psnGPCRdb

Ligands

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

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Name: Name of the corresponding Consensus network.

Description: Breif description of the networks involved in the corresponding consensus.



ShowIdMembers
5ht1_off5ht1b_off
5ht1_on5ht1a_on
5ht1d_on
5ht1e_on
5ht1f_on
5ht1b_on
5ht1a_on8JSP-5-HT1A-Ulotaront-Gi1/&β;1/&γ;2
7E2Z-5-HT1A-Aripiprazole-Gi1/&β;1/&γ;2
8W8B-5-HT1A-SEP-363856-Gi1/&β;1/&γ;2
7E2Y-5-HT1A-Serotonin-Gi1/&β;1/&γ;2
5ht1b_off5V54-5-HT1B-Methiothepin
5ht1b_on6G79-5-HT1B-Donitriptan-Go/&β;1/&γ;2
5ht1d_on7E32-5-HT1D-Serotonin-Gi1/&β;1/&γ;2
5ht1e_on7E33-5-HT1E-BRL-54443-Gi1/&β;1/&γ;2
5ht1f_on7EXD-5-HT1F-Lasmiditan-Gi1/&β;1/&γ;2
5ht2_off5ht2a_off
5ht2b_off
5ht2c_off
5ht2_on5ht2a_on
5ht2c_on
5ht2a_off6A94-5-HT2A-Zotepine
6WH4-5-HT2A-Methiothepin
7VOE-5-HT2A-Aripiprazole
7VOD-5-HT2A-Cariprazine
7WC8-5-HT2A-Lumateperone
6A93-5-HT2A-Risperidone
5ht2a_on7RAN-5-HT2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6WHA-5-HT2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5ht2b_off6DRZ-5-HT2B-Methysergide
6DRX-5-HT2B-Lisuride
5ht2c_off6BQH-5-HT2C-Ritanserin
5ht2c_on8DPF-5-HT2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8DPG-5-HT2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5ht4_on7XT8-5-HT4-Serotonin-Gs/&β;1/&γ;2
5ht5_off5ht5a_off
5ht5_on5ht5a_on
5ht5a_off7UM4-5-HT5A-AS2674723
5ht5a_on7UM5-5-HT5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
7UM6-5-HT5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
7UM7-5-HT5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
5ht6_on7XTB-5-HT6-Serotonin-Gs/&β;1/&γ;2
8JLZ-5-HT6-ST1936-Gs/&β;1/&γ;2
5ht7_on7XTC-5-HT7-5-CT-Gs/&β;1/&γ;2
5ht_off5ht2_off
5ht5_off
5ht1_off
5ht_on5ht1_on
5ht2_on
5ht4_on
5ht5_on
5ht6_on
5ht7_on
a1_off5UEN-A1-DU172
5N2S-A1-PSB36
a1_on7LD4-A1-Adenosine-Gi2/&β;1/&γ;2
a1_on_allo7LD3-A1-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
a2_offa2a_off
a2_ona2a_on
a2b_on
a2a_off8C9W-A2A-Etrumadenant
3UZA-A2A-GTPL9236
8GNG-A2A-Istradefylline
5UIG-A2A-J3.651.884G
8CU6-A2A-LJ-4517
7PX4-A2A-PSB-2113
7PYR-A2A-PSB-2115
8DU3-A2A-PubChem 105526064
8JWY-A2A-PubChem 168451710
5K2D-A2A-ZM241385
a2a_off_allo6ZDR-A2A-HMS1413f12-Na
6GT3-A2A-Imaradenant-Na
8CU7-A2A-LJ-4517-Na
5OLV-A2A-LUAA41063-Na
5N2R-A2A-PubChem 92460631; psb36-Na
5MZJ-A2A-Theophylline-Na
5OLO-A2A-Tozadenant-Na
5OLH-A2A-Vipadenant-Na
5NM4-A2A-ZM241385-Na
8GNE-A2A-KW-6356-Na
8JWZ-A2A-AB928-Na
5MZP-A2A-Caffeine-Na
8CIC-A2A-Etrumadenant-Na
a2a_on6GDG-A2A-NECA-Gs/&β;1/&γ;1
a2b_on8HDP-A2B-Adenosine-Gs/&β;1/&γ;2
8HDO-A2B-BAY 60-6583-Gs/&β;1/&γ;2
7XY7-A2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
7XY6-A2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
adenosine_offa1_off
a2_off
adenosine_ona1_on
a2_on
adgrf1_on_allo7WU5-ADGRF1-K6G-Gi1/&β;1/&γ;2
8G2Y-ADGRF1-LPC-chim(Gs-CtGq)/&β;1/&γ;2
adgrg2_on7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
adgrg3_on7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
adgrg_onadgrg2_on
adgrg3_on
adrenergic_offbeta_off
alpha_off
adrenergic_onbeta_on
alpha_on
alpha1_offalpha1a_off
alpha1b_off
alpha1_onalpha1a_on
alpha1a_off7YMJ-Alpha1A-Tamsulosin
8HN1-Alpha1A-Toxin AdTx1
alpha1a_on7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
alpha1b_off7B6W-α1b-Cyclazosin
alpha2_offalpha2a_off
alpha2c_off
alpha2_onalpha2a_on
alpha2b_on
alpha2a_off6KUX-α2a-RS-79948
alpha2a_on7EJ0-α2a-L-Norepinephrine-Go/&β;1/&γ;2
7EJK-α2a-Oxymetazoline-Go/&β;1/&γ;2
7W7E-α2a-W58-Go/&β;1/&γ;2
7W6P-α2a-W96-Go/&β;1/&γ;2
7EJ8-α2a-Brimonidine-Go/&β;1/&γ;2
7EJA-α2a-Dexmedetomidine-Go/&β;1/&γ;2
alpha2b_on6K41-α2b-Dexmedetomidine-Go/&β;1/&γ;2
alpha2c_off6KUW-α2c-PubChem 57213234
alpha_offalpha1_off
alpha2_off
alpha_onalpha1_on
alpha2_on
amine_offadrenergic_off
histamine_off
muscarinic_off
5ht_off
dopamine_off
amine_onadrenergic_on
histamine_on
muscarinic_on
tar_on
5ht_on
dopamine_on
angiotensin_offat1_off
at2_off
angiotensin_onat1_on
apelin_on7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
arrestin15W0P-Rhodopsin-Arrestin1
arrestin26TKO-β1-Arformoterol-Arrestin2
6PWC-NTS1-Neurotensin-Arrestin2
7R0C-V2-AVP-Arrestin2
at1_off4YAY-AT1-ZD-7155
4ZUD-AT1-Olmesartan
at1_on7F6G-AT1-SAR1-AngII-Gq/&β;1/&γ;2
at2_off7JNI-AT2-Olodanrigan
