psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.11	G.HN.33	4.97556	Yes	No	0	2	4
2	G.HN.11	G.HN.34	2.97667	Yes	No	0	2	3
3	G.HN.30	G.HN.33	5.07	No	No	0	7	4
4	G.HN.37	G.HN.41	4.21556	No	No	0	3	4
5	G.HN.37	b.b5x2	4.59667	No	Yes	0	3	7
6	G.HN.39	G.HN.43	3.62111	No	Yes	0	5	9
7	G.HN.39	b.b5x5	3.63778	No	Yes	0	5	5
8	G.HN.40	b.b5x2	6.29111	No	Yes	0	7	7
9	G.HN.40	b.b5x3	4.42	No	Yes	0	7	9
10	G.HN.43	G.HN.47	2.85111	Yes	Yes	6	9	6
11	G.HN.43	b.b5x3	6.94667	Yes	Yes	6	9	9
12	G.HN.44	b.b5x3	10.2933	No	Yes	0	6	9
13	G.HN.47	b.b4x2	5.17	Yes	No	0	6	8
14	G.HN.47	b.b4x4	3.01222	Yes	Yes	6	6	8
15	G.HN.47	b.b5x3	3.13333	Yes	Yes	6	6	9
16	G.HN.50	b.b4x2	5.99333	No	No	0	5	8
17	G.hns1.03	I2x55	6.78444	No	No	0	4	4
18	G.S1.01	G.S2.05	3.41778	No	No	1	6	3
19	G.S1.01	G.S3.02	7.65889	No	No	1	6	4
20	G.S1.01	G.S3.04	9	No	Yes	1	6	6
21	G.S1.02	G.S3.01	3.80778	Yes	Yes	3	5	4
22	G.S1.02	G.S3.03	7.72222	Yes	Yes	3	5	7
23	G.S1.02	G.h2s4.05	4.93667	Yes	No	0	5	7
24	G.H5.11	G.S1.02	4.45222	No	Yes	3	8	5
25	G.S1.03	G.S3.06	7.02889	No	Yes	1	9	5
26	G.S1.04	G.S3.05	2.98444	No	Yes	0	7	7
27	G.S1.04	G.S4.03	5.55	No	No	0	7	7
28	G.S1.05	G.S1.07	6.91889	Yes	No	1	9	9
29	G.S1.05	G.h2s4.01	10.8256	Yes	Yes	1	9	9
30	G.S1.05	G.S4.02	3.01333	Yes	Yes	1	9	8
31	G.H1.01	G.S1.06	6.11	Yes	Yes	3	9	8
32	G.S1.06	G.S3.05	4.55222	Yes	Yes	3	8	7
33	G.S1.06	G.S3.07	4.22333	Yes	No	3	8	9
34	G.S1.06	G.S4.03	2.85	Yes	No	0	8	7
35	G.H3.12	G.S1.07	3.80444	No	No	0	8	9
36	G.H1.01	G.s1h1.01	4.26	Yes	No	0	9	9
37	G.S5.07	G.s1h1.06	3.01778	Yes	No	0	9	9
38	G.H1.02	G.H1.06	3.06	No	No	0	9	9
39	G.H1.04	G.S4.05	3.81667	No	No	3	7	7
40	G.H1.04	G.S5.07	4.09333	No	Yes	3	7	9
41	G.H1.07	G.H5.03	8.65333	No	Yes	0	9	8
42	G.H1.08	G.S2.06	8.29445	Yes	Yes	3	8	9
43	G.H1.08	G.S3.05	3.69	Yes	Yes	3	8	7
44	G.H1.08	G.H5.04	3.88667	Yes	No	0	8	7
45	G.H1.08	G.H5.07	3.21111	Yes	No	0	8	8
46	G.hfs2.07	b.l7x4	3.95889	No	No	0	9	9
47	G.S2.01	G.S3.06	3.20889	No	Yes	1	9	5
48	G.S2.01	G.S3.08	4.43778	No	No	1	9	9
49	G.S2.01	b.l5x5	8.22333	No	Yes	1	9	9
50	G.S2.03	G.S3.06	8.03333	No	Yes	1	9	5
51	G.S2.05	G.S3.02	6.37	No	No	1	3	4
52	G.S2.05	G.S3.04	8.73333	No	Yes	1	3	6
53	G.S2.06	G.S3.03	14.6467	Yes	Yes	3	9	7
54	G.S2.06	G.S3.05	4.83667	Yes	Yes	3	9	7
55	G.S2.07	G.S3.02	7.45667	No	No	0	3	4
56	G.S2.08	G.s2s3.01	11.4444	Yes	No	3	5	4
57	G.H5.04	G.S2.08	8.15556	No	Yes	0	7	5
58	G.H5.05	G.S2.08	3.51111	No	Yes	3	5	5
59	G.H5.08	G.S2.08	6.66889	Yes	Yes	3	8	5
60	G.H5.08	G.s2s3.01	7.85889	Yes	No	3	8	4
61	G.S3.01	G.S3.03	7.98444	Yes	Yes	3	4	7
62	G.H5.08	G.S3.01	5.41222	Yes	Yes	3	8	4
63	G.S3.01	I2x51	4.96556	Yes	No	0	4	7
64	G.H5.11	G.S3.03	5.09667	No	Yes	3	8	7
65	G.S3.04	G.S3.06	4.96	Yes	Yes	1	6	5
66	G.S3.06	G.h2s4.01	3.57444	Yes	Yes	1	5	9
67	G.S3.06	b.l5x5	13.3644	Yes	Yes	1	5	9
68	G.H2.07	G.S3.08	7.63	Yes	No	1	9	9
69	G.S3.08	G.h2s4.01	4.65889	No	Yes	1	9	9
70	G.H2.02	G.s3h2.03	3.20889	No	Yes	1	8	9
71	G.H2.07	G.s3h2.03	7.18	Yes	Yes	1	9	9
72	G.s3h2.03	b.l7x2	3.84333	Yes	No	1	9	9
73	G.s3h2.03	b.l7x4	2.93333	Yes	No	0	9	9
74	G.s3h2.03	b.l9x6	3.00444	Yes	Yes	1	9	8
75	G.H2.02	b.l9x6	4.66556	No	Yes	1	8	8
76	G.H2.02	b.l13x6	3.43444	No	Yes	1	8	9
77	G.H2.03	G.H2.05	6.6	Yes	No	1	9	8
78	G.H2.03	G.H2.06	3.75	Yes	Yes	1	9	9
79	G.H2.03	b.l13x6	8.80555	Yes	Yes	1	9	9
80	G.H2.04	G.H2.07	4.44444	Yes	Yes	0	9	9
81	G.H2.04	G.H2.08	4.31444	Yes	No	0	9	8
82	G.H2.04	G.H3.11	3.95444	Yes	No	0	9	7
83	G.H2.05	G.H2.06	4.94778	No	Yes	1	8	9
84	G.H2.05	b.l17x6	3.99556	No	Yes	1	8	9
85	G.H2.06	b.l9x6	3.58	Yes	Yes	1	9	8
86	G.H2.06	b.b14x1	8.64	Yes	No	1	9	8
87	G.H2.06	b.l15x1	5.03	Yes	Yes	1	9	7
88	G.H2.06	b.l17x6	8.45	Yes	Yes	1	9	9
89	G.H2.06	b.b18x1	4.19889	Yes	No	0	9	9
90	G.H2.07	G.h2s4.01	3.56333	Yes	Yes	1	9	9
91	G.H2.07	b.l7x2	5.06222	Yes	No	1	9	9
92	G.H2.07	b.l9x6	5.57444	Yes	Yes	1	9	8
93	G.H2.08	G.H3.15	2.98889	No	No	1	8	8
94	G.H2.08	G.H3.18	5.02111	No	Yes	1	8	9
95	G.H2.09	G.H3.17	8.93333	No	Yes	1	8	5
96	G.H2.09	b.b2x1	6.65444	No	Yes	1	8	8
97	G.H2.09	b.l28x1	7.40444	No	Yes	1	8	9
98	G.H2.10	b.b2x1	6.27222	No	Yes	1	7	8
99	G.H2.10	b.l3x1	3.73	No	No	1	7	9
100	G.h2s4.01	b.l5x5	10.5778	Yes	Yes	1	9	9
101	G.H3.17	G.h2s4.02	9.20556	Yes	No	0	5	7
102	G.h2s4.02	b.l1x6	6.3	No	No	0	7	9
103	G.H3.18	G.S4.02	7.53444	Yes	Yes	1	9	8
104	G.S4.02	G.h3s5.03	3.71556	Yes	No	1	8	7
105	G.S4.02	G.S5.02	3.10667	Yes	No	1	8	6
106	G.S4.03	G.S5.05	2.93	No	Yes	0	7	9
107	G.S4.04	G.S4.06	3.05667	Yes	No	0	9	7
108	G.H3.08	G.S4.04	5.54889	No	Yes	0	9	9
109	G.H3.09	G.S4.04	12.0267	Yes	Yes	1	9	9
110	G.S4.04	G.S5.04	3.38111	Yes	Yes	1	9	9
111	G.S4.05	G.S5.07	3.32444	No	Yes	3	7	9
112	G.H3.05	G.S4.06	3.77222	No	No	0	9	7
113	G.H4.15	G.S4.06	7.72111	Yes	No	0	8	7
114	G.S4.07	G.s4h3.03	3.94667	No	Yes	0	8	8
115	G.S5.06	G.s4h3.01	6.91889	No	No	0	8	7
116	G.HG.04	G.s4h3.01	11.5022	Yes	No	0	9	7
117	G.H4.11	G.s4h3.01	3.64556	No	No	0	7	7
118	G.s4h3.02	G.s5hg.01	5.44	No	No	0	9	9
119	G.HG.03	G.s4h3.02	5.67333	No	No	0	6	9
120	G.s4h3.03	G.s4h3.06	2.86667	Yes	No	23	8	8
121	G.H3.01	G.s4h3.03	12.1756	Yes	Yes	23	9	8
122	G.H3.02	G.s4h3.03	4.77444	No	Yes	0	8	8
123	G.s4h3.04	G.s4h3.05	12.0056	Yes	Yes	17	8	9
124	G.HG.04	G.s4h3.04	6.41889	Yes	Yes	0	9	8
125	G.HG.07	G.s4h3.04	5.57333	No	Yes	17	9	8
126	G.HG.13	G.s4h3.04	3.53333	No	Yes	17	7	8
127	G.HG.15	G.s4h3.04	3.51778	Yes	Yes	0	7	8
128	G.HG.07	G.s4h3.05	3.99444	No	Yes	17	9	9
129	G.HG.13	G.s4h3.05	3.43333	No	Yes	17	7	9
130	G.H3.03	G.s4h3.15	6.80222	No	No	12	4	9
131	G.hgh4.01	G.s4h3.15	4.37222	No	No	12	6	9
132	G.H3.03	G.hgh4.01	2.94889	No	No	12	4	6
133	G.H3.06	G.hgh4.02	5.45444	No	Yes	0	6	7
134	G.H3.06	G.H4.15	4.69778	No	Yes	0	6	8
135	G.H3.06	G.h4s6.01	2.98333	No	No	0	6	4
136	G.H3.09	G.H3.13	4.96667	Yes	Yes	1	9	5
137	G.H3.09	G.S5.02	5.30111	Yes	No	1	9	6
138	G.H3.09	G.S5.04	4.60333	Yes	Yes	1	9	9
139	G.H3.09	G.H4.15	5.83333	Yes	Yes	1	9	8
140	G.H3.09	G.h4s6.01	5.00667	Yes	No	0	9	4
141	G.H3.09	G.S6.01	4.18444	Yes	No	0	9	5
142	G.H3.10	G.H3.14	5.68556	No	Yes	0	5	8
143	G.H3.10	G.h4s6.01	3.46778	No	No	0	5	4
144	G.H3.12	G.H3.18	3.20889	No	Yes	0	8	9
145	G.H3.13	G.H3.14	3.32222	Yes	Yes	0	5	8
146	G.H3.13	G.S5.02	3.09	Yes	No	1	5	6
147	G.H3.13	G.h4s6.02	2.97222	Yes	No	0	5	8
148	G.H3.13	G.h4s6.11	4.49222	Yes	No	0	5	7
149	G.H3.14	G.h4s6.03	10.1033	Yes	No	0	8	5
150	G.H3.15	G.H3.17	4.77111	No	Yes	1	8	5
151	G.H3.15	G.H3.18	3.62444	No	Yes	1	8	9
152	G.H3.16	G.H3.17	14.9522	No	Yes	0	4	5
153	G.H3.17	b.l25x6	4.77778	Yes	Yes	1	5	8
154	G.H3.17	b.l28x1	4.47778	Yes	Yes	1	5	9
155	G.H3.18	G.h3s5.03	5.33333	Yes	No	1	9	7
156	G.h3s5.01	G.h3s5.02	3.37444	No	No	0	3	4
157	G.h3s5.01	G.h4s6.04	7.18667	No	No	0	3	4
158	G.H5.14	G.S5.01	5.02667	No	No	0	7	7
159	G.S5.03	G.S5.05	2.93	Yes	Yes	3	8	9
160	G.H5.06	G.S5.03	3.21	Yes	Yes	3	3	8
161	G.H5.10	G.S5.03	3.78889	No	Yes	0	6	8
162	G.S5.04	G.S5.06	4.30556	Yes	No	0	9	8
163	G.H4.15	G.S5.04	3.92444	Yes	Yes	1	8	9
164	G.S5.04	G.S6.03	4.42222	Yes	No	1	9	5
165	G.S5.05	G.s6h5.01	5.04444	Yes	Yes	3	9	9
166	G.H5.06	G.S5.05	3.33444	Yes	Yes	3	3	9
167	G.S5.06	G.S6.05	7.44555	No	No	0	8	4
168	G.S5.07	G.s6h5.01	5.03444	Yes	Yes	3	9	9
169	G.H4.03	G.HG.01	6.50222	Yes	No	0	4	5
170	G.HG.01	G.s6h5.02	5.56889	No	Yes	0	5	7
171	G.HG.02	G.s6h5.02	4.84222	No	Yes	0	9	7
172	G.HG.04	G.HG.08	6.14	Yes	No	0	9	6
173	G.H4.03	G.HG.04	3.44	Yes	Yes	0	4	9
174	G.H4.03	G.HG.05	10.1011	Yes	No	0	4	5
175	G.HG.06	G.HG.12	3.15	No	No	0	5	1
176	G.HG.14	G.HG.16	3.88667	No	No	0	5	4
177	G.HG.15	G.hgh4.02	4.03778	Yes	Yes	0	7	7
178	G.HG.15	G.hgh4.05	6.25111	Yes	Yes	0	7	7
179	G.H4.11	G.HG.15	3.64667	No	Yes	0	7	7
180	G.hgh4.01	G.hgh4.02	6.27222	No	Yes	12	6	7
181	G.H4.10	G.hgh4.02	6.73	Yes	Yes	12	6	7
182	G.H4.14	G.hgh4.02	7.51778	No	Yes	12	5	7
183	G.hgh4.05	G.hgh4.07	5.30889	Yes	No	0	7	7
184	G.H4.05	G.hgh4.05	3.36556	Yes	Yes	0	4	7
185	G.H4.10	G.hgh4.05	14.1211	Yes	Yes	0	6	7
186	G.H4.02	G.hgh4.08	3.73333	No	No	24	5	3
187	G.H4.05	G.hgh4.08	4.95	Yes	No	24	4	3
188	G.H4.02	G.H4.05	5.48889	No	Yes	24	5	4
189	G.H4.03	G.H4.04	6.60889	Yes	No	0	4	4
190	G.H4.03	G.H4.07	3.55889	Yes	No	0	4	5
191	G.H4.07	G.S6.05	3.69667	No	No	0	5	4
192	G.H4.10	G.H4.14	14.6533	Yes	No	12	6	5
193	G.H4.12	G.H4.16	5.66556	No	No	1	5	3
194	G.H4.12	G.S6.03	14.0144	No	No	1	5	5
195	G.H4.12	G.S6.05	7.41889	No	No	0	5	4
196	G.H4.16	G.S6.01	5.01	No	No	0	3	5
197	G.H4.16	G.S6.03	5.48667	No	No	1	3	5
198	G.h4s6.02	G.h4s6.08	8.23778	No	No	0	8	3
199	G.S6.01	G.h4s6.02	6.29333	No	No	0	5	8
200	G.S6.02	G.h4s6.12	14.34	Yes	No	0	7	4
201	G.H5.10	G.S6.02	5.19	No	Yes	0	6	7
202	G.H5.13	G.S6.02	9.57667	Yes	Yes	0	8	7
203	G.H5.14	G.S6.02	3.64889	No	Yes	0	7	7
204	G.S6.04	G.s6h5.01	4.10889	No	Yes	3	9	9
205	G.H5.03	G.S6.04	3.11778	Yes	No	3	8	9
206	G.H5.06	G.S6.04	20.1133	Yes	No	3	3	9
207	G.H5.03	G.s6h5.01	10.0733	Yes	Yes	3	8	9
208	G.H5.03	G.s6h5.05	6.43222	Yes	Yes	0	8	9
209	G.H5.05	I3	4.12222	No	Yes	3	5	3
210	G.H5.06	I3	5.56444	Yes	Yes	3	3	3
211	G.H5.08	G.H5.12	4.46778	Yes	No	0	8	6
212	5x71	G.H5.09	3.6	No	Yes	0	3	4
213	G.H5.09	I3	4.06222	Yes	Yes	3	4	3
214	G.H5.13	G.H5.17	11.2144	Yes	No	0	8	5
215	5x68	G.H5.13	8.54333	No	Yes	0	7	8
216	5x72	G.H5.13	4.55556	No	Yes	0	6	8
217	G.H5.15	G.H5.19	3.46333	No	No	0	7	8
218	G.H5.15	I2x51	3.20889	No	No	0	7	7
219	G.H5.16	I2x50	4.70444	No	No	0	6	8
220	5x68	G.H5.16	6.04	No	No	0	7	6
221	6x29	G.H5.17	2.84333	No	No	0	5	5
222	G.H5.19	I2x53	12.5333	No	Yes	7	8	7
223	G.H5.19	I2x54	3.26444	No	No	7	8	5
224	G.H5.20	G.H5.25	3.84444	No	No	0	9	7
225	G.H5.20	G.H5.26	8.25667	No	No	0	9	5
226	3x54	G.H5.20	3.73667	No	No	0	9	9
227	2x37	G.H5.22	6.59	No	No	7	6	4
228	G.H5.22	I2x54	4.91667	No	No	7	4	5
229	2x39	G.H5.23	3.05889	No	No	0	8	4
230	3x53	G.H5.23	3.38222	No	No	0	8	4
231	3x50	G.H5.25	12.1467	Yes	No	0	9	7
232	6x33	G.H5.25	3.23	No	No	0	7	7
233	6x29	G.H5.26	3.28556	No	No	0	5	5
234	6x32	G.H5.26	17.35	No	No	0	8	5
235	b.1x1	b.1x5	4.72444	Yes	No	0	4	3
236	b.1x2	b.1x3	4.35222	No	No	0	1	1
237	b.1x3	b.1x4	2.95556	No	No	0	1	8
238	b.1x4	g.h1x4	3.32778	No	No	0	8	5
239	b.1x4	g.h1x5	3.10111	No	No	0	8	6
240	b.1x7	g.h1x8	4.12	No	No	0	8	7
241	b.1x11	g.h1x11	3.07667	No	No	0	8	9
242	b.1x11	g.h1x12	5.01333	No	No	0	8	6
243	b.1x12	g.h1x11	3.91667	No	No	0	6	9
244	b.1x15	b.1x19	4.87222	No	Yes	0	7	6
245	b.1x15	g.h1x14	3.49222	No	No	0	7	9
246	b.1x18	g.l1x4	3.38111	No	Yes	0	4	8
247	b.1x19	b.b21x1	9.39556	Yes	Yes	0	6	7
248	b.1x19	b.b21x2	3.37444	Yes	No	0	6	6
249	b.b21x2	b.lh12x1	3.70667	No	No	0	6	3
250	b.lh12x2	g.l1x6	8.14333	No	No	0	8	4
251	b.lh12x2	g.h2x2	7.03444	No	No	0	8	9
252	b.h2x3	b.lh12x4	5.19667	No	No	0	1	3
253	b.h2x1	b.h2x5	3.44	Yes	No	0	5	5
254	b.b21x4	b.h2x1	4.30556	No	Yes	0	5	5
255	b.b21x5	b.h2x1	7.22444	Yes	Yes	0	4	5
256	b.b21x5	b.h2x2	3.06556	Yes	No	0	4	1
257	b.h2x5	b.lhb1x3	2.87111	No	No	0	5	2
258	b.h2x5	b.l24x2	6.06	No	No	0	5	6
259	b.l22x5	b.lhb1x6	4.79667	Yes	No	14	9	3
260	b.b24x7	b.lhb1x6	7.62667	No	No	14	9	3
261	b.lhb1x11	b.lhb1x9	2.91889	Yes	No	0	4	3
262	b.b23x1	b.lhb1x9	3.17111	Yes	No	0	5	3
263	b.b25x4	b.lhb1x9	3.24778	No	No	0	4	3
264	b.b25x7	b.lhb1x11	5.33778	No	Yes	0	7	4
265	b.b28x7	b.lhb1x11	2.96	Yes	Yes	0	9	4
266	b.lhb1x11	g.ctx5	4.39778	Yes	No	0	4	9
267	b.b1x1	b.b1x3	3.67333	No	No	0	5	7
268	b.b1x2	b.b28x4	8.00778	No	Yes	13	3	6
269	b.b1x2	b.b28x6	8.89333	No	Yes	13	3	9
270	b.b1x3	b.b28x7	4.02	No	Yes	9	7	9
271	b.b1x3	g.ctx16	3.68222	No	Yes	9	7	8
272	b.b1x4	b.b5x1	3.59222	Yes	No	0	7	5
273	b.b1x4	b.b28x5	5.14889	Yes	No	9	7	5
274	b.b1x4	g.ctx16	6.05778	Yes	Yes	9	7	8
275	b.b1x5	b.l1x1	7.33	No	No	0	3	7
276	b.b1x5	b.b28x4	7.17333	No	Yes	0	3	6
277	b.b1x6	b.b4x6	20.1189	Yes	Yes	0	9	9
278	b.b1x6	b.b5x1	3.11222	Yes	No	0	9	5
279	b.b1x6	b.b28x3	7.07333	Yes	Yes	0	9	7
280	b.b1x6	b.b28x5	2.85444	Yes	No	0	9	5
281	b.b28x2	b.l1x1	6.77	No	No	0	4	7
282	b.l1x3	b.l1x7	9.27889	Yes	No	0	9	9
283	b.b3x4	b.l1x3	7.90333	No	Yes	6	9	9
284	b.b3x6	b.l1x3	12.7078	No	Yes	6	9	9
285	b.l1x3	b.l3x2	3.78	Yes	Yes	6	9	9
286	b.b4x4	b.l1x3	11.9333	Yes	Yes	6	8	9
287	b.b4x6	b.l1x3	3.17444	Yes	Yes	6	9	9
288	b.l1x5	b.l3x2	3.43	No	Yes	0	7	9
289	b.b2x1	b.l1x6	8.36111	Yes	No	1	8	9
290	b.l1x6	b.l28x1	21.5322	No	Yes	1	9	9
291	b.b28x3	b.l1x7	4.43889	Yes	No	0	7	9
292	b.b2x1	b.l3x1	14.6544	Yes	No	1	8	9
293	b.b2x1	b.l28x1	9.53889	Yes	Yes	1	8	9
294	b.b2x3	b.b2x5	3.23222	No	Yes	6	6	7
295	b.b2x3	b.b3x2	4.55333	No	No	6	6	5
296	b.b26x2	b.b2x3	4.5	No	No	0	7	6
297	b.b2x4	b.b6x5	3.14889	No	Yes	0	6	6
298	b.b10x4	b.b2x4	11.16	No	No	0	6	6
299	b.b2x5	b.b3x2	10.2511	Yes	No	6	7	5
300	b.b2x5	b.l4x1	5.76444	Yes	No	0	7	5
301	b.b2x5	b.l27x1	11.9956	Yes	No	6	7	7
302	b.b27x2	b.b2x5	4.46778	No	Yes	0	5	7
303	b.b6x5	b.l2x1	4.99	Yes	No	0	6	5
304	b.l27x2	b.l2x2	3.37333	No	No	0	1	1
305	b.l2x3	b.l2x5	2.90889	No	No	0	8	5
306	b.b3x1	b.l2x3	5.73222	No	No	0	5	8
307	b.l27x1	b.l2x4	6.21667	No	No	6	7	5
308	b.l27x3	b.l2x4	8.50667	No	No	6	7	5
309	b.b4x7	b.l2x5	14.0267	No	No	0	8	5
310	b.l2x5	b.l4x2	24.8078	No	No	0	5	4
311	b.b3x1	b.b6x5	4.55778	No	Yes	0	5	6
312	b.b3x2	b.b4x6	4.93444	No	Yes	6	5	9
313	b.b3x3	b.b4x3	3.64222	Yes	Yes	8	8	7
314	b.b3x3	b.b6x3	4.74444	Yes	No	0	8	8
315	b.b3x3	b.b6x5	4.90667	Yes	Yes	8	8	6
316	b.b3x3	b.b7x2	4.63111	Yes	No	8	8	8
317	b.b3x4	b.b4x6	5.90111	No	Yes	6	9	9
318	b.b28x3	b.b3x4	4.83889	Yes	No	0	7	9
319	b.b3x5	b.b6x3	3.20889	No	No	0	9	8
320	b.b3x6	b.l3x2	8.17889	No	Yes	6	9	9
321	b.l3x1	b.l5x5	8.52	No	Yes	1	9	9
322	b.b4x2	b.l3x2	5.83889	No	Yes	0	8	9
323	b.b4x3	b.b5x7	6.97667	Yes	Yes	8	7	7
324	b.b4x3	b.l5x1	5.22889	Yes	Yes	8	7	8
325	b.b4x3	b.b7x4	5.11333	Yes	No	8	7	8
326	b.b4x4	b.b4x6	13.9622	Yes	Yes	6	8	9
327	b.b4x4	b.b5x3	6.13778	Yes	Yes	6	8	9
328	b.b4x5	b.b5x5	7.21778	No	Yes	0	7	5
329	b.b4x5	b.l8x1	3.96222	No	Yes	0	7	5
330	b.b4x6	b.b5x3	10.6978	Yes	Yes	6	9	9
331	b.b4x7	b.l4x3	6.42556	No	No	22	8	6
332	b.b4x7	b.b5x2	2.84333	No	Yes	22	8	7
333	b.l4x1	g.ctx16	5.13667	No	Yes	0	5	8
334	b.l4x2	g.ctx15	12.9811	No	Yes	9	4	9
335	b.l4x2	g.ctx16	7.22	No	Yes	9	4	8
336	b.b5x2	b.l4x3	7.79889	Yes	No	22	7	6
337	b.b5x4	b.b5x5	6.30778	No	Yes	0	5	5
338	b.b5x5	b.l8x8	5.69	Yes	Yes	0	5	4
339	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
340	b.b5x7	b.b8x4	5.64333	Yes	Yes	8	7	6
341	b.b5x7	b.l8x8	8.87444	Yes	Yes	8	7	4
342	b.l5x1	b.l5x6	3.47667	Yes	No	0	8	9
343	b.b7x4	b.l5x1	3.88	No	Yes	8	8	8
344	b.b8x4	b.l5x1	5.86	Yes	Yes	8	6	8
345	b.l5x2	b.l8x10	6.39333	Yes	No	0	6	4
346	b.b9x3	b.l5x2	8.65778	No	Yes	0	6	6
347	b.l5x3	b.l7x3	9.81556	No	No	0	8	9
348	b.l5x4	b.l5x5	4.25667	No	Yes	0	8	9
349	b.l5x5	b.l7x2	5.31445	Yes	No	1	9	9
350	b.b6x1	b.l9x6	5.72111	No	Yes	0	9	8
351	b.b10x3	b.b6x2	4.69444	Yes	No	0	8	8
352	b.b6x5	b.l6x4	4.02444	Yes	No	0	6	5
353	b.b6x5	b.b7x2	3.22444	Yes	No	8	6	8
354	b.b6x5	b.l8x1	2.99556	Yes	Yes	8	6	5
355	b.b10x5	b.l6x1	7.55222	Yes	No	0	9	6
356	b.l6x3	b.l6x5	7.94667	No	Yes	18	6	4
357	b.l10x3	b.l6x3	8.83222	No	No	18	6	6
358	b.b7x1	b.l6x5	2.97333	Yes	Yes	18	4	4
359	b.l6x5	b.l8x2	9.01333	Yes	No	0	4	4
360	b.l10x3	b.l6x5	5.23667	No	Yes	18	6	4
361	b.b7x1	b.b8x3	3.63	Yes	Yes	0	4	6
362	b.b7x1	b.b8x5	10.7267	Yes	No	0	4	4
363	b.b7x1	b.b9x1	3.95778	Yes	No	0	4	4
364	b.b7x1	b.l10x3	8.43	Yes	No	18	4	6
365	b.b7x2	b.l8x1	5.79444	No	Yes	8	8	5
366	b.b10x5	b.b7x3	3.23333	Yes	No	0	9	9
367	b.b7x4	b.b8x4	4.03444	No	Yes	8	8	6
368	b.l7x4	b.l9x5	3.95778	No	No	0	9	8
369	b.b9x3	b.l7x5	4.25	No	No	0	6	6
370	b.b8x1	b.l9x7	3.34778	No	No	0	8	7
371	b.b10x3	b.b8x1	3.43778	Yes	No	0	8	8
372	b.b8x2	b.b8x4	6.36	No	Yes	0	8	6
373	b.b8x2	b.b9x3	3.99222	No	No	0	8	6
374	b.b8x3	b.b9x4	4.12111	Yes	No	0	6	9
375	b.b10x5	b.b8x3	3.35	Yes	Yes	0	9	6
376	b.b8x3	b.l12x1	7.03333	Yes	No	0	6	6
377	b.b8x4	b.l8x8	2.94556	Yes	Yes	8	6	4
378	b.b8x4	b.l8x10	6.87	Yes	No	0	6	4
379	b.b8x5	b.l8x3	4.54778	No	Yes	0	4	3
380	b.l8x1	b.l8x8	3.14556	Yes	Yes	8	5	4
381	b.l8x3	b.l8x5	2.97778	Yes	Yes	25	3	3
382	b.l8x3	b.l8x9	3.30667	Yes	No	25	3	3
383	b.b12x6	b.b9x4	17.21	Yes	No	0	8	9
384	b.l9x3	b.l9x7	5.85667	Yes	No	10	9	7
385	b.b11x4	b.l9x3	7.15111	Yes	Yes	10	9	9
386	b.b11x6	b.l9x3	15.9633	No	Yes	10	9	9
387	b.l11x2	b.l9x3	4.76	Yes	Yes	10	9	9
388	b.b12x6	b.l9x3	6.58333	Yes	Yes	10	8	9
389	b.l11x2	b.l9x4	6.90556	Yes	No	0	9	5
390	b.l11x1	b.l9x6	5.63333	No	Yes	1	9	8
391	b.l13x6	b.l9x6	8.55667	Yes	Yes	1	9	8
392	b.b14x1	b.l9x6	4.65667	No	Yes	1	8	8
393	b.b11x4	b.l9x7	4.91444	Yes	No	10	9	7
394	b.b10x1	b.b11x5	4.16556	No	No	0	9	6
395	b.b10x2	b.b10x4	4.33222	No	No	0	6	6
396	b.b10x2	b.b14x3	3.52556	No	Yes	0	6	5
397	b.b10x3	b.b11x2	3.09111	Yes	Yes	0	8	7
398	b.b10x3	b.b11x4	3.38	Yes	Yes	0	8	9
399	b.b10x4	b.b14x5	3.64333	No	No	0	6	5
400	b.b10x5	b.b11x2	6.83667	Yes	Yes	0	9	7
401	b.b11x1	b.l10x1	7.24667	No	No	0	5	3
402	b.b14x5	b.l10x1	4.61333	No	No	0	5	3
403	b.b11x1	b.l10x2	5.65778	No	No	0	5	5
404	b.b12x7	b.l10x4	8.37667	No	No	0	9	3
405	b.l10x4	b.l12x2	8.18	No	No	0	3	6
406	b.b11x1	b.b12x5	3.69556	No	No	0	5	6
407	b.b11x2	b.b12x6	3.26	Yes	Yes	0	7	8
408	b.b11x2	b.l12x1	3.43667	Yes	No	0	7	6
409	b.b11x3	b.b14x3	4.30444	No	Yes	4	5	5
410	b.b11x4	b.b12x6	9.83889	Yes	Yes	10	9	8
411	b.b11x5	b.l13x7	5.02778	No	Yes	0	6	9
412	b.b11x5	b.b14x3	6.00778	No	Yes	0	6	5
413	b.b11x6	b.l11x2	7.35889	No	Yes	10	9	9
414	b.l11x1	b.l13x6	4.47111	No	Yes	1	9	9
415	b.b12x2	b.l11x2	8.35111	No	Yes	0	7	9
416	b.b12x2	b.l13x1	4.36111	No	No	0	7	2
417	b.b12x3	b.b13x7	3.72333	Yes	Yes	4	8	7
418	b.b12x3	b.l13x7	4.17333	Yes	Yes	4	8	9
419	b.b12x3	b.b15x1	3.10444	Yes	Yes	4	8	9
420	b.b12x3	b.b15x3	3.24889	Yes	Yes	4	8	9
421	b.b12x4	b.b12x6	3.74667	No	Yes	10	4	8
422	b.b12x4	b.b13x3	5.38889	No	No	10	4	4
423	b.b12x5	b.b13x4	3.60111	No	No	4	6	4
424	b.b12x5	b.b13x5	5.40444	No	No	4	6	4
425	b.b12x6	b.b13x3	13.0222	Yes	No	10	8	4
426	b.b12x7	b.l12x3	6.90667	No	No	0	9	5
427	b.b13x3	b.b13x6	5.19555	No	No	0	4	4
428	b.b13x4	b.b13x5	3.66333	No	No	4	4	4
429	b.b13x5	b.b13x7	6.05333	No	Yes	4	4	7
430	b.b13x7	b.b15x1	10.8356	Yes	Yes	4	7	9
431	b.b13x7	b.b16x6	14.3644	Yes	Yes	4	7	8
432	b.b13x7	b.b17x1	3.17778	Yes	No	0	7	4
433	b.l13x3	b.l13x7	6.61333	Yes	Yes	4	9	9
434	b.b15x3	b.l13x3	5.11333	Yes	Yes	4	9	9
435	b.b15x5	b.l13x3	7.96667	No	Yes	4	8	9
436	b.l13x3	b.l15x2	4.62	Yes	Yes	4	9	9
437	b.b16x4	b.l13x3	13.8278	Yes	Yes	4	6	9
438	b.b16x6	b.l13x3	3.76222	Yes	Yes	4	8	9
439	b.l13x4	b.l15x2	6.10222	No	Yes	0	3	9
440	b.b15x3	b.l13x7	2.87222	Yes	Yes	4	9	9
441	b.b14x1	b.l15x1	2.88	No	Yes	1	8	7
442	b.b14x2	b.b18x3	3.09444	No	Yes	0	7	8
443	b.b14x3	b.b15x1	6.09111	Yes	Yes	4	5	9
444	b.b14x4	b.b18x5	5.87333	No	No	0	8	5
445	b.b14x5	b.b15x1	3.11333	No	Yes	0	5	9
446	b.b18x5	b.l14x1	4.31444	No	No	0	5	4
447	b.l14x2	b.l18x4	3.15778	No	No	0	4	7
448	b.l14x3	b.l14x5	8.47	No	No	0	5	5
449	b.l14x5	b.l16x2	6.87222	No	No	0	5	9
450	b.b16x5	b.l14x6	5.22667	Yes	No	0	5	3
451	b.b15x1	b.b16x6	12.6956	Yes	Yes	4	9	8
452	b.b15x2	b.b16x5	2.98	Yes	Yes	0	6	5
453	b.b15x2	b.b18x3	4.60778	Yes	Yes	5	6	8
454	b.b15x2	b.b18x5	7.72111	Yes	No	0	6	5
455	b.b15x2	b.b19x2	10.3422	Yes	Yes	5	6	6
456	b.b15x3	b.b16x6	7	Yes	Yes	4	9	8
457	b.b15x4	b.l17x7	3.72444	No	No	0	6	7
458	b.b15x5	b.l15x2	3.09	No	Yes	4	8	9
459	b.l15x1	b.l17x6	8.99111	Yes	Yes	1	7	9
460	b.b16x2	b.l15x2	8.34333	No	Yes	0	5	9
461	b.b16x4	b.b16x6	8.24889	Yes	Yes	4	6	8
462	b.b16x4	b.b17x3	6.64556	Yes	No	4	6	5
463	b.b16x4	b.b17x6	12.3456	Yes	No	0	6	7
464	b.b16x5	b.b17x5	5.32333	Yes	Yes	0	5	7
465	b.b16x5	b.l20x1	6.15111	Yes	No	0	5	6
466	b.b16x6	b.b17x3	5.80444	Yes	No	4	8	5
467	b.b16x7	b.l16x3	10.3956	No	No	19	9	3
468	b.b16x7	b.b17x4	10.9844	No	No	19	9	5
469	b.b17x2	b.l16x3	9.32111	No	No	19	3	3
470	b.b17x4	b.l16x3	5.17	No	No	19	5	3
471	b.b17x2	g.h1x13	4.17111	No	No	0	3	1
472	b.b17x3	g.h1x10	4.91667	No	No	0	5	9
473	b.b17x5	b.b17x7	8.33	Yes	Yes	5	7	8
474	b.b17x5	b.b21x1	12.7622	Yes	Yes	5	7	7
475	b.b17x5	g.l1x2	4.11667	Yes	No	0	7	2
476	b.b17x6	g.h1x14	6.42889	No	No	0	7	9
477	b.b17x7	b.b19x2	10.3589	Yes	Yes	5	8	6
478	b.b17x7	b.b20x6	10.5989	Yes	Yes	5	8	6
479	b.b17x7	b.b21x1	4.64444	Yes	Yes	5	8	7
480	b.l17x3	b.l17x7	8.39667	Yes	No	5	9	7
481	b.b19x4	b.l17x3	8.97445	Yes	Yes	5	8	9
482	b.b19x6	b.l17x3	11.7778	No	Yes	5	9	9
483	b.l17x3	b.l19x2	3.92	Yes	Yes	5	9	9
484	b.b20x4	b.l17x3	14.9211	Yes	Yes	5	8	9
485	b.b20x6	b.l17x3	3.39667	Yes	Yes	5	6	9
486	b.l17x4	b.l19x2	7.65222	No	Yes	0	3	9
487	b.l17x5	b.l19x1	4.08889	No	No	0	6	9
488	b.l17x6	b.l19x1	7.68667	Yes	No	0	9	9
489	b.b19x4	b.l17x7	5.23556	Yes	No	5	8	7
490	b.b18x1	b.l19x1	10.77	No	No	0	9	9
491	b.b18x2	b.b22x3	3.01444	No	No	0	5	6
492	b.b18x3	b.b19x2	4.32333	Yes	Yes	5	8	6
493	b.b18x3	b.b19x4	4.39111	Yes	Yes	5	8	8
494	b.l18x1	b.l18x2	8.82667	Yes	Yes	15	6	7
495	b.b19x1	b.l18x1	3.08111	No	Yes	0	6	6
496	b.b22x5	b.l18x1	8.69444	Yes	Yes	15	7	6
