psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:G14	R:R:S17	3.71	No	Yes	0	2	4
2	R:R:D16	R:R:L15	6.79	No	No	0	5	5
3	R:R:D16	R:R:P273	3.22	No	No	0	5	3
4	R:R:S17	R:R:Y77	3.82	Yes	Yes	1	4	5
5	R:R:H165	R:R:S17	4.18	Yes	Yes	1	3	4
6	R:R:H276	R:R:S17	11.16	Yes	Yes	1	5	4
7	R:R:L19	R:R:P20	3.28	No	Yes	0	5	5
8	R:R:L19	R:R:L23	4.15	No	No	0	5	4
9	R:R:P20	R:R:P21	7.79	Yes	No	1	5	6
10	R:R:P20	R:R:Y24	5.56	Yes	Yes	1	5	8
11	R:R:P20	R:R:Y77	8.34	Yes	Yes	1	5	5
12	R:R:A280	R:R:P20	3.74	No	Yes	1	4	5
13	R:R:P21	R:R:Y77	5.56	No	Yes	1	6	5
14	R:R:V27	R:R:Y24	2.52	No	Yes	0	7	8
15	R:R:T74	R:R:Y24	12.48	No	Yes	0	7	8
16	R:R:Y24	R:R:Y77	1.99	Yes	Yes	1	8	5
17	R:R:F167	R:R:Y24	6.19	Yes	Yes	1	3	8
18	R:R:A280	R:R:Y24	2.67	No	Yes	1	4	8
19	R:R:T283	R:R:Y24	12.48	No	Yes	0	7	8
20	R:R:F28	R:R:I67	5.02	No	No	0	7	5
21	R:R:L30	R:R:T29	2.95	No	No	0	5	4
22	R:R:L32	R:R:P33	3.28	No	No	0	5	4
23	R:R:L32	R:R:L64	2.77	No	Yes	0	5	7
24	R:R:I67	R:R:L32	4.28	No	No	0	5	5
25	R:R:A34	R:R:P290	3.74	No	No	0	7	9
26	R:R:D63	R:R:N35	10.77	Yes	No	0	9	9
27	R:R:L64	R:R:N35	2.75	Yes	No	0	7	9
28	R:R:N35	R:R:P290	8.15	No	No	0	9	9
29	R:R:E303	R:R:L37	21.2	Yes	No	0	6	5
30	R:R:A38	R:R:S60	3.42	No	No	0	9	9
31	R:R:L39	R:R:L57	6.92	Yes	No	0	7	5
32	R:R:L39	R:R:S60	9.01	Yes	No	0	7	9
33	R:R:L39	R:R:L61	4.15	Yes	No	0	7	6
34	R:R:L39	R:R:L64	4.15	Yes	Yes	0	7	7
35	R:R:K306	R:R:W40	26.69	Yes	No	0	6	3
36	R:R:A42	R:R:G53	1.95	No	No	0	6	7
37	R:R:V46	R:R:W43	6.13	No	No	0	5	3
38	R:R:R47	R:R:W43	6	No	No	0	6	3
39	R:R:K306	R:R:L44	2.82	Yes	No	0	6	4
40	R:R:Q45	R:R:R50	14.02	No	No	0	5	7
41	R:R:I131	R:R:V46	3.07	No	No	0	3	5
42	R:R:K48	R:R:R47	2.48	No	No	0	5	6
43	R:R:E51	R:R:P130	4.72	No	No	0	6	5
44	R:R:D114	R:R:L52	5.43	No	No	0	8	7
45	R:R:V54	R:R:Y55	3.79	No	Yes	0	6	7
46	R:R:I131	R:R:V54	6.14	No	No	0	3	6
47	R:R:C110	R:R:Y55	2.69	No	Yes	0	6	7
48	R:R:V111	R:R:Y55	2.52	No	Yes	0	8	7
49	R:R:D114	R:R:Y55	6.9	No	Yes	0	8	7
50	R:R:A134	R:R:Y55	5.34	No	Yes	0	8	7
51	R:R:V137	R:R:Y55	3.79	No	Yes	0	5	7
52	R:R:L56	R:R:Y293	16.41	No	No	0	8	9
53	R:R:F107	R:R:N58	4.83	Yes	No	2	7	9
54	R:R:N58	R:R:S138	10.43	No	No	2	9	7
55	R:R:N58	R:R:W142	3.39	No	Yes	2	9	9
56	R:R:D63	R:R:L59	4.07	Yes	No	0	9	9
57	R:R:F107	R:R:L59	12.18	Yes	No	0	7	9
58	R:R:D289	R:R:L59	6.79	No	No	0	9	9
59	R:R:D63	R:R:S62	2.94	Yes	Yes	0	9	8
60	R:R:S62	R:R:V103	3.23	Yes	Yes	2	8	7
61	R:R:F107	R:R:S62	3.96	Yes	Yes	2	7	8
