psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	A:A:E15	A:A:Q12	6.37	No	No	0	6	2
2	A:A:E16	A:A:Q12	2.55	No	No	0	4	2
3	A:A:E15	A:A:Q19	3.82	No	Yes	0	6	4
4	A:A:E16	A:A:K17	4.05	No	No	0	4	4
5	A:A:Q19	B:B:D83	9.14	Yes	No	3	4	8
6	A:A:Q19	B:B:T86	5.67	Yes	No	3	4	6
7	A:A:Q19	B:B:N88	7.92	Yes	No	3	4	7
8	A:A:K24	A:A:R20	2.48	No	No	0	4	3
9	A:A:A22	A:A:E21	3.02	No	No	0	4	2
10	A:A:E21	A:A:K25	10.8	No	No	0	2	5
11	A:A:E27	A:A:N23	2.63	No	No	3	6	7
12	A:A:N23	B:B:N88	13.62	No	No	3	7	7
13	A:A:N23	B:B:K89	5.6	No	Yes	3	7	9
14	A:A:I26	B:B:K89	7.27	No	Yes	0	9	9
15	A:A:I26	B:B:A92	3.25	No	No	0	9	6
16	A:A:E27	A:A:L30	3.98	No	No	3	6	5
17	A:A:E27	B:B:K89	13.5	No	Yes	3	6	9
18	A:A:K28	A:A:K32	5.75	No	No	0	4	4
19	A:A:D33	A:A:Q29	11.75	No	No	0	5	4
20	A:A:L30	B:B:I80	4.28	No	Yes	3	5	8
21	A:A:L30	B:B:K89	2.82	No	Yes	3	5	9
22	A:A:K34	A:A:Q31	4.07	No	No	0	4	4
23	A:A:Q31	A:A:Q35	6.4	No	No	0	4	3
24	A:A:D33	B:B:K78	11.06	No	No	0	5	8
25	A:A:K34	B:B:L55	5.64	No	No	0	4	6
26	A:A:K34	R:R:R49	4.95	No	No	0	4	6
27	A:A:R42	A:A:Y37	23.66	Yes	Yes	0	9	4
28	A:A:Y37	B:B:L55	5.86	Yes	No	13	4	6
29	A:A:Y37	B:B:A56	4	Yes	No	13	4	7
30	A:A:Y37	B:B:D76	3.45	Yes	Yes	13	4	9
31	A:A:R42	A:A:T40	5.17	Yes	No	0	9	7
32	A:A:N218	A:A:T40	5.85	No	No	0	4	7
33	A:A:H41	A:A:V217	2.77	Yes	No	1	6	5
34	A:A:F219	A:A:H41	3.39	Yes	Yes	1	8	6
35	A:A:H41	A:A:T242	4.11	Yes	Yes	1	6	8
36	A:A:H41	A:A:I383	5.3	Yes	Yes	1	6	8
37	A:A:H41	R:R:L123	5.14	Yes	Yes	1	6	6
38	A:A:F222	A:A:R42	5.34	Yes	Yes	0	7	9
39	A:A:R42	A:A:V241	2.62	Yes	No	0	9	9
40	A:A:F219	A:A:L43	3.65	Yes	No	1	8	7
41	A:A:I245	A:A:L43	2.85	Yes	No	1	7	7
42	A:A:L43	A:A:V375	4.47	No	Yes	1	7	9
43	A:A:F238	A:A:L44	21.92	Yes	No	0	9	9
44	A:A:I244	A:A:L44	4.28	No	No	0	8	9
45	A:A:I56	A:A:L45	5.71	Yes	No	0	7	8
46	A:A:L45	A:A:M221	5.65	No	Yes	0	8	8
47	A:A:I245	A:A:L45	2.85	Yes	No	0	7	8
48	A:A:I56	A:A:K53	2.91	Yes	No	1	7	9
49	A:A:K53	A:A:V247	6.07	No	No	1	9	7
50	A:A:K53	A:A:N292	8.39	No	Yes	1	9	9
51	A:A:N54	A:A:V57	4.43	No	No	0	9	7
52	A:A:K58	A:A:T55	9.01	No	No	0	9	9
53	A:A:Q59	A:A:T55	4.25	No	No	0	9	9
54	A:A:I56	A:A:M60	2.92	Yes	Yes	1	7	9
55	A:A:I56	A:A:V247	7.68	Yes	No	1	7	7
56	A:A:D223	A:A:V57	4.38	No	No	0	9	7
57	A:A:Q59	A:A:T369	4.25	No	No	0	9	9
58	A:A:F212	A:A:M60	3.73	Yes	Yes	1	9	9
59	A:A:M221	A:A:M60	5.78	Yes	Yes	1	8	9
60	A:A:I372	A:A:M60	4.37	No	Yes	0	8	9
61	A:A:F208	A:A:S205	3.96	No	No	0	5	7
62	A:A:G206	B:B:N119	6.79	No	No	0	8	9
63	A:A:E209	A:A:I207	10.93	No	Yes	2	9	9
64	A:A:F222	A:A:I207	5.02	Yes	Yes	2	7	9
65	A:A:F238	A:A:I207	2.51	Yes	Yes	2	9	9
66	A:A:I207	B:B:W99	4.7	Yes	Yes	2	9	9
67	A:A:I207	B:B:L117	4.28	Yes	Yes	2	9	9
68	A:A:D223	A:A:F208	2.39	No	No	0	9	5
69	A:A:F208	A:A:G225	3.01	No	No	0	5	9
70	A:A:E209	A:A:H220	6.15	No	No	2	9	7
71	A:A:E209	A:A:F222	7	No	Yes	2	9	7
72	A:A:M221	A:A:T210	3.01	Yes	No	0	8	7
73	A:A:H220	A:A:K211	6.55	No	No	0	7	4
74	A:A:F212	A:A:F219	11.79	Yes	Yes	1	9	8
75	A:A:F212	A:A:M221	4.98	Yes	Yes	1	9	8
76	A:A:N218	A:A:Q213	10.56	No	No	0	4	3
77	A:A:D215	A:A:V214	5.84	No	Yes	1	5	6
78	A:A:I372	A:A:V214	4.61	No	Yes	0	8	6
79	A:A:R373	A:A:V214	2.62	No	Yes	1	5	6
80	A:A:F376	A:A:V214	9.18	Yes	Yes	1	8	6
81	A:A:D215	A:A:R373	4.76	No	No	1	5	5
82	A:A:D215	A:A:F376	8.36	No	Yes	1	5	8
83	A:A:F219	A:A:V217	3.93	Yes	No	1	8	5
84	A:A:V217	R:R:L123	4.47	No	Yes	1	5	6
85	A:A:F219	A:A:F376	4.29	Yes	Yes	1	8	8
86	A:A:C379	A:A:F219	5.59	No	Yes	0	8	8
87	A:A:F222	A:A:H220	18.1	Yes	No	2	7	7
88	A:A:F222	A:A:F238	3.22	Yes	Yes	2	7	9
89	A:A:F222	B:B:W99	23.05	Yes	Yes	2	7	9
90	A:A:Q227	A:A:V224	2.87	Yes	Yes	0	9	9
91	A:A:V224	A:A:W234	11.03	Yes	Yes	0	9	9
92	A:A:F238	A:A:V224	2.62	Yes	Yes	0	9	9
93	A:A:Q227	B:B:L117	5.32	Yes	Yes	0	9	9
94	A:A:Q227	B:B:N119	3.96	Yes	No	0	9	9
95	A:A:Q227	B:B:Y145	11.27	Yes	Yes	0	9	8
96	A:A:D229	A:A:R228	2.38	No	Yes	2	8	9
97	A:A:E230	A:A:R228	15.12	No	Yes	2	9	9
98	A:A:R228	B:B:T164	6.47	Yes	No	0	9	6
99	A:A:R228	B:B:D186	9.53	Yes	Yes	2	9	9
100	A:A:D229	A:A:E230	2.6	No	No	2	8	9
101	A:A:E230	A:A:R232	9.3	No	No	2	9	8
102	A:A:R231	A:A:W234	8	No	Yes	0	9	9
103	A:A:L272	A:A:R231	10.93	No	No	0	8	9
104	A:A:K233	A:A:R232	7.43	Yes	No	2	9	8
105	A:A:R232	B:B:D228	11.91	No	Yes	2	8	9
106	A:A:K233	A:A:Q236	9.49	Yes	No	2	9	8
107	A:A:K233	B:B:M188	5.76	Yes	Yes	2	9	8
108	A:A:K233	B:B:D228	6.91	Yes	Yes	2	9	9
109	A:A:K233	B:B:N230	8.39	Yes	No	2	9	9
110	A:A:K233	B:B:D246	6.91	Yes	No	2	9	9
111	A:A:I235	A:A:W234	3.52	No	Yes	0	9	9
112	A:A:W234	B:B:Y145	2.89	Yes	Yes	0	9	8
113	A:A:I235	A:A:L282	2.85	No	Yes	0	9	9
114	A:A:Q236	A:A:W281	9.86	No	Yes	2	8	5
115	A:A:Q236	B:B:R314	5.84	No	Yes	2	8	8
116	A:A:C237	A:A:F238	2.79	Yes	Yes	2	8	9
117	A:A:C237	B:B:Y59	4.03	Yes	Yes	2	8	8
118	A:A:C237	B:B:W99	2.61	Yes	Yes	2	8	9
119	A:A:C237	B:B:M101	3.24	Yes	Yes	2	8	9
120	A:A:F238	A:A:V241	3.93	Yes	No	0	9	9
121	A:A:F238	B:B:W99	12.03	Yes	Yes	2	9	9
122	A:A:F238	B:B:L117	2.44	Yes	Yes	2	9	9
123	A:A:D240	A:A:N239	13.46	No	No	2	6	8
124	A:A:N239	B:B:K57	6.99	No	Yes	2	8	9
125	A:A:N239	B:B:W332	11.3	No	Yes	2	8	9
126	A:A:D240	B:B:K57	11.06	No	Yes	2	6	9
127	A:A:C379	A:A:T242	5.07	No	Yes	0	8	8
128	A:A:I382	A:A:T242	4.56	Yes	Yes	1	6	8
129	A:A:I383	A:A:T242	3.04	Yes	Yes	1	8	8
130	A:A:A243	A:A:I288	3.25	No	Yes	0	8	9
131	A:A:I244	A:A:L282	4.28	No	Yes	15	8	9
132	A:A:I244	A:A:T285	3.04	No	No	15	8	7
133	A:A:F290	A:A:I245	2.51	Yes	Yes	1	9	7
134	A:A:I245	A:A:V375	6.14	Yes	Yes	1	7	9
135	A:A:F246	A:A:L272	7.31	No	No	0	9	8
136	A:A:F246	A:A:F273	3.22	No	Yes	0	9	9
137	A:A:F246	A:A:I276	2.51	No	No	0	9	8
138	A:A:N292	A:A:V247	4.43	Yes	No	1	9	7
139	A:A:L291	A:A:V248	5.96	Yes	No	0	8	7
140	A:A:F345	A:A:V248	7.87	Yes	No	0	8	7
141	A:A:A249	A:A:R265	4.15	No	No	1	8	9
142	A:A:A249	A:A:K293	3.21	No	Yes	1	8	9
143	A:A:L291	A:A:S250	3	Yes	No	0	8	6
144	A:A:L297	A:A:S250	3	No	No	0	8	6
145	A:A:L266	A:A:S251	3	Yes	No	9	8	9
146	A:A:K307	A:A:S251	10.71	Yes	No	9	6	9
147	A:A:L266	A:A:N264	6.87	Yes	Yes	9	8	9
148	A:A:N264	A:A:Q267	7.92	Yes	No	9	9	4
149	A:A:K307	A:A:N264	12.59	Yes	Yes	9	6	9
150	A:A:N264	A:A:Y311	9.3	Yes	No	9	9	6
151	A:A:F312	A:A:N264	3.62	Yes	Yes	9	8	9
152	A:A:K293	A:A:R265	4.95	Yes	No	1	9	9
153	A:A:K307	A:A:L266	4.23	Yes	Yes	9	6	8
154	A:A:F312	A:A:L266	3.65	Yes	Yes	9	8	8
155	A:A:I341	A:A:L266	2.85	No	Yes	0	8	8
156	A:A:K271	A:A:Q267	6.78	No	No	0	5	4
157	A:A:F312	A:A:Q267	14.05	Yes	No	9	8	4
158	A:A:F345	A:A:L270	7.31	Yes	No	0	8	6
159	A:A:L272	A:A:S275	3	No	No	0	8	8
160	A:A:F273	A:A:W277	4.01	Yes	Yes	8	9	6
161	A:A:F273	A:A:V287	2.62	Yes	No	8	9	6
162	A:A:F273	A:A:F345	7.5	Yes	Yes	0	9	8
163	A:A:F273	A:A:I348	10.05	Yes	No	0	9	4
164	A:A:F273	A:A:S349	2.64	Yes	Yes	8	9	7
165	A:A:C359	A:A:F273	5.59	Yes	Yes	8	5	9
166	A:A:D274	A:A:N278	4.04	No	No	0	5	8
167	A:A:D274	A:A:I348	12.59	No	No	0	5	4
168	A:A:I276	A:A:L282	5.71	No	Yes	0	8	9
169	A:A:V287	A:A:W277	4.9	No	Yes	8	6	6
170	A:A:S349	A:A:W277	4.94	Yes	Yes	8	7	6
171	A:A:H357	A:A:W277	34.91	No	Yes	0	7	6
172	A:A:C359	A:A:W277	5.22	Yes	Yes	8	5	6
173	A:A:N278	A:A:S352	2.98	No	No	0	8	5
174	A:A:L282	A:A:N279	12.36	Yes	No	0	9	8
175	A:A:K280	A:A:W281	24.37	No	Yes	2	5	5
176	A:A:K280	B:B:D290	5.53	No	Yes	2	5	6
177	A:A:W281	B:B:D290	8.93	Yes	Yes	2	5	6
178	A:A:W281	B:B:R314	15.99	Yes	Yes	2	5	8
179	A:A:W281	B:B:W332	4.69	Yes	Yes	2	5	9
180	A:A:L282	A:A:T285	7.37	Yes	No	15	9	7
181	A:A:D284	A:A:R283	5.96	No	No	16	4	3
182	A:A:R283	A:A:R356	3.2	No	Yes	16	3	2
183	A:A:D284	A:A:R356	4.76	No	Yes	16	4	2
184	A:A:S286	A:A:Y360	6.36	No	Yes	1	8	8
185	A:A:I382	A:A:S286	6.19	Yes	No	1	6	8
186	A:A:F290	A:A:I288	5.02	Yes	Yes	1	9	9
187	A:A:H362	A:A:I288	2.65	Yes	Yes	1	9	9
188	A:A:I288	A:A:V375	4.61	Yes	Yes	1	9	9
189	A:A:D378	A:A:I288	12.59	No	Yes	1	7	9
190	A:A:L289	A:A:L291	4.15	No	Yes	0	9	8
191	A:A:F345	A:A:L289	6.09	Yes	No	0	8	9
192	A:A:C359	A:A:L289	3.17	Yes	No	0	5	9
193	A:A:F290	A:A:T364	3.89	Yes	No	0	9	9
194	A:A:F290	A:A:N371	13.29	Yes	No	1	9	9
195	A:A:F290	A:A:R374	5.34	Yes	Yes	1	9	4
196	A:A:F290	A:A:V375	2.62	Yes	Yes	1	9	9
197	A:A:F363	A:A:L291	3.65	Yes	Yes	0	5	8
198	A:A:K293	A:A:N292	4.2	Yes	Yes	1	9	9
199	A:A:N292	A:A:T364	10.24	Yes	No	0	9	9
200	A:A:K293	A:A:L296	14.1	Yes	No	0	9	6
201	A:A:E327	A:A:Q294	3.82	Yes	No	8	4	6
202	A:A:K338	A:A:Q294	12.2	Yes	No	8	5	6
203	A:A:L297	A:A:V301	2.98	No	Yes	0	8	7
204	A:A:A298	A:A:V334	5.09	No	Yes	0	4	4
205	A:A:K300	A:A:V301	4.55	Yes	Yes	0	9	7
206	A:A:K300	A:A:S306	6.12	Yes	No	9	9	7
207	A:A:K300	A:A:K307	2.87	Yes	Yes	9	9	6
208	A:A:I308	A:A:K300	7.27	Yes	Yes	9	7	9
209	A:A:E309	A:A:K300	4.05	No	Yes	0	4	9
210	A:A:V301	A:A:V334	4.81	Yes	Yes	0	7	4
211	A:A:A337	A:A:V301	3.39	No	Yes	0	8	7
212	A:A:D331	A:A:L302	5.43	No	No	0	4	2
213	A:A:L302	A:A:V334	2.98	No	Yes	0	2	4
214	A:A:K307	A:A:S306	10.71	Yes	No	9	6	7
215	A:A:K307	A:A:Y311	4.78	Yes	No	9	6	6
216	A:A:F312	A:A:K307	2.48	Yes	Yes	9	8	6
217	A:A:F315	A:A:I308	8.79	Yes	Yes	9	6	7
218	A:A:A337	A:A:I308	3.25	No	Yes	9	8	7
219	A:A:F340	A:A:I308	2.51	Yes	Yes	9	7	7
220	A:A:D310	A:A:Y311	5.75	No	No	0	3	6
221	A:A:F312	A:A:F340	5.36	Yes	Yes	9	8	7
222	A:A:E314	A:A:R317	10.47	No	No	0	6	2
223	A:A:F315	A:A:R336	21.38	Yes	No	0	6	5
224	A:A:A337	A:A:F315	4.16	No	Yes	9	8	6
225	A:A:F315	A:A:F340	12.86	Yes	Yes	9	6	7
226	A:A:P321	A:A:Y318	6.95	No	No	0	5	6
227	A:A:F340	A:A:Y318	9.28	Yes	No	0	7	6
228	A:A:D343	A:A:Y318	6.9	No	No	0	3	6
229	A:A:P321	A:A:T320	3.5	No	No	0	5	1
230	A:A:R336	A:A:T320	3.88	No	No	0	5	1
231	A:A:D323	A:A:P321	3.22	No	No	0	4	5
232	A:A:A324	A:A:Y339	5.34	No	Yes	0	3	3
233	A:A:P326	A:A:T325	3.5	No	No	0	1	2
234	A:A:E327	A:A:T325	2.82	Yes	No	0	4	2
235	A:A:T325	A:A:Y339	6.24	No	Yes	0	2	3
236	A:A:P326	A:A:P328	3.9	No	No	0	1	1
237	A:A:E327	A:A:E330	6.34	Yes	Yes	8	4	3
238	A:A:E327	A:A:K338	4.05	Yes	Yes	8	4	5
239	A:A:E330	A:A:V334	11.41	Yes	Yes	0	3	4
240	A:A:E330	A:A:T335	9.88	Yes	No	0	3	4
241	A:A:E330	A:A:K338	4.05	Yes	Yes	8	3	5
242	A:A:D331	A:A:P332	3.22	No	No	0	4	1
243	A:A:T335	A:A:Y339	2.5	No	Yes	0	4	3
