.51	Yes	No	2	8	4
185	A:A:F312	A:A:L270	2.44	Yes	Yes	2	8	6
186	A:A:E344	A:A:L270	2.65	Yes	Yes	2	5	6
187	A:A:F345	A:A:L270	10.96	Yes	Yes	2	8	6
188	A:A:I348	A:A:L270	4.28	No	Yes	0	4	6
189	A:A:F273	A:A:W277	2	Yes	Yes	2	9	6
190	A:A:F273	A:A:V287	3.93	Yes	No	2	9	6
191	A:A:F273	A:A:L289	2.44	Yes	Yes	2	9	9
192	A:A:F273	A:A:F345	8.57	Yes	Yes	2	9	8
193	A:A:F273	A:A:I348	6.28	Yes	No	0	9	4
194	A:A:F273	A:A:S349	2.64	Yes	No	2	9	7
195	A:A:C359	A:A:F273	2.79	No	Yes	2	5	9
196	A:A:K274	A:A:N278	4.2	No	No	0	5	8
197	A:A:I348	A:A:K274	4.36	No	No	0	4	5
198	A:A:I276	A:A:S275	3.1	Yes	No	0	8	8
199	A:A:V287	A:A:W277	4.9	No	Yes	2	6	6
200	A:A:S349	A:A:W277	8.65	No	Yes	2	7	6
201	A:A:S352	A:A:W277	2.47	No	Yes	0	5	6
202	A:A:G353	A:A:W277	4.22	No	Yes	0	4	6
203	A:A:H357	A:A:W277	26.45	No	Yes	0	7	6
204	A:A:C359	A:A:W277	2.61	No	Yes	2	5	6
205	A:A:N278	A:A:S352	5.96	No	No	0	8	5
206	A:A:N279	A:A:R280	10.85	Yes	No	2	8	5
207	A:A:N279	A:A:W281	3.39	Yes	Yes	2	8	5
208	A:A:L282	A:A:N279	6.87	No	Yes	2	9	8
209	A:A:R280	A:A:W281	13	No	Yes	2	5	5
210	A:A:W281	B:B:R314	9	Yes	Yes	2	5	8
211	A:A:W281	B:B:W332	3.75	Yes	Yes	2	5	9
212	A:A:R356	A:A:T284	7.76	No	No	0	2	4
213	A:A:S286	A:A:Y360	5.09	No	Yes	1	8	8
214	A:A:I382	A:A:S286	7.74	Yes	No	1	6	8
215	A:A:F290	A:A:I288	3.77	Yes	Yes	1	9	9
216	A:A:H362	A:A:I288	2.65	No	Yes	1	9	9
217	A:A:D378	A:A:I288	11.2	Yes	Yes	1	7	9
218	A:A:L289	A:A:L291	6.92	Yes	Yes	2	9	8
219	A:A:F345	A:A:L289	8.53	Yes	Yes	2	8	9
220	A:A:L289	A:A:P361	3.28	Yes	No	2	9	5
221	A:A:F290	A:A:H362	6.79	Yes	No	1	9	9
222	A:A:F290	A:A:T364	5.19	Yes	Yes	1	9	9
223	A:A:F290	A:A:N371	4.83	Yes	Yes	1	9	9
224	A:A:F290	A:A:I375	5.02	Yes	Yes	1	9	9
225	A:A:L291	A:A:R342	2.43	Yes	Yes	2	8	4
226	A:A:F345	A:A:L291	2.44	Yes	Yes	2	8	8
227	A:A:F363	A:A:L291	6.09	Yes	Yes	2	5	8
228	A:A:K293	A:A:N292	4.2	Yes	Yes	1	9	9
229	A:A:N292	A:A:T364	5.85	Yes	Yes	1	9	9
230	A:A:N292	A:A:S366	5.96	Yes	No	1	9	9
231	A:A:K293	A:A:L296	4.23	Yes	No	0	9	6
232	A:A:K293	A:A:S366	4.59	Yes	No	1	9	9
233	A:A:L297	A:A:Q294	3.99	No	Yes	0	8	6
234	A:A:K338	A:A:Q294	8.14	No	Yes	2	5	6
235	A:A:F363	A:A:Q294	10.54	Yes	Yes	2	5	6
236	A:A:D295	A:A:L296	6.79	No	No	0	9	6
237	A:A:K300	A:A:L297	4.23	Yes	No	0	9	8
238	A:A:L297	A:A:V301	2.98	No	Yes	0	8	7
239	A:A:K300	A:A:S306	3.06	Yes	No	0	9	7
240	A:A:I308	A:A:K300	4.36	No	Yes	2	7	9
241	A:A:V301	A:A:V334	4.81	Yes	No	0	7	4
242	A:A:L302	A:A:R333	3.64	No	No	0	2	5
243	A:A:K305	A:A:S306	4.59	No	No	0	3	7
244	A:A:E309	A:A:K307	2.7	No	No	0	4	6
245	A:A:F315	A:A:I308	5.02	Yes	No	2	6	7
246	A:A:D310	A:A:Y311	10.34	No	No	0	3	6
247	A:A:F312	A:A:F340	7.5	Yes	Yes	2	8	7
248	A:A:E344	A:A:F312	3.5	Yes	Yes	2	5	8
249	A:A:F315	A:A:Y318	2.06	Yes	Yes	2	6	6
250	A:A:F315	A:A:R336	12.83	Yes	No	2	6	5
251	A:A:F315	A:A:F340	8.57	Yes	Yes	2	6	7
252	A:A:P321	A:A:Y318	5.56	No	Yes	2	5	6
253	A:A:R336	A:A:Y318	3.09	No	Yes	2	5	6
254	A:A:F340	A:A:Y318	9.28	Yes	Yes	2	7	6
255	A:A:D343	A:A:Y318	9.2	No	Yes	2	3	6
256	A:A:P321	A:A:T320	3.5	No	No	0	5	1
257	A:A:R336	A:A:T320	3.88	No	No	0	5	1
258	A:A:D343	A:A:P321	3.22	No	No	2	3	5
259	A:A:A324	A:A:Y339	9.34	No	Yes	0	3	3
260	A:A:P326	A:A:T335	10.49	No	No	0	1	4
261	A:A:E327	A:A:P328	14.15	No	No	0	4	1
262	A:A:G329	A:A:P328	2.03	No	No	8	7	1
263	A:A:E330	A:A:P328	4.72	No	No	8	3	1
264	A:A:E330	A:A:G329	3.27	No	No	8	3	7
265	A:A:E330	A:A:V334	2.85	No	No	0	3	4
266	A:A:D331	A:A:P332	3.22	No	No	0	4	1
267	A:A:D331	A:A:R333	5.96	No	No	0	4	5
268	A:A:T335	A:A:Y339	2.5	No	Yes	0	4	3
269	A:A:K338	A:A:Y339	7.17	No	Yes	2	5	3
270	A:A:F363	A:A:K338	9.93	Yes	No	2	5	5
271	A:A:R342	A:A:Y339	7.2	Yes	Yes	2	4	3
272	A:A:F363	A:A:Y339	8.25	Yes	Yes	2	5	3
273	A:A:E344	A:A:F340	15.16	Yes	Yes	2	5	7
274	A:A:F345	A:A:I341	2.51	Yes	No	0	8	8
275	A:A:D343	A:A:R342	5.96	No	Yes	2	3	4
276	A:A:L346	A:A:R342	8.5	No	Yes	2	4	4
277	A:A:P361	A:A:R342	5.76	No	Yes	2	5	4
278	A:A:F363	A:A:R342	6.41	Yes	Yes	2	5	4
279	A:A:E344	A:A:R347	6.98	Yes	No	0	5	4
280	A:A:L346	A:A:P361	3.28	No	No	2	4	5
281	A:A:C359	A:A:S349	6.89	No	No	2	5	7
282	A:A:R356	A:A:R389	6.4	No	No	0	2	4
283	A:A:Y358	A:A:Y360	13.9	No	Yes	1	4	8
284	A:A:Y358	R:R:V214	3.79	No	No	0	4	4
285	A:A:Y358	R:R:S215	5.09	No	Yes	1	4	4
286	A:A:D378	A:A:Y360	14.94	Yes	Yes	1	7	8
287	A:A:D381	A:A:Y360	10.34	Yes	Yes	1	8	8
288	A:A:I382	A:A:Y360	9.67	Yes	Yes	1	6	8
289	A:A:Y360	R:R:S215	3.82	Yes	Yes	1	8	4
290	A:A:H362	A:A:R374	18.05	No	Yes	1	9	4
291	A:A:D368	A:A:T364	5.78	No	Yes	1	9	9
292	A:A:N371	A:A:T364	7.31	Yes	Yes	1	9	9
293	A:A:R374	A:A:T364	2.59	Yes	Yes	1	4	9
294	A:A:C365	A:A:D368	6.22	No	No	0	8	9
295	A:A:D368	A:A:N371	2.69	No	Yes	1	9	9
296	A:A:E370	A:A:T369	5.64	No	No	0	4	9
297	A:A:E370	A:A:R374	6.98	No	Yes	0	4	4
298	A:A:N371	A:A:R374	4.82	Yes	Yes	1	9	4
299	A:A:F376	A:A:R373	2.14	Yes	Yes	1	8	5
300	A:A:N377	A:A:R373	2.41	No	Yes	1	4	5
301	A:A:F376	A:A:N377	2.42	Yes	No	1	8	4
302	A:A:F376	R:R:L125	3.65	Yes	Yes	1	8	5
303	A:A:C379	A:A:D378	3.11	No	Yes	0	8	7
304	A:A:D378	A:A:I382	8.4	Yes	Yes	1	7	6
305	A:A:R380	R:R:P124	7.21	No	Yes	0	7	8
306	A:A:R380	R:R:L125	4.86	No	Yes	0	7	5
307	A:A:D381	R:R:S213	4.42	Yes	No	0	8	6
308	A:A:D381	R:R:V214	4.38	Yes	No	0	8	4
309	A:A:D381	R:R:S215	4.42	Yes	Yes	1	8	4
310	A:A:H387	A:A:I383	6.63	Yes	Yes	1	8	8
311	A:A:I383	R:R:P124	3.39	Yes	Yes	1	8	8
312	A:A:I383	R:R:L125	4.28	Yes	Yes	1	8	5
313	A:A:Q384	R:R:V121	2.87	No	No	0	6	8
314	A:A:Q384	R:R:P124	4.74	No	Yes	0	6	8
315	A:A:Q384	R:R:S213	2.89	No	No	0	6	6
316	A:A:L394	A:A:R385	2.43	Yes	Yes	1	8	5
317	A:A:R385	R:R:S215	5.27	Yes	Yes	1	5	4
318	A:A:R385	R:R:T216	5.17	Yes	Yes	1	5	3
319	A:A:R385	R:R:E220	9.3	Yes	No	1	5	5
320	A:A:H387	A:A:Q390	4.95	Yes	No	1	8	4
321	A:A:H387	A:A:Y391	5.44	Yes	Yes	1	8	4
322	A:A:H387	R:R:A120	5.85	Yes	No	1	8	7
323	A:A:H387	R:R:P124	3.05	Yes	Yes	1	8	8
324	A:A:H387	R:R:R131	10.16	Yes	Yes	1	8	7
325	A:A:L388	A:A:L394	5.54	Yes	Yes	1	8	8
326	A:A:L388	R:R:V121	5.96	Yes	No	0	8	8
327	A:A:L388	R:R:V210	4.47	Yes	No	1	8	8
328	A:A:L388	R:R:I224	2.85	Yes	No	1	8	6
329	A:A:L394	A:A:R389	2.43	Yes	No	0	8	4
330	A:A:Q390	A:A:Y391	10.15	No	Yes	1	4	4
331	A:A:Q390	R:R:N52	2.64	No	No	0	4	7
332	A:A:Y391	R:R:E53	5.61	Yes	Yes	1	4	6
333	A:A:Y391	R:R:L54	7.03	Yes	Yes	1	4	7
334	A:A:Y391	R:R:D116	5.75	Yes	Yes	1	4	8
335	A:A:Y391	R:R:R117	2.06	Yes	Yes	1	4	9
336	A:A:Y391	R:R:A120	9.34	Yes	No	1	4	7
337	A:A:Y391	R:R:R131	7.2	Yes	Yes	1	4	7
338	A:A:E392	R:R:Q47	5.1	No	No	0	6	5
339	A:A:E392	R:R:R117	2.33	No	Yes	0	6	9
340	A:A:E392	R:R:N292	15.77	No	No	0	6	8
341	A:A:L393	R:R:R117	7.29	No	Yes	0	8	9
342	A:A:L394	R:R:E220	6.63	Yes	No	1	8	5
343	A:A:L394	R:R:I224	5.71	Yes	No	1	8	6
344	B:B:E3	B:B:L4	7.95	No	No	0	5	4
345	B:B:D5	B:B:E3	12.99	No	No	0	1	5
346	B:B:D5	B:B:R8	7.15	No	No	0	1	3
347	B:B:L7	G:G:R13	6.07	No	No	0	8	6
348	B:B:E10	G:G:V16	5.7	No	Yes	0	8	7
349	B:B:L14	G:G:L19	4.15	No	Yes	0	8	9
350	B:B:K15	G:G:L19	7.05	No	Yes	0	6	9
351	B:B:I18	B:B:Q17	2.74	Yes	No	0	7	4
352	B:B:I18	B:B:R22	5.01	Yes	Yes	4	7	6
353	B:B:I18	G:G:L19	2.85	Yes	Yes	4	7	9
354	B:B:I18	G:G:E22	4.1	Yes	Yes	4	7	9
355	B:B:I18	G:G:A23	3.25	Yes	No	0	7	8
356	B:B:D258	B:B:R22	13.1	Yes	Yes	4	7	6
357	B:B:Q259	B:B:R22	3.5	Yes	Yes	0	6	6
358	B:B:R22	G:G:R27	2.13	Yes	Yes	4	6	8
359	B:B:C25	B:B:Q259	3.05	No	Yes	0	3	6
360	B:B:C25	G:G:R27	4.18	No	Yes	0	3	8
361	B:B:A26	B:B:Q259	4.55	No	Yes	0	3	6
362	B:B:D27	G:G:K29	11.06	No	No	9	8	4
363	B:B:D27	G:G:S31	8.83	No	Yes	9	8	9
364	B:B:Q32	B:B:T29	7.09	No	No	0	1	3
365	B:B:L30	B:B:T34	4.42	Yes	No	0	5	5
366	B:B:L261	B:B:L30	2.77	No	Yes	0	5	5
367	B:B:L30	B:B:M262	7.07	Yes	Yes	0	5	4
368	B:B:L30	G:G:A34	3.15	Yes	No	0	5	6
369	B:B:I37	B:B:T34	4.56	Yes	No	2	2	5
370	B:B:L300	B:B:T34	4.42	Yes	No	2	6	5
371	B:B:N35	B:B:N36	2.72	No	No	0	1	1
372	B:B:I37	B:B:N36	4.25	Yes	No	0	2	1
373	B:B:I37	B:B:R283	5.01	Yes	Yes	2	2	9
374	B:B:I37	B:B:L300	2.85	Yes	Yes	2	2	6
375	B:B:I37	G:G:M38	4.37	Yes	No	0	2	4
376	B:B:D38	B:B:P39	3.22	No	No	0	1	1
377	B:B:D298	B:B:V40	8.76	Yes	No	0	9	3
378	B:B:A305	B:B:V40	3.39	No	No	0	4	3
379	B:B:Q44	B:B:R42	3.5	No	No	0	4	2
380	B:B:I43	B:B:L284	2.85	No	No	10	3	5
381	B:B:I43	B:B:V296	6.14	No	No	10	3	5
382	B:B:A305	B:B:I43	3.25	No	No	0	4	3
383	B:B:L308	B:B:M45	4.24	No	No	7	7	4
384	B:B:M45	B:B:W339	2.33	No	Yes	7	4	9
