psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:M40	R:R:W313	6.98	No	No	0	6	5
2	R:R:V44	R:R:V87	4.81	No	No	0	6	7
3	R:R:D79	R:R:I47	4.2	No	Yes	2	9	8
4	R:R:G83	R:R:I47	3.53	No	Yes	0	7	8
5	R:R:I47	R:R:S319	6.19	Yes	Yes	2	8	9
6	R:R:L84	R:R:V48	8.94	No	No	0	5	6
7	R:R:F49	R:R:L53	13.4	No	Yes	0	4	6
8	R:R:G50	R:R:P323	4.06	No	No	0	8	9
9	R:R:D79	R:R:N51	13.46	No	No	0	9	9
10	R:R:F336	R:R:L53	3.65	Yes	Yes	0	7	6
11	R:R:L339	R:R:L53	4.15	Yes	Yes	0	6	6
12	R:R:L340	R:R:L53	4.15	No	Yes	0	6	6
13	R:R:A76	R:R:V54	3.39	No	No	0	9	9
14	R:R:I55	R:R:T73	4.56	No	No	0	7	6
15	R:R:A76	R:R:I55	3.25	No	No	0	9	7
16	R:R:I55	R:R:L80	2.85	No	No	0	7	7
17	R:R:L339	R:R:T56	2.95	Yes	No	0	6	5
18	R:R:I58	R:R:Y70	3.63	No	No	0	7	4
19	R:R:I58	R:R:T73	6.08	No	No	0	7	6
20	R:R:F61	R:R:L64	4.87	No	No	0	6	8
21	R:R:E338	R:R:F61	8.16	No	No	0	4	6
22	R:R:F61	R:R:L339	6.09	No	Yes	0	6	6
23	R:R:E62	R:R:Q65	8.92	No	No	0	6	8
24	R:R:A335	R:R:L64	4.73	No	No	0	7	8
25	R:R:N69	R:R:T66	11.7	No	No	0	9	7
26	R:R:F71	R:R:V67	3.93	Yes	No	1	8	6
27	R:R:D130	R:R:V67	4.38	Yes	No	1	8	6
28	R:R:R131	R:R:T68	6.47	Yes	No	0	9	8
29	R:R:L275	R:R:T68	2.95	No	No	0	8	8
30	R:R:F332	R:R:N69	6.04	Yes	No	0	9	9
31	R:R:K147	R:R:Y70	7.17	No	No	4	1	4
32	R:R:R151	R:R:Y70	15.43	No	No	4	3	4
33	R:R:F71	R:R:V126	5.24	Yes	No	0	8	7
34	R:R:F71	R:R:I127	5.02	Yes	No	0	8	9
35	R:R:D130	R:R:F71	4.78	Yes	Yes	1	8	8
36	R:R:F71	R:R:I153	6.28	Yes	No	0	8	6
37	R:R:F71	R:R:I154	6.28	Yes	No	0	8	8
38	R:R:I72	R:R:Y326	7.25	No	Yes	0	8	9
39	R:R:L75	R:R:S74	3	No	No	0	9	9
40	R:R:I154	R:R:S74	3.1	No	No	0	8	9
41	R:R:S74	R:R:W158	3.71	No	No	0	9	9
42	R:R:L75	R:R:T123	4.42	No	No	0	9	8
43	R:R:L124	R:R:L75	4.15	No	No	0	8	9
44	R:R:C77	R:R:W158	5.22	No	No	0	6	9
45	R:R:D79	R:R:S319	8.83	No	Yes	2	9	9
46	R:R:C116	R:R:V81	3.42	No	No	0	7	7
47	R:R:M82	R:R:V86	7.61	Yes	No	2	7	7
48	R:R:C116	R:R:M82	4.86	No	Yes	0	7	7
49	R:R:M82	R:R:Y316	8.38	Yes	Yes	2	7	6
50	R:R:M82	R:R:S319	4.6	Yes	Yes	2	7	9
51	R:R:G83	R:R:V87	3.68	No	No	0	7	7
52	R:R:D113	R:R:V86	10.22	No	No	2	7	7
53	R:R:V86	R:R:Y316	3.79	No	Yes	2	7	6
54	R:R:P88	R:R:V87	3.53	No	No	0	8	7
55	R:R:F89	R:R:W109	7.02	No	No	0	5	5
56	R:R:G90	R:R:W109	4.22	No	No	0	7	5
57	R:R:T110	R:R:W109	4.85	No	No	0	4	5
58	R:R:D113	R:R:Y316	4.6	No	Yes	2	7	6
59	R:R:T118	R:R:V114	6.35	Yes	No	0	6	5
60	R:R:L115	R:R:S161	3	No	No	0	5	8
61	R:R:V117	R:R:W286	13.48	No	Yes	0	6	8
62	R:R:S161	R:R:T118	4.8	No	Yes	0	8	6
63	R:R:T118	R:R:T164	3.14	Yes	No	0	6	5
64	R:R:S207	R:R:T118	7.99	No	Yes	0	5	6
65	R:R:A119	R:R:S161	3.42	No	No	0	7	8
66	R:R:F282	R:R:S120	7.93	Yes	No	0	9	9
67	R:R:I121	R:R:P211	6.77	No	No	0	7	8
68	R:R:I121	R:R:L212	5.71	No	No	0	7	7
69	R:R:F282	R:R:I121	7.54	Yes	No	0	9	7
70	R:R:E122	R:R:V126	4.28	No	No	0	5	7
71	R:R:E122	R:R:V157	14.26	No	No	0	5	7
72	R:R:T123	R:R:V157	4.76	No	No	0	8	7
73	R:R:L124	R:R:M215	5.65	No	No	0	8	8
74	R:R:C125	R:R:I214	3.27	No	No	0	7	6
75	R:R:V129	R:R:V218	6.41	No	No	0	6	6
76	R:R:D130	R:R:R131	8.34	Yes	Yes	1	8	9
