Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1A:A:H41 4.7025426
2A:A:L45 4.5575408
3A:A:S51 2.8475449
4A:A:K53 3.46449
5A:A:F212 4.5225409
6A:A:V214 3.715426
7A:A:V217 2.722525
8A:A:F219 5.012528
9A:A:H220 6.6375417
10A:A:F222 7.854517
11A:A:E230 8.0825419
12A:A:K233 4.97429719
13A:A:W234 4.965619
14A:A:F238 5.525619
15A:A:Y253 5.595408
16A:A:L270 4.464506
17A:A:F273 4.595409
18A:A:W277 6.464506
19A:A:W281 6.31415
20A:A:I288 3.95549
21A:A:F290 4.5475449
22A:A:L291 2.854568
23A:A:N292 4.328549
24A:A:Q294 4.2025466
25A:A:L297 3.7475468
26A:A:Y311 6.5025406
27A:A:F312 3.4065108
28A:A:F315 10.465406
29A:A:Y318 5.9475406
30A:A:Y339 4.105663
31A:A:F340 8.655107
32A:A:R342 4.41167664
33A:A:E344 5.98254105
34A:A:F345 4.816568
35A:A:S349 3.875407
36A:A:Y360 9.61167648
37A:A:F363 5.9565
38A:A:T364 4.7425449
39A:A:N371 4.245449
40A:A:R373 3.5775425
41A:A:R374 6.215444
42A:A:F376 2.63167628
43A:A:D381 6.5375448
44A:A:I383 3.94428
45A:A:R385 6.0925445
46A:A:H387 4.365428
47A:A:L388 4.87548
48A:A:Y391 5.612524
49B:B:L30 3.945405
50B:B:I37 2.945402
51B:B:I43 3.38403
52B:B:H54 8.1425409
53B:B:K57 7.95519
54B:B:Y59 7.702518
55B:B:M61 3.585456
56B:B:W63 4.16571757
57B:B:L70 4.6455
58B:B:I81 3.905417
59B:B:W82 8.578509
60B:B:S84 4.35455
61B:B:Y85 11.9225454
62B:B:N88 4.34754127
63B:B:K89 5.246509
64B:B:H91 4.645415
65B:B:I93 4.2225417
66B:B:L95 3.914518
67B:B:W99 7.50333619
68B:B:M101 3.3425419
69B:B:T102 2.8825418
70B:B:Y105 4.155406
71B:B:N110 5.49254114
72B:B:Y111 5.82754114
73B:B:C114 3.11667618
74B:B:G115 1.9419
75B:B:L117 2.905419
76B:B:N119 3.925409
77B:B:I123 3.1125406
78B:B:Y124 4.81714716
79B:B:E130 2.39403
80B:B:V133 3.565414
81B:B:L139 4.595409
82B:B:H142 6.182519
83B:B:Y145 5.515618
84B:B:L146 2.79517
85B:B:C148 2.834516
86B:B:C149 2.762518
87B:B:L152 4.96403
88B:B:S160 3.295416
89B:B:S161 7.805419
90B:B:D163 6.3675419
91B:B:C166 2.4125418
92B:B:W169 6.875618
93B:B:Q176 6.25414
94B:B:F180 5.97517
95B:B:H183 6.99833619
96B:B:D186 4.54619
97B:B:F199 5.932519
98B:B:V200 5.22416
99B:B:C204 4.73417
100B:B:D205 5.3175419
101B:B:K209 8.875416
102B:B:L210 4.84405
103B:B:W211 8.792518
104B:B:D212 5.3754159
105B:B:C218 4.12415
106B:B:F222 4.69418
107B:B:H225 7.46667619
108B:B:D228 7.755419
109B:B:I232 4.715418
110B:B:F235 5.90167616
111B:B:P236 4.8417
112B:B:F241 4.99571716
113B:B:T243 5.096518
114B:B:G244 2.7425415
115B:B:T249 4.585416
116B:B:C250 2.556518
117B:B:R251 8.896518
118B:B:F253 5.802516
119B:B:Y264 4.484515
120B:B:C271 3.885415
121B:B:I273 5.2325416
122B:B:T274 4.0325418
123B:B:V276 2.1625416
124B:B:F278 4.38333617
125B:B:Y289 5.80333617
126B:B:D290 5.49416
127B:B:N295 5.686516
128B:B:V296 3.44405
129B:B:W297 5.834518
130B:B:R304 6.6925415
131B:B:V307 2.6475413
132B:B:H311 7.316579
133B:B:R314 12.72418
134B:B:T321 5.075457
135B:B:T329 4.518578
136B:B:W332 10.1929719
137B:B:D333 9.975479
138B:B:L336 3.174507
139B:B:K337 5.3875476
140B:B:I338 3.3175455
141B:B:W339 5.66579
142G:G:V16 2.643336167
143G:G:L19 2.7625409
144G:G:E22 5.6375419
145G:G:D48 6.89409
146G:G:L51 5.2625406
147G:G:F61 4.38286758
148R:R:D16 8.305435
149R:R:P20 4.578535
150R:R:P21 4.2675437
151R:R:Y24 4.15571739
152R:R:V27 3.0725437
153R:R:W40 4.545484
154R:R:E51 5.9925427
155R:R:Y55 3.9825827
156R:R:M57 3.795405
157R:R:Y66 8.256537
158R:R:W73 9.07537
159R:R:F77 3.76333635
160R:R:D81 4.528534
161R:R:W83 5.88286739
162R:R:F97 12.89437
163R:R:Y102 6.3825407
164R:R:I103 4.028527
165R:R:F107 5.54667628
