psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.11	G.HN.33	6.11	Yes	No	0	2	4
2	G.HN.32	G.HN.33	5.845	No	No	0	5	4
3	G.HN.37	G.HN.41	3.795	No	No	0	3	4
4	G.HN.37	b.b5x2	5.91	No	Yes	0	3	7
5	G.HN.38	G.HN.41	6.075	No	No	0	3	4
6	G.HN.40	b.b5x2	8.195	No	Yes	0	7	7
7	G.HN.40	b.b5x3	4.59	No	Yes	0	7	9
8	G.HN.43	b.b5x3	6.545	No	Yes	0	9	9
9	G.HN.44	b.b5x3	9.68	No	Yes	0	6	9
10	G.HN.47	b.b4x2	3.525	No	Yes	0	6	8
11	G.HN.47	b.b4x4	3.565	No	Yes	0	6	8
12	G.HN.49	G.HN.52	3.805	No	No	0	4	4
13	G.HN.50	b.b4x2	9.68	No	Yes	0	5	8
14	4x38	G.HN.52	9.345	Yes	No	21	7	4
15	4x41	G.HN.52	4.65	No	No	21	6	4
16	G.S1.01	G.S2.05	5.535	No	Yes	2	6	3
17	G.S1.01	G.S3.02	7.385	No	No	2	6	4
18	G.S1.01	G.S3.04	9.45	No	Yes	2	6	6
19	G.S1.02	G.S3.03	13.765	No	Yes	0	5	7
20	G.S1.02	G.h2s4.05	3.175	No	No	0	5	7
21	G.S1.03	G.S3.04	3.59	No	Yes	2	9	6
22	G.S1.03	G.S3.06	6.2	No	Yes	2	9	5
23	G.S1.04	G.S4.03	6.425	No	No	0	7	7
24	G.S1.05	G.S1.07	4.155	Yes	No	0	9	9
25	G.S1.05	G.S3.08	2.98	Yes	Yes	2	9	9
26	G.S1.05	G.h2s4.01	8.53	Yes	Yes	2	9	9
27	G.S1.05	G.S4.02	4.995	Yes	No	0	9	8
28	G.S1.06	G.S3.05	4.945	No	Yes	0	8	7
29	G.S1.06	G.S3.07	3.395	No	Yes	0	8	9
30	G.S1.06	G.S4.03	5.705	No	No	0	8	7
31	G.H3.12	G.S1.07	7.135	No	No	0	8	9
32	G.H1.03	G.s1h1.06	3.64	No	No	0	9	9
33	G.H1.01	G.S3.07	4.15	No	Yes	0	9	9
34	G.H1.04	G.S4.05	4.095	No	No	23	7	7
35	G.H1.04	G.S5.05	5.025	No	Yes	23	7	9
36	G.H1.04	G.S5.07	4.955	No	No	0	7	9
37	G.H1.05	G.S2.04	3.965	No	No	0	6	6
38	G.H1.05	G.S3.07	2.92	No	Yes	0	6	9
39	G.H1.07	G.H5.03	8.58	No	No	0	9	8
40	G.H1.08	G.S2.06	6.22	Yes	No	22	8	9
41	G.H1.08	G.S3.05	5.055	Yes	Yes	22	8	7
42	G.H1.08	G.H5.04	3.8	Yes	No	0	8	7
43	G.H1.08	G.H5.07	3.8	Yes	No	0	8	8
44	G.H1.11	G.S2.08	3.77	No	Yes	0	7	5
45	G.hfs2.07	G.s3h2.03	3.29	No	No	0	9	9
46	G.hfs2.07	b.l7x4	5.09	No	No	0	9	9
47	G.S2.01	G.S3.08	3.84	No	Yes	2	9	9
48	G.S2.01	b.l5x5	4.11	No	Yes	2	9	9
49	G.S2.01	b.l7x2	3.57	No	Yes	2	9	9
50	G.S2.02	G.S3.07	2.92	No	Yes	0	5	9
51	G.S2.03	G.S2.05	4.925	No	Yes	2	9	3
52	G.S2.03	G.S3.04	4.725	No	Yes	2	9	6
53	G.S2.03	G.S3.06	8.16	No	Yes	2	9	5
54	G.S2.04	G.S3.05	3.765	No	Yes	0	6	7
55	G.S2.05	G.S3.02	8.955	Yes	No	2	3	4
56	G.S2.05	G.S3.04	9.825	Yes	Yes	2	3	6
57	G.S2.06	G.S3.03	6.43	No	Yes	0	9	7
58	G.S2.06	G.S3.05	6.845	No	Yes	22	9	7
59	G.S2.07	G.S3.02	6.85	No	No	0	3	4
60	G.S2.08	G.s2s3.01	7.445	Yes	No	15	5	4
61	G.H5.04	G.S2.08	3.275	No	Yes	0	7	5
62	G.H5.08	G.S2.08	17.685	Yes	Yes	15	8	5
63	G.H5.08	G.s2s3.01	6.825	Yes	No	15	8	4
64	G.S3.01	I2x51	7.305	Yes	Yes	0	4	6
65	G.H5.08	G.S3.03	7.5	Yes	Yes	0	8	7
66	G.H5.11	G.S3.03	7.21	No	Yes	0	8	7
67	G.S3.04	G.S3.06	8.065	Yes	Yes	2	6	5
68	G.S3.06	G.h2s4.01	3.75	Yes	Yes	2	5	9
69	G.S3.06	b.l5x5	14.03	Yes	Yes	2	5	9
70	G.H2.07	G.S3.08	6.13	Yes	Yes	2	9	9
71	G.S3.08	G.h2s4.01	5.24	Yes	Yes	2	9	9
72	G.H2.02	G.s3h2.03	4.335	No	No	2	8	9
73	G.H2.07	G.s3h2.03	12.595	Yes	No	2	9	9
74	G.H2.02	G.H2.07	5.56	No	Yes	2	8	9
75	G.H2.02	b.l9x6	5.09	No	Yes	2	8	8
76	G.H2.03	G.H2.05	8.1	Yes	No	0	9	8
77	G.H2.03	G.H2.06	5.4	Yes	Yes	2	9	9
78	G.H2.03	b.l13x6	3.9	Yes	Yes	2	9	9
79	G.H2.03	b.l15x1	6.08	Yes	No	2	9	7
80	G.H2.04	G.H2.07	3.5	Yes	Yes	0	9	9
81	G.H2.04	G.H3.08	5.465	Yes	No	0	9	9
82	G.H2.04	G.H3.11	4.61	Yes	No	0	9	7
83	G.H2.04	G.H3.12	3.76	Yes	No	0	9	8
84	G.H2.06	b.l9x6	3.58	Yes	Yes	2	9	8
85	G.H2.06	b.b14x1	9.36	Yes	No	2	9	8
86	G.H2.06	b.l17x6	9.68	Yes	No	2	9	9
87	G.H2.06	b.b18x1	5.595	Yes	No	2	9	9
88	G.H2.06	b.l19x1	4.15	Yes	Yes	2	9	9
89	G.H2.07	G.H2.08	3.52	Yes	No	0	9	8
90	G.H2.07	G.h2s4.01	4.01	Yes	Yes	2	9	9
91	G.H2.07	b.l7x2	3.42	Yes	Yes	2	9	9
92	G.H2.07	b.l9x6	2.89	Yes	Yes	2	9	8
93	G.H2.08	G.H3.18	5.02	No	Yes	0	8	9
94	G.H2.09	G.H3.17	6.88	No	Yes	9	8	5
95	G.H2.09	b.b2x1	5.985	No	Yes	9	8	8
96	G.H2.09	b.l28x1	6.88	No	Yes	9	8	9
97	G.H2.10	b.b2x1	3.36	No	Yes	9	7	8
98	G.H2.10	b.l3x1	3.05	No	No	9	7	9
99	G.h2s4.01	G.h2s4.04	3.275	Yes	No	0	9	9
100	G.h2s4.01	b.l5x5	9.52	Yes	Yes	2	9	9
101	G.H3.17	G.h2s4.02	11.99	Yes	No	0	5	7
102	G.h2s4.02	b.l1x6	5.4	No	No	0	7	9
103	G.S4.01	G.S5.03	3.25	No	Yes	0	8	8
104	G.H3.18	G.S4.02	10.045	Yes	No	0	9	8
105	G.S4.03	G.S5.03	3.68	No	Yes	0	7	8
106	G.H3.08	G.S4.04	7.31	No	No	0	9	9
107	G.H3.09	G.S4.04	14.465	Yes	No	0	9	9
108	G.H3.12	G.S4.04	4.395	No	No	0	8	9
109	G.S4.05	G.S5.05	4.19	No	Yes	23	7	9
110	G.H3.05	G.S4.06	5.655	No	No	0	9	7
111	G.S4.06	G.S5.06	3.725	No	Yes	0	7	8
112	G.H4.15	G.S4.06	8.525	No	No	0	8	7
113	G.S4.07	G.s5hg.01	3.21	No	No	0	8	9
114	G.S5.06	G.s4h3.01	7.61	Yes	No	0	8	7
115	G.HG.04	G.s4h3.01	8.525	Yes	No	0	9	7
116	G.H4.11	G.s4h3.01	3.565	No	No	0	7	7
117	G.HG.03	G.s4h3.02	3.755	No	No	0	6	9
118	G.s4h3.03	G.s4h3.06	4.07	No	No	11	8	8
119	G.H3.01	G.s4h3.03	17.27	No	No	11	9	8
120	G.s4h3.04	G.s4h3.05	23.565	Yes	No	11	8	9
121	G.HG.04	G.s4h3.04	4.13	Yes	Yes	0	9	8
122	G.HG.07	G.s4h3.04	8.36	No	Yes	11	9	8
123	G.HG.13	G.s4h3.04	3.18	No	Yes	0	7	8
124	G.hgh4.01	G.s4h3.04	6.05	No	Yes	0	6	8
125	G.HG.07	G.s4h3.05	8.99	No	No	11	9	9
126	G.H3.01	G.s4h3.06	5.465	No	No	11	9	8
127	G.H3.03	G.s4h3.15	5.105	No	No	0	4	9
128	G.H3.02	G.hgh4.02	2.995	No	Yes	0	8	7
129	G.H3.02	G.H4.15	3.11	No	No	0	8	8
130	G.H3.03	G.H3.06	3.285	No	Yes	0	4	6
131	G.H3.06	G.hgh4.02	6.585	Yes	Yes	16	6	7
132	G.H3.06	G.H4.14	3.4	Yes	No	16	6	5
133	G.H3.09	G.H3.13	5.585	Yes	Yes	4	9	5
134	G.H3.09	G.S5.02	6.28	Yes	No	4	9	6
135	G.H3.09	G.S5.04	3.65	Yes	Yes	4	9	9
136	G.H3.09	G.S6.01	6.905	Yes	Yes	4	9	5
137	G.H3.10	G.H3.14	8.075	No	No	0	5	8
138	G.H3.10	G.h4s6.01	6.105	No	No	0	5	4
139	G.H3.13	G.S5.02	3.27	Yes	No	4	5	6
140	G.H3.13	G.h4s6.02	3.935	Yes	Yes	4	5	8
141	G.H3.13	G.h4s6.11	4.85	Yes	No	4	5	7
142	G.H3.14	G.h4s6.03	13.985	No	No	0	8	5
143	G.H3.15	G.H3.17	5.085	No	Yes	0	8	5
144	G.H3.15	G.H3.18	3.02	No	Yes	0	8	9
145	G.H3.16	G.H3.17	12.18	No	Yes	0	4	5
146	G.H3.17	b.l25x6	4.5	Yes	Yes	9	5	8
147	G.H3.17	b.l28x1	4.685	Yes	Yes	9	5	9
148	G.H3.18	G.h3s5.03	3.24	Yes	No	0	9	7
149	G.h3s5.01	G.h4s6.04	7.765	No	No	0	3	4
150	G.H5.21	G.h3s5.02	4.15	No	No	0	5	4
151	G.H5.14	G.S5.01	6.46	No	No	0	7	7
152	G.S5.03	G.S5.05	3.77	Yes	Yes	0	8	9
153	G.H5.10	G.S5.03	4.87	No	Yes	0	6	8
154	G.S5.04	G.S5.06	3.46	Yes	Yes	0	9	8
155	G.H4.15	G.S5.04	3.045	No	Yes	0	8	9
156	G.S5.04	G.S6.01	2.855	Yes	Yes	4	9	5
157	G.S5.05	G.S6.04	5.09	Yes	No	0	9	9
158	G.H5.03	G.S5.05	7.855	No	Yes	0	8	9
159	G.S5.06	G.S6.05	8.53	Yes	Yes	0	8	4
160	G.S5.07	G.s6h5.01	5.115	No	No	0	9	9
161	G.H4.03	G.HG.01	5.97	Yes	No	0	4	5
162	G.H4.03	G.HG.05	17.96	Yes	No	0	4	5
163	G.HG.08	G.HG.15	4.995	No	No	0	6	7
164	G.HG.13	G.HG.14	4.45	No	No	0	7	5
165	G.hgh4.01	G.hgh4.02	8.065	No	Yes	0	6	7
166	G.H4.10	G.hgh4.02	4.965	Yes	Yes	16	6	7
167	G.H4.14	G.hgh4.02	5.64	No	Yes	16	5	7
168	G.hgh4.05	G.hgh4.07	6.515	No	No	0	7	7
169	G.H4.05	G.hgh4.05	6.73	No	No	0	4	7
170	G.H4.10	G.hgh4.05	27.8	Yes	No	0	6	7
171	G.H4.02	G.hgh4.08	8.79	No	No	0	5	3
172	G.H4.05	G.hgh4.08	7.905	No	No	0	4	3
173	G.H4.03	G.H4.04	5.05	Yes	No	0	4	4
174	G.H4.03	G.H4.07	4.005	Yes	No	4	4	5
175	G.H4.03	G.S6.05	3.095	Yes	Yes	4	4	4
176	G.H4.07	G.S6.05	3.465	No	Yes	4	5	4
177	G.H4.10	G.H4.14	8.455	Yes	No	16	6	5
178	G.H4.12	G.H4.16	7.005	No	Yes	4	5	3
179	G.H4.12	G.S6.03	17.01	No	No	4	5	5
180	G.H4.12	G.S6.05	6.445	No	Yes	4	5	4
181	G.H4.16	G.S6.01	6.83	Yes	Yes	4	3	5
182	G.H4.16	G.S6.03	6.35	Yes	No	4	3	5
183	G.h4s6.02	G.h4s6.08	9.095	Yes	No	4	8	3
184	G.h4s6.02	G.h4s6.11	4.895	Yes	No	4	8	7
185	G.S6.01	G.h4s6.02	7.08	Yes	Yes	4	5	8
186	G.h4s6.04	G.h4s6.10	3.23	No	No	0	4	3
187	G.h4s6.08	I3	8.4	No	Yes	4	3	4
188	G.S6.02	G.h4s6.12	16.27	No	No	0	7	4
189	G.H5.17	G.h4s6.12	8.1	No	No	0	5	4
190	6x26	G.h4s6.12	8.14	No	No	0	5	4
191	G.H5.10	G.S6.02	4.005	No	No	0	6	7
192	G.H5.13	G.S6.02	4.025	No	No	0	8	7
193	G.H5.06	G.S6.04	16.97	No	No	0	3	9
194	G.s6h5.01	G.s6h5.05	2.89	No	No	0	9	9
195	G.H5.03	G.s6h5.01	4.385	No	No	0	8	9
196	G.H5.02	G.s6h5.05	6.915	No	No	0	4	9
197	G.H5.08	I2x51	3.75	Yes	Yes	15	8	6
198	G.H5.12	G.H5.16	3.04	No	No	0	6	6
199	G.H5.12	I2x51	5.84	No	Yes	0	6	6
200	G.H5.15	I2x54	3.635	No	No	0	7	4
201	G.H5.16	I2x50	5.925	No	No	0	6	9
202	5x68	G.H5.16	2.92	No	No	0	6	6
203	G.H5.17	G.H5.21	5.03	No	No	0	5	5
204	3x53	G.H5.19	3.91	No	No	0	8	8
205	3x54	G.H5.20	5.71	No	No	0	8	9
206	5x65	G.H5.20	3.46	No	No	12	8	9
207	6x30	G.H5.20	4.15	Yes	No	12	8	9
208	G.H5.21	G.H5.26	5.58	No	No	0	5	5
209	2x39	G.H5.23	4.27	No	No	0	8	4
210	3x50	G.H5.23	4.18	Yes	No	0	9	4
211	3x50	G.H5.25	6.07	Yes	No	14	9	7
212	6x37	G.H5.25	8.995	Yes	No	14	8	7
213	6x29	G.H5.26	5.545	No	No	0	6	5
214	6x30	G.H5.26	7.915	Yes	No	0	8	5
215	E2	NT	15.485	Yes	Yes	1	3	3
216	E1	NT	30.405	No	Yes	1	5	3
217	NT	NT	11.045	Yes	Yes	1	3	3
218	7x27	NT	6.365	No	Yes	1	3	3
219	Lig	NT	7.62	Yes	Yes	1	0	3
220	7x28	NT	6.175	No	Yes	0	3	3
221	7x31	NT	11.075	Yes	Yes	1	4	3
222	1x32	NT	6.76	No	Yes	1	5	3
223	7x32	NT	6.24	No	Yes	1	1	3
224	1x30	NT	4.025	No	Yes	1	3	3
225	1x31	7x32	5.72	No	No	1	2	1
226	1x32	2x65	5.09	No	No	0	5	5
227	1x32	2x66	13.34	No	No	0	5	7
228	1x35	1x39	6.31	No	Yes	0	5	7
229	1x35	7x35	9.89	No	No	0	5	4
230	1x36	2x66	10.31	No	No	0	6	7
231	1x39	2x57	5.385	Yes	Yes	1	7	7
232	1x39	7x38	3.49	Yes	Yes	1	7	6
233	1x39	7x39	4.67	Yes	No	0	7	5
234	1x39	7x42	4.965	Yes	Yes	1	7	7
235	1x42	7x43	5.215	No	No	0	7	6
236	1x42	7x47	4.475	No	No	0	7	6
237	1x43	1x47	4.54	Yes	No	0	6	6
238	1x43	2x54	4.87	Yes	No	0	6	6
239	1x43	2x57	8.085	Yes	Yes	0	6	7
240	1x50	2x50	4.04	No	Yes	0	9	9
241	1x50	2x51	4.81	No	No	0	9	8
242	1x50	7x50	9.775	No	No	0	9	9
243	1x52	8x54	5.895	No	Yes	0	6	6
244	1x54	2x48	3.46	No	No	0	7	6
245	1x56	1x59	4.53	Yes	No	0	7	6
246	1x56	8x54	5.835	Yes	Yes	17	7	6
247	2x37	2x40	4.415	No	Yes	6	7	8
248	2x38	3x49	3.525	No	No	0	6	9
249	2x38	4x42	10.205	No	No	0	6	7
250	2x39	3x49	5.705	No	No	0	8	9
251	2x41	4x39	8.23	No	No	0	4	4
252	2x41	4x43	8.36	No	No	0	4	4
253	2x42	3x45	7.24	Yes	No	0	8	7
254	2x42	3x49	8.24	Yes	No	0	8	9
255	2x42	4x42	3.865	Yes	No	0	8	7
256	2x42	4x45	3.81	Yes	No	0	8	5
257	2x42	4x46	3.86	Yes	No	0	8	7
258	2x43	3x46	3.46	No	No	0	8	9
259	2x45	3x42	9.685	No	Yes	0	9	8
260	2x45	4x46	3.87	No	No	0	9	7
261	2x46	2x50	4.07	No	Yes	0	9	9
262	2x46	3x42	5.49	No	Yes	0	9	8
263	2x48	4x50	3.99	No	No	0	6	9
264	2x49	3x39	5.6	No	No	0	8	9
265	2x49	3x42	2.98	No	Yes	0	8	8
266	2x50	3x39	5.06	Yes	No	0	9	9
267	2x50	7x46	4.56	Yes	No	0	9	9
268	2x50	7x49	8.075	Yes	No	0	9	9
269	2x52	3x35	3.175	No	No	0	6	7
270	2x53	3x35	4.965	No	No	0	7	7
271	2x53	7x46	4.01	No	No	0	7	9
272	2x551	3x31	5.535	No	No	0	5	5
273	2x56	3x28	3.335	No	Yes	1	6	6
274	2x56	3x32	3.46	No	Yes	1	6	7
275	2x56	7x42	3.335	No	Yes	1	6	7
276	2x57	2x58	3.35	Yes	No	0	7	9
277	2x57	2x61	3.53	Yes	No	0	7	6
278	2x57	7x42	10.775	Yes	Yes	1	7	7
279	2x59	3x28	6.94	No	Yes	0	5	6
280	2x60	2x64	13.405	Yes	Yes	1	7	6
281	2x60	3x28	5.05	Yes	Yes	1	7	6
282	2x60	7x34	7.855	Yes	Yes	1	7	4
283	2x60	7x38	7.885	Yes	Yes	1	7	6
284	2x60	7x42	8.975	Yes	Yes	1	7	7
285	2x62	2x63	5.81	No	No	0	4	5
286	2x63	E1x52	6.645	No	Yes	1	5	7
287	2x64	3x28	6.705	Yes	Yes	1	6	6
288	2x64	3x29	4.645	Yes	Yes	1	6	5
289	2x64	7x34	8.255	Yes	Yes	1	6	4
290	2x64	Lig	9.42	Yes	Yes	1	6	0
291	E1	E1x49	5.34	No	No	1	5	5
292	E1	Lig	7.745	No	Yes	1	5	0
293	E1x49	E2	4.06	No	Yes	1	5	3
294	E1x50	E1x52	13.03	Yes	Yes	1	9	7
295	3x21	E1x50	3.515	No	Yes	0	8	9
296	E1x50	E2	6.83	Yes	Yes	1	9	3
297	E1x50	E2x50	12.405	Yes	No	1	9	9
298	3x22	E2	6.31	No	Yes	1	3	3
299	3x25	E2x50	7.28	No	No	1	9	9
300	3x26	E2	3.75	No	Yes	1	7	3
301	3x28	3x29	9.93	Yes	Yes	1	6	5
302	3x28	3x32	5.145	Yes	Yes	1	6	7
303	3x29	4x65	9.58	Yes	No	0	5	5
304	3x29	Lig	3.515	Yes	Yes	1	5	0
305	3x30	4x57	3.465	No	No	0	5	7
306	3x30	4x62	9.745	No	No	0	5	5
307	3x32	6x51	9.26	Yes	Yes	1	7	5
308	3x32	7x38	4.22	Yes	Yes	1	7	6
309	3x33	3x37	3.45	Yes	Yes	1	6	6
310	3x33	4x61	10.395	Yes	No	0	6	6
311	3x33	5x43	5.385	Yes	No	1	6	5
312	3x36	6x48	6.065	No	Yes	1	7	8
313	3x37	4x56	12.895	Yes	No	0	6	5
314	3x37	5x43	9.3	Yes	No	1	6	5
315	3x37	5x461	5.72	Yes	No	0	6	6
316	3x38	4x50	5.835	No	No	0	7	9
317	3x38	4x53	3.42	No	No	0	7	8
318	3x39	6x48	4.245	No	Yes	0	9	8
319	3x40	5x50	3.74	No	Yes	0	7	9
320	3x42	4x49	4.25	Yes	No	0	8	8
321	3x44	5x50	3.585	No	Yes	0	7	9
322	3x46	3x50	4.855	No	Yes	14	9	9
323	3x46	7x53	3.515	No	Yes	14	9	9
324	3x47	5x54	3.26	No	No	0	9	8
325	3x47	5x57	6.01	No	No	0	9	7
326	3x47	5x58	4.47	No	No	0	9	9
327	3x48	5x57	2.98	No	No	0	6	7
328	3x50	6x37	3.035	Yes	Yes	14	9	8
329	3x50	7x53	3.085	Yes	Yes	14	9	9
330	3x51	3x55	6.72	Yes	No	0	8	7
331	3x51	3x56	5.445	Yes	No	0	8	6
332	3x51	5x57	12.895	Yes	No	0	8	7
333	3x51	5x60	3.71	Yes	No	0	8	5
334	3x54	5x61	2.945	No	No	0	8	8
335	3x55	5x64	6.465	No	No	0	7	5
336	4x38	4x40	3.26	Yes	No	0	7	4
337	4x38	4x41	9.22	Yes	No	21	7	6
338	4x59	4x60	4.305	No	No	0	4	8
339	4x64	4x65	4.52	Yes	No	0	4	5
340	4x64	E2	4.625	Yes	Yes	1	4	3
341	4x65	E2x52	9.225	No	Yes	0	5	5
342	E2	E2	71.865	Yes	Yes	1	3	3
343	E2	E2x51	14.075	Yes	No	1	3	3
344	E2	Lig	15.025	Yes	Yes	1	3	0
345	E2x51	E2x52	6.12	No	Yes	0	3	5
346	5x36	E2x52	5.115	No	Yes	0	5	5
347	6x58	E2x52	3.61	No	Yes	0	3	5
348	5x35	E2	8.31	No	Yes	0	4	3
349	5x36	E2	3.025	No	Yes	1	5	3
350	5x37	6x60	3.585	No	No	0	4	5
351	5x40	6x55	3.13	No	Yes	1	5	6
352	5x40	6x59	6.545	No	No	0	5	4
353	5x43	6x55	8.435	No	Yes	1	5	6
354	5x44	6x52	9.585	No	Yes	0	5	7
355	5x44	6x56	7.37	No	No	0	5	5
356	5x45	5x46	7.465	No	No	0	4	4
357	5x45	5x48	5.005	No	No	0	4	5
358	5x461	6x52	5.575	No	Yes	0	6	7
359	5x47	5x51	4.975	No	No	0	8	7
360	5x47	6x49	6.7	No	No	0	8	6
361	5x47	6x52	6.225	No	Yes	0	8	7
362	5x49	5x50	4.33	No	Yes	0	5	9
363	5x49	5x53	3.93	No	No	0	5	5
364	5x50	6x44	5.055	Yes	No	0	9	9
365	5x51	6x45	3.04	No	No	0	7	6
366	5x54	6x41	3.155	No	Yes	0	8	8
367	5x58	6x37	9.61	No	Yes	0	9	8
368	5x58	6x41	4.43	No	Yes	0	9	8
369	5x61	6x37	4.28	No	Yes	0	8	8
370	5x65	6x30	5.535	No	Yes	12	8	8
371	5x65	6x34	3.725	No	No	0	8	7
372	5x66	5x70	4.68	No	No	0	5	4
373	5x69	6x27	3.205	Yes	No	12	5	3
374	5x69	6x31	3.27	Yes	No	12	5	6
375	I3	I3	3.44	Yes	Yes	4	4	4
376	6x24	I3	3.41	No	Yes	0	3	4
377	6x26	I3	11.275	No	Yes	4	5	4
378	6x27	6x31	3.925	No	No	12	3	6
379	6x28	6x31	5.84	No	No	0	5	6
380	6x32	7x56	4.035	No	No	0	8	7
381	6x39	7x52	3.155	No	No	0	6	8
382	6x40	7x52	2.98	No	No	0	8	8
383	6x40	7x53	6.31	No	Yes	0	8	9
384	6x44	6x48	8.02	No	Yes	0	9	8
385	6x47	7x45	4.3	No	No	0	8	9
386	6x48	7x41	9.08	Yes	Yes	1	8	7
387	6x48	7x45	8.65	Yes	No	0	8	9
388	6x49	6x50	4.105	No	No	0	6	9
389	6x49	6x53	2.98	No	No	0	6	5
390	6x50	7x40	4.105	No	No	0	9	7
391	6x51	6x52	7.075	Yes	Yes	0	5	7
392	6x51	6x54	5.145	Yes	Yes	1	5	5
393	6x51	6x55	13.89	Yes	Yes	1	5	6
394	6x51	7x41	3.555	Yes	Yes	1	5	7
395	6x54	6x55	5.86	Yes	Yes	1	5	6
396	6x54	7x30	12.35	Yes	Yes	1	5	4
397	6x54	7x33	4.81	Yes	Yes	1	5	5
398	6x54	7x34	11.835	Yes	Yes	1	5	4
399	6x54	7x37	7.115	Yes	No	1	5	5
400	6x54	Lig	3.645	Yes	Yes	1	5	0
401	6x55	Lig	7.285	Yes	Yes	1	6	0
402	6x56	6x59	3.965	No	No	0	5	4
403	6x56	6x60	5.86	No	No	0	5	5
404	6x57	7x33	3.11	No	Yes	0	5	5
405	6x58	7x30	6.19	No	Yes	1	3	4
406	6x58	Lig	12.425	No	Yes	1	3	0
407	6x61	E3	23.2	No	Yes	0	3	3
408	E3	E3	12.5	Yes	Yes	1	3	3
409	E3	Lig	23.125	Yes	Yes	1	3	0
410	7x26	E3	2.85	No	Yes	1	2	3
411	7x30	E3	6.75	Yes	Yes	1	4	3
412	7x23	7x26	10.315	No	No	0	7	2
413	7x27	7x31	17.175	No	Yes	1	3	4
414	7x27	Lig	20.715	No	Yes	1	3	0
415	7x30	7x31	4.355	Yes	Yes	1	4	4
416	7x30	Lig	9.625	Yes	Yes	1	4	0
417	7x31	Lig	3.05	Yes	Yes	1	4	0
418	7x33	7x37	7.78	Yes	No	1	5	5
419	7x34	7x38	6.4	Yes	Yes	1	4	6
420	7x34	Lig	7.2	Yes	Yes	1	4	0
421	7x38	7x42	9.885	Yes	Yes	1	6	7
422	7x41	7x42	3.84	Yes	Yes	1	7	7
423	7x51	7x55	2.855	No	No	0	7	5
424	7x54	8x50	9.665	Yes	Yes	17	7	9
425	7x54	8x54	9.665	Yes	Yes	17	7	6
426	8x47	8x49	3.725	No	No	0	8	7
427	8x48	8x51	4.84	No	No	0	5	9
428	8x50	8x54	8.57	Yes	Yes	17	9	6
429	Lig	Lig	9.27	Yes	Yes	1	0	0
430	b.h2x1	b.h2x5	5.16	No	Yes	0	5	5
431	b.b21x5	b.h2x1	9.19	No	No	0	4	5
432	b.b21x5	b.h2x2	3.07	No	No	0	4	1
433	b.h2x5	b.l24x2	7.37	Yes	Yes	0	5	6
434	b.h2x5	g.h3x9	3.235	Yes	No	0	5	4
435	b.l22x5	b.lhb1x3	3.135	Yes	No	0	9	2
436	b.l24x3	b.lhb1x5	6.69	Yes	No	0	5	1
437	b.l22x5	b.lhb1x6	8.5	Yes	No	24	9	3
438	b.b24x7	b.lhb1x6	5.84	No	No	24	9	3
439	b.lhb1x10	b.lhb1x8	4.675	No	No	0	4	2
440	b.b25x7	b.lhb1x11	6.36	No	Yes	8	7	4
441	b.b28x6	b.lhb1x11	4.07	Yes	Yes	8	9	4
442	b.b1x1	b.b1x3	3.195	No	Yes	0	5	7
443	b.b1x2	b.b28x4	6.005	No	Yes	8	3	6
444	b.b1x2	b.b28x6	8.49	No	Yes	8	3	9
445	b.b1x3	b.b28x7	5.425	Yes	Yes	10	7	9
446	b.b1x3	g.ctx2	3.13	Yes	Yes	10	7	5
447	b.b1x3	g.ctx11	3.49	Yes	No	0	7	8
448	b.b1x4	b.b5x1	3.88	Yes	No	0	7	5
449	b.b1x4	b.b28x5	4.385	Yes	No	0	7	5
450	b.b1x4	g.ctx9	6.415	Yes	Yes	0	7	7
451	b.b1x5	b.l1x1	11.645	No	No	0	3	7
452	b.b1x5	b.b28x4	6.005	No	Yes	0	3	6
453	b.b1x6	b.b3x2	4.15	Yes	Yes	6	9	5
454	b.b1x6	b.b4x6	21.07	Yes	Yes	6	9	9
455	b.b1x6	b.b5x1	3.685	Yes	No	0	9	5
456	b.b1x6	b.b28x3	6.92	Yes	Yes	6	9	7
457	b.b1x6	b.b28x5	6.425	Yes	No	0	9	5
458	b.b28x2	b.l1x1	3.21	No	No	0	4	7
459	b.l1x3	b.l1x7	7.955	Yes	Yes	6	9	9
460	b.b3x4	b.l1x3	5.58	Yes	Yes	6	9	9
461	b.b3x6	b.l1x3	16.04	No	Yes	6	9	9
462	b.l1x3	b.l3x2	3.15	Yes	Yes	6	9	9
463	b.b4x4	b.l1x3	10.605	Yes	Yes	6	8	9
464	b.b4x6	b.l1x3	6.875	Yes	Yes	6	9	9
465	b.l1x4	b.l3x2	4.07	No	Yes	6	6	9
466	b.l1x5	b.l3x2	3.09	No	Yes	0	7	9
467	b.l1x6	b.l28x1	19.15	No	Yes	9	9	9
468	b.b3x4	b.l1x7	3.1	Yes	Yes	6	9	9
469	b.b27x4	b.l1x7	3.53	No	Yes	0	5	9
470	b.b28x3	b.l1x7	4.28	Yes	Yes	6	7	9
471	b.b2x1	b.l3x1	15.22	Yes	No	9	8	9
472	b.b2x1	b.b6x1	5.985	Yes	No	0	8	9
473	b.b2x1	b.l28x1	5.305	Yes	Yes	9	8	9
474	b.b2x3	b.b3x2	4.24	No	Yes	0	6	5
475	b.b26x2	b.b2x3	4.05	No	No	0	7	6
476	b.b10x4	b.b2x4	14.67	No	No	0	6	6
477	b.b2x5	b.b3x2	7.975	Yes	Yes	0	7	5
478	b.b2x5	b.l4x1	5.56	Yes	No	0	7	5
479	b.b2x5	b.l27x1	12.125	Yes	Yes	0	7	7
480	b.b27x2	b.b2x5	5.19	No	Yes	0	5	7
481	b.b6x5	b.l2x1	4.345	Yes	No	0	6	5
482	b.l27x2	b.l2x2	2.89	No	No	0	1	1
483	b.l2x3	b.l2x5	2.975	No	No	0	8	5
484	b.b3x1	b.l2x3	4.07	Yes	No	0	5	8
485	b.l27x1	b.l2x4	5.595	Yes	No	25	7	5
486	b.l27x3	b.l2x4	7.36	No	No	25	7	5
487	b.b4x7	b.l2x5	16.675	No	No	0	8	5
488	b.l2x5	b.l4x2	19.03	No	Yes	0	5	4
489	b.b3x1	b.b4x5	2.855	Yes	Yes	18	5	7
490	b.b3x1	b.b5x4	3.725	Yes	No	0	5	5
491	b.b3x1	b.b6x5	7.03	Yes	Yes	18	5	6
492	b.b3x2	b.b4x6	5.125	Yes	Yes	6	5	9
493	b.b3x3	b.b6x3	3.415	No	No	0	8	8
494	b.b3x3	b.b6x5	7.57	No	Yes	0	8	6
495	b.b3x3	b.b7x2	3.205	No	No	0	8	8
496	b.b3x4	b.b4x6	4.945	Yes	Yes	6	9	9
497	b.b28x3	b.b3x4	6.755	Yes	Yes	6	7	9
498	b.b3x5	b.l5x6	3.395	No	No	0	9	9
499	b.b3x6	b.l3x2	8.095	No	Yes	6	9	9
500	b.b4x2	b.l3x2	5.53	Yes	Yes	0	8	9
501	b.b4x2	b.b5x8	3.345	Yes	No	0	8	5
502	b.b4x3	b.b5x7	8.565	No	Yes	0	7	7
503	b.b4x3	b.l5x1	5.535	No	Yes	19	7	8
504	b.b4x3	b.b7x4	4.76	No	No	19	7	8
505	b.b4x4	b.b4x6	16.44	Yes	Yes	6	8	9
506	b.b4x4	b.b5x3	5.09	Yes	Yes	6	8	9
507	b.b4x5	b.b5x5	7.29	Yes	No	0	7	5
508	b.b4x5	b.b6x5	4.835	Yes	Yes	18	7	6
509	b.b4x5	b.l8x1	3.565	Yes	No	18	7	5
510	b.b4x6	b.b5x3	9.28	Yes	Yes	6	9	9
511	b.b28x3	b.b4x6	3.99	Yes	Yes	6	7	9
512	b.b4x7	b.l4x3	7.225	No	No	0	8	6
513	b.b28x5	b.l4x1	3.87	No	No	0	5	5
514	b.l4x2	g.ctx8	4.87	Yes	No	0	4	9
515	b.b5x2	b.l4x3	10.24	Yes	No	0	7	6
516	b.b5x4	b.b5x5	6.92	No	No	0	5	5
517	b.b5x5	b.l8x8	4.15	No	No	0	5	4
518	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