bb1_on8H0P-BB1-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
bb2_off7W41-BB2-PD176252
bb2_on7W40-BB2-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
7W3Z-BB2-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
beta1_off2VT4-β1-Cyanopindolol
2YCZ-β1-Iodocyanopindolol
beta1_off_allo4BVN-β1-Cyanopindolol-Na
beta1_on7JJO-β1-Isoprenaline-Gs/&β;1/&γ;2
8DCR-β1-Dobutamine-Gs/&β;1/&γ;2
beta2_off6PS2-β2-(S)-Alprenolol
6PS3-β2-(S)-Carvedilol
6PS5-β2-(S)-Propranolol
6PS6-β2-Timolol
2RH1-β2-(S)-Carazolol
6PS4-β2-ICI 118-551
3NY9-β2-PubChem 913103
beta2_off_allo6OBA-β2-(S)-Alprenolol-GTPL11074
beta2_on3SN6-β2-BI167107-Gs/&β;1/&γ;2
7DHR-β2-Isoprenaline-Gs/&β;1/&γ;2
7BZ2-β2-Arformoterol-Gs/&β;1/&γ;2
7DHI-β2-Salbutamol-Gs/&β;1/&γ;2
beta3_on7DH5-β3-Mirabegron-Gs/&β;1/&γ;2
7XJH-β3-Isoproterenol-Gs/&β;1/&γ;2
beta_offbeta1_off
beta2_off
beta_onbeta1_on
beta2_on
beta3_on
bileacid_on7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
7CFM-GPBA-P395-Gs/&β;1/&γ;2
7XTQ-GPBA-R399-Gs/&β;1/&γ;2
bk1_on7EIB-BK1-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
bk2_on7F2O-BK2-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7F6I-BK2-Kallidin-Gq/&β;1/&γ;2
blt1_off7K15-BLT1-MKD046-Na
blt1_on7VKT-BLT1-LTB4-Gi1/&β;1/&γ;2
blt_offblt1_off
blt_onblt1_on
bombesin_offbb2_off
bombesin_onbb2_on
bb1_on
bradykinin_onbk2_on
bk1_on
c3a_on8HK2-C3aB-C3a anaphylatoxin-Gi1/&β;1/&γ;2
8IA8-C3aB-E7 peptide-Gi1/&β;1/&γ;2
8J6D-C3aB-EP141-Go/&β;1/&γ;2
8I95-C3aB-EP54-Go/&β;1/&γ;2
c5a1_off_ortoallo6C1Q-C5a1-PMX53-NDT9513727
6C1R-C5a1-PMX53-Avacopan; Na
c5a1_on7Y65-C5a1-C5a peptide-Gi1/&β;1/&γ;2
8HK5-C5a1-Complement C5-Gi1/&β;1/&γ;2
7Y66-C5a1-BM213-Gi1/&β;1/&γ;2
7Y67-C5a1-C089 peptide-Gi1/&β;1/&γ;2
7Y64-C5a1-C5a anaphylatoxin-Gi1/&β;1/&γ;2
calcitonin_onct_on
ctlike_on
cannabinoid_offcb1_off
cb2_off
cannabinoid_oncb1_on
cb2_on
cb1_off5TGZ-CB1-AM6538
5U09-CB1-Taranabant
cb1_off_allo6KQI-CB1-PubMed 104895-ORG27569
cb1_on8GHV-CB1-PubChem 145964903-Gi1/&β;1/&γ;2
6KPG-CB1-AM841-Gi1/&β;1/&γ;2
6N4B-CB1-MDMB-Fubinaca-Gi1/&β;1/&γ;2
cb1_on_allo7WV9-CB1-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
cb2_off5ZTY-CB2-AM10257
cb2_on8GUS-CB2-HU-308-Gi1/&β;1/&γ;2
8GUT-CB2-LEI-102-Gi1/&β;1/&γ;2
8GUQ-CB2-Olorinab-Gi1/&β;1/&γ;2
8GUR-CB2-PubChem 104895-Gi1/&β;1/&γ;2
6KPF-CB2-PubChem 145915889-Gi1/&β;1/&γ;2
6PT0-CB2-WIN 55212-2-Gi1/&β;1/&γ;2
cck_offccka_off
cck_onccka_on
cckb_on
ccka_off7F8Y-CCKA-Devazepide
7F8U-CCKA-Lintitript
ccka_on7EZH-CCKA-Cholecystokinin-8-Gi1/&β;1/&γ;2
7XOV-CCKA-SR146131-Gs/&β;1/&γ;2
cckb_on7XOW-CCKB-Gastrin-Gq/&β;1/&γ;2
7F8W-CCKB-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
8IA7-CCKB-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
ccr1_on7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
ccr2_off_allo5T1A-CCR2-PubChem 68764898; PubChem 12093170
6GPX-CCR2-MK0812
ccr2_on7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
ccr5_off5UIW-CCR5-5P7-CCL5
ccr5_on7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
ccr6_on6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
ccr7_off_allo6QZH-CCR7-HY-133073; Na
ccr8_off8TLM-CCR8-Anti-murine CCR8 antibody
ccr8_on8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
ccr9_off_allo5LWE-CCR9-Vercirnon
ccr_offccr5_off
ccr8_off
ccr_onccr5_on
ccr6_on
ccr1_on
ccr2_on
ccr8_on
chemerin_oncml1_on
chemokine_offcxcr_off
chemokine_oncxcr_on
cx3cr_on
class-a_offsensory_off
amine_off
lipid_off
nucleotide_off
peptide_off
protein_off
hcar_off
class-a_onsensory_on
amine_on
lipid_on
nucleotide_on
peptide_on
protein_on
hcar_on
steroid_on
melatonin_on
class-b1_onglucagon_on
calcitonin_on
vip-pacap_on
pth_on
crf_on
class-b2_onadgrg_on
class-c_offgabab_off
mglu_off
class-c_ongabab_on
mglu_on
class-d_offste2_off
class-d_onste2_on
class-f_offsmo_off
class-t_ontaste2_on
cml1_on8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
compl-peptide_onc5a1_on
c3a_on
crf1_on6P9X-CRF1-Corticoliberin-Gs/&β;1/&γ;2
crf2_on7TS0-CRF2-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
crf_oncrf2_on
crf1_on
ct_on7TYL-CT-Amylin-Gs/&β;1/&γ;2
7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
ctlike_on6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
cx3cr1_on7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
cx3cr_oncx3cr1_on
cxcr1_on8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