166R:R:C109 2.5175428
167R:R:I111 4.7975429
168R:R:S112 3.978529
169R:R:D114 4.305428
170R:R:R115 3.5675429
171R:R:Y116 4.288508
172R:R:L123 3.71426
173R:R:R129 3.96427
174R:R:W142 4.7025429
175R:R:P152 3.154183
176R:R:D161 6.62432
177R:R:Y163 7.61433
178R:R:H165 6.8375431
179R:R:F167 6.0825434
180R:R:F169 8.9154184
181R:R:E170 4.9875434
182R:R:F172 5.624535
183R:R:E175 6.1175492
184R:R:N182 6.148505
185R:R:Y201 3.35728
186R:R:S213 4.33443
187R:R:T214 4.9225443
188R:R:E218 5.6725445
189R:R:L229 4.6925428
190R:R:I232 2.7025427
191R:R:C236 2.73428
192R:R:F237 4.54714728
193R:R:Y240 5.67506
194R:R:H241 6.42428
195R:R:R247 10.02434
196R:R:R254 4.415402
197R:R:V264 5.1475404
198R:R:F265 7.48434
199R:R:Y268 9.49435
200R:R:H269 7.934535
201R:R:S276 4.458537
202R:R:C279 2.812539
203R:R:L285 3.0575428
204R:R:Y286 3.48629
205R:R:C287 2.422587
206R:R:D296 4.56484
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1A:A:C237 A:A:F238 73.79142.79NoYes189
2A:A:C237 B:B:M101 13.60223.24NoYes189
3B:B:G116 B:B:M101 16.75951.75NoYes099
4B:B:G115 B:B:G116 16.62492.11YesNo099
5A:A:F219 A:A:H41 23.78296.79YesYes286
6A:A:F212 A:A:F219 77.002410.72YesYes098
7A:A:F212 A:A:M221 1002.49YesNo098
8A:A:L45 A:A:M221 99.83315.65YesNo088
9A:A:K53 A:A:L45 97.32814.23YesYes098
10A:A:G47 A:A:K53 94.83943.49NoYes499
11A:A:G47 A:A:L46 96.01671.71NoNo098
12A:A:L44 A:A:L46 81.66994.15NoNo098
13A:A:F238 A:A:L44 81.41610.96YesNo099
14A:A:F219 A:A:V217 29.53152.62YesYes285
15A:A:F212 A:A:V214 23.88722.62YesYes096
16A:A:F376 A:A:V214 23.77725.24YesYes286
17A:A:F376 R:R:L123 47.49242.44YesYes286
18A:A:F219 A:A:F376 23.78322.14YesYes288
19A:A:H41 R:R:L123 23.75255.14YesYes266
20A:A:V217 R:R:L123 23.73722.98YesYes256
21A:A:I276 A:A:L46 14.37912.85NoNo088
22A:A:W281 B:B:W332 22.5761.87YesYes159
23B:B:W332 B:B:Y59 62.98037.72YesYes198
24A:A:D272 A:A:F246 19.53292.39NoNo089
25A:A:F246 A:A:F273 19.38575.36NoYes099
26A:A:F273 A:A:F345 11.4615.36YesYes098
27A:A:W281 B:B:D290 22.352.23YesYes156
28B:B:R314 B:B:W332 22.929326.99YesYes189
29B:B:D290 B:B:R314 22.337110.72YesYes168
30A:A:I383 R:R:L123 94.83494.28YesYes286
31A:A:H387 A:A:I383 94.19286.63YesYes288
32A:A:H387 R:R:A118 12.0964.39YesNo088
33A:A:H387 R:R:R129 82.01133.39YesYes287
34A:A:Y391 R:R:A118 11.93379.34YesNo048
35A:A:Y391 R:R:R129 11.92993.09YesYes247
36R:R:D114 R:R:R129 25.35042.38YesYes287
37A:A:Y391 R:R:R115 20.43082.06YesYes249
38B:B:G115 B:B:T102 10.72851.82YesYes198
39B:B:C148 B:B:T102 10.4843.38YesYes168
40B:B:I37 B:B:L300 11.71942.85YesNo026
41B:B:I37 B:B:T34 10.43394.56YesNo025
42B:B:S316 B:B:W332 18.14594.94NoYes099
43B:B:C317 B:B:S316 18.02161.72NoNo079
44B:B:C271 B:B:D290 44.70934.67YesYes156
45B:B:C271 B:B:Y289 43.98732.69YesYes157
46B:B:I273 B:B:Y289 25.665810.88YesYes167
47B:B:G244 B:B:I273 24.20263.53YesYes156
48B:B:G244 B:B:T243 23.49523.64YesYes158
49B:B:F241 B:B:T243 10.53462.59YesYes168
50B:B:W297 B:B:Y289 15.7544.82YesYes187
51B:B:L285 B:B:W297 13.89212.28NoYes168
52B:B:F278 B:B:L285 13.74696.09YesNo176
53R:R:E51 R:R:R129 44.5856.98YesYes277
54R:R:E51 R:R:Y55 25.18763.37YesYes277
55R:R:V54 R:R:Y55 38.48997.57NoYes277
56R:R:M57 R:R:V54 57.03533.04YesNo057
57R:R:L39 R:R:M57 55.62942.83NoYes075
58R:R:I61 R:R:L39 44.10411.43NoNo057
59R:R:I61 R:R:L65 43.58071.43NoNo057
60R:R:I96 R:R:L65 43.05815.71NoNo057
61R:R:I96 R:R:T69 21.31979.12NoNo057
62R:R:T69 R:R:W73 16.56472.43NoYes077
63R:R:D114 R:R:Y55 25.25113.45YesYes287