385	B:B:M45	G:G:L50	7.07	No	No	0	4	9
386	B:B:R46	B:B:R48	3.2	No	No	0	5	7
387	B:B:K337	B:B:T47	7.51	Yes	No	7	6	3
388	B:B:T47	B:B:W339	6.06	No	Yes	7	3	9
389	B:B:R48	B:B:R49	2.13	No	Yes	3	7	7
390	B:B:R48	G:G:F61	3.21	No	Yes	3	7	8
391	B:B:R49	B:B:T87	5.17	Yes	No	0	7	5
392	B:B:I338	B:B:R49	2.51	Yes	Yes	3	5	7
393	B:B:R49	G:G:F61	8.55	Yes	Yes	3	7	8
394	B:B:R52	B:B:T50	6.47	No	No	0	7	3
395	B:B:K337	B:B:T50	9.01	Yes	No	0	6	3
396	B:B:L51	B:B:W82	20.5	Yes	Yes	3	9	9
397	B:B:L51	B:B:T87	2.95	Yes	No	0	9	5
398	B:B:L336	B:B:L51	8.3	Yes	Yes	3	7	9
399	B:B:I338	B:B:L51	2.85	Yes	Yes	3	5	9
400	B:B:F335	B:B:R52	8.55	Yes	No	0	4	7
401	B:B:H54	B:B:I58	7.95	Yes	Yes	3	9	9
402	B:B:H54	B:B:S72	8.37	Yes	Yes	3	9	9
403	B:B:H54	B:B:S74	15.34	Yes	No	3	9	9
404	B:B:D76	B:B:H54	2.52	Yes	Yes	3	9	9
405	B:B:H54	B:B:I80	13.26	Yes	No	3	9	8
406	B:B:H54	B:B:W82	2.12	Yes	Yes	3	9	9
407	B:B:D76	B:B:L55	9.5	Yes	No	0	9	6
408	B:B:K57	B:B:Y59	5.97	Yes	Yes	2	9	8
409	B:B:K57	B:B:Q75	4.07	Yes	No	2	9	9
410	B:B:K57	B:B:W332	26.69	Yes	Yes	2	9	9
411	B:B:I58	B:B:S72	4.64	Yes	Yes	3	9	9
412	B:B:I58	B:B:S316	3.1	Yes	No	0	9	9
413	B:B:I58	B:B:L336	2.85	Yes	Yes	3	9	7
414	B:B:Q75	B:B:Y59	13.53	No	Yes	2	9	8
415	B:B:W332	B:B:Y59	13.5	Yes	Yes	2	9	8
416	B:B:A60	B:B:C103	3.61	No	No	0	7	8
417	B:B:M61	B:B:W63	2.33	Yes	Yes	3	6	7
418	B:B:L70	B:B:M61	5.65	Yes	Yes	3	5	6
419	B:B:C317	B:B:M61	4.86	No	Yes	0	7	6
420	B:B:A328	B:B:M61	3.22	No	Yes	3	5	6
421	B:B:L336	B:B:M61	2.83	Yes	Yes	3	7	6
422	B:B:A104	B:B:H62	2.93	No	No	0	7	6
423	B:B:H62	B:B:R150	20.31	No	Yes	0	6	6
424	B:B:L70	B:B:W63	10.25	Yes	Yes	3	5	7
425	B:B:S84	B:B:W63	4.94	Yes	Yes	3	5	7
426	B:B:G319	B:B:W63	2.81	No	Yes	0	5	7
427	B:B:T321	B:B:W63	10.92	No	Yes	3	7	7
428	B:B:A328	B:B:W63	5.19	No	Yes	3	5	7
429	B:B:I338	B:B:W63	4.7	Yes	Yes	3	5	7
430	B:B:G64	B:B:Y105	4.35	No	Yes	0	5	6
431	B:B:D322	B:B:T65	4.34	No	No	0	1	1
432	B:B:D66	B:B:R68	2.38	No	No	0	8	5
433	B:B:D66	B:B:L69	9.5	No	No	0	8	5
434	B:B:S67	B:B:T321	6.4	No	No	3	5	7
435	B:B:D323	B:B:S67	11.78	No	No	3	7	5
436	B:B:D83	B:B:R68	13.1	No	No	0	8	5
437	B:B:R68	B:B:Y85	28.81	No	Yes	0	5	4
438	B:B:L69	B:B:Y105	4.69	No	Yes	0	5	6
439	B:B:L70	B:B:W82	2.28	Yes	Yes	3	5	9
440	B:B:A328	B:B:L70	3.15	No	Yes	3	5	5
441	B:B:L79	B:B:V71	2.98	Yes	No	0	7	8
442	B:B:C103	B:B:V71	3.42	No	No	0	8	8
443	B:B:V112	B:B:V71	4.81	Yes	No	0	8	8
444	B:B:S72	B:B:W82	2.47	Yes	Yes	3	9	9
445	B:B:L336	B:B:S72	6.01	Yes	Yes	3	7	9
446	B:B:A73	B:B:V100	3.39	No	No	0	9	9
447	B:B:A73	B:B:C103	3.61	No	No	0	9	8
448	B:B:D76	B:B:S74	10.31	Yes	No	3	9	9
449	B:B:Q75	B:B:W99	5.48	No	Yes	2	9	9
450	B:B:D76	B:B:K78	8.3	Yes	Yes	0	9	8
451	B:B:K78	B:B:P94	3.35	Yes	No	0	8	5
452	B:B:I93	B:B:L79	5.71	Yes	Yes	6	7	7
453	B:B:L79	B:B:L95	6.92	Yes	Yes	6	7	8
454	B:B:C114	B:B:L79	7.94	Yes	Yes	6	8	7
455	B:B:L79	B:B:Y124	2.34	Yes	Yes	6	7	6
456	B:B:I80	B:B:W82	12.92	No	Yes	3	8	9
457	B:B:I81	B:B:V90	4.61	No	No	6	7	5
458	B:B:H91	B:B:I81	10.61	Yes	No	6	5	7
459	B:B:I81	B:B:L126	4.28	No	Yes	6	7	5
460	B:B:K89	B:B:W82	9.28	Yes	Yes	3	9	9
461	B:B:L336	B:B:W82	3.42	Yes	Yes	3	7	9
462	B:B:D83	B:B:T86	8.67	No	No	3	8	6
463	B:B:D83	B:B:N88	2.69	No	Yes	3	8	7
464	B:B:S84	B:B:Y85	2.54	Yes	Yes	3	5	4
465	B:B:I338	B:B:S84	6.19	Yes	Yes	3	5	5
466	B:B:S84	G:G:F61	7.93	Yes	Yes	3	5	8
467	B:B:Y85	G:G:P60	15.3	Yes	No	0	4	9
468	B:B:Y85	G:G:F61	7.22	Yes	Yes	3	4	8
469	B:B:N88	B:B:T86	10.24	Yes	No	3	7	6
470	B:B:H91	B:B:V90	8.3	Yes	No	6	5	5
471	B:B:H91	B:B:V133	5.54	Yes	Yes	6	5	4
472	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
473	B:B:I93	B:B:Y124	4.84	Yes	Yes	6	7	6
474	B:B:I93	B:B:V133	4.61	Yes	Yes	6	7	4
475	B:B:L95	B:B:V100	4.47	Yes	No	0	8	9
476	B:B:C114	B:B:L95	4.76	Yes	Yes	6	8	8
477	B:B:L95	B:B:Y124	7.03	Yes	Yes	6	8	6
478	B:B:D118	B:B:S97	10.31	No	No	0	9	8
479	B:B:S98	B:B:W99	8.65	No	Yes	2	8	9
480	B:B:L117	B:B:W99	4.56	Yes	Yes	2	9	9
481	B:B:L117	B:B:M101	2.83	Yes	No	2	9	9
482	B:B:M101	B:B:Y145	4.79	No	Yes	2	9	8
483	B:B:C148	B:B:T102	3.38	No	No	0	6	8
484	B:B:C149	B:B:T102	3.38	No	No	0	8	8
485	B:B:G109	B:B:Y105	5.79	No	Yes	0	5	6
486	B:B:V112	B:B:Y105	3.79	Yes	Yes	6	8	6
487	B:B:L126	B:B:Y105	2.34	Yes	Yes	6	5	6
488	B:B:A106	B:B:F151	5.55	No	Yes	0	6	9
489	B:B:F151	B:B:P107	2.89	Yes	No	0	9	6
490	B:B:G109	B:B:S108	3.71	No	No	0	5	6
491	B:B:N110	B:B:S108	8.94	Yes	No	2	4	6
492	B:B:D154	B:B:S108	8.83	No	No	2	6	6
493	B:B:N110	B:B:Y111	3.49	Yes	Yes	2	4	4
494	B:B:K127	B:B:N110	8.39	No	Yes	0	4	4
495	B:B:D154	B:B:N110	4.04	No	Yes	2	6	4
496	B:B:I123	B:B:Y111	3.63	Yes	Yes	2	6	4
497	B:B:N125	B:B:Y111	11.63	No	Yes	0	4	4
498	B:B:S136	B:B:Y111	3.82	No	Yes	0	4	4
499	B:B:F151	B:B:Y111	2.06	Yes	Yes	2	9	4
500	B:B:D154	B:B:Y111	6.9	No	Yes	2	6	4
501	B:B:V112	B:B:Y124	3.79	Yes	Yes	6	8	6
502	B:B:L126	B:B:V112	5.96	Yes	Yes	6	5	8
503	B:B:A113	B:B:F151	4.16	No	Yes	0	9	9
504	B:B:C114	B:B:G115	1.96	Yes	No	0	8	9
505	B:B:C114	B:B:Y124	5.38	Yes	Yes	6	8	6
506	B:B:G115	B:B:G116	2.11	No	No	0	9	9
507	B:B:L117	B:B:Y145	3.52	Yes	Yes	2	9	8
508	B:B:D118	B:B:I120	4.2	No	No	0	9	6
509	B:B:G144	B:B:N119	5.09	No	No	0	8	9
510	B:B:E138	B:B:I120	4.1	No	No	0	6	6
511	B:B:C121	B:B:C149	3.64	No	No	0	8	8
512	B:B:C121	B:B:T159	3.38	No	No	0	8	9
513	B:B:S122	B:B:Y124	6.36	No	Yes	0	8	6
514	B:B:E138	B:B:S122	7.19	No	No	0	6	8
515	B:B:I123	B:B:L139	2.85	Yes	Yes	0	6	9
516	B:B:F151	B:B:I123	2.51	Yes	Yes	2	9	6
517	B:B:I123	B:B:I171	4.42	Yes	No	2	6	6
518	B:B:V133	B:B:Y124	2.52	Yes	Yes	6	4	6
519	B:B:V135	B:B:Y124	6.31	No	Yes	0	4	6
520	B:B:N125	B:B:T128	5.85	No	No	0	4	3
521	B:B:L126	B:B:V133	4.47	Yes	Yes	6	5	4
522	B:B:R134	B:B:T128	5.17	No	No	0	3	3
523	B:B:E130	B:B:R129	6.98	Yes	No	0	3	3
524	B:B:E130	B:B:N132	7.89	Yes	No	11	3	3
525	B:B:E130	B:B:R134	2.33	Yes	No	11	3	3
526	B:B:N132	B:B:R134	4.82	No	No	11	3	3
527	B:B:E138	B:B:V135	4.28	No	No	0	6	4
528	B:B:L139	B:B:R137	2.43	Yes	No	0	9	5
529	B:B:L139	B:B:W169	18.22	Yes	Yes	0	9	8
530	B:B:H142	B:B:L146	7.71	Yes	No	2	9	7
531	B:B:H142	B:B:T159	6.85	Yes	No	2	9	9
532	B:B:H142	B:B:S161	15.34	Yes	Yes	2	9	9
533	B:B:D163	B:B:H142	7.56	Yes	Yes	2	9	9
534	B:B:H142	B:B:T165	2.74	Yes	No	2	9	7
535	B:B:A167	B:B:H142	2.93	No	Yes	2	4	9
536	B:B:H142	B:B:W169	3.17	Yes	Yes	2	9	8
537	B:B:D163	B:B:T143	5.78	Yes	No	0	9	5
538	B:B:S147	B:B:Y145	2.54	No	Yes	0	9	8
539	B:B:G162	B:B:Y145	7.24	No	Yes	2	9	8
540	B:B:D186	B:B:Y145	8.05	Yes	Yes	2	9	8
541	B:B:M188	B:B:Y145	3.59	No	Yes	2	8	8
542	B:B:L146	B:B:S161	3	No	Yes	2	7	9
543	B:B:S147	B:B:S160	4.89	No	No	0	9	6
544	B:B:C148	B:B:R150	2.79	No	Yes	5	6	6
545	B:B:C148	B:B:L190	3.17	No	Yes	5	6	5
546	B:B:C149	B:B:I157	3.27	No	Yes	0	8	7
547	B:B:L190	B:B:R150	2.43	Yes	Yes	5	5	6
548	B:B:L192	B:B:R150	3.64	No	Yes	0	5	6
549	B:B:F151	B:B:I157	12.56	Yes	Yes	2	9	7
550	B:B:F151	B:B:I171	3.77	Yes	No	2	9	6
551	B:B:L152	B:B:Q156	6.65	Yes	No	0	3	5
552	B:B:L152	B:B:V158	2.98	Yes	No	0	3	5
553	B:B:L152	B:B:L192	5.54	Yes	No	0	3	5
554	B:B:L152	B:B:T196	4.42	Yes	No	0	3	1
555	B:B:D153	B:B:Q156	9.14	No	No	0	5	5
556	B:B:D170	B:B:N155	9.42	No	No	0	9	3
557	B:B:E172	B:B:N155	21.03	No	No	0	6	3
558	B:B:L168	B:B:Q156	2.66	Yes	No	0	6	5
559	B:B:I157	B:B:W169	3.52	Yes	Yes	2	7	8
560	B:B:I157	B:B:I171	2.94	Yes	No	2	7	6
561	B:B:L190	B:B:V158	7.45	Yes	No	5	5	5
562	B:B:F199	B:B:V158	6.55	Yes	No	5	9	5
563	B:B:T159	B:B:W169	9.7	No	Yes	2	9	8
564	B:B:S160	B:B:V187	4.85	No	Yes	0	6	9
565	B:B:L190	B:B:S160	6.01	Yes	No	0	5	6
566	B:B:G162	B:B:S161	3.71	No	Yes	2	9	9
567	B:B:D163	B:B:S161	10.31	Yes	Yes	2	9	9
568	B:B:D186	B:B:G162	5.03	Yes	No	2	9	9
569	B:B:D163	B:B:T165	10.12	Yes	No	2	9	7
570	B:B:T165	B:B:T181	3.14	No	No	0	7	2
571	B:B:C166	B:B:F180	2.79	Yes	Yes	5	8	7
572	B:B:C166	B:B:V187	5.12	Yes	Yes	5	8	9
573	B:B:C166	B:B:F199	4.19	Yes	Yes	5	8	9
574	B:B:C166	B:B:S201	3.44	Yes	No	5	8	9
575	B:B:A167	B:B:W169	5.19	No	Yes	2	4	8
576	B:B:A167	B:B:Q176	6.06	No	Yes	2	4	4
577	B:B:L168	B:B:T178	4.42	Yes	No	5	6	4
578	B:B:F180	B:B:L168	2.44	Yes	Yes	5	7	6
579	B:B:L168	B:B:V213	4.47	Yes	No	0	6	4
580	B:B:Q176	B:B:W169	13.14	Yes	Yes	2	4	8
581	B:B:D170	B:B:T173	5.78	No	No	0	9	5
582	B:B:Q175	B:B:T173	11.34	No	No	0	4	5
583	B:B:Q176	B:B:T179	7.09	Yes	No	0	4	4
584	B:B:T177	B:B:T178	3.14	No	No	0	4	4
585	B:B:F180	B:B:T178	6.49	Yes	No	5	7	4