519	b.b5x7	b.b8x4	9.065	Yes	Yes	0	7	6
520	b.b5x7	b.l8x8	7.68	Yes	No	0	7	4
521	b.l5x1	b.l5x6	2.98	Yes	No	0	8	9
522	b.b7x4	b.l5x1	3.965	No	Yes	19	8	8
523	b.b8x4	b.l5x1	6.445	Yes	Yes	19	6	8
524	b.b9x3	b.l5x2	5.23	Yes	No	0	6	6
525	b.l5x3	b.l7x3	9.57	No	No	0	8	9
526	b.l5x4	b.l5x5	4.325	No	Yes	0	8	9
527	b.l5x5	b.l7x2	7.405	Yes	Yes	2	9	9
528	b.b6x1	b.l9x6	4.19	No	Yes	0	9	8
529	b.b10x2	b.b6x2	3.38	No	No	0	6	8
530	b.b10x3	b.b6x2	5.07	Yes	No	0	8	8
531	b.b6x5	b.l8x1	3.52	Yes	No	18	6	5
532	b.b10x5	b.l6x1	6.24	Yes	No	0	9	6
533	b.l10x3	b.l6x3	7.365	No	No	3	6	6
534	b.b7x1	b.l6x5	6.975	Yes	Yes	3	4	4
535	b.b8x5	b.l6x5	3.405	No	Yes	3	4	4
536	b.l6x5	b.l8x2	10.49	Yes	No	0	4	4
537	b.l10x3	b.l6x5	5.385	No	Yes	3	6	4
538	b.b7x1	b.b8x3	4.835	Yes	Yes	3	4	6
539	b.b7x1	b.b8x5	10.465	Yes	No	3	4	4
540	b.b7x1	b.b9x1	5.085	Yes	No	0	4	4
541	b.b7x1	b.l10x3	6.325	Yes	No	3	4	6
542	b.b7x2	b.l8x1	4.47	No	No	0	8	5
543	b.b10x5	b.b7x3	3.465	Yes	No	0	9	9
544	b.b7x4	b.b8x4	4.035	No	Yes	19	8	6
545	b.l7x2	b.l9x6	2.93	Yes	Yes	2	9	8
546	b.l7x4	b.l9x5	4.24	No	No	0	9	8
547	b.b10x3	b.b8x1	4.55	Yes	No	3	8	8
548	b.b11x4	b.b8x1	3.38	Yes	No	3	9	8
549	b.b8x2	b.b8x4	5.09	No	Yes	0	8	6
550	b.b8x2	b.b9x3	5.745	No	Yes	0	8	6
551	b.b8x3	b.b9x4	3.565	Yes	No	0	6	9
552	b.b10x5	b.b8x3	3.14	Yes	Yes	3	9	6
553	b.b11x2	b.b8x3	2.94	Yes	Yes	3	7	6
554	b.b8x3	b.l12x1	5.89	Yes	No	3	6	6
555	b.b8x4	b.l8x10	5.68	Yes	No	0	6	4
556	b.b8x5	b.l8x3	5.12	No	No	0	4	3
557	b.l8x5	b.l8x7	5.26	No	No	0	3	3
558	b.l8x5	b.l8x9	4.07	No	No	0	3	3
559	b.b9x3	b.l8x10	4.99	Yes	No	0	6	4
560	b.b9x2	b.b9x4	4.25	No	No	0	5	9
561	b.b13x1	b.b9x2	3.75	No	No	0	4	5
562	b.b12x6	b.b9x4	9.68	Yes	No	0	8	9
563	b.l9x3	b.l9x7	5.785	Yes	No	3	9	7
564	b.b11x4	b.l9x3	4.795	Yes	Yes	3	9	9
565	b.b11x6	b.l9x3	13.95	No	Yes	3	9	9
566	b.l11x2	b.l9x3	8.825	Yes	Yes	3	9	9
567	b.b12x4	b.l9x3	2.93	No	Yes	3	4	9
568	b.b12x6	b.l9x3	7.405	Yes	Yes	3	8	9
569	b.l11x2	b.l9x4	5.06	Yes	No	0	9	5
570	b.b10x1	b.l9x6	3.18	No	Yes	0	9	8
571	b.l11x1	b.l9x6	4.345	No	Yes	2	9	8
572	b.l13x6	b.l9x6	10.345	Yes	Yes	2	9	8
573	b.b14x1	b.l9x6	5.39	No	Yes	2	8	8
574	b.b11x4	b.l9x7	4.42	Yes	No	3	9	7
575	b.b10x1	b.b11x5	4.075	No	No	0	9	6
576	b.b10x2	b.b10x4	5.57	No	No	0	6	6
577	b.b10x3	b.b11x2	4.09	Yes	Yes	3	8	7
578	b.b10x3	b.b11x4	4.225	Yes	Yes	3	8	9
579	b.b10x4	b.b14x5	3.645	No	Yes	0	6	5
580	b.b10x5	b.b11x2	6.28	Yes	Yes	3	9	7
581	b.b11x1	b.l10x1	5.99	No	Yes	0	5	3
582	b.b11x3	b.l10x1	3.725	Yes	Yes	7	5	3
583	b.b14x5	b.l10x1	4.15	Yes	Yes	7	5	3
584	b.l10x1	b.l14x4	2.95	Yes	No	0	3	1
585	b.b11x1	b.l10x4	3.3	No	Yes	0	5	3
586	b.l10x4	b.l12x2	11.17	Yes	No	26	3	6
587	b.b11x2	b.l12x1	2.945	Yes	No	3	7	6
588	b.b11x3	b.b14x3	6.705	Yes	No	7	5	5
589	b.b11x3	b.b14x5	2.98	Yes	Yes	7	5	5
590	b.b11x3	b.b15x1	3.935	Yes	Yes	7	5	9
591	b.b11x4	b.b12x6	6.67	Yes	Yes	3	9	8
592	b.b11x5	b.l13x7	6.46	No	No	0	6	9
593	b.b11x5	b.b14x3	4.505	No	No	0	6	5
594	b.b11x6	b.l11x2	6.625	No	Yes	3	9	9
595	b.l11x1	b.l13x6	5.03	No	Yes	2	9	9
596	b.b12x2	b.l11x2	5.78	No	Yes	0	7	9
597	b.b12x2	b.b13x6	3.14	No	No	0	7	4
598	b.b12x3	b.b13x7	4.19	No	Yes	7	8	7
599	b.b12x3	b.b15x3	3.44	No	No	7	8	9
600	b.b12x3	b.b16x6	3.92	No	Yes	7	8	8
601	b.b12x4	b.b12x6	4.54	No	Yes	3	4	8
602	b.b12x4	b.b13x3	3.035	No	Yes	3	4	4
603	b.b12x5	b.b13x4	2.945	No	No	0	6	4
604	b.b12x5	b.b13x7	3.045	No	Yes	0	6	7
605	b.b12x5	b.l16x1	2.98	No	No	0	6	4
606	b.b12x6	b.b13x3	14.24	Yes	Yes	3	8	4
607	b.b12x7	b.l12x2	4.55	No	No	26	9	6
608	b.b12x7	b.l12x3	7.225	No	No	0	9	5
609	b.b13x2	b.l12x3	2.835	No	No	0	4	5
610	b.b13x3	b.b13x6	9.215	Yes	No	0	4	4
611	b.b13x4	b.b13x5	3.925	No	No	0	4	4
612	b.b13x5	b.b13x7	6.49	No	Yes	0	4	7
613	b.b13x7	b.b15x1	5.895	Yes	Yes	7	7	9
614	b.b13x7	b.b16x6	10.525	Yes	Yes	7	7	8
615	b.b13x7	b.b17x1	3.765	Yes	No	0	7	4
616	b.l13x3	b.l13x7	8.3	Yes	No	7	9	9
617	b.b15x3	b.l13x3	5.58	No	Yes	7	9	9
618	b.b15x5	b.l13x3	6.585	No	Yes	7	8	9
619	b.b16x4	b.l13x3	13.755	Yes	Yes	7	6	9
620	b.b16x6	b.l13x3	4.23	Yes	Yes	7	8	9
621	b.l13x4	b.l15x2	10.12	No	No	0	3	9
622	b.l13x5	b.l15x2	5.03	No	No	0	5	9
623	b.l13x6	b.l15x1	3.115	Yes	No	2	9	7
624	b.b15x5	b.l13x7	3.39	No	No	7	8	9
625	b.b14x3	b.b15x1	7.305	No	Yes	7	5	9
626	b.b14x4	b.b18x3	3.095	No	Yes	0	8	8
627	b.b14x4	b.b18x5	5.285	No	Yes	0	8	5
628	b.b14x5	b.b15x1	3.045	Yes	Yes	7	5	9
629	b.b18x5	b.l14x1	6.935	Yes	No	0	5	4
630	b.l14x2	b.l18x4	3.045	No	No	0	4	7
631	b.l14x3	b.l14x5	2.975	No	No	0	5	5
632	b.b15x1	b.b16x6	10.02	Yes	Yes	7	9	8
633	b.b15x2	b.b18x3	4.61	No	Yes	5	6	8
634	b.b15x2	b.b18x5	5.895	No	Yes	0	6	5
635	b.b15x2	b.b19x2	12.455	No	Yes	5	6	6
636	b.b15x3	b.b16x6	6.795	No	Yes	7	9	8
637	b.b15x4	b.l17x7	3.53	No	No	0	6	7
638	b.l15x1	b.l17x6	7	No	No	2	7	9
639	b.b16x2	b.l15x2	3.68	No	No	0	5	9
640	b.b16x4	b.b16x6	5.8	Yes	Yes	7	6	8
641	b.b16x4	b.b17x3	4.04	Yes	No	7	6	5
642	b.b16x4	b.b17x6	15.02	Yes	No	0	6	7
643	b.b16x5	b.b17x7	3.045	Yes	Yes	5	5	8
644	b.b16x5	b.l20x1	8.305	Yes	No	0	5	6
645	b.b16x6	b.b17x3	4.57	Yes	No	7	8	5
646	b.b16x7	b.l16x3	12.99	No	No	27	9	3
647	b.b16x7	b.b17x4	14.89	No	No	27	9	5
648	b.l16x1	b.l16x2	3.27	No	No	0	4	9
649	b.b17x2	b.l16x3	4.74	No	No	0	3	3
650	b.b17x4	b.l16x3	3.49	No	No	27	5	3
651	b.b17x5	b.b17x7	5.855	No	Yes	5	7	8
652	b.b17x5	b.b21x1	14.36	No	Yes	5	7	7
653	b.b17x7	b.b19x2	6.43	Yes	Yes	5	8	6
654	b.b17x7	b.b20x6	9.11	Yes	Yes	5	8	6
655	b.b17x7	b.b21x1	5.375	Yes	Yes	5	8	7
656	b.l17x3	b.l17x7	7.955	Yes	No	5	9	7
657	b.b19x4	b.l17x3	8.9	Yes	Yes	5	8	9
658	b.b19x6	b.l17x3	9.76	No	Yes	5	9	9
659	b.b20x2	b.l17x3	4.11	Yes	Yes	5	6	9
660	b.b20x4	b.l17x3	16.93	Yes	Yes	5	8	9
661	b.b20x6	b.l17x3	3.395	Yes	Yes	5	6	9
662	b.l17x4	b.l19x2	7.795	No	Yes	0	3	9
663	b.l17x5	b.l19x2	7.36	No	Yes	0	6	9
664	b.l17x6	b.l19x1	7.985	No	Yes	2	9	9
665	b.b19x4	b.l17x7	5.32	Yes	No	5	8	7
666	b.b18x1	b.l19x1	10.095	No	Yes	2	9	9
667	b.b18x3	b.b19x2	6.91	Yes	Yes	5	8	6
668	b.b18x3	b.b19x4	4.56	Yes	Yes	5	8	8
669	b.b18x5	b.l18x4	3.765	Yes	No	0	5	7
670	b.b18x5	b.l20x1	3.045	Yes	No	0	5	6
671	b.l18x1	b.l18x2	11.555	Yes	No	13	6	7
672	b.l18x1	b.l18x3	13.29	Yes	Yes	13	6	5
673	b.b19x1	b.l18x1	3.465	No	Yes	0	6	6
674	b.b22x5	b.l18x1	13.93	Yes	Yes	13	7	6
675	b.l18x1	b.l22x4	3.765	Yes	No	13	6	9
676	b.l18x1	g.h3x11	3.095	Yes	No	13	6	3
677	b.b22x5	b.l18x2	2.89	Yes	No	13	7	7
678	b.l18x2	b.l22x4	4.06	No	No	13	7	9
679	b.l18x3	b.l18x5	9.535	Yes	No	0	5	2
680	b.l18x3	g.h3x11	5.235	Yes	No	13	5	3
681	b.l18x5	b.l20x2	6.63	No	Yes	0	2	9
682	b.b19x2	b.b19x4	3.24	Yes	Yes	5	6	8
683	b.b19x2	b.b20x6	10.72	Yes	Yes	5	6	6
684	b.b19x4	b.b20x6	5.19	Yes	Yes	5	8	6
685	b.b19x5	b.l21x9	6.17	No	No	0	5	6
686	b.b19x6	b.l19x2	8.095	No	Yes	5	9	9
687	b.b19x6	b.b20x2	4	No	Yes	5	9	6
688	b.l19x1	b.l21x8	3.355	Yes	No	0	9	4
689	b.b20x2	b.l19x2	5.06	Yes	Yes	5	6	9
690	b.b20x2	b.b20x4	10.995	Yes	Yes	5	6	8
691	b.b20x2	b.l21x1	4	Yes	No	0	6	2
692	b.b20x3	b.b21x7	4.03	No	Yes	0	8	5
693	b.b20x3	b.l21x9	3.275	No	No	0	8	6
694	b.b20x4	b.b20x6	4.81	Yes	Yes	5	8	6
695	b.b20x4	b.b21x3	19.77	Yes	Yes	5	8	6
696	b.b20x4	b.b21x6	5.175	Yes	No	5	8	1
697	b.b20x5	b.b21x4	3.46	No	Yes	0	7	5
698	b.b20x5	b.b21x7	7.62	No	Yes	0	7	5
699	b.b20x6	b.b21x3	5.245	Yes	Yes	5	6	6
700	b.b20x7	b.b21x4	10.18	No	Yes	0	9	5
701	b.b20x7	g.h3x4	5.445	No	No	0	9	5.5
702	b.l20x2	g.h3x7	2.91	Yes	No	0	9	5
703	b.b21x3	b.b21x6	6.35	Yes	No	5	6	1
704	b.b21x5	b.b21x7	9.575	No	Yes	0	4	5
705	b.b21x7	b.b24x6	7.715	Yes	Yes	0	5	8
706	b.l21x2	b.l21x4	5.105	No	No	0	4	4
707	b.b23x6	b.l21x5	5.44	Yes	No	0	7	4
708	b.l21x7	b.l23x1	3.115	No	Yes	0	5	6
709	b.l21x7	b.l23x2	5.445	No	No	0	5	8
710	b.l21x8	b.l23x1	5.87	No	Yes	0	4	6
711	b.b23x6	b.l21x9	9.065	Yes	No	0	7	6
712	b.b22x1	b.l23x1	3.615	No	Yes	9	8	6
713	b.b22x1	b.l25x6	4.53	No	Yes	9	8	8
714	b.b22x4	b.b26x3	3	No	Yes	0	5	6
715	b.b22x4	b.b26x5	3.235	No	No	0	5	7
716	b.b22x5	b.b23x2	9.135	Yes	No	0	7	6
717	b.b23x1	b.l22x1	5.255	No	No	0	5	9
718	b.l22x2	b.l27x4	3.49	No	No	0	1	9
719	b.l22x3	g.l3x4	5.155	No	No	0	9	9
720	b.b24x7	b.l22x5	13.1	No	Yes	24	9	9
721	b.l22x5	b.l24x2	5.465	Yes	Yes	0	9	6
722	b.b23x1	b.b24x5	4.47	No	No	0	5	5
723	b.b23x2	b.b24x6	2.85	No	Yes	0	6	8
724	b.b23x3	b.b24x5	4.47	No	No	0	7	5
725	b.b23x3	b.b26x3	4.84	No	Yes	0	7	6
726	b.b23x3	b.b27x1	4.47	No	No	0	7	6
727	b.b23x4	b.b23x6	5.34	No	Yes	0	6	7
728	b.b23x6	b.b24x4	13.96	Yes	No	20	7	6
729	b.b23x6	b.b24x6	7.235	Yes	Yes	20	7	8
730	b.l23x1	b.l25x6	20.845	Yes	Yes	9	6	8
731	b.b24x2	b.l23x2	5.39	No	No	0	5	8
732	b.b24x2	b.b25x6	4.43	No	No	0	5	3
733	b.b24x3	b.b25x7	3.965	Yes	No	8	5	7
734	b.b24x3	b.l25x7	5.12	Yes	No	0	5	7
735	b.b24x3	b.b26x3	3.17	Yes	Yes	8	5	6
736	b.b24x3	b.b27x3	4.225	Yes	Yes	8	5	8
737	b.b24x4	b.b24x6	3.39	No	Yes	20	6	8
738	b.b24x4	b.b25x3	12.055	No	No	20	6	5
739	b.b24x5	b.b25x5	3.68	No	No	0	5	4
740	b.b24x6	b.b25x3	3.5	Yes	No	20	8	5
741	b.b24x7	b.l24x3	6.22	No	Yes	0	9	5
742	b.b25x7	b.b28x6	24.485	No	Yes	8	7	9
743	b.l25x3	b.l25x7	4.15	Yes	No	0	9	7
744	b.b27x3	b.l25x3	6.845	Yes	Yes	8	8	9
745	b.b27x5	b.l25x3	14.645	No	Yes	8	9	9
746	b.l25x3	b.l28x2	10.08	Yes	Yes	8	9	9
747	b.b28x4	b.l25x3	7.205	Yes	Yes	8	6	9
748	b.l25x4	b.l28x2	3.99	No	Yes	0	5	9
749	b.l25x5	b.l28x1	8.475	No	Yes	0	7	9
750	b.l25x6	b.l28x1	27.99	Yes	Yes	9	8	9
751	b.b26x1	b.b26x2	3.44	No	No	0	9	7
752	b.b26x1	b.l28x1	4.94	No	Yes	0	9	9
753	b.b26x3	b.b27x3	6.635	Yes	Yes	8	6	8
754	b.b26x5	b.b27x1	3.205	No	No	0	7	6
755	b.l27x1	b.l27x3	4.34	Yes	No	25	7	7
756	b.l27x5	g.ctx8	3.355	Yes	No	0	5	9
757	b.b27x3	b.b28x6	7.275	Yes	Yes	8	8	9
758	b.b27x5	b.l28x2	6.625	No	Yes	8	9	9
759	b.b28x2	b.l28x2	10.155	No	Yes	0	4	9
760	b.b28x4	b.b28x6	7.54	Yes	Yes	8	6	9
761	b.b28x7	g.ctx2	5.665	Yes	Yes	10	9	5
762	b.b28x7	g.ctx7	3.405	Yes	Yes	10	9	9
763	g.h3x6	g.h3x9	7.56	No	No	0	4	4
764	g.h3x10	g.h3x6	3.25	No	No	0	1	4
765	g.h3x13	g.h3x9	2.91	No	No	0	6	4
766	g.h3x11	g.h3x15	8.23	No	No	0	3	2
767	g.h3x1	g.l3x4	3.22	No	No	0	5.5	9
768	g.h3x3	g.l3x4	3.65	No	No	0	5	9
769	g.ctx2	g.ctx7	6.37	Yes	Yes	10	5	9
770	g.ctx3	g.ctx5	3.22	Yes	No	0	4	6
771	g.ctx3	g.ctx6	5.225	Yes	No	0	4	5
772	g.ctx7	g.ctx8	4.195	Yes	No	0	9	9
773	g.ctx7	g.ctx9	3.02	Yes	Yes	0	9	7
774	G.HN.30	G.HN.33	3.68	No	No	0	7	4
775	G.H1.07	G.s6h5.04	2.835	No	No	0	9	8
776	G.s2s3.01	I2x51	3.72	No	Yes	15	4	6
777	G.S3.01	I2x54	3.525	Yes	No	0	4	4
778	G.H3.06	G.h4s6.01	2.825	Yes	No	0	6	4
779	G.HG.04	G.HG.08	5.025	Yes	No	0	9	6
780	G.h4s6.09	G.h4s6.10	2.89	No	No	0	3	3
781	G.H5.13	G.H5.17	4.84	No	No	0	8	5
782	2x35	G.H5.19	3.435	No	No	0	8	8
783	2x36	G.H5.22	7.83	Yes	No	0	7	4
784	b.1x4	g.h1x8	2.98	No	Yes	0	8	0
785	b.1x7	g.h1x8	2.85	No	Yes	0	8	0
786	b.1x19	b.b21x1	2.98	No	Yes	0	6	7
787	b.lh12x2	g.h2x2	4.415	No	No	0	8	0
788	b.h2x3	b.lh12x4	4.25	No	No	0	1	3
789	b.b21x4	b.h2x1	6.23	Yes	No	0	5	5
790	b.b1x4	g.ctx16	4.275	Yes	Yes	0	7	8
791	I1	b.l1x4	4.66	Yes	No	6	5	6
792	b.b2x1	b.l1x6	2.985	Yes	No	9	8	9
793	b.l4x2	g.ctx15	5.565	Yes	Yes	10	4	9
794	b.l4x2	g.ctx16	3.61	Yes	Yes	10	4	8
795	b.l6x3	b.l6x5	2.98	No	Yes	3	6	4
796	b.b9x3	b.l7x5	3.415	Yes	No	0	6	6
797	b.b12x7	b.l10x4	6.73	No	Yes	26	9	3
798	b.b16x5	b.b17x5	3.995	Yes	No	5	5	7
799	b.b17x6	g.h1x14	4.235	No	No	0	7	0
800	b.l18x1	g.h2x8	3.045	Yes	No	0	6	0
801	b.l18x3	g.h2x11	2.905	Yes	No	0	5	6
802	b.l20x2	g.h2x7	2.98	Yes	No	0	9	0
803	b.b21x1	g.l1x4	6.55	Yes	Yes	0	7	0
804	b.b21x2	g.h2x1	2.865	No	No	0	6	0
805	b.l22x1	g.ctx3	4.415	No	Yes	0	9	4
806	b.l22x2	g.ctx2	4.05	No	Yes	0	1	5
807	b.l22x3	g.ctx3	5.155	No	Yes	0	9	4
808	b.l27x5	g.ctx4	3.355	Yes	No	0	5	6
809	b.l27x5	g.ctx15	3.355	Yes	Yes	0	5	9
810	b.b28x7	g.ctx14	4.77	Yes	No	10	9	7
811	b.b28x7	g.ctx16	3.02	Yes	Yes	10	9	8
812	g.h1x10	g.h1x14	5.735	No	No	0	0	0
813	g.h2x3	g.h2x7	4.15	No	No	0	0	0
814	g.h2x11	g.h2x15	7.62	No	No	0	6	6
815	g.ctx2	g.h2x15	3.075	Yes	No	0	5	6
816	g.ctx14	g.ctx15	3.26	No	Yes	10	7	9
817	g.ctx14	g.ctx16	3.02	No	Yes	10	7	8
818	g.ctx15	g.ctx16	5.78	Yes	Yes	10	9	8
819	1x28	1x31	2.945	No	No	1	0	2
820	1x28	7x32	5.17	No	No	1	0	1
821	1x53	7x54	4.385	No	Yes	0	9	7
822	1x55	1x59	6.95	No	No	0	3	6
823	1x56	8x50	3.89	Yes	Yes	17	7	9
824	1x60	I1	3	No	Yes	0	0	5
825	I1	I1	6.345	Yes	Yes	6	5	5
826	2x37	I1	4.52	No	Yes	6	7	5
827	2x40	I1	7.715	Yes	Yes	6	8	5
828	4x39	I1	5.84	No	Yes	6	4	5
829	2x34	2x36	4.33	No	Yes	0	0	7
830	2x35	I2x57	2.825	No	No	0	8	6
831	2x36	2x40	3.71	Yes	Yes	0	7	8
832	2x37	4x39	4.61	No	No	6	7	4
833	2x45	4x50	3.09	No	No	0	9	9
834	2x46	7x53	3.515	No	Yes	0	9	9
835	2x51	2x55	3.46	No	No	0	8	5
836	2x60	3x32	4.65	Yes	Yes	1	7	7
837	2x62	2x67	4.415	No	No	0	4	5
838	2x63	E1x50	4.52	No	Yes	1	5	9
839	3x25	E1x50	4.57	No	Yes	1	9	9
840	3x22	3x26	7.145	No	No	1	3	7
841	3x36	7x41	3.89	No	Yes	1	7	7
842	5x40	Lig	2.855	No	Yes	1	5	0
843	6x51	7x38	2.905	Yes	Yes	1	5	6
844	7x49	7x53	3.49	No	Yes	0	9	9
845	7x55	8x54	3.655	No	Yes	0	5	6
846	2x35	I2x54	2.82	No	No	0	8	4
847	b.b26x4	b.b2x5	2.81	No	Yes	0	5	7
848	b.b28x6	b.l25x2	2.81	Yes	No	0	9	5
849	1x46	7x47	2.795	No	No	0	8	6
850	b.b4x1	b.l5x4	2.785	No	No	0	8	8
851	b.l27x6	g.ctx16	2.775	No	Yes	0	7	8
852	2x52	2x551	2.77	No	No	0	6	5
853	b.b16x3	b.b19x2	2.77	No	Yes	0	6	6
854	b.b19x3	b.b22x5	2.77	No	Yes	0	4	7
855	b.b16x5	b.l14x6	2.765	Yes	No	0	5	3
856	b.lh12x2	g.l1x6	2.765	No	No	0	8	0
857	6x33	6x36	2.76	No	No	0	8	8
858	b.b23x5	b.l25x7	2.76	No	No	0	7	7
859	b.h2x3	b.h2x4	2.745	No	Yes	0	1	3
860	G.H4.01	G.HG.15	2.745	No	No	0	3	7
861	2x43	7x54	2.745	No	Yes	0	8	7
862	b.l13x1	b.l13x2	2.73	No	No	0	2	6
863	b.l17x1	b.l17x2	2.73	No	No	0	2	6
864	b.lhb1x1	b.lhb1x2	2.725	No	No	0	1	1
865	g.h1x10	g.h1x13	2.72	No	No	0	0	0
866	G.s4h3.05	G.s4h3.06	2.715	No	No	11	9	8
867	G.HG.02	G.HG.03	2.715	No	No	0	9	6
868	b.1x1	b.1x2	2.715	No	No	0	4	1
869	G.H5.02	G.H5.05	2.71	No	No	0	4	5
870	G.H3.04	G.s4h3.14	2.705	No	No	0	9	6
871	G.s1h1.04	G.s5hg.01	2.7	No	No	0	9	9
872	b.b21x7	b.b25x1	2.67	Yes	No	0	5	2
873	G.HG.03	G.HG.06	2.655	No	No	0	6	5
874	b.l21x2	b.l21x5	2.65	No	No	0	4	4
875	g.ctx10	g.ctx9	2.65	No	Yes	0	8	7
876	8x47	8x50	2.64	No	Yes	0	8	9
877	3x56	I2x52	2.62	No	No	0	6	5
878	b.b6x1	b.l7x1	2.62	No	No	0	9	9
879	b.b5x3	b.l1x2	2.615	Yes	No	0	9	9
880	b.b10x2	b.b14x2	2.58	No	No	0	6	7
881	1x57	2x40	2.57	No	Yes	0	7	8
882	G.HN.51	b.l1x4	2.565	No	No	0	5	6
883	G.H3.05	G.s1h1.02	2.565	No	No	0	9	7
884	G.S4.07	G.s1h1.05	2.565	No	No	0	8	9
885	6x47	7x43	2.565	No	No	0	8	6
886	b.b7x5	b.l9x7	2.565	No	No	0	9	7
887	b.b14x2	b.b18x2	2.565	No	No	0	7	5
888	b.l18x3	b.l18x4	2.545	Yes	No	0	5	7
889	b.b18x2	b.b22x3	2.545	No	No	0	5	6
890	3x43	7x53	2.525	No	Yes	0	8	9
891	1x53	2x47	2.52	No	No	0	9	9
892	b.l27x5	g.h3x1	2.515	Yes	No	0	5	5.5
893	b.l20x2	g.l1x5	2.505	Yes	No	0	9	0
894	G.HN.39	G.HN.42	2.48	No	No	0	5	4
895	G.HN.43	b.b5x6	2.435	No	No	0	9	6
896	b.b25x4	b.lhb1x9	2.435	No	No	0	4	3
897	b.h2x4	g.h2x5	2.435	Yes	No	0	3	0
898	b.b17x4	b.l14x6	2.43	No	No	0	5	3
899	b.1x4	g.h1x5	2.43	No	No	0	8	0
900	G.HG.01	G.s6h5.02	2.425	No	No	0	5	7
901	5x55	6x41	2.425	No	Yes	0	5	8
902	b.b24x1	b.l25x5	2.415	No	No	0	4	7
903	b.1x13	b.1x16	2.41	No	No	0	1	4
904	6x36	7x56	2.405	No	No	0	8	7
905	b.b16x2	b.b17x6	2.4	No	No	0	5	7
906	3x37	5x46	2.395	Yes	No	0	6	4
907	G.H5.14	G.h2s4.05	2.38	No	No	0	7	7
908	b.b21x4	g.h3x5	2.38	Yes	No	0	5	6
909	b.l24x2	g.h2x12	2.38	Yes	No	0	6	7
910	G.hfs2.06	b.l9x4	2.355	No	No	0	7	5
911	b.b12x2	b.l13x1	2.355	No	No	0	7	2
912	G.HG.02	G.s6h5.02	2.335	No	No	0	9	7
913	b.1x19	b.b21x2	2.335	No	No	0	6	6
914	g.h3x14	g.h3x15	2.325	No	No	0	3	2
915	G.S4.07	G.s4h3.03	2.315	No	No	0	8	8
916	3x33	4x57	2.315	Yes	No	0	6	7
917	b.l14x1	b.l14x3	2.315	No	No	0	4	5
918	7x43	7x48	2.305	No	No	0	6	6
919	b.b21x2	b.lh12x1	2.275	No	No	0	6	3
920	5x41	6x60	2.255	No	No	0	6	5
921	G.HN.10	G.HN.34	2.25	No	No	0	4	3
922	b.b22x2	b.b26x3	2.25	No	Yes	0	8	6
923	3x41	4x53	2.25	No	No	0	7	8
924	5x69	6x30	2.235	Yes	Yes	12	5	8
925	b.l24x2	g.h3x12	2.235	Yes	No	0	6	6
926	1x51	2x51	2.225	No	No	0	4	8
927	G.S3.01	I2x55	2.21	Yes	No	0	4	4
928	1x38	1x42	2.205	No	No	0	4	7
929	b.lhb1x11	b.lhb1x9	2.19	Yes	No	0	4	3
930	b.b6x5	b.l6x4	2.175	Yes	No	0	6	5
931	b.l27x1	b.l27x2	2.17	Yes	No	0	7	1
932	G.H5.01	G.s6h5.05	2.17	No	No	0	9	9
933	b.lhb1x11	g.h3x2	2.12	Yes	No	0	4	8
934	G.s3h2.01	G.s3h2.02	2.11	No	No	0	9	9
935	G.h4s6.09	I3	2.1	No	Yes	4	3	4
936	b.l7x3	b.l7x5	2.1	No	No	0	9	6
937	b.b28x1	b.l1x3	2.09	No	Yes	0	4	9
938	G.H4.06	G.HG.04	2.08	No	Yes	0	7	9
939	E1x51	E1x52	2.08	No	Yes	0	4	7
940	5x69	5x70	2.075	Yes	No	0	5	4
941	5x33	Lig	2.045	No	Yes	0	1	0
942	G.HG.05	G.HG.09	2.025	No	No	0	5	2
943	G.H5.18	G.h3s5.02	2.02	No	No	0	4	4
944	b.l10x2	b.l10x4	2.02	No	Yes	0	5	3
945	b.b21x7	b.l24x1	2	Yes	No	0	5	5
946	4x38	G.hns1.03	1.975	Yes	No	0	7	4
947	6x34	6x38	1.965	No	No	0	7	5
948	G.H5.05	G.H5.09	1.96	No	No	0	5	4
949	b.l8x10	b.l8x9	1.96	No	No	0	4	3
950	G.HN.51	G.hns1.01	1.95	No	No	0	5	3
951	G.s1h1.02	G.s1h1.03	1.95	No	No	0	7	8
952	b.l9x1	b.l9x2	1.95	No	No	0	5	5
953	4x63	4x64	1.945	No	Yes	0	4	4
954	7x23	7x25	1.945	No	No	0	7	3
955	G.hns1.03	I2x55	1.94	No	No	0	4	4
956	b.1x10	b.1x14	1.92	No	No	28	1	4
957	G.HN.39	G.HN.43	1.88	No	No	0	5	9
958	b.1x15	b.1x19	1.88	No	No	0	7	6
959	g.l1x2	g.l1x4	1.88	No	Yes	0	0	0
960	b.l6x1	b.l6x2	1.87	No	No	0	6	6
961	1x33	2x66	1.84	No	No	0	5	7
962	5x49	5x52	1.825	No	No	0	5	3
963	7x33	7x36	1.825	Yes	No	0	5	5
964	G.H3.01	G.s4h3.08	1.82	No	No	0	9	8
965	b.l8x3	b.l8x6	1.82	No	No	0	3	4
966	b.b12x1	b.l13x5	1.82	No	No	0	6	5
967	1x29	1x30	1.815	No	No	0	3	3
968	b.b2x2	b.b6x3	1.805	No	No	0	7	8
969	3x34	4x57	1.79	No	No	0	5	7
970	7x23	7x24	1.75	No	No	0	7	4
971	G.H1.01	G.s1h1.01	1.74	No	No	0	9	9
972	G.H1.01	G.s3h2.01	1.74	No	No	0	9	9
973	b.b18x4	b.b22x4	1.72	No	No	0	3	5
974	6x33	G.H5.25	1.71	No	No	0	8	7
975	1x54	2x44	1.71	No	No	0	7	5
976	1x57	2x44	1.71	No	No	0	7	5
977	5x62	6x34	1.7	No	No	0	6	7
978	b.b25x6	b.l25x1	1.7	No	No	0	3	3
979	G.S5.07	G.s1h1.06	1.695	No	No	0	9	9
980	b.b21x3	b.l17x2	1.64	Yes	No	0	6	6
981	b.1x15	g.h1x15	1.625	No	No	0	7	0
982	8x53	8x56	1.615	No	No	0	7	5
983	5x55	5x56	1.615	No	No	0	5	4
984	b.lhb1x4	b.lhb1x5	1.61	No	No	0	1	1
985	4x64	5x39	1.59	Yes	No	0	4	7
986	1x52	8x57	1.585	No	No	0	6	4
987	3x52	I2x53	1.58	No	No	0	4	6
988	b.1x4	g.h1x4	1.575	No	No	0	8	0
989	G.HN.36	b.b5x2	1.56	No	Yes	0	4	7
990	b.b20x7	b.l20x3	1.545	No	No	0	9	7
991	G.H1.05	G.H1.09	1.52	No	No	0	6	7
992	b.h2x4	b.h2x5	1.52	Yes	Yes	0	3	5
993	1x56	8x53	1.52	Yes	No	0	7	7
994	b.h2x3	b.lh12x3	1.515	No	No	0	1	4
995	3x24	E1x52	1.51	No	Yes	0	4	7
996	3x27	3x30	1.51	No	No	0	4	5
997	b.h2x5	g.h2x9	1.505	Yes	No	0	5	0
998	b.1x11	g.h1x8	1.49	Yes	Yes	0	8	0
999	G.s4h3.07	G.s4h3.15	1.48	No	No	0	5	9
1000	G.H1.10	G.H1.11	1.47	No	No	0	8	7
1001	b.b2x4	b.b6x4	1.46	No	No	0	6	7
1002	b.b16x1	b.l17x3	1.46	No	Yes	0	4	9
1003	G.H1.06	G.H1.10	1.455	No	No	0	9	8
1004	4x60	4x63	1.445	No	No	0	8	4
1005	b.1x15	g.h1x11	1.425	No	No	0	7	9
1006	g.ctx13	g.ctx9	1.425	No	Yes	0	9	7
1007	G.HN.11	G.HN.34	1.41	Yes	No	0	2	3
1008	b.1x11	g.h1x12	1.41	Yes	No	0	8	0
1009	b.1x12	g.h1x11	1.41	No	No	0	6	9
1010	G.HN.42	G.HN.46	1.4	No	No	0	4	4
1011	b.1x22	g.l1x4	1.395	No	Yes	0	3	0
1012	G.hgh4.02	G.hgh4.03	1.39	Yes	No	0	7	5
1013	G.HN.50	G.HN.53	1.385	No	No	0	5	1
1014	b.1x11	g.h1x11	1.385	Yes	No	0	8	9
1015	b.lhb1x3	g.h2x13	1.365	No	No	0	2	1
1016	5x68	5x71	1.36	No	No	0	6	4
1017	1x43	1x44	1.31	Yes	No	0	6	5