244	A:A:K338	A:A:Y339	3.58	Yes	Yes	8	5	3
245	A:A:F363	A:A:K338	14.89	Yes	Yes	8	5	5
246	A:A:R342	A:A:Y339	11.32	Yes	Yes	8	4	3
247	A:A:F363	A:A:Y339	9.28	Yes	Yes	8	5	3
248	A:A:F340	A:A:I341	3.77	Yes	No	0	7	8
249	A:A:E344	A:A:F340	13.99	No	Yes	0	5	7
250	A:A:L346	A:A:R342	4.86	No	Yes	8	4	4
251	A:A:P361	A:A:R342	4.32	No	Yes	8	5	4
252	A:A:F363	A:A:R342	6.41	Yes	Yes	8	5	4
253	A:A:D343	A:A:R347	4.76	No	No	0	3	4
254	A:A:L346	A:A:S349	3	No	Yes	8	4	7
255	A:A:L346	A:A:P361	3.28	No	No	8	4	5
256	A:A:C359	A:A:S349	6.89	Yes	Yes	8	5	7
257	A:A:R356	A:A:S352	3.95	Yes	No	0	2	5
258	A:A:D354	A:A:R356	13.1	No	Yes	0	3	2
259	A:A:G355	A:A:R385	6	No	Yes	0	2	5
260	A:A:H357	A:A:R356	11.28	No	Yes	0	7	2
261	A:A:Y358	A:A:Y360	12.91	No	Yes	1	4	8
262	A:A:Y358	R:R:V212	3.79	No	No	0	4	3
263	A:A:Y358	R:R:S213	7.63	No	Yes	1	4	3
264	A:A:H362	A:A:Y360	4.36	Yes	Yes	1	9	8
265	A:A:D378	A:A:Y360	21.84	No	Yes	1	7	8
266	A:A:D381	A:A:Y360	11.49	No	Yes	1	8	8
267	A:A:I382	A:A:Y360	6.04	Yes	Yes	1	6	8
268	A:A:Y360	R:R:S213	2.54	Yes	Yes	1	8	3
269	A:A:H362	A:A:R374	20.31	Yes	Yes	1	9	4
270	A:A:D378	A:A:H362	8.82	No	Yes	1	7	9
271	A:A:C365	A:A:E370	7.6	No	Yes	1	8	4
272	A:A:C365	A:A:R374	4.18	No	Yes	1	8	4
273	A:A:D368	A:A:T369	2.89	No	No	0	9	9
274	A:A:D368	A:A:E370	2.6	No	Yes	0	9	4
275	A:A:E370	A:A:N371	3.94	Yes	No	1	4	9
276	A:A:E370	A:A:R374	13.96	Yes	Yes	1	4	4
277	A:A:N371	A:A:R374	2.41	No	Yes	1	9	4
278	A:A:N377	A:A:R373	4.82	No	No	0	4	5
279	A:A:F376	A:A:N377	4.83	Yes	No	0	8	4
280	A:A:F376	R:R:L123	3.65	Yes	Yes	1	8	6
281	A:A:R380	R:R:P122	4.32	No	No	0	7	7
282	A:A:D381	R:R:V212	5.84	No	No	0	8	3
283	A:A:D381	R:R:S213	2.94	No	Yes	1	8	3
284	A:A:I382	A:A:M386	2.92	Yes	No	0	6	3
285	A:A:I383	A:A:M386	2.92	Yes	No	0	8	3
286	A:A:H387	A:A:I383	6.63	Yes	Yes	1	8	8
287	A:A:I383	R:R:P122	3.39	Yes	No	1	8	7
288	A:A:I383	R:R:L123	4.28	Yes	Yes	1	8	6
289	A:A:Q384	R:R:V119	2.87	No	No	0	6	8
290	A:A:Q384	R:R:A207	4.55	No	No	0	6	3
291	A:A:Q384	R:R:S211	4.33	No	Yes	0	6	5
292	A:A:R385	A:A:R389	5.33	Yes	No	0	5	4
293	A:A:L394	A:A:R385	2.43	No	Yes	1	8	5
294	A:A:R385	R:R:S213	9.22	Yes	Yes	1	5	3
295	A:A:R385	R:R:T214	6.47	Yes	No	1	5	3
296	A:A:R385	R:R:E218	11.63	Yes	Yes	1	5	5
297	A:A:H387	A:A:Q390	4.95	Yes	No	0	8	4
298	A:A:H387	R:R:A118	5.85	Yes	No	0	8	8
299	A:A:H387	R:R:P122	4.58	Yes	No	1	8	7
300	A:A:H387	R:R:R129	5.64	Yes	Yes	1	8	7
301	A:A:L388	A:A:L393	2.77	Yes	No	0	8	8
302	A:A:L388	R:R:V119	4.47	Yes	No	0	8	8
303	A:A:L388	R:R:V208	4.47	Yes	Yes	1	8	8
304	A:A:L388	R:R:I222	2.85	Yes	No	1	8	7
305	A:A:Q390	A:A:Y391	10.15	No	Yes	0	4	4
306	A:A:Q390	R:R:N50	2.64	No	No	0	4	7
307	A:A:Y391	R:R:L52	7.03	Yes	Yes	1	4	8
308	A:A:Y391	R:R:D114	10.34	Yes	Yes	1	4	8
309	A:A:Y391	R:R:A118	9.34	Yes	No	0	4	8
310	A:A:Y391	R:R:R129	5.14	Yes	Yes	1	4	7
311	A:A:E392	R:R:Q45	5.1	Yes	No	0	6	5
312	A:A:E392	R:R:L56	2.65	Yes	No	0	6	8
313	A:A:E392	R:R:N290	7.89	Yes	No	0	6	8
314	A:A:E392	R:R:A293	4.53	Yes	No	0	6	8
315	A:A:L393	R:R:R115	4.86	No	Yes	0	8	9
316	A:A:L393	R:R:I204	8.56	No	No	0	8	6
317	A:A:L394	R:R:E218	7.95	No	Yes	1	8	5
318	A:A:L394	R:R:I222	4.28	No	No	1	8	7
319	B:B:E3	B:B:Q6	3.82	No	No	0	5	1
320	B:B:E3	B:B:L7	3.98	No	No	0	5	8
321	B:B:L4	G:G:I9	2.85	No	No	0	4	2
322	B:B:L7	G:G:A12	3.15	No	No	0	8	5
323	B:B:E10	B:B:Q13	5.1	Yes	No	12	8	1
324	B:B:E10	B:B:L14	9.28	Yes	Yes	12	8	8
325	B:B:E10	G:G:V16	8.56	Yes	No	12	8	7
326	B:B:E10	G:G:K20	13.5	Yes	No	12	8	6
327	B:B:L14	B:B:Q13	5.32	Yes	No	12	8	1
328	B:B:L14	B:B:Q17	2.66	Yes	No	0	8	4
329	B:B:L14	G:G:L19	4.15	Yes	Yes	0	8	9
330	B:B:L14	G:G:K20	7.05	Yes	No	12	8	6
331	B:B:K15	G:G:L19	9.87	No	Yes	0	6	9
332	B:B:Q17	G:G:A23	3.03	No	No	0	4	8
333	B:B:I18	B:B:R22	6.26	Yes	No	5	7	6
334	B:B:I18	G:G:E22	2.73	Yes	Yes	0	7	9
335	B:B:I18	G:G:A23	3.25	Yes	No	0	7	8
336	B:B:I18	G:G:R27	2.51	Yes	Yes	5	7	8
337	B:B:Q259	B:B:R22	4.67	Yes	No	0	6	6
338	B:B:R22	G:G:R27	5.33	No	Yes	5	6	8
339	B:B:C25	B:B:Q259	3.05	No	Yes	0	3	6
340	B:B:C25	G:G:R27	2.79	No	Yes	0	3	8
341	B:B:A26	B:B:Q259	3.03	No	Yes	0	3	6
342	B:B:D27	G:G:K29	5.53	No	No	0	8	4
343	B:B:D27	G:G:S31	10.31	No	No	0	8	9
344	B:B:S31	B:B:T29	4.8	No	No	0	1	3
345	B:B:Q32	B:B:T29	18.43	No	No	0	1	3
346	B:B:L30	B:B:T34	7.37	Yes	No	0	5	5
347	B:B:L261	B:B:L30	6.92	Yes	Yes	4	5	5
348	B:B:L30	B:B:M262	8.48	Yes	Yes	4	5	4
349	B:B:M262	B:B:S31	4.6	Yes	No	0	4	1
350	B:B:K301	B:B:T34	4.5	Yes	No	0	5	5
351	B:B:K301	B:B:N35	2.8	Yes	No	0	5	1
352	B:B:I37	B:B:R283	8.77	No	Yes	0	2	9
353	B:B:I37	B:B:K301	2.91	No	Yes	0	2	5
354	B:B:R283	B:B:V40	7.85	Yes	Yes	4	9	3
355	B:B:L284	B:B:V40	4.47	No	Yes	0	5	3
356	B:B:D298	B:B:V40	8.76	No	Yes	4	9	3
357	B:B:V40	G:G:L51	5.96	Yes	No	4	3	6
358	B:B:Q44	B:B:R42	12.85	No	No	0	4	2
359	B:B:I43	B:B:M45	2.92	No	No	0	3	4
360	B:B:I43	G:G:L51	2.85	No	No	0	3	6
361	B:B:L308	B:B:M45	4.24	No	No	0	7	4
362	B:B:M45	G:G:L50	2.83	No	Yes	0	4	9
363	B:B:T47	B:B:T50	4.71	No	No	7	3	3
364	B:B:K337	B:B:T47	10.51	Yes	No	7	6	3
365	B:B:T47	B:B:W339	8.49	No	Yes	7	3	9
366	B:B:N340	B:B:R48	3.62	Yes	No	0	9	7
367	B:B:R49	B:B:T87	6.47	No	No	0	7	5
368	B:B:I338	B:B:R49	2.51	No	No	3	5	7
369	B:B:R49	G:G:F61	5.34	No	Yes	3	7	8
370	B:B:R52	B:B:T50	9.06	No	No	0	7	3
371	B:B:K337	B:B:T50	6.01	Yes	No	7	6	3
372	B:B:L51	B:B:W82	20.5	Yes	Yes	0	9	9
373	B:B:L51	B:B:T87	2.95	Yes	No	0	9	5
374	B:B:L336	B:B:L51	11.07	No	Yes	0	7	9
375	B:B:I338	B:B:L51	4.28	No	Yes	0	5	9
376	B:B:H54	B:B:I58	11.93	Yes	No	3	9	9
377	B:B:H54	B:B:S72	11.16	Yes	Yes	3	9	9
378	B:B:H54	B:B:S74	13.95	Yes	No	0	9	9
379	B:B:H54	B:B:I80	13.26	Yes	Yes	3	9	8
380	B:B:H54	B:B:W82	8.46	Yes	Yes	3	9	9
381	B:B:D76	B:B:L55	13.57	Yes	No	13	9	6
382	B:B:A56	B:B:D76	4.63	No	Yes	13	7	9
383	B:B:K57	B:B:Y59	4.78	Yes	Yes	2	9	8
384	B:B:K57	B:B:Q75	9.49	Yes	No	2	9	9
385	B:B:K57	B:B:W332	13.92	Yes	Yes	2	9	9
386	B:B:I58	B:B:S72	6.19	No	Yes	3	9	9
387	B:B:G330	B:B:I58	5.29	No	No	0	5	9
388	B:B:Q75	B:B:Y59	9.02	No	Yes	2	9	8
389	B:B:M101	B:B:Y59	8.38	Yes	Yes	2	9	8
390	B:B:W332	B:B:Y59	4.82	Yes	Yes	2	9	8
391	B:B:M61	B:B:W63	3.49	Yes	Yes	3	6	7
392	B:B:M61	B:B:S72	3.07	Yes	Yes	3	6	9
393	B:B:C317	B:B:M61	4.86	No	Yes	0	7	6
394	B:B:A328	B:B:M61	3.22	No	Yes	3	5	6
395	B:B:H62	B:B:R150	16.93	No	Yes	0	6	6
396	B:B:L70	B:B:W63	12.53	No	Yes	3	5	7
397	B:B:S84	B:B:W63	4.94	No	Yes	3	5	7
398	B:B:T321	B:B:W63	9.7	Yes	Yes	3	7	7
399	B:B:A326	B:B:W63	2.59	No	Yes	3	7	7
400	B:B:A328	B:B:W63	5.19	No	Yes	3	5	7
401	B:B:G64	B:B:Y105	7.24	No	Yes	0	5	6
402	B:B:D66	B:B:R68	2.38	No	No	0	8	5
403	B:B:D66	B:B:L69	6.79	No	Yes	0	8	5
404	B:B:S67	B:B:T321	4.8	No	Yes	3	5	7
405	B:B:D322	B:B:S67	4.42	No	No	0	1	5
406	B:B:D323	B:B:S67	8.83	No	No	3	7	5
407	B:B:D83	B:B:R68	11.91	No	No	0	8	5
408	B:B:R68	B:B:Y85	26.75	No	Yes	0	5	4
409	B:B:I81	B:B:L69	2.85	Yes	Yes	10	7	5
410	B:B:L69	B:B:V90	4.47	Yes	No	10	5	5
411	B:B:L69	B:B:Y105	5.86	Yes	Yes	10	5	6
412	B:B:A328	B:B:L70	3.15	No	No	3	5	5
413	B:B:L336	B:B:L70	5.54	No	No	0	7	5
414	B:B:L79	B:B:V71	2.98	Yes	Yes	10	7	8
415	B:B:C103	B:B:V71	3.42	No	Yes	0	8	8
416	B:B:V71	B:B:Y105	5.05	Yes	Yes	10	8	6
417	B:B:V112	B:B:V71	4.81	No	Yes	10	8	8
418	B:B:S72	B:B:W82	3.71	Yes	Yes	3	9	9
419	B:B:A73	B:B:V100	5.09	No	No	0	9	9
420	B:B:A73	B:B:C103	3.61	No	No	0	9	8
421	B:B:D76	B:B:S74	8.83	Yes	No	0	9	9
422	B:B:Q75	B:B:W99	8.76	No	Yes	2	9	9
423	B:B:I80	B:B:K78	4.36	Yes	No	0	8	8
424	B:B:I93	B:B:L79	2.85	Yes	Yes	0	7	7
425	B:B:L79	B:B:L95	9.69	Yes	Yes	10	7	8
426	B:B:C114	B:B:L79	4.76	Yes	Yes	10	8	7
427	B:B:I80	B:B:W82	17.62	Yes	Yes	3	8	9
428	B:B:I80	B:B:K89	4.36	Yes	Yes	3	8	9
429	B:B:I81	B:B:V90	4.61	Yes	No	10	7	5
430	B:B:H91	B:B:I81	9.28	No	Yes	10	5	7
431	B:B:I81	B:B:L126	4.28	Yes	Yes	10	7	5
432	B:B:K89	B:B:W82	9.28	Yes	Yes	3	9	9
433	B:B:D83	B:B:T86	8.67	No	No	3	8	6
434	B:B:S84	B:B:Y85	2.54	No	Yes	3	5	4
435	B:B:S84	G:G:F61	5.28	No	Yes	3	5	8
436	B:B:Y85	G:G:P60	13.91	Yes	Yes	3	4	9
437	B:B:Y85	G:G:F61	5.16	Yes	Yes	3	4	8
438	B:B:N88	B:B:T86	7.31	No	No	3	7	6
439	B:B:H91	B:B:V90	5.54	No	No	10	5	5
440	B:B:H91	B:B:V133	5.54	No	No	0	5	4
441	B:B:I93	B:B:P94	3.39	Yes	No	0	7	5
442	B:B:I93	B:B:Y124	6.04	Yes	Yes	0	7	6
443	B:B:I93	B:B:V133	4.61	Yes	No	0	7	4
444	B:B:L95	B:B:V100	4.47	Yes	No	10	8	9
445	B:B:C114	B:B:L95	4.76	Yes	Yes	10	8	8
446	B:B:L95	B:B:Y124	5.86	Yes	Yes	10	8	6
447	B:B:E138	B:B:R96	10.47	No	No	0	6	6
448	B:B:D118	B:B:S97	8.83	No	No	0	9	8
449	B:B:S98	B:B:W99	7.41	No	Yes	0	8	9
450	B:B:L117	B:B:W99	6.83	Yes	Yes	2	9	9
451	B:B:C114	B:B:V100	3.42	Yes	No	10	8	9
452	B:B:L117	B:B:M101	2.83	Yes	Yes	2	9	9
453	B:B:M101	B:B:Y145	4.79	Yes	Yes	2	9	8
454	B:B:C148	B:B:T102	3.38	No	No	0	6	8
455	B:B:C149	B:B:T102	8.45	No	No	0	8	8
456	B:B:G109	B:B:Y105	2.9	No	Yes	0	5	6
457	B:B:V112	B:B:Y105	5.05	No	Yes	10	8	6
458	B:B:L126	B:B:Y105	3.52	Yes	Yes	10	5	6
459	B:B:A106	B:B:F151	5.55	No	Yes	0	6	9
460	B:B:F151	B:B:P107	4.33	Yes	No	0	9	6
461	B:B:G109	B:B:N110	5.09	No	No	0	5	4
462	B:B:K127	B:B:N110	13.99	No	No	0	4	4
463	B:B:I123	B:B:Y111	4.84	Yes	Yes	2	6	4
464	B:B:N125	B:B:Y111	13.96	No	Yes	0	4	4
465	B:B:S136	B:B:Y111	2.54	No	Yes	2	4	4
466	B:B:D154	B:B:Y111	9.2	No	Yes	0	6	4
467	B:B:L126	B:B:V112	5.96	Yes	No	10	5	8
468	B:B:A113	B:B:I123	3.25	No	Yes	2	9	6
469	B:B:A113	B:B:F151	4.16	No	Yes	2	9	9
470	B:B:C114	B:B:Y124	4.03	Yes	Yes	10	8	6
471	B:B:G115	B:B:L146	3.42	No	Yes	0	9	7
472	B:B:D118	B:B:I120	13.99	No	No	0	9	6
473	B:B:G144	B:B:N119	5.09	No	No	0	8	9
474	B:B:E138	B:B:I120	9.56	No	No	0	6	6
475	B:B:C121	B:B:L139	4.76	Yes	No	0	8	9
476	B:B:C121	B:B:L146	3.17	Yes	Yes	2	8	7
477	B:B:C121	B:B:C149	3.64	Yes	No	0	8	8
478	B:B:C121	B:B:T159	3.38	Yes	Yes	2	8	9
479	B:B:S122	B:B:Y124	5.09	No	Yes	0	8	6
480	B:B:I123	B:B:S136	3.1	Yes	No	2	6	4
481	B:B:I123	B:B:L139	2.85	Yes	No	0	6	9
482	B:B:F151	B:B:I123	2.51	Yes	Yes	2	9	6
483	B:B:I123	B:B:I171	4.42	Yes	Yes	2	6	6
484	B:B:V135	B:B:Y124	7.57	No	Yes	0	4	6
485	B:B:N125	B:B:T128	2.92	No	No	0	4	3
486	B:B:K127	B:B:L126	5.64	No	Yes	0	4	5
