psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.30	G.HN.33	4.38065	No	No	0	7	4
2	G.HN.36	b.b5x2	3.4707	No	Yes	0	4	7
3	G.HN.37	b.b5x2	3.25486	No	Yes	0	3	7
4	G.HN.40	b.b5x2	7.31701	No	Yes	0	7	7
5	G.HN.40	b.b5x3	3.31056	No	Yes	0	7	9
6	G.HN.43	b.b5x3	5.60666	No	Yes	0	9	9
7	G.HN.44	b.b5x3	8.49564	No	Yes	0	6	9
8	G.HN.47	b.b4x2	3.33091	No	No	0	6	8
9	G.HN.50	b.b4x2	6.61124	No	No	0	5	8
10	G.HN.51	b.l1x4	3.32758	No	No	0	5	6
11	G.S1.01	G.S3.02	4.43921	No	No	0	6	4
12	G.S1.01	G.S3.04	6.90743	No	Yes	0	6	7
13	G.S1.02	G.S3.03	6.03713	No	Yes	0	5	4
14	G.S1.02	G.h2s4.05	5.66566	No	No	0	5	9
15	G.S1.03	G.S3.06	4.46137	No	Yes	0	9	7
16	G.S1.04	G.S3.03	3.1747	No	Yes	0	7	4
17	G.S1.04	G.S3.05	2.82857	No	Yes	0	7	6
18	G.S1.04	G.S4.03	3.70068	No	No	0	7	8
19	G.S1.05	G.S1.07	4.33741	No	No	0	9	9
20	G.S1.05	G.h2s4.01	12.9005	No	Yes	0	9	7
21	G.S1.05	G.S4.02	4.49576	No	No	0	9	8
22	G.H1.01	G.S1.06	5.02095	No	Yes	20	9	8
23	G.S1.06	G.S3.05	5.80384	Yes	Yes	0	8	6
24	G.S1.06	G.S3.07	3.63011	Yes	No	20	8	5
25	G.S1.06	G.S4.03	2.92518	Yes	No	0	8	8
26	G.H3.12	G.S1.07	3.41711	No	No	0	7	9
27	G.H3.01	G.s1h1.04	5.40407	Yes	No	0	9	9
28	G.S4.05	G.s1h1.05	2.88192	No	No	0	9	9
29	G.H1.01	G.S3.07	6.90773	No	No	20	9	5
30	G.H1.04	G.S4.05	3.61371	No	No	9	9	9
31	G.H1.04	G.S5.05	3.66666	No	Yes	9	9	9
32	G.H1.04	G.S5.07	3.25453	No	Yes	9	9	8
33	G.H1.05	G.S2.04	3.08685	No	No	0	7	9
34	G.H1.07	G.H5.03	2.89811	No	Yes	0	9	4
35	G.H1.08	G.S2.06	4.46715	No	Yes	0	9	3
36	G.hfs2.07	b.l7x4	3.27748	No	Yes	0	7	9
37	G.S2.01	b.l5x5	4.38464	No	Yes	2	9	9
38	G.S2.01	b.l7x2	2.85156	No	No	2	9	9
39	G.S2.02	G.S3.07	2.88796	No	No	0	9	5
40	G.S2.03	G.S3.04	7.14772	No	Yes	2	5	7
41	G.S2.03	G.S3.06	8.00497	No	Yes	2	5	7
42	G.S2.04	G.S3.05	2.92429	No	Yes	0	9	6
43	G.S2.05	G.S3.04	10.37	No	Yes	2	6	7
44	G.S2.06	G.S3.03	11.7653	Yes	Yes	0	3	4
45	G.S2.06	G.S3.05	3.18243	Yes	Yes	0	3	6
46	G.H5.04	G.S2.06	2.92048	No	Yes	0	8	3
47	G.S2.07	G.S3.02	7.38653	No	No	0	9	4
48	G.S2.08	G.s2s3.01	5.7026	Yes	No	8	3	5
49	G.H5.04	G.S2.08	4.38594	No	Yes	0	8	3
50	G.H5.05	G.S2.08	4.20747	No	Yes	8	7	3
51	G.H5.08	G.S2.08	7.16075	Yes	Yes	8	8	3
52	G.H5.05	G.s2s3.01	4.7548	No	No	8	7	5
53	G.H5.08	G.s2s3.01	7.30814	Yes	No	8	8	5
54	G.S3.01	G.S3.03	5.77407	No	Yes	8	3	4
55	G.H5.08	G.S3.01	3.20291	Yes	No	8	8	3
56	G.S3.01	I2x51	4.34822	No	Yes	8	3	6
57	G.H5.08	G.S3.03	3.00628	Yes	Yes	8	8	4
58	G.H5.11	G.S3.03	3.89118	No	Yes	0	6	4
59	G.S3.04	G.S3.06	6.04103	Yes	Yes	2	7	7
60	G.S3.06	G.h2s4.01	3.60827	Yes	Yes	2	7	7
61	G.S3.06	b.l5x5	14.3167	Yes	Yes	2	7	9
62	G.H2.07	G.S3.08	8.70984	Yes	No	0	9	9
63	G.H2.07	G.s3h2.03	6.00272	Yes	No	2	9	9
64	G.s3h2.03	b.l7x4	4.21575	No	Yes	0	9	9
65	G.s3h2.03	b.l9x6	5.68685	No	Yes	2	9	8
66	G.H2.03	G.H2.05	6.79761	No	No	2	8	9
67	G.H2.03	b.l13x6	3.72742	No	Yes	2	8	9
68	G.H2.04	G.H2.07	5.57775	No	Yes	0	9	9
69	G.H2.04	G.H3.08	4.28399	No	No	0	9	5
70	G.H2.06	b.l9x6	3.04093	Yes	Yes	2	8	8
71	G.H2.06	b.b14x1	8.473	Yes	No	2	8	8
72	G.H2.06	b.l15x1	4.02171	Yes	Yes	2	8	7
73	G.H2.06	b.l17x6	8.35968	Yes	Yes	2	8	9
74	G.H2.06	b.b18x1	4.4774	Yes	No	2	8	9
75	G.H2.06	b.l19x1	2.97465	Yes	Yes	2	8	9
76	G.H2.07	G.h2s4.01	3.1843	Yes	Yes	2	9	7
77	G.H2.07	b.l9x6	4.94486	Yes	Yes	2	9	8
78	G.H2.08	G.H3.18	4.17181	No	Yes	0	9	5
79	G.H2.09	G.H3.17	8.23643	No	Yes	2	8	4
80	G.H2.09	b.b2x1	3.16388	No	Yes	2	8	8
81	G.H2.09	b.l27x1	3.05694	No	Yes	2	8	9
82	G.H2.10	b.b2x1	4.10197	No	Yes	2	8	8
83	G.H2.10	b.l3x1	3.5003	No	Yes	2	8	9
84	G.h2s4.01	b.l5x5	10.779	Yes	Yes	2	7	9
85	G.H3.17	G.h2s4.02	3.85156	Yes	No	2	4	9
86	G.h2s4.02	b.l1x6	6.37775	No	Yes	2	9	9
87	G.H3.18	G.S4.02	4.9601	Yes	No	19	5	8
88	G.S4.02	G.h3s5.03	3.94183	No	No	19	8	4
89	G.H5.07	G.S4.03	2.92381	No	No	0	3	8
90	G.S4.04	G.S4.06	2.87629	No	No	0	7	7
91	G.H3.08	G.S4.04	5.01968	No	No	0	5	7
92	G.H3.09	G.S4.04	9.09502	Yes	No	0	9	7
93	G.S4.05	G.S5.07	3.26027	No	Yes	9	9	8
94	G.H3.05	G.S4.06	2.94931	No	No	0	9	7
95	G.H4.15	G.S4.06	6.59449	Yes	No	0	5	7
96	G.S4.07	G.s4h3.03	3.66607	No	No	0	7	9
97	G.S4.07	G.s5hg.01	5.66772	No	No	0	7	9
98	G.S5.06	G.s4h3.01	5.02267	No	No	0	9	8
99	G.HG.04	G.s4h3.01	6.33617	No	No	0	6	8
100	G.HG.03	G.s4h3.02	4.06408	Yes	No	0	9	7
101	G.H3.01	G.s4h3.03	7.25438	Yes	No	0	9	9
102	G.s4h3.04	G.s4h3.05	4.60624	Yes	No	21	8	8
103	G.HG.04	G.s4h3.04	2.92964	No	Yes	0	6	8
104	G.HG.07	G.s4h3.04	5.851	No	Yes	21	5	8
105	G.HG.13	G.s4h3.04	2.87717	No	Yes	0	1	8
106	G.HG.15	G.s4h3.04	5.15008	No	Yes	0	5	8
107	G.hgh4.01	G.s4h3.04	3.70084	Yes	Yes	0	3	8
108	G.HG.07	G.s4h3.05	2.99089	No	No	21	5	8
109	G.H3.01	G.s4h3.06	2.8313	Yes	No	0	9	9
110	G.H3.03	G.s4h3.15	3.98698	Yes	No	0	8	6
111	G.H3.02	G.hgh4.02	3.46179	No	Yes	0	9	6
112	G.H3.06	G.H4.14	3.82803	Yes	Yes	0	9	3
113	G.H3.06	G.H4.15	7.24235	Yes	Yes	0	9	5
114	G.H3.06	G.h4s6.01	3.58576	Yes	No	0	9	4
115	G.H3.09	G.H3.13	4.41909	Yes	Yes	6	9	8
116	G.H3.09	G.S5.02	4.27578	Yes	No	6	9	7
117	G.H3.09	G.S5.04	3.23949	Yes	Yes	6	9	8
118	G.H3.09	G.H4.15	5.61206	Yes	Yes	6	9	5
119	G.H3.09	G.h4s6.01	4.14047	Yes	No	0	9	4
120	G.H3.09	G.S6.01	3.03582	Yes	No	0	9	4
121	G.H3.10	G.H3.14	4.50722	No	Yes	0	9	5
122	G.H3.10	G.h4s6.01	6.34567	No	No	0	9	4
123	G.H3.13	G.H3.14	3.12433	Yes	Yes	0	8	5
124	G.H3.13	G.S5.02	3.62221	Yes	No	6	8	7
125	G.H3.13	G.h4s6.02	4.64493	Yes	No	0	8	4
126	G.H3.14	G.h4s6.03	4.49627	Yes	No	0	5	8
127	G.H3.15	G.H3.17	3.78754	No	Yes	0	8	4
128	G.H3.15	G.H3.18	6.86103	No	Yes	0	8	5
129	G.H3.16	G.H3.17	11.4844	No	Yes	0	8	4
130	G.H3.17	b.l25x6	8.49856	Yes	Yes	2	4	8
131	G.H3.17	b.l27x1	3.1948	Yes	Yes	2	4	9
132	G.H3.18	G.h3s5.03	4.1748	Yes	No	19	5	4
133	G.H5.14	G.S5.01	7.94471	No	No	0	8	7
134	G.S5.03	G.S5.05	3.23382	No	Yes	0	6	9
135	G.H5.10	G.S5.03	6.13654	No	No	0	4	6
136	G.S5.04	G.S5.06	3.80545	Yes	No	0	8	9
137	G.H4.15	G.S5.04	5.50865	Yes	Yes	6	5	8
138	G.S5.04	G.S6.03	2.78739	Yes	No	6	8	7
139	G.S5.05	G.S6.04	4.19045	Yes	No	0	9	5
140	G.S5.05	G.s6h5.01	5.02056	Yes	Yes	9	9	4
141	G.H5.03	G.S5.05	4.20092	Yes	Yes	9	4	9
142	G.H5.07	G.S5.05	3.05281	No	Yes	0	3	9
143	G.S5.06	G.S6.05	5.77649	No	Yes	0	9	9
144	G.S5.07	G.s5hg.01	3.65849	Yes	No	0	8	9
145	G.S5.07	G.s6h5.01	5.21452	Yes	Yes	9	8	4
146	G.HG.03	G.s5hg.01	4.09607	Yes	No	0	9	9
147	G.HG.01	G.S6.05	5.9573	Yes	Yes	6	9	9
148	G.HG.04	G.HG.08	3.28847	No	No	0	6	9
149	G.H4.03	G.HG.05	4.84967	No	No	0	5	9
150	G.HG.15	G.hgh4.05	7.7627	No	Yes	0	5	6
151	G.hgh4.01	G.hgh4.02	4.27068	Yes	Yes	0	3	6
152	G.H4.10	G.hgh4.02	5.31509	Yes	Yes	22	3	6
153	G.H4.14	G.hgh4.02	5.27237	Yes	Yes	22	3	6
154	G.H4.05	G.hgh4.05	8.91591	Yes	Yes	0	4	6
155	G.H4.10	G.hgh4.05	14.3566	Yes	Yes	0	3	6
156	G.H4.05	G.hgh4.08	4.96217	Yes	No	0	4	7
157	G.H4.07	G.S6.05	7.82653	No	Yes	6	7	9
158	G.H4.10	G.H4.14	8.85222	Yes	Yes	22	3	3
159	G.H4.12	G.H4.16	5.01204	Yes	Yes	6	7	8
160	G.H4.12	G.S6.03	8.63289	Yes	No	6	7	7
161	G.H4.12	G.S6.05	4.8597	Yes	Yes	6	7	9
162	G.H4.16	G.S6.03	3.98227	Yes	No	6	8	7
163	G.S6.01	G.h4s6.02	4.51985	No	No	0	4	4
164	G.S6.02	G.h4s6.12	3.80742	Yes	No	0	5	7
165	G.H5.10	G.S6.02	7.98325	No	Yes	0	4	5
166	G.H5.13	G.S6.02	6.71061	Yes	Yes	11	6	5
167	G.H5.14	G.S6.02	5.54751	No	Yes	0	8	5
168	G.H5.17	G.S6.02	4.08213	Yes	Yes	11	6	5
169	G.H5.06	G.S6.04	14.7355	No	No	0	5	5
170	G.H5.03	G.s6h5.01	7.14682	Yes	Yes	9	4	4
171	G.H5.05	G.H5.09	4.75719	No	No	0	7	8
172	G.H5.08	G.H5.12	3.51344	Yes	No	8	8	8
173	G.H5.08	I2x51	3.424	Yes	Yes	8	8	6
174	G.H5.12	I2x50	2.86453	No	No	0	8	8
175	G.H5.12	I2x51	2.77168	No	Yes	8	8	6
176	G.H5.13	G.H5.17	3.93769	Yes	Yes	11	6	6
177	5x68	G.H5.13	4.99547	No	Yes	11	7	6
178	G.H5.15	G.H5.19	3.37832	No	No	0	7	4
179	G.H5.16	I2x50	3.37908	No	No	0	7	8
180	5x68	G.H5.16	4.90834	No	No	0	7	7
181	5x68	G.H5.17	5.24077	No	Yes	11	7	6
182	3x53	G.H5.19	3.71424	No	No	1	8	4
183	G.H5.19	I2x53	3.0592	No	Yes	1	4	8
184	G.H5.20	G.H5.25	3.5189	Yes	Yes	0	8	8
185	G.H5.20	G.H5.26	3.56543	Yes	Yes	0	8	7
186	3x54	G.H5.20	4.49823	No	Yes	0	9	8
187	3x50	G.H5.23	9.22978	Yes	No	0	9	4
188	6x37	G.H5.25	3.30536	No	Yes	0	8	8
189	6x29	G.H5.26	5.08659	No	Yes	0	7	7
190	b.1x4	g.h1x4	3.13798	No	No	0	8	5
191	b.1x7	g.h1x8	4.15789	No	Yes	0	8	7
192	b.1x11	g.h1x11	4.70659	No	No	0	8	9
193	b.1x11	g.h1x12	3.15694	No	No	0	8	6
194	b.1x13	b.1x16	3.61127	No	No	0	1	4
195	b.1x15	b.1x19	4.13042	No	No	0	7	6
196	b.1x19	b.b21x1	8.37266	No	Yes	0	6	7
197	b.1x19	b.b21x2	4.31393	No	No	0	6	6
198	b.b21x2	b.lh12x1	3.58483	No	No	0	6	3
199	b.lh12x2	g.l1x6	6.81782	No	No	0	8	4
200	b.lh12x2	g.h2x2	6.26631	No	No	0	8	9
201	b.h2x2	b.lh12x4	3.91066	No	No	0	1	3
202	b.h2x3	b.lh12x4	6.04823	No	No	0	1	3
203	b.b21x4	b.h2x1	2.94017	No	Yes	0	5	5
204	b.b21x5	b.h2x1	5.90838	Yes	Yes	0	4	5
205	b.h2x5	b.lhb1x3	2.84238	No	Yes	0	5	2
206	b.h2x5	b.l24x2	3.84547	No	No	0	5	6
207	b.l22x5	b.lhb1x3	3.44051	Yes	Yes	0	9	2
208	b.l24x3	b.lhb1x3	2.86025	Yes	Yes	0	5	2
209	b.lhb1x3	g.h2x9	2.92258	Yes	No	0	2	4
210	b.lhb1x4	b.lhb1x5	3.11975	No	No	0	1	1
211	b.l22x5	b.lhb1x6	5.17761	Yes	Yes	14	9	3
212	b.b24x7	b.lhb1x6	6.63059	No	Yes	14	9	3
213	b.lhb1x10	b.lhb1x8	5.11313	No	No	0	4	2
214	b.b23x1	b.lhb1x9	2.79352	Yes	No	0	5	3
215	b.b25x7	b.lhb1x11	5.25028	No	No	0	7	4
216	b.lhb1x11	g.ctx5	3.55855	No	No	0	4	9
217	b.b1x1	b.b1x3	4.53906	No	No	0	5	7
218	b.b1x2	b.b28x4	7.30703	No	Yes	12	3	6
219	b.b1x2	b.b28x6	8.6636	No	Yes	12	3	9
220	b.b1x3	b.b28x7	6.94615	No	No	0	7	9
221	b.b1x4	b.b5x1	3.66014	No	No	0	7	5
222	b.b1x4	b.b28x5	3.72015	No	No	7	7	5
223	b.b1x4	g.ctx16	5.48311	No	Yes	7	7	8
224	b.b1x5	b.l1x1	7.8329	No	No	0	3	7
225	b.b1x5	b.b28x4	7.2327	No	Yes	0	3	6
226	b.b1x6	b.b4x6	18.3527	No	Yes	0	9	9
227	b.b1x6	b.b5x1	3.18559	No	No	0	9	5
228	b.b1x6	b.b28x3	5.86778	No	Yes	0	9	7
229	b.b28x2	b.l1x1	6.33098	No	No	0	4	7
230	b.l1x3	b.l1x7	8.87237	Yes	No	0	9	9
231	b.b3x4	b.l1x3	7.32824	No	Yes	5	9	9
232	b.b3x6	b.l1x3	11.9884	No	Yes	5	9	9
233	b.l1x3	b.l3x2	3.58614	Yes	Yes	5	9	9
234	b.b4x4	b.l1x3	11.4445	No	Yes	5	8	9
235	b.b4x6	b.l1x3	3.53028	Yes	Yes	5	9	9
236	b.l1x4	b.l3x2	5.83831	No	Yes	0	6	9
237	b.l1x5	b.l3x2	2.88727	No	Yes	0	7	9
238	b.b2x1	b.l1x6	4.82982	Yes	Yes	2	8	9
239	b.l1x6	b.l3x1	5.14253	Yes	Yes	2	9	9
240	b.l1x6	b.l27x1	21.475	Yes	Yes	2	9	9
241	b.b28x3	b.l1x7	3.06117	Yes	No	0	7	9
242	b.b2x1	b.l3x1	13.284	Yes	Yes	2	8	9
243	b.b2x1	b.l27x1	6.22498	Yes	Yes	2	8	9
244	b.b2x3	b.b2x5	3.77271	No	Yes	5	6	7
245	b.b2x3	b.b3x2	3.13137	No	No	5	6	5
246	b.b26x2	b.b2x3	5.124	No	No	0	7	6
247	b.b10x4	b.b2x4	12.8665	No	No	0	6	6
248	b.b2x5	b.b3x2	10.0361	Yes	No	5	7	5
249	b.b2x5	b.l4x1	4.7967	Yes	No	0	7	5
250	b.b2x5	b.l26x1	10.7124	Yes	No	5	7	7
251	b.b27x2	b.b2x5	4.2191	No	Yes	0	5	7
252	b.b6x5	b.l2x1	4.69576	Yes	No	0	6	5
253	b.l2x3	b.l2x5	3.45437	No	No	0	8	5
254	b.b3x1	b.l2x3	5.48943	No	No	0	5	8
255	b.l26x1	b.l2x4	6.54361	No	No	5	7	5
256	b.l26x3	b.l2x4	9.60413	No	No	5	7	5
257	b.b4x7	b.l2x5	14.8306	No	No	0	8	5
258	b.l2x5	b.l4x2	23.3584	No	Yes	0	5	4
259	b.b3x1	b.b6x5	3.75763	No	Yes	0	5	6
260	b.b3x2	b.b4x6	4.45558	No	Yes	5	5	9
261	b.b3x3	b.b4x3	3.09336	Yes	Yes	10	8	7
262	b.b3x3	b.b4x5	3.60879	Yes	No	0	8	7
263	b.b3x3	b.b6x3	3.00514	Yes	No	0	8	8
264	b.b3x3	b.b6x5	4.80087	Yes	Yes	10	8	6
265	b.b3x3	b.b7x2	2.83062	Yes	No	10	8	8
266	b.b3x4	b.b4x6	5.67737	No	Yes	5	9	9
267	b.b28x3	b.b3x4	4.13457	Yes	No	0	7	9
268	b.b3x5	b.l5x6	3.01683	No	No	0	9	9
269	b.b3x5	b.b6x3	2.99471	No	No	0	9	8
270	b.b3x6	b.l3x2	7.76513	No	Yes	5	9	9
271	b.l3x1	b.l5x5	5.63259	Yes	Yes	2	9	9
272	b.b4x2	b.l3x2	5.65005	No	Yes	0	8	9
273	b.b4x1	b.l5x1	3.4671	No	Yes	0	8	8
274	b.b4x3	b.b5x7	4.15971	Yes	Yes	0	7	7
275	b.b4x3	b.l5x1	4.91423	Yes	Yes	10	7	8
276	b.b4x3	b.b7x4	4.11051	Yes	No	10	7	8
277	b.b4x4	b.b4x6	13.0534	No	Yes	5	8	9
278	b.b4x4	b.b5x3	4.29966	No	Yes	5	8	9
279	b.b4x5	b.b5x5	6.8071	No	Yes	0	7	5
280	b.b4x5	b.l8x1	3.13912	No	No	0	7	5
281	b.b4x6	b.b5x3	10.3078	Yes	Yes	5	9	9
282	b.b4x7	b.l4x3	7.90215	No	No	0	8	6
283	b.l4x1	g.ctx16	4.61717	No	Yes	0	5	8
284	b.l4x2	g.ctx15	11.5477	Yes	Yes	7	4	9
285	b.l4x2	g.ctx16	6.78881	Yes	Yes	7	4	8
286	b.b5x2	b.l4x3	9.49501	Yes	No	0	7	6
287	b.b5x4	b.b5x5	6.11692	No	Yes	0	5	5
288	b.b5x5	b.l8x8	4.7501	Yes	No	0	5	4
289	b.b5x7	b.b5x8	3.37426	Yes	No	0	7	5
290	b.b5x7	b.b8x4	6.48116	Yes	Yes	0	7	6
291	b.b5x7	b.l8x8	7.98426	Yes	No	0	7	4
292	b.l5x1	b.l5x6	3.60681	Yes	No	0	8	9
293	b.b7x4	b.l5x1	3.71878	No	Yes	10	8	8
294	b.b8x4	b.l5x1	5.03903	Yes	Yes	10	6	8
295	b.b9x3	b.l5x2	5.34703	No	No	0	6	6
296	b.l5x3	b.l7x3	8.50339	No	No	0	8	9
297	b.l5x4	b.l5x5	4.39546	No	Yes	0	8	9
298	b.l5x5	b.l7x2	5.38404	Yes	No	2	9	9
299	b.b6x1	b.l7x1	3.40208	No	No	0	9	9
300	b.b6x1	b.l9x6	4.64224	No	Yes	0	9	8
301	b.b10x3	b.b6x2	4.18627	No	No	0	8	8
302	b.b6x5	b.l6x4	4.22536	Yes	No	0	6	5
303	b.b6x5	b.b7x2	3.04009	Yes	No	10	6	8
304	b.b10x5	b.l6x1	5.78576	Yes	No	0	9	6
305	b.l6x3	b.l6x5	7.90562	No	Yes	16	6	4
306	b.l10x3	b.l6x3	8.06654	No	No	16	6	6
307	b.b7x1	b.l6x5	3.84963	Yes	Yes	16	4	4
308	b.l6x5	b.l8x2	7.39629	Yes	No	0	4	4
309	b.l10x3	b.l6x5	4.32634	No	Yes	16	6	4
310	b.b7x1	b.b8x3	3.36858	Yes	Yes	0	4	6
311	b.b7x1	b.b8x5	10.2652	Yes	No	0	4	4
312	b.b7x1	b.l10x3	6.89928	Yes	No	16	4	6
313	b.b7x2	b.l8x1	4.34457	No	No	0	8	5
314	b.b10x5	b.b7x3	3.4529	Yes	No	0	9	9
315	b.b7x4	b.b8x4	3.19091	No	Yes	10	8	6
316	b.l7x2	b.l9x6	2.84063	No	Yes	2	9	8
317	b.l7x3	b.l7x5	5.47016	No	No	0	9	6
318	b.l7x4	b.l9x5	3.95707	Yes	No	0	9	8
319	b.b9x3	b.l7x5	3.78774	No	No	0	6	6
320	b.b8x1	b.b9x4	3.90461	No	No	0	8	9
321	b.b8x2	b.b8x4	5.29141	No	Yes	0	8	6
322	b.b8x2	b.b9x3	3.49416	No	No	0	8	6
323	b.b8x3	b.b9x4	2.79542	Yes	No	0	6	9
324	b.b10x5	b.b8x3	3.01498	Yes	Yes	0	9	6
325	b.b8x3	b.l12x1	4.31158	Yes	Yes	0	6	6
326	b.b8x4	b.l8x10	6.17428	Yes	No	0	6	4
327	b.b8x5	b.l8x3	5.07053	No	No	0	4	3
328	b.l8x1	b.l8x8	2.96011	No	No	0	5	4
329	b.l8x3	b.l8x9	2.78473	No	No	0	3	3
330	b.l8x5	b.l8x7	3.19108	No	No	0	3	3
331	b.l8x5	b.l8x9	3.96385	No	No	0	3	3
332	b.b12x6	b.b9x4	15.6076	Yes	No	0	8	9