1018	b.l18x1	g.h3x8	1.31	Yes	No	0	6	4
1019	5x59	6x38	1.295	No	No	0	1	5
1020	6x57	7x29	1.245	No	No	0	5	4
1021	G.HG.17	G.s4h3.04	1.21	No	Yes	0	3	8
1022	1x49	7x50	1.015	No	No	0	8	9
1023	8x47	G.H5.24	0.93	No	No	0	8	8
1024	1x45	1x46	0.92	No	No	0	5	8
1025	1x48	1x49	0.92	No	No	0	4	8
1026	b.lhb1x6	b.lhb1x7	0.92	No	No	0	3	1
1027	b.l20x3	g.h2x4	0.895	No	No	0	7	0
1028	g.ctx10	g.ctx12	0.89	No	No	0	8	6
1029	G.HG.14	G.HG.16	0.875	No	No	0	5	4
1030	g.ctx1	g.h3x4	0.87	No	No	0	8	5.5
1031	6x46	6x47	0.855	No	No	0	5	8
1032	b.1x8	g.h1x8	0.85	No	Yes	0	5	0
1033	5x72	6x27	0.85	No	No	0	6	3
1034	G.H1.03	G.s6h5.03	0.84	No	No	0	9	9
1035	6x25	6x28	0.82	No	No	0	3	5
1036	b.b13x3	b.l9x2	0.82	Yes	No	0	4	5
1037	b.l21x6	b.l21x7	0.82	No	No	0	3	5
1038	b.b20x1	b.l21x5	0.81	No	No	0	5	4
1039	6x43	7x48	0.81	No	No	0	5	6
1040	b.l20x3	g.l2x4	0.805	No	No	0	7	2
1041	5x38	5x42	0.8	No	No	0	4	4
1042	G.HN.09	G.HN.11	0.795	No	Yes	0	5	2
1043	3x41	4x52	0.79	No	No	0	7	5
1044	g.ctx6	g.h2x16	0.79	No	No	0	5	0
1045	b.h2x4	g.h2x2	0.775	Yes	No	0	3	0
1046	5x73	G.H5.13	0.77	No	No	0	3	8
1047	3x22	3x23	0.77	No	No	0	3	1
1048	5x34	E2	0.77	No	Yes	0	3	3
1049	6x41	6x42	0.77	Yes	No	0	8	5
1050	6x42	6x46	0.77	No	No	0	5	5
1051	G.HG.12	G.HG.13	0.765	No	No	0	1	7
1052	2x36	G.hns1.02	0.76	Yes	No	0	7	4
1053	G.H4.13	G.H4.16	0.76	No	Yes	0	3	3
1054	5x42	5x46	0.76	No	No	0	4	4
1055	5x64	5x67	0.76	No	No	0	5	5
1056	5x72	5x75	0.76	No	No	0	6	0
1057	G.H3.04	G.s1h1.02	0.755	No	No	0	9	7
1058	b.l13x1	g.h1x6	0.75	No	No	0	2	0
1059	1x34	1x35	0.745	No	No	0	5	5
1060	1x40	1x44	0.745	No	No	0	3	5
1061	G.HN.11	G.HN.37	0.745	Yes	No	0	2	3
1062	5x63	5x67	0.74	No	No	0	5	5
1063	g.h2x14	g.h2x15	0.73	No	No	0	4	6
1064	8x52	8x53	0.715	No	No	0	5	7
1065	b.1x1	g.h1x1	0.715	No	No	0	4	0
1066	I2x56	I2x57	0.705	No	No	0	5	6
1067	g.h3x3	g.l2x5	0.705	No	No	0	5	1
1068	b.l24x3	b.lhb1x1	0.7	Yes	No	0	5	1
1069	G.H3.07	G.H3.10	0.69	No	No	0	5	5
1070	3x52	I2x56	0.69	No	No	0	4	5
1071	4x55	4x56	0.69	No	No	0	4	5
1072	G.H4.17	G.h4s6.08	0.69	No	No	0	4	3
1073	b.1x18	g.l1x4	0.69	No	Yes	0	4	0
1074	b.b25x2	b.l24x3	0.69	No	Yes	0	2	5
1075	G.S3.01	G.s2s3.02	0.68	Yes	No	0	4	3
1076	b.1x12	b.1x9	0.675	No	No	0	6	4
1077	g.h1x12	g.h1x9	0.675	No	No	0	0	0
1078	b.1x10	b.1x11	0.665	No	Yes	28	1	8
1079	b.1x11	b.1x14	0.665	Yes	No	28	8	4
1080	4x40	G.HN.48	0.66	No	No	0	4	3
1081	G.HN.42	G.HN.45	0.62	No	No	0	4	4
1082	b.1x16	b.1x20	0.62	No	No	0	4	2
1083	6x32	6x35	0.605	No	No	0	8	7
1084	b.1x2	b.1x5	0.595	No	No	0	1	3
1085	6x32	8x51	0.565	No	No	0	8	9
1086	G.H4.10	G.hgh4.04	0.56	Yes	No	0	6	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.11	2.265	4	0	2
2	G.S1.05	5.165	4	2	9
3	G.H1.08	4.71875	4	22	8
4	G.S2.05	7.31	4	2	3
5	G.S2.08	8.04375	4	15	5
6	G.S3.01	3.43	4	0	4
7	G.S3.03	8.72625	4	0	7
8	G.S3.04	7.131	5	2	6
9	G.S3.05	5.1525	4	22	7
10	G.S3.06	8.041	5	2	5
11	G.S3.07	3.34625	4	0	9
12	G.S3.08	4.5475	4	2	9
13	G.H2.03	5.87	4	2	9
14	G.H2.04	4.33375	4	0	9
15	G.H2.06	6.29417	6	2	9
16	G.H2.07	5.20312	8	2	9
17	G.h2s4.01	5.72083	6	2	9
18	G.s4h3.04	7.74917	6	11	8
19	G.H3.06	4.02375	4	16	6
20	G.H3.09	7.377	5	4	9
21	G.H3.13	4.41	4	4	5
22	G.H3.17	7.55333	6	9	5
23	G.H3.18	5.33125	4	0	9
24	G.S5.03	3.8925	4	0	8
25	G.S5.04	3.2525	4	4	9
26	G.S5.05	5.186	5	23	9
27	G.S5.06	5.83125	4	0	8
28	G.HG.04	4.94	4	0	9
29	G.hgh4.02	4.94	6	16	7
30	G.H4.03	7.216	5	4	4
31	G.H4.10	10.445	4	16	6
32	G.H4.16	5.23625	4	4	3
33	G.h4s6.02	6.25125	4	4	8
34	G.S6.01	5.9175	4	4	5
35	G.S6.05	5.38375	4	4	4
36	G.H5.08	8.94	4	15	8
37	NT	10.5673	11	1	3
38	1x39	4.964	5	1	7
39	1x43	4.70125	4	0	6
40	1x56	3.94375	4	17	7
41	2x36	4.1575	4	0	7
42	2x40	4.6025	4	6	8
43	2x42	5.403	5	0	8
44	2x50	5.161	5	0	9
45	2x57	6.225	5	1	7
46	2x60	7.97	6	1	7
47	2x64	8.486	5	1	6
48	E1x50	7.47833	6	1	9
49	E1x52	5.81625	4	1	7
50	3x28	6.18417	6	1	6
51	3x29	6.9175	4	1	5
52	3x32	5.347	5	1	7
53	3x33	5.38625	4	1	6
54	3x37	6.752	5	1	6
55	3x42	5.60125	4	0	8
56	3x50	4.245	5	14	9
57	3x51	7.1925	4	0	8
58	I2x51	5.15375	4	15	6
59	4x38	5.95	4	21	7
60	4x64	3.17	4	1	4
61	E2	17.3842	13	1	3
62	E2x52	6.0175	4	0	5
63	5x50	4.1775	4	0	9
64	5x69	2.69625	4	12	5
65	I3	5.34417	6	4	4
66	6x30	4.95875	4	12	8
67	6x37	6.48	4	14	8
68	6x41	2.695	4	0	8
69	6x48	7.212	5	1	8
70	6x51	6.97167	6	1	5
71	6x52	7.115	4	0	7
72	6x54	7.25143	7	1	5
73	6x55	7.72	5	1	6
74	E3	13.4875	6	1	3
75	7x30	7.854	5	1	4
76	7x31	8.91375	4	1	4
77	7x33	4.38125	4	1	5
78	7x34	8.309	5	1	4
79	7x38	5.7975	6	1	6
80	7x41	5.09125	4	1	7
81	7x42	6.9625	6	1	7
82	7x53	3.74	6	14	9
83	7x54	6.615	4	17	7
84	8x50	6.19125	4	17	9
85	8x54	6.724	5	17	6
86	Lig	9.04912	17	1	0
87	b.h2x4	1.86875	4	0	3
88	b.h2x5	3.758	5	0	5
89	b.lhb1x11	3.685	4	8	4
90	b.b1x3	3.81	4	10	7
91	b.b1x4	4.73875	4	0	7
92	b.b1x6	8.45	5	6	9
93	b.l1x3	7.47071	7	6	9
94	b.l1x7	4.71625	4	6	9
95	b.b2x1	6.47333	6	9	8
96	b.b2x5	6.732	5	0	7
97	b.b3x1	4.42	4	18	5
98	b.b3x2	5.3725	4	6	5
99	b.b3x4	5.095	4	6	9
100	b.l3x2	4.787	5	6	9
101	b.b4x2	5.52	4	0	8
102	b.b4x4	8.925	4	6	8
103	b.b4x5	4.63625	4	18	7
104	b.b4x6	9.675	7	6	9
105	b.l4x2	8.26875	4	10	4
106	b.b5x2	6.47625	4	0	7
107	b.b5x3	6.3	6	6	9
108	b.b5x7	7.175	4	0	7
109	b.l5x1	4.73125	4	19	8
110	b.l5x5	7.878	5	2	9
111	b.b6x5	4.9125	6	18	6
112	b.l6x5	5.847	5	3	4
113	b.b7x1	6.737	5	3	4
114	b.l7x2	4.33125	4	2	9
115	b.b8x3	4.074	5	3	6
116	b.b8x4	6.063	5	19	6
117	b.b9x3	4.845	4	0	6
118	b.l9x3	7.28167	6	3	9
119	b.l9x6	4.66	9	2	8
120	b.b10x3	4.48375	4	3	8
121	b.b10x5	4.78125	4	3	9
122	b.l10x1	4.20375	4	7	3
123	b.l10x4	5.805	4	26	3
124	b.b11x2	4.06375	4	3	7
125	b.b11x3	4.33625	4	7	5
126	b.b11x4	4.698	5	3	9
127	b.l11x2	6.5725	4	3	9
128	b.b12x6	8.507	5	3	8
129	b.b13x3	6.8275	4	3	4
130	b.b13x7	5.65167	6	7	7
131	b.l13x3	7.69	5	7	9
132	b.l13x6	5.5975	4	2	9
133	b.b14x5	3.455	4	7	5
134	b.b15x1	6.04	5	7	9
135	b.b16x4	9.65375	4	7	6
136	b.b16x5	4.5275	4	5	5
137	b.b16x6	6.55143	7	7	8
138	b.b17x7	5.963	5	5	8
139	b.l17x3	7.50143	7	5	9
140	b.b18x3	4.79375	4	5	8
141	b.b18x5	4.985	5	0	5
142	b.l18x1	6.68188	8	13	6
143	b.l18x3	6.702	5	13	5
144	b.b19x2	7.0875	6	5	6
145	b.b19x4	5.442	5	5	8
146	b.l19x1	6.39625	4	2	9
147	b.l19x2	7.0775	4	5	9
148	b.b20x2	5.633	5	5	6
149	b.b20x4	11.536	5	5	8
150	b.b20x6	6.41167	6	5	6
151	b.l20x2	3.75625	4	0	9
152	b.b21x1	7.31625	4	5	7
153	b.b21x3	8.25125	4	5	6
154	b.b21x4	5.5625	4	0	5
155	b.b21x7	5.60167	6	0	5
156	b.b22x5	7.18125	4	13	7
157	b.l22x5	7.55	4	24	9
158	b.b23x6	8.208	5	20	7
159	b.l23x1	8.36125	4	9	6
160	b.b24x3	4.12	4	8	5
161	b.b24x6	4.938	5	20	8
162	b.l24x2	4.3625	4	0	6
163	b.l24x3	3.575	4	0	5
164	b.l25x3	8.585	5	8	9
165	b.l25x6	14.4662	4	9	8
166	b.b26x3	3.979	5	8	6
167	b.l27x1	6.0575	4	25	7
168	b.l27x5	3.145	4	0	5
169	b.b27x3	6.245	4	8	8
170	b.l28x1	11.0607	7	9	9
171	b.l28x2	7.7125	4	8	9
172	b.b28x3	5.48625	4	6	7
173	b.b28x4	6.68875	4	8	6
174	b.b28x6	9.11167	6	8	9
175	b.b28x7	4.457	5	10	9
176	g.ctx2	4.458	5	10	5
177	g.ctx3	4.50375	4	0	4
178	g.ctx7	4.2475	4	10	9
179	g.ctx9	3.3775	4	0	7
180	b.1x11	1.123	5	28	8
181	g.h1x8	2.0425	4	0	0
182	g.l1x4	2.62875	4	0	0
183	g.ctx15	4.49	4	10	9
184	g.ctx16	3.74667	6	10	8
185	I1	5.48929	7	6	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b3x2	b.b4x6	13.3606	5.125	Yes	Yes	6	5	9
2	b.b2x3	b.b3x2	89.6764	4.24	No	Yes	0	6	5
3	b.b26x2	b.b2x3	89.6133	4.05	No	No	0	7	6
4	b.b26x1	b.b26x2	89.5509	3.44	No	No	0	9	7
5	b.b26x1	b.l28x1	89.4887	4.94	No	Yes	0	9	9
6	b.b2x1	b.l28x1	86.0888	5.305	Yes	Yes	9	8	9
7	b.b2x1	b.b6x1	86.1847	5.985	Yes	No	0	8	9
8	b.b6x1	b.l9x6	86.0966	4.19	No	Yes	0	9	8
9	G.H2.07	b.l9x6	75.7304	2.89	Yes	Yes	2	9	8
10	G.H2.04	G.H2.07	78.8746	3.5	Yes	Yes	0	9	9
11	G.H2.04	G.H3.08	39.5491	5.465	Yes	No	0	9	9
12	G.H3.08	G.S4.04	39.574	7.31	No	No	0	9	9
13	G.H3.09	G.S4.04	81.5449	14.465	Yes	No	0	9	9
14	G.H3.09	G.H3.13	31.1607	5.585	Yes	Yes	4	9	5
15	G.H3.13	G.h4s6.02	30.7448	3.935	Yes	Yes	4	5	8
16	G.h4s6.02	G.h4s6.08	65.8483	9.095	Yes	No	4	8	3
17	G.h4s6.08	I3	64.9146	8.4	No	Yes	4	3	4
18	6x26	I3	62.4121	11.275	No	Yes	4	5	4
19	6x26	G.h4s6.12	61.9493	8.14	No	No	0	5	4
20	G.S6.02	G.h4s6.12	44.3944	16.27	No	No	0	7	4
21	G.H5.10	G.S6.02	46.6188	4.005	No	No	0	6	7
22	G.H5.10	G.S5.03	46.0078	4.87	No	Yes	0	6	8
23	G.S4.03	G.S5.03	33.7528	3.68	No	Yes	0	7	8
24	G.S1.06	G.S4.03	32.5236	5.705	No	No	0	8	7
25	G.S1.06	G.S3.05	27.1237	4.945	No	Yes	0	8	7
26	G.S2.06	G.S3.05	21.0853	6.845	No	Yes	22	9	7
27	G.S2.06	G.S3.03	20.4741	6.43	No	Yes	0	9	7
28	G.H5.08	G.S3.03	16.7673	7.5	Yes	Yes	0	8	7
29	G.H5.08	I2x51	15.5396	3.75	Yes	Yes	15	8	6
30	G.S3.01	I2x51	11.8325	7.305	Yes	Yes	0	4	6
31	G.H2.04	G.H3.12	39.5642	3.76	Yes	No	0	9	8
32	G.H3.12	G.S4.04	42.1118	4.395	No	No	0	8	9
33	G.H3.09	G.S6.01	31.9218	6.905	Yes	Yes	4	9	5
34	G.S6.01	G.h4s6.02	35.5229	7.08	Yes	Yes	4	5	8
35	G.S5.03	G.S5.05	11.1991	3.77	Yes	Yes	0	8	9
36	G.S5.04	G.S5.06	13.0581	3.46	Yes	Yes	0	9	8
37	G.H3.09	G.S5.04	18.0955	3.65	Yes	Yes	4	9	9
38	G.H5.17	G.H5.21	27.172	5.03	No	No	0	5	5
39	G.H5.17	G.h4s6.12	24.692	8.1	No	No	0	5	4
40	3x54	5x61	25.8963	2.945	No	No	0	8	8
41	5x61	6x37	25.9414	4.28	No	Yes	0	8	8
42	3x50	6x37	24.4201	3.035	Yes	Yes	14	9	8
43	3x50	7x53	22.8288	3.085	Yes	Yes	14	9	9
44	2x46	7x53	17.9989	3.515	No	Yes	0	9	9
45	2x46	3x42	11.0886	5.49	No	Yes	0	9	8
46	2x45	3x42	39.3063	9.685	No	Yes	0	9	8
47	2x45	4x50	40.4063	3.09	No	No	0	9	9
48	2x48	4x50	40.7853	3.99	No	No	0	6	9
49	1x54	2x48	40.861	3.46	No	No	0	7	6
50	1x54	2x44	40.9489	1.71	No	No	0	7	5
51	1x57	2x44	41.0454	1.71	No	No	0	7	5
52	1x57	2x40	41.1422	2.57	No	Yes	0	7	8
53	2x40	I1	41.3836	7.715	Yes	Yes	6	8	5
54	I1	b.l1x4	41.871	4.66	Yes	No	6	5	6
55	b.l1x4	b.l3x2	42.1668	4.07	No	Yes	6	6	9
56	b.l1x3	b.l3x2	43.7391	3.15	Yes	Yes	6	9	9
57	b.b4x6	b.l1x3	43.343	6.875	Yes	Yes	6	9	9
58	3x54	G.H5.20	25.8516	5.71	No	No	0	8	9
59	6x30	G.H5.20	25.0503	4.15	Yes	No	12	8	9
60	6x30	G.H5.26	25.1908	7.915	Yes	No	0	8	5
61	E2	Lig	10.3424	15.025	Yes	Yes	1	3	0
62	6x54	Lig	10.9432	3.645	Yes	Yes	1	5	0
63	6x51	6x54	14.5276	5.145	Yes	Yes	1	5	5
64	6x51	7x41	35.637	3.555	Yes	Yes	1	5	7
65	6x48	7x41	42.0869	9.08	Yes	Yes	1	8	7
66	3x39	6x48	44.5064	4.245	No	Yes	0	9	8
67	2x49	3x39	27.9886	5.6	No	No	0	8	9
68	2x49	3x42	28.1261	2.98	No	Yes	0	8	8
69	6x55	Lig	11.0031	7.285	Yes	Yes	1	6	0
70	6x51	6x55	14.9719	13.89	Yes	Yes	1	5	6
71	2x46	2x50	10.6973	4.07	No	Yes	0	9	9
72	g.ctx2	g.ctx7	51.0861	6.37	Yes	Yes	10	5	9
73	g.ctx2	g.h2x15	100	3.075	Yes	No	0	5	6
74	g.h2x11	g.h2x15	99.21	7.62	No	No	0	6	6
75	b.l18x3	g.h2x11	98.815	2.905	Yes	No	0	5	6
76	b.l18x1	b.l18x3	28.0166	13.29	Yes	Yes	13	6	5
77	b.b22x5	b.l18x1	25.4663	13.93	Yes	Yes	13	7	6
78	b.b22x5	b.b23x2	24.6078	9.135	Yes	No	0	7	6
79	b.b23x2	b.b24x6	24.1734	2.85	No	Yes	0	6	8
80	b.b21x7	b.b24x6	19.375	7.715	Yes	Yes	0	5	8
81	b.b21x5	b.b21x7	13.7661	9.575	No	Yes	0	4	5
82	b.b21x5	b.h2x1	12.8912	9.19	No	No	0	4	5
83	b.b28x7	g.ctx16	50.8839	3.02	Yes	Yes	10	9	8
84	b.b28x7	g.ctx2	50.0832	5.665	Yes	Yes	10	9	5
85	b.h2x1	b.h2x5	12.4679	5.16	No	Yes	0	5	5
86	b.l27x5	g.h3x1	11.3686	2.515	Yes	No	0	5	5.5
87	g.h3x1	g.l3x4	11.1495	3.22	No	No	0	5.5	9
88	b.l22x3	g.l3x4	10.4919	5.155	No	No	0	9	9
89	b.l22x3	g.ctx3	10.2563	5.155	No	Yes	0	9	4
90	b.l27x5	g.ctx15	10.4426	3.355	Yes	Yes	0	5	9
91	b.b1x6	b.b4x6	35.4287	21.07	Yes	Yes	6	9	9
92	b.b1x6	b.b5x1	55.8423	3.685	Yes	No	0	9	5
93	b.b1x4	b.b5x1	55.7839	3.88	Yes	No	0	7	5
94	b.b1x6	b.b28x5	55.8798	6.425	Yes	No	0	9	5
95	b.b1x4	b.b28x5	56.2158	4.385	Yes	No	0	7	5
96	b.b1x4	g.ctx16	62.4018	4.275	Yes	Yes	0	7	8
97	b.b1x4	g.ctx9	49.4602	6.415	Yes	Yes	0	7	7
98	g.ctx7	g.ctx9	48.7114	3.02	Yes	Yes	0	9	7
99	b.b10x1	b.l9x6	32.1126	3.18	No	Yes	0	9	8
100	b.b10x1	b.b11x5	31.9112	4.075	No	No	0	9	6
101	b.b11x5	b.b14x3	27.7708	4.505	No	No	0	6	5
102	b.b11x3	b.b14x3	13.4629	6.705	Yes	No	7	5	5
103	b.b11x3	b.b14x5	11.3228	2.98	Yes	Yes	7	5	5
104	b.b10x4	b.b14x5	22.3737	3.645	No	Yes	0	6	5
105	b.b14x3	b.b15x1	14.1052	7.305	No	Yes	7	5	9
106	b.b14x5	b.b15x1	11.4579	3.045	Yes	Yes	7	5	9
107	b.b10x2	b.b10x4	21.0981	5.57	No	No	0	6	6
108	b.b10x2	b.b6x2	19.3844	3.38	No	No	0	6	8
109	b.b10x3	b.b6x2	18.9556	5.07	Yes	No	0	8	8
110	b.l18x3	b.l18x4	68.3619	2.545	Yes	No	0	5	7
111	b.b18x5	b.l18x4	67.5283	3.765	Yes	No	0	5	7
112	b.b15x2	b.b18x5	34.4467	5.895	No	Yes	0	6	5
113	b.b15x2	b.b19x2	27.5594	12.455	No	Yes	5	6	6
114	b.b18x3	b.b19x4	12.067	4.56	Yes	Yes	5	8	8
115	b.b18x5	b.l20x1	24.5237	3.045	Yes	No	0	5	6
116	b.b16x5	b.l20x1	24.0993	8.305	Yes	No	0	5	6
117	b.b17x7	b.b19x2	10.7751	6.43	Yes	Yes	5	8	6
118	b.b16x5	b.b17x7	10.7887	3.045	Yes	Yes	5	5	8
119	b.b16x5	b.b17x5	10.7683	3.995	Yes	No	5	5	7
120	b.b17x7	b.b21x1	20.737	5.375	Yes	Yes	5	8	7
121	b.b17x5	b.b21x1	10.339	14.36	No	Yes	5	7	7
122	b.b19x4	b.l17x3	14.2223	8.9	Yes	Yes	5	8	9
123	b.1x19	b.b21x1	24.8264	2.98	No	Yes	0	6	7
124	b.1x15	b.1x19	19.8141	1.88	No	No	0	7	6
125	b.1x15	g.h1x11	17.3373	1.425	No	No	0	7	9
126	b.1x11	g.h1x11	13.6222	1.385	Yes	No	0	8	9
127	g.ctx15	g.ctx16	10.246	5.78	Yes	Yes	10	9	8
128	G.H5.21	G.H5.26	25.8534	5.58	No	No	0	5	5
129	2x50	3x39	16.7098	5.06	Yes	No	0	9	9
130	b.b1x6	b.b3x2	76.1266	4.15	Yes	Yes	6	9	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
E2	NT	15.485	1	Yes	Yes	3	3	1	1
E1	NT	30.405	1	No	Yes	5	3	1	1
NT	NT	11.045	1	Yes	Yes	3	3	1	1
7x27	NT	6.365	1	No	Yes	3	3	1	1
Lig	NT	7.62	1	Yes	Yes	0	3	0	1
7x28	NT	6.175	0	No	Yes	3	3	2	1
7x31	NT	11.075	1	Yes	Yes	4	3	1	1
1x32	NT	6.76	1	No	Yes	5	3	2	1
7x32	NT	6.24	1	No	Yes	1	3	2	1
1x30	NT	4.025	1	No	Yes	3	3	2	1
2x60	2x64	13.405	1	Yes	Yes	7	6	2	1
2x60	3x28	5.05	1	Yes	Yes	7	6	2	2
2x60	7x34	7.855	1	Yes	Yes	7	4	2	1
2x60	7x38	7.885	1	Yes	Yes	7	6	2	2
2x64	3x28	6.705	1	Yes	Yes	6	6	1	2
2x64	3x29	4.645	1	Yes	Yes	6	5	1	1
2x64	7x34	8.255	1	Yes	Yes	6	4	1	1
2x64	Lig	9.42	1	Yes	Yes	6	0	1	0
E1	E1x49	5.34	1	No	No	5	5	1	2
E1	Lig	7.745	1	No	Yes	5	0	1	0
E1x49	E2	4.06	1	No	Yes	5	3	2	1
E1x50	E2	6.83	1	Yes	Yes	9	3	2	1
3x22	E2	6.31	1	No	Yes	3	3	2	1
3x26	E2	3.75	1	No	Yes	7	3	2	1
3x28	3x29	9.93	1	Yes	Yes	6	5	2	1
3x29	4x65	9.58	1	Yes	No	5	5	1	2
3x29	Lig	3.515	1	Yes	Yes	5	0	1	0
4x64	4x65	4.52	1	Yes	No	4	5	2	2
4x64	E2	4.625	1	Yes	Yes	4	3	2	1
4x65	E2x52	9.225	0	No	Yes	5	5	2	2
E2	E2	71.865	1	Yes	Yes	3	3	1	1
E2	E2x51	14.075	1	Yes	No	3	3	1	2
E2	Lig	15.025	1	Yes	Yes	3	0	1	0
E2x51	E2x52	6.12	1	No	Yes	3	5	2	2
5x36	E2x52	5.115	1	No	Yes	5	5	2	2
6x58	E2x52	3.61	1	No	Yes	3	5	1	2
5x35	E2	8.31	0	No	Yes	4	3	2	1
5x36	E2	3.025	1	No	Yes	5	3	2	1
5x40	6x55	3.13	1	No	Yes	5	6	1	1
5x40	6x59	6.545	1	No	No	5	4	1	2
5x43	6x55	8.435	1	No	Yes	5	6	2	1
6x51	6x54	5.145	1	Yes	Yes	5	5	2	1
6x51	6x55	13.89	1	Yes	Yes	5	6	2	1
6x54	6x55	5.86	1	Yes	Yes	5	6	1	1
6x54	7x30	12.35	1	Yes	Yes	5	4	1	1
6x54	7x33	4.81	1	Yes	Yes	5	5	1	2
6x54	7x34	11.835	1	Yes	Yes	5	4	1	1
6x54	7x37	7.115	1	Yes	No	5	5	1	2
6x54	Lig	3.645	1	Yes	Yes	5	0	1	0
6x55	Lig	7.285	1	Yes	Yes	6	0	1	0
6x58	7x30	6.19	1	No	Yes	3	4	1	1
6x58	Lig	12.425	1	No	Yes	3	0	1	0
6x61	E3	23.2	0	No	Yes	3	3	2	1
E3	E3	12.5	1	Yes	Yes	3	3	1	1
E3	Lig	23.125	1	Yes	Yes	3	0	1	0
7x26	E3	2.85	1	No	Yes	2	3	2	1
7x30	E3	6.75	1	Yes	Yes	4	3	1	1
7x27	7x31	17.175	1	No	Yes	3	4	1	1
7x27	Lig	20.715	1	No	Yes	3	0	1	0
7x30	7x31	4.355	1	Yes	Yes	4	4	1	1
7x30	Lig	9.625	1	Yes	Yes	4	0	1	0
7x31	Lig	3.05	1	Yes	Yes	4	0	1	0
7x33	7x37	7.78	1	Yes	No	5	5	2	2
7x34	7x38	6.4	1	Yes	Yes	4	6	1	2
7x34	Lig	7.2	1	Yes	Yes	4	0	1	0
3x22	3x26	7.145	1	No	No	3	7	2	2
5x40	Lig	2.855	1	No	Yes	5	0	1	0
6x51	7x38	2.905	1	Yes	Yes	5	6	2	2
5x33	Lig	2.045	0	No	Yes	1	0	1	0
5x34	E2	0.77	0	No	Yes	3	3	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
87.50	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
86.67	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
86.67	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
86.67	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
86.67	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
81.25	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
81.25	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
81.25	Consensus	nts_on	Orthosteric Ligand	nts1_on
77.78	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
76.47	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
76.47	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
75.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
75.00	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
73.33	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
70.59	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
70.59	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
70.59	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
70.59	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
70.59	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
68.75	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
62.50	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
61.11	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
60.00	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
58.82	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
58.82	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
56.25	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
55.56	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
55.00	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
50.00	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
50.00	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
50.00	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
50.00	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
47.83	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
47.62	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
47.62	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
45.00	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
45.00	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
45.00	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
45.00	Consensus	nts_off	Orthosteric Ligand	nts1_off
43.75	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
43.75	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
41.67	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
41.67	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
41.38	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
41.18	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
40.91	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
40.00	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
40.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
40.00	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
40.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
40.00	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
40.00	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
39.29	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
39.29	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
39.29	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
39.13	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
38.89	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
38.89	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
38.89	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