487	B:B:L126	B:B:V133	2.98	Yes	No	0	5	4
488	B:B:E130	B:B:T128	2.82	Yes	No	0	3	3
489	B:B:E130	B:B:G131	4.91	Yes	No	0	3	4
490	B:B:E130	B:B:N132	11.83	Yes	No	0	3	3
491	B:B:I171	B:B:R137	2.51	Yes	No	0	6	5
492	B:B:G174	B:B:R137	4.5	No	No	0	4	5
493	B:B:L139	B:B:W169	15.94	No	Yes	0	9	8
494	B:B:H142	B:B:L146	5.14	Yes	Yes	2	9	7
495	B:B:H142	B:B:T159	6.85	Yes	Yes	2	9	9
496	B:B:H142	B:B:S161	13.95	Yes	No	2	9	9
497	B:B:D163	B:B:H142	7.56	Yes	Yes	2	9	9
498	B:B:H142	B:B:T165	2.74	Yes	No	2	9	7
499	B:B:A167	B:B:H142	4.39	No	Yes	2	4	9
500	B:B:H142	B:B:Q176	2.47	Yes	Yes	2	9	4
501	B:B:D163	B:B:T143	7.23	Yes	No	0	9	5
502	B:B:D163	B:B:G144	5.03	Yes	No	0	9	8
503	B:B:G162	B:B:Y145	7.24	No	Yes	2	9	8
504	B:B:D186	B:B:Y145	12.64	Yes	Yes	2	9	8
505	B:B:M188	B:B:Y145	3.59	Yes	Yes	2	8	8
506	B:B:L146	B:B:T159	5.9	Yes	Yes	2	7	9
507	B:B:S147	B:B:S160	4.89	No	No	0	9	6
508	B:B:C148	B:B:R150	5.57	No	Yes	6	6	6
509	B:B:C148	B:B:L190	4.76	No	Yes	6	6	5
510	B:B:L190	B:B:R150	3.64	Yes	Yes	6	5	6
511	B:B:L192	B:B:R150	2.43	No	Yes	0	5	6
512	B:B:F151	B:B:I157	7.54	Yes	No	2	9	7
513	B:B:F151	B:B:I171	3.77	Yes	Yes	2	9	6
514	B:B:D153	B:B:L152	5.43	No	Yes	6	5	3
515	B:B:L152	B:B:Q156	7.99	Yes	No	6	3	5
516	B:B:L152	B:B:T196	4.42	Yes	No	0	3	1
517	B:B:D153	B:B:Q156	2.61	No	No	6	5	5
518	B:B:D170	B:B:N155	9.42	No	No	0	9	3
519	B:B:I171	B:B:N155	2.83	Yes	No	0	6	3
520	B:B:E172	B:B:N155	9.2	No	No	0	6	3
521	B:B:L168	B:B:Q156	5.32	No	No	0	6	5
522	B:B:I157	B:B:T159	3.04	No	Yes	2	7	9
523	B:B:I157	B:B:W169	3.52	No	Yes	2	7	8
524	B:B:L190	B:B:V158	5.96	Yes	Yes	6	5	5
525	B:B:F199	B:B:V158	7.87	Yes	Yes	6	9	5
526	B:B:T159	B:B:W169	9.7	Yes	Yes	2	9	8
527	B:B:S160	B:B:V187	6.46	No	Yes	0	6	9
528	B:B:L190	B:B:S160	4.5	Yes	No	0	5	6
529	B:B:G162	B:B:S161	3.71	No	No	2	9	9
530	B:B:D163	B:B:S161	10.31	Yes	No	2	9	9
531	B:B:D186	B:B:G162	5.03	Yes	No	2	9	9
532	B:B:D163	B:B:T165	11.56	Yes	No	2	9	7
533	B:B:T165	B:B:T181	4.71	No	No	0	7	2
534	B:B:C166	B:B:F180	4.19	Yes	Yes	6	8	7
535	B:B:C166	B:B:V187	5.12	Yes	Yes	6	8	9
536	B:B:C166	B:B:F199	4.19	Yes	Yes	6	8	9
537	B:B:C166	B:B:S201	5.16	Yes	Yes	6	8	9
538	B:B:A167	B:B:W169	5.19	No	Yes	2	4	8
539	B:B:A167	B:B:Q176	4.55	No	Yes	2	4	4
540	B:B:Q176	B:B:W169	9.86	Yes	Yes	2	4	8
541	B:B:D170	B:B:T173	8.67	No	No	0	9	5
542	B:B:Q175	B:B:T173	2.83	No	No	0	4	5
543	B:B:Q176	B:B:T179	8.5	Yes	No	0	4	4
544	B:B:T177	B:B:T178	3.14	No	No	0	4	4
545	B:B:F180	B:B:T178	6.49	Yes	No	0	7	4
546	B:B:F180	B:B:F199	12.86	Yes	Yes	6	7	9
547	B:B:F180	B:B:W211	15.03	Yes	Yes	6	7	8
548	B:B:F180	B:B:G216	3.01	Yes	No	0	7	4
549	B:B:H183	B:B:V187	4.15	Yes	Yes	6	9	9
550	B:B:A203	B:B:H183	7.32	No	Yes	6	8	9
551	B:B:D205	B:B:H183	6.3	Yes	Yes	6	9	9
552	B:B:H183	B:B:S207	2.79	Yes	No	6	9	5
553	B:B:H183	B:B:K209	19.65	Yes	Yes	6	9	6
554	B:B:H183	B:B:W211	7.41	Yes	Yes	6	9	8
555	B:B:D205	B:B:T184	4.34	Yes	No	0	9	3
556	B:B:C204	B:B:D186	3.11	Yes	Yes	0	7	9
557	B:B:S201	B:B:V187	3.23	Yes	Yes	6	9	9
558	B:B:A203	B:B:V187	3.39	No	Yes	6	8	9
559	B:B:C204	B:B:M188	3.24	Yes	Yes	0	7	8
560	B:B:M188	B:B:N230	4.21	Yes	No	2	8	9
561	B:B:I232	B:B:S189	3.1	Yes	No	0	8	7
562	B:B:F199	B:B:L190	6.09	Yes	Yes	6	9	5
563	B:B:I232	B:B:S191	3.1	Yes	No	0	8	8
564	B:B:F234	B:B:S191	7.93	Yes	No	0	5	8
565	B:B:F199	B:B:L192	2.44	Yes	No	0	9	5
566	B:B:A193	B:B:D195	4.63	No	No	0	4	5
567	B:B:A193	B:B:F234	2.77	No	Yes	0	4	5
568	B:B:D195	B:B:R197	3.57	No	No	0	5	5
569	B:B:D212	B:B:R197	4.76	Yes	No	5	9	5
570	B:B:E215	B:B:R197	5.82	Yes	No	5	3	5
571	B:B:L198	B:B:L210	5.54	No	Yes	5	3	5
572	B:B:D212	B:B:L198	4.07	Yes	No	5	9	3
573	B:B:L198	B:B:R219	2.43	No	No	5	3	5
574	B:B:F199	B:B:S201	3.96	Yes	Yes	6	9	9
575	B:B:F199	B:B:W211	9.02	Yes	Yes	6	9	8
576	B:B:F199	B:B:V213	2.62	Yes	No	0	9	4
577	B:B:L210	B:B:V200	4.47	Yes	Yes	5	5	6
578	B:B:I232	B:B:V200	6.14	Yes	Yes	5	8	6
579	B:B:F234	B:B:V200	7.87	Yes	Yes	0	5	6
580	B:B:F241	B:B:V200	17.04	Yes	Yes	5	6	6
581	B:B:S201	B:B:W211	4.94	Yes	Yes	6	9	8
582	B:B:G202	B:B:I229	3.53	No	No	0	6	7
583	B:B:A203	B:B:D205	3.09	No	Yes	6	8	9
584	B:B:C204	B:B:D228	12.45	Yes	Yes	0	7	9
585	B:B:D205	B:B:S207	10.31	Yes	No	6	9	5
586	B:B:K209	B:B:S207	3.06	Yes	No	6	6	5
587	B:B:A208	B:B:F222	2.77	No	Yes	5	6	8
588	B:B:A208	B:B:F241	2.77	No	Yes	5	6	6
589	B:B:K209	B:B:W211	6.96	Yes	Yes	6	6	8
590	B:B:C218	B:B:K209	6.47	No	Yes	6	5	6
591	B:B:K209	B:B:T221	9.01	Yes	No	0	6	7
592	B:B:L210	B:B:Q220	2.66	Yes	Yes	5	5	7
593	B:B:L210	B:B:L255	8.3	Yes	Yes	5	5	6
594	B:B:C218	B:B:W211	5.22	No	Yes	6	5	8
595	B:B:D212	B:B:E215	15.59	Yes	Yes	5	9	3
596	B:B:D212	B:B:M217	2.77	Yes	No	5	9	3
597	B:B:D212	B:B:R219	14.29	Yes	No	5	9	5
598	B:B:E215	B:B:R214	3.49	Yes	No	0	3	9
599	B:B:E215	B:B:M217	4.06	Yes	No	5	3	3
600	B:B:M217	B:B:R219	6.2	No	No	5	3	5
601	B:B:F222	B:B:Q220	4.68	Yes	Yes	5	8	7
602	B:B:L255	B:B:Q220	2.66	Yes	Yes	5	6	7
603	B:B:D258	B:B:Q220	16.97	Yes	Yes	5	7	7
604	B:B:Q220	G:G:I25	6.86	Yes	No	5	7	2
605	B:B:T221	G:G:E22	5.64	No	Yes	0	7	9
606	B:B:F222	B:B:F241	6.43	Yes	Yes	5	8	6
607	B:B:F222	B:B:F253	7.5	Yes	Yes	5	8	6
608	B:B:F222	B:B:L255	3.65	Yes	Yes	5	8	6
609	B:B:D258	B:B:F222	5.97	Yes	Yes	5	7	8
610	B:B:E260	B:B:G224	4.91	No	No	0	6	6
611	B:B:H225	B:B:I229	7.95	Yes	No	5	9	7
612	B:B:H225	B:B:T243	8.21	Yes	Yes	5	9	8
613	B:B:H225	B:B:S245	8.37	Yes	No	5	9	9
614	B:B:D247	B:B:H225	5.04	Yes	Yes	5	9	9
615	B:B:H225	B:B:R251	22.57	Yes	Yes	5	9	8
616	B:B:F253	B:B:H225	4.53	Yes	Yes	5	6	9
617	B:B:D247	B:B:E226	10.39	Yes	No	0	9	3
618	B:B:D228	B:B:S227	5.89	Yes	No	0	9	6
619	B:B:S227	B:B:S245	3.26	No	No	0	6	9
620	B:B:D246	B:B:S227	2.94	No	No	0	9	6
621	B:B:I229	B:B:T243	9.12	No	Yes	5	7	8
622	B:B:D246	B:B:N230	5.39	No	No	2	9	9
623	B:B:A231	B:B:V276	3.39	No	No	0	5	6
624	B:B:F241	B:B:I232	5.02	Yes	Yes	5	6	8
625	B:B:I232	B:B:T243	3.04	Yes	Yes	5	8	8
626	B:B:C233	B:B:F278	4.19	No	Yes	0	3	7
627	B:B:F234	B:B:G238	3.01	Yes	No	0	5	7
628	B:B:F234	B:B:L255	2.44	Yes	Yes	0	5	6
629	B:B:F235	B:B:P236	17.34	Yes	Yes	4	6	7
630	B:B:F235	B:B:N237	6.04	Yes	No	4	6	5
631	B:B:F235	B:B:F278	9.65	Yes	Yes	4	6	7
632	B:B:F235	B:B:G282	4.52	Yes	No	4	6	9
633	B:B:F235	G:G:L37	10.96	Yes	No	0	6	7
634	B:B:F235	G:G:Y40	4.13	Yes	Yes	4	6	6
635	B:B:F235	G:G:C41	4.19	Yes	No	4	6	7
636	B:B:F278	B:B:P236	2.89	Yes	Yes	4	7	7
637	B:B:G282	B:B:P236	4.06	No	Yes	4	9	7
638	B:B:P236	G:G:Y40	8.34	Yes	Yes	4	7	6
639	B:B:N237	B:B:N239	9.54	No	No	0	5	2
640	B:B:N237	G:G:Y40	12.79	No	Yes	4	5	6
641	B:B:N239	B:B:R256	6.03	No	Yes	0	2	9
642	B:B:F241	B:B:T243	2.59	Yes	Yes	5	6	8
643	B:B:F241	B:B:F253	15	Yes	Yes	5	6	6
644	B:B:F241	B:B:L255	2.44	Yes	Yes	5	6	6
645	B:B:A242	B:B:F278	4.16	No	Yes	4	4	7
646	B:B:A242	B:B:L285	3.15	No	Yes	4	4	6
647	B:B:F253	B:B:T243	9.08	Yes	Yes	5	6	8
648	B:B:G244	B:B:I273	5.29	No	No	0	5	6
649	B:B:D247	B:B:S245	8.83	Yes	No	5	9	9
650	B:B:D247	B:B:T249	8.67	Yes	No	5	9	6
651	B:B:D247	B:B:R251	2.38	Yes	Yes	5	9	8
652	B:B:R251	B:B:T249	3.88	Yes	No	5	8	6
653	B:B:S265	B:B:T249	4.8	No	No	0	2	6
654	B:B:C250	B:B:Y264	5.38	No	Yes	4	8	5
655	B:B:C250	B:B:L285	4.76	No	Yes	4	8	6
656	B:B:E260	B:B:R251	12.79	No	Yes	0	6	8
657	B:B:R251	B:B:T263	11.64	Yes	No	0	8	1
658	B:B:L252	B:B:L261	5.54	No	Yes	0	7	5
659	B:B:L252	B:B:Y264	4.69	No	Yes	0	7	5
660	B:B:E260	B:B:F253	4.66	No	Yes	0	6	6
661	B:B:D254	B:B:R256	2.38	No	Yes	0	9	9
662	B:B:A257	B:B:D254	3.09	No	No	0	7	9
663	B:B:D254	G:G:A33	6.18	No	No	0	9	7
664	B:B:R256	G:G:I28	6.26	Yes	No	0	9	4
665	B:B:R256	G:G:D36	10.72	Yes	No	0	9	5
666	B:B:D258	G:G:I25	2.8	Yes	No	5	7	2
667	B:B:D258	G:G:R27	15.48	Yes	Yes	5	7	8
668	B:B:Q259	G:G:V30	7.16	Yes	No	0	6	8
669	B:B:L261	G:G:V30	2.98	Yes	No	0	5	8
670	B:B:M262	B:B:Y264	8.38	Yes	Yes	4	4	5
671	B:B:A302	B:B:M262	3.22	No	Yes	4	2	4
672	B:B:S265	B:B:T263	3.2	No	No	0	2	1
673	B:B:L285	B:B:Y264	7.03	Yes	Yes	4	6	5
674	B:B:W297	B:B:Y264	15.43	Yes	Yes	4	8	5
675	B:B:A302	B:B:Y264	4	No	Yes	4	2	5
676	B:B:H266	B:B:N268	12.75	Yes	No	4	4	4
677	B:B:H266	B:B:I269	2.65	Yes	Yes	4	4	4
678	B:B:H266	B:B:R304	12.41	Yes	Yes	4	4	5
679	B:B:I269	B:B:N268	5.66	Yes	No	4	4	4
680	B:B:N268	B:B:R304	6.03	No	Yes	4	4	5
681	B:B:I269	B:B:Y289	6.04	Yes	Yes	4	4	7
682	B:B:I269	B:B:W297	3.52	Yes	Yes	4	4	8
683	B:B:I269	B:B:R304	2.51	Yes	Yes	4	4	5
684	B:B:C271	B:B:Y289	2.69	No	Yes	0	5	7
685	B:B:C271	B:B:D290	4.67	No	Yes	0	5	6
686	B:B:D290	B:B:G272	3.35	Yes	No	0	6	4
687	B:B:A287	B:B:I273	3.25	No	No	4	6	6
688	B:B:I273	B:B:Y289	13.3	No	Yes	4	6	7
689	B:B:S275	B:B:T274	3.2	No	No	0	8	8
690	B:B:D290	B:B:T274	5.78	Yes	No	2	6	8
691	B:B:R314	B:B:T274	10.35	Yes	No	2	8	8
692	B:B:G288	B:B:S275	3.71	No	No	0	7	8
693	B:B:L318	B:B:S275	7.51	No	No	0	6	8
694	B:B:L285	B:B:V276	2.98	Yes	No	0	6	6
695	B:B:L318	B:B:S277	4.5	No	No	0	6	5
696	B:B:G319	B:B:S277	3.71	No	No	0	5	5
697	B:B:S277	B:B:V320	3.23	No	No	0	5	7
698	B:B:F278	B:B:G282	3.01	Yes	No	4	7	9
699	B:B:F278	B:B:L285	8.53	Yes	Yes	4	7	6
700	B:B:A299	B:B:F278	2.77	No	Yes	0	5	7
701	B:B:L284	B:B:S279	6.01	No	No	0	5	9
702	B:B:S279	G:G:D48	5.89	No	Yes	7	9	9
703	B:B:S279	G:G:L50	6.01	No	Yes	7	9	9
704	B:B:K280	G:G:E47	5.4	No	No	0	1	3
705	B:B:K280	G:G:D48	2.77	No	Yes	0	1	9
706	B:B:S281	G:G:D48	10.31	No	Yes	0	9	9
707	B:B:D298	B:B:R283	15.48	No	Yes	4	9	9
708	B:B:L300	B:B:R283	12.15	No	Yes	4	6	9
709	B:B:R283	G:G:C41	4.18	Yes	No	4	9	7
710	B:B:R283	G:G:L51	2.43	Yes	No	4	9	6
711	B:B:L284	B:B:V296	5.96	No	No	0	5	5
712	B:B:L286	B:B:V296	4.47	No	No	0	7	5
713	B:B:L286	B:B:V327	2.98	No	Yes	7	7	6
714	B:B:L286	G:G:L50	2.77	No	Yes	7	7	9
715	B:B:A287	B:B:Y289	5.34	No	Yes	4	6	7
716	B:B:C294	B:B:G288	3.92	No	No	7	5	7
717	B:B:G288	B:B:V315	3.68	No	Yes	7	7	7
718	B:B:N295	B:B:Y289	10.47	Yes	Yes	4	6	7
719	B:B:W297	B:B:Y289	10.61	Yes	Yes	4	8	7
720	B:B:D290	B:B:R314	13.1	Yes	Yes	2	6	8
721	B:B:D291	B:B:N293	8.08	No	No	0	8	5
722	B:B:F292	B:B:N313	3.62	No	No	0	4	7
723	B:B:N293	B:B:N295	2.72	No	Yes	4	5	6
724	B:B:N293	B:B:V307	4.43	No	No	4	5	3
725	B:B:C294	B:B:L308	6.35	No	No	0	5	7