497	b.l18x1	b.l22x4	4.85222	Yes	No	15	6	9
498	b.l18x1	g.h2x8	7.30778	Yes	No	0	6	7
499	b.l18x1	g.h2x11	4.58333	Yes	Yes	15	6	6
500	b.b22x5	b.l18x2	3.85111	Yes	Yes	15	7	7
501	b.l18x2	b.l22x4	3.83444	Yes	No	15	7	9
502	b.l18x2	g.h2x11	4.78778	Yes	Yes	15	7	6
503	b.l18x3	b.l18x5	9.23333	No	No	0	5	2
504	b.l18x3	g.h2x11	10.4656	No	Yes	0	5	6
505	b.l18x5	b.l20x2	9.37444	No	No	0	2	9
506	b.b19x2	b.b20x6	10.9578	Yes	Yes	5	6	6
507	b.b19x2	b.l20x1	2.84333	Yes	No	0	6	6
508	b.b19x3	b.b22x5	3.69667	No	Yes	0	4	7
509	b.b19x4	b.b20x6	6.77333	Yes	Yes	5	8	6
510	b.b19x5	b.l21x9	5.28889	No	No	0	5	6
511	b.b19x6	b.l19x2	7.19889	No	Yes	5	9	9
512	b.b20x2	b.l19x2	8.35222	No	Yes	0	6	9
513	b.b20x2	b.b20x4	7.90556	No	Yes	0	6	8
514	b.b20x2	b.l21x1	3.91111	No	No	0	6	2
515	b.b20x3	b.b21x7	3.73333	No	Yes	0	8	5
516	b.b20x3	b.l21x9	4.18444	No	No	0	8	6
517	b.b20x4	b.b20x6	4.03889	Yes	Yes	5	8	6
518	b.b20x4	b.b21x3	17.1878	Yes	No	5	8	6
519	b.b20x4	b.b21x6	8.76778	Yes	No	5	8	1
520	b.b20x5	b.b21x7	5.99111	No	Yes	0	7	5
521	b.b20x6	b.b21x3	6.21889	Yes	No	5	6	6
522	b.b20x7	b.l20x3	4.28667	No	No	0	9	7
523	b.b20x7	b.b21x4	11.46	No	No	0	9	5
524	b.b20x7	g.h2x4	3.60222	No	No	0	9	7
525	b.l20x2	g.l1x5	8.07333	No	No	0	9	4
526	b.l20x2	g.h2x7	9	No	No	0	9	5
527	b.b21x1	g.l1x4	12.7056	Yes	Yes	0	7	8
528	b.b21x2	g.h2x1	4.61778	No	No	0	6	8
529	b.b21x3	b.b21x6	3.76222	No	No	5	6	1
530	b.b21x5	b.b21x7	9.71222	Yes	Yes	0	4	5
531	b.b21x7	b.b23x2	5.6	Yes	No	0	5	6
532	b.b21x7	b.b24x6	9.54	Yes	Yes	0	5	8
533	b.l21x2	b.l21x4	8.50444	Yes	No	0	4	4
534	b.l21x2	b.l21x5	3.24	Yes	No	0	4	4
535	b.b25x3	b.l21x2	6.52222	Yes	Yes	0	5	4
536	b.b23x6	b.l21x5	6.44556	Yes	No	0	7	4
537	b.l21x7	b.l23x1	5.53444	No	Yes	0	5	6
538	b.l21x7	b.l23x2	7.60667	No	No	0	5	8
539	b.l21x8	b.l23x1	3.16556	No	Yes	0	4	6
540	b.b23x6	b.l21x9	9.80444	Yes	No	0	7	6
541	b.b22x1	b.b22x2	2.84444	No	No	0	8	8
542	b.b22x1	b.l23x1	2.89222	No	Yes	1	8	6
543	b.b22x1	b.l25x6	4.59889	No	Yes	1	8	8
544	b.b22x2	b.b26x3	6.17333	No	No	0	8	6
545	b.b22x4	b.b26x5	3.77222	No	No	0	5	7
546	b.b22x5	b.l22x4	2.84556	Yes	No	15	7	9
547	b.b22x5	b.b23x2	9.20444	Yes	No	0	7	6
548	b.b23x1	b.l22x1	3.66889	Yes	No	0	5	9
549	b.l22x1	g.ctx3	6.87	No	Yes	0	9	9
550	b.l22x1	g.ctx5	4.00222	No	No	0	9	9
551	b.l22x3	g.ctx3	9.32667	No	Yes	0	9	9
552	b.b24x7	b.l22x5	13.7611	No	Yes	14	9	9
553	b.l22x5	b.l24x2	8.90778	Yes	No	14	9	6
554	b.l22x5	g.h2x12	3.25222	Yes	No	14	9	7
555	b.l22x5	g.ctx6	4.72333	Yes	Yes	0	9	6
556	b.b23x1	b.b24x5	5.13222	Yes	No	0	5	5
557	b.b23x1	g.ctx6	3.38222	Yes	Yes	0	5	6
558	b.b23x3	b.b24x5	3.97333	No	No	0	7	5
559	b.b23x3	b.b27x1	5.79444	No	No	0	7	6
560	b.b23x4	b.b23x6	5.04222	No	Yes	0	6	7
561	b.b23x6	b.l23x2	3.83333	Yes	No	0	7	8
562	b.b23x6	b.b24x4	11.24	Yes	Yes	16	7	6
563	b.b23x6	b.b24x6	7.71667	Yes	Yes	16	7	8
564	b.l23x1	b.l25x6	18	Yes	Yes	1	6	8
565	b.b24x2	b.l23x2	6.13333	No	No	0	5	8
566	b.b24x1	b.l25x5	3.89111	No	No	0	4	7
567	b.b24x2	b.b25x6	5.25333	No	No	0	5	3
568	b.b24x2	b.l25x1	3.12556	No	No	0	5	3
569	b.b24x3	b.b25x7	5.29111	No	No	0	5	7
570	b.b24x4	b.b24x6	4.01778	Yes	Yes	16	6	8
571	b.b24x4	b.b25x3	10.58	Yes	Yes	16	6	5
572	b.b24x4	b.b25x6	2.95667	Yes	No	16	6	3
573	b.b24x6	b.b25x3	5.33222	Yes	Yes	16	8	5
574	b.b24x7	b.l24x3	6.29889	No	Yes	0	9	5
575	b.l24x2	g.h2x12	5.64444	No	No	14	6	7
576	b.b25x2	b.l24x3	3.84111	No	Yes	0	2	5
577	b.b25x3	b.b25x6	3.19778	Yes	No	16	5	3
578	b.b25x7	b.b28x6	14.9333	No	Yes	0	7	9
579	b.l25x3	b.l25x7	5.23	Yes	No	0	9	7
580	b.b27x3	b.l25x3	7.75778	No	Yes	0	8	9
581	b.b27x5	b.l25x3	14.4122	No	Yes	13	9	9
582	b.l25x3	b.l28x2	6.72111	Yes	Yes	13	9	9
583	b.b28x4	b.l25x3	11.0622	Yes	Yes	13	6	9
584	b.l25x4	b.l28x2	3.69444	No	Yes	0	5	9
585	I1x48	b.l25x4	10.6567	No	No	0	5	5
586	b.l25x5	b.l28x1	7.40778	No	Yes	0	7	9
587	b.l25x6	b.l28x1	22.4344	Yes	Yes	1	8	9
588	b.b26x1	b.l28x1	5.76444	No	Yes	0	9	9
589	b.b26x3	b.b27x3	4.75	No	No	0	6	8
590	b.b26x5	b.b27x1	4.63222	No	No	0	7	6
591	b.l27x1	b.l27x3	7.71	No	No	6	7	7
592	b.l27x3	b.l27x5	7.08556	No	No	0	7	5
593	b.l27x5	g.ctx4	6.89556	No	No	0	5	7
594	b.l27x5	g.ctx15	5.40444	No	Yes	0	5	9
595	b.l27x6	g.ctx16	4.46778	No	Yes	0	7	8
596	b.b27x3	b.b28x6	9.29889	No	Yes	0	8	9
597	b.b27x5	b.l28x2	8.34	No	Yes	13	9	9
598	b.b28x2	b.l28x2	8.62667	No	Yes	0	4	9
599	b.b28x4	b.b28x6	7.21778	Yes	Yes	13	6	9
600	b.b28x5	g.ctx16	4.46556	No	Yes	9	5	8
601	b.b28x7	g.ctx14	11.2011	Yes	Yes	9	9	9
602	b.b28x7	g.ctx16	3.89222	Yes	Yes	9	9	8
603	g.l1x2	g.l1x4	4.73222	No	Yes	0	2	8
604	g.h2x3	g.l1x5	4.84778	No	No	0	5	4
605	g.h2x11	g.h2x15	16.3322	Yes	No	0	6	6
606	g.ctx2	g.h2x15	4.10333	No	No	0	3	6
607	g.ctx3	g.ctx4	3.75667	Yes	No	0	9	7
608	g.ctx3	g.ctx6	9.80111	Yes	Yes	0	9	6
609	g.ctx10	g.ctx9	2.94333	No	No	26	5	6
610	g.ctx13	g.ctx9	2.85333	No	No	26	5	6
611	g.ctx10	g.ctx13	6.11333	No	No	26	5	5
612	g.ctx14	g.ctx15	5.79556	Yes	Yes	9	9	9
613	g.ctx14	g.ctx16	3.89333	Yes	Yes	9	9	8
614	g.ctx15	g.ctx16	4.17222	Yes	Yes	9	9	8
615	NT	NT	9.64444	Yes	Yes	2	5	5
616	2x64	NT	8.49778	Yes	Yes	2	3	5
617	E2	NT	16.1033	Yes	Yes	2	5	5
618	2x65	NT	5.32222	Yes	Yes	2	4	5
619	7x31	NT	6.93111	No	Yes	2	2	5
620	7x32	NT	4.80556	No	Yes	2	2	5
621	1x28	1x29	3.90222	No	No	0	7	4
622	1x31	7x36	7.54889	No	No	0	5	4
623	1x35	7x36	4.25778	No	No	0	5	4
624	1x38	1x42	2.92	No	Yes	0	5	6
625	1x38	7x39	3.14111	No	No	0	5	5
626	1x39	7x39	3.56222	No	No	0	6	5
627	1x42	7x42	2.92111	Yes	No	0	6	6
628	1x42	7x47	3.79556	Yes	Yes	0	6	6
629	1x45	7x47	3.41556	No	Yes	0	4	6
630	1x46	2x54	5.39889	No	No	0	7	8
631	1x46	7x47	5.86667	No	Yes	0	7	6
632	1x47	2x51	3.49111	No	Yes	0	6	7
633	1x49	7x47	3.51444	No	Yes	0	8	6
634	1x49	7x50	5.41333	No	No	0	8	9
635	1x50	2x50	8.67778	Yes	Yes	0	9	9
636	1x50	2x51	3.24	Yes	Yes	0	9	7
637	1x50	7x50	4.89	Yes	No	0	9	9
638	1x51	2x51	3.36667	No	Yes	0	5	7
639	1x55	1x59	8.14444	No	No	0	5	5
640	1x60	I1x50	7.34222	No	No	0	7	8
641	2x40	I1x50	7.03333	Yes	No	7	8	8
642	8x49	I1x50	3.55	Yes	No	7	6	8
643	4x39	I1x51	3.08	No	No	0	3	3
644	2x37	2x40	7.66889	No	Yes	7	6	8
645	2x37	8x49	7.08444	No	Yes	7	6	6
646	2x38	I2x57	3.71667	No	No	0	5	6
647	2x39	3x49	5.4	No	Yes	0	8	9
648	2x40	8x47	7.06556	Yes	No	7	8	8
649	2x40	8x49	7.64333	Yes	Yes	7	8	6
650	2x40	8x50	4.92444	Yes	No	7	8	8
651	2x42	3x45	10.0144	No	No	0	8	6
652	2x42	3x49	3.98111	No	Yes	0	8	9
653	2x45	3x42	4.34667	No	No	0	9	8
654	2x45	4x46	8.06111	No	No	27	9	8
655	2x45	4x50	4.94444	No	Yes	27	9	9
656	2x46	3x42	6.00778	Yes	No	0	9	8
657	2x46	3x43	4.76889	Yes	No	11	9	8
658	2x46	7x49	3.51	Yes	No	0	9	9
659	2x46	7x53	2.99556	Yes	Yes	11	9	9
660	2x50	7x46	8.83444	Yes	No	0	9	9
661	2x50	7x49	3.88889	Yes	No	0	9	9
662	2x52	3x35	3.12333	No	No	0	7	7
663	2x53	3x35	3.66222	No	No	0	8	7
664	2x57	2x61	7.14333	Yes	No	2	6	6
665	2x57	3x32	4.51444	Yes	No	2	6	5
666	2x57	3x36	3.93	Yes	Yes	2	6	6
667	2x57	7x38	3.96222	Yes	No	2	6	5
668	2x57	7x42	4.19556	Yes	No	0	6	6
669	2x57	Lig	9.15889	Yes	Yes	2	6	0
670	2x60	3x28	6.46	No	No	0	4	5
671	2x60	Lig	3.98667	No	Yes	0	4	0
672	2x61	2x65	11.0622	No	Yes	2	6	4
673	2x61	Lig	3.70111	No	Yes	2	6	0
674	2x63	E1	5.61556	No	Yes	0	3	4
675	2x64	2x65	8.42	Yes	Yes	2	3	4
676	2x64	E1	3.47222	Yes	Yes	2	3	4
677	2x64	Lig	10.8567	Yes	Yes	2	3	0
678	2x65	Lig	3.50333	Yes	Yes	2	4	0
679	2x66	E1	3.05889	No	Yes	0	4	4
680	3x25	E1	3.58667	Yes	Yes	2	9	4
681	3x28	E1	3.09111	No	Yes	0	5	4
682	3x21	3x24	4.13111	No	No	0	6	4
683	3x22	E2	10.36	No	Yes	0	3	5
684	3x25	3x29	5.40444	Yes	No	2	9	4
685	3x25	E2	10.2367	Yes	Yes	2	9	5
686	3x26	4x60	3.28444	No	No	0	5	5
687	3x26	4x61	5.22667	No	No	0	5	6
688	3x26	E2	4.00556	No	Yes	2	5	5
689	3x29	E2	5.19333	No	Yes	2	4	5
690	3x29	Lig	5.59111	No	Yes	2	4	0
691	3x32	Lig	4.00222	No	Yes	2	5	0
692	3x33	4x57	3.74889	Yes	No	0	4	7
693	3x33	Lig	10.3056	Yes	Yes	2	4	0
694	3x34	4x57	4.00333	No	No	0	5	7
695	3x34	4x58	6.25333	No	No	0	5	4
696	3x36	6x48	5.23444	Yes	Yes	2	6	8
697	3x36	7x41	6.51778	Yes	No	2	6	7
698	3x36	Lig	4.24667	Yes	Yes	2	6	0
699	3x37	4x53	3.23556	No	No	0	6	8
700	3x37	5x43	5.65889	No	Yes	0	6	5
701	3x38	4x50	7.77889	No	Yes	0	7	9
702	3x40	5x50	3.47667	No	Yes	0	8	7
703	3x40	5x51	4.28222	No	Yes	0	8	7
704	3x41	4x49	4.26889	No	No	0	5	6
705	3x43	7x53	6.51333	No	Yes	11	8	9
706	3x44	3x48	4.73222	Yes	No	0	6	6
707	3x44	5x50	3.87444	Yes	Yes	0	6	7
708	3x44	5x53	3.57	Yes	No	0	6	5
709	3x44	5x54	3.39333	Yes	No	0	6	8
710	3x45	4x49	4.23889	No	No	0	6	6
711	3x46	7x53	3.74556	No	Yes	11	9	9
712	3x47	5x58	5.18889	No	Yes	0	9	9
713	3x49	I2x53	9.45111	Yes	Yes	0	9	7
714	3x49	I2x57	4.71	Yes	No	0	9	6
715	3x50	5x58	6.4	Yes	Yes	11	9	9
716	3x50	7x53	7.65889	Yes	Yes	11	9	9
717	3x51	3x55	12.3656	No	Yes	20	8	6
718	3x51	5x57	3.10889	No	No	0	8	6
719	3x51	5x60	9.71444	No	Yes	20	8	5
720	3x53	I2x53	8.34333	No	Yes	0	8	7
721	3x54	5x61	3.29889	No	No	0	9	9
722	3x54	5x64	3.19222	No	Yes	0	9	6
723	3x55	3x56	16.1	Yes	No	0	6	5
724	3x55	5x64	3.72	Yes	Yes	20	6	6
725	I2x50	I2x51	5.52444	No	No	0	8	7
726	I2x53	I2x54	3.45	Yes	No	7	7	5
727	4x38	4x41	4.49556	No	No	0	9	6
728	4x46	4x50	4.59556	No	Yes	27	8	9
729	4x56	5x46	5.44	No	No	0	5	5
730	4x59	E2	4.05	No	Yes	0	5	5
731	4x60	5x39	10.3522	No	Yes	0	5	7
732	5x36	E2	17.0322	No	Yes	2	4	5
733	5x38	E2	6.16778	No	Yes	2	4	5
734	5x39	E2	7.75222	Yes	Yes	2	7	5
735	E2	E2	43.6533	Yes	Yes	2	5	5
736	5x37	E2	6.25333	No	Yes	2	4	5
737	5x40	E2	6.32556	No	Yes	0	5	5
738	E2	E3	12.0489	Yes	Yes	2	5	1
739	7x31	E2	4.25778	No	Yes	2	2	5
740	6x58	E2	10.0333	No	Yes	0	3	5
741	7x34	E2	12.0878	Yes	Yes	2	4	5
742	6x55	E2	3.51222	No	Yes	2	6	5
743	E2	Lig	29.9044	Yes	Yes	2	5	0
744	5x39	5x43	4.07111	Yes	Yes	2	7	5
745	5x39	Lig	3.30556	Yes	Yes	2	7	0
746	5x41	6x59	4.39778	No	No	0	4	3
747	5x43	5x47	10.9389	Yes	No	0	5	7
748	5x43	6x55	3.87667	Yes	No	2	5	6
749	5x43	Lig	11.1033	Yes	Yes	2	5	0
750	5x44	6x55	5.39778	No	No	0	4	6
751	5x46	5x50	3.98556	No	Yes	0	5	7
752	5x47	5x51	4.38444	No	Yes	0	7	7
753	5x51	6x44	3.76333	Yes	No	0	7	9
754	5x51	6x48	6.61111	Yes	Yes	0	7	8
755	5x55	6x41	3.54333	No	No	0	5	7
756	5x56	5x60	7.35222	No	Yes	0	4	5
757	5x58	6x37	8.85889	Yes	No	0	9	8
758	5x58	6x40	4.53333	Yes	No	11	9	8
759	5x58	6x41	6.38222	Yes	No	0	9	7
760	5x58	7x53	3.52889	Yes	Yes	11	9	9
761	5x60	5x64	5.17111	Yes	Yes	20	5	6
762	5x62	6x37	3.69	No	No	0	6	8
763	5x63	5x67	3.89556	No	No	0	3	5
764	5x66	6x30	7.70111	No	Yes	0	5	7
765	5x69	6x29	3.02	No	No	0	5	5
766	5x69	6x30	7.39556	No	Yes	0	5	7
767	6x28	6x32	5.66556	No	No	0	4	8
768	6x36	7x56	11.0667	No	No	0	8	7
769	6x39	7x56	3.77889	No	No	0	6	7
770	6x40	7x52	2.84556	No	Yes	0	8	9
771	6x40	7x53	6.65889	No	Yes	11	8	9
772	6x43	7x52	3.58556	No	Yes	0	7	9
773	6x47	7x45	8.22222	No	No	0	8	9
774	6x48	7x41	6.38667	Yes	No	2	8	7
775	6x48	7x45	5.39889	Yes	No	0	8	9
776	6x49	6x50	3.43778	No	No	0	5	9
777	6x54	7x34	6.30556	No	Yes	0	4	4
778	7x29	7x32	7.39556	No	No	0	3	2
779	7x34	Lig	5.52	Yes	Yes	2	4	0
780	7x38	Lig	6.08556	No	Yes	2	5	0
781	7x45	7x49	9.83889	No	No	0	9	9
782	7x48	7x52	3.41444	No	Yes	0	6	9
783	7x51	7x55	2.92333	No	No	0	6	6
784	8x47	8x50	4.61556	No	No	7	8	8
785	8x48	8x51	4.16111	No	No	0	4	8
786	G.HN.52	I2x55	3.08778	No	No	0	4	4
787	G.hns1.03	I2x52	3.81444	No	No	0	4	5
788	G.S1.03	G.S3.04	3.03333	No	Yes	1	9	6
789	G.S1.04	G.S3.03	2.97667	No	Yes	0	7	7
790	G.S1.07	G.S4.02	3.01333	No	Yes	1	9	8
791	G.H3.01	G.s1h1.04	5.81556	Yes	No	0	9	9
792	G.H1.01	G.S3.07	7.68222	Yes	No	3	9	9
793	G.S2.03	G.S3.04	6	No	Yes	1	9	6
794	G.H2.03	b.l15x1	3.54667	Yes	Yes	1	9	7
795	G.H2.04	G.H3.08	3.50778	Yes	No	0	9	9
796	G.HG.17	G.s4h3.05	3.57778	No	Yes	0	3	9
797	G.H3.01	G.s4h3.06	5.26333	Yes	No	23	9	8
798	G.H4.02	G.H4.04	4.07556	No	No	0	5	4
799	G.H5.17	G.h4s6.12	3.9	No	No	0	5	4
800	G.H5.05	G.H5.09	3.77222	No	Yes	3	5	4
801	b.1x13	b.1x16	5.35778	No	Yes	0	1	4
802	b.lhb1x10	b.lhb1x8	3.63444	No	No	0	4	2
803	b.l7x3	b.l7x5	3.88889	No	No	0	9	6
804	b.b8x1	b.b9x4	4.05556	No	No	0	8	9
805	b.l8x5	b.l8x7	3.50556	Yes	No	0	3	3
806	b.l8x5	b.l8x9	3.36	Yes	No	25	3	3
807	b.b11x3	b.b15x1	3.20222	No	Yes	4	5	9
808	b.b16x7	b.l14x6	3.77	No	No	0	9	3
809	b.b17x2	b.b17x4	3.03222	No	No	19	3	5
810	b.l17x5	b.l19x2	3.76333	No	Yes	0	6	9
811	b.b20x5	b.b21x4	3.23	No	No	0	7	5
812	g.h1x10	g.h1x14	5.94556	No	No	0	9	9
813	g.h2x3	g.h2x7	4.30111	No	No	0	5	5
814	E1	NT	10.2322	Yes	Yes	2	4	5
815	1x31	NT	4.28889	No	Yes	2	5	5
816	1x54	2x48	3.24889	No	No	0	7	7
817	2x64	3x25	3.09556	Yes	Yes	2	3	9
818	3x24	E1	3.42	No	Yes	0	4	4
819	3x33	5x43	4.31111	Yes	Yes	2	4	5
820	I3	I3	4.37444	Yes	Yes	3	3	3
821	7x30	E3	6.20667	No	Yes	0	3	1
822	8x60	8x61	3.05667	No	No	0	5	3
823	G.S4.07	G.s5hg.01	2.85444	No	No	0	8	9
824	G.h4s6.09	G.h4s6.10	3.53444	No	No	0	3	3
825	G.H5.22	I2x53	3.32111	No	Yes	7	4	7
826	b.1x13	b.1x9	3.21333	No	No	0	1	4
827	b.b1x1	b.lhb1x10	3.11444	No	No	0	5	4
828	3x46	3x50	3.44889	No	Yes	11	9	9
829	5x36	5x38	2.96444	No	No	2	4	4
830	6x39	7x52	3.96556	No	Yes	0	6	9
831	6x57	E3	3.58111	No	Yes	0	4	1
832	G.hgh4.03	G.hgh4.04	4.71667	No	No	0	5	6
833	b.1x16	b.1x17	3.04222	Yes	No	0	4	2
834	1x59	8x57	3.54778	No	No	0	5	6
835	1x28	1x31	5.91	No	No	0	7	5
836	G.H2.01	G.H2.07	3.44333	No	Yes	0	9	9
837	3x55	5x60	2.90333	Yes	Yes	20	6	5
838	6x51	7x34	2.84	No	Yes	0	6	4
839	G.H1.03	G.H1.07	2.83444	No	No	0	9	9
840	b.1x10	b.1x7	2.83222	No	No	0	1	8
841	3x30	3x33	2.83111	No	Yes	0	6	4
842	1x53	7x54	2.82889	No	No	0	9	8
843	1x57	2x40	2.82111	No	Yes	0	8	8
844	b.b10x2	b.b6x2	2.81667	No	No	0	6	8
845	3x45	4x45	2.80667	No	No	0	6	6
846	b.h2x1	g.h2x5	2.80444	Yes	No	0	5	6
847	G.H5.14	G.H5.18	2.79333	No	No	0	7	4
848	3x27	4x61	2.79222	No	No	0	4	6
849	2x51	2x55	2.78667	Yes	No	0	7	4
850	6x48	6x52	2.78444	Yes	No	0	8	6
851	g.h1x1	g.h1x5	2.78333	No	No	0	2	6
852	5x64	5x67	2.77111	Yes	No	0	6	5
853	G.S2.02	G.S3.07	2.75778	No	No	0	5	9
854	G.HN.42	G.HN.45	2.75556	No	No	0	4	4
855	b.l14x1	b.l14x3	2.74556	No	No	0	4	5
856	2x49	4x50	2.73444	No	Yes	0	8	9
857	G.h4s6.04	G.h4s6.10	2.73222	No	No	0	4	3
858	I1	I1x49	2.72667	No	No	0	7	6
859	G.H4.01	G.HG.14	2.71556	No	No	0	3	5
860	b.b5x3	b.l1x2	2.71333	Yes	No	0	9	9
861	b.l22x2	b.l27x4	2.71222	No	No	0	1	9
862	G.S4.01	G.S5.03	2.70778	No	Yes	0	8	8
863	1x29	1x30	2.70667	No	No	0	4	4
864	b.lhb1x4	b.lhb1x5	2.68333	No	No	0	1	1
865	8x47	G.H5.24	2.68222	No	No	0	8	8
866	b.b13x2	b.l12x3	2.67556	No	No	0	4	5
867	b.h2x2	b.lh12x4	2.66667	No	No	0	1	3
868	b.b27x4	b.b28x3	2.66	No	Yes	0	5	7
869	b.b26x4	b.b2x5	2.65444	No	Yes	0	5	7
870	b.b22x3	b.b23x2	2.64889	No	No	0	6	6
871	1x36	2x66	2.63889	No	No	0	5	4
872	1x49	7x51	2.63444	No	No	0	8	6
873	2x53	3x36	2.61889	No	Yes	0	8	6
874	b.l24x3	b.lhb1x5	2.60222	Yes	No	0	5	1
875	G.H3.02	G.H4.11	2.59333	No	No	0	8	7
876	b.lhb1x3	g.h2x9	2.59333	No	No	0	2	4
877	G.HG.13	G.HG.14	2.57111	No	No	0	7	5
878	1x60	8x53	2.57111	No	No	0	7	7
879	1x56	8x53	2.56778	No	No	0	8	7
880	g.ctx12	g.ctx13	2.55444	No	No	0	6	5
881	G.HG.06	G.HG.07	2.55	No	No	0	5	9
882	4x38	4x40	2.54889	No	No	0	9	4
883	2x56	3x31	2.54667	No	No	0	4	4
884	3x31	4x58	2.54556	No	No	0	4	4
885	b.1x15	g.h1x15	2.52667	No	No	0	7	8
886	b.b6x1	b.l7x1	2.52222	No	No	0	9	9
887	b.1x11	b.1x7	2.50444	No	No	0	8	8
888	G.H4.10	G.hgh4.04	2.49333	Yes	No	0	6	6
889	G.H1.09	G.S2.06	2.48	No	Yes	0	7	9
890	1x56	8x54	2.47889	No	No	0	8	6
891	2x62	2x66	2.47778	No	No	0	5	4
892	b.b15x1	b.l16x1	2.47444	Yes	No	0	9	4
893	1x32	E1	2.47444	No	Yes	0	5	4
894	2x42	4x42	2.46333	No	No	0	8	7
895	2x41	4x43	2.46	No	No	0	4	1
896	G.HN.50	G.HN.53	2.45889	No	No	0	5	1
897	b.l10x1	b.l14x4	2.45667	No	No	0	3	1
898	1x54	2x47	2.45333	No	No	0	7	9
899	H.HC.11	H.HD.04	2.43333	No	No	0	8	6
900	1x56	8x57	2.43111	No	No	0	8	6
901	b.b12x7	b.b13x4	2.41222	No	No	0	9	4
902	b.b2x2	b.b6x3	2.41	No	No	0	7	8
903	b.l22x2	g.ctx2	2.4	No	No	0	1	3
904	2x59	2x63	2.39222	No	No	0	7	3
905	1x42	7x43	2.37333	Yes	No	0	6	4
906	b.b9x2	b.l12x1	2.36889	No	No	0	5	6
907	g.ctx4	g.ctx9	2.35444	No	No	0	7	6
908	b.b25x5	b.lhb1x8	2.33333	No	No	0	4	2
909	g.ctx7	g.ctx8	2.33333	No	No	0	4	8
910	7x54	8x50	2.31778	No	No	0	8	8
911	b.1x2	b.ntx3	2.31	No	No	0	1	5
912	b.b16x3	b.b19x2	2.30889	No	Yes	0	6	6
913	g.h1x11	g.h1x7	2.30778	No	No	0	9	2
914	g.ctx11	g.ctx17	2.30667	No	No	0	4	7
915	5x37	6x59	2.28889	No	No	0	4	3
916	5x62	6x34	2.27889	No	No	0	6	8
917	g.h2x14	g.h2x15	2.27778	No	No	0	4	6
918	G.H3.04	G.H3.07	2.25	No	No	0	9	5
919	b.1x12	b.1x9	2.25	No	No	0	6	4
920	b.b23x5	b.l25x7	2.24889	No	No	0	7	7
921	G.s6h5.02	G.s6h5.05	2.24667	Yes	Yes	0	7	9
922	b.b10x5	b.l6x2	2.24556	Yes	No	0	9	6
923	b.lh12x2	b.lh12x3	2.22889	No	No	0	8	4
924	b.l8x4	b.l8x5	2.19667	No	Yes	0	3	3
925	b.1x5	b.1x9	2.19667	No	No	0	3	4
926	b.h2x3	b.lh12x3	2.19333	No	No	0	1	4
927	6x31	6x35	2.19222	No	No	0	5	7
928	b.1x14	g.h1x15	2.19111	No	No	0	4	8
929	G.H5.01	G.H5.02	2.16778	No	No	0	9	4
930	b.1x22	g.l1x4	2.16778	No	Yes	0	3	8
931	G.HN.43	b.b5x6	2.16222	Yes	No	0	9	6
932	b.b22x5	b.l24x1	2.15667	Yes	No	0	7	5
933	b.b10x5	b.b6x4	2.15444	Yes	No	0	9	7
934	G.S1.05	G.h2s4.04	2.15222	Yes	No	0	9	9
935	4x63	E2	2.14	No	Yes	0	4	5
936	6x57	6x61	2.13111	No	No	0	4	3
937	b.1x3	b.ntx1	2.12444	No	No	0	1	0
938	b.b7x5	b.l7x1	2.11	No	No	0	9	9
939	3x52	I2x53	2.10667	No	Yes	0	5	7
940	2x41	4x42	2.09	No	No	0	4	7
941	I1x48	I1x51	2.08333	No	No	0	5	3
942	3x56	I2x56	2.08333	No	No	0	5	4
943	b.b1x4	g.ctx18	2.06889	Yes	No	0	7	6
944	G.HN.45	G.HN.49	2.06667	No	No	0	4	4
945	1x43	1x46	2.04444	No	No	0	7	7
946	b.b28x1	b.l1x3	2.01333	No	Yes	0	4	9
947	3x56	I2x52	2.01333	No	No	0	5	5
948	G.S2.04	G.S3.05	2.01	No	Yes	0	6	7
949	G.H4.06	G.HG.04	2.00111	No	Yes	0	7	9
950	b.b13x1	b.b9x2	2	No	No	0	4	5
951	G.H5.02	G.s6h5.05	1.99778	No	Yes	0	4	9
952	b.l7x5	b.l9x1	1.98444	No	No	0	6	5
953	8x49	G.H5.21	1.97889	Yes	No	0	6	5
954	3x34	4x54	1.97333	No	No	0	5	3
955	6x54	7x37	1.96667	No	No	0	4	4
956	b.l1x4	b.l3x2	1.96222	No	Yes	0	6	9
957	2x50	3x39	1.96222	Yes	No	0	9	9
958	b.b16x2	b.l17x1	1.95556	No	No	0	5	2
959	2x44	2x47	1.95	No	No	0	7	9
960	G.HN.09	G.HN.11	1.94	No	Yes	0	5	2
961	6x47	7x40	1.94	No	No	0	8	8
962	G.H1.01	G.s3h2.01	1.93556	Yes	No	0	9	9
963	4x39	I1	1.92111	No	No	0	3	7
964	3x21	3x23	1.91889	No	No	0	6	1
965	1x50	2x47	1.90889	Yes	No	0	9	9
966	b.1x1	g.h1x1	1.90111	Yes	No	0	4	2
967	G.HN.51	b.l1x4	1.9	No	No	0	5	6
968	G.H3.05	G.s1h1.02	1.9	No	No	0	9	7
969	G.S4.07	G.s1h1.05	1.9	No	No	0	8	9
970	6x30	6x31	1.89333	Yes	No	0	7	5
971	2x40	2x43	1.88222	Yes	No	0	8	8
972	G.s3h2.01	G.s3h2.02	1.87556	No	No	0	9	9
973	b.b28x6	b.l25x2	1.87556	Yes	No	0	9	5
974	b.l14x1	b.l14x2	1.87	No	No	0	4	4
975	b.b4x1	b.l5x4	1.85778	No	No	0	8	8
976	5x75	G.H5.09	1.85333	No	Yes	0	0	4
977	6x49	6x53	1.84778	No	No	0	5	5
978	6x50	7x40	1.82222	No	No	0	9	8
979	G.hfs2.06	G.hfs2.07	1.82	No	No	0	7	9
980	b.b12x1	b.l13x5	1.82	No	No	0	6	5
981	G.HN.48	G.HN.52	1.80778	No	No	0	3	4
982	b.h2x4	g.h2x5	1.80222	No	No	0	3	6
983	g.ctx1	g.ctx2	1.8	No	No	0	1	3
984	G.HG.05	G.HG.09	1.8	No	No	0	5	2
985	7x28	7x30	1.78556	No	No	0	3	3
986	G.H1.05	G.S2.04	1.76333	No	No	0	6	6
987	G.H3.01	G.H3.04	1.75333	Yes	No	0	9	9
988	b.l2x2	b.l6x2	1.75	No	No	0	1	6
989	8x48	8x49	1.74667	No	Yes	0	4	6
990	5x44	6x56	1.73111	No	No	0	4	5
991	4x61	4x62	1.72667	No	No	0	6	4
992	b.b18x4	b.b22x4	1.72	No	No	0	3	5
993	5x66	5x70	1.69111	No	No	0	5	5
994	H.HA.17	b.b9x2	1.68778	No	No	0	5	5
995	4x39	4x40	1.64667	No	No	0	3	4
996	b.b20x1	b.l21x5	1.62222	No	No	0	5	4
997	b.l13x1	b.l13x2	1.61778	No	No	0	2	6
998	b.b21x5	b.b25x1	1.61	Yes	No	0	4	2
999	6x59	6x60	1.60222	No	No	0	3	4
1000	H.HE.08	H.HE.11	1.58778	No	No	0	5	8
1001	G.s4h3.11	G.s4h3.12	1.58778	No	No	0	0	0
1002	5x65	6x33	1.58	No	No	0	8	7
1003	b.b12x6	b.l9x2	1.56444	Yes	No	0	8	5
1004	G.H4.13	G.H4.17	1.55667	No	No	0	3	4
1005	b.1x8	g.h1x8	1.51	No	No	0	5	7
1006	5x39	5x42	1.50889	Yes	No	0	7	5
1007	g.h1x3	g.h1x6	1.50667	No	No	0	3	4
1008	1x55	8x61	1.5	No	No	0	5	3
1009	7x27	E3	1.48778	No	Yes	0	2	1
1010	H.HE.04	H.HF.06	1.48667	No	Yes	0	9	6
1011	g.ctx6	g.ctx7	1.47222	Yes	No	0	6	4
1012	b.b16x1	b.l17x3	1.46	No	Yes	0	4	9
1013	G.HN.46	G.HN.49	1.45778	No	No	0	4	4
1014	G.HG.02	G.s6h5.04	1.44667	No	No	0	9	8
1015	b.lhb1x6	b.lhb1x7	1.43111	No	No	0	3	1
1016	b.1x5	g.h1x3	1.42778	No	No	0	3	3
1017	b.l17x1	b.l17x2	1.41556	No	No	0	2	6
1018	G.s4h3.08	G.s4h3.14	1.41333	No	Yes	0	0	6
1019	8x58	8x62	1.41	No	No	0	6	4
1020	1x37	1x41	1.37889	No	No	0	5	4
1021	H.HA.23	H.HB.08	1.37222	No	No	0	4	1
1022	b.lhb1x1	b.lhb1x2	1.36222	No	No	0	1	1
1023	g.h1x6	g.h1x9	1.35	No	No	0	4	6
1024	G.H3.14	G.h4s6.04	1.34222	Yes	No	0	8	4
1025	4x52	4x56	1.31556	Yes	No	0	4	5
1026	8x60	8x63	1.31	No	No	0	5	2
1027	G.HN.45	G.HN.48	1.30444	No	No	0	4	3
1028	G.H1.02	G.s1h1.04	1.27778	No	No	0	9	9
1029	4x48	4x52	1.26889	No	Yes	0	3	4
1030	b.l21x2	b.l21x3	1.26	Yes	No	0	4	3
1031	5x41	5x45	1.23	No	No	0	4	3
1032	G.H3.03	G.s4h3.13	1.23	No	No	0	4	0
1033	H.HC.08	H.HE.10	1.22889	No	No	0	3	3
