psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D107	10.22	Yes	No	1	0	9
2	L:L:?1	R:R:Y108	22.07	Yes	Yes	1	0	9
3	L:L:?1	R:R:S111	12.72	Yes	No	0	0	9
4	L:L:?1	R:R:T112	5.55	Yes	Yes	1	0	9
5	L:L:?1	R:R:W158	7.5	Yes	Yes	1	0	8
6	L:L:?1	R:R:N198	6.46	Yes	Yes	1	0	9
7	L:L:?1	R:R:Y431	18.76	Yes	Yes	0	0	9
8	R:R:L30	R:R:L34	8.3	No	No	0	9	8
9	R:R:L89	R:R:V31	7.45	No	No	0	6	7
10	R:R:L34	R:R:W455	17.08	No	Yes	0	8	9
11	R:R:C38	R:R:M81	4.86	No	Yes	0	9	9
12	R:R:G77	R:R:T41	3.64	No	Yes	1	9	9
13	R:R:M81	R:R:T41	9.03	Yes	Yes	1	9	9
14	R:R:T41	R:R:T462	9.42	Yes	No	1	9	9
15	R:R:L44	R:R:P465	4.93	No	No	0	9	9
16	R:R:D73	R:R:N45	6.73	Yes	Yes	0	9	9
17	R:R:N45	R:R:P465	6.52	Yes	No	0	9	9
18	R:R:L46	R:R:L74	5.54	No	No	3	8	8
19	R:R:F479	R:R:L47	4.87	Yes	No	0	9	9
20	R:R:L47	R:R:L483	4.15	No	No	0	9	8
21	R:R:S70	R:R:V48	4.85	No	No	0	9	9
22	R:R:P469	R:R:V48	7.07	No	No	0	9	9
23	R:R:F479	R:R:V48	5.24	Yes	No	0	9	9
24	R:R:L49	R:R:S70	7.51	No	No	0	8	9
25	R:R:S54	R:R:Y50	5.09	No	No	0	7	5
26	R:R:V52	R:R:V67	4.81	No	No	0	8	8
27	R:R:E55	R:R:K57	9.45	Yes	No	0	8	7
28	R:R:E55	R:R:L58	5.3	Yes	Yes	4	8	9
29	R:R:E55	R:R:T478	7.06	Yes	No	4	8	8
30	R:R:E55	R:R:R481	6.98	Yes	No	0	8	6
31	R:R:F475	R:R:L58	14.61	Yes	Yes	0	9	9
32	R:R:L58	R:R:T478	7.37	Yes	No	4	9	8
33	R:R:N63	R:R:T60	8.77	No	No	0	9	9
34	R:R:K141	R:R:V61	4.55	No	No	0	8	9
35	R:R:F475	R:R:N63	8.46	Yes	No	0	9	9
36	R:R:I120	R:R:Y65	7.25	No	Yes	2	8	8
37	R:R:L121	R:R:Y65	5.86	No	Yes	2	9	8
38	R:R:D124	R:R:Y65	14.94	No	Yes	2	9	8
39	R:R:A144	R:R:Y65	4	No	Yes	0	9	8
40	R:R:T147	R:R:Y65	6.24	No	Yes	2	8	8
41	R:R:I148	R:R:Y65	3.63	No	Yes	0	9	8
42	R:R:I66	R:R:P469	5.08	No	No	0	9	9
43	R:R:S117	R:R:S68	4.89	No	No	0	8	9
44	R:R:I148	R:R:S68	6.19	No	No	0	9	9
45	R:R:S68	R:R:W152	6.18	No	Yes	0	9	9
46	R:R:L69	R:R:N464	15.1	No	No	0	9	9
47	R:R:V71	R:R:W152	3.68	No	Yes	0	6	9
48	R:R:D73	R:R:S114	5.89	Yes	No	0	9	9
49	R:R:D73	R:R:S461	10.31	Yes	No	0	9	9
50	R:R:D73	R:R:N464	10.77	Yes	No	0	9	9
51	R:R:V76	R:R:V80	4.81	No	Yes	1	9	9
52	R:R:V76	R:R:Y458	3.79	No	Yes	1	9	9
53	R:R:S461	R:R:V76	8.08	No	No	0	9	9
54	R:R:G77	R:R:M81	6.99	No	Yes	1	9	9
55	R:R:V80	R:R:W103	4.9	Yes	Yes	1	9	9
56	R:R:D107	R:R:V80	7.3	No	Yes	1	9	9
57	R:R:V80	R:R:Y458	5.05	Yes	Yes	1	9	9
58	R:R:M81	R:R:Y458	4.79	Yes	Yes	1	9	9
59	R:R:M83	R:R:W103	8.14	No	Yes	0	8	9
60	R:R:N84	R:R:W103	7.91	Yes	Yes	1	8	9
61	R:R:M451	R:R:N84	4.21	No	Yes	0	6	8
62	R:R:I454	R:R:N84	4.25	No	Yes	0	8	8
63	R:R:N84	R:R:W455	9.04	Yes	Yes	1	8	9
64	R:R:N84	R:R:Y458	8.14	Yes	Yes	1	8	9
65	R:R:L86	R:R:L95	4.15	No	No	0	6	9
66	R:R:W93	R:R:Y87	4.82	Yes	No	0	9	7
67	R:R:K179	R:R:Y87	7.17	No	No	0	4	7
68	R:R:M451	R:R:Y87	4.79	No	No	0	6	7
69	R:R:L88	R:R:M451	5.65	No	No	0	8	6
70	R:R:D178	R:R:K92	5.53	No	No	0	3	2
71	R:R:L95	R:R:W93	14.81	No	Yes	0	9	9
72	R:R:C100	R:R:W93	7.84	No	Yes	1	9	9
73	R:R:W103	R:R:W93	6.56	Yes	Yes	1	9	9
74	R:R:C180	R:R:W93	9.14	Yes	Yes	1	9	9
75	R:R:L95	R:R:L99	8.3	No	No	0	9	7
76	R:R:L101	R:R:R97	12.15	No	Yes	0	8	5
77	R:R:R175	R:R:R97	8.53	No	Yes	0	4	5
78	R:R:C100	R:R:C180	7.28	No	Yes	1	9	9
79	R:R:L101	R:R:L163	5.54	No	No	0	8	7
80	R:R:F102	R:R:M106	9.95	No	No	0	8	8
81	R:R:C180	R:R:W103	5.22	Yes	Yes	1	9	9
82	R:R:C180	R:R:L104	4.76	Yes	No	0	9	9
83	R:R:L104	R:R:T182	7.37	No	No	0	9	9
84	R:R:S105	R:R:V159	4.85	No	No	0	9	5
85	R:R:I162	R:R:S105	4.64	No	No	0	9	9
86	R:R:D107	R:R:Y458	11.49	No	Yes	1	9	9
87	R:R:W158	R:R:Y108	14.47	Yes	Yes	1	8	9
88	R:R:I162	R:R:Y108	4.84	No	Yes	0	9	9
89	R:R:T182	R:R:Y108	6.24	No	Yes	0	9	9
90	R:R:F156	R:R:V109	6.55	No	No	0	5	9
91	R:R:S111	R:R:W428	3.71	No	Yes	0	9	9
92	R:R:F116	R:R:T112	6.49	No	Yes	0	8	9
93	R:R:S155	R:R:T112	6.4	No	Yes	0	9	9
94	R:R:T112	R:R:W158	9.7	Yes	Yes	1	9	8
