Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:I47 4.344538
2R:R:F71 5.664518
3R:R:V87 4.96437
4R:R:T118 5.57406
5R:R:I127 4.665419
6R:R:D130 7.805418
7R:R:R131 6.30286719
8R:R:Y132 8.04408
9R:R:Y141 6.3525417
10R:R:L145 3.6417
11R:R:S161 3.8975408
12R:R:Y219 5.66409
13R:R:L230 8.415415
14R:R:E237 3.865403
15R:R:F264 6.02614
16R:R:H269 10.7075415
17R:R:I278 5.3325428
18R:R:F282 7.5275409
19R:R:W286 10.0925408
20R:R:L287 3.8975406
21R:R:F290 11.5225407
22R:R:N318 6.638529
23R:R:N322 7.055429
24R:R:P323 3.66409
25R:R:I325 7.625408
26R:R:Y326 8.3629
27R:R:P330 8.3425
28R:R:F332 6.8025429
29R:R:F336 2.472507
30R:R:L339 2.75406
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:I47 R:R:V44 19.12626.14YesNo386
2R:R:V44 R:R:V48 16.97411.6NoNo066
3R:R:L84 R:R:V48 14.223313.41NoNo056
4R:R:F49 R:R:G50 13.91593.01NoNo048
5R:R:G50 R:R:P323 16.45634.06NoYes089
6R:R:N51 R:R:P323 42.44343.26NoYes099
7R:R:D79 R:R:N51 40.032412.12NoNo099
8R:R:D79 R:R:I47 34.90292.8NoYes398
9R:R:F49 R:R:L53 11.504917.05NoNo046
10R:R:L80 R:R:L84 11.44012.77NoNo075
11R:R:N322 R:R:P323 57.81553.26YesYes099
12R:R:I278 R:R:N322 84.04537.08YesYes289
13R:R:I278 R:R:L275 94.61162.85YesNo088
14R:R:L275 R:R:T68 94.22334.42NoNo088
15R:R:R131 R:R:T68 93.834910.35YesNo098
16R:R:I127 R:R:R131 1003.76YesYes199
17R:R:F71 R:R:I127 59.27188.79YesYes189
18R:R:F71 R:R:I154 56.50496.28YesNo088
19R:R:I154 R:R:Y70 14.22332.42NoNo084
20R:R:A57 R:R:L64 15.1781.58NoNo088
21R:R:A57 R:R:F336 17.62141.39NoYes087
22R:R:F332 R:R:F336 38.44663.22YesYes097
23R:R:F332 R:R:Y326 20.63119.28YesYes299
24R:R:N322 R:R:Y326 30.19426.98YesYes299
25R:R:F332 R:R:N69 32.02276.04YesNo099
26R:R:N69 R:R:T66 36.8775.85NoNo097
27R:R:Q142 R:R:T66 34.33662.83NoNo047
28R:R:Q142 R:R:R131 32.81555.84NoYes049
29R:R:D130 R:R:R131 11.77999.53YesYes189
30R:R:I127 R:R:T123 56.8773.04YesNo198
31R:R:L75 R:R:T123 52.00654.42NoNo198
32R:R:L124 R:R:L75 50.08092.77NoNo189
33R:R:N318 R:R:N322 89.514610.9YesYes299
34R:R:F282 R:R:N318 85.77678.46YesYes099
35R:R:F282 R:R:W286 69.708710.02YesYes098
36R:R:F290 R:R:W286 59.66027.02YesYes078
37R:R:F289 R:R:F290 32.08748.57NoYes067
38R:R:F289 R:R:N312 29.579312.08NoNo065
39R:R:N312 R:R:Y316 27.03886.98NoNo056
40R:R:M82 R:R:Y316 21.86082.39NoNo076
41R:R:M82 R:R:V86 16.68287.61NoNo077
42R:R:I112 R:R:V86 11.2466.14NoNo047
43R:R:I47 R:R:V87 10.85764.61YesYes387
44R:R:I154 R:R:W158 42.70232.35NoNo089
45R:R:A119 R:R:W158 40.27513.89NoNo079
46R:R:A119 R:R:S161 37.81553.42NoYes078
47R:R:S161 R:R:T118 16.97414.8YesYes086
48R:R:F282 R:R:I121 16.56965.02YesNo097
49R:R:E122 R:R:S161 14.19092.87NoYes058
50R:R:L124 R:R:M279 39.78964.24NoNo188
51R:R:M279 R:R:Y219 38.04219.58NoYes089
52R:R:V222 R:R:Y219 25.1782.52NoYes089
53R:R:V222 R:R:Y132 22.50815.05NoYes088
54R:R:F133 R:R:Y132 11.50493.09NoYes058
55R:R:R131 R:R:Y141 37.36258.23YesYes197
56R:R:F264 R:R:Y141 32.60524.13YesYes147
57R:R:F208 R:R:F290 27.168327.86NoYes087
58R:R:F208 R:R:L287 16.68283.65NoYes086
59R:R:P330 R:R:Y326 13.86736.95YesYes259
60R:R:P330 R:R:S329 11.39165.34YesNo258
61R:R:F336 R:R:Q337 16.10032.34YesNo074
62R:R:I278 R:R:Y326 13.70558.46YesYes289
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


PDB Summary
PDB 2R4S
Class A
SubFamily Amine
Type Adrenergic
SubType Beta2
Species Homo sapiens
Ligand -
Other Ligand(s) -
Protein Partners -
PDB Resolution 3.4
Date 2007-11-06
D.O.I. 10.1038/nature06325
Net Summary
Imin 2.77
Number of Linked Nodes 197
Number of Links 212
Number of Hubs 30
Number of Links mediated by Hubs 107
Number of Communities 4
Number of Nodes involved in Communities 41
Number of Links involved in Communities 56
Path Summary