1034	b.b12x1	b.l13x3	1.21778	No	Yes	0	6	9
1035	1x58	I1x51	1.21333	No	No	0	4	3
1036	G.H3.04	G.s4h3.14	1.20333	No	Yes	0	9	6
1037	H.HA.12	H.hbhc.14	1.19778	No	No	0	4	3
1038	G.s6h5.02	G.s6h5.03	1.19667	Yes	No	0	7	9
1039	H.HD.07	H.HD.11	1.18778	Yes	No	0	5	6
1040	b.1x16	b.1x19	1.18444	Yes	Yes	0	4	6
1041	G.s4h3.08	G.s4h3.10	1.17889	No	No	0	0	0
1042	G.S2.02	G.hfs2.02	1.16222	No	No	0	5	0
1043	2x65	7x35	1.13889	Yes	No	0	4	4
1044	H.HA.11	H.HF.03	1.13556	No	No	0	8	9
1045	g.h1x3	g.ntx1	1.13111	No	No	0	3	0
1046	8x52	8x55	1.12889	No	No	0	4	4
1047	H.HA.03	H.HA.07	1.12222	No	No	0	8	5
1048	b.b1x4	g.ctx19	1.1	Yes	No	0	7	0
1049	G.s4h3.11	G.s4h3.14	1.07889	No	Yes	0	0	6
1050	g.ctx14	g.ctx17	1.07222	Yes	No	0	9	7
1051	1x43	2x58	1.07111	No	No	0	7	6
1052	H.HA.24	H.HA.28	1.06667	No	No	0	3	3
1053	b.lhb1x3	g.h2x13	1.06333	No	No	0	2	1
1054	H.HB.04	H.HC.10	1.05556	No	No	0	1	7
1055	g.h1x15	g.l1x1	1.04	No	No	0	8	1
1056	H.hbhc.04	b.l8x9	1.03333	No	No	0	3	3
1057	H.HF.03	H.hehf.04	1.02222	No	No	0	9	8
1058	G.H1.11	G.S2.07	1.01333	No	No	0	0	3
1059	b.1x1	g.ntx8	1	Yes	No	0	4	4
1060	G.HN.11	G.HN.37	0.993333	Yes	No	0	2	3
1061	H.HA.19	H.HC.07	0.981111	Yes	Yes	21	6	6
1062	5x55	6x45	0.964444	No	No	0	5	6
1063	1x41	1x42	0.952222	No	Yes	0	4	6
1064	H.HE.04	H.HE.08	0.894444	No	No	0	9	5
1065	H.HA.17	H.hdhe.04	0.88	No	No	0	5	6
1066	H.HB.07	H.HC.06	0.872222	No	No	0	2	5
1067	G.s1h1.02	G.s1h1.03	0.866667	No	No	0	7	8
1068	b.1x10	b.1x6	0.853333	No	No	0	1	3
1069	5x49	5x50	0.813333	No	Yes	0	4	7
1070	H.HA.28	H.hdhe.01	0.8	No	Yes	0	3	6
1071	G.h1ha.05	H.HA.03	0.798889	No	No	0	0	8
1072	H.HA.22	H.HE.06	0.793333	No	Yes	0	7	7
1073	b.l24x3	b.lhb1x1	0.777778	Yes	No	0	5	1
1074	G.H1.10	G.s6h5.05	0.777778	No	Yes	0	0	9
1075	H.HB.10	H.HC.02	0.777778	No	No	0	1	3
1076	8x52	8x56	0.773333	No	No	0	4	5
1077	g.h1x2	g.h1x5	0.767778	No	No	0	2	6
1078	1x44	1x48	0.767778	No	No	0	5	4
1079	G.H1.11	H.HF.01	0.762222	No	No	0	0	5
1080	G.H1.10	G.h1ha.01	0.758889	No	No	0	0	0
1081	H.HC.11	H.HE.09	0.758889	No	No	0	8	5
1082	8x51	8x55	0.753333	No	No	0	8	4
1083	G.H4.10	G.H4.13	0.746667	Yes	No	0	6	3
1084	H.HB.04	H.hahb.08	0.738889	No	No	0	1	2
1085	H.HF.02	H.HF.05	0.738889	No	No	0	6	8
1086	H.hehf.01	H.hehf.03	0.733333	No	No	0	1	3
1087	H.HD.10	H.hdhe.01	0.706667	No	Yes	0	6	6
1088	g.ctx6	g.h2x16	0.702222	Yes	No	0	6	4
1089	H.HA.07	H.HF.04	0.701111	No	No	0	5	8
1090	G.HN.36	b.b5x2	0.693333	No	Yes	0	4	7
1091	6x42	6x46	0.692222	No	No	0	5	5
1092	b.1x16	b.1x20	0.688889	Yes	No	0	4	2
1093	1x40	2x62	0.688889	No	No	0	5	5
1094	g.h2x6	g.h2x7	0.684444	No	No	0	2	5
1095	4x44	4x48	0.678889	No	No	0	3	3
1096	H.HA.26	H.HD.03	0.676667	No	No	0	7	6
1097	G.s4h3.07	G.s4h3.14	0.676667	No	Yes	0	0	6
1098	1x52	8x54	0.676667	No	No	0	7	6
1099	H.HA.15	H.HE.12	0.675556	No	No	0	5	7
1100	4x51	4x52	0.675556	No	Yes	0	3	4
1101	H.HD.08	H.HD.11	0.67	No	No	0	2	6
1102	H.HA.18	H.HE.06	0.667778	No	Yes	0	7	7
1103	G.hns1.02	I2x55	0.66	No	No	0	4	4
1104	H.HA.20	H.HA.23	0.654444	No	No	0	5	4
1105	G.HN.51	G.hns1.01	0.65	No	No	0	5	3
1106	H.HD.03	H.hchd.01	0.648889	No	No	0	6	8
1107	H.HA.14	H.HE.05	0.645556	No	Yes	0	9	7
1108	4x52	4x55	0.632222	Yes	No	0	4	3
1109	1x32	1x33	0.61	No	No	0	5	4
1110	H.HA.16	H.hbhc.04	0.607778	No	No	0	4	3
1111	4x46	4x47	0.57	No	No	0	8	4
1112	6x46	6x47	0.546667	No	No	0	5	8
1113	G.HG.15	G.hgh4.06	0.525556	Yes	No	0	7	3
1114	H.hbhc.03	b.l8x4	0.516667	No	No	0	3	3
1115	6x27	6x30	0.514444	No	Yes	0	0	7
1116	H.HA.19	H.HB.11	0.512222	Yes	No	0	6	1
1117	5x73	I3	0.501111	No	Yes	3	4	3
1118	b.1x1	g.ntx2	0.5	Yes	No	0	4	0
1119	b.1x1	g.ntx3	0.5	Yes	No	0	4	0
1120	G.HN.30	G.HN.32	0.48	No	No	0	7	5
1121	H.HA.05	H.HA.08	0.478889	No	No	0	2	5
1122	H.HA.26	H.hahb.08	0.462222	No	No	0	7	2
1123	H.HE.05	H.HF.06	0.457778	Yes	Yes	0	7	6
1124	H.HE.01	H.HF.06	0.438889	No	Yes	0	8	6
1125	H.HA.10	b.l5x2	0.435556	No	Yes	0	5	6
1126	G.hfs2.02	G.hfs2.05	0.431111	No	No	0	0	0
1127	H.HA.04	H.hehf.06	0.418889	No	No	0	6	9
1128	5x45	5x48	0.412222	No	No	0	3	4
1129	b.l8x3	b.l8x6	0.404444	Yes	No	0	3	4
1130	H.hehf.05	H.hehf.06	0.376667	No	No	0	3	9
1131	1x33	1x34	0.373333	No	No	0	4	5
1132	G.h2s4.02	G.h2s4.03	0.364444	No	No	0	7	5
1133	H.hbhc.12	b.l8x5	0.363333	No	Yes	0	1	3
1134	g.h1x1	g.ntx7	0.36	No	No	0	2	4
1135	G.hfs2.04	b.l9x1	0.356667	No	No	0	0	5
1136	6x38	6x42	0.355556	No	No	0	6	5
1137	H.hehf.01	H.hehf.02	0.351111	No	No	0	1	1
1138	6x54	7x33	0.342222	No	No	0	4	3
1139	H.HD.02	H.hahb.06	0.334444	No	No	0	4	4
1140	5x75	5x76	0.333333	No	No	0	0	0
1141	H.HC.03	H.hbhc.15	0.327778	Yes	No	0	3	3
1142	H.HE.12	H.hbhc.14	0.324444	No	No	0	7	3
1143	b.ntx2	b.ntx3	0.32	No	No	0	0	5
1144	H.HF.02	H.hehf.07	0.314444	No	No	0	6	6
1145	5x59	6x41	0.314444	No	No	0	3	7
1146	g.l1x2	g.l1x3	0.311111	No	No	0	2	1
1147	G.h1ha.04	H.hehf.06	0.308889	No	No	0	0	9
1148	H.HB.03	H.HB.07	0.307778	No	No	0	3	2
1149	H.HD.07	H.HE.03	0.307778	Yes	No	0	5	3
1150	1x45	1x48	0.306667	No	No	0	4	4
1151	H.HA.29	H.hahb.05	0.301111	No	No	0	6	2
1152	H.HA.25	H.hdhe.01	0.296667	No	Yes	0	7	6
1153	H.HB.10	H.HC.06	0.291111	No	No	0	1	5
1154	H.HB.05	H.HB.08	0.29	No	No	0	3	1
1155	8x55	8x58	0.285556	No	No	0	4	6
1156	H.HA.18	H.HE.05	0.282222	No	Yes	0	7	7
1157	H.HA.11	H.HE.05	0.28	No	Yes	0	8	7
1158	H.HA.15	H.HE.05	0.277778	No	Yes	0	5	7
1159	g.ctx20	g.ctx21	0.275556	No	No	0	0	0
1160	H.HB.10	H.HC.03	0.271111	No	Yes	0	1	3
1161	H.HD.07	H.hdhe.03	0.271111	Yes	No	0	5	7
1162	H.HD.07	H.HE.06	0.271111	Yes	Yes	0	5	7
1163	H.HB.07	H.HC.10	0.27	No	No	0	2	7
1164	H.hahb.06	H.hahb.08	0.265556	No	No	0	4	2
1165	H.HA.06	b.l5x2	0.26	No	Yes	0	4	6
1166	H.hdhe.01	H.hdhe.03	0.26	Yes	No	0	6	7
1167	H.HF.02	H.HF.06	0.26	No	Yes	0	6	6
1168	H.HC.11	H.HE.07	0.251111	No	No	0	8	4
1169	H.hdhe.01	b.b13x2	0.25	Yes	No	0	6	4
1170	5x52	5x53	0.206667	No	No	0	3	5
1171	5x73	5x74	0.206667	No	No	0	4	4
1172	H.HC.04	H.HE.13	0.198889	No	No	0	4	4
1173	H.HC.05	H.HC.08	0.193333	No	No	0	1	3
1174	H.HD.06	H.HD.10	0.191111	No	No	0	5	6
1175	G.HN.30	G.HN.31	0.19	No	No	0	7	1
1176	H.HA.27	H.HA.29	0.19	No	No	0	1	6
1177	H.HB.14	H.HC.03	0.19	No	Yes	0	3	3
1178	g.ntx6	g.ntx7	0.186667	No	No	0	0	4
1179	H.HA.27	H.HB.08	0.182222	No	No	0	1	1
1180	b.l21x6	b.l21x7	0.182222	No	No	0	3	5
1181	G.hfs2.03	H.HE.01	0.18	No	No	0	0	8
1182	G.H1.09	G.h1ha.02	0.178889	No	No	0	7	0
1183	H.HC.04	H.hbhc.14	0.178889	No	No	0	4	3
1184	G.hfs2.01	H.HA.10	0.176667	No	No	0	0	5
1185	G.hfs2.01	H.HF.04	0.176667	No	No	0	0	8
1186	H.HA.21	H.hdhe.03	0.175556	No	No	0	4	7
1187	H.HE.02	H.HE.06	0.175556	No	Yes	0	7	7
1188	H.HE.03	H.HE.07	0.173333	No	No	0	3	4
1189	H.HA.20	H.HB.11	0.171111	No	No	0	5	1
1190	H.HA.22	H.HD.03	0.171111	No	No	0	7	6
1191	H.HB.05	H.HB.06	0.171111	No	No	0	3	4
1192	H.hehf.05	H.hehf.07	0.168889	No	No	0	3	6
1193	G.H4.05	G.H4.08	0.167778	Yes	No	0	4	3
1194	G.s4h3.09	G.s4h3.12	0.167778	No	No	0	0	0
1195	H.hahb.06	H.hahb.07	0.167778	No	No	0	4	3
1196	H.hbhc.01	H.hbhc.04	0.167778	No	No	0	2	3
1197	H.hbhc.12	H.hbhc.13	0.167778	No	No	0	1	1
1198	G.HN.10	G.HN.11	0.163333	No	Yes	0	4	2
1199	H.hahb.09	H.hchd.01	0.163333	No	No	0	1	8
1200	H.HA.19	H.HC.03	0.158889	Yes	Yes	21	6	3
1201	H.HA.19	H.HE.09	0.158889	Yes	No	21	6	5
1202	H.HC.03	H.HC.07	0.158889	Yes	Yes	21	3	6
1203	H.HC.07	H.HC.10	0.158889	Yes	No	0	6	7
1204	H.HC.07	H.HE.09	0.158889	Yes	No	21	6	5
1205	G.HN.38	G.HN.41	0.15	No	No	0	3	4
1206	G.HN.38	G.HN.42	0.15	No	No	0	3	4
1207	G.H1.10	G.H1.12	0.147778	No	No	0	0	0
1208	H.HE.10	H.HE.11	0.132222	No	No	0	3	8
1209	H.hdhe.01	H.hdhe.02	0.125556	Yes	No	0	6	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.11	2.20978	5	0	2
2	G.HN.43	3.89528	4	6	9
3	G.HN.47	3.54167	4	6	6
4	G.S1.02	5.22972	4	3	5
5	G.S1.05	5.7275	4	1	9
6	G.S1.06	4.43389	4	3	8
7	G.H1.01	4.99694	4	3	9
8	G.H1.08	4.77056	4	3	8
9	G.S2.06	7.56444	4	3	9
10	G.S2.08	7.445	4	3	5
11	G.S3.01	5.5425	4	3	4
12	G.S3.03	7.68533	5	3	7
13	G.S3.04	6.34533	5	1	6
14	G.S3.05	3.61467	5	3	7
15	G.S3.06	6.695	6	1	5
16	G.s3h2.03	4.034	5	1	9
17	G.H2.03	5.67556	4	1	9
18	G.H2.04	4.05528	4	0	9
19	G.H2.06	5.51381	7	1	9
20	G.H2.07	5.27111	7	1	9
21	G.h2s4.01	6.64	5	1	9
22	G.S4.02	4.07667	5	1	8
23	G.S4.04	6.00333	4	1	9
24	G.s4h3.03	5.94083	4	23	8
25	G.s4h3.04	6.20978	5	17	8
26	G.s4h3.05	5.75278	4	17	9
27	G.s4h3.14	1.09306	4	0	6
28	G.H3.01	6.25195	4	23	9
29	G.H3.09	5.98889	7	1	9
30	G.H3.13	3.76867	5	1	5
31	G.H3.14	5.11333	4	0	8
32	G.H3.17	7.85296	6	1	5
33	G.H3.18	4.94444	5	1	9
34	G.S5.03	3.15917	4	3	8
35	G.S5.04	4.12733	5	1	9
36	G.S5.05	3.55972	4	3	9
37	G.S5.07	3.8675	4	3	9
38	G.HG.04	5.90044	5	0	9
39	G.HG.15	3.59578	5	0	7
40	G.hgh4.02	6.00244	5	12	7
41	G.hgh4.05	7.26167	4	0	7
42	G.H4.03	6.04222	5	0	4
43	G.H4.05	3.49306	4	24	4
44	G.H4.10	7.74889	5	12	6
45	G.H4.15	5.54417	4	1	8
46	G.S6.02	8.18889	4	0	7
47	G.s6h5.01	6.06528	4	3	9
48	G.s6h5.02	3.46361	4	0	7
49	G.s6h5.05	2.86361	4	0	9
50	G.H5.03	7.06917	4	3	8
51	G.H5.06	8.05556	4	3	3
52	G.H5.08	6.10194	4	3	8
53	G.H5.09	3.32194	4	3	4
54	G.H5.13	8.4725	4	0	8
55	b.1x1	1.72511	5	0	4
56	b.1x16	2.56833	4	0	4
57	b.1x19	4.70667	4	0	6
58	b.h2x1	4.44361	4	0	5
59	b.lhb1x11	3.90361	4	0	4
60	b.b1x4	3.59356	5	9	7
61	b.b1x6	8.28972	4	0	9
62	b.l1x3	7.25587	7	6	9
63	b.b2x1	9.09622	5	1	8
64	b.b2x5	6.39426	6	6	7
65	b.b3x3	4.48111	4	8	8
66	b.l3x2	4.638	5	6	9
67	b.b4x3	5.24028	4	8	7
68	b.b4x4	8.76139	4	6	8
69	b.b4x6	9.79815	6	6	9
70	b.b5x2	4.44467	5	22	7
71	b.b5x3	6.3346	7	6	9
72	b.b5x5	5.71333	4	0	5
73	b.b5x7	6.22111	4	8	7
74	b.l5x1	4.61139	4	8	8
75	b.l5x2	3.93667	4	0	6
76	b.l5x5	8.37611	6	1	9
77	b.b6x5	3.97825	7	8	6
78	b.l6x5	6.2925	4	18	4
79	b.b7x1	5.94356	5	18	4
80	b.b8x3	4.53361	4	0	6
81	b.b8x4	5.28556	6	8	6
82	b.l8x1	3.97444	4	8	5
83	b.l8x3	2.80917	4	25	3
84	b.l8x5	2.48067	5	25	3
85	b.l8x8	5.16389	4	8	4
86	b.l9x3	8.06289	5	10	9
87	b.l9x6	5.17403	8	1	8
88	b.b10x3	3.65083	4	0	8
89	b.b10x5	4.2287	6	0	9
90	b.b11x2	4.15611	4	0	7
91	b.b11x4	6.32111	4	10	9
92	b.l11x2	6.84389	4	10	9
93	b.b12x3	3.5625	4	4	8
94	b.b12x6	7.88937	7	10	8
95	b.b13x7	7.63089	5	4	7
96	b.l13x3	6.16016	7	4	9
97	b.l13x6	6.31694	4	1	9
98	b.l13x7	4.67167	4	4	9
99	b.b14x3	4.98222	4	4	5
100	b.b15x1	5.93095	7	4	9
101	b.b15x2	6.41278	4	5	6
102	b.b15x3	4.55861	4	4	9
103	b.l15x1	5.11194	4	1	7
104	b.l15x2	5.53889	4	4	9
105	b.b16x4	10.2669	4	4	6
106	b.b16x5	4.92028	4	0	5
107	b.b16x6	8.64593	6	4	8
108	b.b17x5	7.63306	4	5	7
109	b.b17x7	8.48306	4	5	8
110	b.l17x3	7.54952	7	5	9
111	b.l17x6	7.28083	4	1	9
112	b.b18x3	4.10417	4	5	8
113	b.l18x1	6.22426	6	15	6
114	b.l18x2	5.325	4	15	7
115	b.b19x2	6.85574	6	5	6
116	b.b19x4	6.34361	4	5	8
117	b.l19x2	6.17733	5	5	9
118	b.b20x4	10.5642	5	5	8
119	b.b20x6	6.99741	6	5	6
120	b.b21x1	9.87695	4	5	7
121	b.b21x5	5.40306	4	0	4
122	b.b21x7	6.91533	5	0	5
123	b.l21x2	4.88167	4	0	4
124	b.b22x5	5.07482	6	15	7
125	b.l22x5	7.08822	5	14	9
126	b.b23x1	3.83861	4	0	5
127	b.b23x6	7.34704	6	16	7
128	b.l23x1	7.39806	4	1	6
129	b.b24x4	7.19861	4	16	6
130	b.b24x6	6.65167	4	16	8
131	b.l24x3	3.38	4	0	5
132	b.b25x3	6.40806	4	16	5
133	b.l25x3	9.03667	5	13	9
134	b.l25x6	12.4528	4	1	8
135	b.l28x1	11.2229	7	1	9
136	b.l28x2	6.84556	4	13	9
137	b.b28x3	4.75278	4	0	7
138	b.b28x4	8.36528	4	13	6
139	b.b28x6	8.44378	5	13	9
140	b.b28x7	5.51833	4	9	9
141	g.l1x4	5.74667	4	0	8
142	g.h2x11	9.04222	4	15	6
143	g.ctx3	7.43861	4	0	9
144	g.ctx6	4.01622	5	0	6
145	g.ctx14	5.49056	4	9	9
146	g.ctx15	7.08833	4	9	9
147	g.ctx16	4.77642	9	9	8
148	NT	8.38556	9	2	5
149	1x42	2.59244	5	0	6
150	1x50	4.67917	4	0	9
151	2x40	5.57698	7	7	8
152	2x46	4.32056	4	11	9
153	2x50	5.84083	4	0	9
154	2x51	3.22111	4	0	7
155	2x57	5.48407	6	2	6
156	2x64	6.86844	5	2	3
157	2x65	5.88933	5	2	4
158	E1	4.36889	8	2	4
159	3x25	5.58083	4	2	9
160	3x33	5.29917	4	2	4
161	3x36	4.50956	5	2	6
162	3x44	3.8925	4	0	6
163	3x49	5.88556	4	0	9
164	3x50	7.41361	4	11	9
165	3x55	8.77222	4	20	6
166	I2x53	6.53426	6	7	7
167	4x50	5.01333	4	27	9
168	4x52	0.973056	4	0	4
169	E2	12.7386	20	2	5
170	5x39	5.398	5	2	7
171	5x43	6.66	6	2	5
172	5x50	3.0375	4	0	7
173	5x51	4.76028	4	0	7
174	5x58	5.81537	6	11	9
175	5x60	6.28528	4	20	5
176	5x64	3.71361	4	20	6
177	I3	3.83315	6	3	3
178	6x30	4.37611	4	0	7
179	6x48	5.28311	5	2	8
180	E3	5.83111	4	2	1
181	7x34	6.68833	4	2	4
182	7x47	4.14806	4	0	6
183	7x52	3.45278	4	0	9
184	7x53	5.18352	6	11	9
185	8x49	4.40067	5	7	6
186	Lig	7.94794	14	2	0
187	H.HA.19	0.452778	4	21	6
188	H.HC.03	0.221333	5	21	3
189	H.HC.07	0.364444	4	21	6
190	H.HD.07	0.509444	4	0	5
191	H.hdhe.01	0.406481	6	0	6
192	H.HE.05	0.388667	5	0	7
193	H.HE.06	0.476944	4	0	7
194	H.HF.06	0.660833	4	0	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.37	G.HN.41	23.0329	4.21556	No	No	0	3	4
2	G.HN.37	b.b5x2	23.4765	4.59667	No	Yes	0	3	7
3	G.HN.38	G.HN.41	22.9834	0.15	No	No	0	3	4
4	G.HN.38	G.HN.42	22.9379	0.15	No	No	0	3	4
5	G.HN.42	G.HN.45	22.9027	2.75556	No	No	0	4	4
6	G.HN.45	G.HN.48	22.8432	1.30444	No	No	0	4	3
7	G.HN.48	G.HN.52	22.8338	1.80778	No	No	0	3	4
8	G.HN.52	I2x55	22.8269	3.08778	No	No	0	4	4
9	G.hns1.03	I2x55	22.8647	6.78444	No	No	0	4	4
10	b.b4x7	b.b5x2	20.3633	2.84333	No	Yes	22	8	7
11	b.b4x7	b.l2x5	20.504	14.0267	No	No	0	8	5
12	b.l2x5	b.l4x2	15.3081	24.8078	No	No	0	5	4
13	b.b28x7	b.lhb1x11	10.0457	2.96	Yes	Yes	0	9	4
14	b.b25x7	b.lhb1x11	10.9839	5.33778	No	Yes	0	7	4
15	b.b25x7	b.b28x6	11.0289	14.9333	No	Yes	0	7	9
16	b.b27x3	b.b28x6	10.0748	9.29889	No	Yes	0	8	9
17	b.b26x3	b.b27x3	11.4012	4.75	No	No	0	6	8
18	b.b22x2	b.b26x3	11.4697	6.17333	No	No	0	8	6
19	b.b22x1	b.b22x2	11.5438	2.84444	No	No	0	8	8
20	b.b22x1	b.l25x6	11.2461	4.59889	No	Yes	1	8	8
21	G.hns1.03	I2x52	22.8764	3.81444	No	No	0	4	5
22	3x56	I2x52	22.9168	2.01333	No	No	0	5	5
23	3x55	3x56	23.0611	16.1	Yes	No	0	6	5
24	3x55	5x64	23.1639	3.72	Yes	Yes	20	6	6
25	3x54	5x64	24.1668	3.19222	No	Yes	0	9	6
26	3x54	G.H5.20	24.5145	3.73667	No	No	0	9	9
27	G.H5.20	G.H5.26	76.4983	8.25667	No	No	0	9	5
28	6x29	G.H5.26	77.336	3.28556	No	No	0	5	5
29	6x29	G.H5.17	80.1945	2.84333	No	No	0	5	5
30	G.H5.13	G.H5.17	44.0463	11.2144	Yes	No	0	8	5
31	G.S3.01	I2x51	14.5477	4.96556	Yes	No	0	4	7
32	G.S3.01	G.S3.03	14.0585	7.98444	Yes	Yes	3	4	7
33	G.H5.13	G.S6.02	37.4982	9.57667	Yes	Yes	0	8	7
34	G.H5.10	G.S6.02	74.6406	5.19	No	Yes	0	6	7
35	G.H5.10	G.S5.03	74.7811	3.78889	No	Yes	0	6	8
36	G.S5.03	G.S5.05	38.3214	2.93	Yes	Yes	3	8	9
37	G.S4.03	G.S5.05	22.215	2.93	No	Yes	0	7	9
38	G.S1.04	G.S4.03	17.303	5.55	No	No	0	7	7
39	G.H5.17	G.h4s6.12	36.5682	3.9	No	No	0	5	4
40	G.S6.02	G.h4s6.12	36.7429	14.34	Yes	No	0	7	4
41	G.H3.17	b.l25x6	28.9797	4.77778	Yes	Yes	1	5	8
42	G.H3.15	G.H3.17	34.4218	4.77111	No	Yes	1	8	5
43	G.H3.15	G.H3.18	17.1551	3.62444	No	Yes	1	8	9
44	G.H3.18	G.S4.02	17.4584	7.53444	Yes	Yes	1	9	8
45	G.S5.05	G.s6h5.01	57.1015	5.04444	Yes	Yes	3	9	9
46	G.S5.06	G.s4h3.01	52.7979	6.91889	No	No	0	8	7
47	G.S5.04	G.S5.06	99.6223	4.30556	Yes	No	0	9	8
48	G.S4.04	G.S5.04	78.656	3.38111	Yes	Yes	1	9	9
49	G.H3.08	G.S4.04	86.8971	5.54889	No	Yes	0	9	9
50	G.H2.04	G.H3.08	86.7668	3.50778	Yes	No	0	9	9
51	G.H2.04	G.H2.08	18.1657	4.31444	Yes	No	0	9	8
52	G.H2.08	G.H3.15	17.7223	2.98889	No	No	1	8	8
53	G.H3.09	G.S5.04	22.7334	4.60333	Yes	Yes	1	9	9
54	G.H3.09	G.S5.02	22.928	5.30111	Yes	No	1	9	6
55	G.S4.02	G.S5.02	23.9938	3.10667	Yes	No	1	8	6
56	G.H5.03	G.S6.04	39.2185	3.11778	Yes	No	3	8	9
57	G.H5.06	G.S6.04	39.0307	20.1133	Yes	No	3	3	9
58	G.H5.06	G.S5.03	37.0632	3.21	Yes	Yes	3	3	8
59	G.H5.03	G.s6h5.01	58.1037	10.0733	Yes	Yes	3	8	9
60	G.H2.04	G.H2.07	76.0289	4.44444	Yes	Yes	0	9	9
61	G.H2.07	b.l9x6	72.0728	5.57444	Yes	Yes	1	9	8
62	G.H2.06	b.l9x6	71.5385	3.58	Yes	Yes	1	9	8
63	G.H2.06	b.l17x6	35.4869	8.45	Yes	Yes	1	9	9
64	G.H2.06	b.b18x1	35.4871	4.19889	Yes	No	0	9	9
65	G.HG.04	G.s4h3.01	51.0748	11.5022	Yes	No	0	9	7
66	G.H3.06	G.hgh4.02	11.9377	5.45444	No	Yes	0	6	7
67	G.S5.06	G.S6.05	46.9062	7.44555	No	No	0	8	4
68	G.H4.03	G.HG.04	52.8154	3.44	Yes	Yes	0	4	9
69	G.H4.03	G.H4.07	47.4275	3.55889	Yes	No	0	4	5
70	G.H4.07	G.S6.05	47.4772	3.69667	No	No	0	5	4
71	G.H4.03	G.HG.01	100	6.50222	Yes	No	0	4	5
72	G.H5.03	G.s6h5.05	97.899	6.43222	Yes	Yes	0	8	9
73	G.s6h5.02	G.s6h5.05	98.9322	2.24667	Yes	Yes	0	7	9
74	G.H5.15	I2x51	20.0329	3.20889	No	No	0	7	7
75	G.H5.15	G.H5.19	19.8473	3.46333	No	No	0	7	8
76	G.H5.19	I2x53	11.2898	12.5333	No	Yes	7	8	7
77	G.H5.20	G.H5.25	80.3188	3.84444	No	No	0	9	7
78	2x37	G.H5.22	16.0297	6.59	No	No	7	6	4
79	3x50	G.H5.25	79.3038	12.1467	Yes	No	0	9	7
80	b.l2x3	b.l2x5	25.3308	2.90889	No	No	0	8	5
81	b.b3x1	b.l2x3	25.2875	5.73222	No	No	0	5	8
82	b.b3x1	b.b6x5	25.2479	4.55778	No	Yes	0	5	6
83	b.b2x4	b.b6x5	27.9077	3.14889	No	Yes	0	6	6
84	b.b10x4	b.b2x4	27.8495	11.16	No	No	0	6	6
85	b.b10x4	b.b14x5	19.8381	3.64333	No	No	0	6	5
86	b.b14x5	b.b15x1	14.5514	3.11333	No	Yes	0	5	9
87	b.b15x1	b.b16x6	20.2973	12.6956	Yes	Yes	4	9	8
88	b.b16x4	b.b16x6	17.1067	8.24889	Yes	Yes	4	6	8
89	b.b16x4	b.b17x6	18.3909	12.3456	Yes	No	0	6	7
90	b.b17x6	g.h1x14	18.45	6.42889	No	No	0	7	9
91	b.1x15	g.h1x14	35.658	3.49222	No	No	0	7	9
92	b.1x15	b.1x19	35.7149	4.87222	No	Yes	0	7	6
93	b.b16x6	b.b17x3	17.1096	5.80444	Yes	No	4	8	5
94	b.b17x3	g.h1x10	17.1521	4.91667	No	No	0	5	9
95	g.h1x10	g.h1x14	17.21	5.94556	No	No	0	9	9
96	b.1x19	b.b21x1	36.9647	9.39556	Yes	Yes	0	6	7
97	b.b10x2	b.b6x2	19.4148	2.81667	No	No	0	6	8
98	b.b10x3	b.b6x2	19.2252	4.69444	Yes	No	0	8	8
99	b.b10x3	b.b11x2	11.6238	3.09111	Yes	Yes	0	8	7
100	b.b7x1	b.b8x3	11.5918	3.63	Yes	Yes	0	4	6
101	b.b10x2	b.b14x3	12.1413	3.52556	No	Yes	0	6	5
102	b.b12x7	b.b13x4	24.6291	2.41222	No	No	0	9	4
103	b.b13x5	b.b13x7	20.0769	6.05333	No	Yes	4	4	7
104	b.b13x4	b.b13x5	19.4462	3.66333	No	No	4	4	4
105	b.b12x7	b.l12x3	23.7591	6.90667	No	No	0	9	5
106	b.b17x7	b.b21x1	34.6623	4.64444	Yes	Yes	5	8	7
107	b.b16x5	b.l14x6	15.822	5.22667	Yes	No	0	5	3
108	b.b17x7	b.b20x6	39.5076	10.5989	Yes	Yes	5	8	6
109	b.b20x6	b.l17x3	53.6288	3.39667	Yes	Yes	5	6	9
110	b.b16x7	b.l14x6	13.8448	3.77	No	No	0	9	3
111	b.l17x3	b.l19x2	66.3784	3.92	Yes	Yes	5	9	9
112	b.l17x5	b.l19x2	70.0957	3.76333	No	Yes	0	6	9
113	b.l17x5	b.l19x1	70.5278	4.08889	No	No	0	6	9
114	b.l17x6	b.l19x1	35.6817	7.68667	Yes	No	0	9	9
115	b.b18x1	b.l19x1	35.2902	10.77	No	No	0	9	9
116	b.l21x7	b.l23x1	18.2714	5.53444	No	Yes	0	5	6
117	b.l21x7	b.l23x2	17.317	7.60667	No	No	0	5	8
118	b.b23x6	b.l23x2	14.965	3.83333	Yes	No	0	7	8
119	3x50	7x53	72.8861	7.65889	Yes	Yes	11	9	9
120	2x46	7x53	69.9665	2.99556	Yes	Yes	11	9	9
121	2x46	7x49	67.2369	3.51	Yes	No	0	9	9
122	7x45	7x49	55.9006	9.83889	No	No	0	9	9
123	6x48	7x45	52.7605	5.39889	Yes	No	0	8	9
124	3x36	6x48	43.1681	5.23444	Yes	Yes	2	6	8
125	3x36	Lig	37.3817	4.24667	Yes	Yes	2	6	0
126	E2	Lig	13.9988	29.9044	Yes	Yes	2	5	0
127	1x50	2x50	10.2151	8.67778	Yes	Yes	0	9	9
128	2x50	7x49	11.3254	3.88889	Yes	No	0	9	9
129	b.b13x2	b.l12x3	23.4688	2.67556	No	No	0	4	5
130	H.hdhe.01	b.b13x2	23.1712	0.25	Yes	No	0	6	4
131	H.hdhe.01	H.hdhe.03	21.2403	0.26	Yes	No	0	6	7
132	H.HD.07	H.hdhe.03	20.6886	0.271111	Yes	No	0	5	7
133	H.HD.07	H.HE.06	11.0339	0.271111	Yes	Yes	0	5	7
134	G.HG.01	G.s6h5.02	99.7819	5.56889	No	Yes	0	5	7
135	G.S1.04	G.S3.03	15.0192	2.97667	No	Yes	0	7	7
136	b.l23x1	b.l25x6	18.528	18	Yes	Yes	1	6	8
137	b.b14x3	b.b15x1	11.8606	6.09111	Yes	Yes	4	5	9
138	b.b13x7	b.b16x6	14.3046	14.3644	Yes	Yes	4	7	8
139	b.b19x2	b.b20x6	13.969	10.9578	Yes	Yes	5	6	6

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
NT	NT	9.64444	2	Yes	Yes	5	5	2	2
2x64	NT	8.49778	2	Yes	Yes	3	5	1	2
E2	NT	16.1033	2	Yes	Yes	5	5	1	2
2x65	NT	5.32222	2	Yes	Yes	4	5	1	2
7x31	NT	6.93111	2	No	Yes	2	5	2	2
2x57	2x61	7.14333	2	Yes	No	6	6	1	1
2x57	3x32	4.51444	2	Yes	No	6	5	1	1
2x57	3x36	3.93	2	Yes	Yes	6	6	1	1
2x57	7x38	3.96222	2	Yes	No	6	5	1	1
2x57	7x42	4.19556	2	Yes	No	6	6	1	2
2x57	Lig	9.15889	2	Yes	Yes	6	0	1	0
2x60	3x28	6.46	0	No	No	4	5	1	2
2x60	Lig	3.98667	0	No	Yes	4	0	1	0
2x61	2x65	11.0622	2	No	Yes	6	4	1	1
2x61	Lig	3.70111	2	No	Yes	6	0	1	0
2x64	2x65	8.42	2	Yes	Yes	3	4	1	1
2x64	E1	3.47222	2	Yes	Yes	3	4	1	2
2x64	Lig	10.8567	2	Yes	Yes	3	0	1	0
2x65	Lig	3.50333	2	Yes	Yes	4	0	1	0
3x25	E1	3.58667	2	Yes	Yes	9	4	2	2
3x28	E1	3.09111	0	No	Yes	5	4	2	2
3x22	E2	10.36	0	No	Yes	3	5	2	1
3x25	3x29	5.40444	2	Yes	No	9	4	2	1
3x25	E2	10.2367	2	Yes	Yes	9	5	2	1
3x26	4x60	3.28444	2	No	No	5	5	2	2
3x26	E2	4.00556	2	No	Yes	5	5	2	1
3x29	E2	5.19333	2	No	Yes	4	5	1	1
3x29	Lig	5.59111	2	No	Yes	4	0	1	0
3x32	Lig	4.00222	2	No	Yes	5	0	1	0
3x33	4x57	3.74889	2	Yes	No	4	7	1	2
3x33	Lig	10.3056	2	Yes	Yes	4	0	1	0
3x36	6x48	5.23444	2	Yes	Yes	6	8	1	2
3x36	7x41	6.51778	2	Yes	No	6	7	1	2
3x36	Lig	4.24667	2	Yes	Yes	6	0	1	0
3x37	5x43	5.65889	0	No	Yes	6	5	2	1
4x59	E2	4.05	0	No	Yes	5	5	2	1