726	B:B:C294	B:B:V315	5.12	No	Yes	7	5	7
727	B:B:N295	B:B:W297	7.91	Yes	Yes	4	6	8
728	B:B:N295	B:B:R304	8.44	Yes	Yes	4	6	5
729	B:B:N295	B:B:V307	2.96	Yes	No	4	6	3
730	B:B:G306	B:B:V296	3.68	No	No	0	4	5
731	B:B:D298	B:B:K301	4.15	No	Yes	0	9	5
732	B:B:L300	G:G:M38	2.83	No	No	0	6	4
733	B:B:L300	G:G:C41	4.76	No	No	4	6	7
734	B:B:R304	B:B:V307	2.62	Yes	No	4	5	3
735	B:B:L308	B:B:W339	13.67	No	Yes	0	7	9
736	B:B:H311	B:B:V315	4.15	Yes	Yes	7	9	7
737	B:B:H311	B:B:T329	6.85	Yes	Yes	7	9	8
738	B:B:H311	B:B:S331	13.95	Yes	No	7	9	9
739	B:B:D333	B:B:H311	11.35	Yes	Yes	7	9	9
740	B:B:H311	B:B:K337	9.17	Yes	Yes	7	9	6
741	B:B:N313	B:B:W332	6.78	No	Yes	0	7	9
742	B:B:R314	B:B:W332	14.99	Yes	Yes	2	8	9
743	B:B:T329	B:B:V315	3.17	Yes	Yes	7	8	7
744	B:B:S331	B:B:V315	4.85	No	Yes	7	9	7
745	B:B:S316	B:B:W332	4.94	No	Yes	0	9	9
746	B:B:L318	B:B:T329	5.9	No	Yes	0	6	8
747	B:B:V320	B:B:V327	3.21	No	Yes	7	7	6
748	B:B:V320	G:G:L50	2.98	No	Yes	7	7	9
749	B:B:D323	B:B:T321	7.23	No	Yes	3	7	7
750	B:B:G324	B:B:T321	3.64	No	Yes	0	9	7
751	B:B:A326	B:B:T321	3.36	No	Yes	3	7	7
752	B:B:D323	B:B:M325	8.32	No	No	0	7	5
753	B:B:M325	G:G:P49	10.06	No	No	0	5	7
754	B:B:M325	G:G:P60	5.03	No	Yes	0	5	9
755	B:B:A326	G:G:F61	5.55	No	Yes	3	7	8
756	B:B:V327	B:B:W339	3.68	Yes	Yes	7	6	9
757	B:B:V327	G:G:L50	4.47	Yes	Yes	7	6	9
758	B:B:T329	B:B:W339	9.7	Yes	Yes	7	8	9
759	B:B:D333	B:B:S331	5.89	Yes	No	7	9	9
760	B:B:D333	B:B:F335	10.75	Yes	No	0	9	4
761	B:B:F335	B:B:S334	6.61	No	No	0	4	4
762	B:B:K337	B:B:W339	9.28	Yes	Yes	7	6	9
763	B:B:I338	G:G:F61	6.28	No	Yes	3	5	8
764	B:B:N340	G:G:V54	2.96	Yes	Yes	3	9	6
765	B:B:N340	G:G:N59	10.9	Yes	Yes	3	9	9
766	B:B:N340	G:G:F61	2.42	Yes	Yes	3	9	8
767	G:G:I9	G:G:T6	6.08	No	No	0	2	3
768	G:G:K14	G:G:Q11	6.78	No	No	0	4	3
769	G:G:E17	G:G:K14	2.7	No	No	0	6	4
770	G:G:L15	G:G:L19	4.15	No	Yes	0	2	9
771	G:G:K20	G:G:V16	3.04	No	No	12	6	7
772	G:G:E22	G:G:Q18	7.65	Yes	No	0	9	9
773	G:G:E22	G:G:L19	5.3	Yes	Yes	0	9	9
774	G:G:I28	G:G:K32	4.36	No	No	0	4	5
775	G:G:A33	G:G:I28	3.25	No	No	0	7	4
776	G:G:H44	G:G:Y40	19.6	No	Yes	0	6	6
777	G:G:A43	G:G:H44	2.93	No	No	0	4	6
778	G:G:E47	G:G:H44	3.69	No	No	0	3	6
779	G:G:D48	G:G:P49	3.22	Yes	No	0	9	7
780	G:G:D48	G:G:L50	4.07	Yes	Yes	7	9	9
781	G:G:P49	G:G:V54	3.53	No	Yes	0	7	6
782	G:G:P53	G:G:T52	3.5	No	No	0	8	4
783	G:G:P55	G:G:V54	3.53	No	Yes	3	5	6
784	G:G:E58	G:G:V54	4.28	No	Yes	3	5	6
785	G:G:N59	G:G:V54	4.43	Yes	Yes	3	9	6
786	G:G:E58	G:G:P55	12.58	No	No	3	5	5
787	G:G:N59	G:G:P60	6.52	Yes	Yes	3	9	9
788	G:G:F61	G:G:N59	4.83	Yes	Yes	3	8	9
789	G:G:F61	G:G:P60	7.22	Yes	Yes	3	8	9
790	R:R:E7	R:R:R162	3.49	No	No	0	4	4
791	R:R:G8	R:R:P173	4.06	No	No	0	5	4
792	R:R:C258	R:R:C9	5.46	No	No	0	8	8
793	R:R:C9	R:R:E261	3.04	No	No	0	8	4
794	R:R:H10	R:R:Y163	16.33	No	No	0	3	3
795	R:R:H165	R:R:V11	5.54	Yes	No	1	1	3
796	R:R:F172	R:R:V11	3.93	Yes	No	1	5	3
797	R:R:F265	R:R:V11	13.11	Yes	No	1	4	3
798	R:R:D16	R:R:S13	10.31	Yes	No	1	5	5
799	R:R:F265	R:R:S13	6.61	Yes	No	1	4	5
800	R:R:R14	R:R:V15	10.46	No	No	0	2	4
801	R:R:F19	R:R:V15	6.55	Yes	No	0	5	4
802	R:R:D16	R:R:F265	8.36	Yes	Yes	1	5	4
803	R:R:D16	R:R:S266	8.83	Yes	No	0	5	2
804	R:R:D16	R:R:H269	18.91	Yes	Yes	1	5	5
805	R:R:H17	R:R:L18	6.43	No	No	0	5	4
806	R:R:H17	R:R:H80	10.75	No	No	0	5	4
807	R:R:F19	R:R:P20	14.45	Yes	No	14	5	5
808	R:R:F19	R:R:L23	2.44	Yes	Yes	14	5	5
809	R:R:F19	R:R:S270	2.64	Yes	No	0	5	5
810	R:R:A273	R:R:F19	2.77	No	Yes	14	5	5
811	R:R:P20	R:R:P21	5.84	No	No	0	5	7
812	R:R:A273	R:R:P20	3.74	No	No	14	5	5
813	R:R:L78	R:R:P21	8.21	No	No	0	7	7
814	R:R:A273	R:R:L23	3.15	No	Yes	14	5	5
815	R:R:L23	R:R:S276	4.5	Yes	No	0	5	7
816	R:R:L23	R:R:L277	4.15	Yes	No	0	5	5
817	R:R:L70	R:R:Y24	7.03	Yes	Yes	1	8	9
818	R:R:V74	R:R:Y24	6.31	No	Yes	0	7	9
819	R:R:F77	R:R:Y24	9.28	Yes	Yes	1	5	9
820	R:R:F97	R:R:Y24	4.13	Yes	Yes	1	7	9
821	R:R:L272	R:R:Y24	3.52	Yes	Yes	1	5	9
822	R:R:S276	R:R:Y24	5.09	No	Yes	0	7	9
823	R:R:I25	R:R:V74	3.07	No	No	0	4	7
824	R:R:F26	R:R:V27	2.62	No	No	0	4	7
825	R:R:F26	R:R:V30	9.18	No	No	0	4	6
826	R:R:F26	R:R:L277	2.44	No	No	0	4	5
827	R:R:I28	R:R:I67	4.42	Yes	No	0	7	6
828	R:R:I28	R:R:L70	7.14	Yes	Yes	0	7	8
829	R:R:I28	R:R:P71	3.39	Yes	No	0	7	8
830	R:R:V280	R:R:V30	6.41	No	No	0	8	6
831	R:R:G31	R:R:T34	3.64	No	Yes	0	8	7
832	R:R:G31	R:R:V280	3.68	No	No	0	8	8
833	R:R:L32	R:R:P33	4.93	No	No	0	6	5
834	R:R:I67	R:R:L32	2.85	No	No	0	6	6
835	R:R:N35	R:R:T34	2.92	No	Yes	1	9	7
836	R:R:P283	R:R:T34	6.99	No	Yes	1	9	7
837	R:R:I284	R:R:T34	4.56	No	Yes	0	7	7
838	R:R:D63	R:R:N35	10.77	Yes	No	1	9	9
839	R:R:N35	R:R:P283	9.77	No	No	1	9	9
840	R:R:L37	R:R:V297	2.98	No	No	0	7	7
841	R:R:A38	R:R:C287	3.61	No	No	0	9	8
842	R:R:L39	R:R:M57	2.83	No	No	0	7	5
843	R:R:L39	R:R:S60	7.51	No	No	0	7	8
844	R:R:W40	R:R:Y43	7.72	No	No	0	4	4
845	R:R:A300	R:R:W40	2.59	No	No	0	3	4
846	R:R:A42	R:R:M57	3.22	No	No	0	7	5
847	R:R:Q47	R:R:Y43	7.89	No	No	0	6	4
848	R:R:M57	R:R:Y43	4.79	No	No	0	5	4
849	R:R:Q47	R:R:R44	9.35	No	No	0	6	4
850	R:R:Q48	R:R:R44	17.52	No	No	0	7	4
851	R:R:Q45	R:R:Q48	5.12	No	No	0	5	7
852	R:R:N50	R:R:Q45	14.52	No	No	0	7	5
853	R:R:V131	R:R:V46	3.21	No	No	0	3	6
854	R:R:L52	R:R:N50	2.75	Yes	No	0	8	7
855	R:R:E51	R:R:Y55	12.35	Yes	Yes	1	7	7
856	R:R:D114	R:R:E51	15.59	Yes	Yes	1	8	7
857	R:R:E51	R:R:R129	3.49	Yes	Yes	1	7	7
858	R:R:A134	R:R:E51	4.53	No	Yes	1	5	7
859	R:R:I111	R:R:L52	4.28	Yes	Yes	1	9	8
860	R:R:D114	R:R:L52	6.79	Yes	Yes	1	8	8
861	R:R:L52	R:R:R115	6.07	Yes	Yes	1	8	9
862	R:R:A134	R:R:V54	5.09	No	No	0	5	5
863	R:R:V135	R:R:V54	3.21	No	No	0	4	5
864	R:R:S138	R:R:V54	3.23	Yes	No	0	7	5
865	R:R:C110	R:R:Y55	4.03	No	Yes	0	7	7
866	R:R:I111	R:R:Y55	3.63	Yes	Yes	1	9	7
867	R:R:D114	R:R:Y55	6.9	Yes	Yes	1	8	7
868	R:R:A134	R:R:Y55	4	No	Yes	1	5	7
869	R:R:S138	R:R:Y55	2.54	Yes	Yes	1	7	7
870	R:R:I111	R:R:L56	2.85	Yes	No	0	9	8
871	R:R:C287	R:R:L56	3.17	No	No	0	8	8
872	R:R:F107	R:R:N58	14.5	Yes	No	1	8	7
873	R:R:N58	R:R:S138	8.94	No	Yes	1	7	7
874	R:R:N58	R:R:W142	6.78	No	Yes	1	7	9
875	R:R:D63	R:R:L59	4.07	Yes	Yes	1	9	9
876	R:R:L59	R:R:S104	4.5	Yes	No	1	9	9
877	R:R:F107	R:R:L59	2.44	Yes	Yes	1	8	9
878	R:R:L108	R:R:L59	5.54	Yes	Yes	1	8	9
879	R:R:D282	R:R:L59	4.07	Yes	Yes	1	9	9
880	R:R:I61	R:R:W142	4.7	No	Yes	0	5	9
881	R:R:A62	R:R:W142	2.59	No	Yes	0	8	9
882	R:R:C279	R:R:D63	6.22	No	Yes	0	9	9
883	R:R:D282	R:R:D63	3.99	Yes	Yes	1	9	9
884	R:R:L65	R:R:N100	4.12	No	No	0	7	8
885	R:R:L70	R:R:Y66	8.21	Yes	Yes	1	8	7
886	R:R:F97	R:R:Y66	10.32	Yes	Yes	1	7	7
887	R:R:N100	R:R:Y66	4.65	No	Yes	0	8	7
888	R:R:I101	R:R:Y66	3.63	Yes	Yes	1	8	7
889	R:R:S276	R:R:Y66	3.82	No	Yes	0	7	7
890	R:R:C279	R:R:I67	3.27	No	No	0	9	6
891	R:R:F93	R:R:T69	9.08	No	Yes	0	6	7
892	R:R:I96	R:R:T69	9.12	No	Yes	0	5	7
893	R:R:F97	R:R:T69	3.89	Yes	Yes	0	7	7
894	R:R:F97	R:R:L70	2.44	Yes	Yes	1	7	8
895	R:R:L72	R:R:W83	3.42	No	Yes	0	7	9
896	R:R:F93	R:R:L72	12.18	No	No	0	6	7
897	R:R:W73	R:R:Y76	7.72	Yes	Yes	1	7	6
898	R:R:F77	R:R:W73	4.01	Yes	Yes	1	5	7
899	R:R:W73	R:R:W83	12.18	Yes	Yes	1	7	9
900	R:R:G94	R:R:W73	4.22	No	Yes	0	8	7
901	R:R:F97	R:R:W73	23.05	Yes	Yes	1	7	7
902	R:R:W73	R:R:Y98	2.89	Yes	Yes	1	7	5
903	R:R:C168	R:R:W73	5.22	Yes	Yes	1	9	7
904	R:R:D75	R:R:H79	13.87	No	No	1	4	4
905	R:R:D75	R:R:I84	2.8	No	No	1	4	3
906	R:R:D75	R:R:H85	2.52	No	Yes	1	4	7
907	R:R:F77	R:R:Y76	9.28	Yes	Yes	1	5	6
908	R:R:D81	R:R:Y76	10.34	Yes	Yes	1	4	6
909	R:R:W83	R:R:Y76	8.68	Yes	Yes	1	9	6
910	R:R:F167	R:R:Y76	7.22	Yes	Yes	1	1	6
911	R:R:F77	R:R:H269	18.1	Yes	Yes	1	5	5
912	R:R:F77	R:R:L272	2.44	Yes	Yes	1	5	5
913	R:R:H79	R:R:I84	5.3	No	No	1	4	3
914	R:R:D81	R:R:H165	3.78	Yes	Yes	1	4	1
915	R:R:D81	R:R:F167	7.17	Yes	Yes	1	4	1
916	R:R:D81	R:R:F172	2.39	Yes	Yes	1	4	5
917	R:R:D81	R:R:F265	11.94	Yes	Yes	1	4	4
918	R:R:D81	R:R:H269	11.35	Yes	Yes	1	4	5
919	R:R:N82	R:R:T166	5.85	No	No	0	5	3
920	R:R:H85	R:R:W83	3.17	Yes	Yes	1	7	9
921	R:R:C90	R:R:W83	7.84	No	Yes	1	9	9
922	R:R:C168	R:R:W83	14.37	Yes	Yes	1	9	9
923	R:R:H85	R:R:I84	2.65	Yes	No	1	7	3
924	R:R:G86	R:R:P87	4.06	No	No	0	8	3
925	R:R:L158	R:R:P87	9.85	No	No	0	5	3
926	R:R:C168	R:R:C90	7.28	Yes	No	1	9	9
927	R:R:K91	R:R:L153	4.23	No	No	0	6	4
928	R:R:E157	R:R:K91	6.75	No	No	0	5	6
929	R:R:F93	R:R:L92	4.87	No	No	0	6	5
930	R:R:F169	R:R:G94	3.01	Yes	No	0	4	8
931	R:R:F95	R:R:I96	2.51	Yes	No	0	6	5
932	R:R:F95	R:R:T99	2.59	Yes	No	0	6	5
933	R:R:F95	R:R:L146	2.44	Yes	No	0	6	3
934	R:R:F95	R:R:S150	5.28	Yes	No	0	6	4
935	R:R:F95	R:R:L153	6.09	Yes	No	0	6	4
936	R:R:I96	R:R:N100	2.83	No	No	0	5	8
937	R:R:F97	R:R:Y98	10.32	Yes	Yes	1	7	5
938	R:R:F97	R:R:L272	4.87	Yes	Yes	1	7	5
939	R:R:F169	R:R:Y98	3.09	Yes	Yes	1	4	5
940	R:R:E170	R:R:Y98	11.22	No	Yes	0	4	5
941	R:R:Y240	R:R:Y98	4.96	Yes	Yes	1	6	5
942	R:R:N149	R:R:T99	8.77	Yes	No	0	7	5
943	R:R:I101	R:R:Y102	13.3	Yes	Yes	1	8	7
944	R:R:F237	R:R:I101	2.51	Yes	Yes	1	8	8
945	R:R:H241	R:R:I101	2.65	Yes	Yes	1	8	8
946	R:R:I101	R:R:T275	3.04	Yes	No	1	8	8
947	R:R:N149	R:R:Y102	3.49	Yes	Yes	1	7	7
948	R:R:R185	R:R:Y102	14.4	No	Yes	0	5	7
949	R:R:G189	R:R:Y102	2.9	No	Yes	0	6	7
950	R:R:H241	R:R:Y102	7.62	Yes	Yes	1	8	7
951	R:R:F107	R:R:I103	3.77	Yes	No	1	8	7
952	R:R:I103	R:R:W142	10.57	No	Yes	1	7	9
953	R:R:E145	R:R:I103	5.47	No	No	0	7	7
954	R:R:D282	R:R:S104	2.94	Yes	No	1	9	9
955	R:R:F190	R:R:I105	2.51	Yes	No	1	8	8
956	R:R:I105	R:R:P193	5.08	No	No	0	8	9
957	R:R:F237	R:R:I105	5.02	Yes	No	1	8	8
958	R:R:F107	R:R:S138	2.64	Yes	Yes	1	8	7
959	R:R:F107	R:R:V141	3.93	Yes	No	0	8	7
960	R:R:F107	R:R:W142	12.03	Yes	Yes	1	8	9
961	R:R:L108	R:R:M197	11.31	Yes	No	0	8	7
962	R:R:D282	R:R:L108	8.14	Yes	Yes	1	9	8
963	R:R:L108	R:R:Y286	9.38	Yes	Yes	1	8	9
964	R:R:C109	R:R:P193	3.77	No	No	0	8	9
965	R:R:C109	R:R:L196	4.76	No	No	0	8	4
966	R:R:I111	R:R:R115	5.01	Yes	Yes	1	9	9
967	R:R:I111	R:R:Y286	4.84	Yes	Yes	1	9	9
968	R:R:S112	R:R:V113	3.23	Yes	No	0	9	6
969	R:R:M197	R:R:S112	6.13	No	Yes	0	7	9
970	R:R:S112	R:R:S200	6.52	Yes	No	0	9	8
971	R:R:S112	R:R:Y201	3.82	Yes	Yes	0	9	8