62	R:R:S62	R:R:W142	2.47	Yes	Yes	2	8	9
63	R:R:C286	R:R:D63	10.89	No	Yes	0	7	9
64	R:R:L66	R:R:V96	2.98	No	No	0	7	5
65	R:R:L66	R:R:N100	17.85	No	No	0	7	9
66	R:R:C286	R:R:I67	3.27	No	No	0	7	5
67	R:R:A69	R:R:P72	1.87	No	No	0	6	6
68	R:R:L70	R:R:T74	5.9	No	No	0	8	7
69	R:R:P71	R:R:P72	5.84	No	No	0	9	6
70	R:R:W73	R:R:Y77	1.93	Yes	Yes	1	6	5
71	R:R:F93	R:R:W73	15.03	Yes	Yes	1	5	6
72	R:R:F97	R:R:W73	40.09	No	Yes	0	7	6
73	R:R:F167	R:R:W73	10.02	Yes	Yes	1	3	6
74	R:R:C168	R:R:W73	10.45	No	Yes	1	9	6
75	R:R:D75	R:R:Y76	2.3	No	Yes	0	4	6
76	R:R:D75	R:R:R79	8.34	No	No	0	4	4
77	R:R:D81	R:R:Y76	12.64	No	Yes	1	4	6
78	R:R:G84	R:R:Y76	4.35	No	Yes	1	3	6
79	R:R:A89	R:R:Y76	5.34	No	Yes	1	5	6
80	R:R:F93	R:R:Y76	19.6	Yes	Yes	1	5	6
81	R:R:C168	R:R:Y76	8.06	No	Yes	1	9	6
82	R:R:H165	R:R:Y77	4.36	Yes	Yes	1	3	5
83	R:R:F167	R:R:Y77	43.32	Yes	Yes	1	3	5
84	R:R:H276	R:R:Y77	21.78	Yes	Yes	1	5	5
85	R:R:L78	R:R:R79	2.43	No	No	0	5	4
86	R:R:D81	R:R:R79	7.15	No	No	0	4	4
87	R:R:H165	R:R:R80	9.03	Yes	No	0	3	3
88	R:R:D81	R:R:G84	5.03	No	No	1	4	3
89	R:R:V82	R:R:W83	2.45	No	No	0	4	8
90	R:R:D161	R:R:V82	7.3	Yes	No	1	1	4
91	R:R:T166	R:R:V82	11.11	Yes	No	1	5	4
92	R:R:P87	R:R:Y85	2.78	No	No	4	3	6
93	R:R:G88	R:R:Y85	4.35	No	No	4	2	6
94	R:R:G86	R:R:P87	4.06	No	No	0	8	3
95	R:R:G88	R:R:P87	2.03	No	No	4	2	3
96	R:R:A89	R:R:F93	4.16	No	Yes	1	5	5
97	R:R:C90	R:R:I158	3.27	No	No	0	9	4
98	R:R:C168	R:R:F93	12.57	No	Yes	1	9	5
99	R:R:G94	R:R:Y169	4.35	No	No	0	6	3
100	R:R:F95	R:R:T99	3.89	No	No	0	5	4
101	R:R:F97	R:R:V96	2.62	No	No	0	7	5
102	R:R:F97	R:R:L279	2.44	No	Yes	0	7	6
103	R:R:Y102	R:R:Y98	10.92	Yes	No	3	7	5
104	R:R:N149	R:R:Y98	12.79	No	No	0	6	5
105	R:R:R186	R:R:Y98	7.2	Yes	No	3	6	5
106	R:R:L101	R:R:Y102	5.86	No	Yes	0	7	7
107	R:R:L101	R:R:Y238	4.69	No	Yes	0	7	8
108	R:R:R186	R:R:Y102	11.32	Yes	Yes	3	6	7
109	R:R:G190	R:R:Y102	5.79	No	Yes	0	6	7
110	R:R:G104	R:R:V103	3.68	No	Yes	0	9	7
111	R:R:F107	R:R:V103	10.49	Yes	Yes	2	7	7
112	R:R:V103	R:R:W142	2.45	Yes	Yes	2	7	9
113	R:R:E145	R:R:V103	11.41	Yes	Yes	2	7	7
114	R:R:A106	R:R:E145	3.02	No	Yes	0	6	7
115	R:R:F107	R:R:I141	2.51	Yes	No	0	7	6
116	R:R:F107	R:R:W142	6.01	Yes	Yes	2	7	9
117	R:R:D289	R:R:L108	4.07	No	No	0	9	8
118	R:R:S109	R:R:V197	4.85	No	No	0	7	6
119	R:R:C110	R:R:I141	3.27	No	No	0	6	6
120	R:R:R115	R:R:V111	2.62	Yes	No	0	9	8
121	R:R:R115	R:R:S112	5.27	Yes	No	0	9	9