cxcr2_on6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
cxcr4_off4RWS-CXCR4-vMIP-II
cxcr_offcxcr4_off
cxcr_oncxcr1_on
cxcr2_on
cyslt1_off_ortoallo6RZ5-CysLT1-Zafirlukast-Na
6RZ4-CysLT1-Pranlukast-Na
cyslt2_off6RZ6-CysLT2-ONO-2570366
6RZ9-CysLT2-ONO-2770372
6RZ8-CysLT2-ONO-2080365
cyslt_offcyslt2_off
d1_on7F0T-D1-Dopamine-Gs/&β;1/&γ;2
7CKY-D1-PW0464-Gs/&β;1/&γ;2
8IRR-D1-Rotigotine-Gs/&β;1/&γ;2
7JV5-D1-SKF81297-Gs/&β;1/&γ;2
7JVP-D1-SKF83959-Gs/&β;1/&γ;2
7X2D-D1-Tavapadon-Gs/&β;1/&γ;2
7JOZ-D1-VFP-Gs/&β;1/&γ;2
7CKX-D1-A77636-Gs/&β;1/&γ;2
7JVQ-D1-Apomorphine-Gs/&β;1/&γ;2
d1_on_allo7LJC-D1-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
7CKZ-D1-Dopamine-Mevidalen-Gs/&β;1/&γ;2
d2_off6CM4-D2-Risperidone
6LUQ-D2-Haloperidol
7DFP-D2-Spiperone
d2_on7JVR-D2-Bromoergocryptine-Gi1/&β;1/&γ;2
8IRS-D2-Rotigotine-Gi1/&β;1/&γ;2
d3_off3PBL-D3-Eticlopride
d3_on8IRT-D3-Rotigotine-Gi1/&β;1/&γ;2
7CMV-D3-PD128907-Gi1/&β;1/&γ;2
7CMU-D3-Pramipexole-Gi1/&β;1/&γ;2
d4_off5WIU-D4-Nemonapride
d4_off_allo5WIV-D4-Nemonapride-Na
d5_on8IRV-D5-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
dop_off4EJ4-δ-Naltrindole
dop_off_allo4N6H-δ-Naltrindole-Na
dop_on8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
dopamine_offd3_off
d2_off
d4_off
dopamine_ond3_on
d2_on
d5_on
d1_on
dp2_off6D27-DP2-CAY10471
6D26-DP2-Fevipiprant
dp_offdp2_off
endothelin_offetb_off
endothelin_onetb_on
eta_on
ep2_on7CX4-EP2-Evatanepag-Gs/&β;1/&γ;2
7CX2-EP2-PGE2-Gs/&β;1/&γ;2
7CX3-EP2-Taprenepag-Gs/&β;1/&γ;2
ep3_on8GDC-EP3-PGE2-Gi1/&β;1/&γ;2
ep4_off5YWY-EP4-ONO-AE3-208
5YHL-EP4-PubChem 135121352
ep4_on7D7M-EP4-Dinoprostone-Gs/&β;1/&γ;1
8GCP-EP4-PGE2-Gi1/&β;1/&γ;2
8GD9-EP4-Rivenprost-Gs/&β;1/&γ;2
8GDA-EP4-L902688-Gs/&β;1/&γ;2
ep_offep4_off
ep_onep4_on
ep2_on
ep3_on
eta_on8HCQ-ETA-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
etb_off5XPR-ETB-Bosentan
6K1Q-ETB-IRL2500
5X93-ETB-K-8794
etb_on8HCX-ETB-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8HBD-ETB-IRL1620-Gi1/&β;1/&γ;2
ffa1_on8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
ffa2_on8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
ffa3_on8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
ffa3_on_allo8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
ffa4_on8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
ffa4_on_allo8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
ffa_onffa4_on
ffa1_on
ffa2_on
ffa3_on
fpa_on8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
fpr-alx_onfpr1-alx_on
fpr2-alx_on
fpr1-alx_on7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
fpr2-alx_on7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
fsh_on_allo8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
gabab_off7C7S-GABAB1, GABAB2-CGP54626
7CUM-GABAB1, GABAB2-CGP54626-Phospholipid
6W2X-GABAB1, GABAB2-PubChem 5311042-PubChem 23727970
gabab_on7EB2-GABAB1, GABAB2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
gal1_on7WQ3-GAL1-Galanin-Gi1/&β;1/&γ;2
gal2_on7WQ4-GAL2-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7XJL-GAL2-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
galanin_ongal2_on
gal1_on
ghrelin_off6KO5-Ghrelin-PubChem 57400002
7F83-Ghrelin-PF-05190457
ghrelin_on7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
ghrh_on7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
gi_5ht7E2Y-5-HT1A-Serotonin-Gi1/&β;1/&γ;2
8JSP-5-HT1A-Ulotaront-Gi1/&β;1/&γ;2
7E32-5-HT1D-Serotonin-Gi1/&β;1/&γ;2
7E33-5-HT1E-BRL-54443-Gi1/&β;1/&γ;2
7EXD-5-HT1F-Lasmiditan-Gi1/&β;1/&γ;2
7XTA-5-HT4-Serotonin-Gi1/&β;1/&γ;2
7X5H-5-HT5A-5-CT-Gi1/&β;1/&γ;2
7E2Z-5-HT1A-Aripiprazole-Gi1/&β;1/&γ;2
8W8B-5-HT1A-SEP-363856-Gi1/&β;1/&γ;2
gi_adrenergic7S0F-β1-Isoprenaline-Gi1/&β;1/&γ;2
6K42-α2b-Dexmedetomidine-Gi1/&β;1/&γ;2
gi_aminegi_5ht
gi_adrenergic
gi_dopamine
gi_muscarinic
gi_histamine
gi_apelin7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
gi_cannabinoid8GUS-CB2-HU-308-Gi1/&β;1/&γ;2
8GUT-CB2-LEI-102-Gi1/&β;1/&γ;2
8GUQ-CB2-Olorinab-Gi1/&β;1/&γ;2
8GUR-CB2-PubChem 104895-Gi1/&β;1/&γ;2
6KPF-CB2-PubChem 145915889-Gi1/&β;1/&γ;2
6PT0-CB2-WIN 55212-2-Gi1/&β;1/&γ;2
6KPG-CB1-AM841-Gi1/&β;1/&γ;2
6N4B-CB1-MDMB-Fubinaca-Gi1/&β;1/&γ;2
8GHV-CB1-PubChem 145964903-Gi1/&β;1/&γ;2
gi_cck7EZH-CCKA-Cholecystokinin-8-Gi1/&β;1/&γ;2
7F8V-CCKB-Gastrin-17-Gi2/&β;1/&γ;2
gi_chemerin8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