333	b.l9x3	b.l9x7	3.44421	Yes	No	2	9	7
334	b.b11x4	b.l9x3	6.23961	Yes	Yes	2	9	9
335	b.b11x6	b.l9x3	14.8084	No	Yes	2	9	9
336	b.l11x2	b.l9x3	6.62003	Yes	Yes	2	9	9
337	b.b12x4	b.l9x3	2.90731	No	Yes	2	4	9
338	b.b12x6	b.l9x3	5.59509	Yes	Yes	2	8	9
339	b.l11x2	b.l9x4	8.25903	Yes	No	0	9	5
340	b.l11x1	b.l9x6	5.28652	No	Yes	2	9	8
341	b.l13x6	b.l9x6	7.01927	Yes	Yes	2	9	8
342	b.b14x1	b.l9x6	3.42072	No	Yes	2	8	8
343	b.b11x4	b.l9x7	3.37598	Yes	No	2	9	7
344	b.b10x1	b.b11x5	3.10907	No	No	0	9	6
345	b.b10x2	b.b10x4	3.85096	No	No	0	6	6
346	b.b10x2	b.b14x3	4.5305	No	Yes	0	6	5
347	b.b10x4	b.b14x5	3.41011	No	No	0	6	5
348	b.b10x5	b.b11x2	8.40414	Yes	No	0	9	7
349	b.b11x1	b.l10x1	4.71604	No	No	0	5	3
350	b.b14x5	b.l10x1	4.66548	No	No	0	5	3
351	b.l10x1	b.l14x4	3.27832	No	No	0	3	1
352	b.b11x1	b.l10x2	7.16202	No	No	0	5	5
353	b.b12x7	b.l10x4	6.72298	No	No	24	9	3
354	b.l10x4	b.l12x2	6.19838	No	No	24	3	6
355	b.b11x1	b.b12x5	4.20614	No	No	0	5	6
356	b.b11x2	b.b12x6	2.83815	No	Yes	0	7	8
357	b.b11x2	b.l12x1	3.6078	No	Yes	0	7	6
358	b.b11x3	b.b14x3	3.56761	No	Yes	4	5	5
359	b.b11x3	b.b15x1	4.02244	No	Yes	4	5	9
360	b.b11x4	b.b12x6	9.27261	Yes	Yes	2	9	8
361	b.b11x5	b.l13x7	5.36877	No	Yes	0	6	9
362	b.b11x5	b.b14x3	5.35632	No	Yes	0	6	5
363	b.b11x6	b.l11x1	3.22657	No	No	2	9	9
364	b.b11x6	b.l11x2	7.87866	No	Yes	2	9	9
365	b.l11x1	b.l13x6	4.61357	No	Yes	2	9	9
366	b.b12x2	b.l11x2	8.8522	No	Yes	0	7	9
367	b.b12x2	b.l13x1	2.79438	No	No	0	7	2
368	b.b12x3	b.b13x7	4.05154	No	Yes	0	8	7
369	b.b12x3	b.l13x7	3.43184	No	Yes	0	8	9
370	b.b12x4	b.b13x3	4.82902	No	No	2	4	4
371	b.b12x5	b.b13x4	3.3726	No	No	4	6	4
372	b.b12x5	b.b13x5	3.60362	No	No	4	6	4
373	b.b12x6	b.b13x3	13.6277	Yes	No	2	8	4
374	b.b12x7	b.l12x2	3.17642	No	No	24	9	6
375	b.b12x7	b.l12x3	8.88593	No	No	0	9	5
376	b.b13x2	b.l12x3	4.87598	No	No	0	4	5
377	b.b13x3	b.b13x6	5.09891	No	No	0	4	4
378	b.b13x4	b.b13x5	3.30172	No	No	4	4	4
379	b.b13x5	b.b13x7	5.81231	No	Yes	4	4	7
380	b.b13x7	b.b15x1	10.0847	Yes	Yes	4	7	9
381	b.b13x7	b.b16x6	14.3438	Yes	Yes	4	7	8
382	b.b13x7	b.b17x1	3.67492	Yes	No	0	7	4
383	b.l13x3	b.l13x7	5.5723	Yes	Yes	4	9	9
384	b.b15x3	b.l13x3	5.22528	No	Yes	4	9	9
385	b.b15x5	b.l13x3	7.83571	No	Yes	4	8	9
386	b.l13x3	b.l15x2	5.50721	Yes	Yes	4	9	9
387	b.b16x4	b.l13x3	14.5275	Yes	Yes	4	6	9
388	b.b16x6	b.l13x3	3.60106	Yes	Yes	4	8	9
389	b.l13x4	b.l15x2	7.05794	No	Yes	0	3	9
390	b.l13x6	b.l15x1	3.45843	Yes	Yes	2	9	7
391	b.b15x3	b.l13x7	2.85289	No	Yes	4	9	9
392	b.b14x1	b.l15x1	2.953	No	Yes	2	8	7
393	b.b14x2	b.b18x3	4.94394	No	Yes	0	7	8
394	b.b14x3	b.b15x1	3.95279	Yes	Yes	4	5	9
395	b.b14x4	b.b18x5	5.40518	No	Yes	0	8	5
396	b.b18x5	b.l14x1	4.3764	Yes	No	0	5	4
397	b.l14x2	b.l18x4	3.2444	No	No	0	4	7
398	b.l14x3	b.l14x5	8.37432	No	No	0	5	5
399	b.l14x5	b.l16x2	7.24075	No	No	0	5	9
400	b.b16x5	b.l14x6	4.70414	No	No	0	5	3
401	b.b16x7	b.l14x6	3.27946	No	No	0	9	3
402	b.b15x1	b.b16x6	11.8092	Yes	Yes	4	9	8
403	b.b15x2	b.b18x3	5.7164	No	Yes	3	6	8
404	b.b15x2	b.b18x5	7.542	No	Yes	0	6	5
405	b.b15x2	b.b19x2	7.89548	No	Yes	3	6	6
406	b.b15x3	b.b16x6	6.21391	No	Yes	4	9	8
407	b.b15x4	b.l17x7	3.25965	No	No	0	6	7
408	b.b15x5	b.l15x2	3.33515	No	Yes	4	8	9
409	b.l15x1	b.l17x6	9.23273	Yes	Yes	2	7	9
410	b.b16x2	b.l15x2	8.00259	No	Yes	0	5	9
411	b.b16x4	b.b16x6	7.93812	Yes	Yes	4	6	8
412	b.b16x4	b.b17x3	6.37918	Yes	No	4	6	5
413	b.b16x4	b.b17x6	11.441	Yes	No	0	6	7
414	b.b16x5	b.b17x5	4.45113	No	Yes	0	5	7
415	b.b16x5	b.l20x1	5.9526	No	No	0	5	6
416	b.b16x6	b.b17x3	5.31484	Yes	No	4	8	5
417	b.b16x7	b.l16x3	9.24031	No	No	17	9	3
418	b.b16x7	b.b17x4	9.71462	No	No	17	9	5
419	b.b17x2	b.l16x3	5.89861	No	No	17	3	3
420	b.b17x4	b.l16x3	3.41119	No	No	17	5	3
421	b.b17x2	b.b17x4	2.92009	No	No	17	3	5
422	b.b17x3	g.h1x10	4.19462	No	No	0	5	9
423	b.b17x5	b.b17x7	7.64174	Yes	Yes	3	7	8
424	b.b17x5	b.b21x1	10.7922	Yes	Yes	3	7	7
425	b.b17x5	g.l1x2	3.53771	Yes	No	0	7	2
426	b.b17x6	g.h1x14	6.59263	No	No	0	7	9
427	b.b17x7	b.b19x2	9.66439	Yes	Yes	3	8	6
428	b.b17x7	b.b20x6	9.223	Yes	Yes	3	8	6
429	b.b17x7	b.b21x1	4.14979	Yes	Yes	3	8	7
430	b.l17x3	b.l17x7	7.57095	Yes	No	3	9	7
431	b.b19x4	b.l17x3	7.52652	Yes	Yes	3	8	9
432	b.b19x6	b.l17x3	13.0307	No	Yes	3	9	9
433	b.b20x4	b.l17x3	17.0238	Yes	Yes	3	8	9
434	b.l17x4	b.l19x2	6.16173	No	Yes	0	3	9
435	b.l17x5	b.l19x1	3.45596	No	Yes	0	6	9
436	b.l17x5	b.l19x2	4.24668	No	Yes	0	6	9
437	b.l17x6	b.l19x1	5.48031	Yes	Yes	2	9	9
438	b.b19x4	b.l17x7	4.67881	Yes	No	3	8	7
439	b.b18x1	b.l19x1	8.8113	No	Yes	2	9	9
440	b.b18x2	b.b22x3	3.13293	No	No	0	5	6
441	b.b18x3	b.b19x2	5.25826	Yes	Yes	3	8	6
442	b.b18x3	b.b19x4	4.50488	Yes	Yes	3	8	8
443	b.l18x1	b.l18x2	10.2417	Yes	Yes	13	6	7
444	b.l18x1	b.l18x3	5.38438	Yes	No	13	6	5
445	b.b22x5	b.l18x1	8.89258	Yes	Yes	13	7	6
446	b.l18x1	b.l22x4	4.00845	Yes	No	13	6	9
447	b.l18x1	g.h2x8	6.29039	Yes	No	0	6	7
448	b.l18x1	g.h2x11	4.23498	Yes	Yes	13	6	6
449	b.b22x5	b.l18x2	3.86189	Yes	Yes	13	7	7
450	b.l18x2	b.l22x4	3.19662	Yes	No	13	7	9
451	b.l18x2	g.h2x11	4.64202	Yes	Yes	13	7	6
452	b.l18x3	b.l18x5	7.7017	No	No	0	5	2
453	b.l18x3	g.h2x11	11.3046	No	Yes	13	5	6
454	b.l18x5	b.l20x2	9.92482	No	Yes	0	2	9
455	b.b19x2	b.b20x6	11.0164	Yes	Yes	3	6	6
456	b.b19x2	b.l20x1	2.78401	Yes	No	0	6	6
457	b.b19x3	b.b22x5	3.08396	No	Yes	0	4	7
458	b.b19x4	b.b20x6	6.39529	Yes	Yes	3	8	6
459	b.b19x5	b.l21x9	4.69604	No	No	0	5	6
460	b.b19x6	b.l19x2	6.69126	No	Yes	3	9	9
461	b.b20x2	b.l19x2	8.50026	No	Yes	0	6	9
462	b.b20x2	b.b20x4	6.42191	No	Yes	0	6	8
463	b.b20x2	b.l21x1	4.12432	No	No	0	6	2
464	b.b20x3	b.b21x7	4.013	No	Yes	0	8	5
465	b.b20x3	b.l21x9	4.3734	No	No	0	8	6
466	b.b20x4	b.b20x6	3.72159	Yes	Yes	3	8	6
467	b.b20x4	b.b21x3	13.8685	Yes	No	3	8	6
468	b.b20x4	b.b21x6	8.03781	Yes	No	3	8	1
469	b.b20x5	b.b21x4	4.00774	No	No	0	7	5
470	b.b20x5	b.b21x7	5.26698	No	Yes	0	7	5
471	b.b20x6	b.b21x3	5.95761	Yes	No	3	6	6
472	b.b20x7	b.l20x2	3.39483	Yes	Yes	0	9	9
473	b.b20x7	b.l20x3	4.24322	Yes	No	0	9	7
474	b.b20x7	b.b21x4	6.07388	Yes	No	0	9	5
475	b.b20x7	g.h2x4	4.29473	Yes	No	0	9	7
476	b.l20x2	g.l1x5	6.90568	Yes	No	0	9	4
477	b.l20x2	g.h2x7	6.38584	Yes	No	0	9	5
478	b.b21x1	g.l1x4	9.63304	Yes	Yes	0	7	8
479	b.b21x2	g.h2x1	3.40309	No	No	0	6	8
480	b.b21x3	b.b21x6	3.68408	No	No	3	6	1
481	b.b21x5	b.b21x7	7.73708	Yes	Yes	0	4	5
482	b.b21x5	b.b25x1	3.11316	Yes	No	0	4	2
483	b.b21x7	b.b23x2	5.17851	Yes	No	0	5	6
484	b.b21x7	b.b24x6	9.35192	Yes	Yes	0	5	8
485	b.l21x2	b.l21x4	8.95237	Yes	No	0	4	4
486	b.l21x2	b.l21x5	3.27189	Yes	No	0	4	4
487	b.b25x3	b.l21x2	4.65353	No	Yes	0	5	4
488	b.b23x6	b.l21x5	5.21994	Yes	No	0	7	4
489	b.l21x7	b.l23x1	4.1827	No	Yes	0	5	6
490	b.l21x7	b.l23x2	6.13644	No	Yes	0	5	8
491	b.b23x6	b.l21x9	8.84066	Yes	No	0	7	6
492	b.b22x1	b.b22x2	2.81642	No	No	0	8	8
493	b.b22x1	b.l23x1	3.51051	No	Yes	2	8	6
494	b.b22x1	b.l25x6	3.99682	No	Yes	2	8	8
495	b.b22x2	b.b26x3	5.44047	No	No	0	8	6
496	b.b22x4	b.b26x3	2.95864	No	No	0	5	6
497	b.b22x4	b.b26x5	3.81509	No	No	0	5	7
498	b.b22x5	b.b23x2	8.19012	Yes	No	0	7	6
499	b.b23x1	b.l22x1	3.60028	Yes	No	0	5	9
500	b.l22x1	g.ctx3	7.0192	No	Yes	23	9	9
501	b.l22x1	g.ctx5	2.89103	No	No	23	9	9
502	b.l22x3	g.ctx3	9.02578	No	Yes	0	9	9
503	b.b24x7	b.l22x5	12.5777	No	Yes	14	9	9
504	b.l22x5	b.l24x2	7.74847	Yes	No	14	9	6
505	b.l22x5	g.h2x12	2.83992	Yes	No	14	9	7
506	b.l22x5	g.ctx6	3.96594	Yes	Yes	0	9	6
507	b.b23x1	b.b24x5	4.44298	Yes	No	0	5	5
508	b.b23x3	b.b24x5	4.20914	No	No	0	7	5
509	b.b23x3	b.b27x1	4.2826	No	No	0	7	6
510	b.b23x4	b.b23x6	3.97644	No	Yes	0	6	7
511	b.b23x6	b.l23x2	3.86048	Yes	Yes	0	7	8
512	b.b23x6	b.b24x4	11.0071	Yes	Yes	18	7	6
513	b.b23x6	b.b24x6	6.3607	Yes	Yes	18	7	8
514	b.l23x1	b.l25x6	15.7221	Yes	Yes	2	6	8
515	b.b24x2	b.l23x2	6.76531	No	Yes	0	5	8
516	b.b24x2	b.b25x6	3.2228	No	No	0	5	3
517	b.b24x3	b.b25x7	5.1257	No	No	0	5	7
518	b.b24x4	b.b24x6	3.88839	Yes	Yes	18	6	8
519	b.b24x4	b.b25x3	9.45539	Yes	No	18	6	5
520	b.b24x4	b.b25x6	3.72393	Yes	No	0	6	3
521	b.b24x6	b.b25x3	5.26042	Yes	No	18	8	5
522	b.b24x7	b.l24x3	8.18349	No	Yes	0	9	5
523	b.l24x2	g.h2x12	4.66424	No	No	14	6	7
524	b.b25x2	b.l24x3	4.472	No	Yes	0	2	5
525	b.b25x7	b.b28x6	14.9296	No	Yes	0	7	9
526	b.l25x3	b.l25x7	3.51407	Yes	No	0	9	7
527	b.b27x3	b.l25x3	6.60813	No	Yes	0	8	9
528	b.b27x5	b.l25x3	14.0918	No	Yes	12	9	9
529	b.l25x3	b.l27x2	8.10941	Yes	Yes	12	9	9
530	b.b28x4	b.l25x3	8.59779	Yes	Yes	12	6	9
531	b.l25x4	b.l27x2	6.04281	No	Yes	0	5	9
532	b.l25x5	b.l27x1	6.93599	No	Yes	0	7	9
533	b.l25x6	b.l27x1	21.0967	Yes	Yes	2	8	9
534	b.b26x1	b.l27x1	5.2896	No	Yes	0	9	9
535	b.b26x3	b.b27x3	3.19144	No	No	0	6	8
536	b.b26x5	b.b27x1	3.6361	No	No	0	7	6
537	b.l26x1	b.l26x3	6.60461	No	No	5	7	7
538	b.l26x3	b.l26x5	7.34027	No	No	0	7	5
539	b.l26x5	g.ctx4	5.23559	No	No	0	5	7
540	b.l26x5	g.ctx15	4.69769	No	Yes	0	5	9
541	b.l26x6	g.ctx16	4.48208	No	Yes	0	7	8
542	b.b27x3	b.b28x6	7.69969	No	Yes	0	8	9
543	b.b27x5	b.l27x2	8.43115	No	Yes	12	9	9
544	b.b28x2	b.l27x2	8.53723	No	Yes	0	4	9
545	b.b28x4	b.b28x6	6.45689	Yes	Yes	12	6	9
546	b.b28x5	g.ctx16	4.23552	No	Yes	7	5	8
547	b.b28x7	g.ctx14	7.95181	No	Yes	7	9	9
548	b.b28x7	g.ctx16	3.20687	No	Yes	7	9	8
549	g.h1x1	g.h1x5	2.94546	Yes	No	0	2	6
550	g.h1x10	g.h1x14	6.29627	No	No	0	9	9
551	g.l1x2	g.l1x4	5.57123	No	Yes	0	2	8
552	g.h2x3	g.l1x5	4.0668	No	No	0	5	4
553	g.h2x3	g.h2x7	3.41183	No	No	0	5	5
554	g.h2x11	g.h2x15	15.7833	Yes	No	0	6	6
555	g.ctx2	g.h2x15	4.03577	No	No	0	3	6
556	g.ctx3	g.ctx4	3.85555	Yes	No	0	9	7
557	g.ctx3	g.ctx5	2.82424	Yes	No	23	9	9
558	g.ctx3	g.ctx6	7.30279	Yes	Yes	0	9	6
559	g.ctx10	g.ctx9	3.603	No	No	7	5	6
560	g.ctx13	g.ctx9	3.26139	No	No	7	5	6
561	g.ctx14	g.ctx9	2.86098	Yes	No	7	9	6
562	g.ctx10	g.ctx13	6.65809	No	No	7	5	5
563	g.ctx12	g.ctx13	2.83619	No	No	0	6	5
564	g.ctx14	g.ctx15	5.3868	Yes	Yes	7	9	9
565	g.ctx14	g.ctx16	3.45577	Yes	Yes	7	9	8
566	g.ctx15	g.ctx16	4.16367	Yes	Yes	7	9	8
567	3x32	Lig	12.3911	No	Yes	1	8	0
568	3x33	Lig	11.1621	No	Yes	0	8	0
569	3x36	Lig	7.8178	No	Yes	1	7	0
570	3x37	Lig	2.86032	Yes	Yes	1	8	0
571	E2x52	Lig	3.53891	No	Yes	1	6	0
572	5x43	Lig	3.81639	No	Yes	0	8	0
573	5x461	Lig	3.43582	No	Yes	1	8	0
574	6x48	Lig	3.93769	Yes	Yes	1	8	0
575	6x51	Lig	12.5075	Yes	Yes	1	8	0
576	6x52	Lig	5.56849	Yes	Yes	1	7	0
577	7x38	Lig	8.08708	Yes	Yes	1	7	0
578	7x42	Lig	5.78002	Yes	Yes	1	8	0
579	1x39	2x61	4.91675	No	No	0	7	7
580	1x39	7x39	9.24983	No	Yes	0	7	8
581	1x43	2x57	4.65917	No	Yes	0	7	8
582	1x46	1x50	2.92813	Yes	Yes	0	8	9
583	1x46	2x54	2.8645	Yes	No	1	8	8
584	1x46	7x47	5.66831	Yes	No	0	8	7
585	1x50	2x50	8.99406	Yes	Yes	0	9	9
586	1x50	2x51	3.56499	Yes	No	0	9	8
587	1x50	7x50	8.03761	Yes	No	0	9	9
588	1x51	2x51	2.79546	No	No	0	5	8
589	1x52	8x54	4.3668	No	Yes	0	8	8
590	1x53	2x47	3.28361	No	No	0	9	9
591	1x53	7x54	3.15504	No	No	0	9	8
592	1x57	2x44	6.31639	No	No	0	8	6
593	1x60	I1x50	5.74238	Yes	Yes	0	7	8
594	1x60	8x53	2.96179	Yes	No	0	7	8
595	2x40	I1x50	3.45187	No	Yes	25	9	8
596	8x49	I1x50	2.94433	No	Yes	0	7	8
597	8x50	I1x50	7.85498	Yes	Yes	25	8	8
598	2x41	I1x51	3.00756	No	No	0	6	8
599	2x37	2x40	6.53689	No	No	0	8	9
600	2x38	I2x57	2.84244	No	No	0	7	8
601	2x39	3x49	4.69941	No	Yes	0	8	9
602	2x40	8x50	5.18247	No	Yes	25	9	8
603	2x42	3x45	4.30857	Yes	No	1	8	8
604	2x42	3x46	3.34081	Yes	Yes	1	8	9
605	2x42	3x49	6.09429	Yes	Yes	1	8	9
606	2x42	4x42	3.18196	Yes	No	0	8	7
607	2x42	4x45	3.23107	Yes	No	1	8	6
608	2x42	4x46	3.33742	Yes	No	0	8	8
609	2x45	3x42	7.61347	No	Yes	1	9	8
610	2x45	4x46	7.50427	No	No	0	9	8
611	2x46	2x50	3.73558	Yes	Yes	1	9	9
612	2x46	3x42	4.79173	Yes	Yes	1	9	8
613	2x46	3x43	3.86456	Yes	Yes	1	9	8
614	2x46	7x49	6.45891	Yes	Yes	1	9	9
615	2x49	4x50	3.97937	No	Yes	0	9	9
616	2x50	3x39	4.14244	Yes	No	0	9	9
617	2x50	7x46	8.96853	Yes	No	0	9	9
618	2x50	7x49	7.09981	Yes	Yes	1	9	9
619	2x52	3x35	4.54784	No	No	0	7	7
620	2x53	3x35	4.61668	No	No	0	8	7
621	2x53	7x46	4.63821	No	No	0	8	9
622	2x54	2x57	3.16217	No	Yes	1	8	8
623	2x551	3x31	3.49082	No	No	0	6	5
624	2x56	3x28	3.39971	Yes	Yes	0	8	6
625	2x56	3x32	7.97594	Yes	No	1	8	8
626	2x56	7x42	3.88703	Yes	Yes	1	8	8
627	2x57	7x39	3.22795	Yes	Yes	1	8	8
628	2x57	7x42	6.46597	Yes	Yes	1	8	8
629	2x59	3x24	3.15662	No	Yes	0	6	6
630	2x59	3x28	7.53332	No	Yes	0	6	6
631	2x60	3x28	4.3484	Yes	Yes	0	7	6
632	2x60	7x39	3.19714	Yes	Yes	1	7	8
633	2x60	7x42	4.85844	Yes	Yes	1	7	8
634	2x63	E1x50	5.16411	No	Yes	0	6	9
635	2x64	7x35	4.68698	No	No	0	7	6
636	E1x49	E1x51	3.402	No	No	0	5	5
637	E1x50	E1x52	9.33951	Yes	No	15	9	7
638	3x24	E1x50	2.83244	Yes	Yes	15	6	9
639	3x25	E1x50	5.92825	No	Yes	15	9	9
640	3x28	E1x50	5.98272	Yes	Yes	0	6	9
641	E1x50	E2x50	8.85991	Yes	No	15	9	9
642	E1x51	E1x52	3.29508	No	No	0	5	7
643	3x24	E1x52	5.53869	Yes	No	15	6	7
644	3x22	E2	4.93198	No	Yes	0	4	4
645	3x25	E2x50	7.01627	No	No	15	9	9
646	3x26	E2	3.07375	No	Yes	1	7	4
647	3x29	E2x52	3.31722	No	No	0	7	6
648	3x30	4x61	3.14362	No	No	0	7	6
649	3x32	7x42	9.00539	No	Yes	1	8	8
650	3x33	4x57	7.03242	No	No	0	8	8
651	3x34	4x54	2.90471	No	No	0	6	5
652	3x34	4x57	3.15886	No	No	0	6	8
653	3x36	6x48	4.5365	No	Yes	1	7	8
654	3x37	3x41	2.8639	Yes	Yes	0	8	7
655	3x37	4x53	4.56707	Yes	No	0	8	8
656	3x37	5x461	5.41446	Yes	No	1	8	8
657	3x38	4x50	6.25106	No	Yes	0	8	9
658	3x40	5x50	2.80019	No	Yes	0	8	9
659	3x40	6x44	3.59117	No	Yes	1	8	9
660	3x40	6x48	8.03967	No	Yes	1	8	8
661	3x41	4x49	2.99223	Yes	No	0	7	8
662	3x41	4x52	3.20449	Yes	No	0	7	5
663	3x41	5x50	2.86183	Yes	Yes	0	7	9
664	3x42	4x49	5.5505	Yes	No	0	8	8
665	3x42	4x50	3.26176	Yes	Yes	1	8	9
666	3x43	6x44	2.84738	Yes	Yes	1	8	9
667	3x43	7x49	5.03998	Yes	Yes	1	8	9
668	3x43	7x53	6.92763	Yes	Yes	1	8	9
669	3x44	5x53	3.62849	No	No	0	7	7
670	3x45	4x45	4.87876	No	No	1	8	6
671	3x46	3x50	4.47599	Yes	Yes	1	9	9
672	3x46	7x53	4.85778	Yes	Yes	1	9	9
673	3x47	5x54	4.62588	No	No	1	9	9
674	3x47	5x57	3.83164	No	No	0	9	7
675	3x47	5x58	6.58618	No	Yes	1	9	9
676	3x48	3x52	3.61837	No	No	0	6	5
