psnGPCRdb

GProteins → Single PSN

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Show: Click this button to access the corresponding database entry page.

PDB: PDB code of the receptor used to compute the network and a direct link to the corresponding entry in the Protein Data Bank.

Class: Receptor Class.

SubFamily: Receptor Sub Family.

Type: Receptor Type.

Subtype: Receptor SubType.

Species: Organism.

Orthosteric Ligand: Name of the orthosteric ligand, if present.

Other Ligand(s): Name of other allosteric ligands, if present.

Protein Partners: G Protein, Arrestin or Kinase coupled to a given receptor.

Resolution: Structure resolution.

Date: Deposition date.

DOI: DOI and link of the corresponding paper.


ShowPDBClassSubFamilyTypeSubTypeSpeciesOrthosteric LigandOther Ligand(s)Protein PartnersResolutionDateDOI
2X72ASensoryOpsinsRhodopsinBos taurusAll-trans-retinal-Gt(CT)32011-03-1610.1038/nature09795
3DQBASensoryOpsinsRhodopsinBos taurus--Gt(CT)3.22008-09-2310.1038/nature07330
3PQRASensoryOpsinsRhodopsinBos taurusAll-trans-retinal-Gt(CT)2.852011-03-0910.1038/nature09789
3SN6AAmineAdrenergicβ2Homo sapiensBI167107-Gs/&β;1/&γ;23.22011-07-2010.1038/nature10361
4A4MASensoryOpsinsRhodopsinBos taurusAll-trans-retinal-Gt(CT)3.32012-01-2510.1073/pnas.1114089108
4BEYASensoryOpsinsRhodopsinBos taurus--Gt(CT)2.92013-05-0810.1038/embor.2013.44
4J4QASensoryOpsinsRhodopsinBos taurusOctyl Beta-D-Glucopyranoside-Gt(CT)2.652013-10-3010.1002/anie.201302374
4X1HASensoryOpsinsRhodopsinBos taurusNonyl Beta-D-Glucopyranoside-Gt(CT)2.292015-11-0410.1016/j.str.2015.09.015
5G53ANucleotideAdenosineA2AHomo sapiensNECA-Gs3.42016-08-0310.1038/nature18966
5UZ7B1PeptideCalcitoninCTHomo sapiens--Gs/&β;1/&γ;24.12017-05-0310.1038/nature22327
5VAIB1PeptideGlucagonGLP-1Oryctolagus cuniculusGLP-1-Gs/&β;1/&γ;24.12017-05-2410.1038/nature22394
5WKTASensoryOpsinsRhodopsinBos taurusOctyl Beta-D-Glucopyranoside-Gt(CT)3.22017-12-1310.1038/nprot.2017.135
6B3JB1PeptideGlucagonGLP-1Homo sapiensExendin-P5-Gs/&β;1/&γ;23.32018-02-2110.1038/nature25773
6CMOASensoryOpsinsRhodopsinHomo sapiens--Gi1/&β;1/&γ;24.52018-06-2010.1038/s41586-018-0215-y
6D9HANucleotideAdenosineA1Homo sapiensAdenosine-Gi2/&β;1/&γ;23.62018-06-2010.1038/s41586-018-0236-6
6DDEAPeptideOpioidμMus musculusDamgo-Gi1/&β;1/&γ;23.52018-06-1310.1038/s41586-018-0219-7
6DDFAPeptideOpioidμMus musculusDamgo-Gi1/&β;1/&γ;23.52018-06-1310.1038/s41586-018-0219-7
6E3YB1PeptideCalcitoninCT LikeHomo sapiensCalcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP13.32018-09-1910.1038/s41586-018-0535-y
6E67AAmineAdrenergicβ2Homo sapiensBI167107-Gs (fused)3.72019-06-0510.1016/j.cell.2019.04.021
6FUFASensoryOpsinsRhodopsinBos taurusAll-trans-retinal-chim(Gs-Go)/&β;1/&γ;23.122018-10-0310.1126/sciadv.aat7052
6G79AAmine5-Hydroxytryptamine5-HT1BHomo sapiensDonitriptan-Go/&β;1/&γ;23.782018-06-2010.1038/s41586-018-0241-9
6GDGANucleotideAdenosineA2AHomo sapiensNECA-Gs/&β;1/&γ;14.112018-05-1610.7554/eLife.35946
6K41AAmineAdrenergicα2bHomo sapiensDexmedetomidine-Go/&β;1/&γ;22.92020-04-1510.1038/s41589-020-0492-2
6K42AAmineAdrenergicα2bHomo sapiensDexmedetomidine-Gi1/&β;1/&γ;24.12020-04-1510.1038/s41589-020-0492-2
6KPFALipidCannabinoidCB2Homo sapiensPubChem 145915889-Gi1/&β;1/&γ;22.92020-02-1210.1016/j.cell.2020.01.008
6KPGALipidCannabinoidCB1Homo sapiensAM841-Gi1/&β;1/&γ;232020-02-1210.1016/j.cell.2020.01.008
6LFMAProteinChemokineCXCR2Homo sapiensInterleukin-8-Gi1/&β;1/&γ;23.52020-09-0210.1038/s41586-020-2492-5
6LFOAProteinChemokineCXCR2Homo sapiensInterleukin-8-Gi1/&β;1/&γ;23.42020-09-0210.1038/s41586-020-2492-5
6LI3AOrphanA orphansGPR52Homo sapiens--Gs/&β;1/&γ;23.322020-02-2610.1038/s41586-020-2019-0
6LMKB1PeptideGlucagonGlucagonHomo sapiensGlucagon-Gs/&β;1/&γ;23.72020-04-0110.1126/science.aaz5346
6LPBB1PeptideVIP and PACAPPAC1Homo sapiensPACAP-Gs/&β;1/&γ;13.92020-03-1110.1038/s41594-020-0386-8
6M1HB1PeptideVIP and PACAPPAC1Homo sapiensMaxadilan-Gs/&β;1/&γ;23.62020-03-1110.1038/s41422-020-0280-2
6M1IB1PeptideVIP and PACAPPAC1Homo sapiensPACAP-Gs/&β;1/&γ;23.52020-03-1110.1038/s41422-020-0280-2
6N4BALipidCannabinoidCB1Homo sapiensMDMB-Fubinaca-Gi1/&β;1/&γ;232019-01-3010.1016/j.cell.2018.11.040
6NBFB1PeptideParathyroid hormonePTH1Homo sapiensLong-acting PTH analog-Gs/&β;1/&γ;232019-04-1710.1126/science.aav7942
6NBHB1PeptideParathyroid hormonePTH1Homo sapiensLong-acting PTH analog-Gs/&β;1/&γ;23.52019-04-1710.1126/science.aav7942
6NBIB1PeptideParathyroid hormonePTH1Homo sapiensLong-acting PTH analog-Gs/&β;1/&γ;242019-04-1710.1126/science.aav7942
6NI3AAmineAdrenergicβ2Homo sapiensBI167107-Gs/&β;1/&γ;23.82019-11-2010.1038/s41594-019-0330-y
6NIYB1PeptideCalcitoninCTHomo sapiensAdrenomedullin-Gs/&β;1/&γ;23.342019-01-2310.1021/acsptsci.8b00056
6NWEASensoryOpsinsRhodopsinBos taurusOctyl Beta-D-Glucopyranoside-Gt(CT)2.712020-02-12To be published
6OIJAAmineAcetylcholine (muscarinic)M1Homo sapiensIperoxo-chim(Gi1-Gq)/&β;1/&γ;23.32019-05-0810.1126/science.aaw5188
6OIKAAmineAcetylcholine (muscarinic)M2Homo sapiensIperoxoLY2119620Go/&β;1/&γ;23.62019-05-0810.1126/science.aaw5188
6OMMAPeptideFormylpeptideFPR2-ALXHomo sapiensWKYMVX-Gi1/&β;1/&γ;23.172020-02-2610.1038/s41467-020-14728-9
6ORVB1PeptideGlucagonGLP-1Homo sapiens-TT-OAD2Gs/&β;1/&γ;232020-01-0810.1038/s41586-019-1902-z
6OS9APeptideNeurotensinNTS1Homo sapiensJMV449-Gi1/&β;1/&γ;232019-07-1010.1038/s41586-019-1337-6
6OSAAPeptideNeurotensinNTS1Homo sapiensJMV449-Gi1/&β;1/&γ;232019-07-1010.1038/s41586-019-1337-6
6OT0FProteinFrizzledSMOHomo sapiens-25(S)-EpoxycholesterolGi1/&β;1/&γ;23.842019-06-1210.1038/s41586-019-1286-0
6OY9ASensoryOpsinsRhodopsinBos taurusAll-trans-retinal-Gt/&β;1/&γ;13.92019-07-2410.1016/j.molcel.2019.06.007
6OYAASensoryOpsinsRhodopsinBos taurusAll-trans-retinal-Gt/&β;1/&γ;13.32019-07-2410.1016/j.molcel.2019.06.007
6P9XB1PeptideCorticotropin Releasing FactorCRF1Homo sapiensCorticoliberin-Gs/&β;1/&γ;22.912020-02-0510.1016/j.molcel.2020.01.012
6P9YB1PeptideVIP and PACAPPAC1Homo sapiensPACAP-Gs/&β;1/&γ;23.012020-02-0510.1016/j.molcel.2020.01.012
6PB0B1PeptideCorticotropin Releasing FactorCRF1Homo sapiensUrocortin-chim(Gi1-Gs)/&β;1/&γ;232020-02-1210.1016/j.molcel.2020.01.013
6PB1B1PeptideCorticotropin Releasing FactorCRF2Homo sapiensUrocortin-chim(Gi1-Gs)/&β;1/&γ;22.82020-02-1210.1016/j.molcel.2020.01.013
6PELASensoryOpsinsRhodopsinBos taurus-CitronellolGt(CT)3.192020-06-24To be published
6PGSASensoryOpsinsRhodopsinBos taurus-GeraniolGt(CT)2.92020-07-01To be published
6PH7ASensoryOpsinsRhodopsinBos taurus-NerolGt(CT)2.92020-07-01To be published
6PT0ALipidCannabinoidCB2Homo sapiensWIN 55212-2-Gi1/&β;1/&γ;23.22020-02-1210.1016/j.cell.2020.01.007
6QNOASensoryOpsinsRhodopsinBos taurusAll-trans-retinal-Gi1/&β;1/&γ;14.382019-07-1010.7554/eLife.46041
6UUNB1PeptideCalcitoninCT Like (AM1)Homo sapiensAdrenomedullin-Gs/&β;1/&γ;2; RAMP232020-03-2510.1021/acsptsci.9b00080
6UUSB1PeptideCalcitoninCT Like (AM2)Homo sapiensAdrenomedullin-Gs/&β;1/&γ;2; RAMP32.42020-04-0110.1021/acsptsci.9b00080
6UVAB1PeptideCalcitoninCT Like (AM2)Homo sapiensAdrenomedullin-2-Gs/&β;1/&γ;2; RAMP32.32020-04-0110.1021/acsptsci.9b00080
6VCBB1PeptideGlucagonGLP-1Homo sapiensGLP-1LSN3160440Gs/&β;1/&γ;23.32020-07-2210.1038/s41589-020-0589-7
6VMSAAmineDopamineD2Homo sapiensBromoergocryptine-Gi1/&β;1/&γ;23.82020-06-1710.1038/s41586-020-2379-5
6VN7B1PeptideVIP and PACAPVPAC1Homo sapiensPACAP-Gs/&β;1/&γ;23.22020-09-0210.1038/s41467-020-17933-8
6WHAAAmine5-Hydroxytryptamine5-HT2AHomo sapiensDB13948-chim(Gi1-Gs)/&β;1/&γ;23.362020-09-2310.1016/j.cell.2020.08.024
6WHCB1PeptideGlucagonGlucagonHomo sapiensGlu16 analog of GCG-Gs/&β;1/&γ;23.42020-05-2710.1074/jbc.RA120.013793
6WI9B1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/&β;1/&γ;24.32020-08-1210.1038/s41467-020-17791-4
6WPWB1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-Gs/&β;1/&γ;23.12020-08-1210.1126/science.aba3373
6WWZAProteinChemokineCCR6Homo sapiensCCL20-Go/&β;1/&γ;23.342020-06-2410.1038/s41467-020-16820-6
6WZGB1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/&β;1/&γ;22.32020-08-1210.1038/s41467-020-17791-4
6X18B1PeptideGlucagonGLP-1Homo sapiensGLP-1-Gs/&β;1/&γ;22.12020-09-0910.1016/j.molcel.2020.09.020
6X19B1PeptideGlucagonGLP-1Homo sapiensCHU-128-Gs/&β;1/&γ;22.12020-09-0910.1016/j.molcel.2020.09.020
6X1AB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/&β;1/&γ;22.52020-09-0910.1016/j.molcel.2020.09.020
6XBJFProteinFrizzledSMOHomo sapiens-CholesterolGi1/&β;1/&γ;23.882020-09-3010.1038/s41589-020-0646-2
6XBKFProteinFrizzledSMOHomo sapiens-CholesterolGi1/&β;1/&γ;23.242020-09-3010.1038/s41589-020-0646-2
6XBLFProteinFrizzledSMOHomo sapiensSAGCholesterolGi1/&β;1/&γ;23.962020-09-3010.1038/s41589-020-0646-2
6XBMFProteinFrizzledSMOHomo sapiens-25(S)-EpoxycholesterolGi1/&β;1/&γ;23.142020-09-3010.1038/s41589-020-0646-2
6XOXB1PeptideGlucagonGLP-1Homo sapiensOrforglipron-chim(Gi1-Gs)/&β;1/&γ;23.12020-11-1810.1073/pnas.2014879117
7AD3D1Ste2-likeSTE2STE2Saccharomyces cerevisiaeAlpha-factor mating pheromone-Gi1/STE4/&γ;23.32020-12-0910.1038/s41586-020-2994-1
7AUEAPeptideMelanocortinMC4Homo sapiensSetmelanotide-chim(Gi1-Gs)/&β;1/&γ;22.972021-04-2810.1126/science.abf7958
7BB6APeptideVasopressin and oxytocinV2Homo sapiensAcyclovir triphosphate-Gs/&β;1/&γ;24.22021-06-0210.1126/sciadv.abg5628
7BB7APeptideVasopressin and oxytocinV2Homo sapiensAcyclovir triphosphate-Gs/&β;1/&γ;24.42021-06-0210.1126/sciadv.abg5628
7BW0ASteroidBile acidGPBAHomo sapiens--Gs/&β;1/&γ;23.92020-09-0210.1038/s41392-020-00262-z