gi_chemokine7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
gi_class-agi_amine
gi_lipid
gi_melatonin
gi_peptide
gi_protein
gi_nucleotide
gi_hcar
gi_class-cgi_mglu
gi_gaba
gi_class-dgi_ste
gi_class-fgi_frizzled
gi_compl-peptide8HK5-C5a1-Complement C5-Gi1/&β;1/&γ;2
8IA8-C3aB-E7 peptide-Gi1/&β;1/&γ;2
7Y66-C5a1-BM213-Gi1/&β;1/&γ;2
7Y67-C5a1-C089 peptide-Gi1/&β;1/&γ;2
8HK2-C3aB-C3a anaphylatoxin-Gi1/&β;1/&γ;2
7Y64-C5a1-C5a anaphylatoxin-Gi1/&β;1/&γ;2
7Y65-C5a1-C5a peptide-Gi1/&β;1/&γ;2
gi_dopamine8IRT-D3-Rotigotine-Gi1/&β;1/&γ;2
7JVR-D2-Bromoergocryptine-Gi1/&β;1/&γ;2
8IRS-D2-Rotigotine-Gi1/&β;1/&γ;2
7CMV-D3-PD128907-Gi1/&β;1/&γ;2
7CMU-D3-Pramipexole-Gi1/&β;1/&γ;2
gi_endothelin8IY5-ETB-Endothelin-1-Gi1/&β;1/&γ;2
8HBD-ETB-IRL1620-Gi1/&β;1/&γ;2
gi_ffa8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
gi_formylpeptide7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
gi_frizzled6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
gi_gaba7EB2-GABAB1, GABAB2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
gi_galanin7WQ3-GAL1-Galanin-Gi1/&β;1/&γ;2
gi_ghrelin7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
gi_hca8H2G-HCA2-Niacin-Gi1/&β;1/&γ;2
8IHJ-HCA3-Acifran-Gi1/&β;1/&γ;2
8IHI-HCA2-Acifran-Gi1/&β;1/&γ;2
8IHB-HCA2-GSK256073-Gi1/&β;1/&γ;2
8IHH-HCA2-LUF6283-Gi1/&β;1/&γ;2
8IHF-HCA2-MK6892-Gi1/&β;1/&γ;2
8JIM-HCA2-MMF-Gi1/&β;1/&γ;2
8IJB-HCA2-Acipimox-Gi1/&β;1/&γ;2
8IJD-HCA2-MK6892-Gi1/&β;1/&γ;2
gi_hcargi_hca
gi_histamine8HN8-H4-Histamine-Gi1/&β;1/&γ;2
8HOC-H4-Imetit-Gi1/&β;1/&γ;2
gi_leukotriene7VKT-BLT1-LTB4-Gi1/&β;1/&γ;2
gi_lipidgi_cannabinoid
gi_prostanoid
gi_ffa
gi_lpl
gi_leukotriene
gi_lpl7EW3-S1P3-S1P-Gi1/&β;1/&γ;2
7TD4-S1P1-Siponimod-Gi1/&β;1/&γ;2
7VIF-S1P1-(S)-FTY720-P-Gi1/&β;1/&γ;2
7EO4-S1P1-BAF312-Gi1/&β;1/&γ;2
7VIG-S1P1-CBP-307-Gi1/&β;1/&γ;2
7EVZ-S1P1-Cenerimod-Gi1/&β;1/&γ;2
7EW4-S1P3-CYM5541-Gi1/&β;1/&γ;2
7EW2-S1P3-Fingolimod-Gi1/&β;1/&γ;2
7TD0-LPA1-LPA-Gi1/&β;1/&γ;2
7YU3-LPA1-ONO-0740556-Gi1/&β;1/&γ;2
7EW0-S1P1-Ozanimod-Gi1/&β;1/&γ;2
7EW7-S1P1-PubChem 4077460-Gi1/&β;1/&γ;2
gi_melatonin7VGY-MT1-2-Iodomelatonin-Gi1/&β;1/&γ;2
7DB6-MT1-Ramelteon-Gi1/&β;1/&γ;2
7VH0-MT2-Ramelteon-Gi1/&β;1/&γ;1
gi_mglu7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
gi_muscarinic7TRS-M4-Acetylcholine-Gi1/&β;1/&γ;2
7TRK-M4-Iperoxo-Gi1/&β;1/&γ;2
7V6A-M4-PubChem 9864275-Gi1/&β;1/&γ;2
gi_neuromedin7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
gi_neuropeptide7YOO-Y2-Neuropeptide Y-Gi1/&β;1/&γ;2
7YON-Y2-Peptide YY(3-36)-Gi1/&β;1/&γ;2
7X9C-Y4-Pancreatic Hormone-Gi1/&β;1/&γ;2
7X9A-Y1-Neuropeptide Y-Gi1/&β;1/&γ;2
gi_neurotensin7L0P-NTS1-Neurotensin-Gi1/&β;1/&γ;1
6OS9-NTS1-JMV449-Gi1/&β;1/&γ;2
gi_nucleotide7LD4-A1-Adenosine-Gi2/&β;1/&γ;2
gi_opioid8EF6-μ-Morphine-Gi1/&β;1/&γ;2
8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
7SCG-μ-FH210-Gi1/&β;1/&γ;2
7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
8DZP-κ-momSalB-Gi1/&β;1/&γ;2
8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
8EFO-μ-PZM21-Gi1/&β;1/&γ;2
8EFL-μ-SR17018-Gi1/&β;1/&γ;2
gi_peptidegi_opioid
gi_endothelin
gi_formylpeptide
gi_galanin
gi_ghrelin
gi_neuromedin
gi_neurotensin
gi_relaxin
gi_neuropeptide
gi_somatostatin
gi_apelin
gi_compl-peptide
gi_cck
gi_prostanoid8GCP-EP4-PGE2-Gi1/&β;1/&γ;2
8GDC-EP3-PGE2-Gi1/&β;1/&γ;2
8GCM-EP4-L902688-Gi1/&β;1/&γ;2
gi_proteingi_chemokine
gi_chemerin
gi_relaxin7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
gi_somatostatin7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
gi_ste7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
gip_on7DTY-GIP-GIP-Gs/&β;1/&γ;2
7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
gip_on_allo7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
glp1_on6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
glp1_on_allo6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
glp2_on7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
glp_onglp1_on
glp2_on
glu_on6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
glucagon_ongip_on
glu_on
secretin_on
ghrh_on
glp_on
gnrh1_off7BR3-GnRH1-Elagolix
gnrh_offgnrh1_off
go_5ht6G79-5-HT1B-Donitriptan-Go/&β;1/&γ;2
7UM5-5-HT5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
7UM6-5-HT5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
7UM7-5-HT5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