677	3x48	5x57	2.90794	No	No	0	6	7
678	3x49	I2x57	4.96744	Yes	No	1	9	8
679	3x50	5x58	3.9959	Yes	Yes	1	9	9
680	3x50	7x53	4.78365	Yes	Yes	1	9	9
681	3x51	3x55	11.1748	No	No	0	9	8
682	3x51	5x57	7.88839	No	No	0	9	7
683	3x51	5x60	7.05617	No	No	0	9	7
684	3x53	I2x53	5.64146	No	Yes	1	8	8
685	3x54	5x61	3.01745	No	No	0	9	9
686	3x56	I2x52	6.08294	No	No	0	7	6
687	I2x52	I2x56	2.84973	No	No	0	6	5
688	I2x53	I2x57	7.31364	Yes	No	1	8	8
689	4x60	5x39	3.87187	No	Yes	0	7	8
690	E2	E2	48.4232	Yes	Yes	1	4	4
691	E2	E2x51	9.75891	Yes	No	0	4	5
692	5x39	E2	6.39511	Yes	Yes	1	8	4
693	5x36	5x38	2.95181	No	No	0	6	5
694	5x36	5x39	3.12926	No	Yes	1	6	8
695	5x37	6x60	3.46984	No	No	0	4	5
696	5x39	5x43	5.67246	Yes	No	0	8	8
697	5x44	6x52	3.61335	No	Yes	0	7	7
698	5x44	6x56	4.1008	No	No	0	7	7
699	5x45	5x48	3.53833	No	No	0	5	7
700	5x47	5x48	6.0698	Yes	No	0	8	7
701	5x47	5x51	5.8367	Yes	No	1	8	7
702	5x47	6x44	4.84897	Yes	Yes	1	8	9
703	5x47	6x48	3.74614	Yes	Yes	1	8	8
704	5x47	6x49	4.26822	Yes	Yes	0	8	7
705	5x47	6x52	18.6109	Yes	Yes	1	8	7
706	5x48	6x56	3.23065	No	No	0	7	7
707	5x49	5x50	3.3038	No	Yes	0	6	9
708	5x51	6x44	3.98698	No	Yes	1	7	9
709	5x54	5x58	2.8074	No	Yes	1	9	9
710	5x54	6x44	5.42648	No	Yes	1	9	9
711	5x55	6x41	3.31769	No	No	0	6	8
712	5x56	5x60	3.02962	No	No	0	5	7
713	5x58	6x37	5.75837	Yes	No	0	9	8
714	5x58	6x40	4.11448	Yes	No	0	9	8
715	5x58	6x41	4.41674	Yes	No	0	9	8
716	5x62	5x66	7.03335	Yes	No	0	6	7
717	5x62	6x34	4.83589	Yes	No	0	6	8
718	5x66	6x30	3.2112	No	No	0	7	8
719	6x40	7x53	4.67369	No	Yes	0	8	9
720	6x43	7x52	2.85745	No	No	0	7	8
721	6x44	6x48	4.97529	Yes	Yes	1	9	8
722	6x47	7x45	8.07264	No	No	0	8	9
723	6x48	6x52	5.04786	Yes	Yes	1	8	7
724	6x48	7x41	8.00332	Yes	No	0	8	8
725	6x48	7x45	9.74538	Yes	No	0	8	9
726	6x49	6x50	2.98028	Yes	No	0	7	9
727	6x50	7x37	3.75111	No	No	0	9	6
728	6x51	6x52	5.34818	Yes	Yes	1	8	7
729	6x51	6x55	6.07262	Yes	No	1	8	8
730	6x51	7x38	5.62684	Yes	Yes	1	8	7
731	6x54	7x37	3.6844	No	No	0	6	6
732	6x58	E3	6.54251	No	Yes	1	4	4
733	6x61	E3	5.4571	No	Yes	0	5	4
734	7x34	E3	2.92593	No	Yes	1	4	4
735	7x30	7x33	4.13448	Yes	No	0	7	6
736	7x38	7x42	6.78735	Yes	Yes	1	7	8
737	7x39	7x42	7.71662	Yes	Yes	1	8	8
738	7x45	7x49	8.053	No	Yes	0	9	9
739	7x52	7x53	3.75063	No	Yes	0	8	9
740	7x54	8x50	6.00815	No	Yes	0	8	8
741	8x47	8x49	6.29689	No	No	0	9	7
742	8x47	8x50	4.74727	No	Yes	0	9	8
743	G.h2s4.02	b.l27x1	3.96166	No	Yes	2	9	9
744	G.HG.17	G.hgh4.01	3.04592	No	Yes	0	4	3
745	b.b23x1	g.ctx6	2.98448	Yes	Yes	0	5	6
746	b.b1x3	g.ctx17	2.88896	No	No	0	7	7
747	1x60	I1x49	4.37388	Yes	No	0	7	6
748	3x44	5x50	3.19386	No	Yes	0	7	9
749	5x36	E2	4.42949	No	Yes	1	6	4
750	6x55	Lig	3.59644	No	Yes	1	8	0
751	b.h2x1	b.h2x5	3.34572	Yes	No	0	5	5
752	b.b12x4	b.b12x6	4.46538	No	Yes	2	4	8
753	2x53	2x56	2.90892	No	Yes	0	8	8
754	G.H2.05	G.H2.06	3.00237	No	Yes	2	9	8
755	G.H2.05	b.l17x6	6.42675	No	Yes	2	9	9
756	G.H4.14	G.H4.17	2.83477	Yes	No	0	3	3
757	b.b24x1	b.l25x5	2.91809	No	No	0	4	7
758	1x46	2x57	3.01404	Yes	Yes	1	8	8
759	I1x48	I1x51	3.80508	No	No	0	7	8
760	E2	E2x52	5.76779	Yes	No	1	4	6
761	G.S2.03	G.S2.05	3.76668	No	No	2	5	6
762	G.H3.03	G.H3.07	3.18616	Yes	No	0	8	6
763	G.HG.02	G.s6h5.02	3.38114	No	No	0	5	9
764	G.hgh4.03	G.hgh4.04	3.8584	No	No	0	7	5
765	G.s6h5.01	G.s6h5.05	3.27586	Yes	No	9	4	8
766	G.H5.03	G.s6h5.05	4.23042	Yes	No	9	4	8
767	G.H5.22	G.H5.23	3.34424	No	No	0	5	4
768	G.H3.03	G.H3.06	3.12273	Yes	Yes	0	8	9
769	b.l17x3	b.l19x2	3.90949	Yes	Yes	3	9	9
770	4x64	E2	5.47598	No	Yes	1	6	4
771	4x38	4x41	3.59844	No	No	0	8	7
772	5x59	5x63	3.72974	No	No	0	3	5
773	G.HG.02	G.HG.03	2.9221	No	Yes	0	5	9
774	1x54	2x44	2.78844	No	No	0	7	6
775	2x45	4x50	4.40555	No	Yes	1	9	9
776	3x49	I2x53	7.26101	Yes	Yes	1	9	8
777	3x52	I2x53	5.62635	No	Yes	0	5	8
778	6x36	7x56	5.44924	No	No	0	8	8
779	6x58	7x34	3.58529	No	No	1	4	4
780	5x72	G.H5.17	3.52033	No	Yes	11	0	6
781	G.H3.01	G.H3.04	2.9625	Yes	No	0	9	4
782	G.H4.08	G.H4.12	3.73987	Yes	Yes	6	5	7
783	3x30	4x58	3.72926	No	No	0	7	6
784	b.1x1	b.1x5	3.6069	Yes	No	0	0	3
785	b.1x2	b.1x5	3.04897	No	No	0	1	3
786	G.hgh4.01	G.s4h3.15	6.0152	Yes	No	0	3	6
787	G.H3.13	G.h4s6.13	12.6435	Yes	No	0	8	0
788	G.H3.17	b.l23x1	2.92708	Yes	Yes	2	4	6
789	G.H4.07	G.HG.01	3.732	No	Yes	6	7	9
790	G.H4.10	G.hgh4.08	5.11162	Yes	No	0	3	7
791	G.H4.13	G.hgh4.08	4.05231	Yes	No	0	5	7
792	G.H4.08	G.hgh4.14	3.14074	Yes	No	0	5	0
793	G.H4.07	G.hgh4.20	2.93625	No	No	0	7	0
794	G.H4.01	G.hgh4.21	2.99937	No	No	0	3	0
795	G.H4.02	G.hgh4.21	4.06809	No	No	0	3	0
796	G.h4s6.10	G.h4s6.12	3.06424	No	No	0	3	7
797	G.S6.02	G.h4s6.20	3.23272	Yes	No	11	5	0
798	G.H5.10	G.S6.04	4.99844	No	No	0	4	5
799	3x30	4x62	2.81619	No	No	0	7	6
800	E2	E3	4.63843	Yes	Yes	1	4	4
801	5x40	6x55	3.52373	No	No	0	7	8
802	G.S1.02	I2x51	3.05731	No	Yes	0	5	6
803	2x60	7x38	3.55067	Yes	Yes	1	7	7
804	G.H5.02	G.s6h5.05	2.83821	No	No	0	9	8
805	G.S1.03	G.hns1.01	5.50478	No	No	0	9	3
806	G.H2.01	G.H2.03	3.50555	No	No	2	9	8
807	G.H2.01	b.l13x6	2.88114	No	Yes	2	9	9
808	G.h2s4.03	b.l1x6	3.09946	No	Yes	0	7	9
809	G.H4.08	G.S6.05	3.09064	Yes	Yes	6	5	9
810	G.H5.17	G.h4s6.20	5.04013	Yes	No	11	6	0
811	5x72	G.h4s6.20	3.66904	No	No	11	0	0
812	G.H4.04	G.hgh4.20	2.7702	No	No	0	4	0
813	b.h2x1	g.h2x5	2.76526	Yes	No	0	5	6
814	6x49	6x53	2.76299	Yes	No	0	7	7
815	G.HG.16	G.hgh4.05	2.75457	No	Yes	0	7	6
816	G.H3.02	G.H4.11	2.75442	No	No	0	9	6
817	b.b2x4	b.b6x5	2.75057	No	Yes	0	6	6
818	G.S4.01	G.S5.03	2.74971	No	No	0	7	6
819	b.b10x3	b.b11x4	2.74156	No	Yes	0	8	9
820	G.HG.01	G.s6h5.02	2.73756	Yes	No	0	9	9
821	b.l14x1	b.l14x3	2.69827	No	No	0	4	5
822	G.H1.01	G.s1h1.01	2.69823	No	No	0	9	9
823	G.H5.15	I2x50	2.69287	No	No	0	7	8
824	I1x48	b.l25x4	2.69278	No	No	0	7	5
825	G.HG.14	G.HG.16	2.68331	No	No	0	7	7
826	G.h2s4.01	G.h2s4.04	2.67226	Yes	No	0	7	5
827	4x63	E2	2.65405	No	Yes	0	5	4
828	6x32	G.H5.24	2.65214	No	No	0	8	4
829	2x60	2x64	2.62731	Yes	No	0	7	7
830	1x56	8x54	2.62635	No	Yes	0	8	8
831	5x40	6x59	2.62177	No	No	0	7	7
832	2x38	4x39	2.62037	No	No	0	7	5
833	b.l21x8	b.l23x1	2.61116	No	Yes	0	4	6
834	G.hgh4.05	G.hgh4.07	2.60611	Yes	No	0	6	3
835	g.h1x12	g.h1x9	2.59539	No	No	0	6	6
836	4x61	E2	2.59466	No	Yes	1	6	4
837	6x45	6x49	2.59027	No	Yes	0	7	7
838	G.H4.04	G.hgh4.16	2.57956	No	No	0	4	0
839	8x50	8x54	2.56293	Yes	Yes	0	8	8
840	5x41	6x56	2.55055	No	No	0	7	7
841	G.H4.03	G.HG.01	2.54543	No	Yes	0	5	9
842	b.1x16	b.1x17	2.53667	No	No	0	4	2
843	7x30	E3	2.52754	Yes	Yes	0	7	4
844	b.b19x1	b.l18x1	2.52706	No	Yes	0	6	6
845	G.hgh4.17	G.hgh4.20	2.522	No	No	0	0	0
846	b.b23x5	b.b24x3	2.50475	No	No	0	7	5
847	b.b15x1	b.l16x1	2.49668	Yes	No	0	9	4
848	b.b10x5	b.l6x2	2.49559	Yes	No	0	9	6
849	2x66	E1x51	2.49196	No	No	0	5	5
850	5x65	G.H5.20	2.49071	No	Yes	0	8	8
851	b.b5x3	b.l1x2	2.48741	Yes	No	0	9	9
852	1x43	2x58	2.48632	No	No	0	7	9
853	I1x49	b.l25x4	2.47881	No	No	0	6	5
854	1x36	2x65	2.47227	No	No	0	5	6
855	b.l26x2	b.l2x2	2.45237	No	No	0	1	1
856	G.H5.21	G.H5.26	2.44685	No	Yes	0	9	7
857	b.l8x4	b.l8x5	2.44213	No	No	0	3	3
858	4x38	4x40	2.42967	No	No	0	8	6
859	8x48	G.H5.24	2.42747	No	No	0	6	4
860	G.H4.01	G.HG.14	2.42741	No	No	0	3	7
861	1x42	7x39	2.42641	No	Yes	0	7	8
862	b.lhb1x1	b.lhb1x2	2.42212	No	No	0	1	1
863	6x33	G.H5.25	2.421	No	Yes	0	8	8
864	b.1x12	g.h1x11	2.41878	No	No	0	6	9
865	g.ctx7	g.ctx8	2.40557	No	No	0	4	8
866	3x37	4x56	2.40046	Yes	No	0	8	8
867	b.h2x4	g.h2x5	2.39806	No	No	0	3	6
868	4x56	5x46	2.38406	No	No	0	8	5
869	2x55	2x551	2.37481	No	No	0	6	6
870	b.b28x1	b.b28x2	2.37283	No	No	0	4	4
871	b.b27x4	b.b28x3	2.35046	No	Yes	0	5	7
872	G.H2.02	b.l9x6	2.34062	No	Yes	0	9	8
873	4x59	4x60	2.33747	No	No	0	8	7
874	1x47	2x51	2.32471	No	No	0	7	8
875	b.b16x3	b.b19x2	2.32206	No	Yes	0	6	6
876	7x30	7x32	2.31968	Yes	No	0	7	3
877	b.1x22	g.l1x4	2.302	No	Yes	0	3	8
878	G.H5.15	I2x54	2.29322	No	No	0	7	6
879	b.l22x2	g.ctx3	2.28587	No	Yes	0	1	9
880	G.HN.39	b.b5x5	2.26695	No	Yes	0	5	5
881	b.1x12	b.1x9	2.2575	No	No	0	6	4
882	5x37	6x59	2.24757	No	No	0	4	7
883	g.h1x11	g.h1x7	2.23431	No	No	0	9	2
884	b.b26x4	b.b2x5	2.22949	No	Yes	0	5	7
885	G.h4s6.02	G.h4s6.11	2.22174	No	No	0	4	3
886	b.l7x5	b.l9x1	2.21975	No	No	0	6	5
887	g.ctx1	g.ctx2	2.21458	No	No	0	1	3
888	G.HN.11	G.HN.33	2.20496	No	No	0	2	4
889	b.b10x5	b.b6x4	2.19973	Yes	No	0	9	7
890	b.1x13	b.1x9	2.19855	No	No	0	1	4
891	6x57	E3	2.19593	No	Yes	0	6	4
892	b.b18x4	b.b22x5	2.18217	No	Yes	0	3	7
893	b.b2x2	b.b6x3	2.1807	No	No	0	7	8
894	G.hgh4.17	G.hgh4.18	2.17231	No	No	0	0	0
895	4x65	E2	2.1721	No	Yes	1	0	4
896	b.l22x2	b.l26x4	2.17032	No	No	0	1	9
897	g.h2x14	g.h2x15	2.16927	No	No	0	4	6
898	b.b24x2	b.l25x1	2.16716	No	No	0	5	3
899	b.1x15	g.h1x15	2.16337	No	No	0	7	8
900	G.h3s5.01	G.h3s5.02	2.15451	No	No	0	9	3
901	b.b13x1	b.b9x2	2.14727	No	No	0	4	5
902	6x43	7x48	2.14452	No	No	0	7	6
903	1x47	2x55	2.13623	No	No	0	7	6
904	5x62	6x37	2.13338	Yes	No	0	6	8
905	3x54	5x64	2.13318	No	No	0	9	6
906	b.l13x5	b.l15x2	2.13232	No	Yes	0	5	9
907	b.b1x1	b.lhb1x10	2.13063	No	No	0	5	4
908	1x57	8x50	2.12279	No	Yes	0	8	8
909	G.H3.14	G.h4s6.08	2.12187	Yes	No	0	5	4
910	b.b7x5	b.l7x1	2.11	No	No	0	9	9
911	b.b8x3	b.b9x1	2.10787	Yes	No	0	6	4
912	G.HN.43	b.b5x6	2.10645	No	No	0	9	6
913	1x59	1x60	2.09504	No	Yes	0	6	7
914	G.HN.51	G.hns1.02	2.08569	No	No	0	5	4
915	8x48	8x51	2.08119	No	No	0	6	9
916	b.1x18	g.l1x4	2.08071	No	Yes	0	4	8
917	b.b21x5	b.h2x2	2.078	Yes	No	0	4	1
918	G.H4.08	G.hgh4.11	2.07746	Yes	No	0	5	0
919	G.HN.37	G.HN.41	2.07719	No	No	0	3	4
920	1x54	2x48	2.06661	No	No	0	7	7
921	7x51	7x55	2.06357	No	No	0	6	6
922	b.l10x4	b.l12x1	2.05188	No	Yes	0	3	6
923	7x55	8x54	2.03351	No	Yes	0	6	8
924	6x36	G.H5.25	2.02863	No	Yes	0	8	8
925	b.l24x3	b.lhb1x5	2.01532	Yes	No	0	5	1
926	7x43	7x48	1.99324	No	No	0	5	6
927	G.h3s5.02	G.h4s6.12	1.9928	No	No	0	3	7
928	G.hfs2.06	b.l7x4	1.99194	No	Yes	0	9	9
929	G.S5.07	G.s1h1.06	1.97927	Yes	No	0	8	9
930	b.b17x2	g.h1x13	1.97875	No	No	0	3	1
931	G.hgh4.02	G.hgh4.04	1.96837	Yes	No	0	6	5
932	b.b9x2	b.l12x1	1.96591	No	Yes	0	5	6
933	4x47	4x51	1.9599	No	No	0	5	5
934	b.b12x6	b.l9x2	1.9598	Yes	No	0	8	5
935	b.1x4	g.h1x5	1.94228	No	No	0	8	6
936	G.H1.09	G.S2.04	1.94019	No	No	0	8	9
937	g.ctx6	g.ctx7	1.9221	Yes	No	0	6	4
938	G.H3.01	G.s1h1.03	1.9129	Yes	No	0	9	8
939	b.l13x1	b.l13x2	1.88994	No	No	0	2	6
940	b.b18x5	b.l18x4	1.88759	Yes	No	0	5	7
941	3x27	3x31	1.87371	No	No	0	5	5
942	b.b22x3	b.b23x2	1.86894	No	No	0	6	6
943	2x43	3x46	1.85987	No	Yes	0	8	9
944	1x45	7x47	1.85939	No	No	0	5	7
945	1x59	8x57	1.84861	No	No	0	6	7
946	1x49	7x50	1.84662	No	No	0	9	9
947	G.H2.01	b.b12x1	1.84657	No	No	0	9	6
948	G.h4s6.09	G.h4s6.10	1.83288	No	No	0	3	3
949	g.h1x12	g.h1x8	1.82764	No	Yes	0	6	7
950	6x32	G.H5.26	1.82704	No	Yes	0	8	7
951	1x48	1x49	1.81699	No	No	0	4	9
952	1x55	8x57	1.80259	No	No	0	5	7
953	G.h3s5.01	G.h4s6.04	1.79777	No	No	0	9	5
954	b.1x2	b.1x6	1.79496	No	No	0	1	3
955	6x39	7x52	1.78017	No	No	0	7	8
956	3x55	3x56	1.74761	No	No	0	8	7
957	1x60	8x56	1.74141	Yes	No	0	7	6
958	b.h2x3	b.lh12x3	1.7247	No	No	0	1	4
959	6x35	6x39	1.70906	No	No	0	7	7
960	2x62	2x66	1.70403	No	No	0	6	5
961	G.hgh4.10	G.hgh4.11	1.70301	No	No	0	0	0
962	7x36	7x40	1.69174	No	No	0	4	8
963	g.ctx11	g.ctx17	1.6898	No	No	0	4	7
964	b.1x3	b.1x7	1.68974	No	No	0	1	8
965	5x69	6x30	1.67846	No	No	0	6	8
966	3x21	3x24	1.62441	No	Yes	0	7	6
967	b.b16x2	b.l17x1	1.61889	No	No	0	5	2
968	b.b20x1	b.l21x5	1.59911	No	No	0	5	4
969	G.HG.09	G.hgh4.21	1.58973	No	No	0	6	0
970	b.1x4	g.h1x8	1.57204	No	Yes	0	8	7
971	G.H1.03	G.s1h1.06	1.572	No	No	0	9	9
972	G.H5.02	G.s6h5.04	1.562	No	No	0	9	9
973	G.H5.01	G.H5.02	1.55261	No	No	0	9	9
974	b.b21x7	b.l24x1	1.54145	Yes	No	0	5	5
975	b.1x11	b.1x14	1.53463	No	No	0	8	4
976	G.hns1.03	I2x55	1.53167	Yes	No	0	4	5
977	G.HN.46	G.HN.50	1.50068	No	No	0	4	5
978	b.l2x2	b.l6x2	1.48048	No	No	0	1	6
979	G.HN.42	G.HN.45	1.47933	No	No	0	4	4
980	b.b24x5	b.b25x5	1.46206	No	No	0	5	4
981	6x50	7x40	1.45736	No	No	0	9	8
982	b.lh12x2	b.lh12x3	1.45223	No	No	0	8	4
983	b.b25x4	b.lhb1x6	1.429	No	Yes	0	4	3
984	8x52	8x55	1.4217	No	No	0	6	6
985	b.b28x6	b.l25x2	1.40834	Yes	No	0	9	5
986	b.1x1	g.h1x1	1.40348	Yes	Yes	0	0	2
987	5x71	G.H5.13	1.39008	No	Yes	0	5	6
988	b.l17x1	b.l17x2	1.37792	No	No	0	2	6
989	4x41	I2x56	1.36697	No	No	0	7	5
990	4x48	4x52	1.34781	No	No	0	3	5
991	G.HG.03	G.HG.06	1.34383	Yes	No	0	9	5
992	b.lhb1x6	b.lhb1x7	1.33712	Yes	No	0	3	1
993	6x31	6x34	1.32664	No	No	0	6	8
994	G.H4.06	G.hgh4.05	1.30818	No	Yes	0	4	6
995	1x36	2x61	1.29801	No	No	0	5	7
996	G.H2.04	G.H3.11	1.28664	No	No	0	9	5
997	g.h1x6	g.h1x9	1.28569	No	No	0	4	6
998	5x69	6x26	1.28064	No	No	0	6	5
999	G.s1h1.02	G.s1h1.05	1.2792	No	No	0	7	9
1000	4x40	4x44	1.26603	No	No	0	6	3
1001	G.S2.07	G.s2s3.02	1.25832	No	No	0	9	4
1002	4x65	4x66	1.2558	No	No	0	0	0
1003	7x30	7x31	1.23228	Yes	No	0	7	2
1004	G.HN.11	G.HN.34	1.22356	No	No	0	2	3
1005	G.HN.46	G.HN.49	1.21732	No	No	0	4	4
1006	G.H4.16	I3	1.2115	Yes	Yes	0	8	0
1007	b.1x3	b.ntx2	1.20061	No	No	0	1	0
1008	b.1x10	b.1x14	1.19214	No	No	0	1	4
1009	b.b16x1	b.l17x3	1.18793	No	Yes	0	4	9
1010	g.ctx17	g.ctx18	1.18152	No	No	0	7	6
1011	G.HG.16	G.hgh4.06	1.14289	No	No	0	7	7
1012	5x70	5x71	1.13313	No	No	0	6	5
1013	b.1x14	g.h1x15	1.12828	No	No	0	4	8
1014	1x35	2x65	1.104	No	No	0	5	6
1015	G.H5.18	G.H5.21	1.09429	No	No	0	5	9
1016	G.H1.03	G.s6h5.03	1.09426	No	No	0	9	7
1017	5x67	5x71	1.08204	No	No	0	6	5
1018	g.h2x13	g.h2x9	1.06194	No	No	0	1	4
1019	b.1x8	g.h1x8	1.05614	No	Yes	0	5	7
1020	b.l8x3	b.l8x6	1.03765	No	No	0	3	4
1021	G.HN.45	G.HN.49	1.03446	No	No	0	4	4
1022	G.HG.12	G.HG.13	1.02377	No	No	0	2	1
1023	G.H3.01	G.s4h3.08	1.00881	Yes	No	0	9	5
1024	1x30	1x31	1.00253	No	Yes	0	0	4
1025	1x38	1x42	1.00168	No	No	0	5	7
1026	b.l21x2	b.l21x3	0.997593	Yes	No	0	4	3
1027	1x40	2x61	0.987616	No	No	0	4	7
1028	G.HN.38	G.HN.42	0.973697	No	No	0	3	4
1029	g.h1x3	g.h1x6	0.972683	No	No	0	3	4
1030	1x54	1x58	0.972199	No	No	0	7	4