64R:R:A134 R:R:E51 19.23884.53NoYes287
65R:R:A134 R:R:V54 19.06923.39NoNo287
66R:R:I96 R:R:N100 21.22435.66NoNo058
67R:R:N100 R:R:Y66 20.70179.3NoYes087
68R:R:C279 R:R:Y66 10.15492.69YesYes397
69R:R:L39 R:R:S60 11.39094.5NoNo078
70R:R:A38 R:R:S60 10.84931.71NoNo098
71R:R:A38 R:R:C287 10.30773.61NoYes097
72R:R:R115 R:R:Y286 19.29212.06YesYes299
73R:R:D282 R:R:Y286 16.64712.3NoYes099
74R:R:D282 R:R:N278 15.64519.42NoNo099
75R:R:F237 R:R:N278 14.940510.87YesNo289
76R:R:F237 R:R:H241 14.52652.26YesYes288
77R:R:H241 R:R:Y102 12.97655.44YesYes087
78R:R:R185 R:R:Y102 12.212112.35NoYes057
79A:A:C237 B:B:Y59 60.11345.38NoYes188
80B:B:C317 B:B:M61 10.19164.86NoYes076
81A:A:D272 A:A:I276 13.13452.8NoNo188
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 9IV6
Class A
SubFamily Orphan
Type Orphan
SubType GPR4
Species Homo Sapiens
Ligand -
Other Ligand(s) -
Protein Partners chim(NtGi1-Gs)/Beta1/Gamma2
PDB Resolution 2.71
Date 2025-07-30
D.O.I. To be published
Net Summary
Imin 1.71
Number of Linked Nodes 864
Number of Links 1103
Number of Hubs 206
Number of Links mediated by Hubs 708
Number of Communities 18
Number of Nodes involved in Communities 285
Number of Links involved in Communities 436
Path Summary
Number Of Nodes in MetaPath 82
Number Of Links MetaPath 81
Number of Shortest Paths 2938953
Length Of Smallest Path 3
Average Path Length 31.0183
Length of Longest Path 54
Minimum Path Strength 1.315
Average Path Strength 4.84046
Maximum Path Strength 22.195
Minimum Path Correlation 0.7
Average Path Correlation 0.988689
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 2.85714
Average % Of Corr. Nodes 38.2654
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 59.1761
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • adenylate cyclase-activating G protein-coupled receptor signaling pathway   • cell communication   • adenylate cyclase-modulating G protein-coupled receptor signaling pathway   • G protein-coupled receptor signaling pathway   • cellular process   • signal transduction   • cell adhesion   • regulation of cell adhesion   • regulation of defense response   • regulation of response to external stimulus   • defense response   • positive regulation of biological process   • response to external stimulus   • regulation of inflammatory response   • positive regulation of response to stimulus   • positive regulation of response to external stimulus   • positive regulation of inflammatory response   • regulation of response to stimulus   • regulation of response to stress   • response to stress   • positive regulation of defense response   • inflammatory response   • phospholipase C-activating G protein-coupled receptor signaling pathway   • positive regulation of cell communication   • small GTPase-mediated signal transduction   • positive regulation of signal transduction   • regulation of small GTPase mediated signal transduction   • regulation of signal transduction   • intracellular signal transduction   • Rho protein signal transduction   • regulation of intracellular signal transduction   • intracellular signaling cassette   • positive regulation of cellular process   • regulation of signaling   • positive regulation of intracellular signal transduction   • regulation of Rho protein signal transduction   • positive regulation of Rho protein signal transduction   • regulation of cell communication   • positive regulation of small GTPase mediated signal transduction   • positive regulation of signaling   • regulation of vascular permeability   • multicellular organismal process   • system process   • circulatory system process   • vascular process in circulatory system   • regulation of biological quality   • blood circulation   • cellular developmental process   • connective tissue development   • mesangial cell development   • cell development   • epithelial cell differentiation   • renal system development   • kidney vasculature development   • multicellular organism development   • pericyte cell differentiation   • renal system vasculature development   • mesangial cell differentiation   • cell differentiation   • anatomical structure development   • nephron development   • system development   • epithelial cell differentiation involved in kidney development   • blood vessel development   • developmental process   • epithelium development   • animal organ development   • tissue development   • glomerular mesangium development   • glomerular mesangial cell development   • vasculature development   • glomerular mesangial cell differentiation   • circulatory system development   • glomerulus development   • epithelial cell development   • cell differentiation involved in kidney development   • glomerulus vasculature development   • kidney development   • regulation of developmental process   • negative regulation of biological process   • angiogenesis   • regulation of vasculature development   • tube morphogenesis   • regulation of multicellular organismal process   • regulation of anatomical structure morphogenesis   • regulation of multicellular organismal development   • blood vessel morphogenesis   • tube development   • negative regulation of blood vessel morphogenesis   • negative regulation of developmental process   • negative regulation of angiogenesis   • negative regulation of vasculature development   • anatomical structure morphogenesis   • regulation of angiogenesis   • anatomical structure formation involved in morphogenesis   • negative regulation of multicellular organismal process   • response to pH   • response to abiotic stimulus   • response to acidic pH   • wound healing   • angiogenesis involved in wound healing   • response to wounding   • cell periphery   • cellular anatomical structure   • plasma membrane   • membrane   • protein binding   • binding   • enzyme binding   • GTPase binding   • protein-containing complex binding   • pyrophosphatase activity   • GTPase activity   • ribonucleoside triphosphate phosphatase activity   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • hydrolase activity   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • signaling receptor complex adaptor activity   • protein-macromolecule adaptor activity   • molecular adaptor activity   • signaling adaptor activity   • sensory perception of chemical stimulus   • sensory perception   • nervous system process   • sensory perception of taste   • sensory organ development   • eye development   • retina development in camera-type eye   • visual system development   • camera-type eye development   • sensory system development   • cell population proliferation   • response to ketone   • response to prostaglandin   • response to lipid   • response to endogenous stimulus   • response to alcohol   • cellular response to prostaglandin stimulus   • response to oxygen-containing compound   • cellular response to