586	B:B:F180	B:B:F199	8.57	Yes	Yes	5	7	9
587	B:B:F180	B:B:W211	14.03	Yes	Yes	5	7	8
588	B:B:F180	B:B:G216	4.52	Yes	No	0	7	4
589	B:B:H183	B:B:V187	5.54	Yes	Yes	5	9	9
590	B:B:H183	B:B:S201	5.58	Yes	No	5	9	9
591	B:B:A203	B:B:H183	8.78	No	Yes	5	8	9
592	B:B:D205	B:B:H183	10.08	Yes	Yes	5	9	9
593	B:B:H183	B:B:S207	2.79	Yes	Yes	5	9	5
594	B:B:H183	B:B:K209	14.41	Yes	Yes	5	9	6
595	B:B:H183	B:B:W211	2.12	Yes	Yes	5	9	8
596	B:B:D205	B:B:T184	5.78	Yes	No	0	9	3
597	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
598	B:B:D186	B:B:M188	4.16	Yes	No	2	9	8
599	B:B:C204	B:B:D186	3.11	Yes	Yes	2	7	9
600	B:B:A203	B:B:V187	3.39	No	Yes	5	8	9
601	B:B:I232	B:B:S189	6.19	Yes	No	0	8	7
602	B:B:F199	B:B:L190	6.09	Yes	Yes	5	9	5
603	B:B:F234	B:B:S191	6.61	Yes	No	0	5	8
604	B:B:F199	B:B:L192	3.65	Yes	No	0	9	5
605	B:B:A193	B:B:D195	3.09	No	No	0	4	5
606	B:B:A193	B:B:F234	5.55	No	Yes	0	4	5
607	B:B:G238	B:B:P194	4.06	No	No	0	7	4
608	B:B:D195	B:B:R197	7.15	No	No	0	5	5
609	B:B:L198	B:B:L210	9.69	No	Yes	0	3	5
610	B:B:D212	B:B:L198	4.07	Yes	No	0	9	3
611	B:B:F199	B:B:W211	11.02	Yes	Yes	5	9	8
612	B:B:L210	B:B:V200	5.96	Yes	Yes	4	5	6
613	B:B:I232	B:B:V200	7.68	Yes	Yes	4	8	6
614	B:B:F234	B:B:V200	10.49	Yes	Yes	4	5	6
615	B:B:F241	B:B:V200	6.55	Yes	Yes	4	6	6
616	B:B:S201	B:B:W211	7.41	No	Yes	5	9	8
617	B:B:G202	B:B:I229	3.53	No	No	0	6	7
618	B:B:A203	B:B:D205	4.63	No	Yes	5	8	9
619	B:B:C204	B:B:D228	6.22	Yes	Yes	2	7	9
620	B:B:D205	B:B:S207	10.31	Yes	Yes	5	9	5
621	B:B:S207	B:B:T221	3.2	Yes	No	0	5	7
622	B:B:A208	B:B:F241	2.77	No	Yes	0	6	6
623	B:B:K209	B:B:W211	8.12	Yes	Yes	5	6	8
624	B:B:C218	B:B:K209	6.47	No	Yes	5	5	6
625	B:B:K209	B:B:T221	13.51	Yes	No	0	6	7
626	B:B:F234	B:B:L210	2.44	Yes	Yes	4	5	5
627	B:B:L210	B:B:L255	5.54	Yes	Yes	4	5	6
628	B:B:C218	B:B:W211	5.22	No	Yes	5	5	8
629	B:B:D212	B:B:E215	19.49	Yes	No	12	9	3
630	B:B:D212	B:B:R219	11.91	Yes	No	12	9	5
631	B:B:E215	B:B:R219	4.65	No	No	12	3	5
632	B:B:M217	B:B:R219	8.69	No	No	0	3	5
633	B:B:M217	G:G:M21	2.89	No	No	0	3	1
634	B:B:C218	G:G:Q18	3.05	No	No	0	5	9
635	B:B:F222	B:B:Q220	7.03	Yes	Yes	4	8	7
636	B:B:L255	B:B:Q220	2.66	Yes	Yes	4	6	7
637	B:B:D258	B:B:Q220	16.97	Yes	Yes	4	7	7
638	B:B:Q220	G:G:I25	5.49	Yes	Yes	4	7	2
639	B:B:T221	G:G:E22	4.23	No	Yes	0	7	9
640	B:B:F222	B:B:F241	9.65	Yes	Yes	4	8	6
641	B:B:F222	B:B:F253	10.72	Yes	Yes	4	8	6
642	B:B:F222	B:B:L255	2.44	Yes	Yes	4	8	6
643	B:B:D258	B:B:F222	4.78	Yes	Yes	4	7	8
644	B:B:G224	B:B:R251	3	No	Yes	4	6	8
645	B:B:F253	B:B:G224	3.01	Yes	No	4	6	6
646	B:B:H225	B:B:I229	11.93	Yes	No	4	9	7
647	B:B:H225	B:B:T243	10.95	Yes	Yes	4	9	8
648	B:B:H225	B:B:S245	16.74	Yes	No	4	9	9
649	B:B:D247	B:B:H225	3.78	Yes	Yes	4	9	9
650	B:B:H225	B:B:R251	18.05	Yes	Yes	4	9	8
651	B:B:D247	B:B:E226	7.8	Yes	No	0	9	3
652	B:B:E226	B:B:R251	4.65	No	Yes	0	3	8
653	B:B:D228	B:B:S227	7.36	Yes	No	2	9	6
654	B:B:D246	B:B:S227	2.94	Yes	No	2	9	6
655	B:B:D228	B:B:D246	11.98	Yes	Yes	2	9	9
656	B:B:I229	B:B:T243	6.08	No	Yes	4	7	8
657	B:B:D246	B:B:N230	12.12	Yes	No	2	9	9
658	B:B:A231	B:B:V276	3.39	No	No	0	5	6
659	B:B:F241	B:B:I232	5.02	Yes	Yes	4	6	8
660	B:B:I232	B:B:T243	3.04	Yes	Yes	4	8	8
661	B:B:C233	B:B:F278	4.19	No	Yes	0	3	7
662	B:B:F235	B:B:P236	14.45	Yes	Yes	2	6	7
663	B:B:F235	B:B:N237	2.42	Yes	No	2	6	5
664	B:B:A240	B:B:F235	2.77	No	Yes	2	6	6
665	B:B:F235	B:B:F278	10.72	Yes	Yes	2	6	7
666	B:B:F235	B:B:G282	4.52	Yes	No	2	6	9
667	B:B:F235	G:G:L37	7.31	Yes	No	2	6	7
668	B:B:F235	G:G:Y40	5.16	Yes	Yes	2	6	6
669	B:B:F235	G:G:C41	2.79	Yes	No	2	6	7
670	B:B:F278	B:B:P236	2.89	Yes	Yes	2	7	7
671	B:B:G282	B:B:P236	4.06	No	Yes	2	9	7
672	B:B:P236	G:G:Y40	9.74	Yes	Yes	2	7	6
673	B:B:N237	B:B:N239	12.26	No	No	0	5	2
674	B:B:N237	G:G:Y40	4.65	No	Yes	2	5	6
675	B:B:N239	B:B:R256	7.23	No	Yes	0	2	9
676	B:B:A240	G:G:L37	3.15	No	No	2	6	7
677	B:B:F241	B:B:T243	2.59	Yes	Yes	4	6	8
678	B:B:F241	B:B:F253	13.93	Yes	Yes	4	6	6
679	B:B:F241	B:B:L255	2.44	Yes	Yes	4	6	6
680	B:B:A242	B:B:F278	2.77	No	Yes	2	4	7
681	B:B:A242	B:B:L285	3.15	No	Yes	2	4	6
682	B:B:F253	B:B:T243	7.78	Yes	Yes	4	6	8
683	B:B:C250	B:B:G244	1.96	No	No	2	8	5
684	B:B:G244	B:B:I273	7.05	No	Yes	2	5	6
685	B:B:D247	B:B:S245	8.83	Yes	No	4	9	9
686	B:B:D247	B:B:T249	7.23	Yes	Yes	4	9	6
687	B:B:R251	B:B:T249	5.17	Yes	Yes	4	8	6
688	B:B:T249	B:B:T263	3.14	Yes	No	4	6	1
689	B:B:C250	B:B:Y264	5.38	No	Yes	2	8	5
690	B:B:C250	B:B:I273	3.27	No	Yes	2	8	6
691	B:B:F253	B:B:R251	3.21	Yes	Yes	4	6	8
692	B:B:E260	B:B:R251	22.1	No	Yes	4	6	8
693	B:B:R251	B:B:T263	5.17	Yes	No	4	8	1
694	B:B:L252	B:B:Y264	5.86	No	Yes	0	7	5
695	B:B:F278	B:B:L252	2.44	Yes	No	0	7	7
696	B:B:E260	B:B:F253	4.66	No	Yes	4	6	6
697	B:B:D254	B:B:R256	3.57	Yes	Yes	0	9	9
698	B:B:A257	B:B:D254	3.09	No	Yes	0	7	9
699	B:B:D254	B:B:L261	5.43	Yes	No	0	9	5
700	B:B:D254	G:G:A33	6.18	Yes	No	0	9	7
701	B:B:D254	G:G:L37	2.71	Yes	No	0	9	7
702	B:B:R256	G:G:I28	8.77	Yes	No	0	9	4
703	B:B:R256	G:G:D36	8.34	Yes	No	0	9	5
704	B:B:D258	G:G:I25	2.8	Yes	Yes	4	7	2
705	B:B:D258	G:G:R27	8.34	Yes	Yes	4	7	8
706	B:B:Q259	G:G:V30	4.3	Yes	No	0	6	8
707	B:B:E260	B:B:T263	2.82	No	No	4	6	1
708	B:B:M262	B:B:Y264	8.38	Yes	Yes	2	4	5
709	B:B:A302	B:B:M262	3.22	No	Yes	2	2	4
710	B:B:L285	B:B:Y264	4.69	Yes	Yes	2	6	5
711	B:B:W297	B:B:Y264	13.5	Yes	Yes	2	8	5
712	B:B:A302	B:B:Y264	2.67	No	Yes	2	2	5
713	B:B:D267	B:B:H266	7.56	No	Yes	2	3	4
714	B:B:H266	B:B:N268	24.23	Yes	Yes	2	4	4
715	B:B:H266	B:B:I269	5.3	Yes	Yes	2	4	4
716	B:B:H266	B:B:R304	13.54	Yes	Yes	2	4	5
717	B:B:D267	B:B:N268	6.73	No	Yes	2	3	4
718	B:B:I269	B:B:N268	4.25	Yes	Yes	2	4	4
719	B:B:N268	B:B:R304	7.23	Yes	Yes	2	4	5
720	B:B:I269	B:B:Y289	4.84	Yes	Yes	2	4	7
721	B:B:I269	B:B:W297	2.35	Yes	Yes	2	4	8
722	B:B:C271	B:B:Y289	2.69	No	Yes	2	5	7
723	B:B:C271	B:B:D290	3.11	No	Yes	2	5	6
724	B:B:C271	B:B:D291	6.22	No	No	2	5	8
725	B:B:I273	B:B:V276	4.61	Yes	No	0	6	6
726	B:B:A287	B:B:I273	3.25	No	Yes	2	6	6
727	B:B:S275	B:B:T274	3.2	No	No	0	8	8
728	B:B:D290	B:B:T274	4.34	Yes	No	2	6	8
729	B:B:R314	B:B:T274	5.17	Yes	No	2	8	8
730	B:B:L318	B:B:S275	6.01	No	No	0	6	8
731	B:B:L285	B:B:V276	2.98	Yes	No	0	6	6
732	B:B:S277	B:B:V320	4.85	No	No	0	5	7
733	B:B:F278	B:B:L285	9.74	Yes	Yes	2	7	6
734	B:B:S279	G:G:D48	8.83	No	Yes	0	9	9
735	B:B:S279	G:G:L50	4.5	No	No	0	9	9
736	B:B:G324	B:B:K280	5.23	No	No	0	9	1
737	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
738	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
739	B:B:G282	G:G:C41	1.96	No	No	2	9	7
740	B:B:D298	B:B:R283	15.48	Yes	Yes	2	9	9
741	B:B:L300	B:B:R283	7.29	Yes	Yes	2	6	9
742	B:B:R283	G:G:L51	6.07	Yes	Yes	0	9	6
743	B:B:L284	B:B:V296	5.96	No	No	10	5	5
744	B:B:L284	G:G:L51	2.77	No	Yes	0	5	6
745	B:B:L286	B:B:V296	4.47	No	No	0	7	5
746	B:B:L286	B:B:V327	4.47	No	No	0	7	6
747	B:B:A287	B:B:Y289	4	No	Yes	2	6	7
748	B:B:A287	B:B:W297	2.59	No	Yes	2	6	8
749	B:B:C294	B:B:G288	3.92	No	No	0	5	7
750	B:B:D291	B:B:Y289	4.6	No	Yes	2	8	7
751	B:B:N295	B:B:Y289	10.47	Yes	Yes	2	6	7
752	B:B:W297	B:B:Y289	7.72	Yes	Yes	2	8	7
753	B:B:D290	B:B:R314	14.29	Yes	Yes	2	6	8
754	B:B:F292	B:B:N313	4.83	No	No	0	4	7
755	B:B:N293	B:B:V307	7.39	No	No	0	5	3
756	B:B:A309	B:B:N293	6.25	No	No	0	3	5
757	B:B:C294	B:B:L308	4.76	No	No	0	5	7
758	B:B:C294	B:B:L318	3.17	No	No	0	5	6
759	B:B:N295	B:B:W297	3.39	Yes	Yes	2	6	8
760	B:B:N295	B:B:R304	6.03	Yes	Yes	2	6	5
761	B:B:N295	B:B:V307	4.43	Yes	No	0	6	3
762	B:B:R304	B:B:W297	9	Yes	Yes	2	5	8
763	B:B:D298	B:B:K301	8.3	Yes	No	2	9	5
764	B:B:D298	B:B:D303	3.99	Yes	No	2	9	2
765	B:B:L300	G:G:C41	6.35	Yes	No	2	6	7
766	B:B:D303	B:B:K301	8.3	No	No	2	2	5
767	B:B:L308	B:B:W339	12.53	No	Yes	7	7	9
768	B:B:G310	B:B:W339	2.81	No	Yes	0	5	9
769	B:B:H311	B:B:V315	4.15	Yes	No	7	9	7
770	B:B:H311	B:B:T329	5.48	Yes	Yes	7	9	8
771	B:B:H311	B:B:S331	12.55	Yes	No	7	9	9
772	B:B:D333	B:B:H311	10.08	Yes	Yes	7	9	9
773	B:B:H311	B:B:K337	13.1	Yes	Yes	7	9	6
774	B:B:D312	B:B:D333	6.65	No	Yes	0	5	9
775	B:B:N313	B:B:R314	2.41	No	Yes	2	7	8
776	B:B:N313	B:B:W332	6.78	No	Yes	2	7	9
777	B:B:R314	B:B:W332	31.99	Yes	Yes	2	8	9
778	B:B:T329	B:B:V315	4.76	Yes	No	7	8	7
779	B:B:C317	B:B:S316	3.44	No	No	0	7	9
780	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
781	B:B:C317	B:B:G330	1.96	No	No	0	7	5