7BZ2AAmineAdrenergicβ2Homo sapiensArformoterol-Gs/&β;1/&γ;23.822020-08-0510.1038/s41421-020-0176-9
7C2EB1PeptideGlucagonGLP-1Homo sapiensPubChem 149050799-Gs/&β;1/&γ;24.22020-08-2610.1038/s41422-020-0384-8
7CFMASteroidBile acidGPBAHomo sapiensP395-Gs/&β;1/&γ;232020-09-0910.1038/s41586-020-2569-1
7CFNASteroidBile acidGPBAHomo sapiensINT-777-Gs/&β;1/&γ;232020-09-0910.1038/s41586-020-2569-1
7CKWAAmineDopamineD1Homo sapiensFenoldopam-Gs/&β;1/&γ;23.222021-03-0310.1016/j.cell.2021.01.028
7CKXAAmineDopamineD1Homo sapiensA77636-Gs/&β;1/&γ;23.542021-03-0310.1016/j.cell.2021.01.028
7CKYAAmineDopamineD1Homo sapiensPW0464-Gs/&β;1/&γ;23.22021-03-0310.1016/j.cell.2021.01.028
7CKZAAmineDopamineD1Homo sapiensDopamineMevidalenGs/&β;1/&γ;23.12021-03-0310.1016/j.cell.2021.01.028
7CMUAAmineDopamineD3Homo sapiensPramipexole-Gi1/&β;1/&γ;232021-03-1010.1016/j.molcel.2021.01.003
7CMVAAmineDopamineD3Homo sapiensPD128907-Gi1/&β;1/&γ;22.72021-03-1010.1016/j.molcel.2021.01.003
7CRHAAmineDopamineD1Homo sapiensSKF83959-Gs/&β;1/&γ;23.32021-03-0310.1016/j.cell.2021.01.028
7CX2ALipidProstanoidEP2Homo sapiensPGE2-Gs/&β;1/&γ;22.82021-05-0510.1126/sciadv.abf1268
7CX3ALipidProstanoidEP2Homo sapiensTaprenepag-Gs/&β;1/&γ;22.82021-05-0510.1126/sciadv.abf1268
7CX4ALipidProstanoidEP2Homo sapiensEvatanepag-Gs/&β;1/&γ;22.92021-05-0510.1126/sciadv.abf1268
7CZ5B1PeptideGlucagonGHRHHomo sapiensSomatoliberin-Gs/&β;1/&γ;22.62020-11-1810.1038/s41467-020-18945-0
7D3SB1PeptideGlucagonSecretinHomo sapiensSecretin-Gs/&β;1/&γ;22.92020-11-0410.1016/j.bbrc.2020.08.042
7D68B1PeptideGlucagonGLP-2Homo sapiensGLP-2-Gs/&β;1/&γ;232020-12-1610.1038/s41422-020-00442-0
7D76B2AdhesionAdhesionADGRG3Homo sapiensBeclomethasone-Go/&β;1/&γ;23.12021-02-0310.1038/s41586-020-03083-w
7D77B2AdhesionAdhesionADGRG3Homo sapiensHydrocortisone-Go/&β;1/&γ;22.92021-02-0310.1038/s41586-020-03083-w
7D7MALipidProstanoidEP4Homo sapiensDinoprostone-Gs/&β;1/&γ;13.32020-11-1810.1016/j.str.2020.11.007
7DB6AMelatoninMelatoninMT1Homo sapiensRamelteon-Gi1/&β;1/&γ;23.32021-08-1810.1038/s41594-021-00634-1
7DFLAAmineHistamineH1Homo sapiensHistamine-chim(Gs-Gq)/&β;1/&γ;23.32021-03-3110.1038/s41467-021-22427-2
7DH5AAmineAdrenergicβ3Canis lupus familiarisMirabegron-Gs/&β;1/&γ;23.162021-08-0410.1016/j.molcel.2021.06.024
7DHIAAmineAdrenergicβ2Homo sapiensSalbutamol-Gs/&β;1/&γ;23.262020-12-1610.1093/nsr/nwaa284
7DHRAAmineAdrenergicβ2Homo sapiensIsoprenaline-Gs/&β;1/&γ;23.82020-12-1610.1093/nsr/nwaa284
7DTYB1PeptideGlucagonGIPHomo sapiensGIP-Gs/&β;1/&γ;22.982021-08-0410.7554/eLife.68719
7DUQB1PeptideGlucagonGLP-1Homo sapiensGLP-1PubChem 156022738Gs/&β;1/&γ;22.52021-07-1410.1038/s41467-021-24058-z
7DURB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/&β;1/&γ;23.32021-08-1110.1038/s41467-021-24058-z
7DW9APeptideVasopressin and oxytocinV2Homo sapiensAcyclovir triphosphate-chim(Gi1-Gs)/&β;1/&γ;22.62021-07-2110.1038/s41422-021-00480-2
7E14B1PeptideGlucagonGLP-1Homo sapiensOrforglipronPubChem 156022738Gs/&β;1/&γ;22.92021-07-0710.1038/s41467-021-24058-z
7E2XAAmine5-Hydroxytryptamine5-HT1AHomo sapiens--Gi1/&β;1/&γ;232021-04-1410.1038/s41586-021-03376-8
7E2YAAmine5-Hydroxytryptamine5-HT1AHomo sapiensSerotonin-Gi1/&β;1/&γ;232021-04-1410.1038/s41586-021-03376-8
7E2ZAAmine5-Hydroxytryptamine5-HT1AHomo sapiensAripiprazole-Gi1/&β;1/&γ;23.12021-04-1410.1038/s41586-021-03376-8
7E32AAmine5-Hydroxytryptamine5-HT1DHomo sapiensSerotonin-Gi1/&β;1/&γ;22.92021-04-2110.1038/s41586-021-03376-8
7E33AAmine5-Hydroxytryptamine5-HT1EHomo sapiensBRL-54443-Gi1/&β;1/&γ;22.92021-04-1410.1038/s41586-021-03376-8
7E9GCAmino acidMetabotropic glutamatemGlu2; mGlu2Homo sapiensEglumetadJNJ-40411813Gi1/&β;1/&γ;23.52021-06-2310.1038/s41586-021-03495-2
7E9HCAmino acidMetabotropic glutamatemGlu4; mGlu4Homo sapiensPhosphoserine-Gi3/&β;1/&γ;242021-06-2310.1038/s41586-021-03495-2
7EB2CAmino acidGABABGABAB1, GABAB2Homo sapiensBaclofenrac-BHFFGi1/&β;1/&γ;23.52021-05-0510.1038/s41586-021-03507-1
7EIBAPeptideBradykininBK1Homo sapiensDes-Arg10-Kallidin-chim(Gi1-Gs)/&β;1/&γ;232021-10-1310.1038/s41594-021-00645-y
7EJ0AAmineAdrenergicα2aHomo sapiensL-Norepinephrine-Go/&β;1/&γ;23.22022-04-1310.1126/sciadv.abj5347
7EJ8AAmineAdrenergicα2aHomo sapiensBrimonidine-Go/&β;1/&γ;232022-04-1310.1126/sciadv.abj5347
7EJAAAmineAdrenergicα2aHomo sapiensDexmedetomidine-Go/&β;1/&γ;23.62022-04-1310.1126/sciadv.abj5347
7EJKAAmineAdrenergicα2aHomo sapiensOxymetazoline-Go/&β;1/&γ;23.42022-04-1310.1126/sciadv.abj5347
7EJXAOrphanA orphansGPR88Homo sapiens-(1R;2R)-2-PCCAGi1/&β;1/&γ;22.42022-04-1310.1038/s41467-022-30081-5
7EO2ALipidLysophospholipid (S1P)S1P1Homo sapiensFTY720-P-Gi1/&β;1/&γ;22.892022-01-0510.1038/s41589-021-00930-3
7EO4ALipidLysophospholipid (S1P)S1P1Homo sapiensBAF312-Gi1/&β;1/&γ;22.862022-01-0510.1038/s41589-021-00930-3
7EPTB2AdhesionAdhesionADGRD1Homo sapiens--Gs/&β;1/&γ;232022-05-1110.1038/s41586-022-04619-y
7EQ1B2AdhesionAdhesionADGRG5Homo sapiens--Gs/&β;1/&γ;23.32022-05-1110.1038/s41586-022-04619-y
7EUOAPeptideFormylpeptideFPR1-ALXHomo sapiensfMLF-Gi1/&β;1/&γ;22.92022-05-2510.1038/s41467-022-32822-y
7EVMB1PeptideGlucagonGLP-1Homo sapiens-PubChem 156022738Gs/&β;1/&γ;22.52021-08-1110.1038/s41467-021-24058-z
7EVWFProteinFrizzledFZD7Homo sapiens--Gs/&β;1/&γ;23.222021-08-0410.1038/s41422-021-00525-6
7EVYALipidLysophospholipid (S1P)S1P1Homo sapiensSiponimod-Gi1/&β;1/&γ;22.982021-09-2910.1038/s41422-021-00566-x
7EVZALipidLysophospholipid (S1P)S1P1Homo sapiensCenerimod-Gi1/&β;1/&γ;23.072021-09-2910.1038/s41422-021-00566-x
7EW0ALipidLysophospholipid (S1P)S1P1Homo sapiensOzanimod-Gi1/&β;1/&γ;23.422021-09-2910.1038/s41422-021-00566-x
7EW1ALipidLysophospholipid (S1P)S1P5Homo sapiensSiponimod-Gi1/&β;1/&γ;23.42021-09-2910.1038/s41422-021-00566-x
7EW2ALipidLysophospholipid (S1P)S1P3Homo sapiensFingolimod-Gi1/&β;1/&γ;23.12021-09-2910.1038/s41422-021-00567-w
7EW3ALipidLysophospholipid (S1P)S1P3Homo sapiensS1P-Gi1/&β;1/&γ;23.12021-09-2910.1038/s41422-021-00567-w
7EW4ALipidLysophospholipid (S1P)S1P3Homo sapiensCYM5541-Gi1/&β;1/&γ;23.22021-09-2910.1038/s41422-021-00567-w
7EW7ALipidLysophospholipid (S1P)S1P1Homo sapiensPubChem 4077460-Gi1/&β;1/&γ;23.272021-09-2910.1038/s41422-021-00566-x
7EXDAAmine5-Hydroxytryptamine5-HT1FHomo sapiensLasmiditan-Gi1/&β;1/&γ;23.42021-08-0410.1038/s41422-021-00527-4
7EZHAPeptideCholecystokininCCKAHomo sapiensCholecystokinin-8-Gi1/&β;1/&γ;23.22021-08-2510.1038/s41589-021-00841-3
7EZKAPeptideCholecystokininCCKAHomo sapiensCholecystokinin-8-chim(Gi1-Gs)/&β;1/&γ;23.12021-08-2510.1038/s41589-021-00841-3
7EZMAPeptideCholecystokininCCKAHomo sapiensCholecystokinin-8-chim(Gs-Gq)/&β;1/&γ;22.92021-08-2510.1038/s41589-021-00841-3
7F0TAAmineDopamineD1Homo sapiensDopamine-Gs/&β;1/&γ;23.12022-06-1510.1126/sciadv.abo4158
7F16B1PeptideParathyroid hormonePTH2Homo sapiensTIP39-Gs/&β;1/&γ;22.82021-08-1810.1073/pnas.2101279118
7F1OAAmineDopamineD1Homo sapiensDopamineGDP; MgGs/&β;1/&γ;23.132022-06-1510.1126/sciadv.abo4158
7F1QAProteinChemokineCCR5Homo sapiensMIP-1a-Gi1/&β;1/&γ;22.92021-07-1410.1038/s41467-021-24438-5
7F1RAProteinChemokineCCR5Homo sapiens--Gi1/&β;1/&γ;232021-07-1410.1038/s41467-021-24438-5
7F1SAProteinChemokineCCR5Homo sapiens--Gi1/&β;1/&γ;22.82021-07-1410.1038/s41467-021-24438-5
7F1ZAAmineDopamineD1Homo sapiensDopamineGDPGs/&β;1/&γ;23.462022-06-1510.1126/sciadv.abo4158
7F23AAmineDopamineD1Homo sapiensDopamineGDPGs/&β;1/&γ;23.582022-06-1510.1126/sciadv.abo4158
7F24AAmineDopamineD1Homo sapiensDopamineGDPGs/&β;1/&γ;24.162022-06-1510.1126/sciadv.abo4158
7F2OAPeptideBradykininBK2Homo sapiensBradykinin-chim(Gi1-Gs)/&β;1/&γ;22.92021-10-1310.1038/s41594-021-00645-y
7F4DAPeptideMelanocortinMC1Homo sapiensAlpha-MSH-chim(Gi1-Gs)/&β;1/&γ;232021-09-0810.1038/s41422-021-00557-y
7F4FAPeptideMelanocortinMC1Homo sapiensAfamelanotide-chim(Gi1-Gs)/&β;1/&γ;22.92021-09-0810.1038/s41422-021-00557-y
7F4HAPeptideMelanocortinMC1Homo sapiensAfamelanotide-chim(Gi1-Gs)/&β;1/&γ;22.72021-09-0810.1038/s41422-021-00557-y
7F4IAPeptideMelanocortinMC1Homo sapiensSHU9119-chim(Gi1-Gs)/&β;1/&γ;23.12021-09-0810.1038/s41422-021-00557-y
7F53APeptideMelanocortinMC4Homo sapiensAlpha-MSH-Gs/&β;1/&γ;232021-11-0310.1038/s41422-021-00552-3
7F54APeptideMelanocortinMC4Homo sapiensAfamelanotide-Gs/&β;1/&γ;232021-11-0310.1038/s41422-021-00552-3
7F55APeptideMelanocortinMC4Homo sapiensBremelanotide-Gs/&β;1/&γ;23.12021-11-0310.1038/s41422-021-00552-3
7F58APeptideMelanocortinMC4Homo sapiensTHIQ-Gs/&β;1/&γ;23.12021-11-0310.1038/s41422-021-00552-3
7F6GAPeptideAngiotensinAT1Homo sapiensSAR1-AngII-Gq/&β;1/&γ;22.92023-03-2910.15252/embj.2022112940
7F6HAPeptideBradykininBK2Homo sapiensBradykinin-chim(Gs-Gq)/&β;1/&γ;22.92022-01-0510.1038/s41467-022-28399-1
7F6IAPeptideBradykininBK2Homo sapiensKallidin-Gq/&β;1/&γ;22.82022-01-0510.1038/s41467-022-28399-1
7F8VAPeptideCholecystokininCCKBHomo sapiensGastrin-17-Gi2/&β;1/&γ;23.32021-10-1310.1038/s41589-021-00866-8
7F8WAPeptideCholecystokininCCKBHomo sapiensGastrin-17-chim(Gs-Gq)/&β;1/&γ;23.12021-10-1310.1038/s41589-021-00866-8
7F9YAPeptideGhrelinGhrelinHomo sapiensGhrelin-28-chim(Gi1-Gs)/&β;1/&γ;22.92021-08-1810.1038/s41467-021-25364-2
7F9ZAPeptideGhrelinGhrelinHomo sapiensGHRP-6-chim(Gi1-Gs)/&β;1/&γ;23.22021-08-1810.1038/s41467-021-25364-2
7FIGAProteinGlycoprotein hormoneLHHomo sapienshCG-chim(Gi1-Gs)/&β;1/&γ;23.92021-09-2910.1038/s41586-021-03924-2
7FIHAProteinGlycoprotein hormoneLHHomo sapienshCGOrg43553Gs/&β;1/&γ;23.22021-09-2910.1038/s41586-021-03924-2
7FIIAProteinGlycoprotein hormoneLHHomo sapienshCG-Gs/&β;1/&γ;24.32021-09-2910.1038/s41586-021-03924-2