95	R:R:N198	R:R:T112	13.16	Yes	Yes	1	9	9
96	R:R:A113	R:R:W152	7.78	No	Yes	0	9	9
97	R:R:I115	R:R:N198	5.66	No	Yes	0	9	9
98	R:R:F424	R:R:I115	5.02	Yes	No	0	9	9
99	R:R:I115	R:R:W428	5.87	No	Yes	0	9	9
100	R:R:F424	R:R:V118	6.55	Yes	No	0	9	9
101	R:R:V118	R:R:Y468	6.31	No	Yes	0	9	9
102	R:R:F119	R:R:I123	6.28	Yes	No	0	8	6
103	R:R:F119	R:R:P202	5.78	Yes	No	0	8	9
104	R:R:F119	R:R:L205	7.31	Yes	No	0	8	6
105	R:R:F119	R:R:M206	3.73	Yes	Yes	0	8	9
106	R:R:I120	R:R:T147	4.56	No	No	2	8	8
107	R:R:L121	R:R:R125	3.64	No	No	2	9	9
108	R:R:L121	R:R:Y468	5.86	No	Yes	2	9	9
109	R:R:C122	R:R:M206	4.86	No	Yes	0	8	9
110	R:R:C122	R:R:Y210	13.44	No	Yes	0	8	9
111	R:R:F209	R:R:I123	3.77	Yes	No	0	7	6
112	R:R:D124	R:R:Y135	6.9	No	No	2	9	9
113	R:R:D124	R:R:R139	11.91	No	Yes	2	9	9
114	R:R:R125	R:R:Y468	4.12	No	Yes	2	9	9
115	R:R:Q130	R:R:Y126	12.4	No	Yes	0	8	9
116	R:R:F209	R:R:Y126	15.47	Yes	Yes	0	7	9
117	R:R:K212	R:R:Y126	4.78	No	Yes	0	5	9
118	R:R:I213	R:R:Y126	3.63	No	Yes	0	9	9
119	R:R:R127	R:R:Y135	20.58	No	No	0	8	9
120	R:R:R139	R:R:S128	7.91	Yes	No	0	9	9
121	R:R:Q131	R:R:R134	15.19	No	No	0	7	5
122	R:R:R139	R:R:Y135	10.29	Yes	No	2	9	9
123	R:R:K137	R:R:Y138	20.3	No	No	0	5	8
124	R:R:R143	R:R:Y138	4.12	No	No	0	9	8
125	R:R:F184	R:R:W158	4.01	Yes	Yes	1	9	8
126	R:R:T194	R:R:W158	7.28	No	Yes	0	8	8
127	R:R:N198	R:R:W158	5.65	Yes	Yes	1	9	8
128	R:R:F190	R:R:P161	5.78	Yes	No	0	9	9
129	R:R:M169	R:R:W165	10.47	No	Yes	0	5	9
130	R:R:D183	R:R:W165	4.47	No	Yes	0	7	9
131	R:R:F184	R:R:W165	9.02	Yes	Yes	1	9	9
132	R:R:V187	R:R:W165	7.36	No	Yes	0	8	9
133	R:R:F190	R:R:W165	10.02	Yes	Yes	1	9	9
134	R:R:D183	R:R:N166	5.39	No	No	0	7	6
135	R:R:V174	R:R:Y185	3.79	No	Yes	0	2	7
136	R:R:K179	R:R:R176	7.43	No	No	0	4	1
137	R:R:E181	R:R:Y185	14.59	No	Yes	0	7	7
138	R:R:E181	R:R:E447	5.07	No	No	0	7	4
139	R:R:F184	R:R:T182	11.67	Yes	No	0	9	9
140	R:R:F184	R:R:F190	8.57	Yes	Yes	1	9	9
141	R:R:D186	R:R:Y185	6.9	No	Yes	0	3	7
142	R:R:I438	R:R:Y185	3.63	No	Yes	0	6	7
143	R:R:V187	R:R:W189	6.13	No	No	0	8	5
144	R:R:F190	R:R:W189	8.02	Yes	No	0	9	5
145	R:R:F190	R:R:T194	10.38	Yes	No	0	9	8
146	R:R:F435	R:R:K191	16.13	No	No	0	8	9
147	R:R:I438	R:R:K191	4.36	No	No	0	6	9
148	R:R:M436	R:R:V192	7.61	No	No	0	7	8
149	R:R:F432	R:R:N198	7.25	Yes	Yes	0	9	9
150	R:R:F199	R:R:Y200	6.19	Yes	No	0	9	8
151	R:R:F199	R:R:T203	10.38	Yes	No	5	9	9
152	R:R:F199	R:R:F424	5.36	Yes	Yes	5	9	9
153	R:R:F199	R:R:F432	19.29	Yes	Yes	0	9	9
154	R:R:M436	R:R:Y200	4.79	No	No	0	7	8
155	R:R:F424	R:R:T203	3.89	Yes	No	5	9	9
156	R:R:F209	R:R:L205	3.65	Yes	No	0	7	6
157	R:R:M206	R:R:M421	5.78	Yes	No	0	9	9
158	R:R:F424	R:R:M206	3.73	Yes	Yes	0	9	9
159	R:R:L207	R:R:M421	5.65	No	No	0	7	9
160	R:R:F209	R:R:W208	4.01	Yes	No	0	7	4
161	R:R:K212	R:R:W208	4.64	No	No	0	5	4
162	R:R:I213	R:R:Y210	4.84	No	Yes	0	9	9
163	R:R:L417	R:R:Y210	4.69	No	Yes	0	9	9
164	R:R:I420	R:R:Y210	4.84	No	Yes	0	9	9
165	R:R:Q222	R:R:R218	9.35	No	Yes	0	7	7
166	R:R:E410	R:R:R218	4.65	No	Yes	0	8	7
167	R:R:H220	R:R:R224	9.03	No	No	0	8	8
168	R:R:C221	R:R:E410	4.56	No	No	0	5	8
169	R:R:E225	R:R:R409	15.12	No	No	0	4	8
170	R:R:E410	R:R:N408	3.94	No	No	0	8	7
171	R:R:I420	R:R:Q416	4.12	No	No	0	9	9
172	R:R:C471	R:R:Q416	9.16	No	No	0	9	9
173	R:R:F419	R:R:I467	6.28	No	No	0	7	9
174	R:R:I420	R:R:Y468	6.04	No	Yes	0	9	9
175	R:R:I425	R:R:M421	5.83	No	No	0	8	9
176	R:R:C427	R:R:N460	4.72	No	No	0	9	9
177	R:R:F432	R:R:W428	6.01	Yes	Yes	0	9	9
178	R:R:G457	R:R:W428	8.44	No	Yes	0	9	9
179	R:R:N460	R:R:W428	13.56	No	Yes	0	9	9
180	R:R:I429	R:R:I433	5.89	No	No	0	8	7
181	R:R:F432	R:R:Y431	11.35	Yes	Yes	0	9	9
182	R:R:F435	R:R:Y431	9.28	No	Yes	0	8	9
183	R:R:T453	R:R:Y431	4.99	No	Yes	0	9	9
184	R:R:C445	R:R:F434	4.19	No	No	0	5	7