972	R:R:D114	R:R:R129	2.38	Yes	Yes	1	8	7
973	R:R:R115	R:R:Y201	8.23	Yes	Yes	1	9	8
974	R:R:R115	R:R:Y286	3.09	Yes	Yes	1	9	9
975	R:R:A120	R:R:Y116	8.01	No	Yes	11	7	8
976	R:R:H121	R:R:Y116	6.53	Yes	Yes	11	6	8
977	R:R:S200	R:R:Y116	2.54	No	Yes	0	8	8
978	R:R:G203	R:R:Y116	2.9	No	Yes	0	3	8
979	R:R:F125	R:R:L117	2.44	Yes	No	0	6	6
980	R:R:A120	R:R:H121	5.85	No	Yes	11	7	6
981	R:R:H121	R:R:R124	4.51	Yes	No	11	6	4
982	R:R:F125	R:R:H121	4.53	Yes	Yes	11	6	6
983	R:R:F125	R:R:R124	8.55	Yes	No	11	6	4
984	R:R:F125	R:R:R127	5.34	Yes	No	11	6	4
985	R:R:F125	R:R:L128	4.87	Yes	No	11	6	3
986	R:R:L128	R:R:R127	4.86	No	No	11	3	4
987	R:R:R127	R:R:R130	3.2	No	No	0	4	6
988	R:R:K132	R:R:R130	2.48	No	No	0	4	6
989	R:R:R130	R:R:T133	2.59	No	No	0	6	3
990	R:R:E145	R:R:N149	2.63	No	Yes	0	7	7
991	R:R:G147	R:R:S150	3.71	No	No	0	4	4
992	R:R:A148	R:R:Y184	2.67	No	Yes	0	5	3
993	R:R:M181	R:R:N149	4.21	Yes	Yes	1	4	7
994	R:R:N149	R:R:Y184	6.98	Yes	Yes	1	7	3
995	R:R:E157	R:R:P152	3.14	No	Yes	1	5	3
996	R:R:F169	R:R:P152	4.33	Yes	Yes	1	4	3
997	R:R:P152	R:R:W177	6.76	Yes	Yes	0	3	1
998	R:R:M181	R:R:P152	6.71	Yes	Yes	1	4	3
999	R:R:H155	R:R:W177	25.39	No	Yes	0	4	1
1000	R:R:E157	R:R:F169	15.16	No	Yes	1	5	4
1001	R:R:F159	R:R:K171	19.85	No	No	0	2	3
1002	R:R:R160	R:R:T166	6.47	No	No	0	1	3
1003	R:R:D161	R:R:Y163	8.05	No	No	0	2	3
1004	R:R:D161	R:R:H165	12.61	No	Yes	0	2	1
1005	R:R:R162	R:R:Y163	5.14	No	No	0	4	3
1006	R:R:H165	R:R:N164	3.83	Yes	No	0	1	4
1007	R:R:F167	R:R:H165	9.05	Yes	Yes	1	1	1
1008	R:R:F167	R:R:F172	16.08	Yes	Yes	1	1	5
1009	R:R:C168	R:R:F169	2.79	Yes	Yes	1	9	4
1010	R:R:E170	R:R:Y268	12.35	No	Yes	0	4	5
1011	R:R:K171	R:R:P173	15.06	No	No	0	3	4
1012	R:R:E175	R:R:K171	8.1	No	No	0	2	3
1013	R:R:F172	R:R:F265	8.57	Yes	Yes	1	5	4
1014	R:R:M174	R:R:V178	4.56	No	No	0	1	2
1015	R:R:M174	R:R:S248	3.07	No	No	0	1	5
1016	R:R:M174	R:R:Y251	13.17	No	Yes	0	1	3
1017	R:R:E175	R:R:W177	4.36	No	Yes	0	2	1
1018	R:R:G176	R:R:Y251	4.35	No	Yes	0	4	3
1019	R:R:V178	R:R:W177	8.58	No	Yes	0	2	1
1020	R:R:N182	R:R:V178	4.43	Yes	No	0	5	2
1021	R:R:A179	R:R:Y251	2.67	No	Yes	0	1	3
1022	R:R:L252	R:R:W180	6.83	No	No	0	6	3
1023	R:R:M181	R:R:Y184	4.79	Yes	Yes	1	4	3
1024	R:R:M181	R:R:R185	8.69	Yes	No	0	4	5
1025	R:R:N182	R:R:R185	9.64	Yes	No	0	5	5
1026	R:R:L244	R:R:N182	5.49	Yes	Yes	0	5	5
1027	R:R:N182	R:R:S248	2.98	Yes	No	0	5	5
1028	R:R:F187	R:R:L183	2.44	No	No	0	5	4
1029	R:R:V188	R:R:Y184	7.57	No	Yes	0	4	3
1030	R:R:H241	R:R:V186	9.69	Yes	No	0	8	4
1031	R:R:L244	R:R:V186	4.47	Yes	No	0	5	4
1032	R:R:F187	R:R:L245	2.44	No	No	0	5	6
1033	R:R:F190	R:R:L191	7.31	Yes	No	0	8	4
1034	R:R:F190	R:R:F237	6.43	Yes	Yes	1	8	8
1035	R:R:F190	R:R:H241	20.36	Yes	Yes	1	8	8
1036	R:R:F192	R:R:P193	4.33	No	No	0	5	9
1037	R:R:F192	R:R:L196	2.44	No	No	0	5	4
1038	R:R:L198	R:R:W194	3.42	No	Yes	1	5	6
1039	R:R:I230	R:R:W194	4.7	No	Yes	1	7	6
1040	R:R:V233	R:R:W194	6.13	No	Yes	1	9	6
1041	R:R:L234	R:R:W194	13.67	No	Yes	0	6	6
1042	R:R:I230	R:R:L198	4.28	No	No	1	7	5
1043	R:R:I204	R:R:Y201	3.63	No	Yes	0	6	8
1044	R:R:A226	R:R:Y201	2.67	No	Yes	0	7	8
1045	R:R:L229	R:R:Y201	12.89	No	Yes	1	8	8
1046	R:R:I230	R:R:Y201	6.04	No	Yes	1	7	8
1047	R:R:Y201	R:R:Y286	3.97	Yes	Yes	1	8	9
1048	R:R:K223	R:R:L205	4.23	No	No	0	6	5
1049	R:R:A226	R:R:L205	4.73	No	No	0	7	5
1050	R:R:R206	R:R:R209	3.2	No	No	0	3	4
1051	R:R:S211	R:R:V208	3.23	Yes	Yes	1	5	8
1052	R:R:K219	R:R:V208	3.04	No	Yes	1	6	8
1053	R:R:I222	R:R:V208	10.75	No	Yes	1	7	8
1054	R:R:S211	R:R:T214	7.99	Yes	No	1	5	3
1055	R:R:K219	R:R:S211	4.59	No	Yes	1	6	5
1056	R:R:K219	R:R:T214	10.51	No	No	1	6	3
1057	R:R:E215	R:R:E218	12.69	No	Yes	0	3	5
1058	R:R:E218	R:R:Q217	5.1	Yes	No	0	5	4
1059	R:R:E291	R:R:K221	5.4	No	No	0	5	7
1060	R:R:K223	R:R:L227	4.23	No	No	0	6	5
1061	R:R:L285	R:R:S228	4.5	No	No	0	5	6
1062	R:R:L229	R:R:L285	5.54	No	No	0	8	5
1063	R:R:L229	R:R:Y286	11.72	No	Yes	1	8	9
1064	R:R:C236	R:R:I232	3.27	No	No	0	8	7
1065	R:R:A281	R:R:I232	3.25	No	No	0	5	7
1066	R:R:I232	R:R:L285	4.28	No	No	0	7	5
1067	R:R:F237	R:R:V233	3.93	Yes	No	1	8	9
1068	R:R:N278	R:R:V233	2.96	Yes	No	1	9	9
1069	R:R:F274	R:R:V235	2.62	No	No	0	7	5
1070	R:R:C236	R:R:F237	4.19	No	Yes	1	8	8
1071	R:R:C236	R:R:N278	3.15	No	Yes	1	8	9
1072	R:R:F237	R:R:T275	9.08	Yes	No	1	8	8
1073	R:R:F237	R:R:N278	10.87	Yes	Yes	1	8	9
1074	R:R:P239	R:R:S271	3.56	No	No	0	9	7
1075	R:R:H241	R:R:Y240	3.27	Yes	Yes	1	8	6
1076	R:R:L244	R:R:Y240	12.89	Yes	Yes	1	5	6
1077	R:R:Y240	R:R:Y268	11.91	Yes	Yes	1	6	5
1078	R:R:S271	R:R:Y240	3.82	No	Yes	0	7	6
1079	R:R:L272	R:R:Y240	14.07	Yes	Yes	1	5	6
1080	R:R:T275	R:R:Y240	7.49	No	Yes	1	8	6
1081	R:R:L243	R:R:S246	3	No	No	0	6	4
1082	R:R:L243	R:R:S271	4.5	No	No	0	6	7
1083	R:R:L244	R:R:Y268	8.21	Yes	Yes	1	5	5
1084	R:R:F260	R:R:S246	3.96	No	No	0	1	4
1085	R:R:E261	R:R:R247	13.96	No	No	0	4	4
1086	R:R:R247	R:R:V264	2.62	No	No	0	4	4
1087	R:R:R247	R:R:Y268	16.46	No	Yes	0	4	5
1088	R:R:I250	R:R:R254	2.51	No	No	0	1	2
1089	R:R:F260	R:R:I250	8.79	No	No	0	1	1
1090	R:R:P255	R:R:Y251	4.17	No	Yes	0	2	3
1091	R:R:G253	R:R:R254	3	No	No	0	3	2
1092	R:R:R254	R:R:W256	8	No	No	0	2	3
1093	R:R:P255	R:R:W256	8.11	No	No	0	2	3
1094	R:R:F260	R:R:V264	15.73	No	No	0	1	4
1095	R:R:F265	R:R:H269	14.71	Yes	Yes	1	4	5
1096	R:R:F274	R:R:L277	7.31	No	No	0	7	5
1097	R:R:D282	R:R:N278	13.46	Yes	Yes	1	9	9
1098	R:R:I284	R:R:L288	5.71	No	No	0	7	7
1099	R:R:N290	R:R:V289	2.96	No	No	0	8	6
1100	R:R:E291	R:R:R294	6.98	No	No	0	5	8
1101	R:R:G292	R:R:S295	3.71	No	No	0	6	4
1102	R:R:D296	R:R:V297	2.92	No	No	0	4	7
1103	R:R:L252	R:R:Y251	2.34	No	Yes	0	6	3
1104	B:B:E130	B:B:R134	2.33	Yes	No	0	3	3
1105	R:R:E262	R:R:R263	2.33	No	No	0	3	3
1106	R:R:L183	R:R:W180	2.28	No	No	0	4	3
1107	R:R:F154	R:R:H155	2.26	No	No	0	4	4
1108	B:B:G115	B:B:G116	2.11	No	No	0	9	9
1109	A:A:G329	A:A:P328	2.03	No	No	0	7	1
1110	B:B:G238	B:B:P194	2.03	No	No	0	7	4
1111	R:R:G88	R:R:P87	2.03	No	No	0	2	3
1112	B:B:C204	B:B:G185	1.96	Yes	No	0	7	5
1113	A:A:A226	A:A:G206	1.95	No	No	0	9	8
1114	B:B:A140	B:B:G141	1.95	No	No	0	5	5
1115	B:B:A309	B:B:G310	1.95	No	No	0	3	5
1116	R:R:A42	R:R:G53	1.95	No	No	0	7	7
1117	R:R:A151	R:R:P152	1.87	No	Yes	0	7	3
1118	R:R:A238	R:R:P239	1.87	No	No	0	5	9
1119	B:B:G77	B:B:S98	1.86	No	No	0	8	8
1120	A:A:G225	A:A:V224	1.84	No	Yes	0	9	9
1121	R:R:G53	R:R:V46	1.84	No	No	0	7	6
1122	B:B:G182	B:B:T181	1.82	No	No	0	6	2
1123	B:B:G224	B:B:T223	1.82	No	No	0	6	2
1124	B:B:A60	B:B:C103	1.81	No	No	0	7	8
1125	B:B:A104	B:B:C149	1.81	No	No	0	7	8
1126	R:R:A41	R:R:C287	1.81	No	No	0	7	8
1127	G:G:P55	G:G:S57	1.78	No	No	0	5	6
1128	R:R:G29	R:R:I28	1.76	No	Yes	0	5	7
1129	B:B:P107	B:B:T65	1.75	No	No	0	6	1
1130	B:B:G53	B:B:K89	1.74	No	Yes	0	9	9
1131	B:B:G310	B:B:K337	1.74	No	Yes	0	5	6
1132	R:R:G88	R:R:K91	1.74	No	No	0	2	6
1133	B:B:A28	G:G:S31	1.71	No	No	0	4	9
1134	R:R:C110	R:R:V137	1.71	No	No	0	7	5
1135	R:R:A267	R:R:S270	1.71	No	No	0	5	5
1136	A:A:A269	A:A:V248	1.7	No	No	0	9	7
1137	B:B:A11	G:G:V16	1.7	No	No	0	5	7
1138	B:B:A305	B:B:V40	1.7	No	Yes	0	4	3
1139	R:R:A106	R:R:V141	1.7	No	No	0	6	7
1140	R:R:C68	R:R:T69	1.69	No	Yes	0	5	7
1141	A:A:D354	A:A:G355	1.68	No	No	0	3	2
1142	R:R:D257	R:R:G259	1.68	No	No	0	5	2
1143	B:B:K301	B:B:P39	1.67	Yes	No	0	5	1
1144	B:B:G306	B:B:Q44	1.64	No	No	0	4	4
1145	B:B:G141	B:B:Q176	1.64	No	Yes	0	5	4
1146	R:R:E262	R:R:G259	1.64	No	No	0	3	2
1147	R:R:E291	R:R:G292	1.64	No	No	0	5	6
1148	B:B:A28	B:B:I33	1.62	No	No	0	4	3
1149	B:B:I33	G:G:A34	1.62	No	No	0	3	6
1150	B:B:A140	B:B:I120	1.62	No	No	0	5	6
1151	B:B:A248	B:B:I269	1.62	No	Yes	0	5	4
1152	B:B:D38	B:B:P39	1.61	No	No	0	1	1
1153	R:R:A220	R:R:K223	1.61	No	No	0	5	6
1154	A:A:T40	A:A:V36	1.59	No	No	0	7	2
1155	A:A:G353	A:A:H357	1.59	No	No	0	4	7
1156	R:R:T144	R:R:V141	1.59	No	No	0	5	7
1157	B:B:L4	G:G:A12	1.58	No	No	0	4	5
1158	B:B:L30	G:G:A34	1.58	Yes	No	4	5	6
1159	B:B:A240	B:B:L252	1.58	No	No	0	6	7
1160	B:B:A240	G:G:L37	1.58	No	No	0	6	7
1161	B:B:L261	G:G:A34	1.58	Yes	No	4	5	6
1162	G:G:A23	G:G:N24	1.56	No	No	0	8	1
1163	R:R:A41	R:R:D296	1.54	No	No	0	7	4
1164	R:R:A293	R:R:D296	1.54	No	No	0	8	4
1165	G:G:A10	G:G:Q11	1.52	No	No	0	2	3
1166	B:B:L4	G:G:S8	1.5	No	No	0	4	4
1167	R:R:G203	R:R:R202	1.5	No	No	0	3	3
1168	R:R:G203	R:R:R206	1.5	No	No	0	3	3
1169	R:R:G210	R:R:R209	1.5	No	No	0	4	4
1170	R:R:L225	R:R:S228	1.5	No	No	0	8	6
1171	B:B:L152	B:B:V158	1.49	Yes	Yes	6	3	5
1172	B:B:L152	B:B:V213	1.49	Yes	No	0	3	4
1173	B:B:L168	B:B:V158	1.49	No	Yes	0	6	5
1174	B:B:L168	B:B:V213	1.49	No	No	0	6	4
1175	B:B:A206	B:B:H225	1.46	No	Yes	0	4	9
1176	A:A:F312	A:A:P313	1.44	Yes	No	0	8	6
1177	A:A:I235	A:A:L46	1.43	No	No	0	9	8
1178	A:A:I276	A:A:L46	1.43	No	No	0	8	8
1179	R:R:D257	R:R:I250	1.4	No	No	0	5	1
1180	R:R:H85	R:R:S89	1.39	Yes	No	0	7	6
1181	B:B:D303	B:B:K301	1.38	No	Yes	0	2	5
1182	G:G:A10	G:G:R13	1.38	No	No	0	2	6
1183	R:R:L39	R:R:L64	1.38	No	No	0	7	8
1184	R:R:L198	R:R:L199	1.38	No	No	0	5	4
1185	A:A:K32	A:A:Q29	1.36	No	No	0	4	4
1186	A:A:K32	A:A:Q35	1.36	No	No	0	4	3
1187	A:A:D11	A:A:N14	1.35	No	No	0	2	3
1188	B:B:D312	B:B:D333	1.33	No	Yes	0	5	9
1189	A:A:R333	A:A:V301	1.31	No	Yes	0	5	7
1190	B:B:D5	B:B:Q9	1.31	No	No	0	1	3
1191	R:R:H79	R:R:N82	1.28	No	No	0	4	5
1192	B:B:D267	B:B:H266	1.26	No	Yes	0	3	4
1193	G:G:I9	G:G:R13	1.25	No	No	0	2	6
1194	B:B:K23	B:B:R19	1.24	No	No	0	2	4
1195	A:A:N14	A:A:R13	1.21	No	No	0	3	4
1196	A:A:F212	A:A:R61	1.07	Yes	No	0	9	8
1197	B:B:R46	B:B:R48	1.07	No	No	0	5	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	A:A:Q19	6.6375	4	3	4
2	A:A:Y37	9.2425	4	13	4
3	A:A:H41	4.142	5	1	6
4	A:A:R42	9.1975	4	0	9
5	A:A:I56	4.805	4	1	7
6	A:A:M60	4.2	4	1	9
7	A:A:I207	5.488	5	2	9
8	A:A:F212	5.3925	4	1	9
9	A:A:V214	5.5625	4	1	6
10	A:A:F219	5.44	6	1	8
11	A:A:M221	4.855	4	1	8
12	A:A:F222	10.2883	6	2	7
13	A:A:V224	4.59	4	0	9
14	A:A:Q227	5.855	4	0	9
15	A:A:R228	8.375	4	2	9
16	A:A:K233	7.48167	6	2	9
17	A:A:W234	6.36	4	0	9
18	A:A:C237	3.1675	4	2	8