7FIMB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-Gs/&β;1/&γ;23.42022-03-0210.1038/s41467-022-28683-0
7FINB1PeptideGlucagonGIPHomo sapiensPeptide 20; GGL-Gs/&β;1/&γ;23.12022-02-2310.1038/s41467-022-28683-0
7FIYB1PeptideGlucagonGIPHomo sapiensTirzepatide-Gs/&β;1/&γ;23.42022-03-0210.1038/s41467-022-28683-0
7JHJAOtherUnclassifiedBILF1Human gammaherpesvirus 4--Gi1/&β;1/&γ;23.22021-07-0710.1016/j.immuni.2021.06.001
7JJOAAmineAdrenergicβ1Meleagris gallopavoIsoprenaline-Gs/&β;1/&γ;22.62020-09-0210.1016/j.molcel.2020.08.001
7JOZAAmineDopamineD1Homo sapiensVFP-Gs/&β;1/&γ;23.82021-04-1410.1038/s41467-021-23519-9
7JV5AAmineDopamineD1Homo sapiensSKF81297-Gs/&β;1/&γ;232021-02-2410.1016/j.cell.2021.01.027
7JVPAAmineDopamineD1Homo sapiensSKF83959-Gs/&β;1/&γ;22.92021-02-2410.1016/j.cell.2021.01.027
7JVQAAmineDopamineD1Homo sapiensApomorphine-Gs/&β;1/&γ;232021-02-2410.1016/j.cell.2021.01.027
7JVRAAmineDopamineD2Homo sapiensBromoergocryptine-Gi1/&β;1/&γ;22.82021-02-2410.1016/j.cell.2021.01.027
7KH0APeptideVasopressin and oxytocinV2Homo sapiensAcyclovir triphosphate-chim(Gi3-Gs)/&β;1/&γ;22.82021-05-2610.1038/s41422-021-00483-z
7KI0B1PeptideGlucagonGLP-1Homo sapiensSemaglutide-Gs/&β;1/&γ;22.52021-08-0410.1016/j.celrep.2021.109374
7KI1B1PeptideGlucagonGLP-1Homo sapiensTaspoglutide-Gs/&β;1/&γ;22.52021-08-0410.1016/j.celrep.2021.109374
7L0PAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/&β;1/&γ;14.12021-01-0610.1038/s41594-020-00554-6
7L0QAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/&β;1/&γ;14.32021-01-0610.1038/s41594-020-00554-6
7L0RAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/&β;1/&γ;14.22021-01-0610.1038/s41594-020-00554-6
7L0SAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin-Gi1/&β;1/γ14.52021-01-0610.1038/s41594-020-00554-6
7L1UAPeptideOrexinOX2Homo sapiensOrexin-chim(Gi1-Gs)/&β;1/&γ;23.22021-02-1010.1038/s41467-021-21087-6
7L1VAPeptideOrexinOX2Homo sapiensPubChem 155491009-chim(Gi1-Gs)/&β;1/&γ;232021-02-1010.1038/s41467-021-21087-6
7LCIB1PeptideGlucagonGLP-1Homo sapiensDanuglipron-Gs/&β;1/&γ;22.92021-01-2010.1016/j.str.2021.04.008
7LD3ANucleotideAdenosineA1Homo sapiensAdenosinePubChem 25263603Gi2/&β;1/&γ;23.22021-09-0810.1038/s41586-021-03897-2
7LD4ANucleotideAdenosineA1Homo sapiensAdenosine-Gi2/&β;1/&γ;23.32021-09-0810.1038/s41586-021-03897-2
7LJCAAmineDopamineD1Homo sapiensPubChem 86764103MevidalenGs/&β;1/&γ;232021-03-0310.1038/s41422-021-00482-0
7LJDAAmineDopamineD1Homo sapiensDopamineMevidalenGs/&β;1/&γ;13.22021-03-0310.1038/s41422-021-00482-0
7LLLB1PeptideGlucagonGLP-1Homo sapiensExendin-4-Gs/&β;1/&γ;23.72022-01-1210.1038/s41467-021-27760-0
7LLYB1PeptideGlucagonGLP-1Homo sapiensOxyntomodulin-Gs/&β;1/&γ;23.32022-01-1210.1038/s41467-021-27760-0
7MBXAPeptideCholecystokininCCKAHomo sapiensCholecystokinin-8-Gs/&β;1/&γ;11.952021-05-2610.1371/journal.pbio.3001295
7MBYAPeptideCholecystokininCCKAHomo sapiensCholecystokinin-8-chim(Gi1-Gs)/&β;1/&γ;22.442021-05-2610.1371/journal.pbio.3001295
7MTSCAmino acidMetabotropic glutamatemGlu2; mGlu2Homo sapiensGlutamateADX55164Gi1/&β;1/&γ;23.22021-07-0710.1038/s41586-021-03680-3
7NA7APeptideGhrelinGhrelinHomo sapiensGhrelin-27-Gi1/&β;1/&γ;22.72021-12-1510.1038/s41467-021-26735-5
7NA8APeptideGhrelinGhrelinHomo sapiensPubChem 178024-Gi1/&β;1/&γ;22.72021-12-1510.1038/s41467-021-26735-5
7O7FAProteinChemokineCCR5Homo sapiens(6P4)CCL5-Gi1/&β;1/&γ;13.152021-06-3010.1126/sciadv.abg8685
7P00APeptideTachykininNK1Homo sapiensSubstance P-chim(Gi1-Gs)/&β;1/&γ;22.712021-12-1510.1126/sciadv.abk2872
7P02APeptideTachykininNK1Homo sapiensProtachykinin-1-chim(Gi1-Gs)/&β;1/&γ;22.872021-12-1510.1126/sciadv.abk2872
7PIUAPeptideMelanocortinMC4Homo sapiensSetmelanotide-Gs/&β;1/&γ;22.582021-11-1710.1038/s41422-021-00569-8
7PIVAPeptideMelanocortinMC4Homo sapiensSetmelanotide-Gs/&β;1/&γ;22.862021-11-1710.1038/s41422-021-00569-8
7QVMAPeptideVasopressin and oxytocinOTHomo sapiensOxytocin-Go/&β;1/&γ;23.252022-08-1010.1038/s41467-022-31325-0
7RA3B1PeptideGlucagonGIPHomo sapiensGIP-chim(Gi3-Gs)/&β;1/&γ;23.242022-04-1310.1073/pnas.2116506119
7RANAAmine5-Hydroxytryptamine5-HT2AHomo sapiensPubChem 164575847-chim(Gi1-Gs)/&β;1/&γ;23.452022-07-0610.1038/s41586-022-05258-z
7RBTB1PeptideGlucagonGIPHomo sapiensTirzepatidePubChem 163183774Gs/&β;1/&γ;23.082022-04-1310.1073/pnas.2116506119
7RG9B1PeptideGlucagonGLP-1Homo sapiens--Gs/&β;1/&γ;23.22022-04-1310.1073/pnas.2116506119
7RGPB1PeptideGlucagonGLP-1Homo sapiensTirzepatide-chim(Gi3-Gs)/&β;1/&γ;22.92022-04-1310.1073/pnas.2116506119
7RKFAOtherUnclassifiedUS28Human betaherpesvirus 5FractalkineGDPchim(Gi1-G11)/&β;1/&γ;242022-01-2610.1126/sciadv.abl5442
7RKMAOtherUnclassifiedUS28Human betaherpesvirus 5Fractalkine-Gi1/&β;1/&γ;23.52022-01-2610.1126/sciadv.abl5442
7RKNAOtherUnclassifiedUS28Human betaherpesvirus 5Fractalkine-Gi1/&β;1/&γ;23.62022-01-2610.1126/sciadv.abl5442
7RKXAOtherUnclassifiedUS27Human betaherpesvirus 5--Gi1/&β;1/&γ;23.12022-01-2610.1126/sciadv.abl5442
7RMGAPeptideTachykininNK1Homo sapiensSubstance P-Gs/&β;1/&γ;132021-11-0310.1038/s41589-021-00890-8
7RMHAPeptideTachykininNK1Homo sapiensSubstance P-Gs/&β;1/&γ;23.12021-11-0310.1038/s41589-021-00890-8
7RMIAPeptideTachykininNK1Homo sapiensSubstance P-chim(Gi1-Gs)/&β;1/&γ;23.22021-11-0310.1038/s41589-021-00890-8
7RTBB1PeptideGlucagonGLP-1Homo sapiensPeptide-19-Gs/&β;1/&γ;22.142021-10-0610.1016/j.bbrc.2021.09.016
7RYCAPeptideVasopressin and oxytocinOTHomo sapiensOxytocin-chim(Gi1-Gs)/&β;1/&γ;22.92022-03-0910.1038/s41594-022-00728-4
7S0FAAmineAdrenergicβ1Meleagris gallopavoIsoprenaline-Gi1/&β;1/&γ;22.962021-11-1710.1038/s41594-021-00679-2
7S0GAAmineAdrenergicβ1Meleagris gallopavoIsoprenaline-Gi1(GsCter)/&β;1/&γ;23.862021-11-1710.1038/s41594-021-00679-2
7S1MB1PeptideGlucagonGLP-1Homo sapiensEx4-D-Ala-Gs/&β;1/&γ;22.412022-01-0510.1038/s41589-021-00945-w
7S3IB1PeptideGlucagonGLP-1Homo sapiens--Gs/&β;1/&γ;22.512022-01-0510.1038/s41589-021-00945-w
7S8LAOrphanA orphansMRGPRX2Homo sapiensCortistatin-14-chim(Gi1-Gs)/&β;1/&γ;22.452021-11-1710.1038/s41586-021-04126-6
7S8MAOrphanA orphansMRGPRX2Homo sapiensCortistatin-14-Gi1/&β;1/&γ;22.542021-11-1710.1038/s41586-021-04126-6
7S8NAOrphanA orphansMRGPRX2Homo sapiens(R)-Zinc-3573-chim(Gi1-Gs)/&β;1/&γ;22.92021-11-1710.1038/s41586-021-04126-6
7S8OAOrphanA orphansMRGPRX2Homo sapiens(R)-Zinc-3573-Gi1/&β;1/&γ;22.582021-11-1710.1038/s41586-021-04126-6
7S8PAOrphanA orphansMRGPRX4Homo sapiensMS47134-chim(Gi1-Gs)/&β;1/&γ;22.62021-11-1710.1038/s41586-021-04126-6
7SBFAPeptideOpioidμMus musculusPZM21-Gi1/&β;1/&γ;22.92022-04-2010.1002/anie.202200269
7SCGAPeptideOpioidμMus musculusFH210-Gi1/&β;1/&γ;232022-04-2010.1002/anie.202200269
7SF7B2AdhesionAdhesionADGRL3Homo sapiens--chim(Gi2-G13)/&β;1/&γ;22.92022-04-2710.1038/s41586-022-04575-7
7SF8B2AdhesionAdhesionADGRG1Homo sapiens--chim(Gi2-G13)/&β;1/&γ;22.72022-04-2710.1038/s41586-022-04575-7
7SQOAPeptideOrexinOX2Homo sapiensTAK-925-Gi1/&β;1/&γ;23.172022-05-2510.1038/s41467-022-30601-3
7SR8APeptideOrexinOX2Homo sapiensTAK-925-chim(Gi1-Gs)/&β;1/&γ;23.32022-06-0810.1038/s41467-022-30601-3
7SRRAAmine5-Hydroxytryptamine5-HT2BHomo sapiensLSD-chim(Gi1-Gs)/&β;1/&γ;22.92022-09-2110.1016/j.neuron.2022.08.006
7T2GAPeptideOpioidμMus musculusMitragynine pseudoindoxyl-Gi1/&β;1/&γ;22.52022-12-0710.1038/s41589-022-01208-y
7T2HAPeptideOpioidμMus musculusLofentanil-Gi1/&β;1/&γ;22.52022-12-0710.1038/s41589-022-01208-y
7T6BALipidLysophospholipid (S1P)S1P2Homo sapiensS1P-chim(Gi1-G13)/&β;1/&γ;23.192022-04-0610.1126/sciadv.abn0067
7T6SAPeptideFormylpeptideFPR2-ALXHomo sapiensPubChem 24776341-Gi1/&β;1/&γ;232022-03-3010.1038/s41467-022-28586-0
7T6TAPeptideFormylpeptideFPR1-ALXHomo sapiensfMLFII-Gi1/&β;1/&γ;23.22022-03-3010.1038/s41467-022-28586-0
7T6UAPeptideFormylpeptideFPR2-ALXHomo sapiensCGEN-855A-Gi1/&β;1/&γ;22.92022-03-3010.1038/s41467-022-28586-0
7T6VAPeptideFormylpeptideFPR2-ALXHomo sapiensfMLFII-Gi1/&β;1/&γ;23.12022-03-3010.1038/s41467-022-28586-0
7T8XAAmineAcetylcholine (muscarinic)M2Homo sapiensAcetylcholine-Go/&β;1/&γ;23.212023-01-25To be published
7T90AAmineAcetylcholine (muscarinic)M2Homo sapiensAcetylcholine-Go/&β;1/&γ;23.322023-01-25To be published
7T94AAmineAcetylcholine (muscarinic)M2Homo sapiensAcetylcholinePubChem 57664406Go/&β;1/&γ;23.162023-01-25To be published
7T9IAProteinGlycoprotein hormoneTSHHomo sapiensTSH-Gs/&β;1/&γ;22.92022-08-0310.1038/s41586-022-05159-1
7T9NAProteinGlycoprotein hormoneTSHHomo sapiensM22 FabPubChem 644078Gs/&β;1/&γ;22.92022-08-0310.1038/s41586-022-05159-1
7TD0ALipidLysophospholipid (LPA)LPA1Homo sapiensLPA-Gi1/&β;1/&γ;22.832022-02-0910.1038/s41467-022-28417-2
7TD1ALipidLysophospholipid (LPA)LPA1Homo sapiensLPA-Gi1/&β;1/&γ;23.082022-02-0910.1038/s41467-022-28417-2
7TD2ALipidLysophospholipid (LPA)LPA1Homo sapiensLPA-Gi1/&β;1/&γ;23.112022-02-0910.1038/s41467-022-28417-2
7TD3ALipidLysophospholipid (S1P)S1P1Homo sapiensS1P-Gi1/&β;1/&γ;232022-02-0910.1038/s41467-022-28417-2
7TD4ALipidLysophospholipid (S1P)S1P1Homo sapiensSiponimod-Gi1/&β;1/&γ;22.62022-02-0910.1038/s41467-022-28417-2
7TMWAPeptideRelaxinRXFP1Homo sapiens--Gs/&β;1/&γ;23.22023-02-1510.1101/2022.01.22.477343
7TRKAAmineAcetylcholine (muscarinic)M4Homo sapiensIperoxo-Gi1/&β;1/&γ;22.82023-05-1710.2139/ssrn.4034884
7TRPAAmineAcetylcholine (muscarinic)M4Homo sapiensIperoxoLY2033298Gi1/&β;1/&γ;22.42023-05-1710.2139/ssrn.4034884
7TRQAAmineAcetylcholine (muscarinic)M4Homo sapiensIperoxoVU0467154Gi1/&β;1/&γ;22.52023-05-1710.2139/ssrn.4034884