122	R:R:M198	R:R:S112	3.07	Yes	No	0	7	9
123	R:R:C201	R:R:S112	3.44	No	No	0	7	9
124	R:R:A113	R:R:C201	1.81	No	No	0	5	7
125	R:R:L226	R:R:R115	3.64	No	Yes	0	7	9
126	R:R:A227	R:R:R115	5.53	No	Yes	0	7	9
127	R:R:L230	R:R:R115	9.72	No	Yes	0	7	9
128	R:R:L117	R:R:Y116	3.52	No	Yes	6	6	8
129	R:R:A120	R:R:Y116	2.67	No	Yes	0	7	8
130	R:R:H121	R:R:Y116	3.27	Yes	Yes	6	6	8
131	R:R:C201	R:R:Y116	6.72	No	Yes	0	7	8
132	R:R:H121	R:R:L117	7.71	Yes	No	6	6	6
133	R:R:L117	R:R:R129	2.43	No	No	0	6	7
134	R:R:L205	R:R:V119	4.47	No	Yes	0	8	8
135	R:R:L209	R:R:V119	2.98	No	Yes	0	8	8
136	R:R:A120	R:R:A208	1.79	No	No	0	7	5
137	R:R:H121	R:R:P122	13.73	Yes	No	0	6	8
138	R:R:F125	R:R:H121	10.18	No	Yes	0	5	6
139	R:R:H121	R:R:P126	3.05	Yes	No	0	6	5
140	R:R:F125	R:R:R124	3.21	No	No	0	5	4
141	R:R:F125	R:R:R129	5.34	No	No	0	5	7
142	R:R:R129	R:R:S133	5.27	No	No	0	7	1
143	R:R:P130	R:R:S133	1.78	No	No	0	5	1
144	R:R:S138	R:R:W142	2.47	No	Yes	2	7	9
145	R:R:L140	R:R:M143	2.83	No	No	0	3	4
146	R:R:E145	R:R:I141	8.2	Yes	No	0	7	6
147	R:R:E145	R:R:W142	3.27	Yes	Yes	2	7	9
148	R:R:A150	R:R:N149	3.13	No	No	0	3	6
149	R:R:L153	R:R:N149	5.49	No	No	0	4	6
150	R:R:A150	R:R:P151	1.87	No	No	0	3	8
151	R:R:P151	R:R:P152	5.84	No	No	0	8	4
152	R:R:A157	R:R:L153	6.3	No	No	0	4	4
153	R:R:E156	R:R:L154	6.63	No	No	0	6	4
154	R:R:D161	R:R:T166	17.34	Yes	Yes	1	1	5
155	R:R:D161	R:R:E170	3.9	Yes	Yes	1	1	6
156	R:R:H165	R:R:H276	8.36	Yes	Yes	1	3	5
157	R:R:E170	R:R:T166	7.06	Yes	Yes	1	6	5
158	R:R:F272	R:R:T166	3.89	Yes	Yes	1	4	5
159	R:R:E170	R:R:F167	3.5	Yes	Yes	1	6	3
160	R:R:F167	R:R:H276	15.84	Yes	Yes	1	3	5
161	R:R:F167	R:R:L279	12.18	Yes	Yes	1	3	6
162	R:R:R186	R:R:Y169	4.12	Yes	No	0	6	3
163	R:R:E170	R:R:F272	8.16	Yes	Yes	1	6	4
164	R:R:E170	R:R:H276	6.15	Yes	Yes	1	6	5
165	R:R:E170	R:R:L279	5.3	Yes	Yes	1	6	6
166	R:R:P173	R:R:S171	5.34	No	No	0	6	4
167	R:R:F252	R:R:L174	14.61	No	No	0	4	3
168	R:R:G176	R:R:S175	1.86	No	Yes	0	1	3
169	R:R:A179	R:R:S175	3.42	No	Yes	0	3	3
170	R:R:A180	R:R:S175	3.42	No	Yes	0	3	3
171	R:R:F252	R:R:S175	5.28	No	Yes	0	4	3
172	R:R:G176	R:R:R177	4.5	No	No	0	1	1
173	R:R:A180	R:R:L253	4.73	No	No	0	3	4
174	R:R:L181	R:R:L253	2.77	No	No	0	3	4
175	R:R:N183	R:R:R186	8.44	No	Yes	3	5	6
176	R:R:L245	R:R:N183	13.73	No	No	3	6	5
177	R:R:N183	R:R:S249	5.96	No	No	0	5	5
178	R:R:S249	R:R:V184	3.23	No	No	0	5	4