go_adhesion7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
go_adrenergic7EJ0-α2a-L-Norepinephrine-Go/&β;1/&γ;2
7EJK-α2a-Oxymetazoline-Go/&β;1/&γ;2
7W7E-α2a-W58-Go/&β;1/&γ;2
7W6P-α2a-W96-Go/&β;1/&γ;2
6K41-α2b-Dexmedetomidine-Go/&β;1/&γ;2
7EJ8-α2a-Brimonidine-Go/&β;1/&γ;2
7EJA-α2a-Dexmedetomidine-Go/&β;1/&γ;2
go_aminego_adrenergic
go_muscarinic
go_5ht
go_chemokine6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
go_class-ago_amine
go_peptide
go_protein
go_class-bgo_class-b1
go_class-b2
go_class-b1go_crf
go_class-b2go_adhesion
go_compl-peptide8I95-C3aB-EP54-Go/&β;1/&γ;2
8IA2-C5a1-C5a anaphylatoxin-Go/&β;1/&γ;2
8I9L-C3aB-C3a anaphylatoxin-Go/&β;1/&γ;2
8J6D-C3aB-EP141-Go/&β;1/&γ;2
go_crf7TS0-CRF2-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
go_galanin7XJJ-GAL1-Galanin-Go/&β;1/&γ;2
go_ghrelin7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
go_muscarinic8E9X-M4-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
7T8X-M2-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
go_opioid8DZQ-κ-momSalB-Go/&β;1/&γ;2
go_peptidego_opioid
go_ghrelin
go_compl-peptide
go_galanin
go_vasopressin
go_proteingo_chemokine
go_vasopressin7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
gphr_onlh_on
tsh_on
gpr119_on7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
gq_aminegq_muscarinic
gq_histamine
gq_angiotensin7F6G-AT1-SAR1-AngII-Gq/&β;1/&γ;2
gq_bombesin7W40-BB2-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
7W3Z-BB2-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
gq_bradykinin7F6H-BK2-Bradykinin-Gq/&β;1/&γ;2
7F6I-BK2-Kallidin-Gq/&β;1/&γ;2
gq_cck8IA7-CCKB-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
7F8W-CCKB-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
7EZM-CCKA-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
7XOW-CCKB-Gastrin-Gq/&β;1/&γ;2
gq_class-agq_amine
gq_peptide
gq_histamine7DFL-H1-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
gq_muscarinic6OIJ-M1-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
gq_peptidegq_cck
gq_angiotensin
gq_bombesin
gq_bradykinin
gs_5ht7XT8-5-HT4-Serotonin-Gs/&β;1/&γ;2
7XTB-5-HT6-Serotonin-Gs/&β;1/&γ;2
8JLZ-5-HT6-ST1936-Gs/&β;1/&γ;2
7XTC-5-HT7-5-CT-Gs/&β;1/&γ;2
6WHA-5-HT2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7RAN-5-HT2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8DPF-5-HT2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8DPG-5-HT2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
gs_adenosine8HDP-A2B-Adenosine-Gs/&β;1/&γ;2
8HDO-A2B-BAY 60-6583-Gs/&β;1/&γ;2
6GDG-A2A-NECA-Gs/&β;1/&γ;1
7XY7-A2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
7XY6-A2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
gs_adgr7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
gs_adrenergic3SN6-β2-BI167107-Gs/&β;1/&γ;2
7DHR-β2-Isoprenaline-Gs/&β;1/&γ;2
7DHI-β2-Salbutamol-Gs/&β;1/&γ;2
7XJH-β3-Isoproterenol-Gs/&β;1/&γ;2
7DH5-β3-Mirabegron-Gs/&β;1/&γ;2
7XJI-β3-Solabegron-Gs/&β;1/&γ;2
8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7JJO-β1-Isoprenaline-Gs/&β;1/&γ;2
8DCR-β1-Dobutamine-Gs/&β;1/&γ;2
7BZ2-β2-Arformoterol-Gs/&β;1/&γ;2
gs_aminegs_5ht
gs_adrenergic
gs_dopamine
gs_histamine
gs_muscarinic
gs_tar
gs_bileacid7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
7CFM-GPBA-P395-Gs/&β;1/&γ;2
7XTQ-GPBA-R399-Gs/&β;1/&γ;2
gs_bombesin8H0Q-BB2-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8H0P-BB1-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_bradykinin7F2O-BK2-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7EIB-BK1-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_calcitonings_ct
gs_cgrp
gs_cck7MBX-CCKA-Cholecystokinin-8-Gs/&β;1/&γ;1
7XOV-CCKA-SR146131-Gs/&β;1/&γ;2
gs_cgrp6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
gs_class-ags_amine
gs_nucleotide
gs_lipid
gs_peptide
gs_protein
gs_steroid
gs_class-bgs_class-b1
gs_class-b2
gs_class-b1gs_glucagon
gs_vip-pacap
gs_pth
gs_calcitonin
gs_crf
gs_class-b2gs_adgr
gs_class-tgs_taste
gs_compl-peptide8I9A-C3aB-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_crf6P9X-CRF1-Corticoliberin-Gs/&β;1/&γ;2
gs_ct7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
7TYL-CT-Amylin-Gs/&β;1/&γ;2
8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
gs_dopamine7F0T-D1-Dopamine-Gs/&β;1/&γ;2