19	A:A:F238	6.4325	8	2	9
20	A:A:T242	4.195	4	1	8
21	A:A:I245	3.5875	4	1	7
22	A:A:N264	8.06	5	9	9
23	A:A:L266	4.12	5	9	8
24	A:A:F273	5.09	7	8	9
25	A:A:W277	10.796	5	8	6
26	A:A:W281	12.768	5	2	5
27	A:A:L282	6.514	5	15	9
28	A:A:I288	5.624	5	1	9
29	A:A:F290	5.445	6	1	9
30	A:A:L291	4.19	4	0	8
31	A:A:N292	6.815	4	1	9
32	A:A:K293	6.615	4	1	9
33	A:A:K300	4.972	5	9	9
34	A:A:V301	3.408	5	0	7
35	A:A:K307	6.91	7	9	6
36	A:A:I308	5.455	4	9	7
37	A:A:F312	5.1	6	9	8
38	A:A:F315	11.7975	4	9	6
39	A:A:E327	4.2575	4	8	4
40	A:A:E330	7.92	4	8	3
41	A:A:V334	6.0725	4	0	4
42	A:A:K338	7.754	5	8	5
43	A:A:Y339	6.37667	6	8	3
44	A:A:F340	7.96167	6	9	7
45	A:A:R342	6.7275	4	8	4
46	A:A:F345	7.1925	4	0	8
47	A:A:S349	4.3675	4	8	7
48	A:A:R356	7.258	5	16	2
49	A:A:C359	5.2175	4	8	5
50	A:A:Y360	9.36286	7	1	8
51	A:A:H362	9.035	4	1	9
52	A:A:F363	8.5575	4	8	5
53	A:A:E370	7.025	4	1	4
54	A:A:R374	9.24	5	1	4
55	A:A:V375	4.46	4	1	9
56	A:A:F376	6.062	5	1	8
57	A:A:I382	4.9275	4	1	6
58	A:A:I383	4.26	6	1	8
59	A:A:R385	6.84667	6	1	5
60	A:A:H387	5.53	5	1	8
61	A:A:L388	3.64	4	1	8
62	A:A:Y391	8.4	5	1	4
63	A:A:E392	5.0425	4	0	6
64	B:B:E10	9.11	4	12	8
65	B:B:L14	5.692	5	12	8
66	B:B:I18	3.6875	4	5	7
67	B:B:L30	6.0875	4	4	5
68	B:B:V40	5.748	5	4	3
69	B:B:L51	9.7	4	0	9
70	B:B:H54	11.752	5	3	9
71	B:B:K57	9.248	5	2	9
72	B:B:Y59	6.206	5	2	8
73	B:B:M61	3.66	4	3	6
74	B:B:W63	6.40667	6	3	7
75	B:B:L69	4.9925	4	10	5
76	B:B:V71	4.065	4	10	8
77	B:B:S72	6.0325	4	3	9
78	B:B:D76	7.62	4	13	9
79	B:B:L79	5.07	4	10	7
80	B:B:I80	8.776	5	3	8
81	B:B:I81	5.255	4	10	7
82	B:B:W82	11.914	5	3	9
83	B:B:Y85	12.09	4	3	4
84	B:B:K89	6.36714	7	3	9
85	B:B:I93	4.2225	4	0	7
86	B:B:L95	6.195	4	10	8
87	B:B:W99	9.34143	7	2	9
88	B:B:M101	4.81	4	2	9
89	B:B:Y105	4.93667	6	10	6
90	B:B:Y111	7.635	4	2	4
91	B:B:C114	4.2425	4	10	8
92	B:B:L117	4.34	5	2	9
93	B:B:C121	3.7375	4	2	8
94	B:B:I123	3.495	6	2	6
95	B:B:Y124	5.718	5	10	6
96	B:B:L126	4.476	5	10	5
97	B:B:E130	5.4725	4	0	3
98	B:B:H142	6.15714	7	2	9
99	B:B:Y145	7.07	6	2	8
100	B:B:L146	4.4075	4	2	7
101	B:B:R150	7.1425	4	6	6
102	B:B:F151	4.64333	6	2	9
103	B:B:L152	4.164	5	6	3
104	B:B:V158	4.2025	4	6	5
105	B:B:T159	5.774	5	2	9
106	B:B:D163	8.338	5	2	9
107	B:B:C166	4.665	4	6	8
108	B:B:W169	8.842	5	2	8
109	B:B:I171	3.3825	4	2	6
110	B:B:Q176	5.404	5	2	4
111	B:B:F180	8.316	5	6	7
112	B:B:H183	7.93667	6	6	9
113	B:B:D186	7.5775	4	2	9
114	B:B:V187	4.47	5	6	9
115	B:B:M188	4.2	4	2	8
116	B:B:L190	4.99	5	6	5
117	B:B:F199	6.13125	8	6	9
118	B:B:V200	8.88	4	5	6
119	B:B:S201	4.3225	4	6	9
120	B:B:C204	5.19	4	0	7
121	B:B:D205	6.01	4	6	9
122	B:B:K209	9.03	5	6	6
123	B:B:L210	5.2425	4	5	5
124	B:B:W211	8.09667	6	6	8
125	B:B:D212	8.296	5	5	9
126	B:B:E215	7.24	4	5	3
127	B:B:Q220	6.766	5	5	7
128	B:B:F222	5.16667	6	5	8
129	B:B:H225	8.30429	7	5	9
130	B:B:D228	9.29	4	2	9
131	B:B:I232	4.08	5	5	8
132	B:B:F234	4.804	5	0	5
133	B:B:F235	8.11857	7	4	6
134	B:B:P236	8.1575	4	4	7
135	B:B:F241	7.32714	7	5	6
136	B:B:T243	6.408	5	5	8
137	B:B:D247	7.062	5	5	9
138	B:B:R251	10.652	5	5	8
139	B:B:F253	8.154	5	5	6
140	B:B:L255	3.898	5	5	6
141	B:B:R256	6.3475	4	0	9
142	B:B:D258	10.305	4	5	7
143	B:B:Q259	4.4775	4	0	6
144	B:B:L261	4.255	4	4	5
145	B:B:M262	6.17	4	4	4
146	B:B:Y264	7.485	6	4	5
147	B:B:H266	7.2675	4	4	4
148	B:B:I269	3.66667	6	4	4
149	B:B:F278	5.02857	7	4	7
150	B:B:R283	8.47667	6	4	9
151	B:B:L285	5.29	5	4	6
152	B:B:Y289	8.075	6	4	7
153	B:B:D290	6.89333	6	2	6
154	B:B:N295	6.5	5	4	6
155	B:B:W297	9.3675	4	4	8
156	B:B:K301	2.90167	6	0	5
157	B:B:R304	6.402	5	4	5
158	B:B:H311	9.094	5	7	9
159	B:B:R314	12.054	5	2	8
160	B:B:V315	4.194	5	7	7
161	B:B:T321	5.746	5	3	7
162	B:B:V327	3.585	4	7	6
163	B:B:T329	6.405	4	7	8
164	B:B:W332	8.77714	7	2	9
165	B:B:D333	7.33	4	7	9
166	B:B:K337	7.342	5	7	6
167	B:B:W339	8.964	5	7	9
168	B:B:N340	4.975	4	3	9
169	G:G:L19	5.8675	4	0	9
170	G:G:E22	5.33	4	0	9
171	G:G:R27	6.5275	4	5	8
172	G:G:Y40	11.215	4	4	6
173	G:G:D48	5.252	5	7	9
174	G:G:L50	3.855	6	7	9
175	G:G:V54	3.746	5	3	6
176	G:G:N59	6.67	4	3	9
177	G:G:P60	8.17	4	3	9
178	G:G:F61	5.26	8	3	8
179	R:R:D16	11.6025	4	1	5
180	R:R:F19	5.77	5	14	5
181	R:R:L23	3.56	4	14	5
182	R:R:Y24	5.89333	6	1	9
183	R:R:I28	4.1775	4	0	7
184	R:R:T34	4.5275	4	1	7
185	R:R:E51	8.99	4	1	7
186	R:R:L52	5.384	5	1	8
187	R:R:Y55	5.575	6	1	7
188	R:R:L59	4.124	5	1	9
189	R:R:D63	6.2625	4	1	9
190	R:R:Y66	6.126	5	1	7
191	R:R:T69	5.945	4	0	7
192	R:R:L70	6.205	4	1	8
193	R:R:W73	8.47	7	1	7
194	R:R:Y76	8.648	5	1	6
195	R:R:F77	8.622	5	1	5
196	R:R:D81	7.82833	6	1	4
197	R:R:W83	8.27667	6	1	9
198	R:R:H85	2.4325	4	1	7
199	R:R:F95	3.782	5	0	6
200	R:R:F97	8.43143	7	1	7
201	R:R:Y98	6.496	5	1	5
202	R:R:I101	5.026	5	1	8
203	R:R:Y102	8.342	5	1	7
204	R:R:F107	6.55167	6	1	8
205	R:R:L108	8.5925	4	1	8
206	R:R:I111	4.122	5	1	9
207	R:R:S112	4.925	4	0	9
208	R:R:D114	8.4	5	1	8
209	R:R:R115	5.452	5	1	9
210	R:R:Y116	4.995	4	11	8
211	R:R:H121	5.355	4	11	6
212	R:R:L123	4.385	4	1	6
213	R:R:F125	5.146	5	11	6
214	R:R:R129	4.1625	4	1	7
215	R:R:S138	4.3375	4	1	7
216	R:R:W142	7.334	5	1	9
217	R:R:N149	5.216	5	1	7
218	R:R:P152	4.562	5	1	3
219	R:R:H165	6.962	5	1	1
220	R:R:F167	9.88	4	1	1
221	R:R:C168	7.415	4	1	9
222	R:R:F169	5.676	5	1	4
223	R:R:F172	7.7425	4	1	5
224	R:R:W177	11.2725	4	0	1
225	R:R:M181	6.1	4	1	4
226	R:R:N182	5.635	4	0	5
227	R:R:Y184	5.5025	4	1	3
228	R:R:F190	9.1525	4	1	8
229	R:R:W194	6.98	4	1	6
230	R:R:Y201	5.89286	7	1	8
231	R:R:V208	5.3725	4	1	8
232	R:R:S211	5.035	4	1	5
233	R:R:S213	5.5825	4	1	3
234	R:R:E218	9.3425	4	1	5
235	R:R:F237	6.00429	7	1	8
236	R:R:Y240	8.34429	7	1	6
237	R:R:H241	8.718	5	1	8
238	R:R:L244	7.765	4	1	5
239	R:R:Y251	5.34	5	0	3
240	R:R:F265	10.55	6	1	4
241	R:R:Y268	12.2325	4	1	5
242	R:R:H269	15.7675	4	1	5
243	R:R:L272	6.225	4	1	5
244	R:R:N278	7.61	4	1	9
245	R:R:D282	6.52	5	1	9
246	R:R:Y286	6.6	5	1	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	B:B:H54	B:B:S74	54.9403	13.95	Yes	No	0	9	9
2	B:B:D76	B:B:S74	55.552	8.83	Yes	No	0	9	9
3	B:B:H54	B:B:W82	25.8098	8.46	Yes	Yes	3	9	9
4	A:A:Y37	B:B:D76	56.1185	3.45	Yes	Yes	13	4	9
5	A:A:R42	A:A:Y37	62.3991	23.66	Yes	Yes	0	9	4
6	A:A:F222	A:A:R42	38.162	5.34	Yes	Yes	0	7	9
7	A:A:F222	A:A:F238	28.1974	3.22	Yes	Yes	2	7	9
8	A:A:F238	A:A:L44	17.6585	21.92	Yes	No	0	9	9
9	A:A:I244	A:A:L44	17.528	4.28	No	No	0	8	9
10	A:A:I244	A:A:L282	17.5574	4.28	No	Yes	15	8	9
11	A:A:I276	A:A:L282	17.6903	5.71	No	Yes	0	8	9
12	A:A:F246	A:A:I276	17.7459	2.51	No	No	0	9	8
13	A:A:F246	A:A:F273	100	3.22	No	Yes	0	9	9
14	A:A:F273	A:A:W277	83.3501	4.01	Yes	Yes	8	9	6
15	A:A:H357	A:A:W277	86.7981	34.91	No	Yes	0	7	6
16	A:A:H357	A:A:R356	86.724	11.28	No	Yes	0	7	2
17	A:A:D354	A:A:R356	86.6712	13.1	No	Yes	0	3	2
18	A:A:D354	A:A:G355	86.6338	1.68	No	No	0	3	2
19	A:A:G355	A:A:R385	86.5963	6	No	Yes	0	2	5
20	A:A:R385	R:R:S213	11.7005	9.22	Yes	Yes	1	5	3
21	A:A:Y360	R:R:S213	11.2386	2.54	Yes	Yes	1	8	3
22	A:A:R42	A:A:V241	27.4108	2.62	Yes	No	0	9	9
23	A:A:F238	A:A:V241	27.6412	3.93	Yes	No	0	9	9
24	A:A:F238	A:A:V224	26.4956	2.62	Yes	Yes	0	9	9
25	A:A:V224	A:A:W234	21.8698	11.03	Yes	Yes	0	9	9
26	A:A:R231	A:A:W234	82.3292	8	No	Yes	0	9	9
27	A:A:L272	A:A:R231	82.3133	10.93	No	No	0	8	9
28	A:A:F246	A:A:L272	82.2824	7.31	No	No	0	9	8
29	A:A:Q227	B:B:L117	10.7889	5.32	Yes	Yes	0	9	9
30	A:A:Q227	B:B:Y145	11.9344	11.27	Yes	Yes	0	9	8
31	B:B:M101	B:B:Y145	24.6767	4.79	Yes	Yes	2	9	8
32	A:A:W234	B:B:Y145	68.6035	2.89	Yes	Yes	0	9	8
33	B:B:D186	B:B:Y145	11.3045	12.64	Yes	Yes	2	9	8
34	B:B:R68	B:B:Y85	27.8028	26.75	No	Yes	0	5	4
35	A:A:K233	A:A:Q236	11.8688	9.49	Yes	No	2	9	8
36	B:B:M188	B:B:Y145	53.8573	3.59	Yes	Yes	2	8	8
37	A:A:K233	B:B:M188	32.3049	5.76	Yes	Yes	2	9	8
38	A:A:K233	B:B:D228	11.1524	6.91	Yes	Yes	2	9	9
39	B:B:C204	B:B:D186	11.2668	3.11	Yes	Yes	0	7	9
40	B:B:C204	B:B:D228	21.793	12.45	Yes	Yes	0	7	9
41	B:B:C204	B:B:M188	10.8222	3.24	Yes	Yes	0	7	8
42	B:B:M188	B:B:N230	10.7325	4.21	Yes	No	2	8	9
43	A:A:K233	B:B:D246	11.1321	6.91	Yes	No	2	9	9
44	B:B:D246	B:B:N230	10.6653	5.39	No	No	2	9	9
45	B:B:W332	B:B:Y59	11.8528	4.82	Yes	Yes	2	9	8
46	A:A:L289	A:A:L291	11.2414	4.15	No	Yes	0	9	8
47	A:A:L291	A:A:S250	13.2227	3	Yes	No	0	8	6
48	A:A:L297	A:A:S250	12.9919	3	No	No	0	8	6
49	A:A:L297	A:A:V301	12.7614	2.98	No	Yes	0	8	7
50	A:A:L394	A:A:R385	75.5585	2.43	No	Yes	1	8	5
51	A:A:L394	R:R:I222	75.5961	4.28	No	No	1	8	7
52	A:A:L388	R:R:I222	75.4773	2.85	Yes	No	1	8	7
53	A:A:L388	A:A:L393	75.5901	2.77	Yes	No	0	8	8
54	A:A:L393	R:R:R115	53.9002	4.86	No	Yes	0	8	9
55	A:A:L393	R:R:I204	21.661	8.56	No	No	0	8	6
56	B:B:Y85	G:G:F61	13.7767	5.16	Yes	Yes	3	4	8
57	B:B:L51	B:B:W82	19.2723	20.5	Yes	Yes	0	9	9
58	B:B:I338	G:G:F61	16.7794	6.28	No	Yes	3	5	8
59	B:B:S84	B:B:Y85	13.7568	2.54	No	Yes	3	5	4
60	B:B:S84	B:B:W63	13.9862	4.94	No	Yes	3	5	7
61	B:B:M61	B:B:W63	16.1379	3.49	Yes	Yes	3	6	7
62	B:B:M61	B:B:S72	17.9011	3.07	Yes	Yes	3	6	9
63	B:B:G162	B:B:Y145	19.9029	7.24	No	Yes	2	9	8
64	B:B:G162	B:B:S161	20.2421	3.71	No	No	2	9	9
65	B:B:H142	B:B:S161	19.8176	13.95	Yes	No	2	9	9
66	B:B:H142	B:B:T159	11.9122	6.85	Yes	Yes	2	9	9
67	B:B:D66	B:B:R68	27.3158	2.38	No	No	0	8	5
68	B:B:D66	B:B:L69	26.8621	6.79	No	Yes	0	8	5
69	B:B:L69	B:B:Y105	15.4818	5.86	Yes	Yes	10	5	6
70	B:B:D228	B:B:S227	32.7095	5.89	Yes	No	0	9	6
71	B:B:S227	B:B:S245	54.016	3.26	No	No	0	6	9
72	B:B:H225	B:B:S245	50.5534	8.37	Yes	No	5	9	9
73	B:B:H225	B:B:T243	18.4886	8.21	Yes	Yes	5	9	8
74	B:B:D246	B:B:S227	21.6528	2.94	No	No	0	9	6
75	B:B:L198	B:B:L210	17.0134	5.54	No	Yes	5	3	5
76	B:B:D212	B:B:L198	10.6333	4.07	Yes	No	5	9	3
77	B:B:F241	B:B:T243	10.4074	2.59	Yes	Yes	5	6	8
78	B:B:F253	B:B:H225	29.0562	4.53	Yes	Yes	5	6	9
79	B:B:F241	B:B:F253	10.3955	15	Yes	Yes	5	6	6
80	B:B:C271	B:B:D290	14.1241	4.67	No	Yes	0	5	6
81	B:B:C271	B:B:Y289	13.9229	2.69	No	Yes	0	5	7
82	B:B:W297	B:B:Y264	11.0163	15.43	Yes	Yes	4	8	5
83	R:R:R115	R:R:Y201	23.2072	8.23	Yes	Yes	1	9	8