185	R:R:F434	R:R:H450	11.31	No	No	0	7	7
186	R:R:C445	R:R:I438	8.18	No	No	0	5	6
187	R:R:C441	R:R:C444	7.28	No	No	6	7	5
188	R:R:H448	R:R:N446	12.75	No	No	0	2	6
189	R:R:H450	R:R:I454	3.98	No	No	0	7	8
190	R:R:F452	R:R:L456	7.31	No	No	0	5	9
191	R:R:W455	R:R:Y458	5.79	Yes	Yes	1	9	9
192	R:R:N460	R:R:N464	9.54	No	No	0	9	9
193	R:R:I467	R:R:Y468	7.25	No	Yes	0	9	9
194	R:R:F475	R:R:P469	7.22	Yes	No	0	9	9
195	R:R:E473	R:R:N472	3.94	No	No	0	5	9
196	R:R:F475	R:R:N472	8.46	Yes	No	0	9	9
197	R:R:F475	R:R:F479	9.65	Yes	Yes	0	9	9
198	R:R:D183	R:R:R97	3.57	No	Yes	0	7	5
199	R:R:I85	R:R:W455	3.52	No	Yes	0	8	9
200	R:R:L417	R:R:Y214	3.52	No	No	0	9	8
201	R:R:I160	R:R:P161	3.39	No	No	0	8	9
202	R:R:A413	R:R:V217	3.39	No	No	0	9	9
203	R:R:I429	R:R:P430	3.39	No	No	0	8	9
204	R:R:A439	R:R:T188	3.36	No	No	0	8	8
205	R:R:L201	R:R:P202	3.28	No	No	0	7	9
206	R:R:A110	R:R:I75	3.25	No	No	0	8	8
207	R:R:A151	R:R:I120	3.25	No	No	0	7	8
208	R:R:A195	R:R:M436	3.22	No	No	0	9	7
209	R:R:M90	R:R:S94	3.07	No	No	0	5	5
210	R:R:M106	R:R:V79	3.04	No	No	0	8	6
211	R:R:L44	R:R:V40	2.98	No	No	0	9	4
212	R:R:L46	R:R:V42	2.98	No	No	3	8	6
213	R:R:L74	R:R:V42	2.98	No	No	3	8	6
214	R:R:N45	R:R:S70	2.98	Yes	No	0	9	9
215	R:R:L49	R:R:V67	2.98	No	No	0	8	8
216	R:R:L49	R:R:V71	2.98	No	No	0	8	6
217	R:R:I425	R:R:I429	2.94	No	No	0	8	8
218	R:R:P98	R:R:R97	2.88	No	Yes	0	5	5
219	R:R:I482	R:R:L47	2.85	No	No	0	8	9
220	R:R:I459	R:R:L463	2.85	No	No	0	6	8
221	R:R:K141	R:R:L64	2.82	No	No	0	8	8
222	R:R:G96	R:R:W93	2.81	No	Yes	0	8	9
223	R:R:L44	R:R:L466	2.77	No	No	0	9	7
224	R:R:A51	R:R:F479	2.77	No	Yes	0	9	9
225	R:R:L86	R:R:L89	2.77	No	No	0	6	6
226	R:R:A423	R:R:F419	2.77	No	No	0	8	7
227	R:R:L74	R:R:N45	2.75	No	Yes	0	8	9
228	R:R:A414	R:R:Y214	2.67	No	No	0	9	8
229	R:R:R139	R:R:V61	2.62	Yes	No	0	9	9
230	R:R:F440	R:R:V192	2.62	No	No	0	7	8
231	R:R:A72	R:R:W152	2.59	No	Yes	0	9	9
232	R:R:F440	R:R:T188	2.59	No	No	0	7	8
233	R:R:F102	R:R:M83	2.49	No	No	0	8	8
234	R:R:F190	R:R:M193	2.49	Yes	No	0	9	7
235	R:R:K215	R:R:R218	2.48	No	Yes	0	6	7
236	R:R:K412	R:R:R411	2.48	No	No	0	9	7
237	R:R:F116	R:R:L154	2.44	No	No	0	8	7
238	R:R:F153	R:R:L154	2.44	No	No	0	5	7
239	R:R:F434	R:R:L449	2.44	No	No	0	7	4
240	R:R:I482	R:R:Y50	2.42	No	No	0	8	5
241	R:R:I75	R:R:W152	2.35	No	Yes	0	8	9
242	R:R:R409	R:R:R411	2.13	No	No	0	8	7
243	R:R:R127	R:R:Y138	2.06	No	No	0	8	8
244	R:R:R218	R:R:Y214	2.06	Yes	No	0	7	8
245	R:R:C38	R:R:P82	1.88	No	No	0	9	9
246	R:R:G43	R:R:V42	1.84	No	No	0	6	6
247	R:R:G62	R:R:T60	1.82	No	No	0	8	9
248	R:R:G164	R:R:L163	1.71	No	No	0	7	7
249	R:R:C221	R:R:V217	1.71	No	No	0	5	9
250	R:R:C441	R:R:V437	1.71	No	No	6	7	8
251	R:R:C444	R:R:V437	1.71	No	No	6	5	8
252	R:R:A78	R:R:V79	1.7	No	No	0	7	6
253	R:R:A216	R:R:V129	1.7	No	No	0	6	9
254	R:R:M28	R:R:P29	1.68	No	No	0	5	3
255	R:R:C427	R:R:I459	1.64	No	No	0	9	6
256	R:R:L456	R:R:P430	1.64	No	No	0	9	9
257	R:R:S35	R:R:V31	1.62	No	No	0	7	7
258	R:R:S155	R:R:V109	1.62	No	No	0	9	9
259	R:R:S128	R:R:V129	1.62	No	No	0	9	9
260	R:R:G164	R:R:H167	1.59	No	No	0	7	4
261	R:R:P132	R:R:Q131	1.58	No	No	0	9	7
262	R:R:T140	R:R:T142	1.57	No	No	0	9	6
263	R:R:I196	R:R:V192	1.54	No	No	0	7	8
264	R:R:I433	R:R:V437	1.54	No	No	0	7	8
265	R:R:I37	R:R:T36	1.52	No	No	0	7	5
266	R:R:I37	R:R:T41	1.52	No	Yes	1	7	9
267	R:R:I37	R:R:T462	1.52	No	No	1	7	9
268	R:R:F153	R:R:G150	1.51	No	No	0	5	5
269	R:R:L64	R:R:S145	1.5	No	No	0	8	6
270	R:R:I197	R:R:M193	1.46	No	No	0	5	7
271	R:R:K476	R:R:K480	1.44	No	No	0	8	8
272	R:R:I160	R:R:L157	1.43	No	No	0	8	5
273	R:R:L86	R:R:M90	1.41	No	No	0	6	5
274	R:R:K442	R:R:N443	1.4	No	No	0	3	4
275	R:R:H59	R:R:V52	1.38	No	No	0	8	8
276	R:R:D186	R:R:K442	1.38	No	No	0	3	3
277	R:R:L466	R:R:L470	1.38	No	No	0	7	8