7CKX-D1-A77636-Gs/&β;1/&γ;2
7JVQ-D1-Apomorphine-Gs/&β;1/&γ;2
7CKY-D1-PW0464-Gs/&β;1/&γ;2
8IRV-D5-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
7JV5-D1-SKF81297-Gs/&β;1/&γ;2
7JVP-D1-SKF83959-Gs/&β;1/&γ;2
7X2D-D1-Tavapadon-Gs/&β;1/&γ;2
7JOZ-D1-VFP-Gs/&β;1/&γ;2
gs_endothelin8HCQ-ETA-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8HCX-ETB-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
gs_ffa8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8GD9-EP4-Rivenprost-Gs/&β;1/&γ;2
8GDA-EP4-L902688-Gs/&β;1/&γ;2
8GDB-EP4-PGE2-Gs/&β;1/&γ;2
gs_galanin7WQ4-GAL2-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7XJL-GAL2-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
gs_ghrelin7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_glucagon6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
7DTY-GIP-GIP-Gs/&β;1/&γ;2
7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
gs_gphr7T9I-TSH-TSH-Gs/&β;1/&γ;2
7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
gs_histamine7YFC-H4-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7YFD-H4-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_lipidgs_ffa
gs_prostanoid
gs_melanocortin7F4D-MC1-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
7F4H-MC1-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
7F54-MC4-Afamelanotide-Gs/&β;1/&γ;2
7F53-MC4-Alpha-MSH-Gs/&β;1/&γ;2
7F55-MC4-Bremelanotide-Gs/&β;1/&γ;2
7PIV-MC4-Setmelanotide-Gs/&β;1/&γ;2
7F4I-MC1-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
7F58-MC4-THIQ-Gs/&β;1/&γ;2
gs_motilin8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_muscarinic8E9W-M3-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8E9Z-M3-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
gs_neuromedin7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_nucleotidegs_adenosine
gs_orexin7L1U-OX2-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7L1V-OX2-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7SR8-OX2-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
gs_peptidegs_cck
gs_motilin
gs_neuromedin
gs_orexin
gs_sst
gs_tachykinin
gs_trh
gs_vasopressin-ot
gs_bombesin
gs_bradykinin
gs_compl-peptide
gs_endothelin
gs_galanin
gs_ghrelin
gs_melanocortin
gs_prostanoid8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7CX2-EP2-PGE2-Gs/&β;1/&γ;2
7CX3-EP2-Taprenepag-Gs/&β;1/&γ;2
7D7M-EP4-Dinoprostone-Gs/&β;1/&γ;1
7CX4-EP2-Evatanepag-Gs/&β;1/&γ;2
8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_proteings_gphr
gs_pth8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
7F16-PTH2-TIP39-Gs/&β;1/&γ;2
7VVM-PTH1-PTH-Gs/&β;1/&γ;2
8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
gs_sst7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
gs_steroidgs_bileacid
gs_tachykinin8U26-NK1-Protachykinin-1-Gs/&β;1/&γ;2
7XWO-NK2-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7P00-NK1-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
gs_tar8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
8JLN-TA1-T1AM-Gs/&β;1/&γ;2
8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
gs_taste7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
gs_trh7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
gs_vasopressin-ot7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7DW9-V2-AVP-chim(NtGi1-Gs)/&β;1/&γ;2
gs_vip-pacap8E3Y-VPAC1-PACAP27-Gs/&β;1/&γ;2
7VQX-VPAC1-PACAP27-Gs/&β;1/&γ;2
8E3Z-VPAC1-VIP-Gs/&β;1/&γ;2
6M1I-PAC1-PACAP-Gs/&β;1/&γ;2
6VN7-VPAC1-PACAP-Gs/&β;1/&γ;2
gt_class-agt_opsin
gt_opsingt_sensory
gt_sensory6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
h1_off3RZE-H1-Cidoxepin
8X5Y-H1-Astemizole
8X63-H1-Mepyramine
8X64-H1-Desloratadine
h1_on7DFL-H1-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
h3_on_allo7F61-H3-PF-03654746-Cholesterol
h4_on7YFC-H4-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7YFD-H4-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
hca2_on8H2G-HCA2-Niacin-Gi1/&β;1/&γ;2
8IHI-HCA2-Acifran-Gi1/&β;1/&γ;2
8IHH-HCA2-LUF6283-Gi1/&β;1/&γ;2
8IHF-HCA2-MK6892-Gi1/&β;1/&γ;2
8JHY-HCA2-Compound 9n-Gi1/&β;1/&γ;2
8IHB-HCA2-GSK256073-Gi1/&β;1/&γ;2
8JIM-HCA2-MMF-Gi1/&β;1/&γ;2
8IJB-HCA2-Acipimox-Gi1/&β;1/&γ;2
8IJD-HCA2-MK6892-Gi1/&β;1/&γ;2
8J6J-HCA2-GSK256073-Gi1/&β;1/&γ;2
hca2_on_allo8J6P-HCA2-Niacin-Compound 9n-Gi1/&β;1/&γ;2
8J6Q-HCA2-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
