psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.29	G.HN.33	3.26724	No	No	0	2	4
2	G.HN.36	b.b5x2	5.25598	No	Yes	0	4	7
3	G.HN.40	G.HN.44	4.30597	No	No	6	7	6
4	G.HN.40	b.b5x2	8.73995	No	Yes	0	7	7
5	G.HN.40	b.b5x3	4.28852	No	Yes	6	7	9
6	G.HN.43	b.b5x3	6.01981	No	Yes	0	9	9
7	G.HN.44	b.b5x3	9.02487	No	Yes	6	6	9
8	G.HN.46	G.HN.50	3.61794	No	No	0	4	5
9	G.HN.47	b.b4x2	3.44845	No	No	0	5	8
10	G.HN.50	b.b4x2	6.03423	No	No	0	5	8
11	G.HN.51	G.hns1.02	3.76849	No	No	0	4	4
12	G.HN.51	b.l1x4	5.60689	No	No	0	4	6
13	G.S1.03	G.hns1.01	10.1931	No	No	0	9	4
14	G.hns1.01	b.l1x4	3.61949	No	No	0	4	6
15	G.S1.01	G.S3.02	3.25724	No	No	0	7	4
16	G.S1.01	G.S3.04	3.53895	No	Yes	0	7	7
17	G.S1.02	G.S3.03	6.2288	No	Yes	0	6	8
18	G.S1.02	G.h2s4.05	6.22676	No	No	0	6	8
19	G.S1.02	I2x51	4.31073	No	Yes	0	6	6
20	G.S1.03	G.S3.06	4.08073	No	Yes	0	9	7
21	G.S1.04	G.S3.03	4.24416	No	Yes	0	7	8
22	G.S1.04	G.S4.03	4.06306	No	No	0	7	7
23	G.S1.05	G.S1.07	4.02893	No	No	0	9	8
24	G.S1.05	G.h2s4.01	16.2429	No	Yes	0	9	9
25	G.S1.05	G.S4.02	5.71321	No	No	0	9	8
26	G.H1.01	G.S1.06	5.27326	No	Yes	18	9	8
27	G.S1.06	G.S3.05	6.46601	Yes	No	0	8	8
28	G.S1.07	G.S4.04	3.25884	No	Yes	0	8	9
29	G.H3.01	G.s1h1.04	7.00114	Yes	Yes	19	9	9
30	G.S4.05	G.s1h1.05	3.55514	No	No	0	7	9
31	G.H1.01	G.S3.07	7.40193	No	No	18	9	9
32	G.H1.04	G.S4.05	2.9421	No	No	8	7	7
33	G.H1.04	G.S5.07	3.27003	No	Yes	8	7	9
34	G.hfs2.07	b.l7x4	3.6275	No	No	0	8	9
35	G.S2.01	b.l5x5	3.51019	No	Yes	0	9	9
36	G.S2.03	G.S3.06	6.30731	No	Yes	17	9	7
37	G.S2.04	G.S3.05	3.26338	No	No	0	7	8
38	G.S2.05	G.S3.04	12.5652	No	Yes	0	4	7
39	G.S2.06	G.S3.03	12.2298	Yes	Yes	0	9	8
40	G.S2.07	G.S3.02	8.68937	No	No	0	3	4
41	G.S2.08	G.s2s3.01	3.06532	No	No	7	6	5
42	G.H5.05	G.S2.08	3.80393	Yes	No	7	5	6
43	G.H5.08	G.S2.08	8.26645	Yes	No	7	8	6
44	G.H5.05	G.s2s3.01	8.07502	Yes	No	7	5	5
45	G.H5.08	G.s2s3.01	7.47724	Yes	No	7	8	5
46	G.S3.01	G.S3.03	4.51126	No	Yes	7	5	8
47	G.H5.08	G.S3.01	2.96673	Yes	No	7	8	5
48	G.S3.01	I2x51	4.11922	No	Yes	7	5	6
49	G.H5.08	G.S3.03	3.12967	Yes	Yes	7	8	8
50	G.H5.11	G.S3.03	4.5668	No	Yes	0	8	8
51	G.S3.04	G.S3.06	9.40282	Yes	Yes	17	7	7
52	G.S3.06	b.l5x5	16.6379	Yes	Yes	0	7	9
53	G.H2.07	G.S3.08	10.2571	Yes	No	0	9	9
54	G.H2.07	G.s3h2.03	3.85709	Yes	No	1	9	9
55	G.s3h2.03	b.l7x4	3.61389	No	No	0	9	9
56	G.s3h2.03	b.l9x6	4.20107	No	Yes	1	9	8
57	G.H2.01	G.H2.03	6.07162	No	No	0	9	9
58	G.H2.01	b.l13x6	4.76716	No	Yes	0	9	9
59	G.H2.03	G.H2.05	5.39777	No	No	0	9	8
60	G.H2.04	G.H2.07	5.87247	No	Yes	0	9	9
61	G.H2.04	G.H3.08	4.71566	No	No	0	9	8
62	G.H2.05	b.l17x6	7.2287	No	Yes	0	8	9
63	G.H2.06	b.l9x6	3.3453	Yes	Yes	1	9	8
64	G.H2.06	b.b14x1	7.95182	Yes	No	1	9	8
65	G.H2.06	b.l15x1	4.07681	Yes	Yes	1	9	7
66	G.H2.06	b.l17x6	7.23087	Yes	Yes	1	9	9
67	G.H2.06	b.b18x1	4.21739	Yes	No	0	9	9
68	G.H2.07	G.h2s4.01	3.22911	Yes	Yes	0	9	9
69	G.H2.07	b.l9x6	4.053	Yes	Yes	1	9	8
70	G.H2.08	G.H3.18	4.00549	No	No	0	9	9
71	G.H2.09	G.H3.17	9.02397	No	Yes	3	8	5
72	G.H2.09	b.l25x6	3.70368	No	Yes	3	8	8
73	G.H2.10	b.l3x1	3.41627	No	Yes	3	8	9
74	G.h2s4.01	G.h2s4.04	3.95922	Yes	No	0	9	9
75	G.h2s4.01	b.l5x5	11.2892	Yes	Yes	0	9	9
76	G.h2s4.02	G.h2s4.03	3.48355	No	No	3	8	6
77	G.h2s4.02	b.l1x6	6.44114	No	Yes	3	8	9
78	G.h2s4.02	b.l28x1	6.9486	No	Yes	3	8	9
79	G.h2s4.03	b.l1x6	6.18502	No	Yes	3	6	9
80	G.S4.02	G.h3s5.03	4.5985	No	No	0	8	7
81	G.H5.07	G.S4.03	3.35711	No	No	0	9	7
82	G.S4.04	G.S4.06	3.23438	Yes	No	0	9	7
83	G.H3.08	G.S4.04	4.92549	No	Yes	0	8	9
84	G.H3.09	G.S4.04	4.62023	Yes	Yes	0	9	9
85	G.S4.04	G.S5.04	2.95049	Yes	Yes	0	9	9
86	G.S4.05	G.S5.07	3.9955	No	Yes	8	7	9
87	G.H4.15	G.S4.06	6.01611	Yes	No	0	8	7
88	G.S4.07	G.s4h3.03	3.17697	No	No	0	8	8
89	G.S4.07	G.s5hg.01	9.98912	No	No	0	8	9
90	G.S5.06	G.s4h3.01	2.97002	No	No	0	8	6
91	G.HG.04	G.s4h3.01	3.82413	No	No	0	8	6
92	G.HG.03	G.s4h3.02	4.56955	Yes	No	0	6	9
93	G.H3.01	G.s4h3.03	5.30921	Yes	No	0	9	8
94	G.HG.07	G.s4h3.04	7.63059	No	Yes	0	9	8
95	G.HG.15	G.s4h3.04	7.22763	No	Yes	0	7	8
96	G.H3.01	G.H3.04	6.69478	Yes	No	0	9	9
97	G.H3.02	G.hgh4.02	5.01555	No	No	0	8	8
98	G.H3.02	G.H4.11	3.37545	No	No	0	8	8
99	G.H3.03	G.H3.06	4.32976	No	Yes	0	4	6
100	G.H3.03	G.H3.07	6.33194	No	No	0	4	5
101	G.H3.06	G.H4.14	4.04909	Yes	No	0	6	5
102	G.H3.06	G.H4.15	8.36935	Yes	Yes	0	6	8
103	G.H3.06	G.h4s6.01	3.06537	Yes	No	0	6	4
104	G.H3.09	G.H3.13	4.82706	Yes	Yes	20	9	6
105	G.H3.09	G.S5.02	4.08806	Yes	No	20	9	6
106	G.H3.09	G.H4.15	6.6024	Yes	Yes	0	9	8
107	G.H3.09	G.h4s6.01	5.46595	Yes	No	0	9	4
108	G.H3.09	G.S6.01	3.08983	Yes	No	0	9	5
109	G.H3.10	G.H3.14	3.65757	No	No	0	5	8
110	G.H3.10	G.h4s6.01	5.63319	No	No	0	5	4
111	G.H3.13	G.S5.02	4.50064	Yes	No	20	6	6
112	G.H3.13	G.h4s6.02	6.8593	Yes	No	0	6	7
113	G.H3.13	G.h4s6.08	3.03874	Yes	No	0	6	5
114	G.H3.13	G.h4s6.13	24.9202	Yes	No	0	6	7
115	G.H3.15	G.H3.18	9.06509	No	No	0	8	9
116	G.H3.16	G.H3.17	10.5532	No	Yes	0	5	5
117	G.H3.16	G.h3s5.01	3.66004	No	No	0	5	3
118	G.H3.17	b.l23x1	4.41759	Yes	Yes	3	5	6
119	G.H3.17	b.l25x6	12.4015	Yes	Yes	3	5	8
120	G.H3.17	b.l28x1	4.56951	Yes	Yes	3	5	9
121	G.h3s5.02	G.h4s6.12	3.58621	No	Yes	0	4	2
122	G.H5.14	G.S5.01	8.52022	No	No	0	6	8
123	G.S5.03	G.S5.05	3.18759	No	Yes	0	9	9
124	G.H5.10	G.S5.03	9.52958	No	No	0	7	9
125	G.S5.04	G.S5.06	3.3076	Yes	No	0	9	8
126	G.H4.15	G.S5.04	6.98671	Yes	Yes	0	8	9
127	G.S5.04	G.S6.01	3.15795	Yes	No	0	9	5
128	G.S5.05	G.S6.04	4.00873	Yes	No	0	9	9
129	G.S5.05	G.s6h5.01	6.67023	Yes	No	8	9	9
130	G.H5.03	G.S5.05	4.53681	Yes	Yes	8	9	9
131	G.H5.07	G.S5.05	3.57391	No	Yes	0	9	9
132	G.S5.06	G.S6.05	6.44082	No	Yes	0	8	5
133	G.S5.07	G.s5hg.01	4.52637	Yes	No	0	9	9
134	G.S5.07	G.s6h5.01	4.97909	Yes	No	8	9	9
135	G.HG.03	G.s5hg.01	5.98004	Yes	No	0	6	9
136	G.H4.07	G.HG.01	7.1136	Yes	No	9	5	6
137	G.HG.01	G.S6.05	9.3577	No	Yes	9	6	5
138	G.HG.02	G.HG.03	3.63622	No	Yes	0	9	6
139	G.H4.03	G.HG.08	3.23559	Yes	No	0	4	7
140	G.HG.09	G.hgh4.21	3.91316	No	Yes	0	2	4
141	G.HG.14	G.HG.17	4.20158	No	No	0	6	3
142	G.HG.15	G.hgh4.05	9.05058	No	Yes	0	7	6
143	G.HG.16	G.hgh4.05	5.24991	No	Yes	0	4	6
144	G.HG.17	G.hgh4.01	4.70687	No	Yes	0	3	6
145	G.H4.10	G.hgh4.02	5.65914	Yes	No	0	7	8
146	G.hgh4.03	G.hgh4.04	2.93564	No	Yes	0	6	6
147	G.H4.05	G.hgh4.05	12.0844	No	Yes	14	5	6
148	G.H4.10	G.hgh4.05	14.1215	Yes	Yes	14	7	6
149	G.hgh4.08	G.hgh4.11	3.31295	Yes	Yes	0	6	5
150	G.H4.05	G.hgh4.08	3.68195	No	Yes	14	5	6
151	G.H4.10	G.hgh4.08	8.35125	Yes	Yes	14	7	6
152	G.H4.13	G.hgh4.08	6.12276	Yes	Yes	0	3	6
153	G.hgh4.10	G.hgh4.11	3.11884	No	Yes	0	1	5
154	G.H4.08	G.hgh4.11	3.05306	Yes	Yes	0	3	5
155	G.H4.08	G.hgh4.14	4.12889	Yes	No	0	3	3
156	G.H4.04	G.hgh4.16	3.93165	No	No	0	4	1
157	G.hgh4.17	G.hgh4.20	6.02356	No	No	0	4	3
158	G.H4.04	G.hgh4.20	4.26163	No	No	0	4	3
159	G.H4.07	G.hgh4.20	5.14091	Yes	No	0	5	3
160	G.H4.01	G.hgh4.21	5.66888	No	Yes	0	1	4
161	G.H4.02	G.hgh4.21	7.21345	No	Yes	0	5	4
162	G.H4.04	G.H4.08	3.12393	No	Yes	0	4	3
163	G.H4.07	G.S6.05	12.3595	Yes	Yes	9	5	5
164	G.H4.08	G.H4.12	5.64613	Yes	Yes	0	3	4
165	G.H4.10	G.H4.14	7.4234	Yes	No	0	7	5
166	G.H4.12	G.H4.16	3.02261	Yes	No	9	4	4
167	G.H4.12	G.S6.03	6.49606	Yes	No	9	4	5
168	G.H4.12	G.S6.05	7.85875	Yes	Yes	9	4	5
169	G.H4.13	G.H4.17	4.40361	Yes	No	0	3	4
170	G.H4.14	G.H4.17	3.99758	No	No	0	5	4
171	G.H4.16	G.S6.03	3.65279	No	No	9	4	5
172	G.S6.01	G.h4s6.02	4.16855	No	No	0	5	7
173	G.h4s6.10	G.h4s6.12	4.82847	No	Yes	0	3	2
174	G.S6.02	G.h4s6.20	6.51161	Yes	Yes	10	8	4
175	G.H5.17	G.h4s6.20	6.62525	Yes	Yes	10	5	4
176	5x72	G.h4s6.20	4.10699	No	Yes	10	6	4
177	G.H5.10	G.S6.02	12.2038	No	Yes	0	7	8
178	G.H5.13	G.S6.02	5.94479	Yes	Yes	10	8	8
179	G.H5.14	G.S6.02	7.18454	No	Yes	0	6	8
180	G.H5.17	G.S6.02	5.82092	Yes	Yes	10	5	8
181	G.H5.06	G.S6.04	12.4197	No	No	0	4	9
182	G.H5.10	G.S6.04	9.78674	No	No	0	7	9
183	G.H5.03	G.s6h5.01	6.84244	Yes	No	8	9	9
184	G.H5.02	G.s6h5.05	4.04233	No	No	0	4	9
185	G.H5.03	G.s6h5.05	4.30193	Yes	No	8	9	9
186	G.H5.06	G.s6h5.05	3.93801	No	No	8	4	9
187	G.H5.01	G.H5.02	3.42897	No	No	0	9	4
188	G.H5.03	G.H5.06	3.56573	Yes	No	8	9	4
189	G.H5.05	G.H5.08	3.48331	Yes	Yes	7	5	8
190	G.H5.05	G.H5.09	4.49231	Yes	No	0	5	4
191	G.H5.08	I2x51	4.08067	Yes	Yes	7	8	6
192	G.H5.12	I2x50	3.63635	No	No	0	7	8
193	G.H5.12	I2x51	3.41327	No	Yes	7	7	6
194	G.H5.13	G.H5.17	4.52965	Yes	Yes	10	8	5
195	5x68	G.H5.13	5.18813	No	Yes	10	7	8
196	G.H5.15	G.H5.19	3.13027	No	Yes	0	8	8
197	G.H5.15	I2x50	3.78308	No	No	0	8	8
198	G.H5.16	I2x50	3.91181	No	No	0	6	8
199	5x68	G.H5.16	4.42805	No	No	0	7	6
200	5x68	G.H5.17	6.96073	No	Yes	10	7	5
201	5x72	G.H5.17	4.01565	No	Yes	10	6	5
202	3x53	G.H5.19	3.27157	No	Yes	4	8	8
203	G.H5.19	I2x53	3.19493	Yes	Yes	4	8	7
204	G.H5.20	G.H5.25	3.74155	Yes	No	0	8	8
205	G.H5.20	G.H5.26	4.27025	Yes	No	0	8	8
206	3x54	G.H5.20	4.24581	No	Yes	0	9	8
207	5x65	G.H5.20	3.15681	No	Yes	0	8	8
208	G.H5.22	G.H5.23	6.06563	No	Yes	0	4	4
209	2x39	G.H5.23	3.17422	No	Yes	0	8	4
210	3x50	G.H5.23	13.3503	Yes	Yes	0	9	4
211	6x32	G.H5.24	3.75814	No	No	0	8	6
212	b.1x7	g.h1x8	3.36708	No	Yes	0	8	7
213	b.1x11	g.h1x11	4.86197	No	No	0	8	9
214	b.1x13	b.1x16	3.99377	No	Yes	0	1	4
215	b.1x15	b.1x19	3.58306	No	No	0	7	6
216	b.1x19	b.b21x1	8.23876	No	Yes	0	6	7
217	b.1x19	b.b21x2	3.80243	No	No	0	6	6
218	b.b21x2	b.lh12x1	3.39015	No	No	0	6	3
219	b.lh12x2	g.l1x6	9.36963	No	No	0	8	4
220	b.lh12x2	g.h2x2	6.13876	No	No	0	8	9
221	b.h2x3	b.lh12x4	7.17861	No	No	0	1	3
222	b.b21x4	b.h2x1	4.25789	No	No	0	5	5
223	b.b21x5	b.h2x1	5.66525	Yes	No	0	4	5
224	b.h2x5	b.l24x2	4.10894	No	No	0	5	6
225	b.l22x5	b.lhb1x3	3.15009	Yes	Yes	0	9	2
226	b.l24x3	b.lhb1x3	3.56042	Yes	Yes	0	5	2
227	b.lhb1x4	b.lhb1x5	3.22576	No	No	0	1	1
228	b.l22x5	b.lhb1x6	5.09318	Yes	No	21	9	3
229	b.b24x7	b.lhb1x6	6.96609	No	No	21	9	3
230	b.lhb1x10	b.lhb1x8	3.52673	No	No	0	4	2
231	b.b25x7	b.lhb1x11	4.82206	No	No	0	7	4
232	b.lhb1x11	g.ctx5	3.87808	No	No	0	4	9
233	b.b1x1	b.b1x3	3.75712	No	Yes	0	5	7
234	b.b1x2	b.b28x4	5.87625	No	Yes	11	3	6
235	b.b1x2	b.b28x6	8.73419	No	Yes	11	3	9
236	b.b1x3	b.b28x7	7.05177	Yes	No	0	7	9
237	b.b1x3	g.ctx17	3.30295	Yes	No	0	7	7
238	b.b1x4	b.b5x1	3.9212	No	No	0	7	5
239	b.b1x4	b.b28x5	3.38536	No	No	13	7	5
240	b.b1x4	g.ctx16	5.20765	No	Yes	13	7	8
241	b.b1x5	b.l1x1	8.33313	No	No	0	3	7
242	b.b1x5	b.b28x4	7.47372	No	Yes	0	3	6
243	b.b1x6	b.b4x6	17.7452	No	Yes	0	9	9
244	b.b1x6	b.b28x3	6.29749	No	Yes	0	9	7
245	b.b28x2	b.l1x1	6.66969	No	No	0	4	7
246	b.l1x3	b.l1x7	9.45225	Yes	No	0	9	9
247	b.b3x4	b.l1x3	7.99389	No	Yes	6	9	9
248	b.b3x6	b.l1x3	12.2034	No	Yes	6	9	9
249	b.l1x3	b.l3x2	3.22265	Yes	Yes	6	9	9
250	b.b4x4	b.l1x3	11.6269	No	Yes	6	8	9
251	b.b4x6	b.l1x3	3.78362	Yes	Yes	6	9	9
252	b.l1x4	b.l3x2	7.6183	No	Yes	0	6	9
253	b.l1x5	b.l3x2	3.14046	No	Yes	0	7	9
254	b.l1x6	b.l3x1	6.92818	Yes	Yes	3	9	9
255	b.l1x6	b.l28x1	20.5089	Yes	Yes	3	9	9
256	b.b28x3	b.l1x7	3.05917	Yes	No	0	7	9
257	b.b2x1	b.b6x1	3.4469	Yes	No	0	8	9
258	b.b2x1	b.l28x1	6.11133	Yes	Yes	3	8	9
259	b.b2x3	b.b2x5	3.04325	No	Yes	0	6	7
260	b.b26x2	b.b2x3	5.04341	No	No	0	7	6
261	b.b2x4	b.b6x5	3.11746	No	Yes	0	6	6
262	b.b10x4	b.b2x4	12.9759	No	No	0	6	6
263	b.b2x5	b.b3x2	8.00902	Yes	No	0	7	5
264	b.b2x5	b.l4x1	5.19539	Yes	No	0	7	5
265	b.b2x5	b.l27x1	10.7175	Yes	No	0	7	8
266	b.b27x2	b.b2x5	4.26527	No	Yes	0	5	7
267	b.b6x5	b.l2x1	4.31594	Yes	No	0	6	5
268	b.l2x3	b.l2x5	3.40484	No	No	0	8	5
269	b.b3x1	b.l2x3	5.59626	No	No	0	5	8
270	b.l27x1	b.l2x4	6.23773	No	No	22	8	5
271	b.l27x3	b.l2x4	9.10208	No	No	22	7	5
272	b.b4x7	b.l2x5	14.4891	No	No	0	8	5
273	b.l2x5	b.l4x2	23.2477	No	No	0	5	4
274	b.b3x1	b.b6x5	4.09975	No	Yes	0	5	6
275	b.b3x2	b.b4x6	4.84567	No	Yes	0	5	9
276	b.b3x3	b.b4x3	3.45033	Yes	Yes	0	8	7
277	b.b3x3	b.b4x5	3.26699	Yes	No	0	8	7
278	b.b3x3	b.b6x3	3.67261	Yes	No	0	8	8
279	b.b3x3	b.b6x5	4.76559	Yes	Yes	0	8	6
280	b.b3x4	b.b4x6	5.82717	No	Yes	6	9	9
281	b.b28x3	b.b3x4	3.79304	Yes	No	0	7	9
282	b.b3x5	b.b6x3	2.99258	No	No	0	9	8
283	b.b3x6	b.l3x2	7.94727	No	Yes	6	9	9
284	b.l3x1	b.l5x5	6.98449	Yes	Yes	0	9	9
285	b.b4x2	b.l3x2	6.19036	No	Yes	0	8	9
286	b.b4x1	b.l5x1	3.02093	No	Yes	0	8	8
287	b.b4x3	b.b5x7	4.23411	Yes	Yes	0	7	7
288	b.b4x3	b.l5x1	4.24526	Yes	Yes	15	7	8
289	b.b4x3	b.b7x4	3.32361	Yes	No	15	7	8
290	b.b4x4	b.b4x6	13.5913	No	Yes	6	8	9
291	b.b4x4	b.b5x3	3.83104	No	Yes	6	8	9
292	b.b4x5	b.b5x5	6.75232	No	Yes	0	7	5
293	b.b4x5	b.l8x1	3.35927	No	No	0	7	5
294	b.b4x6	b.b5x3	9.79824	Yes	Yes	6	9	9
295	b.b4x7	b.l4x3	8.11246	No	No	0	8	6
296	b.l4x1	g.ctx16	4.46375	No	Yes	0	5	8
297	b.l4x2	g.ctx15	10.6933	No	Yes	13	4	9
298	b.l4x2	g.ctx16	6.01613	No	Yes	13	4	8
299	b.b5x2	b.l4x3	9.0997	Yes	No	0	7	6
300	b.b5x4	b.b5x5	5.8948	No	Yes	0	5	5
301	b.b5x5	b.l8x8	5.00945	Yes	No	0	5	4
302	b.b5x7	b.b5x8	3.35852	Yes	No	0	7	5
303	b.b5x7	b.b8x4	5.95284	Yes	Yes	0	7	6
304	b.b5x7	b.l8x8	6.52876	Yes	No	0	7	4
305	b.l5x1	b.l5x6	3.99215	Yes	No	0	8	9
306	b.b7x4	b.l5x1	3.40485	No	Yes	15	8	8
307	b.b8x4	b.l5x1	5.28746	Yes	Yes	15	6	8
308	b.b9x3	b.l5x2	4.84317	Yes	No	0	6	6
309	b.l5x3	b.l7x3	8.59018	No	No	0	8	9
310	b.l5x4	b.l5x5	3.44076	No	Yes	0	8	9
311	b.l5x5	b.l7x2	5.54495	Yes	No	0	9	9
312	b.b6x1	b.l7x1	3.28169	No	No	0	9	9
313	b.b6x1	b.l9x6	5.70162	No	Yes	0	9	8
314	b.b10x3	b.b6x2	5.1141	No	No	0	8	8
315	b.b6x5	b.l6x4	4.24476	Yes	No	0	6	5
316	b.b6x5	b.b7x2	3.11194	Yes	No	0	6	8
317	b.b10x5	b.l6x1	5.7488	Yes	No	0	9	6
318	b.l6x3	b.l6x5	7.23961	No	Yes	16	6	4
319	b.l10x3	b.l6x3	9.01323	No	No	16	6	6
320	b.b7x1	b.l6x5	3.64216	Yes	Yes	16	4	4
321	b.l6x5	b.l8x2	7.19191	Yes	No	0	4	4
322	b.l10x3	b.l6x5	4.28789	No	Yes	16	6	4
323	b.b7x1	b.b8x3	3.48053	Yes	No	0	4	6
324	b.b7x1	b.b8x5	11.4213	Yes	No	0	4	4
325	b.b7x1	b.l10x3	7.36796	Yes	No	16	4	6
326	b.b7x2	b.l8x1	4.99551	No	No	0	8	5
327	b.b10x5	b.b7x3	3.38521	Yes	No	0	9	9
328	b.b7x4	b.b8x4	4.38466	No	Yes	15	8	6
329	b.l7x3	b.l7x5	4.81004	No	No	0	9	6
330	b.l7x4	b.l9x5	3.69128	No	No	0	9	8
331	b.b9x3	b.l7x5	4.66806	Yes	No	0	6	6
332	b.b8x1	b.b9x4	4.17903	No	No	0	8	9
333	b.b8x2	b.b8x4	5.70986	No	Yes	0	8	6
334	b.b8x2	b.b9x3	3.62356	No	Yes	0	8	6
335	b.b10x5	b.b8x3	3.00021	Yes	No	0	9	6
336	b.b8x4	b.l8x10	6.19797	Yes	No	0	6	4
337	b.b8x5	b.l8x3	4.64312	No	No	0	4	3
338	b.l8x5	b.l8x7	3.50402	Yes	No	0	3	3
339	b.l8x5	b.l8x9	3.27387	Yes	No	0	3	3
340	b.b12x6	b.b9x4	17.0257	Yes	No	0	8	9
341	b.l9x3	b.l9x7	3.89512	Yes	No	1	9	7
342	b.b11x4	b.l9x3	6.2541	No	Yes	1	9	9
343	b.b11x6	b.l9x3	13.8007	No	Yes	1	9	9
344	b.l11x2	b.l9x3	6.35893	Yes	Yes	1	9	9
345	b.b12x6	b.l9x3	5.59399	Yes	Yes	1	8	9
346	b.l11x2	b.l9x4	6.40665	Yes	No	0	9	5
347	b.l11x1	b.l9x6	5.98652	No	Yes	1	9	8
348	b.l13x6	b.l9x6	7.95471	Yes	Yes	1	9	8
349	b.b14x1	b.l9x6	3.16146	No	Yes	1	8	8
350	b.b11x4	b.l9x7	3.48606	No	No	1	9	7
351	b.b10x2	b.b10x4	4.19879	No	No	0	6	6
352	b.b10x2	b.b14x3	4.13789	No	Yes	0	6	5
353	b.b10x4	b.b14x5	3.21726	No	No	0	6	5
354	b.b10x5	b.b11x2	8.58737	Yes	No	0	9	7
355	b.b11x1	b.l10x1	5.81964	No	No	0	5	3
356	b.b14x5	b.l10x1	4.31932	No	No	0	5	3
357	b.b12x7	b.l10x4	6.36513	No	No	0	9	3
358	b.l10x4	b.l12x2	7.32826	No	No	0	3	6
359	b.b11x1	b.b12x5	4.64236	No	No	0	5	6
360	b.b11x2	b.b12x6	3.00286	No	Yes	0	7	8
361	b.b11x2	b.l12x1	3.73239	No	No	0	7	6
362	b.b11x3	b.b14x3	3.57669	No	Yes	5	5	5
363	b.b11x3	b.b15x1	3.66978	No	Yes	5	5	9
364	b.b11x4	b.b12x6	9.17098	No	Yes	1	9	8
365	b.b11x5	b.l13x7	5.62489	No	No	0	6	9
366	b.b11x5	b.b14x3	4.14978	No	Yes	0	6	5
367	b.b11x6	b.l11x1	3.24891	No	No	1	9	9
368	b.b11x6	b.l11x2	8.33863	No	Yes	1	9	9
369	b.l11x1	b.l13x6	3.69791	No	Yes	1	9	9
370	b.b12x2	b.l11x2	9.14176	No	Yes	0	7	9
371	b.b12x2	b.l13x1	3.62798	No	No	0	7	2
372	b.b12x3	b.b13x7	3.79066	No	Yes	0	8	7
373	b.b12x3	b.l13x7	3.39187	No	No	0	8	9
374	b.b12x3	b.b15x3	2.98032	No	No	0	8	9
375	b.b12x4	b.b12x6	4.28937	No	Yes	1	4	8
376	b.b12x4	b.b13x3	5.17277	No	No	1	4	4
377	b.b12x5	b.b13x4	3.54499	No	No	5	6	4
378	b.b12x5	b.b13x5	3.93487	No	No	5	6	4
379	b.b12x6	b.b13x3	13.7237	Yes	No	1	8	4
380	b.b12x7	b.l12x3	8.71998	No	No	0	9	5
381	b.b13x2	b.l12x3	4.8756	No	No	0	4	5
382	b.b13x3	b.b13x6	5.456	No	No	0	4	4
383	b.b13x4	b.b13x5	3.4423	No	No	5	4	4
384	b.b13x5	b.b13x7	4.85957	No	Yes	5	4	7
385	b.b13x7	b.b15x1	9.53835	Yes	Yes	5	7	9
386	b.b13x7	b.b16x6	14.598	Yes	Yes	5	7	8
387	b.b13x7	b.b17x1	3.64771	Yes	No	0	7	4
388	b.l13x3	b.l13x7	6.35598	Yes	No	0	9	9
389	b.b15x3	b.l13x3	5.77688	No	Yes	5	9	9
390	b.b15x5	b.l13x3	7.83576	No	Yes	5	8	9
391	b.l13x3	b.l15x2	5.98091	Yes	Yes	5	9	9
392	b.b16x4	b.l13x3	13.4697	Yes	Yes	5	6	9
393	b.b16x6	b.l13x3	3.98206	Yes	Yes	5	8	9
394	b.l13x4	b.l15x2	6.92932	No	Yes	0	3	9
395	b.l13x6	b.l15x1	3.81727	Yes	Yes	1	9	7
396	b.b14x1	b.l15x1	3.17625	No	Yes	1	8	7
397	b.b14x2	b.b18x3	4.19639	No	Yes	0	7	8
398	b.b14x3	b.b15x1	4.41805	Yes	Yes	5	5	9
399	b.b14x4	b.b18x5	5.73072	No	Yes	0	8	5
400	b.b18x5	b.l14x1	4.01859	Yes	No	0	5	4
401	b.l14x3	b.l14x5	10.4242	No	No	0	5	5
402	b.l14x5	b.l16x2	3.7159	No	No	0	5	9
403	b.b16x5	b.l14x6	4.91942	Yes	No	0	5	3
404	b.b16x7	b.l14x6	3.81318	No	No	0	9	3
405	b.b15x1	b.b16x6	11.2882	Yes	Yes	5	9	8
406	b.b15x2	b.b16x5	3.11012	Yes	Yes	0	6	5
407	b.b15x2	b.b18x3	6.17152	Yes	Yes	1	6	8
408	b.b15x2	b.b18x5	7.36576	Yes	Yes	0	6	5
409	b.b15x2	b.b19x2	7.62345	Yes	Yes	1	6	6
410	b.b15x3	b.b16x6	7.13219	No	Yes	5	9	8
411	b.b15x4	b.l17x7	3.19701	No	No	0	6	7
412	b.b15x5	b.l15x2	3.51825	No	Yes	5	8	9
413	b.l15x1	b.l17x6	9.67698	Yes	Yes	1	7	9
414	b.b16x2	b.l15x2	7.91637	No	Yes	0	5	9
415	b.b16x4	b.b16x6	8.62945	Yes	Yes	5	6	8
416	b.b16x4	b.b17x3	6.04816	Yes	No	5	6	5
417	b.b16x4	b.b17x6	11.437	Yes	No	0	6	7
418	b.b16x5	b.b17x5	4.98051	Yes	Yes	0	5	7
419	b.b16x5	b.l20x1	5.19153	Yes	No	0	5	6
420	b.b16x6	b.b17x3	5.45829	Yes	No	5	8	5
421	b.b16x7	b.l16x3	8.75311	No	No	23	9	3
422	b.b16x7	b.b17x4	9.44771	No	No	23	9	5
423	b.b17x2	b.l16x3	5.56582	No	No	0	3	3
424	b.b17x4	b.l16x3	4.84501	No	No	23	5	3
425	b.b17x3	g.h1x10	3.9567	No	No	0	5	9
426	b.b17x5	b.b17x7	7.3412	Yes	Yes	1	7	8
427	b.b17x5	b.b21x1	11.311	Yes	Yes	1	7	7
428	b.b17x5	g.l1x2	3.81921	Yes	No	0	7	2
429	b.b17x6	g.h1x14	5.85979	No	No	0	7	9
430	b.b17x7	b.b19x2	10.6212	Yes	Yes	1	8	6
431	b.b17x7	b.b20x6	8.85532	Yes	Yes	1	8	6
432	b.b17x7	b.b21x1	4.01892	Yes	Yes	1	8	7
433	b.l17x3	b.l17x7	7.23155	Yes	No	1	9	7
434	b.b19x4	b.l17x3	7.7184	Yes	Yes	1	8	9
435	b.b19x6	b.l17x3	11.982	No	Yes	1	9	9
436	b.l17x3	b.l19x2	5.0257	Yes	Yes	1	9	9
437	b.b20x4	b.l17x3	16.3704	Yes	Yes	1	8	9
438	b.l17x4	b.l19x2	6.57162	No	Yes	0	3	9
439	b.l17x5	b.l17x6	3.15531	No	Yes	1	6	9
440	b.l17x5	b.l19x1	4.45391	No	No	1	6	9
441	b.l17x6	b.l19x1	5.4922	Yes	No	1	9	9
442	b.b19x4	b.l17x7	4.30091	Yes	No	1	8	7
443	b.b18x1	b.l19x1	10.007	No	No	0	9	9
444	b.b18x3	b.b19x2	4.77017	Yes	Yes	1	8	6
445	b.b18x3	b.b19x4	4.46276	Yes	Yes	1	8	8
446	b.l18x1	b.l18x2	10.1919	Yes	Yes	12	6	7
447	b.l18x1	b.l18x3	6.82632	Yes	No	12	6	5
448	b.b22x5	b.l18x1	8.79611	Yes	Yes	12	7	6
449	b.l18x1	b.l22x4	3.94445	Yes	No	12	6	9
450	b.l18x1	g.h2x8	5.27268	Yes	No	0	6	7
451	b.l18x1	g.h2x11	3.89379	Yes	Yes	12	6	6
452	b.b22x5	b.l18x2	3.90647	Yes	Yes	12	7	7
453	b.l18x2	b.l22x4	3.38333	Yes	No	12	7	9
454	b.l18x2	g.h2x11	4.89659	Yes	Yes	12	7	6
455	b.l18x3	b.l18x5	7.87704	No	No	0	5	2
456	b.l18x3	g.h2x11	9.64382	No	Yes	12	5	6
457	b.l18x5	b.l20x2	8.20394	No	Yes	0	2	9
458	b.b19x2	b.b20x6	10.7684	Yes	Yes	1	6	6
459	b.b19x3	b.b22x5	3.03735	No	Yes	0	4	7
460	b.b19x4	b.b20x6	6.00532	Yes	Yes	1	8	6
461	b.b19x5	b.l21x9	4.43657	No	No	0	5	6
462	b.b19x6	b.l19x2	6.84498	No	Yes	1	9	9
463	b.b20x2	b.l19x2	9.03871	No	Yes	0	6	9
464	b.b20x2	b.b20x4	6.36538	No	Yes	0	6	8
465	b.b20x2	b.l21x1	4.24411	No	No	0	6	2
466	b.b20x3	b.b21x7	3.886	No	Yes	0	8	5
467	b.b20x3	b.l21x9	4.9663	No	No	0	8	6
468	b.b20x4	b.b20x6	4.02191	Yes	Yes	1	8	6
469	b.b20x4	b.b21x3	15.1363	Yes	No	1	8	6
470	b.b20x4	b.b21x6	9.17642	Yes	No	1	8	1
471	b.b20x5	b.b21x4	3.87583	No	No	0	7	5
472	b.b20x5	b.b21x7	5.41078	No	Yes	0	7	5
473	b.b20x6	b.b21x3	6.67781	Yes	No	1	6	6
474	b.b20x7	b.l20x2	3.07904	Yes	Yes	0	9	9
475	b.b20x7	b.l20x3	3.86625	Yes	No	0	9	7
476	b.b20x7	b.b21x4	6.51326	Yes	No	0	9	5
477	b.b20x7	g.h2x4	4.15926	Yes	No	0	9	7
478	b.l20x2	g.l1x5	7.50853	Yes	No	0	9	4
479	b.l20x2	g.h2x7	6.6854	Yes	No	0	9	5
480	b.b21x1	g.l1x4	9.30736	Yes	Yes	0	7	8
481	b.b21x2	g.h2x1	4.41315	No	No	0	6	8
482	b.b21x3	b.b21x6	3.99823	No	No	1	6	1
483	b.b21x5	b.b21x7	7.82647	Yes	Yes	0	4	5
484	b.b21x5	b.b25x1	3.09668	Yes	No	0	4	2
485	b.b21x7	b.b23x2	4.45218	Yes	No	0	5	6
486	b.b21x7	b.b24x6	9.06722	Yes	Yes	0	5	8
487	b.l21x2	b.l21x4	8.76426	Yes	No	0	4	4
488	b.l21x2	b.l21x5	3.42391	Yes	No	0	4	4
489	b.b25x3	b.l21x2	7.33443	No	Yes	0	5	4
490	b.b23x6	b.l21x5	5.50326	Yes	No	0	7	4
491	b.b23x6	b.l21x7	3.0435	Yes	Yes	3	7	5
492	b.l21x7	b.l23x1	3.86769	Yes	Yes	3	5	6
493	b.l21x7	b.l23x2	7.03618	Yes	No	3	5	8
494	b.b23x6	b.l21x9	8.90366	Yes	No	0	7	6
495	b.b22x1	b.l23x1	4.01348	No	Yes	3	8	6
496	b.b22x1	b.l25x6	6.52735	No	Yes	3	8	8
497	b.b22x2	b.b26x3	5.03498	No	Yes	0	8	6
