psnGPCRdb

Dimers → Single PSN

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Show: Click this button to access the corresponding database entry page.

PDB: PDB code of the receptor used to compute the network and a direct link to the corresponding entry in the Protein Data Bank.

Class: Receptor Class.

SubFamily: Receptor Sub Family.

Type: Receptor Type.

Subtype: Receptor SubType.

Species: Organism.

Orthosteric Ligand: Name of the orthosteric ligand, if present.

Other Ligand(s): Name of other allosteric ligands, if present.

Protein Partners: G Protein, Arrestin or Kinase coupled to a given receptor.

Resolution: Structure resolution.

Date: Deposition date.

DOI: DOI and link of the corresponding paper.

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ShowPDBClassSubFamilyTypeSubTypeSpeciesOrthosteric LigandOther Ligand(s)Protein PartnersResolutionDateDOI
3CAP (Multimeric) ASensoryOpsinsRhodopsinBos taurus--2.92008-06-24doi.org/10.1038/nature07063
3ODU (Multimeric) AProteinChemokineCXCR4Homo sapiensIT1t-2.52010-10-27doi.org/10.1126/science.1194396
3OE8 (Multimeric) AProteinChemokineCXCR4Homo sapiensIT1t-3.12010-10-27doi.org/10.1126/science.1194396
3OE9 (Multimeric) AProteinChemokineCXCR4Homo sapiensIT1t-3.12010-10-27doi.org/10.1126/science.1194396
4DJH (Multimeric) APeptideOpioidκHomo sapiensJDTic-2.92012-03-21doi.org/10.1038/nature10939
4GPO (Multimeric) AAmineAdrenergicβ1Meleagris gallopavo--3.52013-02-27doi.org/10.1038/nsmb.2504
4JKV (Multimeric) FProteinFrizzledSMOHomo sapiensTaladegib-2.452013-04-24doi.org/10.1038/nature12167
4OR2CAminoacidMetabotropic GlutamatemGlu1; mGlu1Homo sapiens-FITM-2.82014-03-19doi.org/10.1126/science.1249489
5O9H (Multimeric) APeptideComplement PeptideC5a1Homo sapiens-NDT95137272.72018-01-10doi.org/10.1038/nature25025
6AK3 (Multimeric) ALipidProstanoidEP3Homo sapiensPGE2-2.92018-12-05doi.org/10.1038/s41589-018-0171-8
6N51CAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualate--42019-01-23doi.org/10.1038/s41586-019-0881-4
6N52CAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiens---42019-01-23doi.org/10.1038/s41586-019-0881-4
6OFJ (Multimeric) ASensoryOpsinsRhodopsinBos taurus--4.52019-08-21doi.org/10.1074/jbc.RA119.010089
6KUW (Multimeric) AAmineAdrenergicα2cHomo sapiensPubChem 57213234-2.82019-12-04doi.org/10.1038/nature06325
6UO8CAminoacidGABABGABAB1, GABAB2Homo sapiensSKF97541GS39783-3.632020-06-10doi.org/10.1038/s41586-020-2408-4
6UO9CAminoacidGABABGABAB1, GABAB2Homo sapiensSKF97541--4.82020-06-10doi.org/10.1038/s41586-020-2408-4
6UOACAminoacidGABABGABAB1, GABAB2Homo sapiens---6.32020-06-10doi.org/10.1038/s41586-020-2408-4
6VJMCAminoacidGABABGABAB1, GABAB2Homo sapiens---3.972020-06-10doi.org/10.1038/s41586-020-2408-4
6W2YCAminoacidGABABGABAB1; GABAB1Homo sapiensPubChem 5311042--3.22020-07-01doi.org/10.1038/s41586-020-2469-4
6W2XCAminoacidGABABGABAB1, GABAB2Homo sapiensPubChem 5311042--3.62020-07-01doi.org/10.1038/s41586-020-2469-4
6WIVCAminoacidGABABGABAB1, GABAB2Homo sapiens-PubChem 52923113; PubChem 52924645-3.32020-07-01doi.org/10.1038/s41586-020-2452-0