179	R:R:L250	R:R:V184	2.98	No	No	0	4	4
180	R:R:L245	R:R:R186	3.64	No	Yes	3	6	6
181	R:R:L188	R:R:V187	5.96	No	No	0	4	6
182	R:R:H242	R:R:V187	11.07	No	No	0	8	6
183	R:R:L246	R:R:V187	2.98	No	No	0	6	6
184	R:R:F191	R:R:L192	4.87	Yes	No	0	9	4
185	R:R:F191	R:R:W195	8.02	Yes	Yes	0	9	6
186	R:R:F191	R:R:G239	4.52	Yes	No	0	9	6
187	R:R:F191	R:R:H242	15.84	Yes	No	0	9	8
188	R:R:L193	R:R:P194	3.28	No	No	0	5	9
189	R:R:M199	R:R:W195	8.14	No	Yes	0	4	6
190	R:R:L235	R:R:W195	6.83	No	Yes	0	5	6
191	R:R:M198	R:R:P231	3.35	Yes	No	0	7	7
192	R:R:A234	R:R:M198	3.22	No	Yes	0	9	7
193	R:R:M199	R:R:Y202	8.38	No	Yes	0	4	9
194	R:R:M199	R:R:P231	5.03	No	No	0	4	7
195	R:R:A203	R:R:Y202	8.01	No	Yes	0	3	9
196	R:R:L206	R:R:Y202	4.69	No	Yes	0	5	9
197	R:R:L228	R:R:Y202	14.07	No	Yes	0	4	9
198	R:R:L206	R:R:R224	9.72	No	No	0	5	5
199	R:R:L226	R:R:L292	4.15	No	No	0	7	7
200	R:R:L226	R:R:L295	2.77	No	No	0	7	8
201	R:R:G229	R:R:L292	3.42	No	No	0	5	7
202	R:R:L230	R:R:L292	4.15	No	No	0	7	7
203	R:R:L235	R:R:L236	2.77	No	No	0	5	5
204	R:R:C237	R:R:Y238	10.75	No	Yes	5	8	8
205	R:R:C237	R:R:N285	11.02	No	No	5	8	9
206	R:R:A282	R:R:Y238	2.67	No	Yes	0	8	8
207	R:R:N285	R:R:Y238	15.12	No	Yes	5	9	8
208	R:R:G239	R:R:P240	4.06	No	No	0	6	9
209	R:R:P240	R:R:S278	1.78	No	No	0	9	7
210	R:R:L281	R:R:P240	4.93	No	No	0	7	9
211	R:R:S278	R:R:Y241	7.63	No	No	0	7	7
212	R:R:L279	R:R:Y241	5.86	Yes	No	0	6	7
213	R:R:L244	R:R:Y275	7.03	No	Yes	0	5	6
214	R:R:L246	R:R:L250	5.54	No	No	0	6	4
215	R:R:L247	R:R:V251	2.98	No	No	0	5	4
216	R:R:R248	R:R:Y275	5.14	No	Yes	0	5	6
217	R:R:E268	R:R:Y275	2.24	No	Yes	0	4	6
218	R:R:L271	R:R:Y275	4.69	No	Yes	0	4	6
219	R:R:F272	R:R:P273	4.33	Yes	No	0	4	3
220	R:R:F272	R:R:Y275	4.13	Yes	Yes	0	4	6
221	R:R:F272	R:R:H276	4.53	Yes	Yes	1	4	5
222	R:R:L284	R:R:L287	4.15	No	No	0	5	6
223	R:R:D289	R:R:P290	3.22	No	No	0	9	9
224	R:R:C294	R:R:E303	4.56	No	Yes	0	6	6
225	R:R:A296	R:R:P298	1.87	No	No	0	6	6
226	R:R:C297	R:R:P298	1.88	No	No	0	7	6
227	R:R:G302	R:R:R301	7.51	No	No	0	4	8
228	R:R:G302	R:R:K306	5.23	No	Yes	0	4	6
229	R:R:E303	R:R:K306	4.05	Yes	Yes	0	6	6
230	R:R:V304	R:R:V308	4.81	No	No	0	6	4
231	R:R:V307	R:R:V308	4.81	No	No	0	3	4
232	R:R:G94	R:R:I158	1.76	No	No	0	6	4
233	R:R:G31	R:R:L287	1.71	No	No	0	8	6
234	R:R:G127	R:R:L123	1.71	No	No	0	4	5
235	R:R:A118	R:R:V119	1.7	No	Yes	0	8	8
236	R:R:A288	R:R:V233	1.7	No	No	0	6	6
237	R:R:M198	R:R:P194	1.68	Yes	No	0	7	9