498	b.b22x4	b.b26x3	3.22375	No	Yes	0	5	6
499	b.b22x4	b.b26x5	4.08246	No	No	0	5	7
500	b.b22x5	b.b23x2	8.37121	Yes	No	0	7	6
501	b.b23x1	b.l22x1	3.61241	No	No	0	5	9
502	b.l22x1	g.ctx3	6.87708	No	Yes	0	9	9
503	b.l22x3	g.ctx3	8.28294	No	Yes	0	9	9
504	b.b24x7	b.l22x5	12.4884	No	Yes	21	9	9
505	b.l22x5	b.l24x2	7.38919	Yes	No	0	9	6
506	b.l22x5	g.ctx6	3.04777	Yes	Yes	0	9	6
507	b.b23x1	b.b24x5	4.8911	No	No	0	5	5
508	b.b23x3	b.b24x5	4.02758	No	No	0	7	5
509	b.b23x3	b.b26x3	3.11018	No	Yes	0	7	6
510	b.b23x3	b.b27x1	4.2455	No	No	0	7	6
511	b.b23x4	b.b23x6	4.18702	No	Yes	0	6	7
512	b.b23x6	b.l23x2	3.73992	Yes	No	3	7	8
513	b.b23x6	b.b24x4	11.6361	Yes	Yes	3	7	6
514	b.b23x6	b.b24x6	6.7958	Yes	Yes	3	7	8
515	b.l23x1	b.l25x6	13.5614	Yes	Yes	3	6	8
516	b.b24x2	b.l23x2	6.66163	No	No	0	5	8
517	b.b24x2	b.b25x6	3.71775	No	No	0	5	3
518	b.b24x3	b.b25x7	4.90794	No	No	0	5	7
519	b.b24x3	b.l25x7	3.21874	No	No	0	5	7
520	b.b24x4	b.b24x6	4.77444	Yes	Yes	3	6	8
521	b.b24x4	b.b25x3	10.9774	Yes	No	3	6	5
522	b.b24x4	b.b25x6	3.55233	Yes	No	0	6	3
523	b.b24x6	b.b25x3	6.86973	Yes	No	3	8	5
524	b.b24x7	b.l24x3	7.51841	No	Yes	0	9	5
525	b.l24x2	g.h2x12	4.3128	No	No	0	6	7
526	b.b25x2	b.l24x3	4.32276	No	Yes	0	2	5
527	b.b25x7	b.b28x6	14.7973	No	Yes	0	7	9
528	b.l25x3	b.l25x7	3.13838	Yes	No	0	9	7
529	b.b27x3	b.l25x3	6.20609	No	Yes	0	8	9
530	b.b27x5	b.l25x3	13.4628	No	Yes	11	9	9
531	b.l25x3	b.l28x2	6.79272	Yes	Yes	11	9	9
532	b.b28x4	b.l25x3	9.70977	Yes	Yes	11	6	9
533	b.l25x4	b.l28x2	6.12929	No	Yes	0	5	9
534	I1x49	b.l25x4	3.24564	No	No	0	7	5
535	b.l25x5	b.l28x1	5.62575	No	Yes	0	7	9
536	b.l25x6	b.l28x1	20.2383	Yes	Yes	3	8	9
537	b.b26x1	b.l28x1	5.26723	No	Yes	0	9	9
538	b.b26x3	b.b27x3	3.88846	Yes	No	0	6	8
539	b.b26x5	b.b27x1	3.77861	No	No	0	7	6
540	b.l27x1	b.l27x3	6.46716	No	No	22	8	7
541	b.l27x3	b.l27x5	7.02972	No	No	0	7	5
542	b.l27x5	g.ctx4	5.29807	No	No	0	5	7
543	b.l27x5	g.ctx15	5.14335	No	Yes	0	5	9
544	b.l27x6	g.ctx16	4.49609	No	Yes	0	7	8
545	b.b27x3	b.b28x6	7.65814	No	Yes	0	8	9
546	b.b27x5	b.l28x2	7.31034	No	Yes	11	9	9
547	b.b28x2	b.l28x2	10.203	No	Yes	0	4	9
548	b.b28x4	b.b28x6	6.72053	Yes	Yes	11	6	9
549	b.b28x5	g.ctx16	4.15722	No	Yes	13	5	8
550	b.b28x7	g.ctx14	9.59993	No	No	0	9	9
551	g.h1x10	g.h1x14	5.88729	No	No	0	9	9
552	g.l1x2	g.l1x4	5.79583	No	Yes	0	2	8
553	g.h2x3	g.l1x5	4.47326	No	No	0	5	4
554	g.h2x3	g.h2x7	5.32883	No	No	0	5	5
555	g.h2x11	g.h2x15	16.244	Yes	No	0	6	6
556	g.ctx3	g.ctx4	3.67739	Yes	No	0	9	7
557	g.ctx3	g.ctx6	6.20806	Yes	Yes	0	9	6
558	g.ctx10	g.ctx9	3.50998	No	No	24	5	6
559	g.ctx13	g.ctx9	3.80945	No	No	24	5	6
560	g.ctx14	g.ctx9	3.56557	No	No	0	9	6
561	g.ctx10	g.ctx13	5.78153	No	No	24	5	5
562	g.ctx14	g.ctx15	4.51081	No	Yes	0	9	9
563	g.ctx15	g.ctx16	4.26198	Yes	Yes	13	9	8
564	1x39	2x61	4.771	No	No	0	6	6
565	1x39	7x39	8.43339	No	Yes	0	6	6
566	1x43	2x57	5.10173	No	Yes	0	6	7
567	1x46	7x47	5.81452	No	No	0	8	6
568	1x50	2x50	7.81889	No	Yes	0	9	9
569	1x50	2x51	3.69257	No	No	0	9	7
570	1x50	7x50	6.56455	No	No	0	9	9
571	1x53	2x47	3.51394	No	No	0	9	9
572	1x56	8x54	3.30043	No	Yes	0	8	7
573	1x57	2x44	8.29062	Yes	No	0	7	6
574	1x60	I1x49	4.39289	Yes	No	0	6	7
575	1x60	I1x50	4.63735	Yes	No	0	6	8
576	1x60	8x53	4.27122	Yes	No	0	6	7
577	2x40	I1x50	3.20466	No	No	25	9	8
578	2x37	2x40	4.80096	No	No	0	5	9
579	2x39	3x49	4.34591	No	Yes	0	8	8
580	2x40	8x50	5.41471	No	Yes	25	9	8
581	2x42	3x46	2.98733	Yes	Yes	4	8	9
582	2x42	3x49	5.92167	Yes	Yes	4	8	8
583	2x42	4x45	3.17958	Yes	No	4	8	5
584	2x45	3x42	7.59271	No	No	0	9	8
585	2x45	4x46	7.81961	No	No	0	9	7
586	2x45	4x50	4.65755	No	No	0	9	9
587	2x46	2x50	3.6089	Yes	Yes	4	9	9
588	2x46	3x42	4.20697	Yes	No	0	9	8
589	2x46	3x43	3.85943	Yes	No	4	9	8
590	2x46	7x49	5.72998	Yes	Yes	4	9	9
591	2x49	4x50	3.77166	No	No	0	8	9
592	2x50	3x39	4.30182	Yes	No	0	9	9
593	2x50	7x46	8.07796	Yes	No	0	9	9
594	2x50	7x49	6.25191	Yes	Yes	4	9	9
595	2x52	3x35	3.86359	No	No	0	7	7
596	2x53	2x56	3.10404	No	Yes	0	8	7
597	2x53	3x35	4.45254	No	No	0	8	7
598	2x53	7x46	5.23133	No	No	0	8	9
599	2x56	3x28	3.41774	Yes	Yes	0	7	5
600	2x56	3x32	8.00363	Yes	No	2	7	7
601	2x56	7x42	4.26723	Yes	Yes	2	7	7
602	2x57	7x39	2.95742	Yes	Yes	2	7	6
603	2x57	7x42	5.47387	Yes	Yes	2	7	7
604	2x59	3x28	6.66767	No	Yes	0	6	5
605	2x60	2x64	4.14667	No	No	0	6	4
606	2x60	3x28	4.8014	No	Yes	0	6	5
607	2x63	E1x50	3.48406	No	Yes	0	4	7
608	2x64	7x35	4.2821	No	No	0	4	3
609	2x66	E1x49	3.5504	No	No	0	4	5
610	E1x50	E1x52	9.36983	Yes	Yes	0	7	6
611	3x25	E1x50	6.22819	No	Yes	26	9	7
612	3x28	E1x50	4.66673	Yes	Yes	0	5	7
613	E1x50	E2x50	5.77747	Yes	No	26	7	9
614	3x24	E1x52	3.94411	No	Yes	0	6	6
615	3x22	E2	3.61479	No	Yes	0	3	3
616	3x25	E2x50	6.60516	No	No	26	9	9
617	3x30	4x58	3.93836	No	No	0	6	4
618	3x32	7x42	9.43421	No	Yes	2	7	7
619	3x32	Lig	11.6539	No	Yes	2	7	0
620	3x33	4x57	7.29312	No	No	0	5	7
621	3x33	Lig	11.8734	No	Yes	0	5	0
622	3x34	4x57	2.9758	No	No	0	6	7
623	3x36	6x48	3.88094	No	Yes	2	7	8
624	3x36	Lig	8.04707	No	Yes	2	7	0
625	3x37	4x53	4.93612	No	No	0	6	8
626	3x37	5x461	4.01622	No	No	0	6	5
627	3x38	4x50	5.84805	No	No	0	8	9
628	3x40	5x50	3.20468	No	No	0	7	8
629	3x40	6x44	4.32164	No	Yes	2	7	9
630	3x40	6x48	6.78801	No	Yes	2	7	8
631	3x42	4x49	4.06649	No	No	0	8	7
632	3x43	7x49	5.26348	No	Yes	4	8	9
633	3x43	7x53	7.85644	No	Yes	4	8	9
634	3x44	5x50	3.21864	No	No	0	8	8
635	3x44	5x53	3.84382	No	No	0	8	6
636	3x46	3x50	3.15865	Yes	Yes	4	9	9
637	3x46	7x53	4.72875	Yes	Yes	4	9	9
638	3x47	5x54	4.28786	No	No	0	9	8
639	3x47	5x57	3.29571	No	No	0	9	7
640	3x47	5x58	4.37971	No	Yes	0	9	9
641	3x49	I2x53	7.58322	Yes	Yes	4	8	7
642	3x49	I2x57	4.01041	Yes	No	4	8	7
643	3x50	7x53	3.89019	Yes	Yes	4	9	9
644	3x51	3x55	10.6805	Yes	No	0	8	6
645	3x51	5x57	7.72549	Yes	No	0	8	7
646	3x51	5x60	8.07071	Yes	No	0	8	5
647	3x52	I2x53	3.97156	No	Yes	0	4	7
648	3x53	I2x53	7.12937	No	Yes	4	8	7
649	3x54	5x61	3.86035	No	No	0	9	9
650	I2x53	I2x57	7.1996	Yes	No	4	7	7
651	4x38	4x40	3.3783	No	No	0	8	4
652	4x60	5x39	3.33077	No	Yes	0	5	7
653	4x61	E2	4.12995	No	Yes	2	5	3
654	4x63	E2	3.43578	No	Yes	2	5	3
655	4x64	E2	5.33188	No	Yes	0	7	3
656	E2	E2	48.0505	Yes	Yes	2	3	3
657	E2	E2x52	8.50518	Yes	No	2	3	4
658	5x39	E2	5.91757	Yes	Yes	2	7	3
659	5x36	E2	3.73016	No	Yes	2	4	3
660	E2	E3	3.11186	Yes	Yes	2	3	3
661	E2	E2x51	9.91292	Yes	No	0	3	3
662	E2x52	Lig	3.82682	No	Yes	2	4	0
663	5x40	E2	4.83699	No	Yes	2	5	3
664	E2	Lig	3.06491	Yes	Yes	2	3	0
665	5x36	5x38	4.34821	No	No	0	4	3
666	5x36	5x39	4.25393	No	Yes	2	4	7
667	5x37	6x59	3.40806	No	No	0	4	4
668	5x37	6x60	5.26938	No	No	0	4	4
669	5x39	5x43	4.29649	Yes	No	0	7	5
670	5x43	Lig	3.57205	No	Yes	0	5	0
671	5x44	6x52	4.02099	No	Yes	0	6	7
672	5x44	6x56	3.23105	No	No	0	6	5
673	5x45	5x48	4.8623	No	No	0	5	5
674	5x461	Lig	3.16893	No	Yes	0	5	0
675	5x47	5x48	5.15035	Yes	No	0	8	5
676	5x47	5x51	4.86331	Yes	No	0	8	7
677	5x47	6x44	3.51176	Yes	Yes	2	8	9
678	5x47	6x48	3.40843	Yes	Yes	2	8	8
679	5x47	6x49	3.677	Yes	Yes	0	8	6
680	5x47	6x52	15.8212	Yes	Yes	2	8	7
681	5x49	5x50	3.51091	No	No	0	5	8
682	5x54	6x44	4.27127	No	Yes	0	8	9
683	5x58	6x37	4.75513	Yes	No	0	9	8
684	5x58	6x40	3.80086	Yes	No	0	9	8
685	5x58	6x41	3.91965	Yes	No	0	9	8
686	5x59	5x63	3.48965	No	No	0	3	3
687	5x62	5x66	6.48845	Yes	No	0	6	6
688	5x62	6x34	3.82151	Yes	No	0	6	8
689	5x66	6x30	3.88288	No	No	0	6	7
690	6x40	7x53	4.36634	No	Yes	0	8	9
691	6x44	6x48	5.85625	Yes	Yes	2	9	8
692	6x47	7x45	7.25446	No	No	0	8	9
693	6x48	6x52	4.20186	Yes	Yes	2	8	7
694	6x48	7x41	9.61122	Yes	No	2	8	7
695	6x48	7x45	8.32268	Yes	No	0	8	9
696	6x48	Lig	3.91619	Yes	Yes	2	8	0
697	6x50	7x37	3.03482	No	No	0	9	6
698	6x51	6x52	4.96576	Yes	Yes	2	6	7
699	6x51	7x34	4.20164	Yes	No	0	6	4
700	6x51	7x38	6.28484	Yes	No	2	6	5
701	6x51	Lig	9.67108	Yes	Yes	2	6	0
702	6x52	Lig	5.80089	Yes	Yes	2	7	0
703	6x54	7x37	3.20137	No	No	0	4	6
704	6x55	Lig	2.96054	No	Yes	2	5	0
705	6x58	E3	5.90954	No	Yes	0	3	3
706	6x61	E3	4.58677	No	Yes	0	4	3
707	7x30	7x33	2.99866	No	No	0	4	4
708	7x38	7x42	7.03473	No	Yes	2	5	7
709	7x38	Lig	7.95797	No	Yes	2	5	0
710	7x39	7x42	7.18264	Yes	Yes	2	6	7
711	7x42	Lig	4.13169	Yes	Yes	2	7	0
712	7x45	7x49	7.66426	No	Yes	0	9	9
713	7x52	7x53	3.71197	No	Yes	0	8	9
714	7x54	8x50	4.17644	No	Yes	0	7	8
715	8x47	8x49	5.0093	No	No	0	8	6
716	8x47	8x50	3.58271	No	Yes	0	8	8
717	G.S1.06	G.S3.07	4.67775	Yes	No	18	8	9
718	G.S2.03	G.S3.04	7.8137	No	Yes	17	9	7
719	G.h3s5.01	G.h4s6.12	2.93137	No	Yes	0	3	2
720	G.hgh4.05	G.hgh4.08	3.97277	Yes	Yes	14	6	6
721	G.H5.08	G.H5.12	3.53012	Yes	No	7	8	7
722	3x53	G.H5.23	3.10657	No	Yes	0	8	4
723	b.b1x1	b.lhb1x10	3.96883	No	No	0	5	4
724	b.b1x6	b.b28x5	3.04941	No	No	0	9	5
725	I1x48	b.l1x1	3.77157	No	No	0	6	7
726	b.b2x1	b.l3x1	10.3336	Yes	Yes	3	8	9
727	b.b8x3	b.l12x1	4.6784	No	No	0	6	6
728	b.l10x1	b.l14x4	3.58241	No	No	0	3	1
729	b.b11x1	b.l10x2	6.88031	No	No	0	5	5
730	b.l17x5	b.l19x2	4.20211	No	Yes	1	6	9
731	b.b27x1	g.ctx5	2.99881	No	No	0	6	9
732	g.ctx2	g.h2x15	4.26803	No	No	0	3	6
733	g.ctx12	g.ctx13	3.43002	No	No	0	6	5
734	8x50	I1x50	6.18412	Yes	No	25	8	8
735	2x42	3x45	5.58758	Yes	No	4	8	7
736	2x60	7x42	4.62871	No	Yes	0	6	7
737	3x30	4x61	3.39892	No	No	0	6	5
738	3x45	4x45	4.44028	No	No	4	7	5
739	3x48	3x52	3.70977	No	No	0	6	4
740	3x50	5x58	3.3903	Yes	Yes	0	9	9
741	3x56	I2x52	4.38986	No	No	0	7	4
742	5x41	6x56	3.21645	No	No	0	5	5
743	5x56	5x60	5.40108	No	No	0	4	5
744	E3	E3	3.5148	Yes	Yes	2	3	3
745	G.HN.30	G.HN.33	4.33926	No	No	0	4	4
746	G.S2.07	G.s2s3.02	3.8507	No	No	0	3	4
747	G.H2.10	b.b2x1	4.22519	No	Yes	3	8	8
748	G.hgh4.01	G.s4h3.15	6.48146	Yes	No	0	6	9
749	G.H3.14	G.h4s6.08	3.67452	No	No	0	8	5
750	b.b2x1	b.l1x6	4.96984	Yes	Yes	3	8	9
751	3x26	E2	4.77976	No	Yes	2	6	3
752	3x48	5x57	3.66115	No	No	0	6	7
753	6x51	6x55	4.83384	Yes	No	2	6	5
754	G.S4.07	G.s1h1.04	4.83627	No	Yes	0	8	9
755	G.H5.19	I2x54	3.63835	Yes	No	0	8	4
756	I1x48	I1x51	5.13008	No	No	0	6	8
757	2x59	E1x52	3.25293	No	Yes	0	6	6
758	3x55	3x56	3.47781	No	No	0	6	7
759	G.s1h1.03	G.s1h1.04	3.15624	No	Yes	19	8	9
760	G.hgh4.01	G.s4h3.04	3.80547	Yes	Yes	0	6	8
761	G.HG.14	G.HG.16	6.26733	No	No	0	6	4
762	1x52	8x54	4.82374	No	Yes	0	7	7
763	4x65	E2	4.28604	No	Yes	0	0	3
764	7x41	Lig	4.39837	No	Yes	2	7	0
765	G.H3.01	G.s1h1.03	3.15162	Yes	No	19	9	8
766	2x38	I2x57	4.0466	No	No	0	6	7
767	8x49	I1x49	2.96579	No	No	0	6	7
768	6x30	6x31	2.96169	No	No	0	7	5
769	7x55	8x54	3.01477	No	Yes	0	5	7
770	E1	E1x50	3.75833	No	Yes	0	0	7
771	G.H4.03	G.hgh4.21	2.92297	Yes	Yes	0	4	4
772	1x53	7x54	2.91558	No	No	0	9	7
773	b.b23x1	b.lhb1x9	2.9154	No	No	0	5	3
774	5x55	6x41	2.89983	No	No	0	5	8
775	b.b18x4	b.b22x5	2.89771	No	Yes	0	3	7
776	b.b18x2	b.b22x3	2.89764	No	No	0	5	6
777	b.l22x2	g.ctx3	2.88441	No	Yes	0	1	9
778	b.l14x2	b.l18x4	2.88224	No	No	0	4	7
779	2x43	3x46	2.88042	No	Yes	0	8	9
780	b.1x2	b.1x5	2.8711	No	No	0	1	3
781	b.1x2	b.1x6	2.86768	No	No	0	1	3
782	G.S1.06	G.S4.03	2.86748	Yes	No	0	8	7
783	b.b10x1	b.b11x5	2.86416	No	No	0	9	6
784	6x33	G.H5.25	2.8556	No	No	0	8	8
785	8x48	8x51	2.85389	No	No	0	5	8
786	b.h2x1	g.h2x5	2.84584	No	No	0	5	6
787	1x59	8x57	2.84513	No	No	0	6	7
788	2x66	E1x51	2.83922	No	No	0	4	3
789	G.hgh4.17	G.hgh4.18	2.79071	No	No	0	4	1
790	G.H3.05	G.S4.06	2.78951	No	No	0	9	7
791	b.h2x4	g.h2x5	2.78872	No	No	0	3	6
792	6x49	6x50	2.75671	Yes	No	0	6	9
793	3x29	E2x52	2.75561	No	No	0	4	4
794	4x59	4x60	2.73857	No	No	0	7	5
795	G.HN.37	b.b5x2	2.72813	No	Yes	0	3	7
796	3x54	5x64	2.72411	No	No	0	9	6
797	G.H2.07	G.H2.08	2.7223	Yes	No	0	9	9
798	b.1x1	b.1x5	2.72123	Yes	No	0	4	3
799	1x46	2x57	2.71274	No	Yes	0	8	7
800	b.b10x2	b.b6x2	2.70606	No	No	0	6	8
801	b.1x4	g.h1x4	2.70417	No	No	0	8	5
802	G.HG.07	G.s4h3.02	2.6965	No	No	0	9	9
803	2x42	4x42	2.6873	Yes	No	0	8	7
804	b.l14x1	b.l14x3	2.68319	No	No	0	4	5
805	2x551	3x31	2.6751	No	No	0	5	5
806	4x38	4x41	2.67301	No	No	0	8	6
807	G.H4.10	G.hgh4.04	2.66807	Yes	Yes	0	7	6
808	b.l21x8	b.l23x1	2.66351	No	Yes	0	4	6
809	6x49	6x53	2.64897	Yes	No	0	6	6
810	b.b12x7	b.b13x4	2.64851	No	No	0	9	4
811	G.H3.12	G.S1.07	2.63823	No	No	0	8	8
812	8x48	G.H5.24	2.63758	No	No	0	5	6
813	g.ctx1	g.ctx2	2.63608	No	No	0	1	3
814	b.b19x1	b.l18x1	2.63372	No	Yes	0	6	6
815	b.1x4	g.h1x5	2.63102	No	Yes	0	8	6
816	b.lhb1x3	g.h2x9	2.62094	Yes	No	0	2	4
817	G.S4.01	G.S5.03	2.61255	No	No	0	8	9
818	1x47	2x55	2.61121	No	No	0	7	5
819	G.H5.21	G.h4s6.12	2.60615	No	Yes	0	4	2
820	3x51	5x61	2.59967	Yes	No	0	8	9
821	b.b10x5	b.l6x2	2.59814	Yes	No	0	9	6
822	G.H2.01	b.b12x1	2.58288	No	No	0	9	6
823	1x37	1x41	2.57001	No	No	0	5	5
824	G.HG.02	G.s6h5.02	2.56863	No	No	0	9	8
825	b.b23x5	b.b24x3	2.56631	No	No	0	7	5
826	1x46	2x54	2.54951	No	No	0	8	7
827	b.1x11	g.h1x12	2.54634	No	Yes	0	8	6
828	b.b15x1	b.l16x1	2.54391	Yes	No	0	9	4
829	g.h1x5	g.h1x9	2.54145	Yes	No	0	6	6
830	1x47	2x51	2.50277	No	No	0	7	7
831	1x54	2x44	2.50094	No	No	0	8	6
832	G.HN.43	b.b5x6	2.49907	No	No	0	9	6
833	b.b26x4	b.b2x5	2.49705	No	Yes	0	5	7
834	b.b10x5	b.b6x4	2.47491	Yes	No	0	9	7
835	b.l27x2	b.l2x2	2.46209	No	No	0	5	1
836	b.b16x3	b.b19x2	2.45292	No	Yes	0	6	6
837	5x40	6x59	2.4503	No	No	0	5	4
838	G.H5.04	G.S2.06	2.43293	No	Yes	0	8	9
839	b.b27x4	b.b28x3	2.43258	No	Yes	0	5	7
840	b.b24x2	b.l25x1	2.41148	No	No	0	5	3
841	3x41	4x49	2.38133	No	No	0	5	7
842	G.HG.13	G.s4h3.04	2.37914	No	Yes	0	7	8
843	5x71	G.H5.13	2.37849	No	Yes	0	4	8
844	b.h2x2	b.lh12x4	2.3749	No	No	0	1	3
845	7x51	7x55	2.37387	No	No	0	7	5
846	1x57	8x50	2.36579	Yes	Yes	0	7	8
847	5x62	6x37	2.36569	Yes	No	0	6	8
848	g.ctx11	g.ctx17	2.35917	No	No	0	4	7
849	6x45	6x49	2.34811	No	Yes	0	6	6
850	b.l22x2	b.l27x4	2.34753	No	No	0	1	9
851	b.b21x5	b.h2x2	2.34295	Yes	No	0	4	1
852	g.h1x12	g.h1x8	2.33903	Yes	Yes	0	6	7
853	g.ctx7	g.ctx8	2.33554	No	No	0	4	8
854	G.H1.01	G.s1h1.01	2.33412	No	No	0	9	9
855	G.HN.52	G.hns1.03	2.33042	No	No	0	3	5
856	1x51	2x51	2.32654	No	No	0	4	7
857	6x36	7x56	2.32271	No	No	0	9	7
858	G.H1.09	G.S2.04	2.31741	No	No	0	8	7
859	4x56	4x57	2.31203	No	No	0	5	7
860	2x62	E1x52	2.3013	No	Yes	0	5	6
861	6x43	7x52	2.30085	No	No	0	5	8
862	b.b18x5	b.l18x4	2.29895	Yes	No	0	5	7
863	E1x51	E1x52	2.29783	No	Yes	0	3	6
864	G.H4.03	G.HG.05	2.29714	Yes	No	0	4	4
865	b.1x5	b.1x9	2.28764	No	No	0	3	4
866	3x27	3x31	2.28588	No	No	0	5	5
867	1x54	2x48	2.27991	No	No	0	8	6
868	g.h2x14	g.h2x15	2.26914	No	No	0	4	6
869	1x42	7x39	2.25701	No	Yes	0	7	6
870	b.l8x4	b.l8x5	2.23841	No	Yes	0	3	3
871	I2x52	I2x56	2.23708	No	No	0	4	5
872	b.b2x2	b.b6x3	2.23588	No	No	0	7	8
873	b.b22x3	b.b23x2	2.22559	No	No	0	6	6
874	b.b24x1	b.l25x5	2.22435	No	No	0	4	7
875	1x45	7x47	2.21103	No	No	0	5	6
876	b.l21x2	b.l21x3	2.20659	Yes	No	0	4	3
877	G.H1.08	G.S2.06	2.194	No	Yes	0	9	9
878	b.b13x1	b.b9x2	2.18833	No	No	0	4	5
879	b.1x18	g.l1x4	2.1779	No	Yes	0	4	8
880	G.hgh4.01	G.s4h3.05	2.16938	Yes	No	0	6	9
881	8x50	8x54	2.1636	Yes	Yes	0	8	7
882	b.1x3	g.h1x5	2.1475	No	Yes	0	1	6
883	b.b9x2	b.l12x1	2.14028	No	No	0	5	6
884	G.HN.48	G.HN.51	2.12814	No	No	0	4	4
885	b.b7x1	b.b9x1	2.12242	Yes	No	0	4	4
886	b.b7x5	b.l7x1	2.11	No	No	0	9	9
887	b.b5x3	b.l1x2	2.10202	Yes	No	0	9	9
888	3x34	4x54	2.08537	No	No	0	6	4
889	b.1x16	b.1x17	2.07438	Yes	No	0	4	2
890	b.l8x3	b.l8x5	2.07094	No	Yes	0	3	3
891	b.l7x5	b.l9x1	2.06767	No	No	0	6	5
892	b.b16x2	b.l17x1	2.067	No	No	0	5	2
893	b.1x13	b.1x9	2.05824	No	No	0	1	4
894	G.HG.12	G.HG.13	2.05256	No	No	0	3	7
895	g.h1x12	g.h1x9	2.04405	Yes	No	0	6	6
896	3x41	4x52	2.04119	No	No	0	5	4
897	G.H4.03	G.H4.07	2.03173	Yes	Yes	0	4	5
898	6x43	7x48	2.00228	No	No	0	5	6
899	G.HN.33	G.HN.37	1.99895	No	No	0	4	3
900	b.1x12	b.1x16	1.98939	No	Yes	0	6	4
901	6x32	G.H5.26	1.98012	No	No	0	8	8
902	G.hns1.03	I2x55	1.97928	No	No	0	5	5
903	G.h4s6.02	G.h4s6.03	1.97037	No	Yes	0	7	4
904	b.1x15	g.h1x15	1.96826	No	No	0	7	8
905	b.1x12	b.1x15	1.96398	No	No	0	6	7
906	2x41	4x39	1.95273	No	No	0	4	3
907	7x31	7x35	1.93356	No	No	0	2	3
908	b.b12x6	b.l9x2	1.92974	Yes	No	0	8	5
909	G.S2.02	G.hfs2.06	1.92296	No	No	0	5	7
910	1x57	2x41	1.92229	Yes	No	0	7	4
911	b.lhb1x2	b.lhb1x3	1.91724	No	Yes	0	1	2
912	7x30	E3	1.90205	No	Yes	2	4	3
913	G.HN.46	G.HN.49	1.90065	No	No	0	4	4
914	b.1x2	b.ntx2	1.89601	No	No	0	1	5
915	1x43	2x58	1.88896	No	No	0	6	8
916	b.l13x5	b.l15x2	1.88023	No	Yes	0	5	9
917	G.H1.07	G.s6h5.04	1.8769	Yes	No	0	9	9
918	b.b28x1	b.b28x2	1.87022	No	No	0	4	4
919	b.1x1	g.h1x1	1.86811	Yes	No	0	4	2
920	b.b24x5	b.b25x5	1.86594	No	No	0	5	4
921	g.h1x12	g.l1x1	1.86277	Yes	No	0	6	1
922	b.1x22	g.l1x4	1.85779	No	Yes	0	3	8
923	G.h4s6.11	G.h4s6.20	1.85042	No	Yes	0	2	4
924	b.b25x4	b.lhb1x9	1.84451	No	No	0	4	3
925	2x55	2x551	1.83724	No	No	0	5	5
926	1x48	1x49	1.83133	No	No	0	5	8
927	4x48	4x52	1.82217	No	No	0	4	4
928	g.h1x11	g.h1x7	1.81912	No	No	0	9	2
929	G.H1.05	G.S3.05	1.81411	No	No	0	7	8
930	g.ctx6	g.ctx7	1.81353	Yes	No	0	6	4
931	b.b17x2	g.h1x13	1.79733	No	No	0	3	1
932	b.b20x1	b.l21x5	1.79619	No	No	0	5	4
933	7x43	7x48	1.79246	No	No	0	5	6
934	G.HG.16	G.hgh4.06	1.78678	No	No	0	4	2
935	b.1x14	b.1x18	1.78377	No	No	0	4	4
936	b.1x6	g.h1x8	1.7825	No	Yes	0	3	7
937	G.H1.10	G.H1.11	1.77972	No	No	0	9	0
938	G.S2.02	G.S3.07	1.7682	No	No	0	5	9
939	1x36	2x65	1.75644	No	Yes	0	6	5
940	b.l24x3	b.lhb1x1	1.74828	Yes	No	0	5	1
941	b.l24x3	b.lhb1x5	1.74053	Yes	No	0	5	1
942	G.hns1.03	I2x56	1.73792	No	No	0	5	5
943	3x26	4x62	1.7298	No	No	0	6	4
944	1x57	1x58	1.70324	Yes	No	0	7	4
945	G.HN.29	G.HN.34	1.6997	No	No	0	2	4
946	1x59	1x60	1.69923	No	Yes	0	6	6
947	b.b28x6	b.l25x2	1.6952	Yes	No	0	9	5
948	b.l27x2	b.l2x4	1.69376	No	No	0	5	5
949	7x30	7x32	1.68677	No	No	0	4	1
950	G.h4s6.09	G.h4s6.13	1.68603	No	No	0	4	7
951	1x60	8x56	1.68023	Yes	No	0	6	4
952	b.b16x6	b.l13x2	1.67202	Yes	No	0	8	6
953	b.b21x7	b.l24x1	1.66059	Yes	No	0	5	5
954	G.H4.06	G.hgh4.05	1.63507	No	Yes	0	8	6
955	G.s1h1.05	G.s1h1.06	1.62446	No	No	0	9	9
956	6x36	G.H5.25	1.62369	No	No	0	9	8
957	4x56	5x46	1.61357	No	No	0	5	4
958	g.h2x13	g.h2x9	1.60935	No	No	0	1	4
959	G.HN.39	b.b5x5	1.58162	No	Yes	0	4	5
960	5x66	5x70	1.57732	No	No	0	6	4
961	5x76	G.h4s6.03	1.57714	No	Yes	0	3	4
962	b.1x10	b.1x6	1.57082	No	No	0	1	3
963	4x41	4x45	1.56021	No	No	0	6	5
964	1x48	1x52	1.54938	No	No	0	5	7
965	b.h2x3	b.lh12x3	1.52901	No	No	0	1	4
966	b.b20x6	b.l17x2	1.51109	Yes	No	0	6	6
967	1x29	1x32	1.51038	No	No	0	0	3
968	6x57	E3	1.50904	No	Yes	0	4	3
969	4x47	4x51	1.50035	No	No	0	3	4
970	G.S2.02	G.s3h2.01	1.49963	No	No	0	5	9
971	8x48	8x52	1.48021	No	No	0	5	5
972	b.ntx2	b.ntx3	1.45932	No	No	0	5	0
973	G.HN.52	I2x58	1.4175	No	No	0	3	0
974	G.hgh4.15	G.hgh4.16	1.40862	No	No	0	2	1
975	b.h2x4	g.h2x2	1.38398	No	No	0	3	9
976	1x55	1x59	1.38371	No	No	0	5	6
977	5x79	G.h4s6.03	1.3741	No	Yes	0	5	4
978	G.hgh4.11	G.hgh4.13	1.37114	Yes	No	0	5	4
979	G.hgh4.04	G.hgh4.07	1.34999	Yes	No	0	6	2
980	2x41	4x43	1.32741	No	No	0	4	2
981	G.H1.03	G.s1h1.06	1.31559	Yes	No	0	9	9
982	1x52	8x58	1.31066	No	No	0	7	6
983	6x35	6x39	1.30031	No	No	0	7	7
984	b.lhb1x6	b.lhb1x7	1.26926	No	No	0	3	1
985	G.HG.03	G.HG.06	1.23851	Yes	No	0	6	6
986	1x35	2x65	1.22398	No	Yes	0	5	5
987	G.s1h1.02	G.s1h1.05	1.21629	No	No	0	8	9
988	G.h4s6.03	I3	1.20693	Yes	No	0	4	0
989	b.b16x1	b.l17x3	1.2013	No	Yes	0	4	9
990	G.H1.07	G.H5.03	1.17963	Yes	Yes	0	9	9
991	G.HN.26	G.HN.30	1.16856	No	No	0	6	4
992	g.h1x3	g.h1x7	1.13874	No	No	0	3	2
993	G.H1.02	G.H1.03	1.12812	No	Yes	0	9	9
994	G.HN.37	G.HN.41	1.11482	No	No	0	3	4
995	5x69	6x29	1.10719	No	No	0	5	6
996	1x44	1x48	1.10247	No	No	0	5	5
997	4x68	E2	1.10083	No	Yes	2	0	3
998	b.1x16	b.1x20	1.09355	Yes	No	0	4	2
999	A:A:V57	G.S2.06	1.0925	No	Yes	0	0	9
1000	7x36	7x40	1.06183	No	No	0	5	7
1001	5x67	5x71	1.06089	No	No	0	4	4
1002	G.H2.02	G.H2.03	1.05543	No	No	0	8	9
1003	5x69	G.H5.26	1.05437	No	No	0	5	8
1004	5x75	G.H4.16	1.02866	No	No	0	1	4
1005	G.HN.49	G.HN.53	1.02019	No	No	0	4	2
1006	G.H5.15	G.H5.18	1.01952	No	No	0	8	3
1007	2x64	2x65	1.01812	No	Yes	0	4	5
1008	1x32	2x65	1.01423	No	Yes	0	3	5
1009	b.1x8	g.h1x8	0.987908	No	Yes	0	5	7
1010	G.H1.12	G.H5.04	0.975833	No	No	0	0	8
1011	G.HN.31	G.HN.32	0.962431	No	No	0	3	6
1012	8x51	8x55	0.954588	No	No	0	8	4
1013	4x51	4x55	0.954154	No	No	0	4	4
1014	1x38	1x42	0.951702	No	No	0	5	7
1015	G.HN.42	G.HN.45	0.946023	No	No	0	5	4
1016	G.HG.10	G.HG.12	0.944306	No	No	0	5	3
1017	G.hgh4.12	G.hgh4.15	0.940833	No	No	0	1	2
1018	H.HC.11	H.HE.06	0.935707	Yes	No	0	0	0
1019	6x39	7x52	0.930793	No	No	0	7	8
1020	4x40	4x44	0.920196	No	No	0	4	3
1021	G.HN.45	G.HN.49	0.897689	No	No	0	4	4
1022	4x55	4x59	0.89355	No	No	0	4	7
1023	5x62	5x63	0.883249	Yes	No	0	6	3
1024	b.ntx4	g.ntx8	0.875833	No	No	0	0	0
1025	g.ctx6	g.h2x16	0.87146	Yes	No	0	6	4
1026	3x21	E1x50	0.86267	No	Yes	0	8	7
1027	7x36	7x37	0.8623	No	No	0	5	6
1028	G.s3h2.01	G.s3h2.02	0.855158	No	No	0	9	9
1029	G.H1.06	G.H1.07	0.844977	No	Yes	0	9	9
1030	1x30	1x31	0.833792	No	Yes	0	0	0
1031	G.hgh4.07	G.hgh4.09	0.829838	No	No	0	2	5
1032	b.1x4	b.ntx4	0.81	No	No	0	8	0
1033	8x55	8x59	0.789583	No	No	0	4	4