4x60	5x39	10.3522	0	No	Yes	5	7	2	1
5x36	E2	17.0322	2	No	Yes	4	5	2	1
5x38	E2	6.16778	2	No	Yes	4	5	2	1
5x39	E2	7.75222	2	Yes	Yes	7	5	1	1
E2	E2	43.6533	2	Yes	Yes	5	5	1	1
5x37	E2	6.25333	2	No	Yes	4	5	2	1
5x40	E2	6.32556	0	No	Yes	5	5	2	1
E2	E3	12.0489	2	Yes	Yes	5	1	1	2
7x31	E2	4.25778	2	No	Yes	2	5	2	1
6x58	E2	10.0333	0	No	Yes	3	5	2	1
7x34	E2	12.0878	2	Yes	Yes	4	5	1	1
6x55	E2	3.51222	2	No	Yes	6	5	2	1
E2	Lig	29.9044	2	Yes	Yes	5	0	1	0
5x39	5x43	4.07111	2	Yes	Yes	7	5	1	1
5x39	Lig	3.30556	2	Yes	Yes	7	0	1	0
5x43	5x47	10.9389	2	Yes	No	5	7	1	2
5x43	6x55	3.87667	2	Yes	No	5	6	1	2
5x43	Lig	11.1033	2	Yes	Yes	5	0	1	0
6x48	7x41	6.38667	2	Yes	No	8	7	2	2
6x54	7x34	6.30556	0	No	Yes	4	4	2	1
7x34	Lig	5.52	2	Yes	Yes	4	0	1	0
7x38	Lig	6.08556	2	No	Yes	5	0	1	0
E1	NT	10.2322	2	Yes	Yes	4	5	2	2
2x64	3x25	3.09556	2	Yes	Yes	3	9	1	2
3x33	5x43	4.31111	2	Yes	Yes	4	5	1	1
5x36	5x38	2.96444	2	No	No	4	4	2	2
6x51	7x34	2.84	0	No	Yes	6	4	2	1
3x30	3x33	2.83111	0	No	Yes	6	4	2	1
2x53	3x36	2.61889	0	No	Yes	8	6	2	1
4x63	E2	2.14	0	No	Yes	4	5	2	1
5x39	5x42	1.50889	2	Yes	No	7	5	1	2
2x65	7x35	1.13889	2	Yes	No	4	4	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
100.00	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
85.71	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
85.71	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
80.00	Single	5XR8	AM841	5XR8-CB₁-AM841
80.00	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
78.57	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
78.57	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
75.00	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
73.33	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
73.33	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
72.22	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
71.43	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
71.43	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
70.59	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
70.59	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
68.75	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
66.67	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
66.67	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
66.67	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
64.71	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
64.71	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
64.71	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
61.11	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
60.00	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
58.82	Single	5XRA	AM11542	5XRA-CB₁-AM11542
58.82	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
57.89	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
57.89	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
48.00	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
47.62	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
47.37	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
47.37	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
47.06	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
47.06	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
47.06	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
47.06	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
45.45	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
44.44	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
44.44	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
44.44	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
44.44	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
44.44	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
43.75	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
43.48	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
42.86	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
42.86	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
42.86	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
42.86	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
42.11	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
42.11	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
42.11	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
42.11	Single	8E0G	BU72	8E0G-μ-BU72
42.11	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
41.18	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
41.18	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
41.18	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
41.18	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
41.18	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
41.18	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
41.18	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
41.18	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
40.91	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
40.00	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
40.00	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
40.00	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
40.00	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
40.00	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
40.00	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
39.13	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
39.13	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
39.13	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
39.13	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
38.89	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
38.89	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
38.89	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
38.89	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
38.89	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
38.89	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
38.89	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
38.89	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
38.46	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
38.10	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
38.10	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
38.10	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
38.10	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
38.10	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
38.10	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
38.10	Consensus	orexin_on	Orthosteric Ligand	ox2_on
38.10	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
37.50	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
37.50	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
37.50	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
37.50	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
37.50	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
37.50	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
37.50	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
37.50	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
37.50	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
37.50	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
37.04	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
36.84	Single	5C1M	BU72	5C1M-μ-BU72
36.84	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
36.84	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
36.84	Single	7C4S	S1P	7C4S-S1P₃-S1P
36.84	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
36.84	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
36.84	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
36.84	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
36.84	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
36.84	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
36.84	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
36.36	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
36.36	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
36.36	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
36.36	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
36.36	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
36.36	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
36.36	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
36.36	Consensus	class-d_off	Orthosteric Ligand	ste2_off
36.36	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
36.00	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
36.00	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
35.71	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
35.71	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
35.48	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
35.29	Single	6AKX	A4R	6AKX-CCR5-A4R
35.29	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
35.29	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
35.29	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
35.29	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
35.29	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
35.29	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
35.29	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
35.29	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
35.00	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
35.00	Single	4DJH	JDTic	4DJH-κ-JDTic
35.00	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
35.00	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
35.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
35.00	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
35.00	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
35.00	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
35.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
35.00	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
35.00	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
35.00	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
35.00	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
35.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
35.00	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
35.00	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
35.00	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
35.00	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
35.00	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
35.00	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
35.00	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
35.00	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
35.00	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
34.78	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
34.78	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
34.78	Single	7QA8	Peptide	7QA8-STE2-Peptide
34.78	Single	7QA8	Peptide	7QA8-STE2-Peptide
34.78	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
34.78	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
34.78	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
34.78	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
34.78	Consensus	class-d_off	Orthosteric Ligand	ste2_off
34.78	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
34.78	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
34.78	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
34.78	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
34.78	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
34.62	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
34.48	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
34.38	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
33.33	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
33.33	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
33.33	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
33.33	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
33.33	Single	6TPG	EMPA	6TPG-OX₂-EMPA
33.33	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
33.33	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
33.33	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
33.33	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
33.33	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
33.33	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
33.33	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
33.33	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
33.33	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
33.33	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
33.33	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
33.33	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
33.33	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
33.33	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
33.33	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
33.33	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
33.33	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
33.33	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
33.33	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
33.33	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
33.33	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
33.33	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
33.33	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
33.33	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
33.33	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
33.33	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
33.33	Consensus	hcar_on	Orthosteric Ligand	hca_on
33.33	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
33.33	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
33.33	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
33.33	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
33.33	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
33.33	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
33.33	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
32.35	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
32.35	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
32.14	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
32.14	Consensus	go_class-b1	Orthosteric Ligand	go_crf
32.14	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
32.00	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
32.00	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
32.00	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
32.00	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
32.00	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
31.82	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
31.82	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
31.82	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
31.82	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
31.82	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
31.82	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
31.82	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
31.82	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
31.82	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
31.82	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
31.82	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
31.82	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
31.82	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
31.82	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
31.82	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
31.82	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
31.82	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
31.82	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
31.82	Consensus	endothelin_off	Orthosteric Ligand	etb_off
31.82	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
31.82	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
31.58	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
31.58	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
31.58	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
31.58	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
31.58	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
31.58	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
31.58	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
31.58	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
31.58	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
31.58	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
31.58	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
31.58	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
31.58	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
31.58	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
31.58	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
31.58	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
31.58	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
31.58	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
31.58	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
31.58	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
31.58	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
31.58	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
31.58	Consensus	blt_on	Orthosteric Ligand	blt1_on
31.58	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
31.58	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
31.58	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
31.58	Consensus	leuko_on	Orthosteric Ligand	blt_on
31.58	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
31.58	Consensus	tar_on	Orthosteric Ligand	ta1_on
31.25	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
31.25	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
31.25	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
31.25	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
31.25	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
31.25	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
31.03	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
31.03	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
31.03	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
31.03	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
30.77	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
30.77	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
30.77	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
30.77	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
30.77	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
30.77	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.77	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
30.77	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
30.77	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
30.77	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
30.43	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
30.43	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
30.43	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
30.43	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
30.43	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
30.43	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
30.43	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
30.43	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
30.43	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
30.43	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
30.43	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
30.43	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
30.00	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
30.00	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
30.00	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
30.00	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
30.00	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
30.00	Single	5WQC	EMPA	5WQC-OX₂-EMPA
30.00	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
30.00	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
30.00	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
30.00	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
30.00	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
30.00	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
30.00	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
30.00	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