84	R:R:I230	R:R:Y201	39.9963	6.04	No	Yes	1	7	8
85	R:R:I230	R:R:W194	39.5451	4.7	No	Yes	1	7	6
86	R:R:V233	R:R:W194	39.2775	6.13	No	Yes	1	9	6
87	R:R:F237	R:R:V233	39.1299	3.93	Yes	No	1	8	9
88	R:R:F237	R:R:I101	24.2416	2.51	Yes	Yes	1	8	8
89	R:R:I101	R:R:Y66	17.7256	3.63	Yes	Yes	1	8	7
90	R:R:F97	R:R:Y66	10.9445	10.32	Yes	Yes	1	7	7
91	R:R:I204	R:R:Y201	21.6015	3.63	No	Yes	0	6	8
92	R:R:R115	R:R:Y286	27.325	3.09	Yes	Yes	1	9	9
93	R:R:L108	R:R:Y286	28.7775	9.38	Yes	Yes	1	8	9
94	R:R:D282	R:R:L108	24.1254	8.14	Yes	Yes	1	9	8
95	R:R:D282	R:R:N278	22.9183	13.46	Yes	Yes	1	9	9
96	R:R:F237	R:R:N278	22.7256	10.87	Yes	Yes	1	8	9
97	R:R:F237	R:R:T275	35.0661	9.08	Yes	No	1	8	8
98	R:R:T275	R:R:Y240	34.8255	7.49	No	Yes	1	8	6
99	R:R:Y240	R:R:Y98	11.6667	4.96	Yes	Yes	1	6	5
100	R:R:L272	R:R:Y240	10.3726	14.07	Yes	Yes	1	5	6
101	B:B:I338	B:B:L51	17.2943	4.28	No	Yes	0	5	9
102	B:B:F222	B:B:F253	17.3642	7.5	Yes	Yes	5	8	6
103	B:B:W297	B:B:Y289	11.0547	10.61	Yes	Yes	4	8	7
104	B:B:H54	B:B:S72	18.4345	11.16	Yes	Yes	3	9	9
105	B:B:M101	B:B:Y59	11.3218	8.38	Yes	Yes	2	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 8ZCF

PDB Summary
PDB	8ZCF
Class	A
SubFamily	Orphan
Type	Orphan
SubType	GPR4
Species	Homo Sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	Gs/Beta1/Gamma2
PDB Resolution	2.9
Date	2025-04-23
D.O.I.	doi.org/10.1038/s41422-025-01092-w

Net Summary
I_min	2.38
Number of Linked Nodes	857
Number of Links	1197
Number of Hubs	246
Number of Links mediated by Hubs	855
Number of Communities	16
Number of Nodes involved in Communities	363
Number of Links involved in Communities	598

Path Summary
Number Of Nodes in MetaPath	106
Number Of Links MetaPath	105
Number of Shortest Paths	6101048
Length Of Smallest Path	3
Average Path Length	30.9874
Length of Longest Path	55
Minimum Path Strength	1.28
Average Path Strength	7.28789
Maximum Path Strength	23.095
Minimum Path Correlation	0.7
Average Path Correlation	0.994598
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.77778
Average % Of Corr. Nodes	41.8943
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	61.4376
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-activating G protein-coupled receptor signaling pathway • cell communication • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • cell adhesion • regulation of cell adhesion • regulation of defense response • regulation of response to external stimulus • defense response • positive regulation of biological process • response to external stimulus • regulation of inflammatory response • positive regulation of response to stimulus • positive regulation of response to external stimulus • positive regulation of inflammatory response • regulation of response to stimulus • regulation of response to stress • response to stress • positive regulation of defense response • inflammatory response • phospholipase C-activating G protein-coupled receptor signaling pathway • positive regulation of cell communication • small GTPase-mediated signal transduction • positive regulation of signal transduction • regulation of small GTPase mediated signal transduction • regulation of signal transduction • intracellular signal transduction • Rho protein signal transduction • regulation of intracellular signal transduction • intracellular signaling cassette • positive regulation of cellular process • regulation of signaling • positive regulation of intracellular signal transduction • regulation of Rho protein signal transduction • positive regulation of Rho protein signal transduction • regulation of cell communication • positive regulation of small GTPase mediated signal transduction • positive regulation of signaling • regulation of vascular permeability • multicellular organismal process • system process • circulatory system process • vascular process in circulatory system • regulation of biological quality • blood circulation • cellular developmental process • connective tissue development • mesangial cell development • cell development • epithelial cell differentiation • renal system development • kidney vasculature development • multicellular organism development • pericyte cell differentiation • renal system vasculature development • mesangial cell differentiation • cell differentiation • anatomical structure development • nephron development • system development • epithelial cell differentiation involved in kidney development • blood vessel development • developmental process • epithelium development • animal organ development • tissue development • glomerular mesangium development • glomerular mesangial cell development • vasculature development • glomerular mesangial cell differentiation • circulatory system development • glomerulus development • epithelial cell development • cell differentiation involved in kidney development • glomerulus vasculature development • kidney development • regulation of developmental process • negative regulation of biological process • angiogenesis • regulation of vasculature development • tube morphogenesis • regulation of multicellular organismal process • regulation of anatomical structure morphogenesis • regulation of multicellular organismal development • blood vessel morphogenesis • tube development • negative regulation of blood vessel morphogenesis • negative regulation of developmental process • negative regulation of angiogenesis • negative regulation of vasculature development • anatomical structure morphogenesis • regulation of angiogenesis • anatomical structure formation involved in morphogenesis • negative regulation of multicellular organismal process • response to pH • response to abiotic stimulus • response to acidic pH • wound healing • angiogenesis involved in wound healing • response to wounding • cell periphery • cellular anatomical structure • plasma membrane • membrane • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • cell population proliferation • cellular response to nitrogen compound • response to dopamine • cellular response to dopamine • response to monoamine • response to catecholamine • adenylate cyclase-activating dopamine receptor signaling pathway • cellular response to catecholamine stimulus • G protein-coupled dopamine receptor signaling pathway • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • cellular response to monoamine stimulus • response to chemical • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • synapse • cell junction • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • sensory organ development • eye development • retina development in camera-type eye • visual system development • camera-type eye development • sensory system development • Ras protein signal transduction • synaptic signaling • cellular response to acetylcholine • cell-cell signaling • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • neuron projection • photoreceptor disc membrane • photoreceptor outer segment • plasma membrane bounded cell projection • cell projection • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome • guanyl nucleotide binding • GTP binding • nucleotide binding • guanyl ribonucleotide binding • purine ribonucleotide binding • purine ribonucleoside triphosphate binding • nucleoside phosphate binding • ion binding • purine nucleotide binding • anion binding • heterocyclic compound binding • carbohydrate derivative binding • ribonucleotide binding • small molecule binding • D1 dopamine receptor binding • signaling receptor binding • G protein-coupled receptor binding • dopamine receptor binding • G-protein beta/gamma-subunit complex binding • G protein activity • molecular function regulator activity • enzyme regulator activity • cyclase regulator activity • enzyme activator activity • cyclase activator activity • molecular function activator activity • adenylate cyclase regulator activity • adenylate cyclase activator activity • cation binding • metal ion binding • ectodermal placode morphogenesis • epidermis development • molting cycle process • hair cycle • hair follicle placode formation • ectodermal placode formation • skin development • skin epidermis development • hair follicle development • molting cycle • ectodermal placode development • hair cycle process • sensory perception of smell • response to peptide hormone • cellular response to peptide hormone stimulus • response to glucagon • cellular response to glucagon stimulus • skeletal system development • bone development • regulation of body fluid levels • homotypic cell-cell adhesion • cell activation • hemostasis • platelet aggregation • blood coagulation • cell-cell adhesion • coagulation • platelet activation • response to fluid shear stress • vascular endothelial cell response to laminar fluid shear stress • response to laminar fluid shear stress • cellular response to stress • cellular response to laminar fluid shear stress • vascular endothelial cell response to fluid shear stress • cellular response to fluid shear stress • cognition • developmental growth • growth • homeostatic process • adaptive thermogenesis • positive regulation of metabolic process • multicellular organismal-level homeostasis • regulation of cold-induced thermogenesis • cold-induced thermogenesis • temperature homeostasis • positive regulation of cold-induced thermogenesis • positive regulation of multicellular organismal process • metabolic process • regulation of metabolic process • regulation of localization • establishment of protein localization • nitrogen compound transport • regulation of hormone secretion • regulation of protein localization • regulation of peptide secretion • transport • hormone