782	B:B:L318	B:B:T329	2.95	No	Yes	0	6	8
783	B:B:V320	B:B:V327	4.81	No	No	0	7	6
784	B:B:D323	B:B:T321	7.23	No	No	3	7	7
785	B:B:D323	B:B:M325	6.93	No	Yes	0	7	5
786	B:B:G324	G:G:P49	4.06	No	No	0	9	7
787	B:B:M325	G:G:P49	5.03	Yes	No	0	5	7
788	B:B:M325	G:G:V54	4.56	Yes	Yes	0	5	6
789	B:B:M325	G:G:P60	6.71	Yes	No	0	5	9
790	B:B:A326	G:G:F61	4.16	No	Yes	0	7	8
791	B:B:T329	B:B:W339	6.06	Yes	Yes	7	8	9
792	B:B:G330	B:B:L336	3.42	No	Yes	0	5	7
793	B:B:D333	B:B:S331	8.83	Yes	No	7	9	9
794	B:B:D333	B:B:F335	11.94	Yes	Yes	0	9	4
795	B:B:F335	B:B:S334	5.28	Yes	No	0	4	4
796	B:B:F335	B:B:K337	2.48	Yes	Yes	0	4	6
797	B:B:K337	B:B:W339	6.96	Yes	Yes	7	6	9
798	B:B:I338	G:G:F61	5.02	Yes	Yes	3	5	8
799	B:B:N340	G:G:N59	4.09	No	No	0	9	9
800	B:B:N340	G:G:F61	2.42	No	Yes	0	9	8
801	G:G:R13	G:G:V16	2.62	No	Yes	0	6	7
802	G:G:E17	G:G:K20	5.4	No	No	0	6	6
803	G:G:E22	G:G:Q18	6.37	Yes	No	0	9	9
804	G:G:E22	G:G:L19	11.93	Yes	Yes	4	9	9
805	G:G:I25	G:G:R27	6.26	Yes	Yes	4	2	8
806	G:G:K29	G:G:S31	7.65	No	Yes	9	4	9
807	G:G:D36	G:G:K32	13.83	No	No	0	5	5
808	G:G:E42	G:G:M38	10.83	No	No	0	1	4
809	G:G:H44	G:G:Y40	7.62	No	Yes	0	6	6
810	G:G:A43	G:G:H44	2.93	No	No	0	4	6
811	G:G:D48	G:G:P49	4.83	Yes	No	0	9	7
812	G:G:D48	G:G:L51	5.43	Yes	Yes	0	9	6
813	G:G:P55	G:G:V54	5.3	No	Yes	13	5	6
814	G:G:E58	G:G:V54	5.7	No	Yes	13	5	6
815	G:G:N59	G:G:V54	2.96	No	Yes	0	9	6
816	G:G:E58	G:G:P55	3.14	No	No	13	5	5
817	G:G:A56	G:G:R62	5.53	No	No	0	4	7
818	G:G:N59	G:G:R62	7.23	No	No	0	9	7
819	R:R:F174	R:R:V13	2.62	Yes	No	0	4	4
820	R:R:D14	R:R:Y165	18.39	No	No	0	6	2
821	R:R:D14	R:R:E264	7.8	No	No	0	6	3
822	R:R:D83	R:R:S15	4.42	No	No	1	4	4
823	R:R:H167	R:R:S15	4.18	Yes	No	0	3	4
824	R:R:F267	R:R:S15	11.89	Yes	No	1	4	4
825	R:R:F267	R:R:R16	2.14	Yes	No	0	4	4
826	R:R:R16	R:R:S268	5.27	No	No	0	4	2
827	R:R:H19	R:R:V17	6.92	No	No	0	5	4
828	R:R:D18	R:R:P22	11.27	No	Yes	1	6	5
829	R:R:D18	R:R:F79	3.58	No	Yes	1	6	4
830	R:R:D18	R:R:H271	2.52	No	Yes	1	6	4
831	R:R:H19	R:R:L20	2.57	No	No	0	5	3
832	R:R:H19	R:R:H82	15.53	No	No	0	5	4
833	R:R:F21	R:R:P22	5.78	No	Yes	0	6	5
834	R:R:F21	R:R:S272	2.64	No	No	0	6	5
835	R:R:P22	R:R:P23	5.84	Yes	Yes	1	5	6
836	R:R:F79	R:R:P22	7.22	Yes	Yes	1	4	5
837	R:R:A275	R:R:P22	3.74	No	Yes	0	4	5
838	R:R:F79	R:R:P23	2.89	Yes	Yes	1	4	6
839	R:R:L80	R:R:P23	6.57	No	Yes	0	4	6
840	R:R:L25	R:R:L279	2.77	No	No	0	6	5
841	R:R:L72	R:R:Y26	7.03	Yes	Yes	1	8	8
842	R:R:F79	R:R:Y26	3.09	Yes	Yes	1	4	8
843	R:R:F99	R:R:Y26	4.13	Yes	Yes	1	6	8
844	R:R:A275	R:R:Y26	4	No	Yes	0	4	8
845	R:R:S278	R:R:Y26	5.09	No	Yes	0	6	8
846	R:R:F28	R:R:V32	7.87	No	No	0	4	5
847	R:R:I69	R:R:V29	4.61	No	No	0	5	7
848	R:R:L72	R:R:V29	2.98	Yes	No	0	8	7
849	R:R:S278	R:R:V29	6.46	No	No	0	6	7
850	R:R:G31	R:R:I30	3.53	No	No	0	5	7
851	R:R:I30	R:R:L34	4.28	No	No	0	7	6
852	R:R:I30	R:R:P73	5.08	No	No	0	7	9
853	R:R:T36	R:R:V32	3.17	No	No	0	7	5
854	R:R:V282	R:R:V32	4.81	No	No	0	6	5
855	R:R:G33	R:R:T36	3.64	No	No	0	8	7
856	R:R:I69	R:R:L34	8.56	No	No	0	5	6
857	R:R:P285	R:R:T36	6.99	No	No	0	9	7
858	R:R:D65	R:R:N37	6.73	Yes	No	0	9	9
859	R:R:L66	R:R:N37	2.75	No	No	0	7	9
860	R:R:N37	R:R:P285	13.03	No	No	0	9	9
861	R:R:L39	R:R:V299	7.45	No	No	0	6	5
862	R:R:L303	R:R:L39	2.77	No	No	0	7	6
863	R:R:A40	R:R:C289	3.61	No	No	0	8	6
864	R:R:L41	R:R:M59	4.24	No	Yes	0	7	5
865	R:R:L41	R:R:S62	3	No	No	0	7	8
866	R:R:W42	R:R:Y45	2.89	No	No	0	3	1
867	R:R:D298	R:R:W42	10.05	Yes	No	0	5	3
868	R:R:A302	R:R:W42	5.19	No	No	0	5	3
869	R:R:A43	R:R:D298	4.63	No	Yes	0	6	5
870	R:R:A44	R:R:M59	3.22	No	Yes	0	6	5
871	R:R:R49	R:R:Y45	11.32	No	No	0	6	1
872	R:R:M59	R:R:Y45	2.39	Yes	No	0	5	1
873	R:R:R46	R:R:R49	6.4	No	No	0	5	6
874	R:R:D298	R:R:R46	3.57	Yes	No	0	5	5
875	R:R:Q47	R:R:Q50	3.84	No	No	0	5	6
876	R:R:N52	R:R:Q47	9.24	No	No	0	7	5
877	R:R:V48	R:R:V56	3.21	No	Yes	1	5	6
878	R:R:M59	R:R:V48	4.56	Yes	No	0	5	5
879	R:R:H51	R:R:V133	6.92	No	Yes	0	6	4
880	R:R:L54	R:R:N52	4.12	Yes	No	0	7	7
881	R:R:E53	R:R:Y57	4.49	Yes	Yes	1	6	7
882	R:R:D116	R:R:E53	14.29	Yes	Yes	1	8	6
883	R:R:E53	R:R:R131	5.82	Yes	Yes	1	6	7
884	R:R:A136	R:R:E53	3.02	No	Yes	1	7	6
885	R:R:L54	R:R:L58	4.15	Yes	Yes	0	7	7
886	R:R:I113	R:R:L54	2.85	Yes	Yes	1	8	7
887	R:R:D116	R:R:L54	4.07	Yes	Yes	1	8	7
888	R:R:L54	R:R:R117	4.86	Yes	Yes	1	7	9
889	R:R:G55	R:R:L58	5.13	No	Yes	0	7	7
890	R:R:A136	R:R:V56	5.09	No	Yes	1	7	6
891	R:R:V137	R:R:V56	3.21	No	Yes	1	4	6
892	R:R:C112	R:R:Y57	5.38	No	Yes	0	6	7
893	R:R:I113	R:R:Y57	3.63	Yes	Yes	1	8	7
894	R:R:D116	R:R:Y57	8.05	Yes	Yes	1	8	7
895	R:R:A136	R:R:Y57	5.34	No	Yes	1	7	7
896	R:R:V139	R:R:Y57	6.31	No	Yes	0	4	7
897	R:R:S140	R:R:Y57	2.54	No	Yes	1	6	7
898	R:R:L58	R:R:Y288	3.52	Yes	Yes	0	7	9
899	R:R:C289	R:R:L58	4.76	No	Yes	0	6	7
900	R:R:F109	R:R:N60	14.5	Yes	No	1	7	9
901	R:R:N60	R:R:S140	8.94	No	No	1	9	6
902	R:R:N60	R:R:W144	11.3	No	Yes	1	9	9
903	R:R:D65	R:R:L61	2.71	Yes	Yes	1	9	9
904	R:R:L61	R:R:S106	3	Yes	No	1	9	9
905	R:R:F109	R:R:L61	2.44	Yes	Yes	1	7	9
906	R:R:L110	R:R:L61	4.15	No	Yes	1	8	9
907	R:R:D284	R:R:L61	9.5	Yes	Yes	1	9	9
908	R:R:I63	R:R:W144	2.35	No	Yes	0	5	9
909	R:R:A64	R:R:I105	3.25	No	Yes	1	8	6
910	R:R:A64	R:R:W144	2.59	No	Yes	1	8	9
911	R:R:D65	R:R:S106	4.42	Yes	No	1	9	9
912	R:R:C281	R:R:D65	6.22	No	Yes	0	8	9
913	R:R:D284	R:R:D65	7.98	Yes	Yes	1	9	9
914	R:R:L67	R:R:N102	5.49	No	Yes	0	6	8
915	R:R:L72	R:R:Y68	5.86	Yes	Yes	1	8	5
916	R:R:F99	R:R:Y68	8.25	Yes	Yes	1	6	5
917	R:R:N102	R:R:Y68	8.14	Yes	Yes	0	8	5
918	R:R:I103	R:R:Y68	3.63	Yes	Yes	1	7	5
919	R:R:S278	R:R:Y68	6.36	No	Yes	0	6	5
920	R:R:C281	R:R:Y68	4.03	No	Yes	0	8	5
921	R:R:F95	R:R:T71	7.78	Yes	No	0	5	6
922	R:R:I98	R:R:T71	9.12	No	No	0	5	6
923	R:R:F99	R:R:L72	2.44	Yes	Yes	1	6	8
924	R:R:L74	R:R:W85	6.83	No	Yes	1	6	9
925	R:R:F95	R:R:L74	12.18	Yes	No	1	5	6
926	R:R:W75	R:R:Y78	7.72	Yes	Yes	1	6	5
927	R:R:F79	R:R:W75	3.01	Yes	Yes	1	4	6
928	R:R:W75	R:R:W85	13.12	Yes	Yes	1	6	9
929	R:R:G96	R:R:W75	4.22	No	Yes	0	6	6
930	R:R:F99	R:R:W75	28.06	Yes	Yes	1	6	6
931	R:R:W75	R:R:Y100	3.86	Yes	Yes	1	6	5
932	R:R:C170	R:R:W75	6.53	Yes	Yes	1	9	6
933	R:R:F79	R:R:Y78	10.32	Yes	Yes	1	4	5
934	R:R:W85	R:R:Y78	10.61	Yes	Yes	1	9	5
935	R:R:C170	R:R:Y78	5.38	Yes	Yes	1	9	5
936	R:R:E172	R:R:Y78	4.49	No	Yes	0	5	5
937	R:R:F79	R:R:H271	9.05	Yes	Yes	1	4	4
938	R:R:H81	R:R:N84	6.38	No	No	0	4	4
939	R:R:H81	R:R:I86	2.65	No	No	0	4	3
940	R:R:D83	R:R:F267	7.17	No	Yes	1	4	4
941	R:R:N84	R:R:T168	2.92	No	No	0	4	4
942	R:R:H87	R:R:W85	4.23	No	Yes	1	7	9
943	R:R:S91	R:R:W85	8.65	No	Yes	1	4	9
944	R:R:C92	R:R:W85	9.14	No	Yes	1	9	9
945	R:R:F95	R:R:W85	2	Yes	Yes	1	5	9
946	R:R:L160	R:R:W85	2.28	No	Yes	0	5	9
947	R:R:C170	R:R:W85	14.37	Yes	Yes	1	9	9
948	R:R:H87	R:R:I86	6.63	No	No	0	7	3
949	R:R:H87	R:R:S91	4.18	No	No	1	7	4
950	R:R:G88	R:R:P89	4.06	No	No	0	7	4
951	R:R:C170	R:R:C92	5.46	Yes	No	1	9	9
952	R:R:E159	R:R:K93	12.15	No	No	0	4	7
953	R:R:F95	R:R:L94	6.09	Yes	No	0	5	5
954	R:R:F171	R:R:G96	4.52	Yes	No	0	4	6
955	R:R:F97	R:R:S101	3.96	No	No	0	5	5
956	R:R:F97	R:R:L148	4.87	No	No	0	5	4
957	R:R:F97	R:R:L155	8.53	No	No	0	5	4
958	R:R:I98	R:R:N102	4.25	No	Yes	0	5	8
959	R:R:F99	R:R:Y100	9.28	Yes	Yes	1	6	5
960	R:R:F99	R:R:L274	4.87	Yes	No	1	6	5
961	R:R:F171	R:R:Y100	4.13	Yes	Yes	1	4	5
962	R:R:E172	R:R:Y100	3.37	No	Yes	0	5	5
963	R:R:R187	R:R:Y100	2.06	Yes	Yes	0	5	5
964	R:R:Y100	R:R:Y242	1.99	Yes	Yes	1	5	7
965	R:R:L274	R:R:Y100	3.52	No	Yes	1	5	5
966	R:R:E147	R:R:S101	2.87	Yes	No	0	7	5
967	R:R:I105	R:R:N102	4.25	Yes	Yes	0	6	8
968	R:R:I103	R:R:Y104	8.46	Yes	Yes	0	7	7
969	R:R:F239	R:R:I103	8.79	Yes	Yes	1	9	7
970	R:R:I103	R:R:T277	3.04	Yes	No	1	7	8
971	R:R:E147	R:R:Y104	6.73	Yes	Yes	0	7	7
972	R:R:R187	R:R:Y104	13.38	Yes	Yes	0	5	7
973	R:R:G191	R:R:Y104	2.9	No	Yes	0	6	7
974	R:R:H243	R:R:Y104	9.8	Yes	Yes	0	8	7
975	R:R:F109	R:R:I105	2.51	Yes	Yes	1	7	6
976	R:R:I105	R:R:W144	9.4	Yes	Yes	1	6	9
977	R:R:E147	R:R:I105	15.03	Yes	Yes	0	7	6
978	R:R:D284	R:R:S106	2.94	Yes	No	1	9	9
979	R:R:F192	R:R:I107	3.77	Yes	No	1	8	7
980	R:R:I107	R:R:V235	3.07	No	No	0	7	9
981	R:R:F239	R:R:I107	8.79	Yes	No	1	9	7
982	R:R:F109	R:R:S140	3.96	Yes	No	1	7	6
983	R:R:F109	R:R:V143	9.18	Yes	No	0	7	6
984	R:R:F109	R:R:W144	8.02	Yes	Yes	1	7	9
985	R:R:D284	R:R:L110	6.79	Yes	No	1	9	8
986	R:R:L110	R:R:Y288	8.21	No	Yes	1	8	9