278	R:R:L58	R:R:N474	1.37	Yes	No	0	9	9
279	R:R:L449	R:R:N446	1.37	No	No	0	4	6
280	R:R:H484	R:R:K480	1.31	No	No	0	6	8
281	R:R:D178	R:R:E177	1.3	No	No	0	3	3
282	R:R:R143	R:R:T140	1.29	No	No	0	9	9
283	R:R:H484	R:R:L483	1.29	No	No	0	6	8
284	R:R:F168	R:R:I160	1.26	No	No	0	6	8
285	R:R:K137	R:R:R134	1.24	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	11.8971	7	1	0
2	R:R:T41	5.9025	4	1	9
3	R:R:N45	4.745	4	0	9
4	R:R:E55	7.1975	4	4	8
5	R:R:L58	7.1625	4	4	9
6	R:R:Y65	6.98667	6	2	8
7	R:R:D73	8.425	4	0	9
8	R:R:V80	5.515	4	1	9
9	R:R:M81	6.4175	4	1	9
10	R:R:N84	6.71	5	1	8
11	R:R:W93	7.66333	6	1	9
12	R:R:R97	6.7825	4	0	5
13	R:R:W103	6.546	5	1	9
14	R:R:Y108	11.905	4	1	9
15	R:R:T112	8.26	5	1	9
16	R:R:F119	5.775	4	0	8
17	R:R:Y126	9.07	4	0	9
18	R:R:R139	8.1825	4	2	9
19	R:R:W152	4.516	5	0	9
20	R:R:W158	8.10167	6	1	8
21	R:R:W165	8.268	5	1	9
22	R:R:C180	6.6	4	1	9
23	R:R:F184	8.3175	4	1	9
24	R:R:Y185	7.2275	4	0	7
25	R:R:F190	7.54333	6	1	9
26	R:R:N198	7.636	5	1	9
27	R:R:F199	10.305	4	5	9
28	R:R:M206	4.525	4	0	9
29	R:R:F209	6.725	4	0	7
30	R:R:Y210	6.9525	4	0	9
31	R:R:R218	4.635	4	0	7
32	R:R:F424	4.91	5	5	9
33	R:R:W428	7.518	5	0	9
34	R:R:Y431	11.095	4	0	9
35	R:R:F432	10.975	4	0	9
36	R:R:W455	8.8575	4	1	9
37	R:R:Y458	6.50833	6	1	9
38	R:R:Y468	5.916	5	2	9
39	R:R:F475	9.68	5	0	9
40	R:R:F479	5.6325	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D107	62.5622	10.22	Yes	No	1	0	9
2	R:R:D107	R:R:Y458	32.5663	11.49	No	Yes	1	9	9
3	R:R:D107	R:R:V80	30.0166	7.3	No	Yes	1	9	9
4	R:R:V80	R:R:W103	24.4973	4.9	Yes	Yes	1	9	9
5	R:R:W103	R:R:W93	17.0346	6.56	Yes	Yes	1	9	9
6	R:R:L95	R:R:W93	11.7226	14.81	No	Yes	0	9	9
7	R:R:M81	R:R:Y458	12.8472	4.79	Yes	Yes	1	9	9
8	R:R:V76	R:R:V80	23.3831	4.81	No	Yes	1	9	9
9	R:R:S461	R:R:V76	45.5846	8.08	No	No	0	9	9
10	R:R:D73	R:R:S461	45.512	10.31	Yes	No	0	9	9
11	R:R:D73	R:R:N45	100	6.73	Yes	Yes	0	9	9
12	R:R:N45	R:R:P465	11.4998	6.52	Yes	No	0	9	9
13	R:R:V76	R:R:Y458	23.7355	3.79	No	Yes	1	9	9
14	L:L:?1	R:R:S111	16.8688	12.72	Yes	No	0	0	9
15	R:R:S111	R:R:W428	17.1124	3.71	No	Yes	0	9	9
16	R:R:N460	R:R:W428	66.1122	13.56	No	Yes	0	9	9
17	R:R:N460	R:R:N464	62.4223	9.54	No	No	0	9	9
18	R:R:D73	R:R:N464	61.1267	10.77	Yes	No	0	9	9
19	R:R:N45	R:R:S70	85.2301	2.98	Yes	No	0	9	9
20	R:R:S70	R:R:V48	80.9805	4.85	No	No	0	9	9
21	R:R:F479	R:R:V48	48.4401	5.24	Yes	No	0	9	9
22	R:R:F479	R:R:L47	18.4598	4.87	Yes	No	0	9	9
23	R:R:P469	R:R:V48	30.6851	7.07	No	No	0	9	9
24	R:R:L49	R:R:S70	26.3993	7.51	No	No	0	8	9
25	R:R:F475	R:R:P469	26.591	7.22	Yes	No	0	9	9
26	R:R:F475	R:R:L58	26.9227	14.61	Yes	Yes	0	9	9
27	R:R:E55	R:R:L58	13.3655	5.3	Yes	Yes	4	8	9
28	R:R:F475	R:R:F479	27.13	9.65	Yes	Yes	0	9	9
29	R:R:F475	R:R:N63	13.4225	8.46	Yes	No	0	9	9
30	L:L:?1	R:R:N198	27.6897	6.46	Yes	Yes	1	0	9
31	R:R:I115	R:R:N198	61.0645	5.66	No	Yes	0	9	9
32	R:R:F424	R:R:I115	65.6302	5.02	Yes	No	0	9	9
33	R:R:F424	R:R:V118	33.0276	6.55	Yes	No	0	9	9
34	R:R:V118	R:R:Y468	32.188	6.31	No	Yes	0	9	9
35	R:R:L121	R:R:Y468	34.9554	5.86	No	Yes	2	9	9
36	R:R:L121	R:R:Y65	34.8362	5.86	No	Yes	2	9	8
37	R:R:D124	R:R:Y65	25.4612	14.94	No	Yes	2	9	8
38	R:R:D124	R:R:R139	10.8157	11.91	No	Yes	2	9	9
39	R:R:I148	R:R:Y65	19.4704	3.63	No	Yes	0	9	8
40	R:R:I148	R:R:S68	18.9314	6.19	No	No	0	9	9
41	R:R:L49	R:R:V71	19.8901	2.98	No	No	0	8	6
42	R:R:V71	R:R:W152	18.5116	3.68	No	Yes	0	6	9
43	R:R:S68	R:R:W152	18.5375	6.18	No	Yes	0	9	9
44	R:R:N84	R:R:Y458	13.5158	8.14	Yes	Yes	1	8	9
45	L:L:?1	R:R:Y108	10.852	22.07	Yes	Yes	1	0	9
46	L:L:?1	R:R:W158	35.2042	7.5	Yes	Yes	1	0	8
47	R:R:F184	R:R:W158	52.2233	4.01	Yes	Yes	1	9	8
48	R:R:F184	R:R:W165	30.9857	9.02	Yes	Yes	1	9	9
49	R:R:D183	R:R:W165	23.7925	4.47	No	Yes	0	7	9