38.89	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
38.89	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
38.71	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
38.71	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
38.46	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
38.46	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
38.46	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
38.46	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
38.46	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
38.10	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
38.10	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
38.10	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
38.10	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
38.10	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
37.93	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
37.50	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
37.50	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
37.04	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
37.04	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
37.04	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
37.04	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
36.84	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
36.84	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
36.84	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
36.84	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
36.84	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
36.84	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
36.84	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
36.84	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
36.36	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
36.36	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
36.36	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.00	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
36.00	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.00	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
36.00	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
36.00	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.00	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
35.71	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
35.71	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
35.29	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
35.00	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
35.00	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
35.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
34.78	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
34.78	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
34.78	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
34.78	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.78	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.62	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
34.48	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
34.48	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
34.38	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
34.38	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
33.33	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
33.33	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
33.33	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
33.33	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
33.33	Single	6OS1	TRV026	6OS1-AT₁-TRV026
33.33	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
33.33	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
33.33	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
33.33	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
33.33	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
33.33	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
33.33	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
33.33	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
33.33	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
33.33	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
33.33	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
33.33	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.14	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
32.14	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
32.14	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
32.14	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.14	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.14	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
32.14	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
32.14	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
32.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
32.00	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
32.00	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
32.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
32.00	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
32.00	Consensus	sst_off	Orthosteric Ligand	sst2_off
31.82	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
31.82	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
31.82	Single	6OS2	TRV026	6OS2-AT₁-TRV026
31.82	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
31.58	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
31.58	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
31.58	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
31.58	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
31.58	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
31.58	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
31.25	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
30.77	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
30.77	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
30.43	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
30.43	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
30.43	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
30.43	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
30.00	Single	3EML	ZM241385	3EML-A_2A-ZM241385
30.00	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
30.00	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
30.00	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
30.00	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
30.00	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
30.00	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
30.00	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
30.00	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
30.00	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
30.00	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
30.00	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
30.00	Consensus	cck_off	Orthosteric Ligand	ccka_off
30.00	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
30.00	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
30.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
29.63	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
29.63	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
29.63	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
29.63	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
29.63	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
29.63	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.41	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
29.17	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
29.17	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.17	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
29.17	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
29.17	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
29.17	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
29.17	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
29.17	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
29.17	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
29.17	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
29.17	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
28.57	Single	5N2S	PSB36	5N2S-A₁-PSB36
28.57	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
28.57	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
28.57	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
28.57	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
28.57	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
28.57	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
28.57	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
28.57	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
28.57	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
28.57	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
28.57	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
28.57	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
28.57	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
28.57	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
28.57	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
28.57	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
28.57	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
28.57	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
28.57	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
28.57	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
28.57	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.12	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
28.12	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
28.00	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
28.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
28.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
28.00	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
28.00	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.00	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
27.78	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
27.78	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
27.78	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
27.78	Consensus	go_protein	Orthosteric Ligand	go_chemokine
27.59	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
27.59	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
27.59	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.59	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
27.27	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
27.27	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
27.27	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
27.27	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
27.27	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
27.27	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.27	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
27.27	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
27.27	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
27.27	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
27.27	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
27.27	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
27.27	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.27	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
27.27	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
27.27	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
27.27	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
26.92	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
26.92	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
26.92	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
26.92	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.92	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
26.92	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
26.92	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
26.92	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
26.92	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
26.67	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
26.67	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
26.67	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
26.67	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
26.67	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
26.67	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
26.47	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
26.32	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
26.32	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
26.32	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
26.32	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
26.32	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
26.32	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
26.32	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
26.32	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
26.32	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
26.32	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
26.32	Consensus	class-f_off	Orthosteric Ligand	smo_off
26.32	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
26.32	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
26.32	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
26.09	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
26.09	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
26.09	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
26.09	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
26.09	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
26.09	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
26.09	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
26.09	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
26.09	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
26.09	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
26.09	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
25.93	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
25.93	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
25.93	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
25.93	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
25.93	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
25.93	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
25.93	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
25.93	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
25.93	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
25.93	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
25.81	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
25.81	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
25.81	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
25.00	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
25.00	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
25.00	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
25.00	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
25.00	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
25.00	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
25.00	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
25.00	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
25.00	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
25.00	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
25.00	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
25.00	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
25.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
25.00	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
25.00	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
25.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
25.00	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
25.00	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
25.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
25.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
25.00	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
25.00	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
25.00	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
25.00	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
25.00	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
25.00	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	orexin_on	Orthosteric Ligand	ox2_on
24.24	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
24.14	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
24.14	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
24.14	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
24.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.00	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
24.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.00	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
24.00	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
24.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
24.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
24.00	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
24.00	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
24.00	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
24.00	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
24.00	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
24.00	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
24.00	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
24.00	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
24.00	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
23.81	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
23.81	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
23.81	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
23.81	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
23.81	Single	5UEN	DU172	5UEN-A₁-DU172
23.81	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
23.81	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
23.81	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
23.81	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
23.81	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
23.81	Consensus	a2_off	Orthosteric Ligand	a2a_off
23.81	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
23.81	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
23.81	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
23.81	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
23.53	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
23.33	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
23.33	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
23.33	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
23.08	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
23.08	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