oxygen-containing compound   • cellular response to endogenous stimulus   • cellular response to prostaglandin E stimulus   • cellular response to chemical stimulus   • cellular response to alcohol   • response to hormone   • response to chemical   • cellular response to lipid   • response to prostaglandin E   • cellular response to ketone   • cellular response to hormone stimulus   • Ras protein signal transduction   • cellular response to nitrogen compound   • response to dopamine   • cellular response to dopamine   • response to monoamine   • response to catecholamine   • adenylate cyclase-activating dopamine receptor signaling pathway   • cellular response to catecholamine stimulus   • G protein-coupled dopamine receptor signaling pathway   • response to nitrogen compound   • cellular response to monoamine stimulus   • synaptic signaling   • cellular response to acetylcholine   • cell-cell signaling   • acetylcholine receptor signaling pathway   • postsynaptic signal transduction   • G protein-coupled acetylcholine receptor signaling pathway   • response to acetylcholine   • protein-containing complex   • extrinsic component of plasma membrane   • catalytic complex   • plasma membrane protein complex   • cytoplasmic side of membrane   • membrane protein complex   • heterotrimeric G-protein complex   • side of membrane   • cytoplasmic side of plasma membrane   • GTPase complex   • extrinsic component of membrane   • extrinsic component of cytoplasmic side of plasma membrane   • extracellular exosome   • membrane-bounded organelle   • extracellular vesicle   • extracellular organelle   • extracellular region   • organelle   • extracellular space   • vesicle   • extracellular membrane-bounded organelle   • non-motile cilium   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • photoreceptor cell cilium   • organelle membrane   • intracellular anatomical structure   • cytoplasm   • cytosol   • vacuolar membrane   • lytic vacuole   • vacuole   • intracellular membrane-bounded organelle   • intracellular organelle   • lytic vacuole membrane   • bounding membrane of organelle   • lysosomal membrane   • lysosome   • synapse   • cell junction   • G-protein beta-subunit binding   • fibroblast proliferation
Gene OntologyCellular Component
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainA
ProteinG Protein α Sub unit
UniProtP63092
Sequence
>9IV6_Chain_A
EKAEKIEKQ LQKDKQVYR ATHRLLLLG ASGKSTIVK QMRIHVVTS 
GIFETKFQV DKVNFHMFD VGQRDERRK WIQCFNDVT AIIFVVSSY 
NRLQEALNF KSIWNNRWL RTISVILFL NKQDLLAEK VLAGKSKIE 
DYFPEFARY TTPEDATPE PGEDPRVTR AKYFIRDEF LRISTASGD 
GRHYCYPHF TCVDTENRR FNDCRDIIQ RMHLRQYEL LTLSADAVR 
SMDNYKADD DSAI


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainB
ProteinG Protein β Sub unit
UniProtP62873
Sequence
>9IV6_Chain_B
LRQEAEQLK NQIRDARKA CADATLSQI TNNIDPVGR IQMRTRRTL 
RGHLAKIYA MHWGTDSRL LVSASQDGK LIIWDSYTT NKVHAIPLR 
SSWVMTCAY APSGNYVAC GGLDNICSI YNLKTREGN VRVSRELAG 
HTGYLSCCR FLDDNQIVT SSGDTTCAL WDIETGQQT TTFTGHTGD 
VMSLSLAPD TRLFVSGAC DASAKLWDV REGMCRQTF TGHESDINA 
ICFFPNGNA FATGSDDAT CRLFDLRAD QELMTYSHD NIICGITSV 
SFSKSGRLL LAGYDDFNC NVWDALKAD RAGVLAGHD NRVSCLGVT 
DDGMAVATG SWDSFLKIW N


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainG
ProteinG Protein γ Sub unit
UniProtP59768
Sequence
>9IV6_Chain_G
RKLVEQLKM EANIDRIKV SKAAADLMA YCEAHAKED PLLTPVPAS 
ENPFR


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtP46093
Sequence