987	R:R:C111	R:R:P195	3.77	No	No	0	7	9
988	R:R:C111	R:R:L198	4.76	No	No	0	7	5
989	R:R:C111	R:R:M199	3.24	No	No	0	7	7
990	R:R:I113	R:R:R117	5.01	Yes	Yes	1	8	9
991	R:R:I113	R:R:Y288	4.84	Yes	Yes	1	8	9
992	R:R:M199	R:R:S114	6.13	No	No	0	7	9
993	R:R:C202	R:R:S114	5.16	No	No	0	6	9
994	R:R:S114	R:R:Y203	5.09	No	Yes	0	9	8
995	R:R:C202	R:R:V115	3.42	No	No	0	6	5
996	R:R:R117	R:R:Y203	8.23	Yes	Yes	1	9	8
997	R:R:R117	R:R:Y288	3.09	Yes	Yes	1	9	9
998	R:R:L119	R:R:Y118	2.34	No	Yes	0	5	8
999	R:R:A122	R:R:Y118	6.67	No	Yes	14	6	8
1000	R:R:H123	R:R:Y118	8.71	No	Yes	14	6	8
1001	R:R:C202	R:R:Y118	4.03	No	Yes	0	6	8
1002	R:R:G205	R:R:Y118	2.9	No	Yes	0	4	8
1003	R:R:I206	R:R:Y118	2.42	No	Yes	0	8	8
1004	R:R:F127	R:R:L119	3.65	Yes	No	0	5	5
1005	R:R:A120	R:R:R131	2.77	No	Yes	1	7	7
1006	R:R:A122	R:R:H123	4.39	No	No	14	6	6
1007	R:R:F127	R:R:H123	6.79	Yes	No	0	5	6
1008	R:R:F127	R:R:R126	3.21	Yes	No	0	5	4
1009	R:R:F127	R:R:L130	3.65	Yes	No	0	5	5
1010	R:R:L130	R:R:R129	2.43	No	No	0	5	4
1011	R:R:R129	R:R:R132	3.2	No	Yes	0	4	6
1012	R:R:R132	R:R:T135	2.59	Yes	No	0	6	4
1013	R:R:E147	R:R:N151	5.26	Yes	No	0	7	6
1014	R:R:G149	R:R:S152	3.71	No	No	0	3	4
1015	R:R:N151	R:R:Y186	5.81	No	No	0	6	4
1016	R:R:A153	R:R:W179	2.59	No	Yes	0	8	3
1017	R:R:E159	R:R:P154	3.14	No	Yes	1	4	6
1018	R:R:F171	R:R:P154	8.67	Yes	Yes	1	4	6
1019	R:R:P154	R:R:W179	4.05	Yes	Yes	1	6	3
1020	R:R:M183	R:R:P154	3.35	No	Yes	1	5	6
1021	R:R:H157	R:R:W179	29.62	No	Yes	0	4	3
1022	R:R:E159	R:R:F171	19.82	No	Yes	1	4	4
1023	R:R:L160	R:R:T168	2.95	No	No	0	5	4
1024	R:R:F161	R:R:K173	13.65	No	No	0	3	4
1025	R:R:R162	R:R:T168	7.76	No	No	0	2	4
1026	R:R:D163	R:R:H167	12.61	No	Yes	0	1	3
1027	R:R:R164	R:R:Y165	2.06	No	No	0	2	2
1028	R:R:H167	R:R:Y165	6.53	Yes	No	0	3	2
1029	R:R:F169	R:R:H167	5.66	No	Yes	0	2	3
1030	R:R:E172	R:R:F169	7	No	No	0	5	2
1031	R:R:F169	R:R:F174	12.86	No	Yes	0	2	4
1032	R:R:E177	R:R:K173	8.1	Yes	No	0	4	4
1033	R:R:E263	R:R:F174	7	No	Yes	0	3	4
1034	R:R:F174	R:R:F267	6.43	Yes	Yes	0	4	4
1035	R:R:M176	R:R:V180	3.04	Yes	Yes	1	3	5
1036	R:R:M176	R:R:N184	2.8	Yes	Yes	1	3	5
1037	R:R:M176	R:R:R249	6.2	Yes	Yes	1	3	5
1038	R:R:M176	R:R:S250	4.6	Yes	No	1	3	5
1039	R:R:M176	R:R:Y253	10.78	Yes	No	0	3	3
1040	R:R:E263	R:R:M176	2.71	No	Yes	1	3	3
1041	R:R:E177	R:R:W179	10.9	Yes	Yes	1	4	3
1042	R:R:E177	R:R:V180	2.85	Yes	Yes	1	4	5
1043	R:R:V180	R:R:W179	11.03	Yes	Yes	1	5	3
1044	R:R:M183	R:R:W179	4.65	No	Yes	1	5	3
1045	R:R:N184	R:R:V180	4.43	Yes	Yes	1	5	5
1046	R:R:A181	R:R:Y253	2.67	No	No	0	2	3
1047	R:R:L185	R:R:W182	2.28	No	No	0	4	2
1048	R:R:L254	R:R:W182	2.28	No	No	0	1	2
1049	R:R:M183	R:R:R187	4.96	No	Yes	0	5	5
1050	R:R:N184	R:R:R187	3.62	Yes	Yes	0	5	5
1051	R:R:L246	R:R:N184	13.73	Yes	Yes	1	6	5
1052	R:R:N184	R:R:R249	2.41	Yes	Yes	1	5	5
1053	R:R:N184	R:R:S250	7.45	Yes	No	1	5	5
1054	R:R:V190	R:R:Y186	11.36	No	No	0	4	4
1055	R:R:F189	R:R:V188	2.62	No	Yes	0	4	4
1056	R:R:H243	R:R:V188	5.54	Yes	Yes	0	8	4
1057	R:R:L246	R:R:V188	2.98	Yes	Yes	0	6	4
1058	R:R:F189	R:R:L193	2.44	No	No	0	4	5
1059	R:R:G191	R:R:P195	4.06	No	No	0	6	9
1060	R:R:F192	R:R:L193	6.09	Yes	No	0	8	5
1061	R:R:F192	R:R:W196	5.01	Yes	Yes	1	8	5
1062	R:R:F192	R:R:L236	2.44	Yes	No	1	8	5
1063	R:R:F192	R:R:F239	8.57	Yes	Yes	1	8	9
1064	R:R:F192	R:R:H243	7.92	Yes	Yes	0	8	8
1065	R:R:F194	R:R:P195	4.33	No	No	0	5	9
1066	R:R:F194	R:R:L198	3.65	No	No	0	5	5
1067	R:R:L200	R:R:W196	3.42	No	Yes	0	3	5
1068	R:R:V235	R:R:W196	6.13	No	Yes	0	9	5
1069	R:R:L236	R:R:W196	13.67	No	Yes	1	5	5
1070	R:R:I232	R:R:L200	4.28	No	No	0	7	3
1071	R:R:I206	R:R:Y203	4.84	No	Yes	0	8	8
1072	R:R:A228	R:R:Y203	4	No	Yes	0	7	8
1073	R:R:L231	R:R:Y203	4.69	No	Yes	1	7	8
1074	R:R:Y203	R:R:Y288	1.99	Yes	Yes	1	8	9
1075	R:R:R204	R:R:R208	9.6	No	No	0	3	4
1076	R:R:G205	R:R:R208	3	No	No	0	4	4
1077	R:R:K225	R:R:L207	7.05	No	No	0	5	4
1078	R:R:A228	R:R:L207	4.73	No	No	0	7	4
1079	R:R:K221	R:R:V210	3.04	No	No	0	6	8
1080	R:R:I224	R:R:V210	6.14	No	No	1	6	8
1081	R:R:S213	R:R:T216	6.4	No	Yes	0	6	3
1082	R:R:E220	R:R:T216	7.06	No	Yes	1	5	3
1083	R:R:K221	R:R:T216	6.01	No	Yes	0	6	3
1084	R:R:Q219	R:R:V222	4.3	No	No	0	4	5
1085	R:R:R226	R:R:V222	6.54	No	No	0	6	5
1086	R:R:K225	R:R:L229	4.23	No	No	0	5	4
1087	R:R:L231	R:R:L287	5.54	No	Yes	1	7	8
1088	R:R:L231	R:R:Y288	12.89	No	Yes	1	7	9
1089	R:R:I234	R:R:L287	4.28	No	Yes	0	6	8
1090	R:R:A240	R:R:L236	3.15	No	No	0	5	5
1091	R:R:C238	R:R:F239	2.79	Yes	Yes	1	7	9
1092	R:R:C238	R:R:N280	6.3	Yes	No	1	7	9
1093	R:R:F239	R:R:T277	7.78	Yes	No	1	9	8
1094	R:R:F239	R:R:N280	8.46	Yes	No	1	9	9
1095	R:R:H243	R:R:Y242	5.44	Yes	Yes	0	8	7
1096	R:R:L246	R:R:Y242	3.52	Yes	Yes	1	6	7
1097	R:R:Y242	R:R:Y270	8.94	Yes	Yes	1	7	4
1098	R:R:S273	R:R:Y242	6.36	No	Yes	0	7	7
1099	R:R:L274	R:R:Y242	11.72	No	Yes	1	5	7
1100	R:R:L245	R:R:S248	3	No	No	0	4	5
1101	R:R:L245	R:R:V266	4.47	No	No	0	4	5
1102	R:R:L246	R:R:R249	2.43	Yes	Yes	1	6	5
1103	R:R:L246	R:R:Y270	3.52	Yes	Yes	1	6	4
1104	R:R:F262	R:R:S248	2.64	Yes	No	0	1	5
1105	R:R:F262	R:R:R249	2.14	Yes	Yes	0	1	5
1106	R:R:E263	R:R:R249	15.12	No	Yes	1	3	5
1107	R:R:R249	R:R:Y270	14.4	Yes	Yes	1	5	4
1108	R:R:R256	R:R:V252	3.92	No	No	0	2	2
1109	R:R:F262	R:R:V252	7.87	Yes	No	0	1	2
1110	R:R:P257	R:R:Y253	5.56	No	No	0	1	3
1111	R:R:D259	R:R:R256	13.1	No	No	0	4	2
1112	R:R:P257	R:R:W258	8.11	No	No	0	1	1
1113	R:R:D259	R:R:G261	3.35	No	No	0	4	3
1114	R:R:C260	R:R:E264	3.04	No	No	0	7	3
1115	R:R:F262	R:R:V266	17.04	Yes	No	0	1	5
1116	R:R:F267	R:R:H271	6.79	Yes	Yes	1	4	4
1117	R:R:H271	R:R:Y270	5.44	Yes	Yes	1	4	4
1118	R:R:F276	R:R:L279	7.31	No	No	0	7	5
1119	R:R:D284	R:R:N280	9.42	Yes	No	1	9	9
1120	R:R:I286	R:R:L290	2.85	No	No	0	6	7
1121	R:R:L287	R:R:Y288	2.34	Yes	Yes	1	8	9
1122	R:R:G294	R:R:N292	3.39	No	No	0	7	8
1123	R:R:A295	R:R:N292	3.13	No	No	0	8	8
1124	R:R:E293	R:R:R296	13.96	No	No	0	5	8
1125	R:R:D298	R:R:V299	4.38	Yes	No	0	5	5
1126	A:A:A226	A:A:G206	1.95	No	No	0	9	8
1127	B:B:A140	B:B:G141	1.95	No	No	0	5	5
1128	B:B:A305	B:B:G306	1.95	No	No	0	4	4
1129	B:B:A193	B:B:P194	1.87	No	No	0	4	4
1130	R:R:A240	R:R:P241	1.87	No	No	0	5	9
1131	B:B:G77	B:B:S98	1.86	No	No	0	8	8
1132	R:R:G294	R:R:S297	1.86	No	No	0	7	5
1133	B:B:G41	B:B:V40	1.84	No	No	0	1	3
1134	A:A:T204	B:B:G141	1.82	No	No	0	9	5
1135	B:B:G182	B:B:T181	1.82	No	No	0	6	2
1136	R:R:A122	R:R:A209	1.79	No	No	0	6	5
1137	R:R:P175	R:R:V13	1.77	No	No	0	4	4
1138	R:R:P23	R:R:V76	1.77	Yes	No	0	6	7
1139	A:A:P326	A:A:T325	1.75	No	No	0	1	2
1140	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1141	G:G:P53	G:G:T52	1.75	No	No	0	8	4
1142	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
1143	A:A:G47	A:A:L46	1.71	No	Yes	0	9	8
1144	B:B:A28	G:G:S31	1.71	No	Yes	0	4	9
1145	B:B:G174	B:B:L139	1.71	No	Yes	0	4	9
1146	R:R:C238	R:R:V237	1.71	Yes	No	0	7	6
1147	R:R:A269	R:R:S272	1.71	No	No	0	4	5
1148	A:A:A337	A:A:V301	1.7	No	Yes	0	8	7
1149	B:B:A11	G:G:V16	1.7	No	Yes	0	5	7
1150	R:R:A108	R:R:V143	1.7	No	No	0	5	6
1151	R:R:C70	R:R:T71	1.69	No	No	0	4	6
1152	A:A:D354	A:A:G353	1.68	No	No	0	3	4
1153	B:B:D246	B:B:G272	1.68	Yes	No	0	9	4
1154	B:B:D290	B:B:G272	1.68	Yes	No	0	6	4
1155	R:R:A150	R:R:T146	1.68	No	No	0	5	4
1156	A:A:G355	R:R:E217	1.64	No	No	0	2	4
1157	B:B:E130	B:B:G131	1.64	Yes	No	0	3	4
1158	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
1159	R:R:L34	R:R:P35	1.64	No	No	0	6	4
1160	R:R:L160	R:R:P89	1.64	No	No	0	5	4
1161	A:A:I26	B:B:A92	1.62	No	No	0	9	6
1162	B:B:I33	G:G:A34	1.62	No	No	0	3	6
1163	R:R:S141	R:R:V142	1.62	No	No	0	3	3
1164	R:R:A283	R:R:I234	1.62	No	No	0	6	6
1165	A:A:K203	B:B:A140	1.61	No	No	0	7	5
1166	A:A:S54	A:A:T55	1.6	No	No	0	9	9
1167	B:B:S31	B:B:T29	1.6	No	No	0	1	3
1168	B:B:S207	B:B:T223	1.6	Yes	No	0	5	2
1169	B:B:S265	B:B:T249	1.6	No	Yes	0	2	6
1170	R:R:V133	R:R:V48	1.6	Yes	No	1	4	5
1171	R:R:V133	R:R:V56	1.6	Yes	Yes	1	4	6
1172	R:R:V133	R:R:V137	1.6	Yes	No	1	4	4
1173	A:A:T40	A:A:V36	1.59	No	No	0	7	2
1174	R:R:C38	R:R:L66	1.59	No	No	0	2	7
1175	R:R:T146	R:R:V142	1.59	No	No	0	4	3
1176	R:R:C238	R:R:L279	1.59	Yes	No	0	7	5
1177	B:B:L7	G:G:A12	1.58	No	No	0	8	5
1178	B:B:A299	B:B:L285	1.58	No	Yes	0	5	6
1179	R:R:A181	R:R:L254	1.58	No	No	0	2	1
1180	A:A:A19	B:B:N88	1.56	No	Yes	0	4	7
1181	B:B:I33	G:G:S31	1.55	No	Yes	0	3	9
1182	B:B:A24	B:B:D20	1.54	No	No	0	3	2