hca3_on8IHJ-HCA3-Acifran-Gi1/&β;1/&γ;2
hca_onhca2_on
hca3_on
hcar_offsuccinate_off
hcar_onhca_on
histamine_offh1_off
histamine_onh1_on
h4_on
kop_off4DJH-κ-JDTic
kop_on8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
8DZP-κ-momSalB-Gi1/&β;1/&γ;2
8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
leuko_offblt_off
cyslt_off
leuko_onblt_on
lh_on7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
lh_on_allo7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
lipid_offcannabinoid_off
leuko_off
lpl_off
paf_off
prostanoid_off
lipid_oncannabinoid_on
ffa_on
gpr119_on
leuko_on
lpl_on
prostanoid_on
lpa1_off4Z36-LPA1-ONO-3080573
4Z34-LPA1-ONO-9780307
4Z35-LPA1-ONO-9910539
7YU4-LPA1-ONO-0740556
lpa1_on7TD0-LPA1-LPA-Gi1/&β;1/&γ;2
7YU3-LPA1-ONO-0740556-Gi1/&β;1/&γ;2
lpa_offlpa1_off
lpa_onlpa1_on
lpl_offs1p_off
lpa_off
lpl_ons1p_on
lpa_on
m1_off5CXV-M1-Tiotropium
m1_off_allo6WJC-M1-Atropine-Muscarinic toxin 7
m1_on6OIJ-M1-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
m2_off5ZKB-M2-AF-DX 384
5ZKC-M2-N-Methyl Scopolamine
5ZK3-M2-Quinuclidinyl benzilate hydrobromide
m2_on7T8X-M2-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
m2_on_allo7T94-M2-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
6OIK-M2-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
m3_off4U15-M3-Tiotropium
4U16-M3-N-Methyl Scopolamine
5ZHP-M3-PubChem 134828589
m3_on8E9Z-M3-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8E9W-M3-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
m4_off5DSG-M4-Tiotropium
m4_on7TRS-M4-Acetylcholine-Gi1/&β;1/&γ;2
7TRK-M4-Iperoxo-Gi1/&β;1/&γ;2
8E9X-M4-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
7V6A-M4-PubChem 9864275-Gi1/&β;1/&γ;2
m4_on_allo7TRP-M4-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
7TRQ-M4-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
7V68-M4-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
m5_off6OL9-M5-Tiotropium
mc1_on7F4H-MC1-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
7F4D-MC1-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
7F4I-MC1-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
mc2_on8GY7-MC2-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
mc3_on8IOC-MC3-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
mc4_on7F53-MC4-Alpha-MSH-Gs/&β;1/&γ;2
7F55-MC4-Bremelanotide-Gs/&β;1/&γ;2
7PIV-MC4-Setmelanotide-Gs/&β;1/&γ;2
7F58-MC4-THIQ-Gs/&β;1/&γ;2
7F54-MC4-Afamelanotide-Gs/&β;1/&γ;2
mc5_on8INR-MC5-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
8IOD-MC5-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
melanocortin_onmc2_on
mc1_on
mc3_on
mc4_on
mc5_on
melatonin_onmt1_on
mt2_on
mglu2_off7MTQ-mGlu2; mGlu2-LY341495
mglu2_on7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
mglu3_off7WI8-mGlu3; mGlu3-LY341495
7WIH-mGlu3; mGlu3-LY2794193
mglu4_on7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
mglu5_off7FD9-mGlu5; mGlu5-LY341495
mglu_offmglu2_off
mglu3_off
mglu5_off
mglu_onmglu2_on
mglu4_on
mop_off7UL4-μ-Alvimopan
4DKL-μ-Beta-funaltrexamine
8QOT-μ-Nanobody E
mop_on8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
8EF6-μ-Morphine-Gi1/&β;1/&γ;2
8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
8EFO-μ-PZM21-Gi1/&β;1/&γ;2
8EFL-μ-SR17018-Gi1/&β;1/&γ;2
motilin_on8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
mt1_on7VGY-MT1-2-Iodomelatonin-Gi1/&β;1/&γ;2
7DB6-MT1-Ramelteon-Gi1/&β;1/&γ;2
mt2_on7VH0-MT2-Ramelteon-Gi1/&β;1/&γ;1
muscarinic_offm2_off
m3_off
m4_off
m5_off
m1_off
muscarinic_onm2_on
m3_on
m4_on
m1_on
nk1_off6J20-NK1-Aprepitant
6HLL-NK1-CP99994
6E59-NK1-L-760735
nk1_on8U26-NK1-Protachykinin-1-Gs/&β;1/&γ;2
7P00-NK1-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
nk2_on7XWO-NK2-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
nmur1_on7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
nmur2_on7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
nmur_onnmur1_on
nmur2_on
nop_off4EA3-NOP-PubChem 10296561
5DHG-NOP-PubChem 25001412
5DHH-NOP-SB-612111
nop_on8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
npy1_off5ZBH-Y1-BMS-193885
5ZBQ-Y1-UR-MK-299
npy1_on7X9A-Y1-Neuropeptide Y-Gi1/&β;1/&γ;2
npy2_off7DDZ-Y2-JNJ-31020028
npy2_on7YOO-Y2-Neuropeptide Y-Gi1/&β;1/&γ;2
7YON-Y2-Peptide YY(3-36)-Gi1/&β;1/&γ;2
npy4_on7X9C-Y4-Pancreatic Hormone-Gi1/&β;1/&γ;2