238	R:R:L70	R:R:P71	1.64	No	No	0	8	9
239	R:R:E156	R:R:G155	1.64	No	No	0	6	3
240	R:R:V119	R:R:V223	1.6	Yes	No	0	8	7
241	R:R:A42	R:R:L56	1.58	No	No	0	6	8
242	R:R:A42	R:R:L57	1.58	No	No	0	6	5
243	R:R:A120	R:R:L205	1.58	No	No	0	7	8
244	R:R:A227	R:R:L205	1.58	No	No	0	7	8
245	R:R:A274	R:R:L244	1.58	No	No	0	4	5
246	R:R:A288	R:R:N285	1.56	No	No	0	6	9
247	R:R:M198	R:R:S109	1.53	Yes	No	0	7	7
248	R:R:A41	R:R:E303	1.51	No	Yes	0	7	6
249	R:R:G178	R:R:R177	1.5	No	No	0	3	1
250	R:R:G204	R:R:R207	1.5	No	No	0	4	4
251	R:R:L287	R:R:V27	1.49	No	No	0	6	7
252	R:R:L37	R:R:V307	1.49	No	No	0	5	3
253	R:R:L253	R:R:V184	1.49	No	No	0	4	4
254	R:R:L250	R:R:V254	1.49	No	No	0	4	1
255	R:R:G86	R:R:W83	1.41	No	No	0	8	8
256	R:R:L144	R:R:M143	1.41	No	No	0	4	4
257	R:R:G196	R:R:W195	1.41	No	Yes	0	2	6
258	R:R:L26	R:R:L30	1.38	No	No	0	4	5
259	R:R:L36	R:R:L64	1.38	No	Yes	0	3	7
260	R:R:L65	R:R:L66	1.38	No	No	0	7	7
261	R:R:A305	R:R:R301	1.38	No	No	0	5	8
262	R:R:C294	R:R:Y293	1.34	No	No	0	6	9
263	R:R:R80	R:R:V18	1.31	No	No	0	3	4
264	R:R:F95	R:R:V96	1.31	No	No	0	5	5
265	R:R:I131	R:R:R132	1.25	No	No	0	3	4
266	R:R:F93	R:R:L92	1.22	Yes	No	0	5	5
267	R:R:D161	R:R:Y172	1.15	Yes	No	0	1	5
268	R:R:R160	R:R:Y172	1.03	No	No	0	1	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:S17	5.7175	4	1	4
2	R:R:P20	5.742	5	1	5
3	R:R:Y24	6.27	7	1	8
4	R:R:L39	6.0575	4	0	7
5	R:R:Y55	4.17167	6	0	7
6	R:R:S62	3.15	4	2	8
7	R:R:D63	7.1675	4	0	9
8	R:R:L64	2.7625	4	0	7
9	R:R:W73	15.504	5	1	6
10	R:R:Y76	8.715	6	1	6
11	R:R:Y77	11.3875	8	1	5
12	R:R:F93	10.516	5	1	5
13	R:R:Y102	8.4725	4	3	7
14	R:R:V103	6.252	5	2	7
15	R:R:F107	6.66333	6	2	7
16	R:R:R115	5.356	5	0	9
17	R:R:Y116	4.045	4	6	8
18	R:R:V119	2.6875	4	0	8
19	R:R:H121	7.588	5	6	6
20	R:R:W142	3.34333	6	2	9
21	R:R:E145	6.475	4	2	7
22	R:R:D161	7.4225	4	1	1
23	R:R:H165	6.4825	4	1	3
24	R:R:T166	9.85	4	1	5
25	R:R:F167	15.175	6	1	3
26	R:R:E170	5.67833	6	1	6
27	R:R:S175	3.495	4	0	3
28	R:R:R186	6.944	5	3	6
29	R:R:F191	8.3125	4	0	9
30	R:R:W195	6.1	4	0	6
31	R:R:M198	2.57	5	0	7
32	R:R:Y202	8.7875	4	0	9
33	R:R:Y238	8.3075	4	5	8
34	R:R:F272	5.008	5	1	4
35	R:R:Y275	4.646	5	0	6
36	R:R:H276	11.3033	6	1	5
37	R:R:L279	6.445	4	1	6
38	R:R:E303	7.83	4	0	6
39	R:R:K306	9.6975	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:D63	R:R:L59	31.5119	4.07	Yes	No	0	9	9
2	R:R:F107	R:R:L59	36.3453	12.18	Yes	No	0	7	9