7C7QCAminoacidGABABGABAB1, GABAB2Homo sapiensBaclofenBHFF-32020-07-01doi.org/10.1038/s41422-020-0350-5
7C7SCAminoacidGABABGABAB1, GABAB2Homo sapiensCGP54626--2.92020-07-01doi.org/10.1038/s41422-020-0350-5
6WGT (Multimeric) AAmine5-Hydroxytryptamine5-HT2AHomo sapiensLSD-3.42020-09-23doi.org/10.1016/j.cell.2020.08.024
6WH4 (Multimeric) AAmine5-Hydroxytryptamine5-HT2AHomo sapiensMethiothepin-3.42020-09-23doi.org/10.1016/j.cell.2020.08.024
7CA3CAminoacidGABABGABAB1, GABAB2Homo sapiens-rac-BHFF-4.52020-11-11doi.org/10.1016/j.jmb.2020.09.023
7CA5CAminoacidGABABGABAB1, GABAB2Homo sapiens---7.62020-11-11doi.org/10.1016/j.jmb.2020.09.023
7CUMCAminoacidGABABGABAB1, GABAB2Homo sapiensCGP54626--3.522020-11-11doi.org/10.1016/j.jmb.2020.09.023
7AD3D1Ste2-likeSTE2STE2; STE2Saccharomyces cerevisiaeα-factor mating pheromone-Gi1/STE4/γ23.32020-12-09doi.org/10.1038/s41586-020-2994-1
7DTTCIonCalcium SensingCaS; CaSHomo sapiensCaCa-3.82021-03-10doi.org/10.1038/s41422-021-00474-0
7DTUCIonCalcium SensingCaS; CaSHomo sapiens-Tryptophan-4.42021-03-10doi.org/10.1038/s41422-021-00474-0
7DTVCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Tryptophan-3.52021-03-10doi.org/10.1038/s41422-021-00474-0
7DTWCIonCalcium SensingCaS; CaSHomo sapiens---4.52021-03-10doi.org/10.1038/s41422-021-00474-0
7EB2CAminoacidGABABGABAB2; GABAB1Homo sapiensBaclofenrac-BHFFGi1/β1/γ23.52021-05-05doi.org/10.1038/s41586-021-03507-1
7DD5CIonCalcium SensingCaS; CaSGallus gallusCaCa; Ca; Tryptophan; NPS-2143-3.22021-06-16doi.org/10.1126/sciadv.abg1483
7DD6CIonCalcium SensingCaS; CaSGallus gallusCaCa; Ca; Tryptophan-3.22021-06-16doi.org/10.1126/sciadv.abg1483
7DD7CIonCalcium SensingCaS; CaSGallus gallusCaCa; Ca; Tryptophan; Evocalcet-3.22021-06-16doi.org/10.1126/sciadv.abg1483
7E9GCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensEglumetadJNJ-40411813Gi1/β1/γ23.52021-06-23doi.org/10.1038/s41586-021-03495-2
7EPACAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiens---3.62021-06-23doi.org/10.1038/s41586-021-03641-w
7EPBCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensEglumetad--3.12021-06-23doi.org/10.1038/s41586-021-03641-w
7EPDCAminoacidMetabotropic GlutamatemGlu2, mGlu7Homo sapiens---3.92021-06-23doi.org/10.1038/s41586-021-03641-w
7E9HCAminoacidMetabotropic GlutamatemGlu4; mGlu4Homo sapiensPhosphoserine-Gi3/β1/γ242021-06-23doi.org/10.1038/s41586-021-03495-2
7EPCCAminoacidMetabotropic GlutamatemGlu7; mGlu7Homo sapiens---42021-06-23doi.org/10.1038/s41586-021-03641-w
7M3ECIonCalcium SensingCaS; CaSHomo sapiens-Ca; Ca; Tryptophan; NPS-2143-3.22021-06-30doi.org/10.1038/s41586-021-03691-0
7M3FCIonCalcium SensingCaS; CaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet-2.82021-06-30doi.org/10.1038/s41586-021-03691-0
7M3GCIonCalcium SensingCaS; CaSHomo sapiens-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4-2.52021-06-30doi.org/10.1038/s41586-021-03691-0
7M3JCIonCalcium SensingCaS; CaSHomo sapiens-NPS-2143; PO4-4.12021-06-30doi.org/10.1038/s41586-021-03691-0
7MTQCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensLY341495--3.652021-07-07doi.org/10.1038/s41586-021-03680-3
7MTRCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensGlutamateADX55164-3.32021-07-07doi.org/10.1038/s41586-021-03680-3
7MTSCAminoacidMetabotropic GlutamatemGlu2; mGlu2Homo sapiensGlutamateADX55164Gi1/β1/γ23.22021-07-07doi.org/10.1038/s41586-021-03680-3
7FD8CAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualate--3.82021-09-08doi.org/10.1016/j.celrep.2021.109648
7FD9CAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensLY341495--42021-09-08doi.org/10.1016/j.celrep.2021.109648
7E6TCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; PO4-32021-09-22doi.org/10.7554/eLife.68578
7E6UCIonCalcium SensingCaS; CaSHomo sapiens---62021-09-22doi.org/10.7554/eLife.68578
7DGDCAminoacidMetabotropic GlutamatemGlu1; mGlu1Homo sapiens---3.962021-09-22doi.org/10.1007/s13238-020-00808-5
7DGECAminoacidMetabotropic GlutamatemGlu1; mGlu1Homo sapiensQuisqualate--3.652021-09-22doi.org/10.1007/s13238-020-00808-5
7EWLCOrphanOrphanGPR158; GPR158Homo sapiens---3.522021-12-01doi.org/10.1038/s41467-021-27147-1
7EWPCOrphanOrphanGPR158; GPR158Homo sapiens--B5; RGS74.32021-12-01doi.org/10.1038/s41467-021-27147-1
7EWRCOrphanOrphanGPR158; GPR158Homo sapiens--B5; RGS74.72021-12-01doi.org/10.1038/s41467-021-27147-1
7SHECOrphanOrphanGPR158; GPR158Homo sapiens---3.42021-12-01doi.org/10.1126/science.abl4732
7SHFCOrphanOrphanGPR158; GPR158Homo sapiens--B5; RGS73.42021-12-01doi.org/10.1126/science.abl4732
7SILCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; R-568; PO4-2.72022-01-19doi.org/10.1073/pnas.2115849118
7SIMCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; PO4-2.72022-01-19doi.org/10.1073/pnas.2115849118
7SINCIonCalcium SensingCaS; CaSHomo sapiens-NPS-2143-5.92022-01-19doi.org/10.1073/pnas.2115849118
7WI6CAminoacidMetabotropic GlutamatemGlu3; mGlu3Homo sapiensLY341495--3.712022-03-16doi.org/10.1038/s41422-022-00623-z
7WI8CAminoacidMetabotropic GlutamatemGlu3; mGlu3Homo sapiensLY341495--4.172022-03-16doi.org/10.1038/s41422-022-00623-z
7WIHCAminoacidMetabotropic GlutamatemGlu3; mGlu3Homo sapiensLY2794193--3.682022-03-16doi.org/10.1038/s41422-022-00623-z
7QA8D1Ste2-likeSTE2STE2; STE2Saccharomyces cerevisiaeAntagonist Peptide--2.72022-03-16doi.org/10.1038/s41586-022-04498-3
7QB9D1Ste2-likeSTE2STE2; STE2Saccharomyces cerevisiae---3.12022-03-16doi.org/10.1038/s41586-022-04498-3
7QBCD1Ste2-likeSTE2STE2; STE2Saccharomyces cerevisiaeα-factor mating pheromone--3.532022-03-16doi.org/10.1038/s41586-022-04498-3
7QBID1Ste2-likeSTE2STE2; STE2Saccharomyces cerevisiaeα-factor mating pheromone--3.462022-03-16doi.org/10.1038/s41586-022-04498-3
7W0LAPeptideApelinApelin; ApelinHomo sapiensPubChem 122701908-Gi1/β1/γ23.572022-07-27doi.org/10.1038/s41594-022-00797-5
7W0NAPeptideApelinApelin; ApelinHomo sapiensElabela-Gi1/β1/γ24.212022-07-27doi.org/10.1038/s41594-022-00797-5
8JCUCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--2.82023-06-21doi.org/10.1038/s41422-023-00830-2
8JCVCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--3.42023-06-21doi.org/10.1038/s41422-023-00830-2
8JCWCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--32023-06-21doi.org/10.1038/s41422-023-00830-2
8JCXCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--32023-06-21doi.org/10.1038/s41422-023-00830-2
8JCYCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--2.92023-06-21doi.org/10.1038/s41422-023-00830-2
8JCZCAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensLY341495--32023-06-21doi.org/10.1038/s41422-023-00830-2
8JD0CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamateNAM563-3.32023-06-21doi.org/10.1038/s41422-023-00830-2
8JD1CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamate--3.72023-06-21doi.org/10.1038/s41422-023-00830-2
8JD2CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamate--2.82023-06-21doi.org/10.1038/s41422-023-00830-2
8JD3CAminoacidMetabotropic GlutamatemGlu2; mGlu3Homo sapiensGlutamateJNJ-40411813Gi1/β1/γ23.32023-06-21doi.org/10.1038/s41422-023-00830-2
8JD4CAminoacidMetabotropic GlutamatemGlu2; mGlu4Homo sapiensGlutamate--2.92023-06-21doi.org/10.1038/s41422-023-00830-2
8JD5CAminoacidMetabotropic GlutamatemGlu2; mGlu4Homo sapiensGlutamateJNJ-40411813; ADX88178Gi1/β1/γ23.62023-06-21doi.org/10.1038/s41422-023-00830-2
8JD6CAminoacidMetabotropic GlutamatemGlu4; mGlu4Homo sapiensPhosphoserineVU0364770Gi3/β1/γ23.42023-06-21doi.org/10.1038/s41422-023-00830-2
8FCZ (Multimeric) ASensoryOpsinsRhodopsinBos taurus11-cis-Retinal-3.72023-08-30doi.org/10.1038/s41467-023-40911-9
8FD0 (Multimeric) ASensoryOpsinsRhodopsinBos taurus--3.712023-08-30doi.org/10.1038/s41467-023-40911-9
8FD1 (Multimeric) ASensoryOpsinsRhodopsinBos taurus--4.252023-08-30doi.org/10.1038/s41467-023-40911-9
8T6JCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiens-CDPPB-3.52023-10-11doi.org/10.1101/2023.08.29.555158
8T7HCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualate--3.32023-10-11doi.org/10.1101/2023.08.29.555158
8T8MCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualate--32023-10-11doi.org/10.1101/2023.08.29.555158
8TAOCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualateCDPPB-2.92023-10-11doi.org/10.1101/2023.08.29.555158
8WPGCIonCalcium SensingCaS; CaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Ca-2.72023-11-22doi.org/10.1038/s41422-023-00892-2
8WPUCIonCalcium SensingCaS; CaSHomo sapiens-Tryptophan; Cinacalcet; PO4; Cachim(NtGi2L-Gs-CtGq)/β1/γ23.12023-11-22doi.org/10.1038/s41422-023-00892-2
9ASBCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; R-568; PO4chim(NtGi1-Gs-CtGq)/β1/γ23.42024-04-17doi.org/10.1038/s41586-024-07331-1
9AVGCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; R-568; PO4chim(NtGi1-Gs)/β1/γ23.62024-04-17doi.org/10.1038/s41586-024-07331-1
9AVLCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Cyclomethyltryptophan; R-568; PO4Gi3/β2/γ23.82024-04-17doi.org/10.1038/s41586-024-07331-1
8Z1EAOtherUnclassifiedUL78; UL78; UL78Human herpesvirus 5---3.122024-05-15doi.org/10.1038/s41421-024-00684-x