7TRSAAmineAcetylcholine (muscarinic)M4Homo sapiensAcetylcholine-Gi1/&β;1/&γ;22.82023-05-1710.2139/ssrn.4034884
7TRYB1PeptideCorticotropin Releasing FactorCRF2Homo sapiensUrocortin-chim(Gi1-G11)/&β;1/&γ;23.72022-11-0910.1038/s41467-022-33851-3
7TS0B1PeptideCorticotropin Releasing FactorCRF2Homo sapiensUrocortin-chim(Gi1-Go)/&β;1/&γ;22.82022-11-0910.1038/s41467-022-33851-3
7TUZAOrphanA orphansGPR183Homo sapiens7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;23.122022-04-1310.1016/j.str.2022.04.006
7TYFB1PeptideClacitoninCT (AMY1)Homo sapiensAmylin-Gs/&β;1/&γ;2; RAMP12.22022-03-2310.1126/science.abm9609
7TYHB1PeptideClacitoninCT (AMY2)Homo sapiensCalcitonin-1-Gs/&β;1/&γ;2; RAMP23.32022-03-2310.1126/science.abm9609
7TYIB1PeptideClacitoninCTHomo sapiensAmylin-Gs/&β;1/&γ;23.32022-03-3010.1126/science.abm9609
7TYLB1PeptideClacitoninCTHomo sapiensAmylin-Gs/&β;1/&γ;23.32022-03-2310.1126/science.abm9609
7TYNB1PeptideClacitoninCTHomo sapiensCalcitonin-1-Gs/&β;1/&γ;22.62022-03-3010.1126/science.abm9609
7TYOB1PeptideClacitoninCTHomo sapiensCalcitonin-Gs/&β;1/&γ;22.72022-03-2310.1126/science.abm9609
7TYWB1PeptideClacitoninCT (AMY1)Homo sapiensCalcitonin-1-Gs/&β;1/&γ;2; RAMP132022-03-2310.1126/science.abm9609
7TYXB1PeptideClacitoninCT (AMY2)Homo sapiensAmylin-Gs/&β;1/&γ;2; RAMP22.552022-03-3010.1126/science.abm9609
7TYYB1PeptideClacitoninCT (AMY2)Homo sapiensCalcitonin-1-Gs/&β;1/&γ;2; RAMP232022-03-2310.1126/science.abm9609
7TZFB1PeptideClacitoninCT (AMY3)Homo sapiensAmylin-Gs/&β;1/&γ;2; RAMP32.42022-03-2310.1126/science.abm9609
7U2KAPeptideOpioidμMus musculusC6-guano-Gi1/&β;1/&γ;23.32022-12-0710.1038/s41586-022-05588-y
7U2LAPeptideOpioidμMus musculusPubChem 163201242-Gi1/&β;1/&γ;23.22022-05-0410.1038/s41586-022-05588-y
7UM5AAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-Go/&β;1/&γ;22.732022-07-2010.1038/s41594-022-00796-6
7UM6AAmine5-Hydroxytryptamine5-HT5AHomo sapiensLisuride-Go/&β;1/&γ;22.792022-07-2010.1038/s41594-022-00796-6
7UM7AAmine5-Hydroxytryptamine5-HT5AHomo sapiensMethylergometrine-Go/&β;1/&γ;22.752022-07-2010.1038/s41594-022-00796-6
7UTZAProteinGlycoprotein hormoneTSHHomo sapiensTR1402PubChem 644078Gs/&β;1/&γ;22.42022-08-0310.1038/s41586-022-05159-1
7V35B1PeptideGlucagonGlucagonHomo sapiensPeptide-20-Gs/&β;1/&γ;23.52022-03-0210.1038/s41467-022-28683-0
7V68AAmineAcetylcholine (muscarinic)M4Homo sapiensIperoxoPubChem 57664406Gi1/&β;1/&γ;23.42022-05-1110.1038/s41467-022-30595-y
7V69AAmineAcetylcholine (muscarinic)M4Homo sapiens--Gi1/&β;1/&γ;23.42022-05-1110.1038/s41467-022-30595-y
7V6AAAmineAcetylcholine (muscarinic)M4Homo sapiensPubChem 9864275-Gi1/&β;1/&γ;23.62022-05-1110.1038/s41467-022-30595-y
7V9LB1PeptideGlucagonGHRH (SV1)Homo sapiens--Gs/&β;1/&γ;22.62022-04-0610.1073/pnas.2106606118
7V9MB1PeptideGlucagonGHRH (SV1)Homo sapiensSomatoliberin-Gs/&β;1/&γ;23.292021-10-2010.1073/pnas.2106606118
7VABB1PeptideGlucagonGIPHomo sapiensNon-Acylated Tirzepatide-chim(Gi1-Gs)/&β;1/&γ;23.22022-03-0210.1038/s41467-022-28683-0
7VBHB1PeptideGlucagonGLP-1Homo sapiensPeptide-20-Gs/&β;1/&γ;232022-04-0610.1038/s41467-022-28683-0
7VBIB1PeptideGlucagonGLP-1Homo sapiensNon-Acylated Tirzepatide-Gs/&β;1/&γ;232022-03-0210.1038/s41467-022-28683-0
7VDHAOrphanA orphansMRGPRX2Homo sapiensC48/80-Gi1/&β;1/&γ;22.92021-12-0110.1038/s41586-021-04077-y
7VDLAOrphanA orphansMRGPRX2Homo sapiensCortistatin-14-Gi1/&β;1/&γ;23.222021-12-0110.1038/s41586-021-04077-y
7VDMAOrphanA orphansMRGPRX2Homo sapiensSubstance P-Gi1/&β;1/&γ;22.982021-12-0110.1038/s41586-021-04077-y
7VFXAPeptideFormylpeptideFPR1-ALXHomo sapiensfMLF-Gi1/&β;1/&γ;22.82022-09-2110.1038/s41467-022-32822-y
7VGXAPeptideNeuropeptide YY1Homo sapiensNeuropeptide Y-Gi1/&β;1/&γ;23.22022-02-2310.1038/s41467-022-28510-6
7VGYAMelatoninMelatoninMT1Homo sapiens2-Iodomelatonin-Gi1/&β;1/&γ;23.12022-03-0210.1038/s41467-022-28111-3
7VGZAMelatoninMelatoninMT1Homo sapiensRemalteon-Gi1/&β;1/&γ;23.32022-03-0210.1038/s41467-022-28111-3
7VH0AMelatoninMelatoninMT2Homo sapiensRamelteon-Gi1/&β;1/&γ;13.462022-03-0210.1038/s41467-022-28111-3
7VIEALipidLysophospholipid (S1P)S1P1Homo sapiensS1P-Gi1/&β;1/&γ;22.862022-09-2810.1073/pnas.2117716119
7VIFALipidLysophospholipid (S1P)S1P1Homo sapiens(S)-FTY720-P-Gi1/&β;1/&γ;22.832022-09-2810.1073/pnas.2117716119
7VIGALipidLysophospholipid (S1P)S1P1Homo sapiensCBP-307-Gi1/&β;1/&γ;22.892022-09-2810.1073/pnas.2117716119
7VIHALipidLysophospholipid (S1P)S1P1Homo sapiensCBP-307-Gi1/&β;1/&γ;22.982022-09-2810.1073/pnas.2117716119
7VKTALipidLeukotrieneBLT1Homo sapiensLTB4-Gi1/&β;1/&γ;22.92022-03-0910.1038/s41467-022-28820-9
7VL8AProteinChemokineCCR1Homo sapiens--Gi1/&β;1/&γ;22.92022-03-2310.1038/s41589-021-00918-z
7VL9AProteinChemokineCCR1Homo sapiensCCL15(26-92)-Gi1/&β;1/&γ;22.62022-03-2310.1038/s41589-021-00918-z
7VLAAProteinChemokineCCR1Homo sapiensCCL15(27-92)-Gi1/&β;1/&γ;22.72022-03-2310.1038/s41589-021-00918-z
7VQXB1PeptideVIP and PACAPVPAC1Homo sapiensPACAP27-Gs/&β;1/&γ;22.742022-05-1810.1038/s41467-022-30041-z
7VUGAOrphanA orphansGPR139Homo sapiensJNJ-63533054-Gi1/&β;1/&γ;23.22021-12-2910.1038/s41422-021-00591-w
7VUHAOrphanA orphansGPR139Homo sapiensJNJ-63533054-Gs/&β;1/&γ;13.222021-12-2910.1038/s41422-021-00591-w
7VUIAOrphanA orphansGPR139Homo sapiensJNJ-63533054GTPGs/&β;1/&γ;13.32021-12-2910.1038/s41422-021-00591-w
7VUJAOrphanA orphansGPR139Homo sapiensJNJ-63533054GDPGs/&β;1/&γ;23.82021-12-2910.1038/s41422-021-00591-w
7VUYAOrphanA orphansMRGPRX2Homo sapiens--Gi1/&β;1/&γ;22.842021-12-0110.1038/s41586-021-04077-y
7VUZAOrphanA orphansMRGPRX2Homo sapiens--Gi1/&β;1/&γ;22.892021-12-0110.1038/s41586-021-04077-y
7VV3AOrphanA orphansMRGPRX2Homo sapiens--Gi1/&β;1/&γ;22.972021-12-0110.1038/s41586-021-04077-y
7VV5AOrphanA orphansMRGPRX2Homo sapiensC48/80-Gi1/&β;1/&γ;22.762021-12-0110.1038/s41586-021-04077-y
7VVJB1PeptideParathyroid hormonePTH1Homo sapiensPTHrP(1-36)-Gs/&β;1/&γ;23.22022-08-0310.1016/j.molcel.2022.07.003
7VVKB1PeptideParathyroid hormonePTH1Homo sapiensPTH-Gs/&β;1/&γ;23.32022-08-0310.1016/j.molcel.2022.07.003
7VVLB1PeptideParathyroid hormonePTH1Homo sapiensPTH-Gs/&β;1/&γ;22.82022-08-0310.1016/j.molcel.2022.07.003
7VVMB1PeptideParathyroid hormonePTH1Homo sapiensPTH-Gs/&β;1/&γ;23.22022-08-0310.1016/j.molcel.2022.07.003
7VVNB1PeptideParathyroid hormonePTH1Homo sapiensPTH-Gs/&β;1/&γ;23.82022-08-0310.1016/j.molcel.2022.07.003
7VVOB1PeptideParathyroid hormonePTH1Homo sapiensPTH-Gs/&β;1/&γ;24.12022-08-0310.1016/j.molcel.2022.07.003
7W0LAPeptideApelinApelinHomo sapiensPubChem 122701908-Gi1/&β;1/&γ;23.572022-07-2710.1038/s41594-022-00797-5
7W0MAPeptideApelinApelinHomo sapiensPubChem 122701908-Gi1/&β;1/&γ;23.712022-07-2710.1038/s41594-022-00797-5
7W0NAPeptideApelinApelinHomo sapiensElabela-Gi1/&β;1/&γ;24.212022-07-2710.1038/s41594-022-00797-5
7W0OAPeptideApelinApelinHomo sapiensElabela-Gi1/&β;1/&γ;23.782022-07-2710.1038/s41594-022-00797-5
7W0PAPeptideApelinApelinHomo sapiensElabela-Gi1/&β;1/&γ;23.162022-07-2710.1038/s41594-022-00797-5
7W2ZAPeptideGhrelinGhrelinHomo sapiensGhrelin-Go/&β;1/&γ;22.82022-01-1910.1038/s41467-022-27975-9
7W3ZAPeptideBombesinBB2Homo sapiensGastrin Releasing Peptide-chim(Gi1-Gq)/&β;1/&γ;232023-02-2210.1073/pnas.2216230120
7W40APeptideBombesinBB2Homo sapiensBombesin-chim(Gi1-Gq)/&β;1/&γ;232023-02-2210.1073/pnas.2216230120
7W53APeptideNeuromedin UNMUR1Homo sapiensNeuromedin-U-25-chim(Gi1-Gs)/&β;1/&γ;23.22022-04-2010.1038/s41467-022-29683-w
7W55APeptideNeuromedin UNMUR2Homo sapiensNeuromedin-U-25-chim(Gi1-Gs)/&β;1/&γ;22.82022-04-2010.1038/s41467-022-29683-w
7W56APeptideNeuromedin UNMUR1Homo sapiensNeuromedin-S-chim(Gi1-Gs)/&β;1/&γ;22.92022-04-2010.1038/s41467-022-29683-w
7W57APeptideNeuromedin UNMUR2Homo sapiensNeuromedin-S-chim(Gi1-Gs)/&β;1/&γ;23.22022-04-2010.1038/s41467-022-29683-w
7W6PAAmineAdrenergicα2aHomo sapiensW96-Go/&β;1/&γ;23.472022-09-2810.1126/science.abn7065
7W7EAAmineAdrenergicα2aHomo sapiensW58-Go/&β;1/&γ;23.42022-09-2810.1126/science.abn7065
7WBJB1PeptideVIP and PACAPVPAC1Homo sapiensPACAP27-Gs/&β;1/&γ;23.422022-05-1810.1038/s41467-022-30041-z
7WCMALipidGPR119GPR119Homo sapiensMBX-2982-Gs/&β;1/&γ;22.332022-12-2110.1038/s41467-022-34696-6
7WCNALipidGPR119GPR119Homo sapiensAR231453-Gs/&β;1/&γ;22.872022-12-2110.1038/s41467-022-34696-6
7WF7ALipidLysophospholipid (S1P)S1P1Homo sapiensS1P-Gi1/&β;1/&γ;23.42022-01-0510.1038/s41589-021-00930-3
7WICAPeptideSomatostatinSST2Homo sapiensSomatostatin-14-Gi1/&β;1/&γ;22.82022-06-0110.1038/s41422-022-00669-z
7WIGAPeptideSomatostatinSST2Homo sapiensL-054,264-Gi1/&β;1/&γ;22.72022-06-0110.1038/s41422-022-00669-z
7WJ5APeptideSomatostatinSST2Homo sapiensSomatostatin-14-Gi1/&β;1/&γ;23.722022-07-1310.7554/eLife.76823
7WKDAPeptideThyrotropin-releasing hormoneTRHHomo sapiensTRH-chim(Gi1-Gs)/&β;1/&γ;23.012022-06-1510.1038/s41422-022-00641-x
7WQ3APeptideGalaninGAL1Homo sapiensGalanin-Gi1/&β;1/&γ;22.72022-04-2010.1038/s41467-022-29072-3
7WQ4APeptideGalaninGAL2Homo sapiensGalanin-chim(Gi1-Gs)/&β;1/&γ;22.62022-04-2010.1038/s41467-022-29072-3
7WU2B2AdhesionAdhesionADGRD1Homo sapiens--Gs/&β;1/&γ;12.82022-04-2710.1038/s41586-022-04580-w
7WU3B2AdhesionAdhesionADGRF1Homo sapiens-K6GGs/&β;1/&γ;23.12022-04-2710.1038/s41586-022-04580-w
7WU4B2AdhesionAdhesionADGRF1Homo sapiens-K6GGi1/&β;1/&γ;23.42022-04-2710.1038/s41586-022-04580-w
7WU5B2AdhesionAdhesionADGRF1Homo sapiens-K6GGi1/&β;1/&γ;232022-04-2710.1038/s41586-022-04580-w
7WU9ALipidProstanoidEP3Homo sapiens--Gi1/&β;1/&γ;23.382022-08-1710.1016/j.celrep.2022.111323
7WUIB2AdhesionAdhesionADGRG2Mus musculusIP15-chim(Gi1-Gs)/&β;1/&γ;23.12022-04-2710.1038/s41586-022-04590-8