1031	G.s4h3.12	G.s4h3.13	0.969117	No	No	0	8	4
1032	G.hgh4.15	G.hgh4.16	0.951157	No	No	0	0	0
1033	G.s3h2.01	G.s3h2.02	0.934986	No	No	0	9	9
1034	4x39	4x43	0.923995	No	No	0	5	4
1035	8x48	8x52	0.922657	No	No	0	6	6
1036	5x74	I3	0.912685	No	Yes	0	0	0
1037	b.1x16	b.1x20	0.90235	No	No	0	4	2
1038	G.HN.34	G.HN.37	0.895056	No	No	0	3	3
1039	G.S2.02	G.s3h2.01	0.894028	No	No	0	9	9
1040	G.HN.44	G.HN.48	0.874739	No	No	0	6	3
1041	b.1x3	b.ntx3	0.866368	No	No	0	1	0
1042	b.lhb1x2	b.lhb1x3	0.851525	No	Yes	0	1	2
1043	G.HN.30	G.HN.32	0.842579	No	No	0	7	5
1044	5x79	G.h4s6.03	0.835296	No	No	0	0	8
1045	5x42	5x46	0.830019	No	No	0	5	5
1046	1x34	1x38	0.823877	No	No	0	3	5
1047	g.ctx6	g.h2x16	0.821941	Yes	No	0	6	4
1048	1x44	1x48	0.802694	No	No	0	4	4
1049	4x51	4x55	0.795906	No	No	0	5	5
1050	G.H1.02	G.H1.03	0.772762	No	No	0	9	9
1051	1x52	8x58	0.768079	No	No	0	8	7
1052	G.H3.03	G.s4h3.14	0.765716	Yes	No	0	8	4
1053	5x78	G.hgh4.13	0.762741	No	Yes	0	0	0
1054	5x76	G.h4s6.03	0.74787	No	No	0	0	8
1055	CT	b.l23x2	0.744583	No	Yes	0	0	8
1056	5x62	5x63	0.734642	Yes	No	0	6	5
1057	G.hns1.03	I2x52	0.729	Yes	No	0	4	6
1058	1x37	1x41	0.720347	No	No	0	4	4
1059	4x64	4x68	0.715	No	No	0	6	0
1060	6x25	6x29	0.714579	No	No	0	4	7
1061	b.1x1	g.ntx4	0.707463	Yes	No	0	0	0
1062	1x32	2x65	0.70314	No	No	0	4	6
1063	1x29	1x30	0.69809	No	No	0	0	0
1064	G.hgh4.11	G.hgh4.13	0.691704	No	Yes	0	0	0
1065	4x36	G.HN.52	0.689889	No	No	0	0	4
1066	6x27	6x31	0.686975	No	No	0	5	6
1067	4x39	G.HN.52	0.685278	No	No	0	5	4
1068	b.1x1	g.ntx8	0.680926	Yes	No	0	0	4
1069	G.HG.10	G.HG.12	0.672537	No	No	0	0	2
1070	G.HN.53	G.hns1.03	0.666882	No	Yes	0	1	4
1071	G.HN.29	G.HN.33	0.664389	No	No	0	0	4
1072	G.H1.09	G.H1.11	0.636593	No	No	0	8	8
1073	G.HN.26	G.HN.30	0.62875	No	No	0	0	7
1074	g.h1x2	g.h1x5	0.598117	No	No	0	2	6
1075	3x23	3x26	0.594338	No	No	0	4	7
1076	g.h1x1	g.ntx6	0.591111	Yes	No	0	2	0
1077	5x73	6x28	0.59	No	No	0	0	5
1078	G.s4h3.07	G.s4h3.15	0.581844	No	No	0	8	6
1079	1x30	NT	0.577667	No	No	0	0	0
1080	6x41	6x42	0.577406	No	No	0	8	6
1081	G.H1.06	G.H1.10	0.573877	No	No	0	6	7
1082	1x41	1x45	0.56866	No	No	0	4	5
1083	g.l1x3	g.l1x5	0.545525	No	No	0	1	4
1084	G.s4h3.11	G.s4h3.14	0.543512	No	No	0	9	4
1085	G.H1.06	G.H1.07	0.543473	No	No	0	6	9
1086	G.s4h3.08	G.s4h3.10	0.53435	No	No	0	5	4
1087	G.H1.12	G.S2.06	0.525688	No	Yes	0	7	3
1088	6x28	6x31	0.520252	No	No	0	5	6
1089	1x32	NT	0.519815	No	No	0	4	0
1090	G.HN.31	G.HN.32	0.518088	No	No	0	1	5
1091	b.1x1	g.ntx3	0.517468	Yes	No	0	0	0
1092	G.hgh4.18	G.hgh4.19	0.488704	No	No	0	0	0
1093	5x51	5x52	0.484569	No	No	0	7	5
1094	g.ntx5	g.ntx8	0.48287	No	No	0	0	4
1095	5x77	G.hgh4.13	0.47637	No	Yes	0	0	0
1096	G.HN.26	G.HN.28	0.475185	No	No	0	0	0
1097	b.1x2	b.ntx1	0.458194	No	No	0	1	0
1098	4x51	4x52	0.431559	No	No	0	5	5
1099	E1	E1x49	0.430926	No	No	0	0	5
1100	6x23	G.H4.13	0.41875	Yes	Yes	0	4	5
1101	5x75	G.H4.16	0.40125	No	Yes	0	0	8
1102	g.h1x13	g.l1x1	0.397917	No	No	0	1	1
1103	6x42	6x46	0.395683	No	No	0	6	5
1104	1x33	1x37	0.381367	No	No	0	5	4
1105	G.S2.02	G.h1ha.01	0.368963	No	No	0	9	8
1106	b.ntx4	g.ntx8	0.366806	No	No	0	0	4
1107	8x58	8x59	0.361894	No	No	0	7	0
1108	G.HN.27	G.HN.31	0.35763	No	No	0	0	1
1109	G.HN.24	G.HN.29	0.339167	No	No	0	0	0
1110	G.HN.09	G.HN.34	0.3365	No	No	0	0	3
1111	5x83	G.H4.17	0.334593	No	No	0	0	3
1112	2x66	2x67	0.332843	No	No	0	5	5
1113	b.l21x6	b.l21x7	0.319015	No	No	0	3	5
1114	6x24	I3	0.314375	No	Yes	0	5	0
1115	4x67	4x68	0.312194	No	No	0	0	0
1116	6x22	6x23	0.30875	No	Yes	0	6	4
1117	g.h2x10	g.h2x13	0.292796	No	No	0	3	1
1118	G.HG.10	G.HG.11	0.288889	No	No	0	0	0
1119	4x40	I2	0.285556	No	No	0	6	0
1120	1x28	1x31	0.280625	No	Yes	0	0	4
1121	G.s4h3.11	G.s4h3.13	0.275849	No	No	0	9	4
1122	G.hfs2.04	G.hfs2.06	0.272377	No	No	0	6	9
1123	G.HN.10	G.HN.11	0.270397	No	No	0	4	2
1124	b.1x21	g.l1x3	0.259167	No	No	0	3	1
1125	5x82	G.H4.13	0.257259	No	Yes	0	0	5
1126	G.H4.05	G.hgh4.09	0.251389	Yes	No	0	4	0
1127	8x61	8x62	0.250556	No	No	0	0	0
1128	g.h1x1	g.ntx2	0.247704	Yes	No	0	2	0
1129	b.l4x2	g.ctx21	0.243611	Yes	No	0	4	0
1130	g.h2x6	g.h2x7	0.240269	No	No	0	2	5
1131	6x34	6x38	0.236493	No	No	0	8	7
1132	G.hgh4.12	G.hgh4.13	0.228704	No	Yes	0	0	0
1133	g.ntx5	g.ntx7	0.224306	No	No	0	0	0
1134	2x38	I2x58	0.194	No	No	0	7	0
1135	G.s4h3.09	G.s4h3.10	0.187585	No	No	0	8	4
1136	4x34	4x37	0.1865	No	No	0	0	0
1137	g.ntx1	g.ntx2	0.1825	No	No	0	0	0
1138	7x26	7x28	0.1625	No	No	0	0	0
1139	7x26	7x29	0.1625	No	No	0	0	0
1140	G.hfs2.03	G.hfs2.05	0.158667	No	No	0	9	7
1141	I1x49	I1x52	0.155704	No	No	0	6	0
1142	4x69	E2	0.152708	No	Yes	0	0	4
1143	8x56	8x60	0.140556	No	No	0	6	0
1144	4x35	I2x54	0.136481	No	No	0	0	6
1145	G.S2.01	G.h1ha.02	0.120556	No	No	0	9	4
1146	G.hfs2.05	G.hfs2.06	0.115569	No	No	0	7	9
1147	G.HN.35	b.b5x2	0.115556	No	Yes	0	4	7
1148	4x34	G.hns1.03	0.107833	No	Yes	0	0	4
1149	5x81	G.hgh4.09	0.106556	No	No	0	0	0
1150	G.H4.05	G.H4.09	0.10625	Yes	No	0	4	0
1151	5x80	I3	0.101667	No	Yes	0	0	0
1152	7x27	E2	0.0752778	No	Yes	0	0	4
1153	g.ctx12	g.ctx19	0.06375	No	No	0	6	8
1154	6x14	6x16	0.059375	No	No	0	1	3
1155	2x67	2x68	0.0586111	No	No	0	5	0
1156	1x26	1x31	0.0528125	No	Yes	0	0	4
1157	6x20	6x23	0.0484645	No	Yes	0	4	4
1158	5x86	G.hgh4.04	0.0377407	No	No	0	0	5
1159	b.lh12x5	g.h2x5	0.0328472	No	No	0	0	6
1160	8x60	8x61	0.0298519	No	No	0	0	0
1161	5x80	5x84	0.0274074	No	No	0	0	0
1162	6x18	G.H4.17	0.0259722	No	No	0	3	3
1163	6x19	6x23	0.014946	No	Yes	0	5	4
1164	G.S2.05	G.h1ha.03	0.0147222	No	No	0	6	3
1165	6x14	6x17	0.0133642	No	No	0	1	3
1166	1x27	1x31	0.0116667	No	Yes	0	0	4
1167	6x15	G.H4.13	0.00850309	No	Yes	0	5	5
1168	5x85	G.hgh4.09	0.00625926	No	No	0	0	0
1169	6x14	6x15	0.00539352	No	No	0	1	5
1170	6x21	6x24	0.00124228	No	No	0	5	5
1171	G.hfs2.02	b.l5x2	0.000825617	No	No	0	6	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.hns1.03	0.758845	4	0	4
2	G.S1.06	4.34502	4	20	8
3	G.S2.06	4.57221	5	0	3
4	G.S2.08	5.36419	4	8	3
5	G.S3.03	5.60811	6	8	4
6	G.S3.04	7.61654	4	2	7
7	G.S3.05	3.68478	4	0	6
8	G.S3.06	7.28648	5	2	7
9	G.H2.06	4.90711	7	2	8
10	G.H2.07	5.68389	5	2	9
11	G.h2s4.01	6.62886	5	2	7
12	G.s4h3.04	4.18583	6	21	8
13	G.H3.01	3.56233	6	0	9
14	G.H3.03	2.7654	4	0	8
15	G.H3.06	4.44472	4	0	9
16	G.H3.09	4.8311	7	6	9
17	G.H3.13	5.69082	5	6	8
18	G.H3.14	3.56242	4	0	5
19	G.H3.17	5.99719	7	2	4
20	G.H3.18	5.04193	4	19	5
21	G.S5.04	3.83525	4	6	8
22	G.S5.05	3.8942	6	9	9
23	G.S5.07	3.47342	5	9	8
24	G.HG.01	3.74307	4	6	9
25	G.HG.03	3.10652	4	0	9
26	G.hgh4.01	4.25816	4	0	3
27	G.hgh4.02	4.05766	5	22	6
28	G.hgh4.05	6.284	6	0	6
29	G.H4.05	3.55893	4	0	4
30	G.H4.08	3.01218	4	6	5
31	G.H4.10	8.40888	4	22	3
32	G.H4.12	5.56113	4	6	7
33	G.H4.13	1.1842	4	0	5
34	G.H4.14	5.19685	4	22	3
35	G.H4.15	6.23939	4	6	5
36	G.H4.16	2.65176	4	6	8
37	G.S6.02	5.22727	6	11	5
38	G.S6.05	5.50213	5	6	9
39	G.s6h5.01	5.16444	4	9	4
40	G.H5.03	4.61907	4	9	4
41	G.H5.08	4.60259	6	8	8
42	G.H5.13	4.25846	4	11	6
43	G.H5.17	4.36421	5	11	6
44	G.H5.20	3.51832	4	0	8
45	G.H5.25	2.81847	4	0	8
46	G.H5.26	3.23148	4	0	7
47	b.h2x1	3.73988	4	0	5
48	b.lhb1x3	2.58345	5	0	2
49	b.lhb1x6	3.64358	4	14	3
50	b.l1x3	7.79164	6	5	9
51	b.l1x6	8.1849	5	2	9
52	b.b2x1	6.32093	5	2	8
53	b.b2x5	5.96108	6	5	7
54	b.b3x3	3.46776	5	10	8
55	b.l3x1	6.88986	4	2	9
56	b.l3x2	5.14538	5	5	9
57	b.b4x3	4.06945	4	10	7
58	b.b4x6	9.22952	6	5	9
59	b.l4x2	10.4846	4	7	4
60	b.b5x2	4.73063	5	0	7
61	b.b5x3	5.75129	6	5	9
62	b.b5x5	4.98527	4	0	5
63	b.b5x7	5.49985	4	0	7
64	b.l5x1	4.14919	5	10	8
65	b.l5x5	7.48208	6	2	9
66	b.b6x5	3.87838	6	10	6
67	b.l6x5	5.86947	4	16	4
68	b.b7x1	6.09567	4	16	4
69	b.l7x4	3.36056	4	0	9
70	b.b8x3	3.11969	5	0	6
71	b.b8x4	5.23536	5	10	6
72	b.l9x3	6.60245	6	2	9
73	b.l9x6	4.35807	9	2	8
74	b.b10x5	4.22552	6	0	9
75	b.b11x4	5.40744	4	2	9
76	b.l11x2	7.90248	4	2	9
77	b.b12x6	7.62375	7	2	8
78	b.l12x1	2.98429	4	0	6
79	b.b13x7	7.59346	5	4	7
80	b.l13x3	7.04484	6	4	9
81	b.l13x6	4.33997	5	2	9
82	b.l13x7	4.30645	4	4	9
83	b.b14x3	4.3518	4	4	5
84	b.b15x1	6.47317	5	4	9
85	b.l15x1	4.91647	4	2	7
86	b.l15x2	5.20704	5	4	9
87	b.b16x4	10.0714	4	4	6
88	b.b16x6	8.2035	6	4	8
89	b.b17x5	6.60569	4	3	7
90	b.b17x7	7.66973	4	3	8
91	b.l17x3	8.37489	6	3	9
92	b.l17x6	7.37487	4	2	9
93	b.b18x3	5.10587	4	3	8
94	b.b18x5	4.80279	4	0	5
95	b.l18x1	5.93993	7	13	6
96	b.l18x2	5.48556	4	13	7
97	b.b19x2	6.49011	6	3	6
98	b.b19x4	5.77637	4	3	8
99	b.l19x1	5.18056	4	2	9
100	b.l19x2	5.90188	5	3	9
101	b.b20x4	9.81471	5	3	8
102	b.b20x6	7.26279	5	3	6
103	b.b20x7	4.50166	4	0	9
104	b.l20x2	6.65279	4	0	9
105	b.b21x1	8.23691	4	3	7
106	b.b21x5	4.70916	4	0	4
107	b.b21x7	5.51482	6	0	5
108	b.l21x2	4.46885	4	0	4
109	b.b22x5	5.24215	5	13	7
110	b.l22x5	5.95836	6	14	9
111	b.b23x1	3.45532	4	0	5
112	b.b23x6	6.54422	6	18	7
113	b.l23x1	5.79072	5	2	6
114	b.l23x2	4.3767	4	0	8
115	b.b24x4	7.0187	4	18	6
116	b.b24x6	6.21536	4	18	8
117	b.l24x3	4.38277	4	0	5
118	b.l25x3	8.18423	5	12	9
119	b.l25x6	12.3286	4	2	8
120	b.l27x1	8.90445	8	2	9
121	b.l27x2	7.78015	4	12	9
122	b.b28x3	3.8535	4	0	7
123	b.b28x4	7.3986	4	12	6
124	b.b28x6	7.83163	5	12	9
125	g.h1x1	1.29694	4	0	2
126	g.h1x8	2.15343	4	0	7
127	g.l1x4	4.89675	4	0	8
128	g.h2x11	8.99123	4	13	6
129	g.ctx3	5.38557	6	23	9
130	g.ctx6	3.39945	5	0	6
131	g.ctx14	4.91384	4	7	9
132	g.ctx15	6.44896	4	7	9
133	g.ctx16	4.55413	8	7	8
134	Lig	6.49998	13	1	0
135	1x31	0.336908	4	0	4
136	1x46	3.61875	4	1	8
137	1x50	5.8812	4	0	9
138	1x60	3.3829	5	0	7
139	I1x50	4.99839	4	25	8
140	2x42	3.91569	6	1	8
141	2x46	4.7127	4	1	9
142	2x50	6.58808	5	1	9
143	2x56	4.5429	4	1	8
144	2x57	4.10586	5	1	8
145	2x60	3.71639	5	1	7
146	E1x50	6.35116	6	15	9
147	3x24	3.28804	4	15	6
148	3x28	5.31604	4	0	6
149	3x37	3.62124	5	1	8
150	3x41	2.98061	4	0	7
151	3x42	5.30436	4	1	8
152	3x43	4.66989	4	1	8
153	3x46	3.63361	4	1	9
154	3x49	5.75554	4	1	9
155	3x50	5.62133	4	1	9
156	I2x51	3.4003	4	8	6
157	I2x53	5.78033	5	1	8
158	4x50	4.47444	4	1	9
159	E2	9.9311	15	1	4
160	5x39	4.76717	4	1	8
161	5x47	7.23013	6	1	8
162	5x50	3.03992	4	0	9
163	5x58	4.61318	6	1	9
164	5x62	3.68431	4	0	6
165	6x23	0.197728	4	0	4
166	6x44	4.27938	6	1	9
167	6x48	6.00398	8	1	8
168	6x49	3.15044	4	0	7
169	6x51	7.38879	4	1	8
170	6x52	7.63776	5	1	7
171	E3	4.04791	6	1	4
172	7x30	2.5535	4	0	7
173	7x38	6.01298	4	1	7
174	7x39	5.16359	5	1	8
175	7x42	6.35726	7	1	8
176	7x49	6.66293	4	1	9
177	7x53	4.99867	5	1	9
178	8x50	4.74643	6	25	8
179	8x54	2.8974	4	0	8
180	I3	0.635058	4	0	0
181	b.1x1	1.38325	5	0	0
182	G.hgh4.13	0.53988	4	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.l2x5	b.l4x2	15.2083	23.3584	No	Yes	0	5	4
2	b.l4x2	g.ctx15	15.3812	11.5477	Yes	Yes	7	4	9
3	b.l26x5	g.ctx15	19.4027	4.69769	No	Yes	0	5	9
4	b.l26x5	g.ctx4	23.8393	5.23559	No	No	0	5	7
5	g.ctx3	g.ctx4	23.9611	3.85555	Yes	No	0	9	7
6	g.ctx3	g.ctx5	25.2721	2.82424	Yes	No	23	9	9
7	b.lhb1x11	g.ctx5	25.5145	3.55855	No	No	0	4	9
8	b.b25x7	b.lhb1x11	25.6334	5.25028	No	No	0	7	4
9	b.b25x7	b.b28x6	25.9906	14.9296	No	Yes	0	7	9
10	b.b27x3	b.b28x6	26.6093	7.69969	No	Yes	0	8	9
11	b.b26x3	b.b27x3	32.2502	3.19144	No	No	0	6	8
12	b.b22x2	b.b26x3	34.4211	5.44047	No	No	0	8	6
13	b.b22x1	b.b22x2	34.54	2.81642	No	No	0	8	8
14	b.b22x1	b.l25x6	34.5926	3.99682	No	Yes	2	8	8
15	b.l25x6	b.l27x1	46.7205	21.0967	Yes	Yes	2	8	9
16	b.l1x6	b.l27x1	29.7304	21.475	Yes	Yes	2	9	9
17	b.l1x6	b.l3x1	36.0386	5.14253	Yes	Yes	2	9	9
18	b.l3x1	b.l5x5	72.1277	5.63259	Yes	Yes	2	9	9
19	b.b2x1	b.l27x1	29.7304	6.22498	Yes	Yes	2	8	9
20	b.b2x1	b.l3x1	35.9782	13.284	Yes	Yes	2	8	9
21	G.h2s4.01	b.l5x5	68.7579	10.779	Yes	Yes	2	7	9
22	G.H2.07	G.h2s4.01	75.9241	3.1843	Yes	Yes	2	9	7
23	G.H2.04	G.H2.07	96.1541	5.57775	No	Yes	0	9	9
24	G.H2.04	G.H3.08	96.2349	4.28399	No	No	0	9	5
25	G.H3.08	G.S4.04	96.2793	5.01968	No	No	0	5	7
26	G.H3.09	G.S4.04	95.5433	9.09502	Yes	No	0	9	7
27	G.H3.09	G.S5.04	94.707	3.23949	Yes	Yes	6	9	8
28	G.S5.04	G.S5.06	96.2899	3.80545	Yes	No	0	8	9
29	G.S5.06	G.S6.05	98.113	5.77649	No	Yes	0	9	9
30	G.HG.01	G.S6.05	98.8446	5.9573	Yes	Yes	6	9	9
31	G.HG.01	G.s6h5.02	99.3709	2.73756	Yes	No	0	9	9
32	G.HG.02	G.s6h5.02	99.4117	3.38114	No	No	0	5	9
33	G.HG.02	G.HG.03	99.4523	2.9221	No	Yes	0	5	9
34	G.HG.03	G.s5hg.01	99.5743	4.09607	Yes	No	0	9	9
35	G.S5.07	G.s5hg.01	100	3.65849	Yes	No	0	8	9
36	G.H1.04	G.S5.07	50.0208	3.25453	No	Yes	9	9	8
37	G.H1.04	G.S5.05	50.1162	3.66666	No	Yes	9	9	9
38	G.H5.07	G.S5.05	20.9655	3.05281	No	Yes	0	3	9
39	G.H5.07	G.S4.03	20.9438	2.92381	No	No	0	3	8
40	G.S1.04	G.S4.03	20.4654	3.70068	No	No	0	7	8
41	G.S1.04	G.S3.03	20.2496	3.1747	No	Yes	0	7	4
42	G.S5.07	G.s6h5.01	50.1374	5.21452	Yes	Yes	9	8	4
43	G.S5.05	G.s6h5.01	50.1435	5.02056	Yes	Yes	9	9	4
44	G.H3.17	b.l23x1	29.8118	2.92708	Yes	Yes	2	4	6
45	G.H5.08	G.S3.03	20.0204	3.00628	Yes	Yes	8	8	4
46	G.H2.06	b.l9x6	19.0022	3.04093	Yes	Yes	2	8	8
47	G.H2.06	b.l19x1	18.6941	2.97465	Yes	Yes	2	8	9
48	G.H5.10	G.S6.02	79.4053	7.98325	No	Yes	0	4	5
49	G.H5.10	G.S5.03	39.7271	6.13654	No	No	0	4	6
50	G.S5.03	G.S5.05	39.7653	3.23382	No	Yes	0	6	9
51	G.H5.10	G.S6.04	39.7246	4.99844	No	No	0	4	5
52	G.S5.05	G.S6.04	39.7627	4.19045	Yes	No	0	9	5
53	G.H5.13	G.S6.02	39.4893	6.71061	Yes	Yes	11	6	5
54	G.H5.17	G.S6.02	39.3701	4.08213	Yes	Yes	11	6	5
55	G.H5.08	G.H5.12	19.8324	3.51344	Yes	No	8	8	8
56	5x68	G.H5.13	39.278	4.99547	No	Yes	11	7	6
57	5x68	G.H5.16	78.4366	4.90834	No	No	0	7	7
58	G.H5.16	I2x50	78.3238	3.37908	No	No	0	7	8
59	5x68	G.H5.17	39.2717	5.24077	No	Yes	11	7	6
60	G.H5.12	I2x50	19.8303	2.86453	No	No	0	8	8
61	G.H5.15	I2x50	98.0002	2.69287	No	No	0	7	8
62	G.H5.15	G.H5.19	97.5826	3.37832	No	No	0	7	4
63	G.H5.19	I2x53	97.2907	3.0592	No	Yes	1	4	8
64	5x58	6x37	10.0701	5.75837	Yes	No	0	9	8
65	3x47	5x57	32.8028	3.83164	No	No	0	9	7
66	3x48	5x57	35.3943	2.90794	No	No	0	6	7
67	3x48	3x52	35.5404	3.61837	No	No	0	6	5
68	3x52	I2x53	35.6873	5.62635	No	Yes	0	5	8