1034	G.HN.38	G.HN.42	0.774432	No	No	0	2	5
1035	G.s6h5.03	G.s6h5.04	0.761088	No	No	0	9	9
1036	G.HG.10	G.HG.11	0.757102	No	No	0	5	5
1037	G.HN.27	G.HN.28	0.750947	No	No	0	2	2
1038	1x41	1x45	0.734583	No	No	0	5	5
1039	1x29	1x31	0.72979	No	Yes	0	0	0
1040	6x27	6x30	0.721477	No	No	0	0	7
1041	1x28	1x31	0.708333	No	Yes	0	0	0
1042	6x41	6x42	0.706136	No	No	0	8	5
1043	b.l8x3	b.l8x6	0.700501	No	No	0	3	4
1044	5x42	5x46	0.694775	No	No	0	5	4
1045	5x70	5x74	0.67105	No	No	0	4	4
1046	g.h1x6	g.h1x9	0.659943	No	No	0	4	6
1047	7x28	7x32	0.658333	No	No	0	0	1
1048	4x67	4x68	0.655	No	No	0	0	0
1049	G.H3.08	G.H3.11	0.654785	No	No	0	8	8
1050	1x31	1x34	0.651639	Yes	No	0	0	5
1051	H.HA.12	H.hbhc.14	0.645387	Yes	Yes	0	0	0
1052	b.1x1	g.ntx4	0.642862	Yes	No	0	4	0
1053	G.HN.30	G.HN.32	0.62955	No	No	0	4	6
1054	G.s4h3.09	G.s4h3.12	0.627708	Yes	No	0	0	0
1055	7x26	7x28	0.597917	No	No	0	0	0
1056	1x40	1x43	0.586383	No	No	0	4	6
1057	b.1x1	g.ntx3	0.570046	Yes	No	0	4	4
1058	g.h1x2	g.h1x5	0.567971	No	Yes	0	2	6
1059	G.HN.27	G.HN.31	0.565901	No	No	0	2	3
1060	7x27	E3	0.5575	No	Yes	0	0	3
1061	G.H1.09	G.H1.10	0.544815	No	No	0	8	9
1062	1x30	NT	0.535787	No	No	0	0	0
1063	H.HC.04	H.HE.12	0.533148	Yes	No	0	0	0
1064	G.H3.01	G.s4h3.14	0.527593	Yes	No	0	9	6
1065	b.b1x3	g.ctx18	0.50875	Yes	No	0	7	0
1066	5x52	5x56	0.50375	No	No	0	4	4
1067	3x23	3x26	0.501317	No	No	0	1	6
1068	A:A:S366	G.H1.03	0.499792	No	Yes	0	0	9
1069	b.1x3	b.ntx1	0.490107	No	No	0	1	0
1070	5x82	G.H4.13	0.485926	No	Yes	0	2	3
1071	G.H3.01	G.s4h3.09	0.466458	Yes	Yes	0	9	0
1072	b.1x21	g.l1x4	0.465	No	Yes	0	3	8
1073	H.HC.08	H.HC.12	0.463636	No	No	0	0	0
1074	H.HE.04	H.HF.06	0.443417	Yes	No	0	0	0
1075	5x78	G.H4.13	0.439236	No	Yes	0	4	3
1076	G.s4h3.05	G.s4h3.06	0.418866	No	No	0	9	8
1077	6x46	6x47	0.415798	No	No	0	6	8
1078	G.s4h3.09	G.s4h3.13	0.41375	Yes	No	0	0	0
1079	5x73	5x77	0.40294	No	No	0	4	4
1080	5x58	6x38	0.3925	Yes	No	0	9	6
1081	5x77	G.hgh4.13	0.385833	No	No	0	4	4
1082	g.h1x1	g.ntx1	0.384444	No	No	0	2	3
1083	G.hfs2.05	G.s3h2.02	0.381111	No	No	0	9	9
1084	5x81	G.hgh4.09	0.380556	No	No	0	2	5
1085	g.h1x1	g.ntx6	0.38	No	No	0	2	0
1086	H.HF.01	H.HF.02	0.362593	No	No	0	0	0
1087	H.HE.05	H.HF.03	0.359832	Yes	No	0	0	0
1088	6x28	6x31	0.356157	No	No	0	0	5
1089	8x56	8x60	0.341667	No	No	0	4	9
1090	6x26	6x27	0.333843	No	No	0	0	0
1091	H.HE.04	H.HF.03	0.330875	Yes	No	0	0	0
1092	H.HA.20	H.HB.13	0.328131	No	No	0	0	0
1093	H.hbhc.01	H.hbhc.04	0.322172	No	No	0	0	0
1094	G.s4h3.11	G.s4h3.13	0.314259	No	No	0	0	0
1095	g.h2x10	g.h2x13	0.311088	No	No	0	3	1
1096	g.h2x3	g.h2x6	0.30146	No	No	0	5	2
1097	H.HE.08	H.HE.11	0.291229	No	No	0	0	0
1098	5x83	G.H4.17	0.287778	No	No	0	0	4
1099	G.HN.35	G.HN.38	0.287612	No	No	0	4	2
1100	2x66	2x67	0.28584	No	No	0	4	4
1101	H.HA.19	H.HC.11	0.282778	No	Yes	0	0	0
1102	H.hehf.04	H.hehf.06	0.273939	Yes	No	0	0	0
1103	7x26	7x29	0.272917	No	No	0	0	0
1104	G.s4h3.09	G.s4h3.10	0.266458	Yes	No	0	0	0
1105	H.HB.08	H.HB.12	0.263367	No	No	0	0	0
1106	H.HC.01	H.HC.02	0.262037	No	No	0	0	0
1107	4x63	4x66	0.2575	No	No	0	5	0
1108	H.HD.07	H.HE.03	0.256212	Yes	No	0	0	0
1109	H.HA.12	H.hbhc.13	0.256111	Yes	No	0	0	0
1110	g.h1x3	g.ntx7	0.253333	No	No	0	3	0
1111	H.HB.09	H.HC.03	0.24729	No	Yes	0	0	0
1112	H.HB.05	H.HC.06	0.247003	Yes	No	0	0	0
1113	g.ntx5	g.ntx6	0.243333	No	No	0	0	0
1114	H.HA.16	H.HC.03	0.240253	No	Yes	0	0	0
1115	6x25	G.h4s6.11	0.239583	No	No	0	0	2
1116	H.HF.02	H.hehf.07	0.238249	No	No	0	0	0
1117	H.hehf.04	H.hehf.05	0.233704	Yes	No	0	0	0
1118	H.hbhc.02	b.b9x3	0.232963	No	Yes	0	0	6
1119	G.S2.05	G.hfs2.03	0.23	No	No	0	4	0
1120	G.hfs2.01	H.HE.05	0.228064	No	Yes	0	0	0
1121	H.hbhc.04	H.hbhc.14	0.227273	No	Yes	0	0	0
1122	2x37	I1x52	0.226667	No	No	0	5	8
1123	G.H1.09	G.h1ha.01	0.218333	No	No	0	8	0
1124	1x33	E1	0.218333	No	No	0	6	0
1125	8x55	CT	0.211852	No	No	0	4	0
1126	3x52	I2	0.211458	No	No	0	4	6
1127	G.H3.01	G.s4h3.08	0.20875	Yes	No	0	9	0
1128	H.HA.15	H.HE.09	0.204141	No	No	0	0	0
1129	6x24	6x26	0.20125	No	No	0	0	0
1130	H.HB.08	H.HC.06	0.19803	No	No	0	0	0
1131	H.HF.04	H.hehf.06	0.196364	No	No	0	0	0
1132	A:A:Q59	G.S2.06	0.195	No	Yes	0	0	9
1133	H.HD.09	H.HD.12	0.193788	No	No	0	0	0
1134	5x86	G.hgh4.04	0.188704	No	Yes	0	0	6
1135	H.HC.08	H.HE.10	0.188485	No	No	0	0	0
1136	8x61	8x62	0.187917	No	No	0	0	0
1137	G.hgh4.17	G.hgh4.19	0.186364	No	No	0	4	7
1138	H.HA.16	H.HB.12	0.181347	No	No	0	0	0
1139	H.HC.04	H.hbhc.14	0.180522	Yes	Yes	0	0	0
1140	H.hdhe.05	b.l5x2	0.180455	No	No	0	0	6
1141	H.hbhc.03	b.l5x2	0.176481	No	No	0	0	6
1142	H.HA.15	H.HA.19	0.175404	No	No	0	0	0
1143	H.HC.04	H.HE.09	0.175	Yes	No	0	0	0
1144	b.l21x6	b.l21x7	0.174975	No	Yes	0	3	5
1145	H.HE.04	H.HE.08	0.172845	Yes	No	0	0	0
1146	H.HA.29	H.HD.09	0.165606	No	No	0	0	0
1147	H.HC.04	H.HE.13	0.162879	Yes	No	0	0	0
1148	H.HA.11	H.HE.05	0.156515	No	Yes	0	0	0
1149	4x68	4x69	0.153333	No	No	0	0	0
1150	H.HD.09	H.hahb.02	0.152879	No	No	0	0	0
1151	H.HB.02	H.HC.10	0.14798	Yes	No	0	0	0
1152	H.hahb.06	H.hchd.01	0.143939	No	Yes	0	0	0
1153	G.s2s3.02	H.HA.09	0.143788	No	No	0	4	0
1154	H.hdhe.02	b.b5x8	0.143485	No	No	0	0	5
1155	5x81	5x84	0.141852	No	No	0	2	0
1156	H.HA.17	H.HA.20	0.140926	No	No	0	0	0
1157	H.HE.04	H.HF.02	0.140471	Yes	No	0	0	0
1158	H.HD.03	H.hchd.01	0.137643	No	Yes	0	0	0
1159	H.HA.09	H.HA.12	0.137037	No	Yes	0	0	0
1160	H.HB.02	H.HB.06	0.136852	Yes	No	0	0	0
1161	G.hfs2.03	H.HA.10	0.135185	No	No	0	0	0
1162	H.HB.05	H.HC.09	0.135084	Yes	No	0	0	0
1163	H.hahb.01	H.hahb.02	0.133939	No	No	0	0	0
1164	H.HA.02	H.HA.03	0.133148	No	No	0	0	0
1165	H.HA.16	H.hbhc.14	0.131667	No	Yes	0	0	0
1166	g.l1x2	g.l1x3	0.131397	No	No	0	2	1
1167	G.hfs2.02	H.HF.05	0.128788	No	No	0	0	0
1168	G.hfs2.04	G.hfs2.06	0.1275	No	No	0	0	7
1169	H.HA.20	H.HA.21	0.125808	No	No	0	0	0
1170	H.HC.03	H.hbhc.15	0.123973	Yes	No	0	0	0
1171	G.S2.03	G.h1ha.02	0.121667	No	No	0	9	0
1172	H.HD.01	H.hchd.01	0.12037	No	Yes	0	0	0
1173	G.s1h1.04	G.s4h3.07	0.11875	Yes	No	0	9	0
1174	H.HB.10	H.HB.13	0.11665	No	No	0	0	0
1175	H.HC.02	H.HC.06	0.11596	No	No	0	0	0
1176	H.HA.08	H.hehf.04	0.114697	No	Yes	0	0	0
1177	5x80	I3	0.114375	No	No	0	4	0
1178	H.HB.08	H.HB.11	0.113502	No	No	0	0	0
1179	H.HB.04	H.HB.05	0.113333	No	Yes	0	0	0
1180	H.HE.01	H.HE.05	0.110623	No	Yes	0	0	0
1181	H.HE.12	H.hehf.04	0.109848	No	Yes	0	0	0
1182	H.HB.02	H.HB.05	0.109545	Yes	Yes	0	0	0
1183	G.H1.03	G.h1ha.05	0.108333	Yes	No	0	9	0
1184	G.hfs2.01	H.HA.14	0.106061	No	No	0	0	0
1185	H.HB.02	H.hchd.01	0.10197	Yes	Yes	0	0	0
1186	H.HD.07	H.HD.08	0.10197	Yes	No	0	0	0
1187	H.HA.25	H.hdhe.01	0.101061	No	Yes	0	0	0
1188	H.HA.03	H.HA.07	0.1	No	No	0	0	0
1189	H.HD.07	H.HD.10	0.0963636	Yes	No	0	0	0
1190	H.HC.03	H.HC.07	0.093266	Yes	No	0	0	0
1191	G.h4s6.04	G.h4s6.08	0.0932008	No	No	0	4	5
1192	H.HA.26	H.hahb.04	0.0922727	No	No	0	0	0
1193	G.s2s3.02	H.HA.06	0.0910606	No	No	0	4	0
1194	H.HC.11	H.HD.04	0.0909091	Yes	No	0	0	0
1195	H.HA.21	H.hdhe.03	0.0893939	No	No	0	0	0
1196	H.HB.14	b.b9x2	0.0892593	No	No	0	0	5
1197	H.HC.11	H.HD.07	0.0877273	Yes	Yes	0	0	0
1198	H.HC.08	H.HC.11	0.0859259	No	Yes	0	0	0
1199	H.HA.02	H.HA.04	0.085	No	No	0	0	0
1200	H.HC.11	H.HE.07	0.0845455	Yes	No	0	0	0
1201	H.HA.14	H.HA.17	0.0839562	No	No	0	0	0
1202	H.HB.02	H.hahb.08	0.0825758	Yes	No	0	0	0
1203	H.HD.02	H.hchd.01	0.0818687	No	Yes	0	0	0
1204	H.HA.10	H.HA.14	0.0816667	No	No	0	0	0
1205	H.HA.18	H.hdhe.04	0.0792424	No	No	0	0	0
1206	H.hehf.01	H.hehf.03	0.0790909	No	No	0	0	0
1207	H.HA.12	H.HA.13	0.0777778	Yes	No	0	0	0
1208	H.HD.06	H.hahb.04	0.0775758	No	No	0	0	0
1209	5x85	G.hgh4.07	0.0774074	No	No	0	0	2
1210	H.HD.10	H.hdhe.01	0.0771212	No	Yes	0	0	0
1211	H.HA.22	H.HD.07	0.0733333	No	Yes	0	0	0
1212	H.HA.06	H.HA.07	0.0732323	No	No	0	0	0
1213	H.HA.29	H.hdhe.01	0.0710606	No	Yes	0	0	0
1214	g.ctx12	g.ctx19	0.0695455	No	No	0	6	0
1215	H.HD.01	H.hahb.07	0.0686364	No	No	0	0	0
1216	H.HA.23	H.HC.10	0.0677273	No	No	0	0	0
1217	G.HN.42	H.HA.28	0.0636364	No	No	0	5	0
1218	H.HD.06	H.hdhe.01	0.0610606	No	Yes	0	0	0
1219	G.H1.07	G.h1ha.20	0.0609259	Yes	No	0	9	0
1220	H.HA.18	H.HE.02	0.0602694	No	No	0	0	0
1221	H.HD.11	b.l8x5	0.059697	No	Yes	0	0	3
1222	g.ntx2	g.ntx4	0.0592593	No	No	0	4	0
1223	H.HA.24	b.b13x2	0.0561111	No	No	0	0	4
1224	G.hfs2.02	H.HE.01	0.0516667	No	No	0	0	0
1225	H.HE.02	H.hdhe.03	0.0477273	No	No	0	0	0
1226	2x67	2x68	0.0439583	No	No	0	4	0
1227	H.HC.04	H.HC.05	0.0414815	Yes	No	0	0	0
1228	H.hahb.05	H.hahb.06	0.0401515	No	No	0	0	0
1229	H.HB.04	H.HB.07	0.0400673	No	No	0	0	0
1230	H.HB.01	H.HB.02	0.0398485	No	Yes	0	0	0
1231	H.hehf.01	H.hehf.04	0.0380471	No	Yes	0	0	0
1232	6x62	E3	0.0362963	No	Yes	0	0	3
1233	H.HB.02	H.hahb.09	0.0301852	Yes	No	0	0	0
1234	H.hahb.02	H.hahb.03	0.0295455	No	No	0	0	0
1235	H.HD.02	H.HD.05	0.0295455	No	No	0	0	0
1236	H.HA.05	H.HA.09	0.0281481	No	No	0	0	0
1237	H.HA.27	H.hahb.03	0.0269697	No	No	0	0	0
1238	H.HB.03	H.HB.07	0.0198485	No	No	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.S1.06	4.82113	4	18	8
2	G.s1h1.04	3.7781	4	19	9
3	G.H1.03	0.76296	4	0	9
4	G.H1.07	0.990608	4	0	9
5	G.S2.06	3.62884	5	0	9
6	G.S3.03	5.81841	6	7	8
7	G.S3.04	8.33017	4	17	7
8	G.S3.06	9.10719	4	17	7
9	G.H2.06	5.36444	5	1	9
10	G.H2.07	4.99851	6	1	9
11	G.h2s4.01	8.68013	4	0	9
12	G.S4.04	3.79789	5	0	9
13	G.s4h3.04	5.26071	4	0	8
14	G.H3.01	3.33708	7	19	9
15	G.H3.06	4.95339	4	0	6
16	G.H3.09	4.78225	6	20	9
17	G.H3.13	8.8292	5	20	6
18	G.H3.17	8.19315	5	3	5
19	G.S5.04	4.10069	4	0	9
20	G.S5.05	4.39545	5	8	9
21	G.S5.07	4.19275	4	8	9
22	G.HG.03	3.85608	4	0	6
23	G.hgh4.01	4.2908	4	0	6
24	G.hgh4.04	1.7856	4	0	6
25	G.hgh4.05	7.6857	6	14	6
26	G.hgh4.08	5.08834	5	14	6
27	G.hgh4.11	2.714	4	0	5
28	G.hgh4.21	4.92962	4	0	4
29	G.H4.03	2.62186	4	0	4
30	G.H4.07	6.66143	4	9	5
31	G.H4.08	3.988	4	0	3
32	G.H4.10	7.64467	5	14	7
33	G.H4.12	5.75589	4	9	4
34	G.H4.13	2.86288	4	0	3
35	G.H4.15	6.99364	4	0	8
36	G.h4s6.03	1.53213	4	0	4
37	G.h4s6.12	3.48805	4	0	2
38	G.h4s6.20	4.77357	4	10	4
39	G.S6.02	7.53313	5	10	8
40	G.S6.05	9.00419	4	9	5
41	G.H5.03	4.08531	5	8	9
42	G.H5.05	4.96364	4	7	5
43	G.H5.08	4.70488	7	7	8
44	G.H5.13	4.51026	4	10	8
45	G.H5.17	5.59044	5	10	5
46	G.H5.19	3.30878	4	4	8
47	G.H5.20	3.85361	4	0	8
48	G.H5.23	6.42418	4	0	4
49	b.1x1	1.45056	4	0	4
50	b.1x16	2.28777	4	0	4
51	b.lhb1x3	2.81217	4	0	2
52	b.b1x3	3.65515	4	0	7
53	b.l1x3	8.04712	6	6	9
54	b.l1x6	9.00662	5	3	9
55	b.b2x1	5.81737	5	3	8
56	b.b2x5	5.62124	6	0	7
57	b.b3x3	3.78888	4	0	8
58	b.l3x1	6.91563	4	3	9
59	b.l3x2	5.62381	5	6	9
60	b.b4x3	3.81333	4	15	7
61	b.b4x6	9.2652	6	6	9
62	b.b5x2	6.45594	4	0	7
63	b.b5x3	5.84408	6	6	9
64	b.b5x5	4.80955	4	0	5
65	b.b5x7	5.01856	4	0	7
66	b.l5x1	3.99013	5	15	8
67	b.l5x5	7.90125	6	0	9
68	b.b6x5	3.94257	6	0	6
69	b.l6x5	5.59039	4	16	4
70	b.b7x1	5.60688	5	16	4
71	b.b8x4	5.50656	5	15	6
72	b.l8x5	2.22939	5	0	3
73	b.b9x3	3.34194	4	0	6
74	b.l9x3	7.18057	5	1	9
75	b.l9x6	4.91481	7	1	8
76	b.b10x5	4.29911	6	0	9
77	b.l11x2	7.56149	4	1	9
78	b.b12x6	7.81948	7	1	8
79	b.b13x7	7.28687	5	5	7
80	b.l13x3	7.23354	6	5	9
81	b.l13x6	5.05926	4	1	9
82	b.b14x3	4.0706	4	5	5
83	b.b15x1	6.29166	5	5	9
84	b.b15x2	6.06771	4	1	6
85	b.l15x1	5.18683	4	1	7
86	b.l15x2	5.24502	5	5	9
87	b.b16x4	9.89607	4	5	6
88	b.b16x5	4.5504	4	0	5
89	b.b16x6	7.53718	7	5	8
90	b.b17x5	6.86298	4	1	7
91	b.b17x7	7.70916	4	1	8
92	b.l17x3	8.25489	6	1	9
93	b.l17x6	6.55681	5	1	9
94	b.b18x3	4.90021	4	1	8
95	b.b18x5	4.85351	4	0	5
96	b.l18x1	5.937	7	12	6
97	b.l18x2	5.59458	4	12	7
98	b.b19x2	7.24724	5	1	6
99	b.b19x4	5.62185	4	1	8
100	b.l19x2	6.33662	5	1	9
101	b.b20x4	10.2141	5	1	8
102	b.b20x6	6.30665	6	1	6
103	b.b20x7	4.40445	4	0	9
104	b.l20x2	6.36922	4	0	9
105	b.b21x1	8.21901	4	1	7
106	b.b21x5	4.73284	4	0	4
107	b.b21x7	5.38387	6	0	5
108	b.l21x2	5.4323	4	0	4
109	b.l21x7	3.53059	4	3	5
110	b.b22x5	5.40177	5	12	7
111	b.l22x5	6.23373	5	21	9
112	b.b23x6	6.25847	7	3	7
113	b.l23x1	5.70473	5	3	6
114	b.b24x4	7.73507	4	3	6
115	b.b24x6	6.8768	4	3	8
116	b.l24x3	3.77808	5	0	5
117	b.l25x3	7.86195	5	11	9
118	b.l25x6	11.2864	5	3	8
119	b.b26x3	3.81434	4	0	6
120	b.l28x1	9.89566	7	3	9
121	b.l28x2	7.60882	4	11	9
122	b.b28x3	3.89557	4	0	7
123	b.b28x4	7.44507	4	11	6
124	b.b28x6	7.92106	5	11	9
125	g.h1x5	1.97199	4	0	6
126	g.h1x8	2.11913	4	0	7
127	g.h1x12	2.19805	4	0	6
128	g.l1x4	3.92078	5	0	8
129	g.h2x11	8.66956	4	12	6
130	g.ctx3	5.58598	5	0	9
131	g.ctx6	2.98521	4	0	6
132	g.ctx15	6.15235	4	13	9
133	g.ctx16	4.76714	6	13	8
134	1x57	3.57049	4	0	7
135	1x60	3.33618	5	0	6
136	2x42	4.07269	5	4	8
137	2x46	4.35132	4	4	9
138	2x50	6.0119	5	4	9
139	2x56	4.69816	4	2	7
140	2x57	4.06144	4	2	7
141	2x65	1.25319	4	0	5
142	E1x50	4.87818	7	26	7
143	E1x52	4.2332	5	0	6
144	3x28	4.88839	4	0	5
145	3x46	3.43879	4	4	9
146	3x49	5.4653	4	4	8
147	3x50	5.94736	4	4	9
148	3x51	7.2691	4	0	8
149	I2x51	3.98098	4	7	6
150	I2x53	5.81573	5	4	7
151	E2	10.1162	16	2	3
152	5x39	4.44969	4	2	7
153	5x47	6.07201	6	2	8
154	5x58	3.43969	6	0	9
155	5x62	3.38972	4	0	6
156	6x44	4.49023	4	2	9
157	6x48	5.7482	8	2	8
158	6x49	2.8577	4	0	6
159	6x51	5.99143	5	2	6
160	6x52	6.96214	5	2	7
161	E3	2.73807	9	2	3
162	7x39	5.20762	4	2	6
163	7x42	6.02187	7	2	7
164	7x49	6.22741	4	4	9
165	7x53	4.91074	5	4	9
166	8x50	3.98123	6	25	8
167	8x54	3.32564	4	0	7
168	Lig	6.00313	14	2	0
169	1x31	0.730889	4	0	0
170	H.HA.12	0.279078	4	0	0
171	H.HB.02	0.092708	7	0	0
172	H.HB.05	0.151242	4	0	0
173	H.hbhc.14	0.296212	4	0	0
174	H.HC.03	0.176195	4	0	0
175	H.HC.04	0.218606	5	0	0
176	H.HC.11	0.261265	6	0	0
177	H.hchd.01	0.117158	5	0	0
178	H.HD.07	0.123121	5	0	0
179	H.hdhe.01	0.0775758	4	0	0
180	H.HE.04	0.271902	4	0	0
181	H.HE.05	0.213758	4	0	0
182	H.hehf.04	0.154047	5	0	0
183	G.s4h3.09	0.443594	4	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.l1x3	b.l3x2	35.3844	3.22265	Yes	Yes	6	9	9
2	b.b4x6	b.l1x3	33.2143	3.78362	Yes	Yes	6	9	9
3	b.l1x4	b.l3x2	36.4017	7.6183	No	Yes	0	6	9
4	G.hns1.01	b.l1x4	36.6944	3.61949	No	No	0	4	6
5	G.S1.03	G.hns1.01	36.7676	10.1931	No	No	0	9	4
6	G.S1.03	G.S3.06	36.8407	4.08073	No	Yes	0	9	7
7	G.S3.06	b.l5x5	44.0849	16.6379	Yes	Yes	0	7	9
8	G.h2s4.01	b.l5x5	66.8706	11.2892	Yes	Yes	0	9	9
9	G.S1.05	G.h2s4.01	65.9291	16.2429	No	Yes	0	9	9
10	G.S1.05	G.S1.07	66.1208	4.02893	No	No	0	9	8
11	G.S1.07	G.S4.04	66.2486	3.25884	No	Yes	0	8	9
12	G.S4.04	G.S4.06	24.7355	3.23438	Yes	No	0	9	7
13	G.H4.15	G.S4.06	24.7539	6.01611	Yes	No	0	8	7
14	G.H3.06	G.H4.15	74.6982	8.36935	Yes	Yes	0	6	8
15	G.H3.06	G.H4.14	99.7775	4.04909	Yes	No	0	6	5
16	G.H4.10	G.H4.14	99.6333	7.4234	Yes	No	0	7	5
17	G.H4.10	G.hgh4.05	99.3645	14.1215	Yes	Yes	14	7	6
18	G.HG.15	G.hgh4.05	100	9.05058	No	Yes	0	7	6
19	G.HG.15	G.s4h3.04	99.9824	7.22763	No	Yes	0	7	8
20	G.HG.07	G.s4h3.04	99.8647	7.63059	No	Yes	0	9	8
21	G.HG.07	G.s4h3.02	99.847	2.6965	No	No	0	9	9
22	G.HG.03	G.s4h3.02	99.8292	4.56955	Yes	No	0	6	9
23	G.HG.03	G.s5hg.01	99.7581	5.98004	Yes	No	0	6	9
24	G.S5.07	G.s5hg.01	99.3595	4.52637	Yes	No	0	9	9
25	G.S5.07	G.s6h5.01	99.1825	4.97909	Yes	No	8	9	9
26	G.S5.05	G.s6h5.01	98.8193	6.67023	Yes	No	8	9	9
27	G.H5.07	G.S5.05	20.6195	3.57391	No	Yes	0	9	9
28	G.H5.07	G.S4.03	20.5888	3.35711	No	No	0	9	7
29	G.S1.04	G.S4.03	20.0431	4.06306	No	No	0	7	7
30	G.S1.04	G.S3.03	20.0108	4.24416	No	Yes	0	7	8
31	G.H3.09	G.S4.04	49.6259	4.62023	Yes	Yes	0	9	9
32	G.H3.09	G.H4.15	25.0528	6.6024	Yes	Yes	0	9	8
33	G.S4.04	G.S5.04	25.0902	2.95049	Yes	Yes	0	9	9
34	G.H4.15	G.S5.04	24.9051	6.98671	Yes	Yes	0	8	9
35	G.H3.09	G.h4s6.01	25.0692	5.46595	Yes	No	0	9	4
36	G.H3.06	G.h4s6.01	25.1314	3.06537	Yes	No	0	6	4
37	G.H5.08	G.S3.03	19.592	3.12967	Yes	Yes	7	8	8
38	G.H2.07	b.l9x6	33.3855	4.053	Yes	Yes	1	9	8
39	G.H2.06	b.l17x6	16.4947	7.23087	Yes	Yes	1	9	9
40	G.H2.06	b.l9x6	16.7743	3.3453	Yes	Yes	1	9	8
41	G.H2.04	G.H2.07	32.9505	5.87247	No	Yes	0	9	9
42	G.H2.04	G.H3.08	33.0041	4.71566	No	No	0	9	8
43	G.H3.17	b.l28x1	18.3467	4.56951	Yes	Yes	3	5	9
44	b.l1x6	b.l28x1	12.2575	20.5089	Yes	Yes	3	9	9
45	b.l1x6	b.l3x1	12.4812	6.92818	Yes	Yes	3	9	9
46	b.l3x1	b.l5x5	24.9715	6.98449	Yes	Yes	0	9	9
47	b.l25x6	b.l28x1	17.228	20.2383	Yes	Yes	3	8	9
48	b.b2x1	b.l28x1	24.2082	6.11133	Yes	Yes	3	8	9
49	b.b2x1	b.l3x1	12.3436	10.3336	Yes	Yes	3	8	9
50	G.H3.17	b.l23x1	16.5604	4.41759	Yes	Yes	3	5	6
51	b.l23x1	b.l25x6	16.5577	13.5614	Yes	Yes	3	6	8
52	G.H5.10	G.S6.02	78.2059	12.2038	No	Yes	0	7	8
53	G.H5.10	G.S5.03	39.1058	9.52958	No	No	0	7	9
54	G.S5.03	G.S5.05	39.1637	3.18759	No	Yes	0	9	9
55	G.H5.10	G.S6.04	39.1629	9.78674	No	No	0	7	9
56	G.S5.05	G.S6.04	39.1261	4.00873	Yes	No	0	9	9
57	G.H5.17	G.S6.02	38.8377	5.82092	Yes	Yes	10	5	8
58	G.H5.13	G.S6.02	38.909	5.94479	Yes	Yes	10	8	8
59	G.H5.08	G.H5.12	19.3981	3.53012	Yes	No	7	8	7
60	5x68	G.H5.13	38.7151	5.18813	No	Yes	10	7	8
61	5x68	G.H5.16	77.297	4.42805	No	No	0	7	6
62	G.H5.16	I2x50	77.1582	3.91181	No	No	0	6	8
63	5x68	G.H5.17	38.721	6.96073	No	Yes	10	7	5
64	G.H5.12	I2x50	19.3796	3.63635	No	No	0	7	8
65	G.H5.15	I2x50	96.3587	3.78308	No	No	0	8	8
66	G.H5.15	G.H5.19	96.009	3.13027	No	Yes	0	8	8
67	3x53	G.H5.19	64.0369	3.27157	No	Yes	4	8	8
68	G.H5.19	I2x53	31.6225	3.19493	Yes	Yes	4	8	7
69	3x48	5x57	28.451	3.66115	No	No	0	6	7
70	3x48	3x52	28.627	3.70977	No	No	0	6	4
71	3x52	I2x53	28.9575	3.97156	No	Yes	0	4	7
72	3x53	G.H5.23	63.8626	3.10657	No	Yes	0	8	4
73	3x50	G.H5.23	63.3358	13.3503	Yes	Yes	0	9	4
74	b.l17x5	b.l17x6	16.3661	3.15531	No	Yes	1	6	9
75	b.l17x5	b.l19x2	16.2929	4.20211	No	Yes	1	6	9
76	b.l17x3	b.l19x2	11.198	5.0257	Yes	Yes	1	9	9
77	b.b17x7	b.b20x6	12.523	8.85532	Yes	Yes	1	8	6
78	b.b17x7	b.b21x1	11.6012	4.01892	Yes	Yes	1	8	7
79	b.1x19	b.b21x1	10.2197	8.23876	No	Yes	0	6	7
80	b.l21x7	b.l23x1	32.2243	3.86769	Yes	Yes	3	5	6
81	b.b23x6	b.l21x7	29.5398	3.0435	Yes	Yes	3	7	5
82	b.b23x6	b.b24x6	23.7236	6.7958	Yes	Yes	3	7	8
83	b.b21x7	b.b24x6	22.8312	9.06722	Yes	Yes	0	5	8
84	b.l27x5	g.ctx15	10.2835	5.14335	No	Yes	0	5	9
85	b.l27x5	g.ctx4	20.2863	5.29807	No	No	0	5	7
86	g.ctx3	g.ctx4	20.1336	3.67739	Yes	No	0	9	7
87	b.l22x1	g.ctx3	15.5447	6.87708	No	Yes	0	9	9
88	b.b23x1	b.l22x1	15.3915	3.61241	No	No	0	5	9
89	b.b23x1	b.b24x5	14.932	4.8911	No	No	0	5	5
90	b.b23x3	b.b24x5	14.6256	4.02758	No	No	0	7	5
91	b.b23x3	b.b26x3	13.3966	3.11018	No	Yes	0	7	6
92	b.b26x3	b.b27x3	12.9372	3.88846	Yes	No	0	6	8
93	b.b27x3	b.l25x3	11.116	6.20609	No	Yes	0	8	9
94	b.b1x6	b.b4x6	20.5247	17.7452	No	Yes	0	9	9
95	b.b1x6	b.b28x5	20.4561	3.04941	No	No	0	9	5
96	b.b2x1	b.b6x1	12.0443	3.4469	Yes	No	0	8	9
97	b.b3x2	b.b4x6	11.0676	4.84567	No	Yes	0	5	9
98	b.b2x5	b.b3x2	10.9929	8.00902	Yes	No	0	7	5
99	b.b2x5	b.l27x1	10.5388	10.7175	Yes	No	0	7	8
100	b.l27x1	b.l27x3	10.2339	6.46716	No	No	22	8	7
101	b.l27x3	b.l27x5	10.1642	7.02972	No	No	0	7	5
102	b.b21x7	b.b23x2	10.7469	4.45218	Yes	No	0	5	6
103	7x42	Lig	15.7843	4.13169	Yes	Yes	2	7	0
104	6x48	Lig	49.5396	3.91619	Yes	Yes	2	8	0
105	6x44	6x48	36.1739	5.85625	Yes	Yes	2	9	8
106	5x54	6x44	44.7351	4.27127	No	Yes	0	8	9
107	3x47	5x54	45.0905	4.28786	No	No	0	9	8
108	3x47	5x57	22.759	3.29571	No	No	0	9	7
109	3x47	5x58	22.7376	4.37971	No	Yes	0	9	9
110	3x50	5x58	26.1505	3.3903	Yes	Yes	0	9	9
111	6x48	7x45	18.1148	8.32268	Yes	No	0	8	9
112	7x45	7x49	18.6464	7.66426	No	Yes	0	9	9
113	3x43	7x49	25.9813	5.26348	No	Yes	4	8	9
114	3x43	7x53	35.3027	7.85644	No	Yes	4	8	9
115	3x50	7x53	36.6888	3.89019	Yes	Yes	4	9	9
116	2x50	7x46	10.4213	8.07796	Yes	No	0	9	9
117	2x53	7x46	10.0641	5.23133	No	No	0	8	9
118	E2	Lig	20.5696	3.06491	Yes	Yes	2	3	0
119	b.b28x5	g.ctx16	20.2287	4.15722	No	Yes	13	5	8
120	g.ctx15	g.ctx16	11.283	4.26198	Yes	Yes	13	9	8
121	G.H3.08	G.S4.04	33.135	4.92549	No	Yes	0	8	9
122	b.b6x1	b.l9x6	12.2501	5.70162	No	Yes	0	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x56	3x32	8.00363	2	Yes	No	7	7	2	1
2x56	7x42	4.26723	2	Yes	Yes	7	7	2	1
2x57	7x39	2.95742	2	Yes	Yes	7	6	2	2
2x57	7x42	5.47387	2	Yes	Yes	7	7	2	1
3x22	E2	3.61479	0	No	Yes	3	3	2	1
3x32	7x42	9.43421	2	No	Yes	7	7	1	1
3x32	Lig	11.6539	2	No	Yes	7	0	1	0
3x33	4x57	7.29312	0	No	No	5	7	1	2
3x33	Lig	11.8734	0	No	Yes	5	0	1	0
3x36	6x48	3.88094	2	No	Yes	7	8	1	1
3x36	Lig	8.04707	2	No	Yes	7	0	1	0
3x37	5x461	4.01622	0	No	No	6	5	2	1
3x40	6x44	4.32164	2	No	Yes	7	9	2	2
3x40	6x48	6.78801	2	No	Yes	7	8	2	1
4x61	E2	4.12995	2	No	Yes	5	3	2	1
4x63	E2	3.43578	2	No	Yes	5	3	2	1
4x64	E2	5.33188	0	No	Yes	7	3	2	1
E2	E2	48.0505	2	Yes	Yes	3	3	1	1
E2	E2x52	8.50518	2	Yes	No	3	4	1	1
5x39	E2	5.91757	2	Yes	Yes	7	3	2	1
5x36	E2	3.73016	2	No	Yes	4	3	2	1
E2	E3	3.11186	2	Yes	Yes	3	3	1	2
E2	E2x51	9.91292	2	Yes	No	3	3	1	2
E2x52	Lig	3.82682	2	No	Yes	4	0	1	0
5x40	E2	4.83699	2	No	Yes	5	3	2	1
E2	Lig	3.06491	2	Yes	Yes	3	0	1	0
5x36	5x39	4.25393	2	No	Yes	4	7	2	2
5x39	5x43	4.29649	2	Yes	No	7	5	2	1
5x43	Lig	3.57205	0	No	Yes	5	0	1	0
5x44	6x52	4.02099	0	No	Yes	6	7	2	1
5x461	Lig	3.16893	0	No	Yes	5	0	1	0
5x47	6x44	3.51176	2	Yes	Yes	8	9	2	2
5x47	6x48	3.40843	2	Yes	Yes	8	8	2	1
5x47	6x52	15.8212	2	Yes	Yes	8	7	2	1