50	R:R:D183	R:R:R97	18.5272	3.57	No	Yes	0	7	5
51	R:R:L101	R:R:R97	10.7432	12.15	No	Yes	0	8	5
52	L:L:?1	R:R:T112	10.484	5.55	Yes	Yes	1	0	9
53	R:R:F116	R:R:T112	10.9608	6.49	No	Yes	0	8	9
54	R:R:F424	R:R:M206	50.767	3.73	Yes	Yes	0	9	9
55	R:R:F119	R:R:M206	20.1907	3.73	Yes	Yes	0	8	9
56	R:R:C122	R:R:M206	18.7396	4.86	No	Yes	0	8	9
57	R:R:C122	R:R:Y210	17.9156	13.44	No	Yes	0	8	9
58	R:R:D124	R:R:Y135	13.3914	6.9	No	No	2	9	9
59	R:R:R127	R:R:Y135	12.6036	20.58	No	No	0	8	9
60	R:R:R127	R:R:Y138	11.2251	2.06	No	No	0	8	8
61	R:R:F184	R:R:F190	20.8592	8.57	Yes	Yes	1	9	9
62	R:R:T194	R:R:W158	21.6573	7.28	No	Yes	0	8	8
63	R:R:F190	R:R:T194	19.346	10.38	Yes	No	0	9	8
64	R:R:F190	R:R:P161	20.3203	5.78	Yes	No	0	9	9
65	R:R:F435	R:R:Y431	16.4646	9.28	No	Yes	0	8	9
66	R:R:F435	R:R:K191	15.1379	16.13	No	No	0	8	9
67	R:R:I438	R:R:K191	13.8371	4.36	No	No	0	6	9
68	R:R:I438	R:R:Y185	10.1886	3.63	No	Yes	0	6	7
69	R:R:F432	R:R:N198	19.3512	7.25	Yes	Yes	0	9	9
70	R:R:F199	R:R:F432	20.8489	19.29	Yes	Yes	0	9	9
71	R:R:F199	R:R:Y200	14.0703	6.19	Yes	No	0	9	8
72	R:R:M436	R:R:Y200	12.3393	4.79	No	No	0	7	8
73	R:R:F432	R:R:Y431	16.3972	11.35	Yes	Yes	0	9	9
74	R:R:M206	R:R:M421	15.9567	5.78	Yes	No	0	9	9
75	R:R:L417	R:R:Y210	17.1901	4.69	No	Yes	0	9	9
76	R:R:I420	R:R:Y468	11.0748	6.04	No	Yes	0	9	9
77	R:R:L417	R:R:Y214	15.7649	3.52	No	No	0	9	8
78	R:R:R218	R:R:Y214	12.8109	2.06	Yes	No	0	7	8
79	R:R:I425	R:R:M421	13.1478	5.83	No	No	0	8	9
80	R:R:I425	R:R:I429	11.7278	2.94	No	No	0	8	8
81	R:R:I160	R:R:P161	15.2622	3.39	No	No	0	8	9
82	R:R:F190	R:R:M193	10.1835	2.49	Yes	No	0	9	7
83	R:R:N198	R:R:W158	42.4026	5.65	Yes	Yes	1	9	8
84	R:R:I115	R:R:W428	31.2759	5.87	No	Yes	0	9	9
85	R:R:F432	R:R:W428	21.2065	6.01	Yes	Yes	0	9	9
86	R:R:F199	R:R:F424	12.1839	5.36	Yes	Yes	5	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D107	10.22	1	Yes	No	0	9	0	1
L:L:?1	R:R:Y108	22.07	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:S111	12.72	1	Yes	No	0	9	0	1
L:L:?1	R:R:T112	5.55	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:W158	7.5	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:N198	6.46	1	Yes	Yes	0	9	0	1
L:L:?1	R:R:Y431	18.76	1	Yes	Yes	0	9	0	1
R:R:D107	R:R:V80	7.3	1	No	Yes	9	9	1	2
R:R:V80	R:R:Y458	5.05	1	Yes	Yes	9	9	2	2
R:R:D107	R:R:Y458	11.49	1	No	Yes	9	9	1	2
R:R:W158	R:R:Y108	14.47	1	Yes	Yes	8	9	1	1
R:R:I162	R:R:Y108	4.84	0	No	Yes	9	9	2	1
R:R:T182	R:R:Y108	6.24	0	No	Yes	9	9	2	1
R:R:S111	R:R:W428	3.71	0	No	Yes	9	9	1	2
R:R:F116	R:R:T112	6.49	0	No	Yes	8	9	2	1
R:R:S155	R:R:T112	6.4	0	No	Yes	9	9	2	1
R:R:T112	R:R:W158	9.7	1	Yes	Yes	9	8	1	1
R:R:N198	R:R:T112	13.16	1	Yes	Yes	9	9	1	1
R:R:I115	R:R:N198	5.66	0	No	Yes	9	9	2	1
R:R:I115	R:R:W428	5.87	0	No	Yes	9	9	2	2
R:R:F184	R:R:W158	4.01	1	Yes	Yes	9	8	2	1
R:R:T194	R:R:W158	7.28	0	No	Yes	8	8	2	1
R:R:N198	R:R:W158	5.65	1	Yes	Yes	9	8	1	1
R:R:F184	R:R:T182	11.67	1	Yes	No	9	9	2	2
R:R:F432	R:R:N198	7.25	0	Yes	Yes	9	9	2	1
R:R:F432	R:R:W428	6.01	0	Yes	Yes	9	9	2	2
R:R:F432	R:R:Y431	11.35	0	Yes	Yes	9	9	2	1
R:R:F435	R:R:Y431	9.28	0	No	Yes	8	9	2	1
R:R:T453	R:R:Y431	4.99	0	No	Yes	9	9	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	8YN2_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.63
Number of Linked Nodes	253
Number of Links	285
Number of Hubs	40
Number of Links mediated by Hubs	147
Number of Communities	6
Number of Nodes involved in Communities	44
Number of Links involved in Communities	58

Path Summary
Number Of Nodes in MetaPath	87
Number Of Links MetaPath	86
Number of Shortest Paths	49927
Length Of Smallest Path	3
Average Path Length	12.6696
Length of Longest Path	25
Minimum Path Strength	1.3
Average Path Strength	6.86743