77	R:R:D130	R:R:S143	10.31	Yes	No	1	8	4
78	R:R:D130	R:R:L145	4.07	Yes	No	1	8	7
79	R:R:A134	R:R:R131	5.53	No	Yes	0	8	9
80	R:R:R131	R:R:Y141	6.17	Yes	Yes	1	9	7
81	R:R:L272	R:R:R131	3.64	No	Yes	1	7	9
82	R:R:T136	R:R:Y132	9.99	No	Yes	0	7	8
83	R:R:R221	R:R:Y132	7.2	No	Yes	0	5	8
84	R:R:V222	R:R:Y132	3.79	No	Yes	0	8	8
85	R:R:I135	R:R:Y141	3.63	No	Yes	0	9	7
86	R:R:P138	R:R:S137	5.34	No	No	0	8	6
87	R:R:F139	R:R:K140	3.72	No	No	0	6	5
88	R:R:K140	R:R:Q142	8.14	No	No	0	5	4
89	R:R:F264	R:R:Y141	9.28	Yes	Yes	1	4	7
90	R:R:E268	R:R:Y141	11.22	No	Yes	0	7	7
91	R:R:L272	R:R:Y141	4.69	No	Yes	1	7	7
92	R:R:L145	R:R:S143	4.5	No	No	1	7	4
93	R:R:I153	R:R:L145	2.85	No	No	0	6	7
94	R:R:N148	R:R:T146	4.39	No	No	5	4	8
95	R:R:K149	R:R:T146	10.51	No	No	5	5	8
96	R:R:K147	R:R:R151	6.19	No	No	4	1	3
97	R:R:K149	R:R:N148	4.2	No	No	5	5	4
98	R:R:I159	R:R:L163	2.85	No	No	0	4	4
99	R:R:F290	R:R:S204	6.61	Yes	No	0	7	5
100	R:R:I205	R:R:Y209	8.46	No	No	0	4	5
101	R:R:F208	R:R:F290	36.44	No	Yes	0	8	7
102	R:R:V213	R:R:Y209	18.93	No	No	0	4	5
103	R:R:P211	R:R:V210	3.53	No	No	0	8	5
104	R:R:L212	R:R:V216	2.98	No	No	0	7	5
105	R:R:L212	R:R:T283	2.95	No	No	0	7	7
106	R:R:M215	R:R:V216	3.04	No	No	0	8	5
107	R:R:M215	R:R:M279	7.22	No	Yes	0	8	8
108	R:R:G276	R:R:Y219	5.79	No	No	6	6	9
109	R:R:M279	R:R:Y219	8.38	Yes	No	6	8	9
110	R:R:F223	R:R:K227	11.17	No	No	0	6	6
111	R:R:K227	R:R:Q224	8.14	No	No	0	6	3
112	R:R:E225	R:R:R228	5.82	No	No	0	5	4
113	R:R:A226	R:R:F264	4.16	No	Yes	0	8	4
114	R:R:K232	R:R:R228	3.71	No	No	0	4	4
115	R:R:F264	R:R:Q229	11.71	Yes	No	0	4	7
116	R:R:F264	R:R:L230	6.09	Yes	No	1	4	5
117	R:R:H269	R:R:L230	16.71	Yes	No	1	5	5
118	R:R:K235	R:R:Q231	9.49	No	No	0	5	5
119	R:R:D234	R:R:S236	7.36	No	No	0	4	4
120	R:R:E237	R:R:H241	12.31	Yes	No	0	3	3
121	R:R:F240	R:R:R239	6.41	No	No	0	4	4
122	R:R:F264	R:R:H269	5.66	Yes	Yes	1	4	5
123	R:R:H269	R:R:L266	3.86	Yes	No	0	5	5
124	R:R:K270	R:R:K273	7.18	No	No	0	7	7
125	R:R:K273	R:R:S329	4.59	No	No	0	7	8
126	R:R:S329	R:R:T274	6.4	No	No	7	8	8
127	R:R:P330	R:R:T274	6.99	No	No	7	5	8
128	R:R:I278	R:R:L275	2.85	Yes	No	0	8	8
129	R:R:G276	R:R:M279	3.49	No	Yes	6	6	8
130	R:R:I277	R:R:I325	8.83	No	No	0	7	8
131	R:R:I278	R:R:N322	5.66	Yes	No	3	8	9
132	R:R:I278	R:R:I325	2.94	Yes	No	3	8	8
133	R:R:I278	R:R:Y326	13.3	Yes	Yes	3	8	9
134	R:R:G280	R:R:M279	3.49	No	Yes	0	5	8
135	R:R:F321	R:R:T281	5.19	No	No	0	6	6
136	R:R:F282	R:R:W286	11.02	Yes	Yes	2	9	8
137	R:R:F282	R:R:N318	8.46	Yes	Yes	2	9	9
138	R:R:L284	R:R:T283	4.42	No	No	0	5	7
139	R:R:C285	R:R:N318	3.15	No	Yes	0	9	9
140	R:R:F290	R:R:W286	3.01	Yes	Yes	0	7	8
141	R:R:G315	R:R:W286	12.67	No	Yes	0	7	8
142	R:R:N318	R:R:W286	11.3	Yes	Yes	2	9	8
143	R:R:L287	R:R:P288	4.93	No	No	0	6	9
144	R:R:I291	R:R:L287	7.14	No	No	0	6	6
145	R:R:L311	R:R:P288	3.28	No	No	0	5	9
146	R:R:F289	R:R:F290	7.5	No	Yes	0	6	7
147	R:R:F289	R:R:N312	14.5	No	No	0	6	5
148	R:R:I314	R:R:L311	2.85	No	No	0	7	5
149	R:R:N312	R:R:Y316	3.49	No	Yes	0	5	6