6x44	6x48	5.85625	2	Yes	Yes	9	8	2	1
6x48	6x52	4.20186	2	Yes	Yes	8	7	1	1
6x48	7x41	9.61122	2	Yes	No	8	7	1	1
6x48	7x45	8.32268	2	Yes	No	8	9	1	2
6x48	Lig	3.91619	2	Yes	Yes	8	0	1	0
6x51	6x52	4.96576	2	Yes	Yes	6	7	1	1
6x51	7x34	4.20164	2	Yes	No	6	4	1	2
6x51	7x38	6.28484	2	Yes	No	6	5	1	1
6x51	Lig	9.67108	2	Yes	Yes	6	0	1	0
6x52	Lig	5.80089	2	Yes	Yes	7	0	1	0
6x55	Lig	2.96054	2	No	Yes	5	0	1	0
7x38	7x42	7.03473	2	No	Yes	5	7	1	1
7x38	Lig	7.95797	2	No	Yes	5	0	1	0
7x39	7x42	7.18264	2	Yes	Yes	6	7	2	1
7x42	Lig	4.13169	2	Yes	Yes	7	0	1	0
2x60	7x42	4.62871	0	No	Yes	6	7	2	1
E3	E3	3.5148	2	Yes	Yes	3	3	2	2
3x26	E2	4.77976	2	No	Yes	6	3	2	1
6x51	6x55	4.83384	2	Yes	No	6	5	1	1
4x65	E2	4.28604	0	No	Yes	0	3	2	1
7x41	Lig	4.39837	2	No	Yes	7	0	1	0
3x29	E2x52	2.75561	0	No	No	4	4	2	1
4x68	E2	1.10083	2	No	Yes	0	3	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
92.86	Single	2YDV	NECA	2YDV-A_2A-NECA
92.86	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
92.86	Single	5G53	NECA	5G53-A_2A-NECA-Gs
92.86	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
85.71	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
85.71	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
85.71	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
85.71	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
85.71	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
81.25	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
81.25	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
81.25	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
81.25	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
81.25	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
80.00	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
80.00	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
80.00	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
80.00	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
80.00	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
80.00	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
80.00	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
80.00	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
78.57	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
78.57	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
78.57	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
78.57	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
78.57	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
78.57	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
78.57	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
78.57	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
78.57	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
78.57	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
78.57	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
78.57	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
78.57	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
78.57	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
78.57	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
78.57	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
78.57	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
78.57	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
78.57	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
78.57	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
78.57	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
78.57	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
78.57	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
78.57	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
78.57	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
78.57	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
78.57	Consensus	tar_on	Orthosteric Ligand	ta1_on
76.47	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
76.47	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
75.00	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
75.00	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
75.00	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
73.33	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
73.33	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
73.33	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
73.33	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
73.33	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
73.33	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
73.33	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
73.33	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
73.33	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
73.33	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
73.33	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
73.33	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
73.33	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
73.33	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
73.33	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
73.33	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
71.43	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
71.43	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
71.43	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
71.43	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
71.43	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
71.43	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
71.43	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
71.43	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
71.43	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
71.43	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
71.43	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
71.43	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
71.43	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
71.43	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
71.43	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
71.43	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
71.43	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
71.43	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
71.43	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
71.43	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
71.43	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
71.43	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
71.43	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
71.43	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
71.43	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
71.43	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
71.43	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
71.43	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
71.43	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
71.43	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
71.43	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
71.43	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
71.43	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
71.43	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
71.43	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
70.59	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
68.75	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
68.75	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
68.75	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
68.75	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
68.75	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
68.75	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
68.75	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
68.75	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
68.75	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
68.75	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
68.75	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
68.75	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
68.75	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
68.75	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
68.75	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
68.75	Consensus	histamine_off	Orthosteric Ligand	h1_off
68.75	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
68.75	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
66.67	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
66.67	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
66.67	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
66.67	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
66.67	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
66.67	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
66.67	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
66.67	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
66.67	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
66.67	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
66.67	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
66.67	Single	6PS1	Timolol	6PS1-β₂-Timolol
66.67	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
66.67	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
66.67	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
66.67	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
66.67	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
66.67	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
66.67	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
66.67	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
66.67	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
66.67	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
66.67	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
66.67	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
66.67	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
66.67	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
66.67	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
66.67	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
66.67	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
66.67	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
66.67	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
64.71	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
64.71	Single	4LDE	BI167107	4LDE-β₂-BI167107
64.71	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
64.71	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
64.71	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
64.71	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
64.71	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
64.71	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
64.71	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
64.71	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
64.71	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
64.71	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
64.71	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
64.71	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
64.71	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
64.29	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
64.29	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
64.29	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
64.29	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
64.29	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
64.29	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
64.29	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
64.29	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
64.29	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
64.29	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
64.29	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
64.29	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
64.29	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
64.29	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
64.29	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
64.29	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
64.29	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
64.29	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
64.29	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
64.29	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
64.29	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
64.29	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
63.16	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
63.16	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
62.50	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
62.50	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
62.50	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
62.50	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
62.50	Single	6PS6	Timolol	6PS6-β₂-Timolol
62.50	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
62.50	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
62.50	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
62.50	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
62.50	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
62.50	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
62.50	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
62.50	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
62.50	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
62.50	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
62.50	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
62.50	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
62.50	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
62.50	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
61.11	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
61.11	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
61.11	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
61.11	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
61.11	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
60.00	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
60.00	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
60.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
60.00	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
60.00	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
60.00	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
60.00	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
60.00	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
60.00	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
60.00	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
60.00	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
60.00	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
60.00	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
60.00	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
60.00	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
60.00	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
60.00	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
60.00	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
60.00	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
60.00	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
58.82	Single	3P0G	BI167107	3P0G-β₂-BI167107
58.82	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
58.82	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
58.82	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
58.82	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
58.82	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
58.82	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
58.82	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
58.82	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
58.82	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
58.82	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
58.82	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
58.82	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
58.82	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
58.82	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
58.82	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
58.82	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
58.82	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
58.82	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
58.82	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
57.89	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
57.89	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
57.14	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
57.14	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
57.14	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
57.14	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
57.14	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
57.14	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
57.14	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
57.14	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
57.14	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
57.14	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
57.14	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
57.14	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
57.14	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
57.14	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
57.14	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
57.14	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
56.25	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
56.25	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
56.25	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
56.25	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
56.25	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
56.25	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
56.25	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
56.25	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
56.25	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
56.25	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
56.25	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
56.25	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
56.25	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
56.25	Single	7BU7	BI167107	7BU7-β₁-BI167107
56.25	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
56.25	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
56.25	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
56.25	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
56.25	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
56.25	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
56.25	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
56.25	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
56.25	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
56.25	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
56.25	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
56.25	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
56.25	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
56.25	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
56.25	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
56.25	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
56.25	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
56.25	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
56.25	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
56.25	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
55.56	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
55.56	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
55.56	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
55.56	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
55.56	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
55.56	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
55.56	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
55.56	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
55.56	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
55.56	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
55.00	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
55.00	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
55.00	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
54.55	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