1183	G:G:A35	G:G:D36	1.54	No	No	0	2	5
1184	R:R:I27	R:R:V76	1.54	No	No	0	4	7
1185	B:B:M262	B:B:S31	1.53	Yes	No	0	4	1
1186	B:B:A21	B:B:Q17	1.52	No	No	0	4	4
1187	G:G:K20	G:G:V16	1.52	No	Yes	0	6	7
1188	R:R:K134	R:R:V133	1.52	No	Yes	0	4	4
1189	A:A:A298	A:A:E299	1.51	No	No	0	4	6
1190	R:R:L155	R:R:S152	1.5	No	No	0	4	4
1191	R:R:L227	R:R:S230	1.5	No	No	0	7	5
1192	R:R:L287	R:R:S230	1.5	Yes	No	0	8	5
1193	B:B:L14	G:G:V16	1.49	No	Yes	0	8	7
1194	R:R:L247	R:R:V188	1.49	No	Yes	0	5	4
1195	R:R:L227	R:R:V291	1.49	No	No	0	7	6
1196	G:G:L51	G:G:T52	1.47	Yes	No	0	6	4
1197	A:A:I382	A:A:M386	1.46	Yes	No	0	6	3
1198	A:A:I383	A:A:M386	1.46	Yes	No	0	8	3
1199	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1200	B:B:D170	B:B:T177	1.45	No	No	0	9	4
1201	A:A:K24	A:A:K28	1.44	No	No	0	4	4
1202	A:A:F312	A:A:P313	1.44	Yes	No	0	8	6
1203	G:G:E58	G:G:S57	1.44	No	No	0	5	6
1204	B:B:K15	B:B:N16	1.4	No	No	0	6	1
1205	G:G:D26	G:G:I25	1.4	No	Yes	0	1	2
1206	A:A:K34	A:A:Q31	1.36	No	No	0	4	4
1207	R:R:D77	R:R:L80	1.36	No	No	0	4	4
1208	B:B:L7	B:B:Q6	1.33	No	No	0	8	1
1209	R:R:A150	R:R:Y186	1.33	No	No	0	5	4
1210	A:A:F208	A:A:S205	1.32	No	No	0	5	7
1211	R:R:F156	R:R:S152	1.32	No	No	0	4	4
1212	A:A:R333	A:A:V301	1.31	No	Yes	0	5	7
1213	A:A:D323	A:A:E322	1.3	No	No	0	4	1
1214	A:A:R61	A:A:T210	1.29	No	No	0	8	7
1215	A:A:R283	A:A:T284	1.29	No	No	0	3	4
1216	B:B:Q13	B:B:Q9	1.28	No	No	0	1	3
1217	R:R:D83	R:R:H82	1.26	No	No	0	4	4
1218	R:R:K223	R:R:R226	1.24	No	No	0	7	6
1219	R:R:L290	R:R:R296	1.21	No	No	0	7	8
1220	B:B:D212	B:B:R214	1.19	Yes	No	0	9	9
1221	A:A:E309	A:A:F315	1.17	No	Yes	0	4	6
1222	R:R:Q211	R:R:R208	1.17	No	No	0	4	4
1223	R:R:E177	R:R:R178	1.16	Yes	No	0	4	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:H41	5.384	5	1	6
2	A:A:L45	5.2325	4	0	8
3	A:A:L46	3.7925	4	2	8
4	A:A:N50	6.39333	6	1	9
5	A:A:K53	4.5125	4	1	9
6	A:A:Y63	3.8575	4	1	9
7	A:A:H64	3.71	4	1	8
8	A:A:F212	5.86286	7	1	9
9	A:A:V217	3.804	5	1	5
10	A:A:F219	6.614	5	1	8
11	A:A:H220	9.502	5	2	7
12	A:A:F222	8.50333	6	2	7
13	A:A:Q227	6.0575	4	2	9
14	A:A:R231	6.5925	4	2	9
15	A:A:K233	5.56714	7	2	9
16	A:A:W234	6.11833	6	2	9
17	A:A:F238	8.095	6	2	9
18	A:A:I244	3.61	4	0	8
19	A:A:I245	4.234	5	1	7
20	A:A:F246	3.278	5	2	9
21	A:A:V247	4.448	5	1	7
22	A:A:V248	4.87	4	2	7
23	A:A:D249	7.9475	4	1	8
24	A:A:Y253	14.342	5	2	8
25	A:A:R265	7.414	5	1	9
26	A:A:L266	3.565	4	2	8
27	A:A:L270	4.73667	6	2	6
28	A:A:F273	4.385	8	2	9
29	A:A:I276	4.32	5	2	8
30	A:A:W277	7.32857	7	2	6
31	A:A:N279	6.34	4	2	8
32	A:A:W281	8.34167	6	2	5
33	A:A:I288	5.058	5	1	9
34	A:A:L289	4.722	5	2	9
35	A:A:F290	4.7975	8	1	9
36	A:A:L291	4.22667	6	2	8
37	A:A:N292	4.938	5	1	9
38	A:A:K293	6.068	5	1	9
39	A:A:Q294	6.39	4	2	6
40	A:A:K300	5.8975	4	2	9
41	A:A:V301	2.7	4	0	7
42	A:A:F312	5.53286	7	2	8
43	A:A:F315	5.93	5	2	6
44	A:A:Y318	5.838	5	2	6
45	A:A:Y339	6.892	5	2	3
46	A:A:F340	10.1275	4	2	7
47	A:A:R342	6.04333	6	2	4
48	A:A:E344	7.0725	4	2	5
49	A:A:F345	7.25	6	2	8
50	A:A:Y360	9.62667	6	1	8
51	A:A:F363	8.244	5	2	5
52	A:A:T364	5.344	5	1	9
53	A:A:N371	4.9125	4	1	9
54	A:A:R373	5.125	4	1	5
55	A:A:R374	8.11	4	1	4
56	A:A:I375	3.7	4	1	9
57	A:A:F376	4.34143	7	1	8
58	A:A:D378	9.4125	4	1	7
59	A:A:D381	5.89	4	1	8
60	A:A:I382	6.8175	4	1	6
61	A:A:I383	4.01667	6	1	8
62	A:A:R385	5.5425	4	1	5
63	A:A:H387	6.01333	6	1	8
64	A:A:L388	4.705	4	1	8
65	A:A:Y391	6.5725	8	1	4
66	A:A:L394	4.548	5	1	8
67	B:B:I18	3.59	5	4	7
68	B:B:R22	5.935	4	4	6
69	B:B:L30	4.3525	4	0	5
70	B:B:I37	4.208	5	2	2
71	B:B:R49	4.59	4	3	7
72	B:B:L51	8.65	4	3	9
73	B:B:H54	8.26	6	3	9
74	B:B:K57	9.016	5	2	9
75	B:B:I58	4.635	4	3	9
76	B:B:Y59	9.595	4	2	8
77	B:B:M61	3.778	5	3	6
78	B:B:W63	5.87714	7	3	7
79	B:B:L70	5.3325	4	3	5
80	B:B:S72	5.3725	4	3	9
81	B:B:D76	7.6575	4	3	9
82	B:B:K78	5.345	4	0	8
83	B:B:L79	5.178	5	6	7
84	B:B:W82	7.57	7	3	9
85	B:B:S84	5.4	4	3	5
86	B:B:Y85	13.4675	4	3	4
87	B:B:N88	5.57	5	3	7
88	B:B:K89	6.61	6	3	9
89	B:B:H91	6.96	4	6	5
90	B:B:I93	4.6375	4	6	7
91	B:B:L95	5.795	4	6	8
92	B:B:W99	9.15571	7	2	9
93	B:B:Y105	4.192	5	6	6
94	B:B:N110	6.215	4	2	4
95	B:B:Y111	5.255	6	2	4
96	B:B:V112	4.5875	4	6	8
97	B:B:C114	5.01	4	6	8
98	B:B:L117	3.08	6	2	9
99	B:B:I123	3.3525	4	2	6
100	B:B:Y124	4.82125	8	6	6
101	B:B:L126	4.2625	4	6	5
102	B:B:E130	4.71	4	11	3
103	B:B:V133	4.285	4	6	4
104	B:B:L139	6.3025	4	0	9
105	B:B:H142	6.61429	7	2	9
106	B:B:Y145	4.98778	9	2	8
107	B:B:R150	7.2925	4	5	6
108	B:B:F151	4.78571	7	2	9
109	B:B:L152	4.8975	4	0	3
110	B:B:I157	5.5725	4	2	7
111	B:B:S161	8.09	4	2	9
112	B:B:D163	8.4425	4	2	9
113	B:B:C166	3.885	4	5	8
114	B:B:L168	3.4975	4	5	6
115	B:B:W169	8.82333	6	2	8
116	B:B:Q176	6.9825	4	2	4
117	B:B:F180	6.47333	6	5	7
118	B:B:H183	7.04286	7	5	9
119	B:B:D186	5.976	5	2	9
120	B:B:V187	4.725	4	5	9
121	B:B:L190	5.03	5	5	5
122	B:B:F199	6.67833	6	5	9
123	B:B:V200	7.67	4	4	6
124	B:B:C204	3.74	5	2	7
125	B:B:D205	7.7	4	5	9
126	B:B:S207	4.475	4	5	5
127	B:B:K209	10.6275	4	5	6
128	B:B:L210	5.9075	4	4	5
129	B:B:W211	7.98667	6	5	8
130	B:B:D212	9.165	4	12	9
131	B:B:Q220	8.0375	4	4	7
132	B:B:F222	6.924	5	4	8
133	B:B:H225	10.485	6	4	9
134	B:B:D228	8.754	5	2	9
135	B:B:I232	5.4825	4	4	8
136	B:B:F234	6.2725	4	4	5
137	B:B:F235	6.2675	8	2	6
138	B:B:P236	7.785	4	2	7
139	B:B:F241	6.13571	7	4	6
140	B:B:T243	6.088	5	4	8
141	B:B:D246	6.574	5	2	9
142	B:B:D247	6.91	4	4	9
143	B:B:T249	4.285	4	4	6
144	B:B:R251	8.76429	7	4	8
145	B:B:F253	7.21833	6	4	6
146	B:B:D254	4.196	5	0	9
147	B:B:L255	3.27	4	4	6
148	B:B:R256	6.9775	4	0	9
149	B:B:D258	9.198	5	4	7
150	B:B:Q259	3.85	4	0	6
151	B:B:M262	5.05	4	2	4
152	B:B:Y264	6.74667	6	2	5
153	B:B:H266	12.6575	4	2	4
154	B:B:N268	10.61	4	2	4
155	B:B:I269	4.185	4	2	4
156	B:B:I273	4.545	4	2	6
157	B:B:F278	5.45833	6	2	7
158	B:B:R283	8.4625	4	2	9
159	B:B:L285	4.428	5	2	6
160	B:B:Y289	5.72	6	2	7
161	B:B:D290	5.855	4	2	6
162	B:B:N295	6.08	4	2	6
163	B:B:W297	6.425	6	2	8
164	B:B:D298	9.1325	4	2	9
165	B:B:L300	5.2275	4	2	6
166	B:B:R304	8.95	4	2	5
167	B:B:H311	9.072	5	7	9
168	B:B:R314	11.255	6	2	8
169	B:B:M325	5.8075	4	0	5
170	B:B:T329	4.8125	4	7	8
171	B:B:W332	13.3286	7	2	9
172	B:B:D333	9.375	4	7	9
173	B:B:F335	7.0625	4	0	4
174	B:B:L336	4.47167	6	3	7
175	B:B:K337	7.812	5	7	6
176	B:B:I338	4.254	5	3	5
177	B:B:W339	6.125	6	7	9
178	G:G:V16	2.606	5	0	7
179	G:G:L19	6.495	4	4	9
180	G:G:E22	6.6575	4	4	9
181	G:G:I25	3.9875	4	4	2
182	G:G:R27	5.2275	4	4	8
183	G:G:S31	4.935	4	9	9
184	G:G:Y40	6.7925	4	2	6
185	G:G:D48	6.434	5	0	9
186	G:G:L51	3.935	4	0	6
187	G:G:V54	4.63	4	13	6
188	G:G:F61	5.50143	7	3	8
189	R:R:P22	6.77	5	1	5
190	R:R:P23	4.2675	4	1	6
191	R:R:Y26	4.668	5	1	8
192	R:R:E53	6.646	5	1	6
193	R:R:L54	4.51333	6	1	7
194	R:R:V56	3.2775	4	1	6
195	R:R:Y57	5.10571	7	1	7
196	R:R:L58	4.39	4	0	7
197	R:R:M59	3.6025	4	0	5
198	R:R:L61	4.36	5	1	9
199	R:R:D65	5.612	5	1	9
200	R:R:Y68	6.045	6	1	5
201	R:R:L72	4.5775	4	1	8
202	R:R:W75	9.50286	7	1	6
203	R:R:Y78	7.704	5	1	5
204	R:R:F79	5.59429	7	1	4
205	R:R:W85	7.91444	9	1	9
206	R:R:F95	7.0125	4	1	5
207	R:R:F99	9.505	6	1	6
208	R:R:Y100	4.03	7	1	5
209	R:R:N102	5.5325	4	0	8
210	R:R:I103	5.98	4	1	7
211	R:R:Y104	8.254	5	0	7
212	R:R:I105	6.888	5	1	6
213	R:R:F109	6.76833	6	1	7
214	R:R:I113	4.0825	4	1	8
215	R:R:D116	8.04	4	1	8
216	R:R:R117	4.69571	7	1	9
217	R:R:Y118	4.51167	6	14	8
218	R:R:P124	4.5975	4	1	8
219	R:R:L125	4.994	5	1	5
220	R:R:F127	4.325	4	0	5
221	R:R:R131	6.4875	4	1	7
222	R:R:R132	5.3075	4	0	6
223	R:R:V133	2.648	5	1	4
224	R:R:W144	6.732	5	1	9
225	R:R:E147	7.4725	4	0	7
226	R:R:P154	4.8025	4	1	6
227	R:R:H167	7.245	4	0	3
228	R:R:C170	7.935	4	1	9
229	R:R:F171	9.285	4	1	4
230	R:R:F174	7.2275	4	0	4
231	R:R:M176	5.02167	6	1	3
232	R:R:E177	5.7525	4	1	4
233	R:R:W179	10.4733	6	1	3
234	R:R:V180	5.3375	4	1	5
235	R:R:N184	5.74	6	1	5
236	R:R:R187	6.005	4	0	5
237	R:R:V188	3.1575	4	0	4
238	R:R:F192	5.63333	6	1	8
239	R:R:W196	7.0575	4	1	5
240	R:R:Y203	4.80667	6	1	8
241	R:R:S215	4.65	4	1	4
242	R:R:T216	6.16	4	1	3
243	R:R:C238	3.0975	4	1	7
244	R:R:F239	7.53	6	1	9
245	R:R:Y242	6.32833	6	1	7
246	R:R:H243	7.175	4	0	8
247	R:R:L246	5.236	5	1	6
248	R:R:R249	7.11667	6	1	5
249	R:R:F262	7.4225	4	0	1
250	R:R:F267	6.884	5	1	4
251	R:R:Y270	8.075	4	1	4
252	R:R:H271	5.95	4	1	4
253	R:R:D284	7.326	5	1	9