7WUJB2AdhesionAdhesionADGRG4Homo sapiens--chim(Gi1-Gs)/&β;1/&γ;23.32022-04-2710.1038/s41586-022-04590-8
7WUQB2AdhesionAdhesionADGRG2Mus musculus--Gs/&β;1/&γ;22.92022-04-2710.1038/s41586-022-04590-8
7WV9ALipidCannabinoidCB1Homo sapiensPubMed 104895ZCZ011Gi2/&β;1/&γ;23.362022-06-1510.1038/s41589-022-01038-y
7WVUAPeptideFormylpeptideFPR1-ALXHomo sapiensfMLF-Gi1/&β;1/&γ;23.32022-04-1310.1038/s41467-022-29361-x
7WVVAPeptideFormylpeptideFPR2-ALXHomo sapiensfMLFII-Gi1/&β;1/&γ;22.92022-04-1310.1038/s41467-022-29361-x
7WVWAPeptideFormylpeptideFPR2-ALXHomo sapiensfMYFINILTL-Gi2/&β;1/&γ;23.12022-04-1310.1038/s41467-022-29361-x
7WVXAPeptideFormylpeptideFPR2-ALXHomo sapiensHumanin-Gi2/&β;1/&γ;22.82022-04-1310.1038/s41467-022-29361-x
7WVYAPeptideFormylpeptideFPR2-ALXHomo sapiensAmyloid-Beta42-Gi2/&β;1/&γ;232022-04-1310.1038/s41467-022-29361-x
7WXUB2AdhesionAdhesionADGRF1Homo sapiens--Gs/&β;1/&γ;22.852022-09-2810.1038/s41467-022-33173-4
7WXWB2AdhesionAdhesionADGRF1Homo sapiens--chim(Gi1-Gs)/&β;1/&γ;22.842022-09-2810.1038/s41467-022-33173-4
7WY0B2AdhesionAdhesionADGRF1Homo sapiens--chim(Gi1-G13)/&β;1/&γ;22.832022-09-2810.1038/s41467-022-33173-4
7WY5B2AdhesionAdhesionADGRL3Mus musculus--chim(Gi1-Gs)/&β;1/&γ;22.832022-10-2610.1016/j.molcel.2022.10.009
7WY8B2AdhesionAdhesionADGRL3Mus musculus--chim(Gi1-Gs)/&β;1/&γ;22.832022-10-2610.1016/j.molcel.2022.10.009
7WYBB2AdhesionAdhesionADGRL3Mus musculus--Gi1/&β;1/&γ;22.972022-10-2610.1016/j.molcel.2022.10.009
7WZ4AOrphanA orphansGPR88Homo sapiens--Gi1/&β;1/&γ;232022-10-2610.1038/s41467-022-30081-5
7WZ7B2AdhesionAdhesionADGRF1Homo sapiens--chim(Gi1-G12)/&β;1/&γ;22.832022-09-2810.1038/s41467-022-33173-4
7X10B2AdhesionAdhesionADGRL3Mus musculus--chim(Gi1-G12)/&β;1/&γ;22.932022-10-2610.1016/j.molcel.2022.10.009
7X1TAPeptideThyrotropin-releasing hormoneTRHHomo sapiensTaltirelin-chim(Gi1-Gs)/&β;1/&γ;23.262022-08-3110.1038/s41422-022-00646-6
7X1UAPeptideThyrotropin-releasing hormoneTRHHomo sapiensTRH-chim(Gi1-Gs)/&β;1/&γ;23.192022-08-3110.1038/s41422-022-00646-6
7X2CAAmineDopamineD1Homo sapiensFenoldopamFenoldopamGs/&β;1/&γ;23.22022-06-2910.1038/s41467-022-30929-w
7X2DAAmineDopamineD1Homo sapiensTavapadon-Gs/&β;1/&γ;23.32022-06-1510.1038/s41467-022-30929-w
7X2FAAmineDopamineD1Homo sapiensDopamineMevidalenGs/&β;1/&γ;232022-06-1510.1038/s41467-022-30929-w
7X2VB2AdhesionAdhesionADGRF1Homo sapiens--Gi1/&β;1/&γ;23.092022-09-2810.1038/s41467-022-33173-4
7X5HAAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-Gi1/&β;1/&γ;23.12022-09-1410.1038/s41421-022-00412-3
7X8RB1PeptideGlucagonGLP-1Homo sapiensBOC5-Gs/&β;1/&γ;22.612022-06-2910.1073/pnas.2200155119
7X8SB1PeptideGlucagonGLP-1Homo sapiensWB4-24-Gs/&β;1/&γ;23.092022-06-2910.1073/pnas.2200155119
7X9AAPeptideNeuropeptide YY1Homo sapiensNeuropeptide Y-Gi1/&β;1/&γ;23.22022-05-1810.1126/sciadv.abm1232
7X9BAPeptideNeuropeptide YY2Homo sapiensNeuropeptide Y-Gi1/&β;1/&γ;23.42022-05-1810.1126/sciadv.abm1232
7X9CAPeptideNeuropeptide YY4Homo sapiensPancreatic Hormone-Gi1/&β;1/&γ;232022-05-1810.1126/sciadv.abm1232
7X9YAProteinChemokineCCR3Homo sapiens--Gi1/&β;1/&γ;23.12022-08-2410.1038/s41421-022-00403-4
7XA3AProteinChemokineCCR2Homo sapiensCCL2-Gi1/&β;1/&γ;22.92022-08-2410.1038/s41421-022-00403-4
7XATAPeptideSomatostatinSST2Homo sapiensSomatostatin-14-Gi1/&β;1/&γ;22.852022-08-3110.1038/s41421-022-00405-2
7XAUAPeptideSomatostatinSST2Homo sapiensOctreotide-Gi1/&β;1/&γ;22.972022-08-3110.1038/s41421-022-00405-2
7XAVAPeptideSomatostatinSST2Homo sapiensLanreotide-Gi1/&β;1/&γ;22.872022-08-3110.1038/s41421-022-00405-2
7XBDAPeptideGalaninGAL2Homo sapiensGalanin-chim(Gi1-Gs)/&β;1/&γ;23.112022-07-1310.1371/journal.pbio.3001714
7XBWAProteinChemokineCX3CR1Homo sapiens--Gi1/&β;1/&γ;22.82022-07-1310.1126/sciadv.abn8048
7XBXAProteinChemokineCX3CR1Homo sapiensCX3CL1-Gi1/&β;1/&γ;23.42022-07-1310.1126/sciadv.abn8048
7XJHAAmineAdrenergicβ3Canis lupus familiarisIsoproterenol-Gs/&β;1/&γ;23.32022-05-0410.1016/j.molcel.2021.06.024
7XJIAAmineAdrenergicβ3Canis lupus familiarisSolabegron-Gs/&β;1/&γ;23.92022-05-0410.1016/j.bbrc.2022.04.065
7XJJAPeptideGalaninGAL1Homo sapiensGalanin-Go/&β;1/&γ;23.32023-05-0310.1073/pnas.2121465119
7XJKAPeptideGalaninGAL2Homo sapiensGalanin-chim(Gi1-Gs)/&β;1/&γ;23.32022-06-2910.1073/pnas.2121465119
7XJLAPeptideGalaninGAL2Homo sapiensSpexin-chim(Gi1-Gs)/&β;1/&γ;23.52022-06-2910.1073/pnas.2121465119
7XK2AAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensMK6892-Gi1/&β;1/&γ;23.12023-02-2210.1038/s41467-023-37177-6
7XK8APeptideNeuromedin UNMUR2Homo sapiensNeuromedin-U-25-Gi1/&β;1/&γ;23.32023-02-2210.1038/s41467-022-34814-4
7XKDB2AdhesionAdhesionADGRG2Mus musculusBetahydroxyandrosterone-Gs/&β;1/&γ;22.42022-08-1010.1038/s41589-022-01084-6
7XKEB2AdhesionAdhesionADGRG2Mus musculusBetahydroxyandrosterone-chim(Gi1-Gs)/&β;1/&γ;22.92022-08-1010.1038/s41589-022-01084-6
7XKFB2AdhesionAdhesionADGRG2Mus musculusBetahydroxyandrosterone-Gs/&β;1/&γ;22.42022-08-1010.1038/s41589-022-01084-6
7XMRAPeptideSomatostatinSST2Homo sapiensSomatostatin-14-Gi1/&β;1/&γ;23.12022-08-0310.1038/s41422-022-00679-x
7XMSAPeptideSomatostatinSST4Homo sapiensSomatostatin-14-Gi1/&β;1/&γ;22.92022-08-0310.1038/s41422-022-00679-x
7XMTAPeptideSomatostatinSST4Homo sapiensJ-2156-Gi1/&β;1/&γ;22.82022-08-0310.1038/s41422-022-00679-x
7XOUAPeptideCholecystokininCCKAHomo sapiensCholecystokinin-8-Gs/&β;1/&γ;23.22022-07-2010.1038/s41421-022-00420-3
7XOVAPeptideCholecystokininCCKAHomo sapiensSR146131-Gs/&β;1/&γ;232022-07-2010.1038/s41421-022-00420-3
7XOWAPeptideCholecystokininCCKBHomo sapiensGastrin-Gq/&β;1/&γ;23.12022-07-2010.1038/s41421-022-00420-3
7XOXAPeptideCholecystokininCCKBHomo sapiensCholecystokinin-8-Gq/&β;1/&γ;23.12022-07-2010.1038/s41421-022-00420-3
7XP4TSensoryTaste2T2R46Homo sapiens--chim(Gt3-Gs)/&β;1/&γ;23.012022-10-1210.1126/science.abo1633
7XP5TSensoryTaste2T2R46Homo sapiens--chim(Gt3-Gs)/&β;1/&γ;23.082022-10-1210.1126/science.abo1633
7XP6TSensoryTaste2T2R46Homo sapiensStrychnine-chim(Gt3-Gs)/&β;1/&γ;23.012022-10-1210.1126/science.abo1633
7XT8AAmine5-Hydroxytryptamine5-HT4Homo sapiensSerotonin-Gs/&β;1/&γ;23.12022-07-2710.1016/j.molcel.2022.05.031
7XT9AAmine5-Hydroxytryptamine5-HT4Homo sapiensSerotonin-Gs/&β;1/&γ;23.22022-07-2710.1016/j.molcel.2022.05.031
7XTAAAmine5-Hydroxytryptamine5-HT4Homo sapiensSerotonin-Gi1/&β;1/&γ;23.22022-07-2710.1016/j.molcel.2022.05.031
7XTBAAmine5-Hydroxytryptamine5-HT6Homo sapiensSerotonin-Gs/&β;1/&γ;23.32022-07-2710.1016/j.molcel.2022.05.031
7XTCAAmine5-Hydroxytryptamine5-HT7Homo sapiens5-CT-Gs/&β;1/&γ;23.22022-07-2710.1016/j.molcel.2022.05.031
7XTQASteroidBile acidGPBAHomo sapiensR399-Gs/&β;1/&γ;23.22022-07-0610.1073/pnas.2117054119
7XV3AOrphanA orphansGPR174Homo sapiensLysophosphatidylserine-chim(Gi1-Gs)/&β;1/&γ;22.762023-02-1510.1038/s41467-023-36575-0
7XW5AProteinGlycoprotein hormoneTSHHomo sapiensTSHML109Gs/&β;1/&γ;22.962022-08-2410.1038/s41586-022-05173-3
7XW6AProteinGlycoprotein hormoneTSHHomo sapiensM22 FabML109Gs/&β;1/&γ;22.782022-08-1710.1038/s41586-022-05173-3
7XW9APeptideThyrotropin-releasing hormoneTRHHomo sapiensTRH-chim(Gi1-Gs)/&β;1/&γ;22.72022-12-2810.1038/s41421-022-00477-0
7XWOAPeptideTachykininNK2Homo sapiensNeurokinin-A-chim(Gi1-Gs)/&β;1/&γ;22.72023-05-3110.1038/s41421-022-00437-8
7XXHANucleotideP2YP2Y1Homo sapiens2MeSADP-chim(Gi1-G11)/&β;1/&γ;22.92023-06-0710.1093/procel/pwac025
7XXIANucleotideP2YP2Y12Homo sapiens2MeSADP-Gi2/&β;1/&γ;232023-06-0710.1093/procel/pwac025
7XY6ANucleotideAdenosineA2BHomo sapiensPubChem 11717831-chim(Gi1-Gs)/&β;1/&γ;22.992023-05-0310.1126/sciadv.add3709
7XY7ANucleotideAdenosineA2BHomo sapiensNECA-chim(Gi1-Gs)/&β;1/&γ;23.262023-05-0310.1126/sciadv.add3709
7XZ5ALipidGPR119GPR119Homo sapiensLysophosphatidylcholine-Gs/&β;1/&γ;23.12022-08-2410.1038/s41594-022-00816-5
7XZ6ALipidGPR119GPR119Homo sapiensAPD668-Gs/&β;1/&γ;22.82022-08-2410.1038/s41594-022-00816-5
7Y12AOrphanA orphansMRGPRDHomo sapiensBeta-alanine-Gi1/&β;1/&γ;23.12022-07-2010.1038/s42003-022-03668-3
7Y15AOrphanA orphansMRGPRDHomo sapiens--Gi1/&β;1/&γ;22.92022-07-2010.1038/s42003-022-03668-3
7Y1FAPeptideOpioidκHomo sapiensDynorphin-Gi1/&β;1/&γ;23.32023-05-2410.1093/procel/pwac033
7Y24APeptideSomatostatinSST2Homo sapiensOctreotide-Go/&β;1/&γ;23.252022-10-1910.1038/s41589-022-01130-3
7Y26APeptideSomatostatinSST2Homo sapiensOctreotide-chim(Gi2-Gs)/&β;1/&γ;23.32022-10-1910.1038/s41589-022-01130-3
7Y27APeptideSomatostatinSST2Homo sapiensSomatostatin-14-chim(Gi2-Gs)/&β;1/&γ;23.482022-10-1910.1038/s41589-022-01130-3
7Y35B1PeptideParathyroid hormonePTH1Homo sapiensAbaloparatide-Gs/&β;1/&γ;22.92023-07-05To be published
7Y36B1PeptideParathyroid hormonePTH1Homo sapiensTeriparatide-Gs/&β;1/&γ;22.82023-07-05To be published
7Y3GAOrphanA orphansGPR12Homo sapiens--Gs/&β;1/&γ;22.772023-06-0710.1016/j.scib.2022.12.023
7Y64APeptideComplement peptide receptorsC5a1Homo sapiensC5a anaphylatoxin-Gi1/&β;1/&γ;22.92023-03-0110.1038/s41422-023-00779-2
7Y65APeptideComplement peptide receptorsC5a1Homo sapiensC5a peptide-Gi1/&β;1/&γ;23.22023-03-0110.1038/s41422-023-00779-2
7Y66APeptideComplement peptide receptorsC5a1Homo sapiensBM213-Gi1/&β;1/&γ;22.92023-03-0110.1038/s41422-023-00779-2
7Y67APeptideComplement peptide receptorsC5a1Homo sapiensC089 peptide-Gi1/&β;1/&γ;22.82023-03-0110.1038/s41422-023-00779-2
7Y89AOrphanA orphansGPR17 (CysLT)Homo sapiens--Gi1/&β;1/&γ;23.022022-10-1210.1002/mco2.159
7YACAPeptideSomatostatinSST2Homo sapiensPaltusotine-Gi1/&β;1/&γ;23.242023-04-1910.1038/s41467-023-36673-z
7YAEAPeptideSomatostatinSST2Homo sapiensOctreotide-Gi1/&β;1/&γ;23.372023-04-1910.1038/s41467-023-36673-z