150	R:R:F321	R:R:V317	9.18	No	No	0	6	5
151	R:R:N318	R:R:S319	4.47	Yes	Yes	2	9	9
152	R:R:N322	R:R:Y326	3.49	No	Yes	3	9	9
153	R:R:I325	R:R:Y326	8.46	No	Yes	3	8	9
154	R:R:F332	R:R:Y326	4.13	Yes	Yes	0	9	9
155	R:R:P330	R:R:S329	5.34	No	No	7	5	8
156	R:R:F332	R:R:P330	8.67	Yes	No	0	9	5
157	R:R:F332	R:R:F336	5.36	Yes	Yes	0	9	7
158	R:R:Q337	R:R:R343	3.5	No	No	0	4	6
159	R:R:Q337	R:R:S345	4.33	No	No	0	4	3
160	R:R:L342	R:R:S346	9.01	No	No	0	8	2
161	R:R:R343	R:R:R344	10.66	No	No	0	6	4
162	R:R:C285	R:R:F321	2.79	No	No	0	9	6
163	R:R:A150	R:R:F71	2.77	No	Yes	0	7	8
164	R:R:L80	R:R:L84	2.77	No	No	0	7	5
165	R:R:E225	R:R:I135	2.73	No	No	0	5	9
166	R:R:E338	R:R:I334	2.73	No	No	0	4	4
167	R:R:E237	R:R:K263	2.7	Yes	No	0	3	2
168	R:R:E268	R:R:K267	2.7	No	No	0	7	6
169	R:R:F336	R:R:V54	2.62	Yes	No	0	7	9
170	R:R:F133	R:R:V129	2.62	No	No	0	5	6
171	R:R:F217	R:R:V213	2.62	No	No	0	4	4
172	R:R:V222	R:R:Y219	2.52	No	No	0	8	9
173	R:R:F108	R:R:I112	2.51	No	No	0	5	4
174	R:R:F49	R:R:L45	2.44	No	No	0	4	5
175	R:R:F208	R:R:L287	2.44	No	No	0	8	6
176	R:R:L310	R:R:W313	2.28	No	No	0	5	5
177	R:R:F133	R:R:Y132	2.06	No	Yes	0	5	8
178	R:R:G320	R:R:P323	2.03	No	No	0	7	9
179	R:R:G320	R:R:I47	1.76	No	Yes	0	7	8
180	R:R:G37	R:R:M40	1.75	No	No	0	5	6
181	R:R:A78	R:R:S120	1.71	No	No	0	8	9
182	R:R:G162	R:R:L115	1.71	No	No	0	4	5
183	R:R:C125	R:R:V129	1.71	No	No	0	7	6
184	R:R:A85	R:R:V81	1.7	No	No	0	4	7
185	R:R:A119	R:R:V157	1.7	No	No	0	7	7
186	R:R:A128	R:R:V218	1.7	No	No	0	8	6
187	R:R:C116	R:R:I112	1.64	No	No	0	7	4
188	R:R:E237	R:R:G238	1.64	Yes	No	0	3	4
189	R:R:S203	R:R:S207	1.63	No	No	0	5	5
190	R:R:A46	R:R:I47	1.62	No	Yes	0	5	8
191	R:R:A59	R:R:I58	1.62	No	No	0	4	7
192	R:R:S203	R:R:V206	1.62	No	No	0	5	4
193	R:R:C265	R:R:K267	1.62	No	No	0	3	6
194	R:R:A57	R:R:L64	1.58	No	No	0	8	8
195	R:R:A57	R:R:L339	1.58	No	Yes	0	8	6
196	R:R:I38	R:R:S41	1.55	No	No	0	5	4
197	R:R:I153	R:R:V152	1.54	No	No	0	6	4
198	R:R:K149	R:R:V152	1.52	No	No	0	5	4
199	R:R:A271	R:R:E268	1.51	No	No	0	8	7
200	R:R:L144	R:R:S137	1.5	No	No	0	4	6
201	R:R:G238	R:R:R239	1.5	No	No	0	4	4
202	R:R:L80	R:R:V52	1.49	No	No	0	7	3
203	R:R:L311	R:R:V307	1.49	No	No	0	5	4
204	R:R:I43	R:R:I47	1.47	No	Yes	0	6	8
205	R:R:I159	R:R:M156	1.46	No	No	0	4	4
206	R:R:Q224	R:R:S220	1.44	No	No	0	3	3
207	R:R:I159	R:R:L155	1.43	No	No	0	4	3
208	R:R:C327	R:R:F336	1.4	No	Yes	0	7	7
209	R:R:D331	R:R:I334	1.4	No	No	0	7	4
210	R:R:E237	R:R:I233	1.37	Yes	No	0	3	6
211	R:R:F217	R:R:V216	1.31	No	No	0	4	5
212	R:R:H269	R:R:K227	1.31	Yes	No	0	5	6
213	R:R:D234	R:R:E237	1.3	No	Yes	0	4	3
214	R:R:R63	R:R:T66	1.29	No	No	0	6	7
215	R:R:K235	R:R:R239	1.24	No	No	0	5	4
216	R:R:I43	R:R:W313	1.17	No	No	0	6	5
217	R:R:L155	R:R:W158	1.14	No	No	0	3	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	R:R:I47	3.12833	6	2	8
2	R:R:L53	6.3375	4	0	6
3	R:R:F71	4.9	7	1	8
4	R:R:M82	6.3625	4	2	7
5	R:R:T118	5.57	4	0	6
6	R:R:D130	6.376	5	1	8
7	R:R:R131	6.03	5	1	9
8	R:R:Y132	5.76	4	0	8