30.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
30.00	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
30.00	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
30.00	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
30.00	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
30.00	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
30.00	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
30.00	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
30.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
30.00	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
30.00	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
30.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
30.00	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
30.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
30.00	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.00	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
30.00	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
30.00	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
30.00	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
30.00	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
30.00	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
30.00	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
30.00	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
29.73	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
29.63	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.63	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
29.63	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
29.63	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
29.63	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
29.63	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
29.63	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
29.63	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
29.63	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
29.63	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
29.63	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
29.63	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
29.41	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
29.41	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
29.41	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
29.41	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
29.41	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
29.41	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
29.41	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
29.41	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
29.41	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
29.41	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
29.41	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
29.41	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
29.41	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
29.41	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.41	Consensus	class-t_on	Orthosteric Ligand	taste2_on
29.41	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
29.41	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
29.41	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
29.17	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
29.17	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
29.17	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.17	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
29.17	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
29.17	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
29.17	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
29.17	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
29.17	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
29.17	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
29.17	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
29.17	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
29.03	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
29.03	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
29.03	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
28.57	Single	2YDV	NECA	2YDV-A_2A-NECA
28.57	Single	3P0G	BI167107	3P0G-β₂-BI167107
28.57	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
28.57	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
28.57	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
28.57	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
28.57	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
28.57	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
28.57	Single	5G53	NECA	5G53-A_2A-NECA-Gs
28.57	Single	5X93	K-8794	5X93-ET_B-K-8794
28.57	Single	6FJ3	PTH	6FJ3-PTH1-PTH
28.57	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
28.57	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
28.57	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
28.57	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
28.57	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
28.57	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
28.57	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
28.57	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
28.57	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
28.57	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
28.57	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
28.57	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
28.57	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
28.57	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
28.57	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
28.57	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
28.57	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
28.57	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
28.57	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
28.57	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
28.57	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
28.57	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
28.57	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
28.57	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
28.57	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
28.57	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
28.57	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
28.57	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
28.57	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
28.57	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
28.57	Consensus	class-d_on	Orthosteric Ligand	ste2_on
28.57	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
28.57	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
28.57	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
28.57	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
28.57	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
28.57	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
28.57	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
28.57	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
28.57	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
28.57	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
28.57	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
28.12	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
28.00	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
28.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
28.00	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
28.00	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
28.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
28.00	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
28.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
27.78	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
27.78	Single	5WS3	EMPA	5WS3-OX₂-EMPA
27.78	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
27.78	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
27.78	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
27.78	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
27.78	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
27.78	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
27.78	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.78	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
27.78	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
27.78	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
27.78	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
27.78	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
27.78	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
27.78	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
27.78	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
27.78	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
27.78	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
27.78	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
27.78	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
27.78	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
27.78	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
27.78	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
27.78	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
27.78	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
27.78	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
27.78	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.78	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
27.78	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
27.78	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.78	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
27.78	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
27.78	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
27.59	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
27.59	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
27.59	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
27.59	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
27.59	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
27.59	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
27.59	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
27.27	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
27.27	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
27.27	Single	4LDE	BI167107	4LDE-β₂-BI167107
27.27	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
27.27	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
27.27	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
27.27	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
27.27	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
27.27	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
27.27	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
27.27	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
27.27	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
27.27	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
27.27	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
27.27	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
27.27	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
27.27	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
27.27	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
27.27	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
27.27	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
27.27	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
27.27	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
27.27	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.27	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
27.27	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
27.27	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
27.27	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
27.27	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
27.27	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
27.27	Consensus	dp_off	Orthosteric Ligand	dp2_off
27.27	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
27.27	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
27.27	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
27.27	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
27.27	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
27.27	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
27.27	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
27.27	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
27.27	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
27.27	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
27.27	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
27.27	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
26.92	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
26.92	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
26.92	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
26.92	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
26.92	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
26.92	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
26.92	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
26.92	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
26.92	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.92	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
26.67	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
26.67	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
26.67	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
26.67	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
26.67	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
26.67	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
26.67	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
26.67	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
26.67	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
26.67	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
26.32	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
26.32	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
26.32	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
26.32	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
26.32	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
26.32	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
26.32	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
26.32	Single	6VI4	JDTic	6VI4-κ-JDTic
26.32	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
26.32	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
26.32	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
26.32	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
26.32	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
26.32	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
26.32	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
26.32	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
26.32	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.32	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
26.32	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
26.32	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
26.32	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
26.32	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.32	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.32	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
26.32	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
26.32	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
26.32	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
26.32	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
26.32	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
26.32	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
26.32	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
26.32	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
26.32	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
26.32	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
26.32	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
26.32	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
26.32	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
26.32	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
26.32	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
26.32	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
26.32	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
26.32	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.32	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.32	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
26.32	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
26.32	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
26.32	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
26.32	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
26.32	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
26.32	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
26.32	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
26.32	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
26.32	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
26.32	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
26.09	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
26.09	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
26.09	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
26.09	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
26.09	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
26.09	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
26.09	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
26.09	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
26.09	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
26.09	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
26.09	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
26.09	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
26.09	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
26.09	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
26.09	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
26.09	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
26.09	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
26.09	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
26.09	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
26.09	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
25.93	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
25.93	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
25.93	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
25.93	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
25.93	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
25.93	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
25.81	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
25.81	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
25.81	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
25.81	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
25.81	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
25.00	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
25.00	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
25.00	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
25.00	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
25.00	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
25.00	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
25.00	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
25.00	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
25.00	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
25.00	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
25.00	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
25.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
25.00	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
25.00	Single	6GPS	MK0812	6GPS-CCR2-MK0812
25.00	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
25.00	Single	6IIV	Daltroban	6IIV-TP-Daltroban
25.00	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
25.00	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
25.00	Single	6PS1	Timolol	6PS1-β₂-Timolol