53.33	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
53.33	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
53.33	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
53.33	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
53.33	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
53.33	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
53.33	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
53.33	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
53.33	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
53.33	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
53.33	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
53.33	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
53.33	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
53.33	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
53.33	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
53.33	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
53.33	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
53.33	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
53.33	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
53.33	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
53.33	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
53.33	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
53.33	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
53.33	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
53.33	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
53.33	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
52.94	Single	5C1M	BU72	5C1M-μ-BU72
52.94	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
52.94	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
52.94	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
52.94	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
52.94	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
52.94	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
52.94	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
52.94	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
52.94	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
52.94	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
52.94	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
52.94	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
52.94	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
52.94	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
52.94	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
52.94	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
52.63	Single	7EZC	UKA	7EZC-A_2A-UKA
52.63	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
52.63	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
52.63	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
52.63	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
52.63	Consensus	endothelin_off	Orthosteric Ligand	etb_off
52.63	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
52.63	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
52.38	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
52.17	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
50.00	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
50.00	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
50.00	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
50.00	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
50.00	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
50.00	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
50.00	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
50.00	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
50.00	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
50.00	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
50.00	Single	5X93	K-8794	5X93-ET_B-K-8794
50.00	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
50.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
50.00	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
50.00	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
50.00	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
50.00	Single	6PT3	DPI-287	6PT3-δ-DPI-287
50.00	Single	6TPG	EMPA	6TPG-OX₂-EMPA
50.00	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
50.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
50.00	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
50.00	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
50.00	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
50.00	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
50.00	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
50.00	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
50.00	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
50.00	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
50.00	Single	8E0G	BU72	8E0G-μ-BU72
50.00	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
50.00	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
50.00	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
50.00	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
50.00	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
50.00	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
50.00	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
50.00	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
50.00	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
50.00	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
50.00	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
50.00	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
50.00	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
50.00	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
50.00	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
50.00	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
50.00	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
50.00	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
47.62	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
47.37	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
47.37	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
47.37	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
47.37	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
47.37	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
47.37	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
47.06	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
47.06	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
47.06	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
47.06	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
47.06	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
47.06	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
47.06	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
47.06	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
47.06	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
47.06	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
47.06	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
47.06	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
47.06	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
47.06	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
47.06	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
47.06	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
47.06	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
47.06	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
47.06	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
46.67	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
46.67	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
46.67	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
46.67	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.67	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.67	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
46.67	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
46.67	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
46.67	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
46.67	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
46.67	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
46.67	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
46.67	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
46.67	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
46.67	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
45.45	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
45.00	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
45.00	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
45.00	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
45.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
45.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
45.00	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
45.00	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
45.00	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
45.00	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
45.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
45.00	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
45.00	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
44.44	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
44.44	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
44.44	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
44.44	Single	5WQC	EMPA	5WQC-OX₂-EMPA
44.44	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
44.44	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
44.44	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
44.44	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
44.44	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
44.44	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
44.44	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
44.44	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
44.44	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
44.44	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
44.44	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.44	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
44.44	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
44.44	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
44.44	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
44.00	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
43.75	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
43.75	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
43.75	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
43.75	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
43.75	Single	6AKX	A4R	6AKX-CCR5-A4R
43.75	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
43.75	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
43.75	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
43.75	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
43.75	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
43.75	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
43.75	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
43.75	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
43.75	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
43.75	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
43.75	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
43.75	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
43.75	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
43.75	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
43.75	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
43.75	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
43.75	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
43.48	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
43.48	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
42.86	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
42.86	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
42.86	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
42.86	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
42.86	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
42.86	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
42.86	Consensus	sensory_on	Orthosteric Ligand	opsin_on
42.11	Single	4DJH	JDTic	4DJH-κ-JDTic
42.11	Single	6E59	L-760735	6E59-NK₁-L-760735
42.11	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
42.11	Single	7EPE	NAM563	7EPE-mGlu-NAM563
42.11	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
42.11	Single	7W41	PD176252	7W41-BB₂-PD176252
42.11	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
42.11	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
42.11	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
42.11	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
42.11	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
42.11	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
42.11	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
42.11	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
42.11	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
42.11	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
42.11	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
41.67	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.18	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
41.18	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
41.18	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
41.18	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
41.18	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
41.18	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
41.18	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
41.18	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
41.18	Single	6VI4	JDTic	6VI4-κ-JDTic
41.18	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
41.18	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
41.18	Single	7T32	ZM241385	7T32-A_2A-ZM241385
41.18	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
41.18	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
41.18	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
41.18	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
41.18	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
41.18	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
41.18	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.18	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
41.18	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
41.18	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
41.18	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
41.18	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
41.18	Consensus	sensory_off	Orthosteric Ligand	opsin_off
40.91	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
40.91	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.91	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
40.91	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
40.00	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
40.00	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
40.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
40.00	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
40.00	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
40.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
40.00	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
40.00	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
40.00	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
40.00	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
40.00	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
40.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
40.00	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
40.00	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
40.00	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
40.00	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
40.00	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
40.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
40.00	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
40.00	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
40.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
40.00	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
40.00	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
40.00	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
40.00	Consensus	gi_class-f	Other Ligand	gi_frizzled
40.00	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
40.00	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
40.00	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
40.00	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
40.00	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
40.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
40.00	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
39.29	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
39.29	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
39.13	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
39.13	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
38.89	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
38.89	Single	3EML	ZM241385	3EML-A_2A-ZM241385
38.89	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
38.89	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
38.89	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
38.89	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
38.89	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
38.89	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
38.89	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
38.89	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
38.89	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
38.89	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
38.89	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
38.89	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
38.89	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
38.89	Consensus	a2_off	Orthosteric Ligand	a2a_off
38.89	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
38.89	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
38.89	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
38.89	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
38.10	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
38.10	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
38.10	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
38.10	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
38.10	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
38.10	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
38.10	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
38.10	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
38.10	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
38.10	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
38.10	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
38.10	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
37.50	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
37.50	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
37.50	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
37.50	Single	6HLL	CP99994	6HLL-NK₁-CP99994
37.50	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
37.50	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
37.50	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
37.50	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
37.50	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
37.50	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
37.50	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
37.50	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
37.50	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
37.50	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
37.50	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
37.50	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
37.50	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
37.04	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
36.84	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
36.84	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
36.84	Single	5N2S	PSB36	5N2S-A₁-PSB36
36.84	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
36.84	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