9	R:R:Y141	6.998	5	1	7
10	R:R:E237	3.864	5	0	3
11	R:R:F264	7.38	5	1	4
12	R:R:H269	6.885	4	1	5
13	R:R:I278	6.1875	4	3	8
14	R:R:M279	5.645	4	6	8
15	R:R:F282	8.7375	4	2	9
16	R:R:W286	10.296	5	2	8
17	R:R:F290	13.39	4	0	7
18	R:R:Y316	5.065	4	2	6
19	R:R:N318	6.845	4	2	9
20	R:R:S319	6.0225	4	2	9
21	R:R:Y326	7.326	5	3	9
22	R:R:F332	6.05	4	0	9
23	R:R:F336	3.2575	4	0	7
24	R:R:L339	3.6925	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:I43	R:R:I47	10.8523	1.47	No	Yes	0	6	8
2	R:R:I47	R:R:S319	28.7909	6.19	Yes	Yes	2	8	9
3	R:R:A76	R:R:I55	23.8355	3.25	No	No	0	9	7
4	R:R:A76	R:R:V54	25.8548	3.39	No	No	0	9	9
5	R:R:F336	R:R:V54	27.8494	2.62	Yes	No	0	7	9
6	R:R:F332	R:R:F336	57.9658	5.36	Yes	Yes	0	9	7
7	R:R:F332	R:R:Y326	71.0109	4.13	Yes	Yes	0	9	9
8	R:R:I278	R:R:Y326	72.1135	13.3	Yes	Yes	3	8	9
9	R:R:I278	R:R:L275	78.5927	2.85	Yes	No	0	8	8
10	R:R:L275	R:R:T68	79.7696	2.95	No	No	0	8	8
11	R:R:R131	R:R:T68	80.9217	6.47	Yes	No	0	9	8
12	R:R:D130	R:R:R131	100	8.34	Yes	Yes	1	8	9
13	R:R:D130	R:R:F71	96.11	4.78	Yes	Yes	1	8	8
14	R:R:F71	R:R:I154	88.4911	6.28	Yes	No	0	8	8
15	R:R:I154	R:R:S74	88.5035	3.1	No	No	0	8	9
16	R:R:L75	R:R:S74	88.838	3	No	No	0	9	9
17	R:R:L124	R:R:L75	99.4054	4.15	No	No	0	8	9
18	R:R:L124	R:R:M215	99.0337	5.65	No	No	0	8	8
19	R:R:M215	R:R:V216	90.2998	3.04	No	No	0	8	5
20	R:R:L212	R:R:V216	86.1497	2.98	No	No	0	7	5
21	R:R:I121	R:R:L212	83.3622	5.71	No	No	0	7	7
22	R:R:F282	R:R:I121	80.3518	7.54	Yes	No	0	9	7
23	R:R:F282	R:R:N318	53.6422	8.46	Yes	Yes	2	9	9
24	R:R:N318	R:R:S319	50.607	4.47	Yes	Yes	2	9	9
25	R:R:F336	R:R:L53	31.7641	3.65	Yes	Yes	0	7	6
26	R:R:L339	R:R:L53	23.8355	4.15	Yes	Yes	0	6	6
27	R:R:I55	R:R:T73	13.3672	4.56	No	No	0	7	6
28	R:R:I58	R:R:T73	11.1992	6.08	No	No	0	7	6
29	R:R:F61	R:R:L339	13.169	6.09	No	Yes	0	6	6
30	R:R:F71	R:R:V126	15.4856	5.24	Yes	No	0	8	7
31	R:R:L75	R:R:T123	15.5476	4.42	No	No	0	9	8
32	R:R:T123	R:R:V157	14.6432	4.76	No	No	0	8	7
33	R:R:E122	R:R:V157	14.5813	14.26	No	No	0	5	7
34	R:R:E122	R:R:V126	14.5317	4.28	No	No	0	5	7
35	R:R:F71	R:R:I153	11.9301	6.28	Yes	No	0	8	6
36	R:R:S74	R:R:W158	12.9584	3.71	No	No	0	9	9
37	R:R:C116	R:R:M82	11.5089	4.86	No	Yes	0	7	7
38	R:R:M82	R:R:S319	20.7879	4.6	Yes	Yes	2	7	9
39	R:R:A119	R:R:V157	21.2958	1.7	No	No	0	7	7
40	R:R:A119	R:R:S161	19.2765	3.42	No	No	0	7	8
41	R:R:S161	R:R:T118	13.0699	4.8	No	Yes	0	8	6
42	R:R:F133	R:R:V129	10.9514	2.62	No	No	0	5	6
43	R:R:F133	R:R:Y132	13.0699	2.06	No	Yes	0	5	8
44	R:R:V222	R:R:Y132	19.2765	3.79	No	Yes	0	8	8
45	R:R:V222	R:R:Y219	21.2958	2.52	No	No	0	8	9
46	R:R:M279	R:R:Y219	23.1541	8.38	Yes	No	6	8	9
47	R:R:M215	R:R:M279	29.1254	7.22	No	Yes	0	8	8
48	R:R:R131	R:R:Y141	39.061	6.17	Yes	Yes	1	9	7
49	R:R:F264	R:R:Y141	21.7914	9.28	Yes	Yes	1	4	7
50	R:R:I153	R:R:V152	12.2275	1.54	No	No	0	6	4
51	R:R:F290	R:R:W286	22.1506	3.01	Yes	Yes	0	7	8
52	R:R:F208	R:R:F290	15.3617	36.44	No	Yes	0	8	7
53	R:R:F264	R:R:H269	13.2929	5.66	Yes	Yes	1	4	5