7YDHB2AdhesionAdhesionADGRE5Homo sapiens--chim(Gi2-G13)/&β;1/&γ;23.12023-07-1210.1016/j.chembiol.2023.08.003
7YDJB2AdhesionAdhesionADGRE5Homo sapiens--chim(Gi1-G12)/&β;1/&γ;23.032023-07-12To be published
7YDMB2AdhesionAdhesionADGRE5Homo sapiens--chim(Gi1-Gs)/&β;1/&γ;22.892023-07-1210.1016/j.chembiol.2023.08.003
7YDPB2AdhesionAdhesionADGRE5Homo sapiens--chim(Gi1-Gs)/&β;1/&γ;23.12023-07-1210.1016/j.chembiol.2023.08.003
7YFCAAmineHistamineH4Homo sapiensHistamine-chim(Gi1-Gs)/&β;1/&γ;232023-10-2510.1038/s41467-023-42260-z
7YFDAAmineHistamineH4Homo sapiensImetit-chim(Gi1-Gs)/&β;1/&γ;23.12023-10-2510.1038/s41467-023-42260-z
7YJ4APeptideRelaxinRXFP4Homo sapiensINSL5-Gi2/&β;1/&γ;23.192023-03-0110.1038/s41467-023-36182-z
7YK6APeptideRelaxinRXFP4Homo sapiensPubChem 138319674-Gi2/&β;1/&γ;23.032023-03-0110.1038/s41467-023-36182-z
7YK7APeptideRelaxinRXFP4Homo sapiensDC591053-Gi2/&β;1/&γ;22.752023-03-0110.1038/s41467-023-36182-z
7YKDAProteinChemerinCML1Homo sapiensChemerin-9-Gi1/&β;1/&γ;22.812023-04-1910.1073/pnas.2214324120
7YM8AAmineAdrenergicAlpha1AHomo sapiensOxymetazoline-chim(Gi1-Gs)2.922023-07-0510.1038/s41467-023-39310-x
7YMHAAmineAdrenergicAlpha1AHomo sapiensNorepinephrine-chim(Gi1-Gs)3.522023-07-0510.1038/s41467-023-39310-x
7YONAPeptideNeuropeptide YY2Homo sapiensPeptide YY(3-36)-Gi1/&β;1/&γ;22.952023-03-2210.1016/j.str.2022.11.010
7YOOAPeptideNeuropeptide YY2Homo sapiensNeuropeptide Y-Gi1/&β;1/&γ;23.112023-03-2210.1016/j.str.2022.11.010
7YP7B2AdhesionAdhesionADGRG2Mus musculus--Gs/&β;1/&γ;23.12022-08-2410.1038/s41589-022-01084-6
7YS6AAmine5-Hydroxytryptamine5-HT6Homo sapiensSerotonin-chim(Gi-Gs)/&β;1/&γ;232023-03-2910.1073/pnas.2209917120
7YU3ALipidLysophospholipid (LPA)LPA1Homo sapiensONO-0740556-Gi1/&β;1/&γ;23.52022-10-0510.1038/s41467-022-33121-2
7YU5ALipidLysophospholipid (LPA)LPA1Homo sapiensONO-0740556-Gi1/&β;1/&γ;23.72022-10-0510.1038/s41467-022-33121-2
7YU6ALipidLysophospholipid (LPA)LPA1Homo sapiensONO-0740556-Gi1/&β;1/&γ;23.92022-10-0510.1038/s41467-022-33121-2
7YU7ALipidLysophospholipid (LPA)LPA1Homo sapiensONO-0740556-Gi1/&β;1/&γ;24.52022-10-0510.1038/s41467-022-33121-2
7YU8ALipidLysophospholipid (LPA)LPA1Homo sapiensONO-0740556-Gi1/&β;1/&γ;25.62022-10-0510.1038/s41467-022-33121-2
8DCRAAmineAdrenergicβ1Meleagris gallopavoDobutamine-Gs/&β;1/&γ;22.62022-07-2710.1038/s41467-022-31823-1
8DCSAAmineAdrenergicβ1Meleagris gallopavoCyanopindolol-Gs/&β;1/&γ;22.52022-07-2710.1038/s41467-022-31823-1
8DPFAAmine5-Hydroxytryptamine5-HT2CHomo sapiensLorcaserin-chim(Gi1-Gs)/&β;1/&γ;22.842022-08-2410.1016/j.celrep.2022.111211
8DPGAAmine5-Hydroxytryptamine5-HT2CHomo sapiensPsilocin-chim(Gi1-Gs)/&β;1/&γ;23.62022-08-2410.1016/j.celrep.2022.111211
8DPHAAmine5-Hydroxytryptamine5-HT2CHomo sapiensLorcaserin-chim(Gi1-Gs)/&β;1/&γ;23.22022-08-2410.1016/j.celrep.2022.111211
8DPIAAmine5-Hydroxytryptamine5-HT2CHomo sapiensLorcaserin-chim(Gi1-Gs)/&β;1/&γ;23.42022-08-2410.1016/j.celrep.2022.111211
8DWCAOrphanA orphansMRGPRX1Homo sapiensProenkephalin-A-chim(Gi2-Gs)/&β;1/&γ;22.872022-11-0210.1038/s41589-022-01173-6
8DWGAOrphanA orphansMRGPRX1Homo sapiensProenkephalin-AML382chim(Gi2-Gs)/&β;1/&γ;22.712022-11-0210.1038/s41589-022-01173-6
8DWHAOrphanA orphansMRGPRX1Homo sapiensCompound-16-chim(Gi2-Gs)/&β;1/&γ;23.252022-11-0210.1038/s41589-022-01173-6
8DZPAPeptideOpioidκHomo sapiensmomSalB-Gi1/&β;1/&γ;22.712023-05-0310.1038/s41586-023-06030-7
8DZQAPeptideOpioidκHomo sapiensmomSalB-Go/&β;1/&γ;22.822023-05-0310.1038/s41586-023-06030-7
8DZRAPeptideOpioidκHomo sapiensGR89,696-chim(Gi2-Gt3)/&β;1/&γ;22.612023-05-0310.1038/s41586-023-06030-7
8DZSAPeptideOpioidκHomo sapiensGR89,696-chim(Gi2-Gz)/&β;1/&γ;22.652023-05-0310.1038/s41586-023-06030-7
8E3XB1PeptideVIP and PACAPPAC1Homo sapiensPACAP27-Gs/&β;1/&γ;22.32022-11-2310.1038/s41467-022-34629-3
8E3YB1PeptideVIP and PACAPVPAC1Homo sapiensPACAP27-Gs/&β;1/&γ;22.32022-11-2310.1038/s41467-022-34629-3
8E3ZB1PeptideVIP and PACAPVPAC1Homo sapiensVIP-Gs/&β;1/&γ;22.72022-11-2310.1038/s41467-022-34629-3
8E9WAAmineAcetylcholine (muscarinic)M3Homo sapiens2-Deoxycytidine-chim(Gi2-Gs)/&β;1/&γ;22.692022-11-3010.1038/s41586-022-05489-0
8E9XAAmineAcetylcholine (muscarinic)M4Homo sapiens2-Deoxycytidine-Go/&β;1/&γ;22.72022-11-3010.1038/s41586-022-05489-0
8E9YAAmineAcetylcholine (muscarinic)M3Homo sapiensPubChem 446603PubChem 446603chim(Gi2-Gs)/&β;1/&γ;22.792022-11-3010.1038/s41586-022-05489-0
8E9ZAAmineAcetylcholine (muscarinic)M3Homo sapiensIperoxo-chim(Gi2-Gs)/&β;1/&γ;22.692022-11-3010.1038/s41586-022-05489-0
8EF5APeptideOpioidμHomo sapiensFentanyl-Gi1/&β;1/&γ;23.32022-11-0910.1016/j.cell.2022.09.041
8EF6APeptideOpioidμHomo sapiensMorphine-Gi1/&β;1/&γ;23.22022-11-0910.1016/j.cell.2022.09.041
8EFBAPeptideOpioidμHomo sapiensOliceridine-Gi1/&β;1/&γ;23.22022-11-0910.1016/j.cell.2022.09.041
8EFLAPeptideOpioidμHomo sapiensSR17018-Gi1/&β;1/&γ;23.22022-11-0910.1016/j.cell.2022.09.041
8EFOAPeptideOpioidμHomo sapiensPZM21-Gi1/&β;1/&γ;22.82022-11-0910.1016/j.cell.2022.09.041
8EFQAPeptideOpioidμHomo sapiensDamgo-Gi1/&β;1/&γ;23.32022-11-0910.1016/j.cell.2022.09.041
8EITALipidFree fatty acidFFA1 (GPR40)Homo sapiensDoconexent-chim(Gi1-Gs)/&β;1/&γ;22.82023-05-2410.1073/pnas.2219569120
8EJCALipidFree fatty acidFFA1 (GPR40)Homo sapiensTAK-875-chim(Gi1-Gs)/&β;1/&γ;232023-05-2410.1073/pnas.2219569120
8EJKALipidFree fatty acidFFA1 (GPR40)Homo sapiensTAK-875-chim(Gi1-Gs)/&β;1/&γ;23.42023-05-2410.1073/pnas.2219569120
8F0JB1PeptideCalcitoninCTHomo sapiensPramlintide analogue san45-Gs/&β;1/&γ;222023-08-0210.1038/s41589-023-01393-4
8F0KB1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide analogue san385-Gs/&β;1/&γ;2; RAMP31.92023-08-0210.1038/s41589-023-01393-4
8F2AB1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide analogue san385-Gs/&β;1/&γ;2; RAMP32.22023-08-0210.1038/s41589-023-01393-4
8F2BB1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide analogue san45-Gs/&β;1/&γ;2; RAMP322023-08-0210.1038/s41589-023-01393-4
8F76AOlfactory receptorsOlfactoryOR51E2Homo sapiens--Gs/&β;1/&γ;23.12023-03-2210.1038/s41586-023-05798-y
8F7QAPeptideOpioidμHomo sapiensBeta-endorphin-Gi1/&β;1/&γ;23.222022-12-1410.1016/j.cell.2022.12.026
8F7RAPeptideOpioidμHomo sapiensEndomorphin-Gi1/&β;1/&γ;23.282022-12-1410.1016/j.cell.2022.12.026
8F7SAPeptideOpioidδHomo sapiensDeltorphin-Gi1/&β;1/&γ;232022-12-1410.1016/j.cell.2022.12.026
8F7WAPeptideOpioidκHomo sapiensDynorphin-Gi1/&β;1/&γ;23.192022-12-1410.1016/j.cell.2022.12.026
8F7XAPeptideOpioidNOPHomo sapiensNociceptin-Gi1/&β;1/&γ;23.282022-12-1410.1016/j.cell.2022.12.026
8FEGAPeptideOpioidκHomo sapiensPRD_002517-Gi1/β1/γ22.542023-12-06To be published
8FLQB1PeptideParathyroid hormonePTH1Homo sapiensPTH(1-34)-Gs/&β;1/&γ;22.552023-04-2610.1016/j.str.2023.04.002
8FLRB1PeptideParathyroid hormonePTH1Homo sapiensPTHrP(1-36)-Gs/&β;1/&γ;22.942023-04-2610.1016/j.str.2023.04.002
8FLSB1PeptideParathyroid hormonePTH1Homo sapiensAbaloparatide-Gs/&β;1/&γ;23.092023-04-2610.1016/j.str.2023.04.002
8FLTB1PeptideParathyroid hormonePTH1Homo sapiensM-PTH(1-14)-Gs/&β;1/&γ;23.032023-04-2610.1016/j.str.2023.04.002
8FLUB1PeptideParathyroid hormonePTH1Homo sapiensLong-acting PTH-Gs/&β;1/&γ;22.762023-04-2610.1016/j.str.2023.04.002
8FMZAPeptideNeurotensinNTS1Rattus norvegicusNeurotensin/neuromedin N-chim(Gi-Gs)/&β;1/&γ;22.592023-03-2910.1021/acs.biochem.3c00029
8FN0APeptideNeurotensinNTS1Rattus norvegicusNeurotensin/neuromedin NPubChem 118610427Go/&β;1/&γ;22.892023-03-2910.1021/acs.biochem.3c00029
8FN1APeptideNeurotensinNTS1Rattus norvegicusNeurotensin/neuromedin N-Go/&β;1/&γ;22.882023-03-2910.1021/acs.biochem.3c00029
8FU6B1PeptideGlucagonGlucagonHomo sapiensGlucagon derivative ZP3780-Gs/&β;1/&γ;22.92023-04-1210.1016/j.cell.2023.02.028
8FX5AAmineAcetylcholine (muscarinic)M4Homo sapiensXanomelineXanomelineGi1/&β;1/&γ;22.452023-09-1310.1038/s41467-023-41199-5
8G05AOrphanA orphansGPR84Homo sapiens6-OAU-Gi1/&β;1/&γ;232023-11-0110.1038/s41467-023-41201-0
8G2YB2AdhesionAdhesionADGRF1Homo sapiens-LPCGs/&β;1/&γ;23.442023-05-1010.1038/s41467-023-38083-7
8G59ALipidFree fatty acidFFA4 (GPR120)Homo sapiensTUG891-Gi1/&β;1/&γ;22.642023-03-0810.1126/science.add6220
8G94ALipidLysophospholipid (S1P)S1P1Homo sapiens-CD69Gi1/&β;1/&γ;23.152023-04-1910.7554/eLife.88204
8GCMALipidProstanoidEP4Homo sapiensL902688-Gi1/&β;1/&γ;23.52024-01-0310.1073/pnas.2216329120
8GCPALipidProstanoidEP4Homo sapiensPGE2-Gi1/&β;1/&γ;23.12024-01-0310.1073/pnas.2216329120
8GD9ALipidProstanoidEP4Homo sapiensRivenprost-Gs/&β;1/&γ;23.22024-01-0310.1073/pnas.2216329120
8GDAALipidProstanoidEP4Homo sapiensL902688-Gs/&β;1/&γ;23.32024-01-0310.1073/pnas.2216329120
8GDBALipidProstanoidEP4Homo sapiensPGE2-Gs/&β;1/&γ;23.12024-01-0310.1073/pnas.2216329120
8GDCALipidProstanoidEP3Homo sapiensPGE2-Gi1/&β;1/&γ;23.52024-01-0310.1073/pnas.2216329120
8GHVALipidCannabinoidCB1Homo sapiensPubChem 145964903-Gi1/&β;1/&γ;22.82023-05-2410.1038/s41467-023-37864-4
8GUQALipidCannabinoidCB2Homo sapiensOlorinab-Gi1/&β;1/&γ;23.082023-05-1010.1038/s41467-023-37112-9
8GURALipidCannabinoidCB2Homo sapiensPubChem 104895-Gi1/&β;1/&γ;22.842023-05-1010.1038/s41467-023-37112-9
8GUSALipidCannabinoidCB2Homo sapiensHU-308-Gi1/&β;1/&γ;22.972023-05-1010.1038/s41467-023-37112-9
8GUTALipidCannabinoidCB2Homo sapiensLEI-102-Gi1/&β;1/&γ;22.982023-05-1010.1038/s41467-023-37112-9
8GW8B1PeptideParathyroid hormonePTH1Homo sapiens-KHFGs/&β;1/&γ;22.92023-06-1410.1038/s41586-023-06169-3
8GY7APeptideMelanocortinMC2Homo sapiensCorticotropinMRAP1; Cachim(Gi3-Gs)/&β;1/&γ;23.32023-01-1110.1038/s41422-022-00751-6