23.08	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
23.08	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
23.08	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
23.08	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
23.08	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
23.08	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
23.08	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
23.08	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
23.08	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
22.73	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
22.73	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
22.73	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
22.73	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
22.73	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
22.73	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
22.73	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
22.58	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
22.22	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
22.22	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
22.22	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
22.22	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
22.22	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
22.22	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
22.22	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
22.22	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
22.22	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
21.88	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
21.88	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
21.88	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
21.88	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
21.74	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
21.74	Single	5V56	TC114	5V56-SMO-TC114
21.74	Single	5XRA	AM11542	5XRA-CB₁-AM11542
21.74	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
21.74	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
21.74	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
21.74	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
21.74	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
21.74	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
21.74	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
21.74	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
21.74	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
21.74	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
21.74	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
21.74	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
21.74	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
21.74	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
21.74	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
21.74	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
21.74	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
21.74	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
21.74	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
21.62	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
21.43	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
21.43	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
21.43	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
21.43	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
21.43	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
21.43	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
21.43	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
21.43	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
21.43	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
21.43	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
21.21	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
21.05	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
21.05	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.05	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
21.05	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
21.05	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
20.83	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
20.83	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
20.83	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
20.83	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
20.83	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
20.83	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
20.83	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
20.83	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
20.83	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
20.83	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
20.83	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
20.83	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
20.83	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
20.83	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
20.83	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
20.69	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
20.69	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
20.69	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
20.69	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
20.59	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
20.00	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
20.00	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
20.00	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
20.00	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
20.00	Single	7EZC	UKA	7EZC-A_2A-UKA
20.00	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
20.00	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
20.00	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
20.00	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
20.00	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
20.00	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
20.00	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
20.00	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
20.00	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
20.00	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
20.00	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
20.00	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
20.00	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
20.00	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
20.00	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
20.00	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
20.00	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
20.00	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
20.00	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
20.00	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
19.51	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
19.44	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
19.35	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
19.35	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
19.35	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
19.35	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
19.23	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
19.23	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
19.23	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
19.23	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
19.23	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
19.23	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
19.23	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
19.23	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
19.05	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
19.05	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
19.05	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
19.05	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.05	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
19.05	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
19.05	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
19.05	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
19.05	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.05	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
19.05	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
19.05	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
19.05	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.05	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
18.92	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
18.75	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
18.75	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
18.75	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
18.75	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
18.52	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
18.52	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
18.52	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
18.52	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
18.52	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
18.52	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
18.52	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
18.52	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
18.52	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
18.52	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
18.52	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
18.18	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
18.18	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
18.18	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
18.18	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
18.18	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
18.18	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
18.18	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
18.18	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
18.18	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
18.18	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
18.18	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
18.18	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
18.18	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
18.18	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
18.18	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
18.18	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
17.95	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
17.86	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
17.86	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
17.86	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
17.86	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
17.86	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
17.65	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
17.65	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
17.65	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
17.50	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
17.39	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
17.39	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
17.39	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
17.39	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
17.39	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
17.39	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
17.39	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
17.39	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
17.39	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
17.39	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
17.39	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
17.39	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
17.39	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
17.39	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
17.39	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
17.39	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
17.39	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
17.39	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
17.24	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
17.24	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
17.24	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
17.14	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
17.14	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
17.14	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
16.67	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
16.67	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
16.67	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
16.67	Single	5V57	TC114	5V57-SMO-TC114
16.67	Single	5XR8	AM841	5XR8-CB₁-AM841
16.67	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
16.67	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
16.67	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
16.67	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
16.67	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
16.67	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
16.67	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
16.67	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
16.67	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
16.67	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
16.67	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
16.67	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
16.67	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
16.67	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
16.67	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
16.67	Single	8E0G	BU72	8E0G-μ-BU72
16.67	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
16.67	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
16.67	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
16.67	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
16.67	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
16.67	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
16.67	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
16.67	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
16.67	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
16.67	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
16.67	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
16.67	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
16.22	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
16.22	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
16.22	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
16.22	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
16.13	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
16.13	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
16.13	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
16.13	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.00	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
16.00	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
16.00	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
16.00	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
16.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
16.00	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.00	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
16.00	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
16.00	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
16.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
16.00	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
16.00	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
16.00	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
16.00	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
16.00	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
16.00	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
16.00	Consensus	dp_off	Orthosteric Ligand	dp2_off
16.00	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
16.00	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
16.00	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
16.00	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.00	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
16.00	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
16.00	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
16.00	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
15.79	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
15.79	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
15.79	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
15.79	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
15.79	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
15.79	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
15.79	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
15.79	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
15.62	Single	6FJ3	PTH	6FJ3-PTH1-PTH
15.62	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
15.62	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
15.62	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
15.62	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
15.62	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
15.38	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
15.38	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
15.38	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
15.38	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
15.38	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
15.38	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
15.38	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
15.38	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
15.38	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
15.38	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
15.38	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
15.38	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
15.38	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
15.38	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.38	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
15.38	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
15.38	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
15.38	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
15.38	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.38	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
15.15	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
15.15	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
15.15	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
15.15	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.15	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