254	R:R:L287	3.415	4	1	8
255	R:R:Y288	5.26857	7	1	9
256	R:R:D298	5.6575	4	0	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:F212	A:A:F219	96.0846	15	Yes	Yes	1	9	8
2	A:A:F212	A:A:M221	92.8696	2.49	Yes	No	0	9	8
3	A:A:L45	A:A:M221	92.9016	2.83	Yes	No	0	8	8
4	A:A:K53	A:A:L45	95.4245	8.46	Yes	Yes	0	9	8
5	A:A:G47	A:A:K53	99.9983	3.49	No	Yes	0	9	9
6	A:A:G47	A:A:L46	100	1.71	No	Yes	0	9	8
7	A:A:L44	A:A:L46	32.8316	5.54	No	Yes	0	9	8
8	A:A:F238	A:A:L44	24.4609	17.05	Yes	No	0	9	9
9	A:A:C237	A:A:F238	17.762	2.79	No	Yes	2	8	9
10	A:A:C237	B:B:Y59	17.7739	5.38	No	Yes	2	8	8
11	B:B:W332	B:B:Y59	17.4817	13.5	Yes	Yes	2	9	8
12	B:B:S316	B:B:W332	13.5055	4.94	No	Yes	0	9	9
13	A:A:F219	A:A:H41	92.1306	5.66	Yes	Yes	1	8	6
14	A:A:D378	A:A:I288	10.81	11.2	Yes	Yes	1	7	9
15	A:A:H41	A:A:I383	92.0038	5.3	Yes	Yes	1	6	8
16	A:A:I244	A:A:L282	22.8983	4.28	Yes	No	0	8	9
17	A:A:L282	A:A:N279	22.6034	6.87	No	Yes	2	9	8
18	A:A:N279	A:A:W281	22.3876	3.39	Yes	Yes	2	8	5
19	A:A:R231	A:A:W234	54.3668	8	Yes	Yes	2	9	9
20	A:A:I244	A:A:I276	14.7104	2.94	Yes	Yes	0	8	8
21	A:A:K233	B:B:Y145	23.1117	3.58	Yes	Yes	2	9	8
22	A:A:K233	A:A:Q236	14.3097	2.71	Yes	No	2	9	8
23	A:A:Q236	B:B:R314	12.7458	4.67	No	Yes	2	8	8
24	B:B:R314	B:B:W332	10.9666	31.99	Yes	Yes	2	8	9
25	B:B:D290	B:B:R314	29.3539	14.29	Yes	Yes	2	6	8
26	A:A:F246	A:A:I276	32.022	2.51	Yes	Yes	2	9	8
27	A:A:F246	A:A:V248	12.9862	2.62	Yes	Yes	2	9	7
28	A:A:F246	A:A:F273	11.1119	6.43	Yes	Yes	2	9	9
29	A:A:F246	A:A:L289	14.9931	2.44	Yes	Yes	2	9	9
30	A:A:F345	A:A:L270	12.0778	10.96	Yes	Yes	2	8	6
31	A:A:H387	A:A:I383	99.1167	6.63	Yes	Yes	1	8	8
32	A:A:H387	A:A:Y391	76.3332	5.44	Yes	Yes	1	8	4
33	A:A:H387	R:R:R131	23.4912	10.16	Yes	Yes	1	8	7
34	A:A:Y391	R:R:E53	23.5093	5.61	Yes	Yes	1	4	6
35	R:R:E53	R:R:R131	23.4413	5.82	Yes	Yes	1	6	7
36	A:A:Y391	R:R:D116	21.8534	5.75	Yes	Yes	1	4	8
37	A:A:Y391	R:R:R117	30.68	2.06	Yes	Yes	1	4	9
38	B:B:S147	B:B:Y145	30.9412	2.54	No	Yes	0	9	8
39	B:B:S147	B:B:S160	30.8338	4.89	No	No	0	9	6
40	B:B:S160	B:B:V187	27.5046	4.85	No	Yes	0	6	9
41	B:B:H183	B:B:V187	25.5633	5.54	Yes	Yes	5	9	9
42	B:B:H183	B:B:S207	12.3529	2.79	Yes	Yes	5	9	5
43	B:B:S207	B:B:T221	12.1209	3.2	Yes	No	0	5	7
44	B:B:T221	G:G:E22	24.6437	4.23	No	Yes	0	7	9
45	B:B:H183	B:B:K209	12.4401	14.41	Yes	Yes	5	9	6
46	B:B:K209	B:B:T221	12.7534	13.51	Yes	No	0	6	7
47	B:B:I18	G:G:E22	21.9271	4.1	Yes	Yes	4	7	9
48	B:B:I18	B:B:R22	21.0246	5.01	Yes	Yes	4	7	6
49	B:B:D258	B:B:R22	18.8626	13.1	Yes	Yes	4	7	6
50	B:B:L30	B:B:M262	12.9981	7.07	Yes	Yes	0	5	4
51	B:B:D258	B:B:F222	14.0361	4.78	Yes	Yes	4	7	8
52	B:B:C271	B:B:D290	37.1135	3.11	No	Yes	2	5	6
53	B:B:C271	B:B:Y289	36.373	2.69	No	Yes	2	5	7
54	B:B:W297	B:B:Y289	30.056	7.72	Yes	Yes	2	8	7
55	B:B:W297	B:B:Y264	29.404	13.5	Yes	Yes	2	8	5
56	B:B:R314	B:B:T274	11.1378	5.17	Yes	No	2	8	8
57	B:B:S275	B:B:T274	10.9247	3.2	No	No	0	8	8
58	B:B:L318	B:B:S275	10.6334	6.01	No	No	0	6	8
59	R:R:E53	R:R:Y57	43.5516	4.49	Yes	Yes	1	6	7
60	R:R:S140	R:R:Y57	65.0947	2.54	No	Yes	1	6	7
61	R:R:F109	R:R:S140	63.9568	3.96	Yes	No	1	7	6
62	R:R:F109	R:R:I105	62.7029	2.51	Yes	Yes	1	7	6
63	R:R:I105	R:R:N102	40.0343	4.25	Yes	Yes	0	6	8
64	R:R:N102	R:R:Y68	35.4759	8.14	Yes	Yes	0	8	5
65	R:R:F99	R:R:Y68	32.4115	8.25	Yes	Yes	1	6	5
66	R:R:D116	R:R:Y57	21.8278	8.05	Yes	Yes	1	8	7
67	R:R:R117	R:R:Y288	29.1867	3.09	Yes	Yes	1	9	9
68	R:R:L110	R:R:Y288	29.364	8.21	No	Yes	1	8	9
69	R:R:L110	R:R:L61	13.1867	4.15	No	Yes	1	8	9
70	R:R:D65	R:R:L61	12.9506	2.71	Yes	Yes	1	9	9
71	R:R:C281	R:R:D65	24.4286	6.22	No	Yes	0	8	9
72	R:R:C281	R:R:Y68	24.2847	4.03	No	Yes	0	8	5
73	R:R:D284	R:R:L110	16.119	6.79	Yes	No	1	9	8
74	R:R:D284	R:R:D65	12.937	7.98	Yes	Yes	1	9	9
75	R:R:E147	R:R:I105	22.3221	15.03	Yes	Yes	0	7	6
76	R:R:E147	R:R:Y104	18.9477	6.73	Yes	Yes	0	7	7
77	R:R:R187	R:R:Y104	14.8006	13.38	Yes	Yes	0	5	7
78	R:R:L72	R:R:Y68	13.5081	5.86	Yes	Yes	1	8	5
79	R:R:L72	R:R:Y26	10.4144	7.03	Yes	Yes	1	8	8
80	R:R:F79	R:R:Y26	24.275	3.09	Yes	Yes	1	4	8
81	R:R:F79	R:R:H271	15.4335	9.05	Yes	Yes	1	4	4
82	R:R:F267	R:R:H271	16.6436	6.79	Yes	Yes	1	4	4
83	R:R:F99	R:R:Y26	10.415	4.13	Yes	Yes	1	6	8
84	R:R:S278	R:R:Y68	13.5122	6.36	No	Yes	0	6	5
85	R:R:S278	R:R:Y26	10.4199	5.09	No	Yes	0	6	8
86	R:R:F99	R:R:W75	14.6609	28.06	Yes	Yes	1	6	6
87	A:A:I244	A:A:L44	10.3685	4.28	Yes	No	0	8	9
88	A:A:I276	A:A:L46	29.017	4.28	Yes	Yes	2	8	8
89	B:B:M262	B:B:Y264	14.4446	8.38	Yes	Yes	2	4	5
90	A:A:L46	A:A:R231	39.9868	3.64	Yes	Yes	2	8	9
91	A:A:W234	B:B:Y145	48.6612	4.82	Yes	Yes	2	9	8
92	A:A:W281	B:B:R314	19.8754	9	Yes	Yes	2	5	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8ZFC

PDB Summary
PDB	8ZFC
Class	A
SubFamily	Orphan
Type	Orphan
SubType	GPR4
Species	Mus Musculus
Ligand	-
Other Ligand(s)	-
Protein Partners	chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution	2.68
Date	2025-02-26
D.O.I.	doi.org/10.1016/j.cell.2024.12.001

Net Summary
I_min	1.96
Number of Linked Nodes	872
Number of Links	1223
Number of Hubs	256
Number of Links mediated by Hubs	905
Number of Communities	14
Number of Nodes involved in Communities	375
Number of Links involved in Communities	631

Path Summary
Number Of Nodes in MetaPath	93
Number Of Links MetaPath	92
Number of Shortest Paths	3686079
Length Of Smallest Path	3
Average Path Length	27.8486
Length of Longest Path	48
Minimum Path Strength	1.41
Average Path Strength	6.01137
Maximum Path Strength	29.34
Minimum Path Correlation	0.7
Average Path Correlation	0.9912
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.125
Average % Of Corr. Nodes	41.4767
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	72.05
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• fibroblast proliferation • cell population proliferation • cellular process • cellular response to nitrogen compound • cellular response to stimulus • response to dopamine • regulation of cellular process • response to stimulus • signaling • cellular response to dopamine • response to monoamine • cell communication • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • signal transduction • regulation of biological process • G protein-coupled dopamine receptor signaling pathway • biological regulation • response to oxygen-containing compound • response to nitrogen compound • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex
Gene Ontology	Cellular Component	• cellular anatomical structure • membrane • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • plasma membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cell periphery • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell adhesion • regulation of cell adhesion • regulation of defense response • regulation of response to external stimulus • defense response • positive regulation of biological process • response to external stimulus • regulation of inflammatory response • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stimulus • regulation of response to stress • response to stress • positive regulation of defense response • inflammatory response • phospholipase C-activating G protein-coupled receptor signaling pathway • response to pH • cellular response to pH • response to abiotic stimulus • cellular response to acidic pH • response to acidic pH • cellular response to abiotic stimulus • cellular response to environmental stimulus • positive regulation of cell communication • small GTPase-mediated signal transduction • positive regulation of signal transduction • regulation of small GTPase mediated signal transduction • regulation of signal transduction • intracellular signal transduction • Rho protein signal transduction • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of cellular process • regulation of signaling • positive regulation of intracellular signal transduction • regulation of Rho protein signal transduction • positive regulation of Rho protein signal transduction • regulation of cell communication • positive regulation of small GTPase mediated signal transduction • positive regulation of signaling • regulation of vascular permeability • multicellular organismal process • system process • circulatory system process • vascular process in circulatory system • regulation of biological quality • blood circulation • cellular developmental process • connective tissue development • mesangial cell development • cell development • epithelial cell differentiation • renal system development • kidney vasculature development • multicellular organism development • pericyte cell differentiation • renal system vasculature development • mesangial cell differentiation • cell differentiation • anatomical structure development • nephron development • system development • epithelial cell differentiation involved in kidney development • blood vessel development • developmental process • epithelium development • animal organ development • tissue development • glomerular mesangium development • glomerular mesangial cell development • vasculature development • glomerular mesangial cell differentiation • circulatory system development • glomerulus development • epithelial cell development • cell differentiation involved in kidney development • glomerulus vasculature development • kidney development • regulation of developmental process • negative regulation of biological process • angiogenesis • regulation of vasculature development • tube morphogenesis • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • regulation of multicellular organismal development • blood vessel morphogenesis • tube development • negative regulation of blood vessel morphogenesis • negative regulation of developmental process • negative regulation of angiogenesis • negative regulation of vasculature development • anatomical structure morphogenesis • regulation of angiogenesis • anatomical structure formation involved in morphogenesis • negative regulation of multicellular organismal process • wound healing • angiogenesis involved in wound healing • response to wounding • protein binding • binding • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • cell population proliferation • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • response to oxygen-containing compound • cellular response to oxygen-containing compound • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to chemical stimulus • cellular response to alcohol • response to hormone • response to chemical • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • Ras protein signal transduction • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to nitrogen compound • cellular response to monoamine stimulus • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • molecular function regulator activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • hair follicle placode formation • ectodermal placode formation • skin development • skin epidermis development • hair follicle development • molting cycle • ectodermal placode development • hair cycle process • sensory perception of smell • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • skeletal system development • bone development • regulation of body fluid levels • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell-cell adhesion • coagulation • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • homeostatic process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of metabolic process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • negative regulation of inflammatory response • inflammatory response to antigenic stimulus • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8ZFC_Chain_A I E K Q L Q K D K Q V Y R A T H R L L L L G A S G K S T I V K Q M R I H V T S G I F E T K F Q V D K V N F H M F D V G Q R D E R R K W I Q C F N D V T A I I F V V S S Y N R L Q E A L N F K S I W N N R W L R T I S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C V D T E N R R F N D C R D I I Q R M H L R Q Y E L L T L S A E D K A A V E R S K M D N Y K A D D D S A I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8ZFC_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8ZFC_Chain_G Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F R Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	Q8BUD0
Sequence	>8ZFC_Chain_R V D S R V D H L F P P S L Y I F V I G V G L P T N C L A L W A A Y R Q V R Q H N E L G V Y L M N L S I A D L L Y I C T L P L W V D Y F L H H D N W I H G P G S C K L F G F I F Y S N I Y I S I A F L C C I S V D R Y L A V A H P L R F A R L R R V K T A V A V S S V V W A T E L G A N S A P L F H D E L F R D R Y N H T F C F E K F P M E R W V A W M N L Y R V F V G F L F P W A L M L L C Y R G I L R A V Q S S V S T E R Q E K V K I K R L A L S L I A I V L V C F A P Y H A L L L S R S A V Y L G R P W D C G F E E R V F S A Y H S S L A F T S L N C V A D P I L Y C L V N E G A R S D V A K A L H N L Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9JCP	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs-CtGq)/β1/γ2	2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCO	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCO (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	8ZD1	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZD1 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF4	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.05	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF7	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.15	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9 (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFB	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.78	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFD	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFE	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVH	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVM	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	2.36	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9BIP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BIP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	8ZCE	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCE (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFU	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	3.23	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi2-G13)/β1/γ2	3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZFZ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31 (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8Z3M	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2025-04-23	To be published
	8Z3M (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	To be published
	8Z3Q	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-04-23	To be published
	8Z3Q (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.76	2025-04-23	To be published
	8Z65	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-04-23	To be published
	8Z65 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.98	2025-04-23	To be published
	8Z66	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.06	2025-04-23	To be published
	8Z67	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-04-23	To be published
	9LMO	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-07-09	To be published
	9LMP	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	2.65	2025-07-02	To be published
	8Z3Y	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2025-06-04	To be published
	8Z3Y (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.2	2025-06-04	To be published
	8Z9P	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gi1/β1/γ2	2.5	2025-07-09	To be published
	8Z9P (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.5	2025-07-09	To be published
	9IV6	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.71	2025-07-30	To be published
	9IV6 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.71	2025-07-30	To be published
	8Z9O	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.4	2025-07-16	To be published
	8Z9O (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.4	2025-07-16	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8ZFC.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.