Number Of Nodes in MetaPath 63
Number Of Links MetaPath 62
Number of Shortest Paths 15562
Length Of Smallest Path 3
Average Path Length 11.999
Length of Longest Path 30
Minimum Path Strength 1.22
Average Path Strength 6.09595
Maximum Path Strength 20.12
Minimum Path Correlation 0.7
Average Path Correlation 0.941307
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 5.26316
Average % Of Corr. Nodes 61.6741
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 47.0038
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier
SCOP2Family Identifier
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP07550
Sequence
>2R4S_Chain_R
GIVMSLIVL AIVFGNVLV ITAIAFERL QTVTNYFIT SLACADLVM 
GLAVVPFGF WTSIDVLCV TASIETLCV IAVDRYFAI TSPFKYQSL 
LTKNKARVI ILMVWIVSG LTSSIVSFY VPLVIMVFV YSRVFQEAK 
RQLQKIDKS EGRFHVFCL KEHKALKTL GIIMGTFTL CWLPFFILN 
WIGYVNSGF NPLIYCRSP DFRIAFQEL LCLRRSSLK


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
2R4RAAmineAdrenergicβ2Homo sapiens---3.42007-11-0610.1038/nature06325
2RH1AAmineAdrenergicβ2Homo sapiens(S)-Carazolol--2.42007-10-3010.1126/science.1150577
3D4SAAmineAdrenergicβ2Homo sapiensTimolol Maleate--2.82008-06-1710.1016/j.str.2008.05.001
3KJ6AAmineAdrenergicβ2Homo sapiens---3.42010-02-1610.1038/nature08650
3NY8AAmineAdrenergicβ2Homo sapiensICI 118-551--2.842010-08-1110.1021/ja105108q
3NY9AAmineAdrenergicβ2Homo sapiensPubChem 913103--2.842010-08-1110.1021/ja105108q
3NYAAAmineAdrenergicβ2Homo sapiens(S)-Alprenolol--3.162010-08-1110.1021/ja105108q
3P0GAAmineAdrenergicβ2Homo sapiensBI167107--3.52011-01-1910.1038/nature09648
3PDSAAmineAdrenergicβ2Homo sapiensHydroxybenzylisoproterenol--3.52011-01-1210.1038/nature09665
3SN6AAmineAdrenergicβ2Homo sapiensBI167107-Gs/&β;1/&γ;23.22011-07-2010.1038/nature10361
4GBRAAmineAdrenergicβ2Homo sapiens(S)-Carazolol--3.992012-10-2410.1371/journal.pone.0046039
4LDEAAmineAdrenergicβ2Homo sapiensBI167107--2.792013-09-2510.1038/nature12572
4LDLAAmineAdrenergicβ2Homo sapiensHydroxybenzylisoproterenol--3.12013-09-2510.1038/nature12572
4LDOAAmineAdrenergicβ2Homo sapiensL-Epinephrine--3.22013-09-2510.1038/nature12572
4QKXAAmineAdrenergicβ2Homo sapiensPubChem 76210628--3.32014-07-2310.1073/pnas.1410415111
5D5AAAmineAdrenergicβ2Homo sapiens(S)-Carazolol--2.482016-01-1310.1107/S2059798315021683
5D5BAAmineAdrenergicβ2Homo sapiens(S)-Carazolol--3.82016-01-1310.1107/S2059798315021683
5D6LAAmineAdrenergicβ2Homo sapiens(S)-Carazolol--3.22016-08-1710.1038/nprot.2017.057
5JQHAAmineAdrenergicβ2Homo sapiens(S)-Carazolol--3.22016-07-1310.1038/nature18636
5X7DAAmineAdrenergicβ2Homo sapiens(S)-CarazololPubChem 129318963-2.72017-08-1610.1038/nature23652
6E67AAmineAdrenergicβ2Homo sapiensBI167107-Gs (fused)3.72019-06-0510.1016/j.cell.2019.04.021
6MXTAAmineAdrenergicβ2Homo sapiensSalmeterol--2.962018-11-1410.1038/s41589-018-0145-x
6N48AAmineAdrenergicβ2Homo sapiensBI167107PubChem 138454256-3.22019-06-2610.1126/science.aaw8981
6NI3AAmineAdrenergicβ2Homo sapiensBI167107-Gs/&β;1/&γ;23.82019-11-2010.1038/s41594-019-0330-y
6OBAAAmineAdrenergicβ2Homo sapiens(S)-AlprenololGTPL11074-3.12020-03-2510.1038/s41589-020-0549-2
6PRZAAmineAdrenergicβ2Homo sapiens(S)-Alprenolol--2.82019-11-1310.1107/S2052252519013137
6PS0AAmineAdrenergicβ2Homo sapiens(S)-Carazolol--3.42019-11-1310.1107/S2052252519013137
6PS1AAmineAdrenergicβ2Homo sapiensTimolol--3.22019-11-1310.1107/S2052252519013137
6PS2AAmineAdrenergicβ2Homo sapiens(S)-Alprenolol--2.42019-11-1310.1107/S2052252519013137
6PS3AAmineAdrenergicβ2Homo sapiens(S)-Carvedilol--2.52019-11-1310.1107/S2052252519013137
6PS4AAmineAdrenergicβ2Homo sapiensICI 118-551--2.62019-11-1310.1107/S2052252519013137