>9IV6_Chain_R
GCHVDSRVD HLFPPSLYI FVIGVGLPT NCLALWAAY RQVQQRNEL 
GVYLMNLSI ADLLYICTL PLWVDYFLH HDNWIHGPG SCKLFGFIF 
YTNIYISIA FLCCISVDR YLAVAHPLR FARLRRVKT AVAVSSVVW 
ATELGANSA PLFHDELFR DRYNHTFCF EKFPMEGWV AWMNLYRVF 
VGFLFPWAL MLLSYRGIL RAVRGSVST ERQEKAKIK RLALSLIAI 
VLVCFAPYH VLLLSRSAI YLGRPWDCG FEERVFSAY HSSLAFTSL 
NCVADPILY CLVNEGARS DVAKALHNL


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
9JCPAOrphanOrphanGPR4Homo sapiens-LPCchim(NtGi1-Gs-CtGq)/β1/γ22.552025-07-09doi.org/10.1038/s41421-025-00807-y
9JCP (No Gprot) AOrphanOrphanGPR4Homo sapiens-LPC2.552025-07-09doi.org/10.1038/s41421-025-00807-y
9JCOAOrphanOrphanGPR4Homo sapiens-LPCchim(NtGi1-Gs)/β1/γ22.362025-07-09doi.org/10.1038/s41421-025-00807-y
9JCO (No Gprot) AOrphanOrphanGPR4Homo sapiens-LPC2.362025-07-09doi.org/10.1038/s41421-025-00807-y
9JCQAOrphanOrphanGPR4Homo sapiens-LPCchim(NtGi1-Gs)/β1/γ22.592025-07-09doi.org/10.1038/s41421-025-00807-y
9JCQ (No Gprot) AOrphanOrphanGPR4Homo sapiens-LPC2.592025-07-09doi.org/10.1038/s41421-025-00807-y
8ZD1AOrphanOrphanGPR4Xenopus tropicalis--chim(NtGi1-Gs)/β1/γ22.62025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZD1 (No Gprot) AOrphanOrphanGPR4Xenopus tropicalis--2.62025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZF4AOrphanOrphanGPR4Xenopus tropicalis---3.052025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZF6AOrphanOrphanGPR4Xenopus tropicalis--chim(NtGi1-Gs)/β1/γ22.982025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZF6 (No Gprot) AOrphanOrphanGPR4Xenopus tropicalis--2.982025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZF7AOrphanOrphanGPR4Xenopus tropicalis---3.152025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZF9AOrphanOrphanGPR4Mus musculus--chim(NtGi1-Gs)/β1/γ22.562025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZF9 (No Gprot) AOrphanOrphanGPR4Mus musculus--2.562025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZFAAOrphanOrphanGPR4Xenopus tropicalis--chim(NtGi1-Gs)/β1/γ22.962025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZFA (No Gprot) AOrphanOrphanGPR4Xenopus tropicalis--2.962025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZFBAOrphanOrphanGPR4Xenopus tropicalis---3.782025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZFCAOrphanOrphanGPR4Mus musculus--chim(NtGi1-Gs)/β1/γ22.682025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZFC (No Gprot) AOrphanOrphanGPR4Mus musculus--2.682025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZFDAOrphanOrphanGPR4Mus musculus---2.562025-02-26doi.org/10.1016/j.cell.2024.12.001
8ZFEAOrphanOrphanGPR4Mus musculus---2.562025-02-26doi.org/10.1016/j.cell.2024.12.001
9JVGAOrphanOrphanGPR4Mus musculus--chim(NtGi1-Gs)/β1/γ22.762025-02-26doi.org/10.1016/j.cell.2024.12.001
9JVG (No Gprot) AOrphanOrphanGPR4Mus musculus--2.762025-02-26doi.org/10.1016/j.cell.2024.12.001
9JVHAOrphanOrphanGPR4Mus musculus---2.762025-02-26doi.org/10.1016/j.cell.2024.12.001
9JVMAOrphanOrphanGPR4Xenopus tropicalis---2.362025-02-26doi.org/10.1016/j.cell.2024.12.001
9BIPAOrphanOrphanGPR4Homo sapiens--Gs/β1/γ22.82025-01-22doi.org/10.1016/j.cell.2024.11.036
9BIP (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.82025-01-22doi.org/10.1016/j.cell.2024.11.036
8ZCEAOrphanOrphanGPR4Homo sapiens--Gs/β1/γ23.12025-04-23doi.org/10.1038/s41422-025-01092-w
8ZCE (No Gprot) AOrphanOrphanGPR4Homo sapiens--3.12025-04-23doi.org/10.1038/s41422-025-01092-w