8YZKCOrphanOrphanGPRC5D; GPRC5DHomo sapiens---3.42024-07-03doi.org/10.1038/s41467-024-49625-y
8TQBCAminoacidMetabotropic GlutamatemGlu3; mGlu3Rattus norvegicusCa; LY379268Ca-3.32024-07-31doi.org/10.1101/2023.08.13.552748
8TR0CAminoacidMetabotropic GlutamatemGlu3; mGlu3Rattus norvegicusLY341495--3.22024-07-31doi.org/10.1101/2023.08.13.552748
8TR2CAminoacidMetabotropic GlutamatemGlu3; mGlu3Rattus norvegicusCa; LY379268Ca-3.52024-07-31doi.org/10.1101/2023.08.13.552748
8TRCCAminoacidMetabotropic GlutamatemGlu3; mGlu3Rattus norvegicusLY341495--3.32024-07-31doi.org/10.1101/2023.08.13.552748
8TRDCAminoacidMetabotropic GlutamatemGlu3; mGlu3Rattus norvegicusLY341495--3.42024-07-31doi.org/10.1038/s41467-024-50548-x
8WM9 (Multimeric) FProteinFrizzledFZD4Homo sapiens--3.532024-09-11doi.org/10.1038/s41467-024-52174-z
9IMACOrphanOrphanGPRC5D; GPRC5DHomo sapiensTalquetamab--2.652024-09-11doi.org/10.1016/j.jmb.2024.168748
8IRJCOrphanOrphanGPR179; GPR179Homo sapiens---3.492024-09-18To be published
9C1PCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Tryptophan; '6218; PO4-2.82024-10-02doi.org/10.1126/science.ado1868
9C2FCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Tryptophan; '54149; PO4-2.82024-10-02doi.org/10.1126/science.ado1868
8X0BCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualateVU0424465-3.12024-11-06doi.org/10.1038/s41467-024-55439-9
8X0CCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualateVU0424465-3.22024-11-06doi.org/10.1038/s41467-024-55439-9
8X0DCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualateVU0424465-3.52024-11-06doi.org/10.1038/s41467-024-55439-9
8X0ECAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualate--3.42024-11-06doi.org/10.1038/s41467-024-55439-9
8X0FCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualateVU29-3.32024-11-06doi.org/10.1038/s41467-024-55439-9
8X0GCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualate--32024-11-06doi.org/10.1038/s41467-024-55439-9
8X0HCAminoacidMetabotropic GlutamatemGlu5; mGlu5Homo sapiensQuisqualate--4.12024-11-06doi.org/10.1038/s41467-024-55439-9
8YU7 (Multimeric) AProteinChemokineCXCR4Homo sapiens--3.012025-03-05doi.org/10.1016/j.celrep.2025.115255
9OPXCSensoryTaste1TAS1R2 ; TAS1R3Homo sapiens; mus musculus---3.632025-09-03To be published
9OPYCSensoryTaste1TAS1R2 ; TAS1R3Homo sapiens; mus musculus---3.512025-09-03To be published
9MDU (Multimeric) AProteinChemokineCXCR4Homo sapiens--2.92025-09-10To be published
9ME1 (Multimeric) AProteinChemokineCXCR4Homo sapiensCXCL12-3.372025-09-10To be published
9MEJ (Multimeric) AProteinChemokineCXCR4Homo sapiensGp120-3.992025-09-10To be published
9MEN (Multimeric) AProteinChemokineCXCR4Homo sapiensGp120 (V3 loop)-3.572025-09-10To be published
9MET (Multimeric) AProteinChemokineCXCR4Homo sapiensGp120; CD4-5.652025-09-10To be published
9MEU (Multimeric) AProteinChemokineCXCR4Homo sapiensCXCL12-3.462025-09-10To be published
9KUWAPeptideApelinApelin; ApelinHomo sapiensCMPD644-Arrestin2 ; Arrestin23.492025-09-17doi.org/10.1038/s41467-025-62870-z