6PS5AAmineAdrenergicβ2Homo sapiens(S)-Propranolol--2.92019-11-1310.1107/S2052252519013137
6PS6AAmineAdrenergicβ2Homo sapiensTimolol--2.72019-11-1310.1107/S2052252519013137
7BZ2AAmineAdrenergicβ2Homo sapiensArformoterol-Gs/&β;1/&γ;23.822020-08-0510.1038/s41421-020-0176-9
7DHIAAmineAdrenergicβ2Homo sapiensSalbutamol-Gs/&β;1/&γ;23.262020-12-1610.1093/nsr/nwaa284
7DHRAAmineAdrenergicβ2Homo sapiensIsoprenaline-Gs/&β;1/&γ;23.82020-12-1610.1093/nsr/nwaa284
7XKAAAmineAdrenergicβ2Homo sapiensEpinephrine--3.12023-04-2610.1038/s41467-023-37808-y
8GDZAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GE1AAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8GE3AAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8GE4AAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8GE6AAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8GE7AAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8GE8AAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8GE9AAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GEAAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GEBAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.62024-03-0610.1038/s41586-024-07153-1
8GECAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GEDAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GEEAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.72024-03-0610.1038/s41586-024-07153-1
8GEFAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.82024-03-0610.1038/s41586-024-07153-1
8GEGAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;23.82024-03-0610.1038/s41586-024-07153-1
8GEHAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;242024-03-0610.1038/s41586-024-07153-1
8GEIAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;24.12024-03-0610.1038/s41586-024-07153-1
8GEJAAmineAdrenergicβ2Homo sapiensEpinephrine-Gs/&β;1/&γ;24.22024-03-0610.1038/s41586-024-07153-1
8GFVAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.12024-03-0610.1038/s41586-024-07153-1
8GFWAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;232024-03-0610.1038/s41586-024-07153-1
8GFXAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;232024-03-0610.1038/s41586-024-07153-1
8GFYAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;232024-03-0610.1038/s41586-024-07153-1
8GFZAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;232024-03-0610.1038/s41586-024-07153-1
8GG0AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;22.92024-03-0610.1038/s41586-024-07153-1
8GG1AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;232024-03-0610.1038/s41586-024-07153-1
8GG2AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;232024-03-0610.1038/s41586-024-07153-1
8GG3AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.12024-03-0610.1038/s41586-024-07153-1
8GG4AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.22024-03-0610.1038/s41586-024-07153-1
8GG5AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.22024-03-0610.1038/s41586-024-07153-1
8GG6AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8GG7AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8GG8AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8GG9AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8GGAAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GGBAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GGCAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8GGEAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8GGFAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.62024-03-0610.1038/s41586-024-07153-1
8GGIAAmineAdrenergicβ2Homo sapiensEpinephrine--3.52024-03-0610.1038/s41586-024-07153-1