69	2x42	3x46	49.0748	3.34081	Yes	Yes	1	8	9
70	2x42	3x49	60.1871	6.09429	Yes	Yes	1	8	9
71	3x49	I2x53	60.4561	7.26101	Yes	Yes	1	9	8
72	b.l17x5	b.l19x1	18.6579	3.45596	No	Yes	0	6	9
73	b.l17x5	b.l19x2	18.5922	4.24668	No	Yes	0	6	9
74	b.b20x4	b.b20x6	10.5467	3.72159	Yes	Yes	3	8	6
75	b.b17x7	b.b20x6	12.7653	9.223	Yes	Yes	3	8	6
76	b.l17x3	b.l19x2	12.7827	3.90949	Yes	Yes	3	9	9
77	b.h2x1	b.h2x5	10.3722	3.34572	Yes	No	0	5	5
78	b.b21x5	b.h2x1	11.8872	5.90838	Yes	Yes	0	4	5
79	b.l2x3	b.l2x5	12.6537	3.45437	No	No	0	8	5
80	b.b3x1	b.l2x3	12.5301	5.48943	No	No	0	5	8
81	b.b3x1	b.b6x5	12.4064	3.75763	No	Yes	0	5	6
82	b.b21x5	b.b21x7	15.633	7.73708	Yes	Yes	0	4	5
83	b.b21x7	b.b23x2	10.1637	5.17851	Yes	No	0	5	6
84	b.b21x7	b.b24x6	32.3287	9.35192	Yes	Yes	0	5	8
85	b.b23x6	b.b24x6	33.1324	6.3607	Yes	Yes	18	7	8
86	b.l21x7	b.l23x1	41.0279	4.1827	No	Yes	0	5	6
87	b.b23x6	b.l23x2	38.1552	3.86048	Yes	Yes	0	7	8
88	6x48	Lig	44.7578	3.93769	Yes	Yes	1	8	0
89	6x44	6x48	46.4959	4.97529	Yes	Yes	1	9	8
90	3x43	6x44	26.8008	2.84738	Yes	Yes	1	8	9
91	3x43	7x53	41.4821	6.92763	Yes	Yes	1	8	9
92	3x46	7x53	42.6102	4.85778	Yes	Yes	1	9	9
93	5x54	6x44	26.869	5.42648	No	Yes	1	9	9
94	3x47	5x54	26.9279	4.62588	No	No	1	9	9
95	2x45	4x46	10.3876	7.50427	No	No	0	9	8
96	2x42	4x46	10.5356	3.33742	Yes	No	0	8	8
97	7x42	Lig	18.2445	5.78002	Yes	Yes	1	8	0
98	2x46	2x50	13.9675	3.73558	Yes	Yes	1	9	9
99	2x50	7x46	10.2036	8.96853	Yes	No	0	9	9
100	2x56	3x28	18.6184	3.39971	Yes	Yes	0	8	6
101	2x60	3x28	10.6663	4.3484	Yes	Yes	0	7	6
102	3x28	E1x50	22.7141	5.98272	Yes	Yes	0	6	9
103	E1x51	E1x52	11.2163	3.29508	No	No	0	5	7
104	E1x50	E1x52	12.8587	9.33951	Yes	No	15	9	7
105	G.H2.07	b.l9x6	19.9178	4.94486	Yes	Yes	2	9	8
106	G.H3.17	b.l27x1	12.2779	3.1948	Yes	Yes	2	4	9
107	b.l21x7	b.l23x2	40.1865	6.13644	No	Yes	0	5	8
108	b.l23x1	b.l25x6	12.037	15.7221	Yes	Yes	2	6	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
3x32	Lig	12.3911	1	No	Yes	8	0	1	0
3x33	Lig	11.1621	0	No	Yes	8	0	1	0
3x36	Lig	7.8178	1	No	Yes	7	0	1	0
3x37	Lig	2.86032	1	Yes	Yes	8	0	1	0
E2x52	Lig	3.53891	1	No	Yes	6	0	1	0
5x43	Lig	3.81639	0	No	Yes	8	0	1	0
5x461	Lig	3.43582	1	No	Yes	8	0	1	0
6x48	Lig	3.93769	1	Yes	Yes	8	0	1	0
6x51	Lig	12.5075	1	Yes	Yes	8	0	1	0
6x52	Lig	5.56849	1	Yes	Yes	7	0	1	0
7x38	Lig	8.08708	1	Yes	Yes	7	0	1	0
7x42	Lig	5.78002	1	Yes	Yes	8	0	1	0
2x56	3x32	7.97594	1	Yes	No	8	8	2	1
2x56	7x42	3.88703	1	Yes	Yes	8	8	2	1
2x57	7x39	3.22795	1	Yes	Yes	8	8	2	2
2x57	7x42	6.46597	1	Yes	Yes	8	8	2	1
2x60	7x39	3.19714	1	Yes	Yes	7	8	2	2
2x60	7x42	4.85844	1	Yes	Yes	7	8	2	1
3x29	E2x52	3.31722	0	No	No	7	6	2	1
3x32	7x42	9.00539	1	No	Yes	8	8	1	1
3x33	4x57	7.03242	0	No	No	8	8	1	2
3x36	6x48	4.5365	1	No	Yes	7	8	1	1
3x37	3x41	2.8639	1	Yes	Yes	8	7	1	2
3x37	4x53	4.56707	1	Yes	No	8	8	1	2
3x37	5x461	5.41446	1	Yes	No	8	8	1	1
3x40	6x44	3.59117	1	No	Yes	8	9	2	2
3x40	6x48	8.03967	1	No	Yes	8	8	2	1
E2	E2	48.4232	1	Yes	Yes	4	4	2	2
5x39	E2	6.39511	1	Yes	Yes	8	4	2	2
5x39	5x43	5.67246	1	Yes	No	8	8	2	1
5x44	6x52	3.61335	0	No	Yes	7	7	2	1
5x47	6x44	4.84897	1	Yes	Yes	8	9	2	2
5x47	6x48	3.74614	1	Yes	Yes	8	8	2	1
5x47	6x52	18.6109	1	Yes	Yes	8	7	2	1
6x44	6x48	4.97529	1	Yes	Yes	9	8	2	1
6x48	6x52	5.04786	1	Yes	Yes	8	7	1	1
6x48	7x41	8.00332	1	Yes	No	8	8	1	2
6x48	7x45	9.74538	1	Yes	No	8	9	1	2
6x51	6x52	5.34818	1	Yes	Yes	8	7	1	1
6x51	6x55	6.07262	1	Yes	No	8	8	1	1
6x51	7x38	5.62684	1	Yes	Yes	8	7	1	1
7x38	7x42	6.78735	1	Yes	Yes	7	8	1	1
7x39	7x42	7.71662	1	Yes	Yes	8	8	2	1
6x55	Lig	3.59644	1	No	Yes	8	0	1	0
E2	E2x52	5.76779	1	Yes	No	4	6	2	1
5x40	6x55	3.52373	0	No	No	7	8	2	1
2x60	7x38	3.55067	1	Yes	Yes	7	7	2	1
3x37	4x56	2.40046	1	Yes	No	8	8	1	2

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
100.00	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
92.86	Single	3D4S	Timolol	3D4S-β₂-Timolol
92.86	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
92.31	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
92.31	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
92.31	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
92.31	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
92.31	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
92.31	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
92.31	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
92.31	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
92.31	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
92.31	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
92.31	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
92.31	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
92.31	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
92.31	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
86.67	Single	8S2T	Isoprenaline	8S2T-β₁-Isoprenaline-chim(NtGi1-Gs)/β1/γ2
85.71	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
85.71	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
85.71	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
85.71	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
85.71	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
85.71	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
85.71	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
84.62	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
84.62	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
84.62	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
84.62	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
84.62	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
84.62	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
84.62	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
84.62	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
84.62	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
84.62	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
84.62	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
84.62	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
84.62	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
84.62	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
84.62	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
84.62	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
84.62	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
84.62	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
84.62	Single	9PLN	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLN-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine
84.62	Single	9PLO	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLO-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine-Go/β1/γ2
84.62	Single	9PQD	(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole	9PQD-α_2a-(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole
84.62	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
84.62	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
84.62	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
84.62	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
84.62	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
84.62	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
84.62	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
84.62	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
84.62	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
84.62	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
84.62	Consensus	dopamine_on_gp	Orthosteric Ligand	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
80.00	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
80.00	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
80.00	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
80.00	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
80.00	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
78.57	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
78.57	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
78.57	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-Cmpd-15
78.57	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
78.57	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
78.57	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
78.57	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
78.57	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
78.57	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
78.57	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
78.57	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
78.57	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
78.57	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
78.57	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
78.57	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
78.57	Single	9DYD	Asenapine	9DYD-5-HT_1A-Asenapine-Go/β1/γ2
78.57	Single	9DYF	Asenapine	9DYF-5-HT_1A-Asenapine-Gi1/β1/γ2
78.57	Single	9K07	DSO-5a	9K07-BB₃-DSO-5a-chim(NtGi2L-Gs-CtGq)/β1/γ2
78.57	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
78.57	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
78.57	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
78.57	Consensus	adrenergic_on_gp	Orthosteric Ligand	alpha_on_gp beta_on_gp
78.57	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
78.57	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
78.57	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
78.57	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
76.92	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
76.92	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
76.92	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
76.92	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
76.92	Single	6PS5	S-Propranolol	6PS5-β₂-S-Propranolol
76.92	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
76.92	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
76.92	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
76.92	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
76.92	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/β1/γ2
76.92	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
76.92	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
76.92	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8GG7	Constrained Epinephrine	8GG7-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8GGL	Constrained Epinephrine	8GGL-β₂-Constrained Epinephrine
76.92	Single	8GGM	Constrained Epinephrine	8GGM-β₂-Constrained Epinephrine
76.92	Single	8GGP	Constrained Epinephrine	8GGP-β₂-Constrained Epinephrine
76.92	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
76.92	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
76.92	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
76.92	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
76.92	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
76.92	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
76.92	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
76.92	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
76.92	Single	8UNL	Constrained Epinephrine	8UNL-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNO	Constrained Epinephrine	8UNO-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
76.92	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
76.92	Single	9AS5	Mescaline	9AS5-5-HT_2A-Mescaline
76.92	Single	9AS6	Mescaline	9AS6-5-HT_2A-Mescaline-chim(NtGi1-Gs-CtGq)/β1/γ2
76.92	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
76.92	Consensus	5ht_on_gp	Orthosteric Ligand	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
76.92	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
76.92	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
76.92	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
76.92	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
76.92	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
76.92	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
76.47	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
75.00	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
75.00	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
75.00	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
75.00	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
75.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
73.33	Single	2YDV	NECA	2YDV-A_2A-NECA
73.33	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
73.33	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
73.33	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
73.33	Single	5G53	NECA	5G53-A_2A-NECA-Gs
73.33	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
73.33	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
73.33	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
73.33	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
73.33	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
73.33	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
73.33	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
73.33	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
73.33	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
73.33	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
73.33	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
73.33	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
73.33	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
73.33	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
71.43	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
71.43	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
71.43	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
71.43	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
71.43	Single	6PRZ	S-Alprenolol	6PRZ-β₂-S-Alprenolol