9KUXAPeptideApelinApelin; ApelinHomo sapiensCMPD644-Arrestin23.572025-09-17doi.org/10.1038/s41467-025-62870-z
9M88AOrphanOrphanGPR3 ; GPR3Homo sapiensOleic monoethanolamideAF64394-3.12025-09-24doi.org/10.1038/s41467-025-63422-1
9M8PAOrphanOrphanGPR3 ; GPR3Homo sapiensOleic monoethanolamideAF64394-3.422025-09-24doi.org/10.1038/s41467-025-63422-1
9M8VAOrphanOrphanGPR3 ; GPR3Homo sapiens-AF64394chim(NtGi1-Gs)/β1/γ23.832025-09-24doi.org/10.1038/s41467-025-63422-1
9JQXCAminoacidGABABGABAB1, GABAB2Drosophila melanogasterCGP54626--3.612025-10-01To be published
9MBACAminoacidMetabotropic glutamatemGlu8; mGlu8Homo sapiensGlutamate-Arrestin2 ; Arrestin23.142025-10-01doi.org/10.1016/j.molcel.2025.08.019
9MBBCAminoacidMetabotropic glutamatemGlu8; mGlu8Homo sapiensLY341495--3.252025-10-01doi.org/10.1016/j.molcel.2025.08.019
9MBCCAminoacidMetabotropic glutamatemGlu8; mGlu8Homo sapiensDCPGAZ12216052-2.972025-10-01doi.org/10.1016/j.molcel.2025.08.019
9MBDCAminoacidMetabotropic glutamatemGlu8; mGlu8Homo sapiens---3.322025-10-01doi.org/10.1016/j.molcel.2025.08.019
9KB9AOrphanOrphanLGR4; LGR4Homo sapiensR-spondin-2-ZNRF3; ZNRF33.592025-10-15doi.org/10.1038/s41467-025-64129-z
9JR0CAminoacidGABABGABAB2; GABAB1Drosophila melanogasterGABA-Gi1/β1/γ23.062025-10-22To be published
8SZFCIonCalcium SensingCaS; CaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-2.82024-02-07doi.org/10.1038/s41586-024-07055-2
8SZGCIonCalcium SensingCaS; CaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; Sperminechim(NtGi1-Gq)/β1/γ23.62024-02-07doi.org/10.1038/s41586-024-07055-2
8SZHCIonCalcium SensingCaS; CaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4; SpermineGi1/β1/γ23.12024-02-07doi.org/10.1038/s41586-024-07055-2
8SZICIonCalcium SensingCaS; CaSHomo sapiens-Ca; Ca; Tryptophan; Cinacalcet; PO4Gi3/β1/γ23.52024-02-07doi.org/10.1038/s41586-024-07055-2
8IEBCOrphanOrphanGPR156; GPR156Homo sapiensPubChem 134746894--3.032024-02-14doi.org/10.1038/s41594-024-01224-7
8IEDCOrphanOrphanGPR156; GPR156Homo sapiensPubChem 134746894-Go/β1/γ23.332024-02-14doi.org/10.1038/s41594-024-01224-7
8IEICOrphanOrphanGPR156; GPR156Homo sapiensPubChem 134746894--2.622024-02-14doi.org/10.1038/s41594-024-01224-7
8IEPCOrphanOrphanGPR156; GPR156Homo sapiensPubChem 134746894--2.612024-02-14doi.org/10.1038/s41594-024-01224-7
8U4S (Multimeric) AProteinChemokineCXCR4Homo sapiensREGN7663-Fab-3.352024-03-13doi.org/10.1038/s41594-024-01397-1
8U4T (Multimeric) AProteinChemokineCXCR4Homo sapiensREGN7663-Fab-3.382024-03-13doi.org/10.1038/s41594-024-01397-1
9AXFCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; R-568; PO4chim(NtGi1-Gs-CtGq)/β1/γ23.52024-04-17doi.org/10.1038/s41586-024-07331-1
9AYFCIonCalcium SensingCaS; CaSHomo sapiensCaCa; Ca; Ca; Cyclomethyltryptophan; R-568; PO4Gi1/β1/γ23.62024-04-17doi.org/10.1038/s41586-024-07331-1
8W1V (Multimeric) AAmineAdrenergicβ2Homo sapiensPubChem 171716265-32024-07-17doi.org/10.1021/acs.jmedchem.4c00578
8WGBCAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiensGlutamateVU0155041Gi3/β1/γ23.72024-10-30doi.org/10.1038/s41467-024-54744-7
8WGCCAminoacidMetabotropic GlutamatemGlu2; mGlu4Homo sapiensLY379268--5.952024-11-27doi.org/10.1038/s41467-024-54744-7
8WG9CAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiensPubChem 179394--4.462024-11-27doi.org/10.1038/s41467-024-54744-7
8WGDCAminoacidMetabotropic GlutamatemGlu4; mGlu2Homo sapiensLY341495; CPPG--4.452024-11-27doi.org/10.1038/s41467-024-54744-7
8Y69AOrphanOrphanLGR4; LGR4Homo sapiensR-spondin-2-ZNRF33.382024-12-04doi.org/10.1038/s41467-024-55431-3
8XQEAPeptideApelinApelin; ApelinHomo sapiensApelin-13-Gi1/β1/γ23.482025-01-22doi.org/10.1038/s41467-024-55555-6
8XQIAPeptideApelinApelin; ApelinHomo sapiens---3.252025-01-22doi.org/10.1038/s41467-024-55555-6
8XQJAPeptideApelinApelin; ApelinHomo sapiensJN241--2.952025-01-22doi.org/10.1038/s41467-024-55555-6
8Z74APeptideApelinApelin; ApelinHomo sapiensJN241-9--3.012025-01-22doi.org/10.1038/s41467-024-55555-6
8YJPCOrphanOrphanGPR156; GPR156Homo sapiens---3.092025-02-05doi.org/10.1038/s41467-024-54681-5
8YK0COrphanOrphanGPR156; GPR156Homo sapiens--Gi3/β1/γ22.42025-02-05doi.org/10.1038/s41467-024-54681-5
9II2CAminoacidMetabotropic GlutamatemGlu3; mGlu3Homo sapiensGlutamate-Arrestin2; Arrestin23.72025-03-05doi.org/10.1038/s41589-025-01858-8
9II3CAminoacidMetabotropic GlutamatemGlu3; mGlu3Homo sapiensGlutamate-Arrestin23.92025-03-05doi.org/10.1038/s41589-025-01858-8
9LYCAOrphanOrphanGPR3; GPR3Homo sapiens--Gs/β1/γ23.062025-04-09doi.org/10.1016/j.celrep.2025.115478
9LYDAOrphanOrphanGPR3; GPR3Homo sapiens---3.662025-04-09doi.org/10.1016/j.celrep.2025.115478
9NORCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.42025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOSCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.52025-04-09doi.org/10.1016/j.cell.2025.04.021
9NOTCSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.82025-04-09doi.org/10.1016/j.cell.2025.04.021
9O38CSensoryTaste1TAS1R2; TAS1R3Homo sapiens--chim(Gs-CtGt3)/β1/γ232025-04-09doi.org/10.1016/j.cell.2025.04.021
9OMOCAminoacidMetabotropic GlutamatemGlu7; mGlu7Homo sapiens---4.12025-07-09doi.org/10.1073/pnas.2507112122
9OMPCAminoacidMetabotropic GlutamatemGlu7; mGlu7Homo sapiens---4.32025-07-09doi.org/10.1073/pnas.2507112122
9UT8CSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.412025-07-16doi.org/10.1038/s41586-025-09302-6
9UTACSensoryTaste1TAS1R2; TAS1R3Homo sapiens---3.772025-07-16doi.org/10.1038/s41586-025-09302-6
9UTBCSensoryTaste1TAS1R2; TAS1R3Homo sapiensSucralose--3.592025-07-16doi.org/10.1038/s41586-025-09302-6
9OQ0CSensoryTaste1TAS1R2; TAS1R3Homo sapiens; mus musculus---3.672025-08-27To be published
9LHVB2OrphanOrphanGPR155; GPR155Homo sapiens---2.792025-12-1010.1016/j.scib.2025.09.012
9LHXB2OrphanOrphanGPR155; GPR155Homo sapiens---5.622025-12-1010.1016/j.scib.2025.09.012
8W1ZAOrphanOrphanCeLGR; CeLGRCaenorhabditis elegans---3.792025-12-2410.1038/s41467-025-66676-x
9VORCOrphanOrphanGPR158; GPR158Homo sapiens---3.472025-12-31To be published