3	R:R:F107	R:R:I141	74.4405	2.51	Yes	No	0	7	6
4	R:R:C110	R:R:I141	80.5023	3.27	No	No	0	6	6
5	R:R:C110	R:R:Y55	81.066	2.69	No	Yes	0	6	7
6	R:R:V111	R:R:Y55	87.0057	2.52	No	Yes	0	8	7
7	R:R:R115	R:R:V111	87.4685	2.62	Yes	No	0	9	8
8	R:R:R115	R:R:S112	91.856	5.27	Yes	No	0	9	9
9	R:R:M198	R:R:S112	97.5896	3.07	Yes	No	0	7	9
10	R:R:M198	R:R:P231	98.7506	3.35	Yes	No	0	7	7
11	R:R:M199	R:R:P231	98.9063	5.03	No	No	0	4	7
12	R:R:M199	R:R:W195	99.6635	8.14	No	Yes	0	4	6
13	R:R:F191	R:R:W195	100	8.02	Yes	Yes	0	9	6
14	R:R:F191	R:R:G239	95.276	4.52	Yes	No	0	9	6
15	R:R:G239	R:R:P240	94.9773	4.06	No	No	0	6	9
16	R:R:P240	R:R:S278	94.3547	1.78	No	No	0	9	7
17	R:R:S278	R:R:Y241	94.0308	7.63	No	No	0	7	7
18	R:R:L279	R:R:Y241	93.6985	5.86	Yes	No	0	6	7
19	R:R:F167	R:R:L279	43.8331	12.18	Yes	Yes	1	3	6
20	R:R:D63	R:R:S62	32.7865	2.94	Yes	Yes	0	9	8
21	R:R:F107	R:R:S62	32.2943	3.96	Yes	Yes	2	7	8
22	R:R:E170	R:R:L279	27.7638	5.3	Yes	Yes	1	6	6
23	R:R:D63	R:R:N35	52.768	10.77	Yes	No	0	9	9
24	R:R:L64	R:R:N35	51.2578	2.75	Yes	No	0	7	9
25	R:R:C294	R:R:E303	24.4616	4.56	No	Yes	0	6	6
26	R:R:C294	R:R:Y293	26.4807	1.34	No	No	0	6	9
27	R:R:L56	R:R:Y293	28.2686	16.41	No	No	0	8	9
28	R:R:A42	R:R:L56	30.2751	1.58	No	No	0	6	8
29	R:R:A42	R:R:L57	34.2209	1.58	No	No	0	6	5
30	R:R:L39	R:R:L57	36.1812	6.92	Yes	No	0	7	5
31	R:R:L39	R:R:L64	43.9382	4.15	Yes	Yes	0	7	7
32	R:R:E303	R:R:K306	12.4558	4.05	Yes	Yes	0	6	6
33	R:R:C201	R:R:Y116	14.9209	6.72	No	Yes	0	7	8
34	R:R:C201	R:R:S112	17.2093	3.44	No	No	0	7	9
35	R:R:F97	R:R:W73	18.9214	40.09	No	Yes	0	7	6
36	R:R:F93	R:R:W73	22.4382	15.03	Yes	Yes	1	5	6
37	R:R:C168	R:R:W73	18.3577	10.45	No	Yes	1	9	6
38	R:R:D75	R:R:Y76	12.3086	2.3	No	Yes	0	4	6
39	R:R:F93	R:R:Y76	16.3848	19.6	Yes	Yes	1	5	6
40	R:R:C168	R:R:Y76	16.3554	8.06	No	Yes	1	9	6
41	R:R:D81	R:R:Y76	12.3044	12.64	No	Yes	1	4	6
42	R:R:V82	R:R:W83	11.3537	2.45	No	No	0	4	8
43	R:R:N183	R:R:R186	25.0925	8.44	No	Yes	3	5	6
44	R:R:N183	R:R:S249	27.4188	5.96	No	No	0	5	5
45	R:R:S249	R:R:V184	28.5252	3.23	No	No	0	5	4
46	R:R:L250	R:R:V184	40.1397	2.98	No	No	0	4	4
47	R:R:L246	R:R:L250	42.142	5.54	No	No	0	6	4
48	R:R:L246	R:R:V187	43.1306	2.98	No	No	0	6	6
49	R:R:H242	R:R:V187	45.0825	11.07	No	No	0	8	6
50	R:R:F191	R:R:H242	46.0458	15.84	Yes	No	0	9	8
51	R:R:R186	R:R:Y102	11.1181	11.32	Yes	Yes	3	6	7
52	R:R:A180	R:R:L253	10.159	4.73	No	No	0	3	4