npy_offnpy2_off
npy1_off
npy_onnpy2_on
npy4_on
npy1_on
nts1_off6Z4Q-NTS1-SR142948A
6Z4S-NTS1-SR48692
nts1_off_allo7UL2-NTS1-SR48692-Na
nts1_on6OS9-NTS1-JMV449-Gi1/&β;1/&γ;2
nts1_on_allo8JPB-NTS1-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
nts_offnts1_off
nts_onnts1_on
nucleotide_offadenosine_off
p2y_off
nucleotide_onadenosine_on
opioid_offkop_off
mop_off
nop_off
dop_off
opioid_onkop_on
mop_on
nop_on
dop_on
opsin_off1U19-Rhodopsin-11-cis-Retinal
2PED-Rhodopsin-9-cis-Retinal
5TE5-Rhodopsin-20-Methanoretinal
opsin_on6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
orexin_offox2_off
ox1_off
orexin_onox2_on
ot_off6TPK-OT-Retosiban
ot_on7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
ox1_off6TOT-OX1-Lemborexant
6TP4-OX1-ACT-462206
6TP6-OX1-Filorexant
6V9S-OX1-GTPL11403
6TP3-OX1-Nemorexant
6TQ6-OX1-PubChem 145714283
6TQ7-OX1-SB-334867
6TQ9-OX1-SB-408124
4ZJC-OX1-SB-674042
4ZJ8-OX1-Suvorexant
ox1_off_allo6TOD-OX1-EMPA-Na
6TOS-OX1-GSK1059865-Na
6TQ4-OX1-PubChem 16046844-Na
6TO7-OX1-Suvorexant-Na
ox2_off6TPN-OX2-HTL6641
7XRR-OX2-Lemborexant
ox2_on7L1V-OX2-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7L1U-OX2-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7SR8-OX2-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
p2y12_off4NTJ-P2Y12-AZD1283
7PP1-P2Y12-Selatogrel
p2y1_off4XNW-P2Y1-MRS2500
p2y_offp2y1_off
p2y12_off
paf_off5ZKQ-PAF-ABT-491
5ZKP-PAF-Foropafant (SR27417)
pca1_on6M1I-PAC1-PACAP-Gs/&β;1/&γ;2
peptide_offopioid_off
angiotensin_off
bombesin_off
cck_off
endothelin_off
ghrelin_off
npy_off
nts_off
orexin_off
vasopressin-ot_off
tachykinin_off
sst_off
peptide_onopioid_on
angiotensin_on
bombesin_on
cck_on
endothelin_on
ghrelin_on
npy_on
nts_on
orexin_on
vasopressin-ot_on
tachykinin_on
sst_on
relaxin_on
trh_on
nmur_on
motilin_on
melanocortin_on
galanin_on
fpr-alx_on
compl-peptide_on
bradykinin_on
apelin_on
prostanoid_offep_off
tp_off
dp_off
prostanoid_onep_on
fpa_on
protein_offccr_off
chemokine_off
gnrh_off
protein_onccr_on
chemokine_on
gphr_on
chemerin_on
pth1_on8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
7VVM-PTH1-PTH-Gs/&β;1/&γ;2
pth2_on7F16-PTH2-TIP39-Gs/&β;1/&γ;2
pth_onpth1_on
pth2_on
relaxin_onrxfp4_on
rxfp4_on7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
s1p1_off3V2Y-S1P1-PubChem 51892645
s1p1_on7TD3-S1P1-S1P-Gi1/&β;1/&γ;2
7TD4-S1P1-Siponimod-Gi1/&β;1/&γ;2
7VIF-S1P1-(S)-FTY720-P-Gi1/&β;1/&γ;2
7EO4-S1P1-BAF312-Gi1/&β;1/&γ;2
7VIG-S1P1-CBP-307-Gi1/&β;1/&γ;2
7EVZ-S1P1-Cenerimod-Gi1/&β;1/&γ;2
7EW0-S1P1-Ozanimod-Gi1/&β;1/&γ;2
7EW7-S1P1-PubChem 4077460-Gi1/&β;1/&γ;2
s1p2_on7T6B-S1P2-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
s1p3_on7EW3-S1P3-S1P-Gi1/&β;1/&γ;2
7EW4-S1P3-CYM5541-Gi1/&β;1/&γ;2
7EW2-S1P3-Fingolimod-Gi1/&β;1/&γ;2
s1p5_on7EW1-S1P5-Siponimod-Gi1/&β;1/&γ;2
s1p_offs1p1_off
s1p_ons1p3_on
s1p5_on
s1p1_on
s1p2_on
secretin_on6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
sensory_offopsin_off
sensory_onopsin_on
smo_off5L7I-SMO-Vismodegib
4O9R-SMO-Cyclopamine
4QIM-SMO-PubChem 24905375
4JKV-SMO-Taladegib (LY2940680)
smo_off_allo6D32-SMO-Cyclopamine-Cyclopamine
smo_on_allo6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
sst2_off7XNA-SST2-CYN154806
sst2_on7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
sst4_on7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
sst_offsst2_off
sst_onsst2_on
sst4_on
ste2_off7QA8-STE2-Peptide
ste2_on7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
steroid_onbileacid_on
succinate_off6RNK-Succinate-NF-56-EJ40
6Z10-Succinate-PubChem 154585554
ta1_on8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
8JLN-TA1-T1AM-Gs/&β;1/&γ;2
8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
tachykinin_offnk1_off
tachykinin_onnk1_on
nk2_on
tar_onta1_on
taste2_on7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
tp_off6IIV-TP-Daltroban
6IIU-TP-Ramatroban
trh_on7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
tsh_on7T9I-TSH-TSH-Gs/&β;1/&γ;2
tsh_on_allo7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
v2_on7DW9-V2-AVP-chim(NtGi1-Gs)/&β;1/&γ;2
vasopressin-ot_offot_off
vasopressin-ot_onot_on
v2_on
vip-pacap_onvpac1_on
vpac2_on
pca1_on
vpac1_on8E3Y-VPAC1-PACAP27-Gs/&β;1/&γ;2
8E3Z-VPAC1-VIP-Gs/&β;1/&γ;2
6VN7-VPAC1-PACAP-Gs/&β;1/&γ;2
vpac2_on7VQX-VPAC1-PACAP27-Gs/&β;1/&γ;2