54	R:R:F332	R:R:P330	11.1992	8.67	Yes	No	0	9	5
55	R:R:F208	R:R:L287	13.3176	2.44	No	No	0	8	6
56	R:R:F282	R:R:W286	23.3276	11.02	Yes	Yes	2	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

there is no ligand in network 3KJ6

PDB Summary
PDB	3KJ6
Class	A
SubFamily	Amine
Type	Adrenergic
SubType	Beta2
Species	Homo sapiens
Ligand	-
Other Ligand(s)	-
Protein Partners	-
PDB Resolution	3.4
Date	2010-02-16
D.O.I.	10.1038/nature08650

Net Summary
I_min	2.85
Number of Linked Nodes	208
Number of Links	217
Number of Hubs	24
Number of Links mediated by Hubs	90
Number of Communities	7
Number of Nodes involved in Communities	37
Number of Links involved in Communities	44

Path Summary
Number Of Nodes in MetaPath	57
Number Of Links MetaPath	56
Number of Shortest Paths	16565
Length Of Smallest Path	3
Average Path Length	14.2636
Length of Longest Path	32
Minimum Path Strength	1.285
Average Path Strength	5.34868
Maximum Path Strength	21.97
Minimum Path Correlation	0.7
Average Path Correlation	0.928673
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	50.4091
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	37.6998
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier
SCOP2	Family Identifier
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P07550
Sequence	>3KJ6_Chain_R G M G I V M S L I V L A I V F G N V L V I T A I A F E R L Q T V T N Y F I T S L A C A D L V M G L A V V P F G A F W T S I D V L C V T A S I E T L C V I A V D R Y F A I T S P F K Y Q S L L T K N K A R V I I L M V W I V S G L T S S I V S F Y V P L V I M V F V Y S R V F Q E A K R Q L Q K I D K S E G R F H V K F C L K E H K A L K T L G I I M G T F T L C W L P F F I V Y I L L N W I G Y V N S G F N P L I Y C R S P D F R I A F Q E L L C L R R S S Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	2R4R	A	Amine	Adrenergic	β₂	Homo sapiens	-	-	-	3.4	2007-11-06	10.1038/nature06325
	2R4S	A	Amine	Adrenergic	β₂	Homo sapiens	-	-	-	3.4	2007-11-06	10.1038/nature06325
	2RH1	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	2.4	2007-10-30	10.1126/science.1150577
	3D4S	A	Amine	Adrenergic	β₂	Homo sapiens	Timolol Maleate	-	-	2.8	2008-06-17	10.1016/j.str.2008.05.001
	3NY8	A	Amine	Adrenergic	β₂	Homo sapiens	ICI 118-551	-	-	2.84	2010-08-11	10.1021/ja105108q
	3NY9	A	Amine	Adrenergic	β₂	Homo sapiens	PubChem 913103	-	-	2.84	2010-08-11	10.1021/ja105108q
	3NYA	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	-	-	3.16	2010-08-11	10.1021/ja105108q
	3P0G	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	-	3.5	2011-01-19	10.1038/nature09648
	3PDS	A	Amine	Adrenergic	β₂	Homo sapiens	Hydroxybenzylisoproterenol	-	-	3.5	2011-01-12	10.1038/nature09665
	3SN6	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	Gs/&β;1/&γ;2	3.2	2011-07-20	10.1038/nature10361
	4GBR	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.99	2012-10-24	10.1371/journal.pone.0046039