53	R:R:L253	R:R:V184	12.6115	1.49	No	No	0	4	4
54	R:R:F167	R:R:Y24	16.1198	6.19	Yes	Yes	1	3	8
55	R:R:F97	R:R:L279	24.1334	2.44	No	Yes	0	7	6
56	R:R:F167	R:R:W73	22.211	10.02	Yes	Yes	1	3	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 9JVM

PDB Summary
PDB	9JVM
Class	A
SubFamily	Orphan
Type	Orphan
SubType	GPR4
Species	Xenopus tropicalis
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	2.36
Date	2025-02-26
D.O.I.	10.1016/j.cell.2024.12.001

Net Summary
I_min	1.78
Number of Linked Nodes	239
Number of Links	268
Number of Hubs	39
Number of Links mediated by Hubs	146
Number of Communities	6
Number of Nodes involved in Communities	43
Number of Links involved in Communities	67

Path Summary
Number Of Nodes in MetaPath	57
Number Of Links MetaPath	56
Number of Shortest Paths	42654
Length Of Smallest Path	3
Average Path Length	18.7355
Length of Longest Path	41
Minimum Path Strength	1.09
Average Path Strength	5.94038
Maximum Path Strength	27.75
Minimum Path Correlation	0.7
Average Path Correlation	0.930085
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	2.94118
Average % Of Corr. Nodes	37.4004
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	39.5908
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	A0A6I8PUB9
Sequence	>9JVM_Chain_R G L D S V L P P S L Y A L V F T L G L P A N L L A L W A A W L Q V R K G R E L G V Y L L N L S L S D L L L I C A L P P W T D Y Y L R R D V W G Y G P G A C R L F G F V F Y T N L Y V G A A F L S C V S A D R Y L A V A H P L R F P G A R P I R S A A A V S A L I W M L E L A A N A P P L L G E A I H R D H T F C Y E S Y P L S G R G A A L A N V G R V L A G F L L P W G V M M L C Y A G L L R A L R V R R L A L G L P C V A L L C Y G P Y H A L L L L R S L V F L V E E R L F P A Y H A S L A L A T L N C L A D P A L Y C L A C P G A R G E V A K V V Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8ZFE	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFD	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFB	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.78	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF7	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.15	2025-02-26	10.1016/j.cell.2024.12.001
	9JVG	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.76	2025-02-26	10.1016/j.cell.2024.12.001