71.43	Single	6PS1	Timolol	6PS1-β₂-Timolol
71.43	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
71.43	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
71.43	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
71.43	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
71.43	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
71.43	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
71.43	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
71.43	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
71.43	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
71.43	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
71.43	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
71.43	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
71.43	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
71.43	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
71.43	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
71.43	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
71.43	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
71.43	Single	9AS1	DMT	9AS1-5-HT_2A-DMT
71.43	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
71.43	Single	9JEA	Atropine	9JEA-M₁-Atropine
71.43	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
71.43	Consensus	5ht5a_on	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
71.43	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
71.43	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
71.43	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
71.43	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
71.43	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
70.59	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
70.59	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
69.23	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
69.23	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
69.23	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
69.23	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
69.23	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
69.23	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
69.23	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
69.23	Single	8GGW	Constrained Epinephrine	8GGW-β₂-Constrained Epinephrine
69.23	Single	8GGZ	Constrained Epinephrine	8GGZ-β₂-Constrained Epinephrine
69.23	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
69.23	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
69.23	Single	8UNS	Constrained Epinephrine	8UNS-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8UNT	Constrained Epinephrine	8UNT-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
69.23	Single	8YUT	Amthamine	8YUT-H₂-Amthamine-Gs/β1/γ2
69.23	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
69.23	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
69.23	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
69.23	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
69.23	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
69.23	Consensus	gs_5ht	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2 7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2 7XT8-5-HT₄-Serotonin-Gs/β1/γ2
69.23	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
68.75	Single	4LDE	BI167107	4LDE-β₂-BI167107
68.75	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
68.75	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
68.75	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
68.75	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
68.75	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
68.75	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
68.75	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
68.75	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
68.75	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
68.75	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
68.75	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
68.75	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
68.75	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
68.75	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
68.75	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
68.75	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
68.75	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
66.67	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
66.67	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
66.67	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
66.67	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
66.67	Single	6E67	BI167107	6E67-β₂-BI167107-Gs(CT)
66.67	Single	6PS6	Timolol	6PS6-β₂-Timolol
66.67	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
66.67	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
66.67	Single	9ARY	Serotonin	9ARY-5-HT_2A-Serotonin-chim(NtGi1-Gs-CtGq)/β1/γ2
66.67	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
66.67	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
66.67	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
66.67	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
66.67	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
66.67	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
66.67	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
66.67	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
66.67	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
64.71	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
64.71	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
64.71	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
64.71	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
64.71	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
64.71	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
64.71	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
64.71	Single	9AS0	2-bromo-LSD	9AS0-5-HT_2A-2-bromo-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
64.71	Single	9DYE	Buspirone	9DYE-5-HT_1A-Buspirone-Go/β1/γ2
64.71	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
64.71	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
64.29	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
64.29	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
64.29	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
64.29	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
64.29	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
64.29	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
64.29	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
64.29	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
64.29	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
64.29	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
64.29	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
64.29	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
64.29	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
64.29	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
64.29	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
64.29	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
64.29	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
64.29	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
64.29	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
64.29	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
64.29	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
64.29	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
64.29	Single	9AS3	LSD	9AS3-5-HT_2A-LSD
64.29	Single	9AS4	LSD	9AS4-5-HT_2A-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
64.29	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
64.29	Single	9LRD	Histamine	9LRD-H₁-Histamine-Gi1/β1/γ2
64.29	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
62.50	Single	3P0G	BI167107	3P0G-β₂-BI167107
62.50	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
62.50	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
62.50	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
62.50	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
62.50	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
62.50	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
62.50	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
62.50	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
62.50	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
62.50	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
62.50	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
62.50	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
62.50	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
62.50	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
62.50	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
62.50	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
62.50	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
62.50	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
62.50	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
62.50	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
61.54	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
61.54	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
61.54	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
61.54	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
61.54	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/β1/γ2
61.54	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/β1/γ2
61.54	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
61.54	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
61.54	Single	9AS2	DMT	9AS2-5-HT_2A-DMT-chim(NtGi1-Gs-CtGq)/β1/γ2
61.54	Single	9IJE	Epinephrine	9IJE-β₃-Epinephrine-chim(NtGi1-Gs)/β1/γ2
61.54	Single	9IXJ	Histamine	9IXJ-H₂-Histamine-Gs/β1/γ2
61.54	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
61.54	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
61.11	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
61.11	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
61.11	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
60.00	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
60.00	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
60.00	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
60.00	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
60.00	Single	4QKX	35V	4QKX-β₂-35V
60.00	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
60.00	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
60.00	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
60.00	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
60.00	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
60.00	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
60.00	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
60.00	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
60.00	Single	7BU7	BI167107	7BU7-β₁-BI167107
60.00	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
60.00	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
60.00	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
60.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
60.00	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
60.00	Single	8JXR	LSD	8JXR-D₁-LSD
60.00	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-Gi1/β1/γ1
60.00	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
60.00	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
60.00	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
60.00	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
60.00	Consensus	histamine_off	Orthosteric Ligand	h1_off
60.00	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
60.00	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
58.82	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
58.82	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
58.82	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
58.82	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
58.82	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
58.82	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
58.82	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
58.82	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
58.82	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
58.82	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
58.82	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
58.82	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
58.82	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
57.89	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
57.89	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
57.89	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-Gi1/β1/γ1
57.89	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
57.89	Single	9M4T	Silodosin	9M4T-Alpha1A-Silodosin
57.89	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
57.14	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
57.14	Single	6OBA	S-Alprenolol	6OBA-β₂-S-Alprenolol-GTPL11074
57.14	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
57.14	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
57.14	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
57.14	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
57.14	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
57.14	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
57.14	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
57.14	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
57.14	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
57.14	Single	9LRB	Histamine	9LRB-H₁-Histamine-Gs/β1/γ2