	4LDE	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	-	2.79	2013-09-25	10.1038/nature12572
	4LDL	A	Amine	Adrenergic	β₂	Homo sapiens	Hydroxybenzylisoproterenol	-	-	3.1	2013-09-25	10.1038/nature12572
	4LDO	A	Amine	Adrenergic	β₂	Homo sapiens	L-Epinephrine	-	-	3.2	2013-09-25	10.1038/nature12572
	4QKX	A	Amine	Adrenergic	β₂	Homo sapiens	PubChem 76210628	-	-	3.3	2014-07-23	10.1073/pnas.1410415111
	5D5A	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	2.48	2016-01-13	10.1107/S2059798315021683
	5D5B	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.8	2016-01-13	10.1107/S2059798315021683
	5D6L	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.2	2016-08-17	10.1038/nprot.2017.057
	5JQH	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.2	2016-07-13	10.1038/nature18636
	5X7D	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	PubChem 129318963	-	2.7	2017-08-16	10.1038/nature23652
	6E67	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	Gs (fused)	3.7	2019-06-05	10.1016/j.cell.2019.04.021
	6MXT	A	Amine	Adrenergic	β₂	Homo sapiens	Salmeterol	-	-	2.96	2018-11-14	10.1038/s41589-018-0145-x
	6N48	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	PubChem 138454256	-	3.2	2019-06-26	10.1126/science.aaw8981
	6NI3	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	Gs/&β;1/&γ;2	3.8	2019-11-20	10.1038/s41594-019-0330-y
	6OBA	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	GTPL11074	-	3.1	2020-03-25	10.1038/s41589-020-0549-2
	6PRZ	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	-	-	2.8	2019-11-13	10.1107/S2052252519013137
	6PS0	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carazolol	-	-	3.4	2019-11-13	10.1107/S2052252519013137
	6PS1	A	Amine	Adrenergic	β₂	Homo sapiens	Timolol	-	-	3.2	2019-11-13	10.1107/S2052252519013137
	6PS2	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Alprenolol	-	-	2.4	2019-11-13	10.1107/S2052252519013137
	6PS3	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Carvedilol	-	-	2.5	2019-11-13	10.1107/S2052252519013137
	6PS4	A	Amine	Adrenergic	β₂	Homo sapiens	ICI 118-551	-	-	2.6	2019-11-13	10.1107/S2052252519013137
	6PS5	A	Amine	Adrenergic	β₂	Homo sapiens	(S)-Propranolol	-	-	2.9	2019-11-13	10.1107/S2052252519013137
	6PS6	A	Amine	Adrenergic	β₂	Homo sapiens	Timolol	-	-	2.7	2019-11-13	10.1107/S2052252519013137
	7BZ2	A	Amine	Adrenergic	β₂	Homo sapiens	Arformoterol	-	Gs/&β;1/&γ;2	3.82	2020-08-05	10.1038/s41421-020-0176-9
	7DHI	A	Amine	Adrenergic	β₂	Homo sapiens	Salbutamol	-	Gs/&β;1/&γ;2	3.26	2020-12-16	10.1093/nsr/nwaa284
	7DHR	A	Amine	Adrenergic	β₂	Homo sapiens	Isoprenaline	-	Gs/&β;1/&γ;2	3.8	2020-12-16	10.1093/nsr/nwaa284
	7XKA	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.1	2023-04-26	10.1038/s41467-023-37808-y