25.00	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
25.00	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
25.00	Single	6PT3	DPI-287	6PT3-δ-DPI-287
25.00	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
25.00	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
25.00	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
25.00	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
25.00	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
25.00	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
25.00	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
25.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
25.00	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
25.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
25.00	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
25.00	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
25.00	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
25.00	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
25.00	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
25.00	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
25.00	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
25.00	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
25.00	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
25.00	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
25.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
25.00	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
25.00	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
25.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
25.00	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
25.00	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
25.00	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
25.00	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
25.00	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
25.00	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
25.00	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
25.00	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
25.00	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
25.00	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
25.00	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
25.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
25.00	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
25.00	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
25.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
25.00	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
25.00	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
25.00	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
25.00	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
25.00	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
25.00	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
25.00	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
25.00	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
25.00	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
25.00	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
25.00	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
25.00	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
25.00	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
25.00	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
25.00	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
25.00	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
25.00	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
25.00	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
25.00	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
25.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
25.00	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
25.00	Consensus	hcar_off	Orthosteric Ligand	succinate_off
25.00	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
25.00	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
25.00	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
25.00	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
25.00	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
24.32	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
24.24	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
24.24	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
24.14	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
24.14	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
24.14	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
24.14	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
24.14	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
24.00	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
24.00	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
24.00	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
24.00	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
24.00	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
24.00	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
24.00	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
24.00	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
24.00	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
24.00	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.00	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
23.81	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
23.81	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
23.81	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
23.81	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
23.81	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
23.81	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
23.81	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
23.81	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
23.81	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
23.81	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
23.81	Single	6GPX	MK0812	6GPX-CCR2-MK0812
23.81	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
23.81	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
23.81	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
23.81	Single	6PS6	Timolol	6PS6-β₂-Timolol
23.81	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
23.81	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
23.81	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
23.81	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
23.81	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
23.81	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
23.81	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
23.81	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
23.81	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
23.81	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
23.81	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
23.81	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
23.81	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
23.81	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
23.81	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
23.81	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
23.81	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
23.81	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
23.81	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
23.81	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
23.81	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
23.81	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
23.81	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
23.81	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
23.81	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
23.81	Consensus	ep_off	Orthosteric Ligand	ep4_off
23.81	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
23.81	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
23.53	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
23.53	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
23.53	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
23.53	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
23.53	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
23.53	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
23.53	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
23.53	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
23.53	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.53	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
23.53	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
23.53	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
23.33	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
23.33	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
23.33	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
23.33	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
23.33	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.33	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
23.33	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
23.33	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
23.33	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
23.33	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
23.33	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
23.08	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
23.08	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
23.08	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
23.08	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
23.08	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
23.08	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
23.08	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
22.86	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
22.73	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
22.73	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
22.73	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
22.73	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
22.73	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
22.73	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
22.73	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
22.73	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
22.73	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
22.73	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
22.73	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
22.73	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
22.73	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
22.73	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
22.73	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
22.73	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.73	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
22.73	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
22.73	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
22.73	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
22.73	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
22.73	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
22.73	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
22.73	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
22.73	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
22.73	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.73	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
22.73	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
22.73	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
22.73	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
22.73	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
22.73	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
22.73	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
22.73	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
22.73	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
22.73	Consensus	histamine_off	Orthosteric Ligand	h1_off
22.73	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
22.73	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
22.73	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
22.73	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
22.73	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
22.73	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
22.58	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
22.58	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
22.58	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
22.58	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
22.58	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
22.58	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
22.58	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
22.22	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
22.22	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
22.22	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
22.22	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
22.22	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
22.22	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
22.22	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
22.22	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
22.22	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
22.22	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
22.22	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
22.22	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
22.22	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
22.22	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
22.22	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
22.22	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
22.22	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
22.22	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
22.22	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
22.22	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
22.22	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
22.22	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
21.88	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
21.74	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
21.74	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
21.74	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
21.74	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
21.74	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
21.74	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
21.74	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
21.74	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
21.74	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
21.74	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
21.74	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
21.74	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
21.74	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
21.74	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
21.74	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
21.74	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.74	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
21.74	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
21.74	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.74	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.74	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
21.74	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
21.74	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
21.74	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
21.74	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
21.74	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
21.74	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
21.74	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
21.74	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
21.74	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
21.74	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
21.74	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
21.74	Consensus	blt_off	Orthosteric Ligand	blt1_off
21.74	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
21.74	Consensus	gi_class-f	Other Ligand	gi_frizzled
21.74	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
21.74	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
21.74	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
21.74	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
21.43	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
21.43	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
21.43	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
21.43	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
21.43	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
21.43	Consensus	class-d_on	Orthosteric Ligand	ste2_on
21.43	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
21.43	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
21.43	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
21.43	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.43	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
21.21	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
21.21	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
21.05	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
21.05	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
21.05	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
21.05	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
21.05	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
21.05	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
21.05	Single	5U09	Taranabant	5U09-CB₁-Taranabant
21.05	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
21.05	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
21.05	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
21.05	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
21.05	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
21.05	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
21.05	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
21.05	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
21.05	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
21.05	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
21.05	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
21.05	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
21.05	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
21.05	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
21.05	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
21.05	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
21.05	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
21.05	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
21.05	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
21.05	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
21.05	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
21.05	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
21.05	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
21.05	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
21.05	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
21.05	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
21.05	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
21.05	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
21.05	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
21.05	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
21.05	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
21.05	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
21.05	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.05	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
21.05	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
21.05	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
21.05	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
21.05	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
21.05	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
21.05	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
21.05	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
21.05	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