15.15	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
15.15	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
15.00	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
15.00	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
15.00	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
15.00	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
15.00	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
15.00	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
15.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
15.00	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
15.00	Consensus	class-t_on	Orthosteric Ligand	taste2_on
15.00	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
15.00	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
15.00	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
15.00	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
15.00	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
15.00	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
14.81	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
14.81	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
14.81	Single	6PT3	DPI-287	6PT3-δ-DPI-287
14.81	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
14.81	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
14.81	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
14.81	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
14.81	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
14.81	Consensus	class-d_off	Orthosteric Ligand	ste2_off
14.81	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
14.81	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
14.71	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
14.71	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
14.71	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
14.71	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
14.71	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
14.71	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
14.71	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
14.71	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
14.71	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
14.63	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
14.29	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
14.29	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
14.29	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
14.29	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
14.29	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
14.29	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
14.29	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
14.29	Single	7QA8	Peptide	7QA8-STE2-Peptide
14.29	Single	7QA8	Peptide	7QA8-STE2-Peptide
14.29	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
14.29	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
14.29	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
14.29	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
14.29	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
14.29	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
14.29	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
14.29	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
14.29	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
14.29	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
14.29	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
14.29	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
14.29	Consensus	class-d_off	Orthosteric Ligand	ste2_off
14.29	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
14.29	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
14.29	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
14.29	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
13.95	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
13.89	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
13.89	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
13.89	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
13.79	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
13.79	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
13.79	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
13.64	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
13.64	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
13.64	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
13.64	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
13.64	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
13.64	Single	6TPK	Retosiban	6TPK-OT-Retosiban
13.64	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
13.64	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
13.64	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
13.64	Single	7T32	ZM241385	7T32-A_2A-ZM241385
13.64	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
13.64	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
13.64	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
13.64	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
13.64	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
13.64	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
13.64	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
13.64	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
13.64	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
13.64	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
13.64	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
13.64	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
13.51	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
13.51	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
13.51	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
13.51	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
13.33	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
13.33	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
13.16	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
13.16	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
13.04	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
13.04	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
13.04	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
13.04	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
13.04	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
13.04	Single	6D27	CAY10471	6D27-DP₂-CAY10471
13.04	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
13.04	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
13.04	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
13.04	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
13.04	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
13.04	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
13.04	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
13.04	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
13.04	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
13.04	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
13.04	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
13.04	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
13.04	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
13.04	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
13.04	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
13.04	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.04	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
13.04	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
13.04	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
13.04	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
12.90	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
12.90	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
12.90	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
12.90	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.90	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
12.90	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
12.90	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
12.90	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
12.82	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
12.82	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
12.50	Single	5C1M	BU72	5C1M-μ-BU72
12.50	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
12.50	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
12.50	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
12.50	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
12.50	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
12.50	Single	7C4S	S1P	7C4S-S1P₃-S1P
12.50	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
12.50	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
12.50	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
12.50	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
12.50	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
12.50	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
12.50	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
12.50	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
12.50	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
12.50	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
12.50	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
12.50	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
12.50	Single	8HS2	Fab046	8HS2-GPR20-Fab046
12.50	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
12.50	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
12.50	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
12.50	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.50	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
12.50	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
12.50	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
12.50	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
12.50	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
12.12	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
12.12	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
12.12	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
12.12	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
12.12	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
12.12	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
12.12	Consensus	class-d_on	Orthosteric Ligand	ste2_on
12.00	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
12.00	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
12.00	Single	6E59	L-760735	6E59-NK₁-L-760735
12.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
12.00	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
12.00	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
12.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
12.00	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
12.00	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
12.00	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
12.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
12.00	Single	7W41	PD176252	7W41-BB₂-PD176252
12.00	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
12.00	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
12.00	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
12.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
12.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
12.00	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
12.00	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
12.00	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
12.00	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
12.00	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
12.00	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
11.90	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
11.76	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
11.76	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
11.76	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
11.76	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
11.76	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
11.76	Consensus	go_class-b1	Orthosteric Ligand	go_crf
11.76	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
11.76	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
11.76	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
11.63	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
11.54	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
11.54	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
11.54	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
11.54	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
11.54	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
11.54	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
11.54	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.54	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
11.54	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
11.54	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
11.54	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
11.54	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
11.54	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
11.54	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
11.54	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
11.54	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
11.54	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
11.54	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
11.43	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
11.43	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
11.43	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
11.43	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
11.43	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
11.43	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
11.11	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
11.11	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
11.11	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
11.11	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
11.11	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
11.11	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
11.11	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
11.11	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
11.11	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
11.11	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
11.11	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
11.11	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
11.11	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
11.11	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
11.11	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
11.11	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
11.11	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
10.71	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
10.71	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
10.71	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
10.71	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
10.53	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
10.53	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
10.34	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
10.34	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
10.34	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
10.34	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
10.26	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
10.00	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
10.00	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
10.00	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
10.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
10.00	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
10.00	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
10.00	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
10.00	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
10.00	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
10.00	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
10.00	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
9.52	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
9.52	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
9.52	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
9.52	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
9.52	Single	6HLL	CP99994	6HLL-NK₁-CP99994
9.52	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
9.52	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
9.52	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
9.52	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
9.52	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
9.52	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
9.52	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
9.52	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
9.52	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
9.52	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
9.52	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
9.52	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
9.52	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
9.52	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
9.52	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
9.52	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
9.52	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
9.38	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
9.38	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
9.38	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
9.38	Consensus	class-d_on	Orthosteric Ligand	ste2_on
9.38	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
9.38	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
9.38	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
9.09	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
9.09	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
9.09	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
9.09	Single	5U09	Taranabant	5U09-CB₁-Taranabant
9.09	Single	5WS3	EMPA	5WS3-OX₂-EMPA
9.09	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
9.09	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
9.09	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
9.09	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
9.09	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
9.09	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
9.09	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
9.09	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
9.09	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
9.09	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