36.84	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
36.84	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
36.84	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
36.84	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
36.84	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
36.84	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
36.84	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
36.84	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
36.84	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
36.84	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
36.84	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
36.84	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
36.84	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
36.84	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
36.84	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
36.84	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
36.36	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
36.36	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
36.36	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
36.36	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
36.36	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
36.36	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
36.36	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
36.36	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
36.36	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
36.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
36.00	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
36.00	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
36.00	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
35.71	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
35.71	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
35.71	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
35.71	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
35.71	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
35.71	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
35.29	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
35.29	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
35.29	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
35.29	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
35.29	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
35.29	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
35.29	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
35.29	Single	5WS3	EMPA	5WS3-OX₂-EMPA
35.29	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
35.29	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
35.29	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
35.29	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
35.29	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
35.29	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
35.29	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
35.29	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
35.29	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
35.29	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
35.29	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
35.29	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
35.29	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
35.00	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
35.00	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
35.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
35.00	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
35.00	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
35.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
35.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
35.00	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
35.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
35.00	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
35.00	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
35.00	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
35.00	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.00	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
35.00	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
35.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
35.00	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
35.00	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
35.00	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
35.00	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
35.00	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.00	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
35.00	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
35.00	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
34.78	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
34.78	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
34.78	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
34.78	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
34.78	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
34.62	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
34.62	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.62	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
34.48	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
33.33	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
33.33	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
33.33	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
33.33	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
33.33	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
33.33	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
33.33	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
33.33	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
33.33	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
33.33	Single	6IQL	L745870	6IQL-D₄-L745870
33.33	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
33.33	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
33.33	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
33.33	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
33.33	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
33.33	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
33.33	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
33.33	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
33.33	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
33.33	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
33.33	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
33.33	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
33.33	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
33.33	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
33.33	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
33.33	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
33.33	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
33.33	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
33.33	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
33.33	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
33.33	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
33.33	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
33.33	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
33.33	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
33.33	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
33.33	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
33.33	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
33.33	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
33.33	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
33.33	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
33.33	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
33.33	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
33.33	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
33.33	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
33.33	Consensus	blt_off	Orthosteric Ligand	blt1_off
33.33	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
33.33	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
33.33	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
33.33	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
33.33	Consensus	hcar_on	Orthosteric Ligand	hca_on
33.33	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
33.33	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
33.33	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
32.14	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.14	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
32.14	Consensus	go_class-b1	Orthosteric Ligand	go_crf
32.14	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
32.00	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
32.00	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
32.00	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
32.00	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
31.82	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
31.82	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
31.82	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
31.82	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
31.82	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
31.82	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
31.82	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
31.82	Consensus	orexin_on	Orthosteric Ligand	ox2_on
31.58	Single	5UEN	DU172	5UEN-A₁-DU172
31.58	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
31.58	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
31.58	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
31.58	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
31.58	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
31.58	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
31.58	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
31.58	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
31.58	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
31.58	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
31.58	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
31.58	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
31.58	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
31.58	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
31.58	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
31.58	Consensus	blt_on	Orthosteric Ligand	blt1_on
31.58	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
31.58	Consensus	leuko_on	Orthosteric Ligand	blt_on
31.58	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
31.25	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
31.25	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
31.25	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
31.25	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
31.25	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
31.03	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
31.03	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
31.03	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
31.03	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.03	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
30.77	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
30.77	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
30.77	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
30.77	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
30.77	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
30.77	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
30.77	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
30.43	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
30.43	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.43	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
30.43	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
30.43	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
30.43	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
30.43	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
30.00	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
30.00	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
30.00	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
30.00	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
30.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
30.00	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
30.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
30.00	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
30.00	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
30.00	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
30.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
30.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
30.00	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
30.00	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
29.63	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
29.63	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
29.63	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.63	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.41	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
29.41	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
29.41	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
29.41	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
29.41	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
29.41	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
29.41	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
29.41	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
29.41	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
29.41	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
29.41	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
29.41	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
29.41	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
29.17	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
29.17	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
29.17	Single	7QA8	Peptide	7QA8-STE2-Peptide
29.17	Single	7QA8	Peptide	7QA8-STE2-Peptide
29.17	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
29.17	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
29.17	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
29.17	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
29.17	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
29.17	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
29.17	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
29.17	Consensus	class-d_off	Orthosteric Ligand	ste2_off
29.17	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
29.17	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
29.17	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
29.03	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
28.57	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
28.57	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
28.57	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
28.57	Single	5XR8	AM841	5XR8-CB₁-AM841
28.57	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
28.57	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
28.57	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
28.57	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
28.57	Single	7P2L	4YI	7P2L-mGlu₅-4YI
28.57	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
28.57	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
28.57	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
28.57	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
28.57	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
28.57	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
28.57	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
28.57	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
28.57	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
28.57	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
28.57	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
28.57	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
28.57	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
28.57	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
28.57	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
28.57	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
28.12	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
28.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
28.00	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
28.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
28.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
28.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
28.00	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
28.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
28.00	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
27.78	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
27.78	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
27.78	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
27.78	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
27.78	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
27.78	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
27.78	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
27.78	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
27.78	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
27.78	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
27.78	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
27.78	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
27.78	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
27.78	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
27.78	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.59	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
27.59	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
27.59	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
27.27	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
27.27	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
27.27	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
27.27	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.27	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
27.27	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
27.27	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
27.27	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
27.27	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
27.27	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
27.27	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
27.27	Consensus	dp_off	Orthosteric Ligand	dp2_off
27.27	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
27.27	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
27.27	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
27.27	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
27.27	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
26.92	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
26.92	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
26.92	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
26.92	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
26.92	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
26.67	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
26.67	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
26.67	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
26.67	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
26.67	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
26.67	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
26.67	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
26.32	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
26.32	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
26.32	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
26.32	Single	6TPK	Retosiban	6TPK-OT-Retosiban
26.32	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
26.32	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
26.32	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
26.32	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
26.32	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
26.32	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
26.32	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