	8GDZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GE1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GE3	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8GE4	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8GE6	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GE7	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GE8	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GE9	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GEA	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GEB	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8GEC	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GED	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GEE	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.7	2024-03-06	10.1038/s41586-024-07153-1
	8GEF	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.8	2024-03-06	10.1038/s41586-024-07153-1
	8GEG	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	3.8	2024-03-06	10.1038/s41586-024-07153-1
	8GEH	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	4	2024-03-06	10.1038/s41586-024-07153-1
	8GEI	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	4.1	2024-03-06	10.1038/s41586-024-07153-1
	8GEJ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	Gs/&β;1/&γ;2	4.2	2024-03-06	10.1038/s41586-024-07153-1
	8GFV	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.1	2024-03-06	10.1038/s41586-024-07153-1
	8GFW	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
	8GFX	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
	8GFY	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
	8GFZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
	8GG0	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	2.9	2024-03-06	10.1038/s41586-024-07153-1
	8GG1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
	8GG2	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3	2024-03-06	10.1038/s41586-024-07153-1
	8GG3	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.1	2024-03-06	10.1038/s41586-024-07153-1
	8GG4	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.2	2024-03-06	10.1038/s41586-024-07153-1
	8GG5	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.2	2024-03-06	10.1038/s41586-024-07153-1
	8GG6	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8GG7	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8GG8	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8GG9	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GGA	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGB	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGC	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GGE	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGF	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8GGI	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGJ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGK	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8GGL	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
	8GGM	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
	8GGN	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8GGO	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