57.14	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
57.14	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
57.14	Consensus	sensory_offon	Orthosteric Ligand	sensory_off sensory_on
57.14	Consensus	sensory_offon_gp	Orthosteric Ligand	sensory_on_gp sensory_on
56.25	Single	5C1M	BU72	5C1M-μ-BU72
56.25	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
56.25	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
56.25	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
56.25	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
56.25	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
56.25	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
56.25	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
56.25	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
56.25	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
56.25	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
56.25	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
56.25	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
56.25	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
56.25	Single	9ARZ	2-bromo-LSD	9ARZ-5-HT_2A-2-bromo-LSD
56.25	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
56.25	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go/β1/γ2
56.25	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go/β1/γ2
56.25	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
55.56	Single	5X93	K-8794	5X93-ET_B-K-8794
55.56	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
55.56	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
55.56	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
55.56	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
55.56	Single	9CGJ	C6-Quino	9CGJ-δ-C6-Quino-Gi1/β1/γ2
55.56	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
55.56	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
55.56	Consensus	endothelin_off	Orthosteric Ligand	etb_off
55.56	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
55.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
53.85	Single	6FUF	All-trans-Retinal	6FUF-Rhodopsin-All-trans-Retinal-Go
53.85	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/β1/γ2
53.85	Single	8GH1	Constrained Epinephrine	8GH1-β₂-Constrained Epinephrine
53.85	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
53.85	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
53.85	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
53.85	Consensus	opsins_on_gp	Orthosteric Ligand	rhodopsin_on_gp opsin1lw_on_gp
53.85	Consensus	rhodopsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
53.85	Consensus	sensory_on_gp	Orthosteric Ligand	opsins_on_gp
53.33	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
53.33	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
53.33	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
53.33	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
53.33	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
53.33	Single	6TPG	EMPA	6TPG-OX₂-EMPA
53.33	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
53.33	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
53.33	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
53.33	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
53.33	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.33	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
53.33	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
53.33	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
53.33	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
53.33	Single	9ARX	Serotonin	9ARX-5-HT_2A-Serotonin
52.94	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
52.94	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
52.94	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
52.94	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
52.94	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
52.94	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
52.94	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
52.94	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
52.94	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
52.94	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
52.94	Single	8E0G	BU72	8E0G-μ-BU72
52.94	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
52.94	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
52.94	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
52.94	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
52.94	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
52.94	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
52.94	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
52.94	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
52.94	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
52.94	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
52.94	Single	9I54	A1IZV	9I54-D₁-A1IZV-Gs/β1/γ2
52.94	Consensus	a2_on	Orthosteric Ligand	a2b_on
52.94	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
52.94	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
52.94	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
52.94	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
52.94	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
52.94	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
52.94	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
52.63	Single	6PT3	DPI-287	6PT3-δ-DPI-287
52.63	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
52.63	Single	9CGK	C5-Quino	9CGK-δ-C5-Quino-Gi1/β1/γ2
52.63	Single	9MD1	Buspirone	9MD1-5-HT_1A-Buspirone-Gz/β1/γ2
52.38	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
50.00	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
50.00	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
50.00	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
50.00	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
50.00	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
50.00	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
50.00	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
50.00	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
50.00	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
50.00	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
50.00	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
50.00	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
50.00	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
50.00	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
50.00	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
50.00	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
50.00	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
50.00	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
50.00	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/β1/γ2
50.00	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
50.00	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
50.00	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
50.00	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
50.00	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
50.00	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
50.00	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
50.00	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
50.00	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
50.00	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
50.00	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
50.00	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
50.00	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
50.00	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
50.00	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
50.00	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
50.00	Single	8T1W	CVN424	8T1W-GPR6-CVN424
50.00	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
50.00	Single	8UO4	Constrained Epinephrine	8UO4-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
50.00	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
50.00	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
50.00	Single	8YN2	Histamine	8YN2-H₁-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
50.00	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
50.00	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
50.00	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
50.00	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
50.00	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
50.00	Single	9BUY	LM189	9BUY-β₂-LM189-Gi1/β1/γ2
50.00	Single	9GL2	Befiradol	9GL2-5-HT_1A-Befiradol-Gs/β1/γ2
50.00	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
50.00	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
50.00	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
50.00	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
50.00	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
50.00	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
50.00	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
50.00	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
50.00	Consensus	gi_orexin	Orthosteric Ligand	7SQO-OX₂-TAK-925-Gi1/β1/γ2
50.00	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
47.62	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
47.62	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
47.37	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
47.37	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
47.37	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
47.37	Single	7EZC	UKA	7EZC-A_2A-UKA
47.37	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
47.37	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
47.37	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
47.37	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-chim(NtGi2L-Gs-CtGq)/β1/γ2
47.37	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
47.37	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
47.37	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
47.06	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
47.06	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
47.06	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
47.06	Single	5WQC	EMPA	5WQC-OX₂-EMPA
47.06	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
47.06	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
47.06	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
47.06	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
47.06	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
47.06	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
47.06	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
47.06	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
47.06	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
47.06	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
47.06	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
47.06	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
47.06	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
47.06	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
47.06	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
47.06	Single	9I52	A1IZU	9I52-D₁-A1IZU-Gs/β1/γ2
47.06	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
47.06	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
47.06	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
47.06	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
47.06	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
46.67	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
46.67	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
46.67	Single	6AKX	A4R	6AKX-CCR5-A4R
46.67	Single	6B73	MP1104	6B73-κ-MP1104
46.67	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
46.67	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
46.67	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
46.67	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2
46.67	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
46.67	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
46.67	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
46.67	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
46.67	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
46.67	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
46.67	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
46.67	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
46.67	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
46.67	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
46.67	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
46.67	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
46.67	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
46.67	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
46.67	Consensus	5ht2_on_gp	Orthosteric Ligand	5ht2b_on_gp
46.67	Consensus	5ht2b_on_gp	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
46.67	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
46.67	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
46.67	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
46.67	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
46.67	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
46.15	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
46.15	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.15	Single	8GEI	Constrained Epinephrine	8GEI-β₂-Constrained Epinephrine-Gs/β1/γ2
46.15	Single	8IWM	2-Phenylethylamine	8IWM-TA9-2-Phenylethylamine