26.32	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.32	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
26.32	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
26.32	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
26.32	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
26.32	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
26.09	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
26.09	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
26.09	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
26.09	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
26.09	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
26.09	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
26.09	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
26.09	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
26.09	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
26.09	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
26.09	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
26.09	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
25.93	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
25.93	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
25.93	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.93	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
25.93	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
25.93	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
25.81	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
25.00	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
25.00	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
25.00	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
25.00	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
25.00	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
25.00	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
25.00	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
25.00	Single	6IIV	Daltroban	6IIV-TP-Daltroban
25.00	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
25.00	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
25.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
25.00	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
25.00	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
25.00	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
25.00	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
25.00	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
25.00	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
25.00	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
25.00	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
25.00	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
25.00	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
25.00	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
25.00	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
25.00	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
25.00	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
25.00	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
25.00	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
25.00	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
25.00	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
25.00	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
25.00	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
25.00	Consensus	class-d_off	Orthosteric Ligand	ste2_off
25.00	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
25.00	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
25.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
25.00	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
25.00	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
25.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
25.00	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
25.00	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
25.00	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
25.00	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
24.14	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
24.14	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
24.14	Consensus	class-d_on	Orthosteric Ligand	ste2_on
24.14	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
24.14	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
24.14	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
24.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
24.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
23.81	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
23.81	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
23.81	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
23.81	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
23.81	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
23.81	Single	7C4S	S1P	7C4S-S1P₃-S1P
23.81	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
23.81	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
23.81	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
23.81	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.81	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.81	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
23.81	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
23.81	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
23.81	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
23.81	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
23.81	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
23.81	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
23.81	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.81	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
23.53	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
23.53	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
23.53	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
23.53	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
23.53	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
23.53	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
23.53	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
23.33	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
23.33	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
23.33	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
23.33	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
23.33	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
23.33	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
23.33	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
23.08	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
23.08	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
23.08	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
22.86	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
22.86	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
22.73	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
22.73	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
22.73	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
22.73	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
22.73	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
22.73	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
22.73	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
22.73	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
22.73	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
22.73	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
22.73	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
22.73	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
22.73	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
22.73	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
22.58	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
22.58	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
22.58	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
22.58	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
22.58	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
22.22	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
22.22	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
22.22	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
22.22	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
22.22	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
22.22	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
22.22	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
22.22	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
22.22	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
22.22	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
21.74	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
21.74	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
21.74	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
21.74	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
21.74	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
21.74	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
21.74	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
21.74	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.74	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
21.74	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
21.74	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
21.74	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
21.74	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
21.74	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
21.74	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
21.62	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
21.43	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
21.43	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
21.43	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
21.43	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
21.43	Consensus	class-d_on	Orthosteric Ligand	ste2_on
21.43	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
21.43	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
21.43	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
21.43	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
21.21	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
21.21	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
21.21	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
21.05	Single	5U09	Taranabant	5U09-CB₁-Taranabant
21.05	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
21.05	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
21.05	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
21.05	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
21.05	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
21.05	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
21.05	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
21.05	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
21.05	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
21.05	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
21.05	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
21.05	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
20.83	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
20.83	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
20.83	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
20.83	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
20.83	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.83	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.83	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
20.69	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
20.69	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
20.69	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
20.69	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
20.69	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
20.69	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
20.69	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
20.69	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
20.59	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
20.59	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
20.59	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
20.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
20.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
20.00	Single	6FJ3	PTH	6FJ3-PTH1-PTH
20.00	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
20.00	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
20.00	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
20.00	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
20.00	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
20.00	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
20.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
20.00	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
20.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
20.00	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
20.00	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
20.00	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
20.00	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
20.00	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
20.00	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
20.00	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
20.00	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
20.00	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
20.00	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
20.00	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
20.00	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
20.00	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
20.00	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
20.00	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
20.00	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
20.00	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
19.44	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
19.35	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
19.35	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
19.35	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
19.35	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
19.35	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
19.35	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
19.35	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
19.23	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
19.23	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
19.23	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.23	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
19.23	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
19.23	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
19.05	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
19.05	Single	6D27	CAY10471	6D27-DP₂-CAY10471
19.05	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
19.05	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
19.05	Single	6GPS	MK0812	6GPS-CCR2-MK0812
19.05	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
19.05	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
19.05	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
19.05	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
19.05	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
19.05	Consensus	cck_off	Orthosteric Ligand	ccka_off
19.05	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
19.05	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
19.05	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
19.05	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
18.75	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
18.75	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
18.75	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
18.75	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
18.75	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
18.75	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
18.75	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
18.52	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
18.52	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
18.52	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
18.52	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
18.52	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
18.52	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
18.42	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
18.18	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
18.18	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
18.18	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
18.18	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
18.18	Single	6GPX	MK0812	6GPX-CCR2-MK0812
18.18	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
18.18	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
18.18	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
18.18	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
18.18	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
18.18	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
18.18	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
18.18	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
18.18	Consensus	ep_off	Orthosteric Ligand	ep4_off
17.86	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
17.86	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
17.86	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
17.86	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
17.86	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
17.86	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
17.86	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
17.65	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
17.65	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
17.65	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
17.65	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
17.65	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
17.39	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
17.39	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
17.39	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
17.39	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.39	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
17.39	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
17.39	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
17.39	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
17.39	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
17.39	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
17.24	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
17.24	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
17.24	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
17.24	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
17.24	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
17.24	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.24	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
17.14	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
17.07	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
16.67	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
16.67	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
16.67	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
16.67	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
16.67	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
16.67	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
16.67	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
16.67	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
16.67	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
16.67	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
16.67	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
16.67	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
16.67	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
16.67	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
16.67	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
16.67	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.13	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
16.13	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
16.13	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
16.13	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