Maximum Path Strength	20.415
Minimum Path Correlation	0.7
Average Path Correlation	0.921857
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.54545
Average % Of Corr. Nodes	48.5237
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.6898
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	HSM
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	HSM
Name	Histamine
Synonyms	1H-Imidazole-4-ethanamine
Identifier
Formula	C5 H9 N3
Molecular Weight	111.145
SMILES
PubChem	774
Formal Charge	0
Total Atoms	17
Total Chiral Atoms	0
Total Bonds	17
Total Aromatic Bonds	5


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P35367
Sequence	>8YN2_nogp_Chain_R M P L V V V L S T I C L V T V G L N L L V L Y A V R S E R K L H T V G N L Y I V S L S V A D L I V G A V V M P M N I L Y L L M S K W S L G R P L C L F W L S M D Y V A S T A S I F S V F I L C I D R Y R S V Q Q P L R Y L K Y R T K T R A S A T I L G A W F L S F L W V I P I L G W N H F M V R R E D K C E T D F Y D V T W F K V M T A I I N F Y L P T L L M L W F Y A K I Y K A V R Q H C Q H R E N R E R K A A K Q L G F I M A A F I L C W I P Y F I F F M V I A F C K N C C N E H L H M F T I W L G Y I N S T L N P L I Y P L C N E N F K K T F K R I L H I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8GH1	A	Amine	Adrenergic	β₂	Homo sapiens	Constrained Epinephrine	-	-	4.1	2024-03-06	doi.org/10.1038/s41586-024-07153-1
	2RH1	A	Amine	Adrenergic	β₂	Homo sapiens	S-Carazolol	-	-	2.4	2007-10-30	doi.org/10.1126/science.1150577
	3RZE	A	Amine	Histamine	H₁	Homo sapiens	Cidoxepin	-	-	3.1	2011-06-15	doi.org/10.1038/nature10236
	7DFL	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-	chim(NtGi1L-Gq)/β1/γ2	3.3	2021-03-31	doi.org/10.1038/s41467-021-22427-2
	7DFL (No Gprot)	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-		3.3	2021-03-31	doi.org/10.1038/s41467-021-22427-2
	8X5X	A	Amine	Histamine	H₁	Homo sapiens	-	-	-	3.5	2024-01-17	doi.org/10.1038/s41467-023-44477-4
	8X5Y	A	Amine	Histamine	H₁	Homo sapiens	Astemizole	-	-	3	2024-01-17	doi.org/10.1038/s41467-023-44477-4
	8X63	A	Amine	Histamine	H₁	Homo sapiens	Mepyramine	-	-	3.2	2024-01-17	doi.org/10.1038/s41467-023-44477-4
	8X64	A	Amine	Histamine	H₁	Homo sapiens	Desloratadine	-	-	3.4	2024-01-17	doi.org/10.1038/s41467-023-44477-4
	8YN2	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.66	2024-10-09	doi.org/10.1038/s41467-024-52585-y
	8YN2 (No Gprot)	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-		2.66	2024-10-09	doi.org/10.1038/s41467-024-52585-y
	9LRD	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-	Gi1/β1/γ2	3.23	2025-06-11	To be published
	9LRD (No Gprot)	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-		3.23	2025-06-11	To be published
	9LRB	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-	Gs/β1/γ2	2.77	2025-06-11	To be published
	9LRB (No Gprot)	A	Amine	Histamine	H₁	Homo sapiens	Histamine	-		2.77	2025-06-11	To be published
	8WSS	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	Pro-MCH	-	Gi1/β1/γ1	3.01	2024-06-19	doi.org/10.1038/s41421-024-00679-8
	8WSS (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	Pro-MCH	-		3.01	2024-06-19	doi.org/10.1038/s41421-024-00679-8
	8YNS	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	SNAP-94847	-	-	3.33	2024-12-18	doi.org/10.1038/s41421-024-00754-0
	8YNT	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	SNAP-94847	-	-	3.43	2024-12-18	doi.org/10.1038/s41421-024-00754-0