	8GGP	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.2	2024-03-06	10.1038/s41586-024-07153-1
	8GGQ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GGR	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GGS	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGT	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGU	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8GGV	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8GGW	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8GGX	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8GGY	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.9	2024-03-06	10.1038/s41586-024-07153-1
	8GGZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	3.9	2024-03-06	10.1038/s41586-024-07153-1
	8GH0	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	4	2024-03-06	10.1038/s41586-024-07153-1
	8GH1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	-	-	4.1	2024-03-06	10.1038/s41586-024-07153-1
	8JJ8	A	Amine	Adrenergic	β₂	Homo sapiens	Formoterol	-	-	3.2	2023-09-06	10.1038/s41589-023-01389-0
	8JJL	A	Amine	Adrenergic	β₂	Homo sapiens	Olodaterol	-	-	3.2	2023-09-06	10.1038/s41589-023-01389-0
	8JJO	A	Amine	Adrenergic	β₂	Homo sapiens	Alprenolol	-	-	3.4	2023-09-06	10.1038/s41589-023-01389-0
	8UNL	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8UNM	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8UNN	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8UNO	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8UNP	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8UNQ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8UNR	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8UNS	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8UNT	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8UNU	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8UNV	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.3	2024-03-06	10.1038/s41586-024-07153-1
	8UNW	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.4	2024-03-06	10.1038/s41586-024-07153-1
	8UNX	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8UNY	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8UNZ	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.8	2024-03-06	10.1038/s41586-024-07153-1
	8UO0	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8UO1	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP; Mg	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8UO2	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP	Gs/&β;1/&γ;2	3.6	2024-03-06	10.1038/s41586-024-07153-1
	8UO3	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP; Mg	Gs/&β;1/&γ;2	3.5	2024-03-06	10.1038/s41586-024-07153-1
	8UO4	A	Amine	Adrenergic	β₂	Homo sapiens	Epinephrine	GTP; Mg	Gs/&β;1/&γ;2	4	2024-03-06	10.1038/s41586-024-07153-1

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