secretion • protein localization to extracellular region • localization • peptide secretion • regulation of secretion by cell • secretion by cell • amide transport • signal release • intracellular protein localization • regulation of peptide hormone secretion • regulation of transport • secretion • regulation of hormone levels • regulation of peptide transport • regulation of establishment of protein localization • establishment of protein localization to extracellular region • export from cell • regulation of protein transport • protein secretion • establishment of localization • regulation of protein secretion • regulation of secretion • peptide transport • protein transport • regulation of insulin secretion • peptide hormone secretion • macromolecule localization • hormone transport • insulin secretion • adenylate cyclase-activating adrenergic receptor signaling pathway • adrenergic receptor signaling pathway • cellular localization • establishment of localization in cell • intracellular transport • negative regulation of inflammatory response • inflammatory response to antigenic stimulus • regulation of immune system process • negative regulation of inflammatory response to antigenic stimulus • immune response • negative regulation of response to stimulus • negative regulation of immune response • regulation of inflammatory response to antigenic stimulus • negative regulation of immune system process • immune system process • negative regulation of response to external stimulus • negative regulation of defense response • regulation of immune response • positive regulation of adenylate cyclase activity • positive regulation of molecular function • regulation of molecular function • positive regulation of cyclase activity • activation of adenylate cyclase activity • regulation of adenylate cyclase activity • regulation of catalytic activity • positive regulation of catalytic activity • positive regulation of lyase activity • renal system process • chemical homeostasis • multicellular organismal-level water homeostasis • multicellular organismal-level chemical homeostasis • renal water homeostasis • Golgi apparatus subcompartment • Golgi apparatus • organelle subcompartment • trans-Golgi network membrane • endomembrane system • trans-Golgi network
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	A
Protein	G Protein α Sub unit
UniProt	P63092
Sequence	>8ZCF_Chain_A D Q R N E E K A Q R E A N K K I E K Q L Q K D K Q V Y R A T H R L L L L G K T I V K Q M R S G I F E T K F Q V D K V N F H M F D V G Q R D E R R K W I Q C F N D V T A I I F V V A S S N R L Q A L L F S I W N N W L R S V I L F L N K Q D L L A E K V L A G K S K I E D Y F P E F A R Y T T P E D A T P E P G E D P R V T R A K Y F I R D E F L R I S T A S G D G R H Y C Y P H F T C A V D T E N I R R V F N D C R D I I Q R M H L R Q Y E L L N A A K D K D T Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	B
Protein	G Protein β Sub unit
UniProt	P62873
Sequence	>8ZCF_Chain_B E L D Q L R Q E A E Q L K N Q I R D A R K A C A D A T L S Q I T N N I D P V G R I Q M R T R R T L R G H L A K I Y A M H W G T D S R L L V S A S Q D G K L I I W D S Y T T N K V H A I P L R S S W V M T C A Y A P S G N Y V A C G G L D N I C S I Y N L K T R E G N V R V S R E L A G H T G Y L S C C R F L D D N Q I V T S S G D T T C A L W D I E T G Q Q T T T F T G H T G D V M S L S L A P D T R L F V S G A C D A S A K L W D V R E G M C R Q T F T G H E S D I N A I C F F P N G N A F A T G S D D A T C R L F D L R A D Q E L M T Y S H D N I I C G I T S V S F S K S G R L L L A G Y D D F N C N V W D A L K A D R A G V L A G H D N R V S C L G V T D D G M A V A T G S W D S F L K I W N Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	G
Protein	G Protein γ Sub unit
UniProt	P59768
Sequence	>8ZCF_Chain_G T A S I A Q A R K L V E Q L K M E A N I D R I K V S K A A A D L M A Y C E A H A K E D P L L T P V P A S E N P F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

Chain	R
Protein	Receptor
UniProt	P46093
Sequence	>8ZCF_Chain_R E G C H V D S R V D H L F P P S L Y I V I G V G L P T N C L A L W A A Y R Q V Q Q R N E L G Y L M L S I A D L Y I C T L P W V D Y F H H D N W I H G P G S C K L F F I F Y T N I Y I S I A F L C C I V D R Y L A V A H P L R F R L R R V T V A V S S V V W A T E L G A N S A P L F H D E L F R D R Y N H T C F E K F P M E G W V A W M N L Y R F V G F F P W A M L S Y R L R V R G S V S T E R Q E K A K I K L A L S L A I V L V C F A P Y H V L L S R S A I Y G R P W D C G F E E R V F S A Y H S S A F T S L N C V D P I Y L V N E G A R S D A K A F V N L L L G S A K A F V L L L G I A R I L L L A L C V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	9JCP	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs-CtGq)/β1/γ2	2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.55	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCO	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCO (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.36	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC	chim(NtGi1-Gs)/β1/γ2	2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	9JCQ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	LPC		2.59	2025-07-09	doi.org/10.1038/s41421-025-00807-y
	8ZD1	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZD1 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.6	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF4	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.05	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF6 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.98	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF7	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.15	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZF9 (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFA (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.96	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFB	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.78	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFC (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.68	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFD	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	8ZFE	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVG (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVH	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.76	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9JVM	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	2.36	2025-02-26	doi.org/10.1016/j.cell.2024.12.001
	9BIP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BIP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	8ZCE	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCE (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.1	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZCF (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFU	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	3.23	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFV (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.67	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFW (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.13	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFX (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.87	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(Gs-CtGq)/β1/γ2	2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JFZ (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi2-G13)/β1/γ2	3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9JHP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.35	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	9LGM (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.84	2025-04-23	doi.org/10.1038/s41422-025-01092-w
	8ZFZ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31 (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8Z3M	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs-CtGq)/β1/γ2	2.9	2025-04-23	To be published
	8Z3M (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.9	2025-04-23	To be published
	8Z3Q	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-04-23	To be published
	8Z3Q (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.76	2025-04-23	To be published
	8Z65	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-04-23	To be published
	8Z65 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.98	2025-04-23	To be published
	8Z66	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.06	2025-04-23	To be published
	8Z67	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-04-23	To be published
	9LMO	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	-	3.2	2025-07-09	To be published
	9LMP	A	Orphan	Orphan	GPR4	Homo sapiens	NE52-QQ57	-	-	2.65	2025-07-02	To be published
	8Z3Y	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	3.2	2025-06-04	To be published
	8Z3Y (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		3.2	2025-06-04	To be published
	8Z9P	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gi1/β1/γ2	2.5	2025-07-09	To be published
	8Z9P (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.5	2025-07-09	To be published
	9IV6	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	chim(NtGi1-Gs)/β1/γ2	2.71	2025-07-30	To be published
	9IV6 (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.71	2025-07-30	To be published
	8Z9O	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.4	2025-07-16	To be published
	8Z9O (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.4	2025-07-16	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

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