8H0PAPeptideBombesinBB1Homo sapiensNMB30-chim(Gi1-Gs)/&β;1/&γ;23.152023-08-0910.1038/s41422-022-00743-6
8H0QAPeptideBombesinBB2Homo sapiensGastrin Releasing Peptide-chim(Gi1-Gs)/&β;1/&γ;23.32023-08-0910.1038/s41422-022-00743-6
8H2GAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensNiacin-Gi1/&β;1/&γ;23.012023-10-11To be published
8H4IALipidFree fatty acidFFA4Homo sapiensDoconexent-chim(Gi1-Gs)/&β;1/&γ;23.062023-06-2110.1038/s41422-023-00835-x
8H4KALipidFree fatty acidFFA4Homo sapiensGW9508-chim(Gi1-Gs)/&β;1/&γ;23.12023-06-2110.1038/s41422-023-00835-x
8H4LALipidFree fatty acidFFA4Homo sapiensDoconexent-chim(Gi1-Gs)/&β;1/&γ;23.072023-06-2110.1038/s41422-023-00835-x
8H8JAOrphanA orphansGPR35Homo sapiensLodoxamideCachim(Gi1-G13)/&β;1/&γ;23.22023-02-0810.1038/s41421-022-00499-8
8HA0B1PeptideParathyroid hormonePTH1Homo sapiensPTH-chim(Gi1-Gs)/&β;1/&γ;22.622022-12-2110.1038/s41401-022-01032-z
8HAFB1PeptideParathyroid hormonePTH1Homo sapiensPTHrP(1-36)-chim(Gi1-Gs)/&β;1/&γ;23.252022-12-2110.1038/s41401-022-01032-z
8HAOB1PeptideParathyroid hormonePTH1Homo sapiensPTH-chim(Gi1-Gs)/&β;1/&γ;23.762022-12-2110.1038/s41401-022-01032-z
8HBDAPeptideEndothelinETBHomo sapiensIRL1620-Gi1/&β;1/&γ;22.992023-03-2210.1038/s41467-023-36998-9
8HCQAPeptideEndothelinETAHomo sapiensEndothelin-1-chim(Gi-Gs)/&β;1/&γ;23.012023-03-2210.1038/s41467-023-36998-9
8HCXAPeptideEndothelinETBHomo sapiensEndothelin-1-chim(Gi-Gs)/&β;1/&γ;23.52023-03-2210.1038/s41467-023-36998-9
8HDOANucleotideAdenosineA2BHomo sapiensBAY 60-6583-Gs/&β;1/&γ;22.872023-01-1810.1038/s41421-022-00503-1
8HDPANucleotideAdenosineA2BHomo sapiensAdenosine-Gs/&β;1/&γ;23.22023-01-1810.1038/s41421-022-00503-1
8HIXAOrphanA orphansGPR21Homo sapiens--Gs/&β;1/&γ;23.122023-03-1510.1038/s41467-023-35882-w
8HJ0AOrphanA orphansGPR21Homo sapiens--Gs/&β;1/&γ;23.122023-03-1510.1038/s41467-023-35882-w
8HJ1AOrphanA orphansGPR21Homo sapiens--Gs/&β;1/&γ;23.272023-12-2710.1038/s41467-023-35882-w
8HJ2AOrphanA orphansGPR21Homo sapiens--Gs/&β;1/&γ;23.82023-03-1510.1038/s41467-023-35882-w
8HJ5AOrphanA orphansMRGPRX1Homo sapiensPubChem 139030531-chim(Gi1-Gs)/&β;1/&γ;232023-05-3110.1371/journal.pbio.3001975
8HK2APeptideComplement peptide receptorsC3aBHomo sapiensC3a anaphylatoxin-Gi1/&β;1/&γ;22.92023-05-1010.1038/s41589-023-01339-w
8HK3APeptideComplement peptide receptorsC3aBHomo sapiens--Gi1/&β;1/&γ;23.22023-05-1010.1038/s41589-023-01339-w
8HK5APeptideComplement peptide receptorsC5a1Homo sapiensComplement C5-Gi1/&β;1/&γ;232023-05-1010.1038/s41589-023-01339-w
8HMPAOrphanA orphansGPR52Homo sapiens-PubChem 69921479Gs/&β;1/&γ;22.772023-06-2110.1002/mco2.260
8HMVAOrphanA orphansGPR21Homo sapiens--Gs/&β;1/&γ;22.912023-03-0110.1002/mco2.205
8HN8AAmineHistamineH4Homo sapiensHistamine-Gi1/&β;1/&γ;232023-12-20To be published
8HNKAProteinChemokineCXCR3Homo sapiensCXCL11-Gi1/&β;1/&γ;23.012023-11-2910.1038/s41594-023-01175-5
8HNLAProteinChemokineCXCR3Homo sapiensPS372424-Gi1/&β;1/&γ;22.982023-11-2910.1038/s41594-023-01175-5
8HNMAProteinChemokineCXCR3Homo sapiensVUF11222-Gi1/&β;1/&γ;22.942023-11-2910.1038/s41594-023-01175-5
8HOCAAmineHistamineH4Homo sapiensImetit-Gi1/&β;1/&γ;232023-12-20To be published
8HPTAPeptideComplement peptideC5a1Mus musculusC5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;23.392023-10-1810.1016/j.cell.2023.09.020
8HQCAPeptideComplement peptideC5a1Mus musculusC5a anaphylatoxin-Go/&β;1/&γ;23.892023-10-1810.1016/j.cell.2023.09.020
8HQEAOrphanA orphansGPR132Homo sapiens--Gi1/&β;1/&γ;22.972023-10-110.1038/s42255-023-00899-4
8HQMAOrphanA orphansGPR132Homo sapiensNPGLY-Gi1/&β;1/&γ;22.952023-10-110.1038/s42255-023-00899-4
8HQNAOrphanA orphansGPR132Homo sapiens9(S)-HODE-Gi1/&β;1/&γ;232023-10-110.1038/s42255-023-00899-4
8HS3AOrphanA orphansGPR20Homo sapiens--Gi1/&β;1/&γ;23.142023-03-0810.1038/s41421-023-00520-8
8HSCAOrphanA orphansGPR20Homo sapiensFab046-Gi1/&β;1/&γ;23.222023-03-0810.1038/s41421-023-00520-8
8HTIAOlfactory receptorsOlfactoryOR52CHomo sapiensOcatnoic Acid-Gs/&β;1/&γ;22.972023-12-2010.1038/s41467-023-43983-9
8HVIAOrphanA orphansGPR132Homo sapiensNOX-6-7-Gi1/&β;1/&γ;23.042023-10-110.1038/s42255-023-00899-4
8I2GAProteinGlycoprotein hormoneFSHHomo sapiensGlycoprotein hormones alpha chainCompound 716340Gs/&β;1/&γ;22.82023-03-2910.1038/s41467-023-36170-3
8I95APeptideComplement peptide receptorsC3aBHomo sapiensEP54-Go/&β;1/&γ;22.882023-10-1810.1016/j.cell.2023.09.020
8I97APeptideComplement peptide receptorsC3aBHomo sapiens--Go/&β;1/&γ;23.12023-10-1810.1016/j.cell.2023.09.020
8I9AAPeptideComplement peptide receptorsC3aBHomo sapiensEP54-chim(Gi1-Gs)/&β;1/&γ;23.572023-10-1810.1016/j.cell.2023.09.020
8I9LAPeptideComplement peptide receptorsC3aBHomo sapiensC3a anaphylatoxin-Go/&β;1/&γ;23.182023-10-1810.1016/j.cell.2023.09.020
8I9SAPeptideComplement peptide receptorsC3aBHomo sapiens--Go/&β;1/&γ;23.262023-10-1810.1016/j.cell.2023.09.020
8IA2APeptideComplement peptide receptorsC5a1Homo sapiensC5a anaphylatoxin-Go/&β;1/&γ;23.212023-10-1810.1016/j.cell.2023.09.020
8IA7APeptideCholecystokininCCKBHomo sapiensCholecystokinin-8-chim(Gi1-Gq)/β1/γ23.12023-12-0610.1038/s41421-022-00420-3
8IA8APeptideComplement peptide receptorsC3aBHomo sapiensE7 peptide-Gi1/&β;1/&γ;22.862023-05-24To be published
8IBUAPeptideMotilinMotilinHomo sapiensErythromycin A-chim(Gi1-Gs)/&β;1/&γ;23.512023-04-1210.1126/sciadv.ade9020
8IBVAPeptideMotilinMotilinHomo sapiensMotilin-chim(Gi1-Gs)/&β;1/&γ;23.192023-04-1210.1126/sciadv.ade9020
8IC0AProteinChemokineCXCR1Homo sapiensInterleukin-8-Gi1/&β;1/&γ;23.412023-07-1910.1038/s41467-023-39799-2
8ID3ALipidFree fatty acidFFA4 (GPR120)Homo sapiens9-Hydroxystearic acid-Gi1/&β;1/&γ;23.12023-03-1510.1126/science.add6220
8ID4ALipidFree fatty acidFFA4 (GPR120)Homo sapiensLinoleic acid-Gi1/&β;1/&γ;23.12023-03-1510.1126/science.add6220
8ID6ALipidFree fatty acidFFA4 (GPR120)Homo sapiensOleic acid-Gi1/&β;1/&γ;22.82023-03-1510.1126/science.add6220
8ID8ALipidFree fatty acidFFA4 (GPR120)Homo sapiensTUG891-Gi1/&β;1/&γ;232023-03-1510.1126/science.add6220
8ID9ALipidFree fatty acidFFA4 (GPR120)Homo sapiensEicosapentaenoic acid-Gi1/&β;1/&γ;232023-03-1510.1126/science.add6220
8IHBAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensGSK256073-Gi1/&β;1/&γ;22.852023-09-1310.1038/s41467-023-41650-7
8IHFAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensMK6892-Gi1/&β;1/&γ;22.972023-08-3010.1038/s41467-023-41650-7
8IHHAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensLUF6283-Gi1/&β;1/&γ;23.062023-08-3010.1038/s41467-023-41650-7
8IHIAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensAcifran-Gi1/&β;1/&γ;23.112023-08-3010.1038/s41467-023-41650-7
8IHJAAlicarboxylic acidHydroxycarboxylic acidHCA3Homo sapiensAcifran-Gi1/&β;1/&γ;23.072023-08-3010.1038/s41467-023-41650-7
8IJ3AAlicarboxylic acid receptorsHydroxycarboxylic acid receptorsHCA2Homo sapiens--Gi1/&β;1/&γ;23.282024-01-0310.1038/s41421-023-00610-7
8IJAAAlicarboxylic acid receptorsHydroxycarboxylic acid receptorsHCA2Homo sapiensNiacin-Gi1/&β;1/&γ;22.692024-01-0310.1038/s41421-023-00610-7
8IJBAAlicarboxylic acid receptorsHydroxycarboxylic acid receptorsHCA2Homo sapiensAcipimox-Gi1/&β;1/&γ;23.232024-01-0310.1038/s41421-023-00610-7
8IJDAAlicarboxylic acid receptorsHydroxycarboxylic acid receptorsHCA2Homo sapiensMK-6892-Gi1/&β;1/&γ;23.252024-01-0310.1038/s41421-023-00610-7
8IKLB2AdhesionAdhesionADGRE5Homo sapiens--chim(Gi1-G13)/&β;1/&γ;22.332024-01-2410.1016/j.molcel.2023.12.020
8INRAPeptideMelanocortinMC5Homo sapiensAlpha-MSHCachim(Gi1-Gs)/&β;1/&γ;22.732023-09-2010.1038/s41421-023-00586-4
8IOCAPeptideMelanocortinMC3Homo sapiensGamma-MSHCachim(Gi1-Gs)/&β;1/&γ;22.862023-09-2010.1038/s41421-023-00586-4
8IODAPeptideMelanocortinMC5Homo sapiensPG-901Cachim(Gi1-Gs)/&β;1/&γ;22.592023-09-2010.1038/s41421-023-00586-4
8IRRAAmineDopamineD1Homo sapiensRotigotine-Gs/&β;1/&γ;23.22023-06-0710.1038/s41422-023-00808-0
8IRSAAmineDopamineD2Homo sapiensRotigotine-Gi1/&β;1/&γ;232023-06-0710.1038/s41422-023-00808-0
8IRTAAmineDopamineD3Homo sapiensRotigotine-Gi1/&β;1/&γ;22.72023-06-0710.1038/s41422-023-00808-0
8IRUAAmineDopamineD4Homo sapiensRotigotine-chim(Gi1-Gs)/&β;1/&γ;23.22023-06-0710.1038/s41422-023-00808-0
8IRVAAmineDopamineD5Homo sapiensRotigotine-chim(Gi1-Gs)/&β;1/&γ;23.12023-06-0710.1038/s41422-023-00808-0
8ITFAOrphanA orphansTAAR9Mus musculusDMCHA-chim(Gi1-Gs)/&β;1/&γ;23.462023-05-3110.1038/s41586-023-06106-4
8ITLB1PeptideGlucagonGIPHomo sapiens--Gs/&β;1/&γ;23.232023-10-1810.1073/pnas.2306145120
8ITMB1PeptideGlucagonGIPHomo sapiens--Gs/&β;1/&γ;23.132023-10-1810.1073/pnas.2306145120
8IUKALipidProstanoidFP-alphaHomo sapiensPGF2-alpha-chim(Gi1-Gs)/&β;1/&γ;22.672023-07-1210.1038/s41467-023-38411-x
8IULALipidProstanoidFP-alphaHomo sapiensLatanoprost-chim(Gi1-Gs)/&β;1/&γ;22.782023-07-1210.1038/s41467-023-38411-x
8IUMALipidProstanoidFP-alphaHomo sapiensTafluprost acid-chim(Gi1-Gs)/&β;1/&γ;23.142023-07-1210.1038/s41467-023-38411-x
8IW1AOrphanA orphansTAAR9Mus musculus--chim(Gi1-Gs)/&β;1/&γ;23.42023-05-3110.1038/s41586-023-06106-4
8IW4AOrphanA orphansTAAR9Mus musculusSpermidine-chim(Gi1-Gs)/&β;1/&γ;23.492023-05-3110.1038/s41586-023-06106-4
8IW7AOrphanA orphansTAAR9Mus musculus2-Phenylethylamine-chim(Gi1-Gs)/&β;1/&γ;22.972023-05-3110.1038/s41586-023-06106-4
8IW9AOrphanA orphansTAAR9Mus musculus--chim(Gi1-Gs)/&β;1/&γ;23.082023-05-3110.1038/s41586-023-06106-4
8IY5APeptideEndothelinETBHomo sapiensEndothelin-1-Gi1/&β;1/&γ;22.82023-08-1610.7554/eLife.85821