21.05	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.05	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.05	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.05	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
21.05	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
21.05	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
20.83	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
20.83	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
20.83	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
20.83	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
20.83	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
20.83	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
20.83	Single	7EZC	UKA	7EZC-A_2A-UKA
20.83	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
20.83	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
20.83	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
20.83	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
20.83	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
20.83	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
20.83	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
20.83	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
20.83	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.83	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
20.69	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
20.69	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.69	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
20.69	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.59	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
20.59	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
20.59	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
20.00	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
20.00	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
20.00	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
20.00	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
20.00	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
20.00	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
20.00	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
20.00	Single	6IQL	L745870	6IQL-D₄-L745870
20.00	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
20.00	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
20.00	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
20.00	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
20.00	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
20.00	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
20.00	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
20.00	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
20.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
20.00	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
20.00	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
20.00	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
20.00	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
20.00	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
20.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
20.00	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
20.00	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
20.00	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
20.00	Single	7T32	ZM241385	7T32-A_2A-ZM241385
20.00	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
20.00	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
20.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
20.00	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
20.00	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
20.00	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
20.00	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
20.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
20.00	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
20.00	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
20.00	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
20.00	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
20.00	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
20.00	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
20.00	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
20.00	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
20.00	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
20.00	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
20.00	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
20.00	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
20.00	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
20.00	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
20.00	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
20.00	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
20.00	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
20.00	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
20.00	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
20.00	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
20.00	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
20.00	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
20.00	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
20.00	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
20.00	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
20.00	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
20.00	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
20.00	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
20.00	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
20.00	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
19.44	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
19.44	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
19.35	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
19.35	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
19.35	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
19.35	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
19.23	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
19.23	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
19.23	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
19.23	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
19.23	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
19.23	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
19.05	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
19.05	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
19.05	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
19.05	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
19.05	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
19.05	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
19.05	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
19.05	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
19.05	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
19.05	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
19.05	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
19.05	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
19.05	Single	5UEN	DU172	5UEN-A₁-DU172
19.05	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
19.05	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
19.05	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
19.05	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
19.05	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
19.05	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
19.05	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
19.05	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
19.05	Single	7BU7	BI167107	7BU7-β₁-BI167107
19.05	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
19.05	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
19.05	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
19.05	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
19.05	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
19.05	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
19.05	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
19.05	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
19.05	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
19.05	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
19.05	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
19.05	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
19.05	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
19.05	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
19.05	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
19.05	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
19.05	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
19.05	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
19.05	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
19.05	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
19.05	Consensus	cck_off	Orthosteric Ligand	ccka_off
19.05	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
19.05	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
19.05	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
19.05	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
19.05	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
19.05	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
19.05	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
19.05	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
19.05	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
19.05	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
19.05	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
18.75	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
18.75	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
18.75	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
18.75	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
18.75	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
18.52	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
18.52	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
18.52	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
18.52	Consensus	sst_off	Orthosteric Ligand	sst2_off
18.18	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
18.18	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
18.18	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
18.18	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
18.18	Single	5N2S	PSB36	5N2S-A₁-PSB36
18.18	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
18.18	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
18.18	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
18.18	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
18.18	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
18.18	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
18.18	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
18.18	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
18.18	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
18.18	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
18.18	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
18.18	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
18.18	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
18.18	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
18.18	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
18.18	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
18.18	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
18.18	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
18.18	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
18.18	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
18.18	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.86	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
17.86	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.86	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
17.86	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.65	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
17.65	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
17.65	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
17.65	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
17.50	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
17.39	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
17.39	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
17.39	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
17.39	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
17.39	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
17.39	Single	6E59	L-760735	6E59-NK₁-L-760735
17.39	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
17.39	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
17.39	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
17.39	Single	6OS1	TRV026	6OS1-AT₁-TRV026
17.39	Single	7EPE	NAM563	7EPE-mGlu-NAM563
17.39	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
17.39	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
17.39	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
17.39	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
17.39	Single	7W41	PD176252	7W41-BB₂-PD176252
17.39	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.39	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
17.39	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
17.39	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.39	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.39	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.39	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
17.39	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
17.39	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
17.39	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
17.39	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
17.39	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
17.39	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
17.39	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
17.39	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
17.39	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
17.39	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
17.39	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
17.39	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
17.24	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
17.24	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
17.24	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
17.24	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
17.24	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
17.24	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.24	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
17.24	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
17.14	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
16.67	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
16.67	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
16.67	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
16.67	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
16.67	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
16.67	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
16.67	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
16.67	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
16.67	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
16.67	Single	6OS2	TRV026	6OS2-AT₁-TRV026
16.67	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
16.67	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
16.67	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
16.67	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
16.67	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
16.67	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
16.67	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
16.67	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
16.67	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
16.67	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
16.67	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
16.67	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
16.67	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
16.67	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
16.67	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
16.67	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
16.67	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
16.67	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
16.67	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
16.67	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
16.67	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
16.67	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
16.67	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
16.13	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
16.13	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
16.00	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
16.00	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
16.00	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
16.00	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
16.00	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.00	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
16.00	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
16.00	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
16.00	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.00	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
16.00	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
16.00	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
16.00	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.00	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
15.79	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
15.79	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
15.79	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
15.79	Single	6HLL	CP99994	6HLL-NK₁-CP99994
15.79	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
15.79	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
15.79	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
15.79	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
15.79	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
15.79	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
15.79	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
15.79	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
15.79	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
15.79	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
15.79	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
15.79	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
15.79	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
15.79	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
15.79	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
15.79	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
15.79	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
15.79	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
15.62	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
15.38	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
15.38	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
15.15	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
15.15	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
15.00	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
15.00	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
15.00	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
15.00	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
15.00	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
15.00	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
15.00	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
15.00	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
15.00	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
15.00	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
15.00	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
15.00	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
15.00	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