8ZCFAOrphanOrphanGPR4Homo sapiens--Gs/β1/γ22.92025-04-23doi.org/10.1038/s41422-025-01092-w
8ZCF (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.92025-04-23doi.org/10.1038/s41422-025-01092-w
9JFUAOrphanOrphanGPR4Homo sapiensNE52-QQ57--3.232025-04-23doi.org/10.1038/s41422-025-01092-w
9JFVAOrphanOrphanGPR4Homo sapiens--chim(Gs-CtGq)/β1/γ22.672025-04-23doi.org/10.1038/s41422-025-01092-w
9JFV (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.672025-04-23doi.org/10.1038/s41422-025-01092-w
9JFWAOrphanOrphanGPR4Homo sapiens--Gs/β1/γ23.132025-04-23doi.org/10.1038/s41422-025-01092-w
9JFW (No Gprot) AOrphanOrphanGPR4Homo sapiens--3.132025-04-23doi.org/10.1038/s41422-025-01092-w
9JFXAOrphanOrphanGPR4Homo sapiens--chim(Gs-CtGq)/β1/γ22.872025-04-23doi.org/10.1038/s41422-025-01092-w
9JFX (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.872025-04-23doi.org/10.1038/s41422-025-01092-w
9JFZAOrphanOrphanGPR4Homo sapiens--chim(Gs-CtGq)/β1/γ22.92025-04-23doi.org/10.1038/s41422-025-01092-w
9JFZ (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.92025-04-23doi.org/10.1038/s41422-025-01092-w
9JHPAOrphanOrphanGPR4Homo sapiens--chim(NtGi2-G13)/β1/γ23.352025-04-23doi.org/10.1038/s41422-025-01092-w
9JHP (No Gprot) AOrphanOrphanGPR4Homo sapiens--3.352025-04-23doi.org/10.1038/s41422-025-01092-w
9LGMAOrphanOrphanGPR4Homo sapiens--Gs/β1/γ22.842025-04-23doi.org/10.1038/s41422-025-01092-w
9LGM (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.842025-04-23doi.org/10.1038/s41422-025-01092-w
8ZFZAOrphanOrphanGPR4Danio rerio--chim(NtGi1-Gs)/β1/γ23.32025-01-22doi.org/10.1038/s41467-025-55901-2
8ZFZ (No Gprot) AOrphanOrphanGPR4Danio rerio--3.32025-01-22doi.org/10.1038/s41467-025-55901-2
9J31AOrphanOrphanGPR4Danio rerio--chim(NtGi1-Gs)/β1/γ23.052025-01-22doi.org/10.1038/s41467-025-55901-2
9J31 (No Gprot) AOrphanOrphanGPR4Danio rerio--3.052025-01-22doi.org/10.1038/s41467-025-55901-2
8Z3MAOrphanOrphanGPR4Homo sapiens--chim(NtGi1-Gs-CtGq)/β1/γ22.92025-04-23To be published
8Z3M (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.92025-04-23To be published
8Z3QAOrphanOrphanGPR4Homo sapiens--chim(NtGi1-Gs)/β1/γ22.762025-04-23To be published
8Z3Q (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.762025-04-23To be published
8Z65AOrphanOrphanGPR4Homo sapiens--chim(NtGi1-Gs)/β1/γ22.982025-04-23To be published
8Z65 (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.982025-04-23To be published
8Z66AOrphanOrphanGPR4Homo sapiens---3.062025-04-23To be published
8Z67AOrphanOrphanGPR4Homo sapiens---3.22025-04-23To be published
9LMOAOrphanOrphanGPR4Homo sapiens---3.22025-07-09To be published
9LMPAOrphanOrphanGPR4Homo sapiensNE52-QQ57--2.652025-07-02To be published
8Z3YAOrphanOrphanGPR4Homo sapiens--chim(NtGi1-Gs)/β1/γ23.22025-06-04To be published
8Z3Y (No Gprot) AOrphanOrphanGPR4Homo sapiens--3.22025-06-04To be published
8Z9PAOrphanOrphanGPR4Homo sapiens--Gi1/β1/γ22.52025-07-09To be published
8Z9P (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.52025-07-09To be published
9IV6AOrphanOrphanGPR4Homo sapiens--chim(NtGi1-Gs)/β1/γ22.712025-07-30To be published
9IV6 (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.712025-07-30To be published
8Z9OAOrphanOrphanGPR4Homo sapiens--Gs/β1/γ22.42025-07-16To be published
8Z9O (No Gprot) AOrphanOrphanGPR4Homo sapiens--2.42025-07-16To be published




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9IV6.zip



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