8IYSALipidFree fatty acidFFA4Homo sapiensTUG891GDPchim(Gi1-Gq)/&β;1/&γ;22.952023-06-2110.1038/s41422-023-00835-x
8IZBAOrphanA orphansGPR174Homo sapiensLysophosphatidylserine-Gs/β1/γ23.062023-11-0110.1371/journal.pbio.3002387
8J18AOrphanA orphansGPR84Homo sapiens(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;22.892023-06-2110.1038/s41467-023-38985-6
8J19AOrphanA orphansGPR84Homo sapiensPubChem 127045422-Gi1/&β;1/&γ;23.232023-06-2110.1038/s41467-023-38985-6
8J1AAOrphanA orphansGPR84Homo sapiens--Gi1/&β;1/&γ;23.242023-06-2110.1038/s41467-023-38985-6
8J20ALipidFree fatty acidFFA3Homo sapiensValeric acidAR420626Gi1/&β;1/&γ;23.22024-01-2410.1038/s41422-023-00914-z
8J21ALipidFree fatty acidFFA3Homo sapiensButyric acid-Gi1/&β;1/&γ;23.32024-01-2410.1038/s41422-023-00914-z
8J22ALipidFree fatty acidFFA2Homo sapiensTUG-1375-Gi1/&β;1/&γ;23.22024-01-2410.1038/s41422-023-00914-z
8J24ALipidFree fatty acidFFA2Homo sapiensAcetic acid-Gi1/&β;1/&γ;22.62024-01-2410.1038/s41422-023-00914-z
8J6DAPeptideComplement peptide receptorsC3aBHomo sapiensEP141-Go/&β;1/&γ;23.12023-10-1810.1016/j.cell.2023.09.020
8J6JAAlicarboxylic acid receptorsHydroxycarboxylic acid receptorsHCA2Homo sapiensGSK256073-Gi1/&β;1/&γ;22.82024-01-1010.1016/j.celrep.2023.113406
8J6PAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensNiacinCompound 9nGi1/β1/γ22.552023-12-0610.1038/s41467-023-43537-z
8J6QAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensBeta-hydroxybutyrateCompound 9nGi1/β1/γ22.62023-12-0610.1038/s41467-023-43537-z
8J6RAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensMK6892-Gi1/β1/γ22.762023-12-0610.1038/s41467-023-43537-z
8J9NFProteinFrizzledFZD1Homo sapiens--Gs/&β;1/&γ;23.52024-01-1710.1038/s41421-023-00627-y
8JD3CAmino acidMetabotropic glutamatemGlu2; mGlu3Homo sapiensGlutamateHZR; PEFGi1/&β;1/&γ;23.32023-06-2110.1038/s41422-023-00830-2
8JD5CAmino acidMetabotropic glutamatemGlu2; mGlu4Homo sapiensGlutamateBQI; HZE; PEFGi1/&β;1/&γ;23.62023-06-2110.1038/s41422-023-00830-2
8JD6CAmino acidMetabotropic glutamatemGlu4; mGlu4Homo sapiensPhosphoserineN-(3-chlorophenyl)pyridine-2-carboxamideGi3/&β;1/&γ;23.42023-06-2110.1038/s41422-023-00830-2
8JGBAOrphanA orphansMRGPRX1Homo sapiensConorfamide-Tx2-Gi1/&β;1/&γ;22.842024-01-10
8JGFAOrphanA orphansMRGPRX1Homo sapiensBAM8-22-chim(Gi1-Gs)/&β;1/&γ;22.72024-01-1010.1038/s41467-023-40705-z
8JGGAOrphanA orphansMRGPRX1Homo sapiensBAM8-22-Gi1/&β;1/&γ;232024-01-1010.1038/s41467-023-40705-z
8JHBFProteinFrizzledFZD6Homo sapiens--chim(GsXLas-Gs)/&β;1/&γ;23.32024-01-1710.1038/s41421-023-00627-y
8JHIFProteinFrizzledFZD3Homo sapiens--chim(GsXLas-Gs)/&β;1/&γ;23.22024-01-1710.1038/s41421-023-00627-y
8JHYAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiens-Compound 9nGi1/&β;1/&γ;22.872023-09-0610.1016/j.molcel.2023.07.030
8JIIAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensNiacinCompound 9nGi1/&β;1/&γ;23.172023-09-0610.1016/j.molcel.2023.07.030
8JILAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensNiacin-Gi1/&β;1/&γ;23.52023-09-0610.1016/j.molcel.2023.07.030
8JIMAAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensMMF-Gi1/&β;1/&γ;22.982023-09-0610.1016/j.molcel.2023.07.030
8JIPB1PeptideGlucagonGLP-1Homo sapiensMEDI0382-chim(Gi1-Gs)/&β;1/&γ;22.852023-09-0610.1073/pnas.2303696120
8JIQB1PeptideGlucagonGlucagonHomo sapiensPeptide 15-Gs/&β;1/&γ;23.42023-09-1310.1073/pnas.2303696120
8JIRB1PeptideGlucagonGLP-1Homo sapiensSAR425899-chim(Gi1-Gs)/&β;1/&γ;22.572023-09-0610.1073/pnas.2303696120
8JISB1PeptideGlucagonGLP-1Homo sapiensPeptide 15-chim(Gi1-Gs)/&β;1/&γ;22.462023-11-0810.1073/pnas.2303696120
8JITB1PeptideGlucagonGlucagonHomo sapiensMEDI0382-Gs/&β;1/&γ;22.912023-09-0610.1073/pnas.2303696120
8JIUB1PeptideGlucagonGlucagonHomo sapiensSAR425899-Gs/&β;1/&γ;22.762023-09-1310.1073/pnas.2303696120
8JLJAAmineTrace amine receptorsTA1Mus musclusT1AM-chim(Gi1-Gs)/&β;1/&γ;23.12023-11-1510.1038/s41586-023-06804-z
8JLKAAmineTrace amine receptorsTA1Mus musclusUlotaront-chim(Gi1-Gs)/&β;1/&γ;23.222023-11-1510.1038/s41586-023-06804-z
8JLNAAmineTrace amine receptorsTA1Homo sapiensT1AM-Gs/&β;1/&γ;23.242023-11-1510.1038/s41586-023-06804-z
8JLOAAmineTrace amine receptorsTA1Homo sapiensUlotaront-Gs/&β;1/&γ;23.522023-11-1510.1038/s41586-023-06804-z
8JLPAAmineTrace amine receptorsTA1Homo sapiensRalmitaront-Gs/&β;1/&γ;23.232023-11-1510.1038/s41586-023-06804-z
8JLQAAmineTrace amine receptorsTA1Homo sapiensFenoldopam-Gs/&β;1/&γ;22.842023-11-1510.1038/s41586-023-06804-z
8JLRAAmineTrace amine receptorsTA1Homo sapiensA77636-chim(Gi1-Gs)/&β;1/&γ;232023-11-1510.1038/s41586-023-06804-z
8JLZAAmine5-Hydroxytryptamine5-HT6Homo sapiensST1936-Gs/&β;1/&γ;23.092023-06-2810.1016/j.bbrc.2023.05.126
8JPBAPeptideNeurotensinNTS1Homo sapiensNeurotensin 8-13PubChem 118610427Gq/&β;1/&γ;2; GRK23.072023-08-0910.1038/s41586-023-06395-9
8JPCAPeptideNeurotensinNTS1Homo sapiensNeurotensin 8-13PubChem 118610427; GDP; MgGq/&β;1/&γ;2; GRK23.072023-08-0910.1038/s41586-023-06395-9
8JR9B1PeptideParathyroid hormonePTH1Homo sapiens-PCO371chim(Gi1-Gs)/&β;1/&γ;22.572023-08-0210.1038/s41586-023-06467-w
8JSOAAmineTrace amine receptorsTA1Homo sapiensAMPH-chim(Gi1-Gs)/&β;1/&γ;23.42023-11-1510.1038/s41586-023-06804-z
8JSPAAmine5-Hydroxytryptamine5-HT1AHomo sapiensUlotaront-Gi1/β1/γ23.652023-11-1510.1038/s41586-023-06804-z
8JZ7AAlicarboxylic acidHydroxycarboxylic acidHCA2Homo sapiensMK6892-Gi1/&β;1/&γ;22.62023-10-0410.1038/s41392-023-01625-y
8JZZAPeptideComplement peptideC5a1Homo sapiensC5a-desArg-Go/&β;1/&γ;23.312023-10-1810.1016/j.cell.2023.09.020
8K2XAProteinChemokineCXCR3Homo sapiensCXCL10-Gi1/&β;1/&γ;23.22023-11-2910.1038/s41594-023-01175-5
8K4NAOrphanA orphansGPR34Homo sapiensVF0-Gi1/&β;1/&γ;22.832023-10-25To be published
8KGKAOrphanA orphansGPR61Homo sapiens--Gs/&β;1/&γ;23.162023-10-1110.1038/s41467-023-41654-3
8KH4AOrphanA orphansGPR161Homo sapiens--Gs/&β;1/&γ;23.12023-10-1110.1038/s41467-023-41654-3
8KH5AOrphanA orphansGPR174Homo sapiensLysophosphatidylserine-Gs/&β;1/&γ;22.832023-10-1110.1038/s41467-023-41654-3
8SAIAOrphanA orphansGPR34Homo sapiens1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;23.272023-10-0410.1073/pnas.2308435120
8SG1AProteinChemerinCML1Homo sapiensChemerin-9-Gi1/&β;1/&γ;22.942023-11-0110.1371/journal.pbio.3002188
8T3OALipidFree fatty acidFFA4Homo sapiensTUG-8912Y5chim(Gi1-Gs)/&β;1/&γ;23.062024-01-1710.1126/sciadv.adj2384
8T3QALipidFree fatty acidFFA4Homo sapiensDHA-chim(Gi1-Gs)/&β;1/&γ;23.142024-01-2410.1126/sciadv.adj2384
8T3SALipidFree fatty acidFFA2Homo sapiensButyric acid-chim(Gi1-Gs)/&β;1/&γ;23.072024-01-2410.1126/sciadv.adj2384
8T3VALipidFree fatty acidFFA1Homo sapiensDHA-chim(Gi1-Gs)/&β;1/&γ;23.392024-01-2410.1126/sciadv.adj2384
8TB0AOrphanA orphansGPR61Homo sapiens--chim(Gi1-Gs)/&β;1/&γ;23.472023-10-0410.1038/s41467-023-41646-3
8THKAAmineAdrenergicAlpha1AHomo sapiensA61603-chim(Gi1-Gs)/&β;1/&γ;22.62023-08-1610.1038/s41467-023-40524-2
8THLAAmineAdrenergicAlpha1AHomo sapiensEpinephrine-chim(Gi1-Gs)/&β;1/&γ;23.12023-08-1610.1038/s41467-023-40524-2
8U1UAProteinChemokineCCR8Homo sapiensCCL1-Gi1/&β;1/&γ;23.12023-12-2010.1038/s41467-023-43601-8
8U26APeptideTachykininNK1Homo sapiensProtachykinin-1-Gs/&β;1/&γ;22.52023-11-1510.1038/s41592-023-02082-9
8UHBAAmineTrace amine receptorsTA1Homo sapiensRO5256390-Gs/&β;1/&γ;23.352024-01-1010.1038/s41467-023-44601-4
8W87AAmineTrace amine receptorsTA1Homo sapiensMETH-chim(Gi1-Gs)/&β;1/&γ;22.82023-11-2210.1038/s41586-023-06775-1
8W88AAmineTrace amine receptorsTA1Homo sapiensSEP-363856-Gs/β1/γ22.62023-11-2210.1038/s41586-023-06775-1
8W89AAmineTrace amine receptorsTA1Homo sapiensPEA-chim(Gi1-Gs)/&β;1/&γ;232023-11-2210.1038/s41586-023-06775-1
8W8AAAmineTrace amine receptorsTA1Homo sapiensRO5256390-chim(Gi1-Gs)/&β;1/&γ;22.82023-11-2210.1038/s41586-023-06775-1
8W8BAAmine5-Hydroxytryptamine5-HT1AHomo sapiensSEP-363856-Gi1/β1/γ232023-11-2210.1038/s41586-023-06775-1
8W8QAOrphanA orphansGPR101Homo sapiens--Gs/&β;1/&γ;22.892024-01-0310.1038/s41589-023-01456-6
8W8RAOrphanA orphansGPR101Homo sapiens-AA-14Gs/&β;1/&γ;23.32024-01-0310.1038/s41589-023-01456-6
8WC3AAmineTrace amine receptorsTA1Mus musculusSEP363856-chim(Gi1-Gs)/&β;1/&γ;232023-12-2710.1016/j.cell.2023.10.014
8WC4AAmineTrace amine receptorsTA1Mus musculusZH8651-chim(Gi1-Gs)/&β;1/&γ;23.12023-12-2710.1016/j.cell.2023.10.014
8WC5AAmineTrace amine receptorsTA1Mus musculusTetramethylammonium ion-chim(Gi1-Gs)/&β;1/&γ;23.32023-12-2710.1016/j.cell.2023.10.014
8WC6AAmineTrace amine receptorsTA1Mus musculus2-Phenylethylamine-chim(Gi1-Gs)/&β;1/&γ;23.22023-12-2710.1016/j.cell.2023.10.014
8WC7AAmineTrace amine receptorsTA1Mus musculusZH8667-chim(Gi1-Gs)/&β;1/&γ;23.12023-12-2710.1016/j.cell.2023.10.014
8WC8AAmineTrace amine receptorsTA1Mus musculusZH8651-chim(Gi1-Gs)/&β;1/&γ;22.92023-12-2710.1016/j.cell.2023.10.014
8WC9AAmineTrace amine receptorsTA1Mus musculusZH8651-chim(Gi1-Gs)/&β;1/&γ;23.22023-12-2710.1016/j.cell.2023.10.014
8WCAAAmineTrace amine receptorsTA1Homo sapiens2-Phenylethylamine-chim(Gi1-Gs)/&β;1/&γ;23.482023-12-2710.1016/j.cell.2023.10.014
8WCBAAmineTrace amine receptorsTA1Mus musculusCyclohexylammonium ion-chim(Gi1-Gs)/&β;1/&γ;23.12023-12-2710.1016/j.cell.2023.10.014
8WPUCIonCalcium-sensingCaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Cachim(Gi1-Gs)/&β;1/&γ;23.12023-11-2210.1038/s41422-023-00892-2
8WRBAOrphanA orphansGPR34Homo sapiensLysophosphatidylserine-Gi1/β1/γ22.912023-11-0810.1371/journal.pbio.3002387
8XBHAOrphanA orphansGPR34Homo sapiensS3E-LysoPS-Gi1/&β;1/&γ;22.832023-12-27To be published