9.09	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
9.09	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
9.09	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
9.09	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
9.09	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
9.09	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.09	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
9.09	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
9.09	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
9.09	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
9.09	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
9.09	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
9.09	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
9.09	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
9.09	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
9.09	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
8.82	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
8.70	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
8.70	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
8.70	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
8.70	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
8.70	Single	6IQL	L745870	6IQL-D₄-L745870
8.70	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
8.70	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
8.70	Single	6TPG	EMPA	6TPG-OX₂-EMPA
8.70	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
8.70	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
8.70	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
8.70	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
8.70	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
8.70	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
8.70	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
8.70	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
8.70	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
8.70	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
8.70	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.70	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.70	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
8.70	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
8.70	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
8.70	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
8.70	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
8.70	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.70	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
8.70	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
8.70	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
8.70	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
8.70	Consensus	hcar_on	Orthosteric Ligand	hca_on
8.70	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
8.70	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
8.70	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
8.57	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
8.33	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
8.33	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
8.33	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
8.33	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
8.33	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
8.33	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
8.33	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
8.33	Single	6IIV	Daltroban	6IIV-TP-Daltroban
8.33	Single	6PS1	Timolol	6PS1-β₂-Timolol
8.33	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
8.33	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
8.33	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
8.33	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
8.33	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
8.33	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
8.33	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
8.33	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
8.33	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
8.33	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
8.33	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
8.33	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
8.33	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
8.33	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
8.33	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
8.33	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
8.33	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
8.33	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
8.33	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
8.33	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
8.33	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
8.33	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
8.33	Consensus	hcar_off	Orthosteric Ligand	succinate_off
8.33	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
8.33	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
8.33	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
8.33	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
8.11	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
8.00	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
8.00	Single	5WQC	EMPA	5WQC-OX₂-EMPA
8.00	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
8.00	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
8.00	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
8.00	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
8.00	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
8.00	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
8.00	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
8.00	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
8.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
8.00	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
8.00	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
8.00	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
8.00	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
8.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
8.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
8.00	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
8.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.00	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
8.00	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
8.00	Consensus	ep_off	Orthosteric Ligand	ep4_off
7.69	Single	2YDV	NECA	2YDV-A_2A-NECA
7.69	Single	3P0G	BI167107	3P0G-β₂-BI167107
7.69	Single	4DJH	JDTic	4DJH-κ-JDTic
7.69	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
7.69	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
7.69	Single	5G53	NECA	5G53-A_2A-NECA-Gs
7.69	Single	5X93	K-8794	5X93-ET_B-K-8794
7.69	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
7.69	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
7.69	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
7.69	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
7.69	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
7.69	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
7.69	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
7.69	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
7.69	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
7.69	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
7.69	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
7.69	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
7.69	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
7.69	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
7.69	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
7.69	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
7.69	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
7.69	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
7.69	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
7.69	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
7.69	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
7.69	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
7.69	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
7.69	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
7.69	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
7.69	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
7.41	Single	4LDE	BI167107	4LDE-β₂-BI167107
7.41	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
7.41	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
7.41	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
7.41	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
7.41	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
7.41	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
7.41	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
7.41	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
7.41	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
7.41	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
7.41	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
7.41	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
7.41	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
7.41	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
7.41	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
7.41	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
7.41	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
7.41	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
7.41	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
7.41	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
7.41	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
7.41	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
7.41	Consensus	blt_off	Orthosteric Ligand	blt1_off
7.41	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
7.41	Consensus	gi_class-f	Other Ligand	gi_frizzled
7.41	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
7.41	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
7.14	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
7.14	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
7.14	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
7.14	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
7.14	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
7.14	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
7.14	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
7.14	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
7.14	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
7.14	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
7.14	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
7.14	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
7.14	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
7.14	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
7.14	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
7.14	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.14	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
7.14	Consensus	endothelin_off	Orthosteric Ligand	etb_off
7.14	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
7.14	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
7.14	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
7.14	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
6.90	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
6.90	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
6.90	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
6.67	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
6.67	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
6.67	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
6.67	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
6.67	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
6.67	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
6.67	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
6.67	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
6.67	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
6.67	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
6.67	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
6.67	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
6.67	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
6.67	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
6.67	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
6.67	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
6.67	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
6.67	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
6.67	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
6.67	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
6.67	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
6.67	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
6.67	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
6.67	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
6.67	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
6.67	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
6.67	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
6.67	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
6.67	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
6.67	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Single	7FII	hCG	7FII-LH-hCG-6fuf
6.67	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
6.67	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
6.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.67	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
6.67	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
6.67	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
6.67	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
6.67	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
6.67	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
6.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
6.67	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
6.67	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
6.67	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
6.67	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
6.67	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
6.67	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
6.67	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
6.67	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
6.67	Single	7XW7	K1-70	7XW7-TSH-K1-70
6.67	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
6.67	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
6.67	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
6.67	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
6.67	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
6.67	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
6.67	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
6.67	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
6.67	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
6.67	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
6.67	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
6.67	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
6.67	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
6.67	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
6.67	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
6.67	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
6.67	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
6.67	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
6.67	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
6.67	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
6.67	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
6.67	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
6.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
6.67	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
6.67	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
6.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
6.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
6.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
6.67	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
6.67	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
6.67	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
6.67	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
6.67	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
6.67	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
6.67	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
6.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
6.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
6.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.67	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
6.67	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
6.67	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
6.67	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
6.67	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
6.67	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
6.67	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
6.67	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
6.67	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
6.67	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
6.67	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
6.67	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
6.67	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
6.67	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
6.67	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
6.67	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
6.67	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
6.67	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
6.67	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
6.67	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.67	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
6.67	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
6.67	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
6.67	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
6.67	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
6.67	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
6.67	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
6.67	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
6.67	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
6.67	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
6.67	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
6.67	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
6.25	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
6.25	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
6.25	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