8GGJAAmineAdrenergicβ2Homo sapiensEpinephrine--3.52024-03-0610.1038/s41586-024-07153-1
8GGKAAmineAdrenergicβ2Homo sapiensEpinephrine--3.32024-03-0610.1038/s41586-024-07153-1
8GGLAAmineAdrenergicβ2Homo sapiensEpinephrine--3.22024-03-0610.1038/s41586-024-07153-1
8GGMAAmineAdrenergicβ2Homo sapiensEpinephrine--3.22024-03-0610.1038/s41586-024-07153-1
8GGNAAmineAdrenergicβ2Homo sapiensEpinephrine--3.32024-03-0610.1038/s41586-024-07153-1
8GGOAAmineAdrenergicβ2Homo sapiensEpinephrine--3.22024-03-0610.1038/s41586-024-07153-1
8GGPAAmineAdrenergicβ2Homo sapiensEpinephrine--3.22024-03-0610.1038/s41586-024-07153-1
8GGQAAmineAdrenergicβ2Homo sapiensEpinephrine--3.42024-03-0610.1038/s41586-024-07153-1
8GGRAAmineAdrenergicβ2Homo sapiensEpinephrine--3.42024-03-0610.1038/s41586-024-07153-1
8GGSAAmineAdrenergicβ2Homo sapiensEpinephrine--3.52024-03-0610.1038/s41586-024-07153-1
8GGTAAmineAdrenergicβ2Homo sapiensEpinephrine--3.52024-03-0610.1038/s41586-024-07153-1
8GGUAAmineAdrenergicβ2Homo sapiensEpinephrine--3.42024-03-0610.1038/s41586-024-07153-1
8GGVAAmineAdrenergicβ2Homo sapiensEpinephrine--3.52024-03-0610.1038/s41586-024-07153-1
8GGWAAmineAdrenergicβ2Homo sapiensEpinephrine--3.62024-03-0610.1038/s41586-024-07153-1
8GGXAAmineAdrenergicβ2Homo sapiensEpinephrine--3.62024-03-0610.1038/s41586-024-07153-1
8GGYAAmineAdrenergicβ2Homo sapiensEpinephrine--3.92024-03-0610.1038/s41586-024-07153-1
8GGZAAmineAdrenergicβ2Homo sapiensEpinephrine--3.92024-03-0610.1038/s41586-024-07153-1
8GH0AAmineAdrenergicβ2Homo sapiensEpinephrine--42024-03-0610.1038/s41586-024-07153-1
8GH1AAmineAdrenergicβ2Homo sapiensEpinephrine--4.12024-03-0610.1038/s41586-024-07153-1
8JJ8AAmineAdrenergicβ2Homo sapiensFormoterol--3.22023-09-0610.1038/s41589-023-01389-0
8JJLAAmineAdrenergicβ2Homo sapiensOlodaterol--3.22023-09-0610.1038/s41589-023-01389-0
8JJOAAmineAdrenergicβ2Homo sapiensAlprenolol--3.42023-09-0610.1038/s41589-023-01389-0
8UNLAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8UNMAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8UNNAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8UNOAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8UNPAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8UNQAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8UNRAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8UNSAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8UNTAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8UNUAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8UNVAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.32024-03-0610.1038/s41586-024-07153-1
8UNWAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.42024-03-0610.1038/s41586-024-07153-1
8UNXAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.62024-03-0610.1038/s41586-024-07153-1
8UNYAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.62024-03-0610.1038/s41586-024-07153-1
8UNZAAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.82024-03-0610.1038/s41586-024-07153-1
8UO0AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8UO1AAmineAdrenergicβ2Homo sapiensEpinephrineGTP; MgGs/&β;1/&γ;23.62024-03-0610.1038/s41586-024-07153-1
8UO2AAmineAdrenergicβ2Homo sapiensEpinephrineGTPGs/&β;1/&γ;23.62024-03-0610.1038/s41586-024-07153-1
8UO3AAmineAdrenergicβ2Homo sapiensEpinephrineGTP; MgGs/&β;1/&γ;23.52024-03-0610.1038/s41586-024-07153-1
8UO4AAmineAdrenergicβ2Homo sapiensEpinephrineGTP; MgGs/&β;1/&γ;242024-03-0610.1038/s41586-024-07153-1




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 2R4S.zip



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You can also  read or  download a guide explaining the meaning of all files and numerical data.