	8WWK	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.61	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWK (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.61	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWL	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.78	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWL (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.78	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWM	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.81	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWM (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.81	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWN	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-	Gi1/β1/γ2	2.65	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWN (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	MCH	-		2.65	2024-11-13	doi.org/10.1038/s41421-024-00754-0
	8WWH	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-	Gi1/β1/γ2	2.84	2024-11-13	To be published
	8WWH (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-		2.84	2024-11-13	To be published
	8WWI	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-	Gi1/β1/γ2	3.43	2024-11-13	To be published
	8WWI (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-		3.43	2024-11-13	To be published
	8WWJ	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-	Gi1/β1/γ2	3.03	2024-11-13	To be published
	8WWJ (No Gprot)	A	Peptide	Melanin Concentrating Hormone	MCH1	Homo sapiens	-	-		3.03	2024-11-13	To be published
	8GW8	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	PCO371	Gs/β1/γ2	2.9	2023-06-14	doi.org/10.1038/s41586-023-06169-3
	8GW8 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	PCO371		2.9	2023-06-14	doi.org/10.1038/s41586-023-06169-3
	8JR9	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	PCO371	chim(NtGi1-Gs)/β1/γ2	2.57	2023-08-02	doi.org/10.1038/s41586-023-06467-w
	8JR9 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	-	PCO371		2.57	2023-08-02	doi.org/10.1038/s41586-023-06467-w
	7VVJ	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/β1/γ2	3.2	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVJ (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-		3.2	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVK	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	3.3	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVK (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.3	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVL	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	2.8	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVL (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.8	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVM	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	3.2	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVM (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.2	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVN	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	3.8	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVN (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.8	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVO	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	4.1	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	7VVO (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		4.1	2022-08-03	doi.org/10.1016/j.molcel.2022.07.003