6.25	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
6.06	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
5.88	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
5.88	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
5.56	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
5.56	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
5.56	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
5.56	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
5.56	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
5.56	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
5.56	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
5.56	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
5.56	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.56	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
5.56	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
5.26	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
5.26	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
5.26	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
5.26	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
5.00	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
5.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.00	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
5.00	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
5.00	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
4.76	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
4.76	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
4.76	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
4.76	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
4.76	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
4.76	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
4.76	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
4.76	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
4.76	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
4.76	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
4.76	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
4.76	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
4.76	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
4.76	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
4.76	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
4.55	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
4.55	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
4.55	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
4.55	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
4.55	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.55	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.55	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
4.55	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
4.55	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
4.55	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
4.55	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
4.55	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
4.55	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
4.55	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
4.35	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
4.35	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
4.35	Single	6AKX	A4R	6AKX-CCR5-A4R
4.35	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
4.35	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
4.35	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
4.35	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
4.35	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
4.35	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
4.35	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.35	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
4.35	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
4.35	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
4.35	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
4.35	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
4.35	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.35	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
4.35	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
4.35	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.35	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.35	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.35	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.35	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.35	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
4.35	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
4.35	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
4.35	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
4.35	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
4.35	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.35	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
4.35	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
4.35	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
4.35	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
4.35	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.17	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
4.17	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
4.17	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
4.17	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
4.17	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
4.17	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
4.17	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
4.17	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
4.17	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
4.17	Single	6VI4	JDTic	6VI4-κ-JDTic
4.17	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
4.17	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
4.17	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
4.17	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
4.17	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
4.17	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
4.17	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
4.17	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
4.17	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.17	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.17	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
4.17	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
4.17	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
4.17	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
4.17	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.17	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.17	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.17	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
4.17	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
4.17	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
4.17	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
4.17	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
4.17	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
4.17	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
4.17	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.17	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.17	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
4.17	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.17	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.17	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.17	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
4.17	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
4.17	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
4.17	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
4.17	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
4.17	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
4.17	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
4.17	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
4.17	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
4.17	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
4.17	Consensus	sensory_off	Orthosteric Ligand	opsin_off
4.00	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
4.00	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
4.00	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
4.00	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
4.00	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
4.00	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
4.00	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
4.00	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
4.00	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
4.00	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
4.00	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
4.00	Single	6GPS	MK0812	6GPS-CCR2-MK0812
4.00	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
4.00	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
4.00	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
4.00	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
4.00	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
4.00	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.00	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
4.00	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
4.00	Single	7BU7	BI167107	7BU7-β₁-BI167107
4.00	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
4.00	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
4.00	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
4.00	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
4.00	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
4.00	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
4.00	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
4.00	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
4.00	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
4.00	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
4.00	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
4.00	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
4.00	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
4.00	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
4.00	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
4.00	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
4.00	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
4.00	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
4.00	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
4.00	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
4.00	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
4.00	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
4.00	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
4.00	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
4.00	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
4.00	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
4.00	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
4.00	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
4.00	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
4.00	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
4.00	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
4.00	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
4.00	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
4.00	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
4.00	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
4.00	Consensus	blt_on	Orthosteric Ligand	blt1_on
4.00	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
4.00	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
4.00	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
4.00	Consensus	leuko_on	Orthosteric Ligand	blt_on
4.00	Consensus	tar_on	Orthosteric Ligand	ta1_on
3.85	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
3.85	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
3.85	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
3.85	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
3.85	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
3.85	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
3.85	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
3.85	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
3.85	Single	6GPX	MK0812	6GPX-CCR2-MK0812
3.85	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
3.85	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
3.85	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
3.85	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
3.85	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
3.85	Single	6PS6	Timolol	6PS6-β₂-Timolol
3.85	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
3.85	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
3.85	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
3.85	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
3.85	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
3.85	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
3.85	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
3.85	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
3.85	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
3.85	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
3.85	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
3.85	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
3.85	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
3.85	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
3.85	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
3.85	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
3.85	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
3.85	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
3.85	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
3.85	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
3.85	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
3.85	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
3.85	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
3.70	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
3.70	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
3.70	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
3.70	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
3.70	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
3.70	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
3.70	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
3.70	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
3.70	Single	7EPE	NAM563	7EPE-mGlu-NAM563
3.70	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
3.70	Single	7P2L	4YI	7P2L-mGlu₅-4YI
3.70	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
3.70	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
3.70	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
3.70	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
3.70	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
3.70	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
3.70	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
3.70	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
3.70	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
3.70	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
3.70	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
3.70	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
3.70	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
3.70	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
3.70	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
3.70	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
3.70	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
3.70	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
3.70	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
3.70	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
3.70	Consensus	histamine_off	Orthosteric Ligand	h1_off
3.57	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
3.57	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
3.57	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
3.57	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
3.57	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
3.57	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
3.57	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
3.57	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
3.57	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
3.57	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
3.57	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
3.57	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
3.57	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
3.57	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
3.57	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
3.57	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
3.57	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
3.45	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
3.45	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
3.45	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
3.45	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
3.45	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.45	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.45	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.45	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.33	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
3.33	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.33	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.33	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
3.23	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol

Consensus Members
	Id	Members
	7L0P	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
	6OS9	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2

Net Summary
I_min	2.825
Number of Linked Nodes	879
Number of Links	1086
Number of Hubs	185
Number of Links mediated by Hubs	689
Number of Communities	28
Number of Nodes involved in Communities	258
Number of Links involved in Communities	392

Path Summary
Number Of Nodes in MetaPath	131
Number Of Links MetaPath	130
Number of Shortest Paths	2181873
Length Of Smallest Path	3
Average Path Length	32.1168
Length of Longest Path	59
Minimum Path Strength	0.585
Average Path Strength	5.53837
Maximum Path Strength	24.4175
Minimum Path Correlation	0.7
Average Path Correlation	0.971955
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.12766
Average % Of Corr. Nodes	32.501
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	51.5893
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gi_peptide	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download gi_neurotensin.zip

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