	9JVG (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.76	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFC	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.68	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFC (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.68	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFA	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.96	2025-02-26	10.1016/j.cell.2024.12.001
	8ZFA (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.96	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF9	A	Orphan	Orphan	GPR4	Mus musculus	-	-	chim(NtGi1-Gs)/β1/γ2	2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF9 (No Gprot)	A	Orphan	Orphan	GPR4	Mus musculus	-	-		2.56	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF6	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.98	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF6 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.98	2025-02-26	10.1016/j.cell.2024.12.001
	8ZD1	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	chim(NtGi1-Gs)/β1/γ2	2.6	2025-02-26	10.1016/j.cell.2024.12.001
	8ZD1 (No Gprot)	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-		2.6	2025-02-26	10.1016/j.cell.2024.12.001
	8ZF4	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	3.05	2025-02-26	10.1016/j.cell.2024.12.001
	9J31	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9J31 (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.05	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	8ZFZ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.3	2025-01-22	doi.org/10.1038/s41467-025-55901-2
	9BIP	A	Orphan	Orphan	GPR4	Homo sapiens	-	-	Gs/β1/γ2	2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	9BIP (No Gprot)	A	Orphan	Orphan	GPR4	Homo sapiens	-	-		2.8	2025-01-22	doi.org/10.1016/j.cell.2024.11.036
	8ZFJ	A	Orphan	Orphan	GPR4	Danio rerio	-	-	chim(NtGi1-Gs)/β1/γ2	3.1	2024-08-07	To be published
	8ZFJ (No Gprot)	A	Orphan	Orphan	GPR4	Danio rerio	-	-		3.1	2024-08-07	To be published
	9JVM	A	Orphan	Orphan	GPR4	Xenopus tropicalis	-	-	-	2.36	2025-02-26	10.1016/j.cell.2024.12.001
	9JVH	A	Orphan	Orphan	GPR4	Mus musculus	-	-	-	2.76	2025-02-26	10.1016/j.cell.2024.12.001

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9JVM.zip

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