	8FLQ	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	Gs/β1/γ2	2.55	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLQ (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.55	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLR	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	Gs/β1/γ2	2.94	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLR (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-		2.94	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLS	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/β1/γ2	3.09	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLS (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-		3.09	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLT	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	M-PTH(1-14)	-	Gs/β1/γ2	3.03	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLT (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	M-PTH(1-14)	-		3.03	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLU	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH	-	Gs/β1/γ2	2.76	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8FLU (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH	-		2.76	2023-04-26	doi.org/10.1016/j.str.2023.04.002
	8HA0	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/β1/γ2	2.62	2022-12-21	doi.org/10.1038/s41401-022-01032-z
	8HA0 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.62	2022-12-21	doi.org/10.1038/s41401-022-01032-z
	8HAF	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-	chim(NtGi1-Gs)/β1/γ2	3.25	2022-12-21	doi.org/10.1038/s41401-022-01032-z
	8HAF (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTHrP(1-36)	-		3.25	2022-12-21	doi.org/10.1038/s41401-022-01032-z
	8HAO	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1-Gs)/β1/γ2	3.76	2022-12-21	doi.org/10.1038/s41401-022-01032-z
	8HAO (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		3.76	2022-12-21	doi.org/10.1038/s41401-022-01032-z
	6FJ3	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	-	2.5	2018-11-21	doi.org/10.1038/s41594-018-0151-4
	6NBF	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-	Gs/β1/γ2	3	2019-04-17	doi.org/10.1126/science.aav7942
	6NBF (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-		3	2019-04-17	doi.org/10.1126/science.aav7942
	6NBH	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-	Gs/β1/γ2	3.5	2019-04-17	doi.org/10.1126/science.aav7942
	6NBH (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-		3.5	2019-04-17	doi.org/10.1126/science.aav7942
	6NBI	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-	Gs/β1/γ2	4	2019-04-17	doi.org/10.1126/science.aav7942
	6NBI (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH Analog	-		4	2019-04-17	doi.org/10.1126/science.aav7942
	9B5Y	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH	-	chim(NtGi1-Gq)/β1/γ2	3.49	2025-03-19	doi.org/10.1073/pnas.2426178122
	9B5Y (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Long-Acting PTH	-		3.49	2025-03-19	doi.org/10.1073/pnas.2426178122
	7Y35	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-	Gs/β1/γ2	2.9	2023-07-05	To be published
	7Y35 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Abaloparatide	-		2.9	2023-07-05	To be published
	7Y36	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Teriparatide	-	Gs/β1/γ2	2.8	2023-07-05	To be published
	7Y36 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	Teriparatide	-		2.8	2023-07-05	To be published
	9JR2	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.8	2024-10-16	To be published
	9JR2 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.8	2024-10-16	To be published
	9JR3	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-	chim(NtGi1L-Gs-CtGq)/β1/γ2	2.8	2024-10-16	To be published
	9JR3 (No Gprot)	B1	Peptide	Parathyroid Hormone	PTH1	Homo sapiens	PTH	-		2.8	2024-10-16	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 8YN2_nogp.zip

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