16.13	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
16.13	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
16.13	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
16.13	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
16.13	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
16.13	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
16.13	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
16.00	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
16.00	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
16.00	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
16.00	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
16.00	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
16.00	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
16.00	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
16.00	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
16.00	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
15.79	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
15.79	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
15.79	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
15.79	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
15.62	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
15.62	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
15.62	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
15.62	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
15.62	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
15.38	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
15.38	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.38	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
15.38	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
15.38	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
15.38	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
15.38	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
15.38	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
15.38	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.38	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
15.15	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
15.15	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
15.15	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
15.15	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
15.15	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
15.15	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
15.00	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
15.00	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
15.00	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
15.00	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
15.00	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
15.00	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
15.00	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
15.00	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
15.00	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
15.00	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
15.00	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
14.81	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
14.81	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
14.81	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
14.81	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
14.81	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
14.81	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.81	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
14.71	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
14.71	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
14.71	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
14.63	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
14.29	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
14.29	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
14.29	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
14.29	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
14.29	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
14.29	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
14.29	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
14.29	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
14.29	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
13.89	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
13.79	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
13.79	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
13.79	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
13.79	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.79	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.79	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
13.79	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
13.64	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
13.64	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
13.64	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
13.64	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
13.64	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
13.64	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
13.64	Consensus	hcar_off	Orthosteric Ligand	succinate_off
13.64	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
13.64	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
13.51	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
13.33	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
13.33	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
13.33	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
13.33	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
13.33	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
13.33	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
13.16	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
13.04	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
13.04	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
13.04	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
13.04	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
13.04	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
13.04	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
13.04	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
13.04	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
12.90	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
12.90	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.50	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
12.50	Single	5V56	TC114	5V56-SMO-TC114
12.50	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
12.50	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
12.50	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
12.50	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
12.50	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
12.50	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
12.50	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
12.50	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
12.12	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
12.00	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
12.00	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
12.00	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
12.00	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
12.00	Single	6OS2	TRV026	6OS2-AT₁-TRV026
12.00	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
12.00	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
12.00	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
12.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
12.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
11.76	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
11.76	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
11.76	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
11.54	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
11.54	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
11.54	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
11.11	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.11	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
11.11	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
11.11	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
11.11	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
11.11	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
11.11	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.71	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
10.71	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
10.71	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
10.71	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
10.53	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
10.53	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
10.53	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
10.53	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
10.53	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
10.53	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
10.53	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
10.34	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
10.34	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
10.34	Consensus	sst_off	Orthosteric Ligand	sst2_off
10.00	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
10.00	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.00	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
10.00	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
10.00	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.00	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
10.00	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
10.00	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
10.00	Consensus	class-t_on	Orthosteric Ligand	taste2_on
10.00	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
10.00	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
10.00	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
10.00	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
9.52	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
9.52	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
9.52	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
9.52	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
9.52	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
9.52	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
9.52	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
9.52	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
9.52	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
9.52	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
9.09	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
9.09	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
9.09	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
9.09	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
9.09	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
9.09	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
9.09	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
9.09	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.09	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
9.09	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
9.09	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
8.82	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
8.82	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
8.70	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
8.70	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
8.70	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.57	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
8.57	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
8.33	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
8.33	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
8.33	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
8.33	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
8.00	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
8.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
8.00	Single	5V57	TC114	5V57-SMO-TC114
8.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
8.00	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
8.00	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
8.00	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
8.00	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
8.00	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
8.00	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.00	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
8.00	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
7.69	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
7.69	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
7.69	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
7.69	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
7.69	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
7.69	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
7.69	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
7.69	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
7.69	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
7.69	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
7.69	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
7.69	Consensus	nts_off	Orthosteric Ligand	nts1_off
7.69	Consensus	nts_on	Orthosteric Ligand	nts1_on
7.41	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
7.41	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
7.41	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
7.41	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
7.41	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
7.41	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.41	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
7.41	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.32	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
7.14	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
7.14	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
6.90	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
6.67	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
6.67	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
6.67	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.67	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
5.88	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
5.88	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
5.56	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
5.26	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
5.26	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
5.26	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
5.00	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
5.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.00	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
5.00	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
5.00	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
5.00	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
5.00	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
4.76	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
4.76	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
4.76	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
4.76	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
4.76	Consensus	go_protein	Orthosteric Ligand	go_chemokine
4.76	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
4.55	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
4.55	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
4.55	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
4.55	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
4.55	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
4.55	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
4.55	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
4.55	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
4.55	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.55	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
4.55	Consensus	class-f_off	Orthosteric Ligand	smo_off
4.44	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
4.35	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.35	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
4.35	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
4.35	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.35	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
4.35	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
4.35	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.35	Single	8IYX	YL-365	8IYX-GPR34-YL-365
4.35	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
4.35	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.35	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
4.17	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
4.17	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
4.17	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
4.17	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
4.17	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
4.17	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
4.17	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
4.17	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
4.17	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
4.17	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
4.17	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
4.00	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.00	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
3.85	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
3.70	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
3.70	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
3.70	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.70	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
3.70	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
3.70	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
3.70	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.57	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
3.57	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
3.33	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
3.23	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
2.70	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
2.63	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
2.63	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
2.63	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
2.56	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
2.50	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
2.50	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.44	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
2.44	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
2.33	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.17	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
2.08	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2

Consensus Members
	Id	Members
	gs_5ht	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
	gs_adrenergic	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
	gs_dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
	gs_histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
	gs_muscarinic	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
	gs_tar	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2

Net Summary
I_min	2.92876
Number of Linked Nodes	1076
Number of Links	1238
Number of Hubs	183
Number of Links mediated by Hubs	726
Number of Communities	26
Number of Nodes involved in Communities	204
Number of Links involved in Communities	284

Path Summary
Number Of Nodes in MetaPath	123
Number Of Links MetaPath	122
Number of Shortest Paths	17669991
Length Of Smallest Path	3
Average Path Length	58.178
Length of Longest Path	78
Minimum Path Strength	0.375227
Average Path Strength	7.12772
Maximum Path Strength	20.3736
Minimum Path Correlation	0.702191
Average Path Correlation	1
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.33333
Average % Of Corr. Nodes	18.2382
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	61.7815
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gs_class-a	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid

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