15.00	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
15.00	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
15.00	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
15.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
15.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
15.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
15.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
15.00	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
15.00	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.00	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
15.00	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
15.00	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
15.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
15.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
15.00	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
15.00	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
15.00	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
15.00	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
15.00	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
15.00	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
15.00	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
15.00	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
15.00	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
14.81	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
14.81	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
14.81	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.81	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
14.71	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
14.71	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
14.29	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
14.29	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
14.29	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
14.29	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
14.29	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
14.29	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
14.29	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
14.29	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
14.29	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
14.29	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
14.29	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
14.29	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
14.29	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
14.29	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
14.29	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
14.29	Single	6TPK	Retosiban	6TPK-OT-Retosiban
14.29	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
14.29	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
14.29	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
14.29	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
14.29	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
14.29	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
14.29	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
14.29	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
14.29	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
14.29	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
14.29	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
14.29	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
14.29	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
14.29	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
14.29	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
14.29	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
14.29	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
14.29	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
14.29	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
14.29	Consensus	sensory_off	Orthosteric Ligand	opsin_off
14.29	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
14.29	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
13.64	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
13.64	Single	3EML	ZM241385	3EML-A_2A-ZM241385
13.64	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
13.64	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
13.64	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
13.64	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
13.64	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
13.64	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
13.64	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
13.64	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
13.64	Single	6D27	CAY10471	6D27-DP₂-CAY10471
13.64	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
13.64	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
13.64	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
13.64	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
13.64	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
13.64	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
13.64	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.64	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
13.64	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
13.64	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
13.64	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
13.64	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
13.64	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
13.64	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
13.64	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
13.64	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
13.64	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
13.64	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
13.64	Consensus	a2_off	Orthosteric Ligand	a2a_off
13.64	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
13.64	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.64	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
13.64	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
13.33	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
13.04	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
13.04	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
13.04	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
13.04	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
13.04	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
13.04	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
13.04	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
13.04	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
13.04	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
13.04	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
13.04	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
13.04	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
13.04	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
13.04	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
13.04	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
13.04	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
13.04	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
13.04	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
12.90	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
12.82	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
12.50	Single	5V56	TC114	5V56-SMO-TC114
12.50	Single	5V57	TC114	5V57-SMO-TC114
12.50	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
12.50	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
12.50	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
12.50	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
12.50	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
12.50	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.50	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
12.50	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
12.50	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
12.20	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
12.12	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
12.12	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
12.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
12.00	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
12.00	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.00	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
12.00	Consensus	nts_on	Orthosteric Ligand	nts1_on
11.76	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
11.76	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
11.76	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
11.76	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
11.76	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
11.76	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
11.76	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
11.76	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
11.76	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
11.54	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
11.54	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
11.54	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
11.54	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
11.11	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
11.11	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
11.11	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
11.11	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
11.11	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
11.11	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
11.11	Consensus	sensory_on	Orthosteric Ligand	opsin_on
10.81	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
10.71	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
10.53	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
10.53	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
10.53	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
10.53	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
10.53	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
10.53	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
10.53	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
10.53	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
10.53	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
10.53	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
10.53	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
10.53	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
10.53	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
10.34	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.00	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
10.00	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
10.00	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
10.00	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
10.00	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
10.00	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
10.00	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
10.00	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
10.00	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
10.00	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
10.00	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
10.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
10.00	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
10.00	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
10.00	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
10.00	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
10.00	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
10.00	Consensus	go_protein	Orthosteric Ligand	go_chemokine
10.00	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
9.52	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
9.52	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
9.52	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
9.52	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
9.52	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
9.52	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
9.52	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
9.52	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
9.52	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
9.52	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
9.52	Consensus	class-f_off	Orthosteric Ligand	smo_off
9.52	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
9.38	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
9.09	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
9.09	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
9.09	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
9.09	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
9.09	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
9.09	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
9.09	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
8.70	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
8.70	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
8.70	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
8.70	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
8.57	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
8.33	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
8.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
8.33	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
8.33	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
8.33	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
8.00	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
8.00	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
8.00	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
8.00	Single	7P2L	4YI	7P2L-mGlu₅-4YI
8.00	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
8.00	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
8.00	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
8.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
7.69	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
7.69	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
7.69	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.69	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
7.69	Consensus	nts_off	Orthosteric Ligand	nts1_off
7.69	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
7.14	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
7.14	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
6.82	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
6.67	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
5.88	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
5.88	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
5.88	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
5.88	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
5.88	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
5.88	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
5.56	Single	6VCB	LSN3160440	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
5.56	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
5.56	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
5.56	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
5.41	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
5.41	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
5.26	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
5.26	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
5.26	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
5.26	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
5.26	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
5.26	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
5.00	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
5.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.00	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
5.00	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
5.00	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
5.00	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
5.00	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
5.00	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
5.00	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
4.76	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
4.76	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
4.76	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.76	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
4.76	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
4.76	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
4.76	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
4.76	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
4.55	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
4.55	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
4.55	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
4.55	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
4.55	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
4.55	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
4.55	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
4.55	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.35	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
4.35	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.35	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
4.35	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
4.35	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
4.35	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.35	Single	8IYX	YL-365	8IYX-GPR34-YL-365
4.35	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
4.35	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.35	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.26	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
4.17	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
4.17	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
3.85	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
3.85	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
3.70	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
3.70	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
3.70	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
3.57	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
3.23	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
2.63	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
2.63	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
2.50	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
2.50	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.17	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3

Consensus Members
	Id	Members
	8GUS	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
	8GUT	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
	8GUQ	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
	8GUR	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
	6KPF	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
	6PT0	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
	6KPG	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
	6N4B	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
	8GHV	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2

Net Summary
I_min	2.84333
Number of Linked Nodes	996
Number of Links	1209
Number of Hubs	194
Number of Links mediated by Hubs	727
Number of Communities	27
Number of Nodes involved in Communities	258
Number of Links involved in Communities	383

Path Summary
Number Of Nodes in MetaPath	140
Number Of Links MetaPath	139
Number of Shortest Paths	2275044
Length Of Smallest Path	3
Average Path Length	33.3115
Length of Longest Path	67
Minimum Path Strength	0.15
Average Path Strength	5.56185
Maximum Path Strength	23.4683
Minimum Path Correlation	0.7
Average Path Correlation	0.977709
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.78571
Average % Of Corr. Nodes	33.4528
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	49.9073
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gi_lipid	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene

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Download gi_cannabinoid.zip

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