46.15	Single	8WC5	Tetramethylammonium Ion	8WC5-TA1-Tetramethylammonium Ion-chim(NtGi1-Gs)/β1/γ2
46.15	Single	9CHU	Noradrenaline	9CHU-β₂-Noradrenaline
46.15	Consensus	gs_histamine	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
46.15	Consensus	h2_on	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
46.15	Consensus	opsins_on	Orthosteric Ligand	rhodopsin_on opsin1lw_on
46.15	Consensus	sensory_on	Orthosteric Ligand	opsins_on
45.45	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
45.45	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
45.00	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
45.00	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
45.00	Single	8Y72	Peptide	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
45.00	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
45.00	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
44.44	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
44.44	Single	4DJH	JDTic	4DJH-κ-JDTic
44.44	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
44.44	Single	6E59	L-760735	6E59-NK₁-L-760735
44.44	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
44.44	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
44.44	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
44.44	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
44.44	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
44.44	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
44.44	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
44.44	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
44.44	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
44.44	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
44.44	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
44.44	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
44.44	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
44.44	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
44.44	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
44.44	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
43.75	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
43.75	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
43.75	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
43.75	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
43.75	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
43.75	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
43.75	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
43.75	Single	6VI4	JDTic	6VI4-κ-JDTic
43.75	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
43.75	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
43.75	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
43.75	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
43.75	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
43.75	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
43.75	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
43.75	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
43.75	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
43.75	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
43.75	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
43.75	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
43.75	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
43.75	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
43.75	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
43.75	Consensus	sensory_off	Orthosteric Ligand	opsins_off
42.86	Single	3PQR	All-trans-Retinal	3PQR-Rhodopsin-All-trans-Retinal-Gt(CT)
42.86	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
42.86	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
42.86	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
42.86	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
42.86	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
42.86	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
42.86	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
42.86	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
42.86	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
42.86	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
42.86	Single	9LRC	Histamine	9LRC-H₄-Histamine
42.86	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
42.86	Consensus	5ht2_on	Orthosteric Ligand	5ht2b_on
42.86	Consensus	5ht2b_on	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
42.86	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
42.86	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
42.86	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
42.11	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
42.11	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
42.11	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
42.11	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
42.11	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
42.11	Single	8JWY	2-118	8JWY-A_2A-2-118
42.11	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
42.11	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
42.11	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
42.11	Single	9M4Q	Doxazosin	9M4Q-Alpha1A-Doxazosin
42.11	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
42.11	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
42.11	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
42.11	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
42.11	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
41.18	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
41.18	Single	5DHG	C-35	5DHG-NOP-C-35
41.18	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
41.18	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
41.18	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
41.18	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
41.18	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
41.18	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
41.18	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
41.18	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
41.18	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
41.18	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
41.18	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
41.18	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
41.18	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
41.18	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
41.18	Single	9KFJ	PubChem 138319674	9KFJ-RXFP3-PubChem 138319674-Gi2/β1/γ2
41.18	Consensus	a3_on	Orthosteric Ligand	a3a_on
41.18	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
41.18	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
41.18	Consensus	blt_on	Orthosteric Ligand	blt1_on
41.18	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
41.18	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
41.18	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
41.18	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
40.00	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
40.00	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
40.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
40.00	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
40.00	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
40.00	Single	6HLL	CP99994	6HLL-NK₁-CP99994
40.00	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
40.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
40.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
40.00	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
40.00	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
40.00	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
40.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
40.00	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
40.00	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
40.00	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
40.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
40.00	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
40.00	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
40.00	Single	9AS7	Psilocin	9AS7-5-HT_2A-Psilocin
40.00	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
40.00	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
40.00	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
40.00	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
39.13	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
39.13	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
39.13	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
38.89	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
38.89	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
38.89	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
38.89	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
38.89	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
38.89	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
38.89	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
38.89	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
38.89	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
38.89	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
38.89	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
38.89	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
38.89	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
38.89	Single	7W41	PD176252	7W41-BB₂-PD176252
38.89	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
38.89	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
38.89	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
38.89	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
38.89	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
38.89	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
38.89	Single	9HAP	Tolvaptan	9HAP-V₂-Tolvaptan
38.89	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
38.89	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
38.89	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
38.89	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
38.46	Single	3PXO	All-trans-Retinal	3PXO-Rhodopsin-All-trans-Retinal
38.46	Single	5DYS	All-trans-Retinal	5DYS-Rhodopsin-All-trans-Retinal
38.46	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
38.46	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
38.10	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
38.10	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
38.10	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
38.10	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
38.10	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
38.10	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
37.50	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
37.50	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
37.50	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
37.50	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
37.50	Single	5WS3	EMPA	5WS3-OX₂-EMPA
37.50	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
37.50	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
37.50	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
37.50	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
37.50	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
37.50	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
37.50	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
37.50	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
37.50	Single	8A6C	All-trans-Retinal	8A6C-Rhodopsin-All-trans-Retinal
37.50	Single	8A6D	All-trans-Retinal	8A6D-Rhodopsin-All-trans-Retinal
37.50	Single	8A6E	All-trans-Retinal	8A6E-Rhodopsin-All-trans-Retinal
37.50	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
37.50	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
37.50	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
37.50	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
37.50	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
37.50	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
37.50	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
37.50	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
37.50	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
37.50	Single	9H2X	A1IR1	9H2X-A_2A-A1IR1-Na
37.50	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
37.50	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
37.50	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
37.50	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
37.50	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
36.84	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
36.84	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
36.84	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
36.84	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
36.84	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
36.84	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
36.84	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
36.84	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
36.84	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
36.84	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
36.36	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
36.36	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
36.36	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
36.36	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
36.36	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
36.00	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
36.00	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
36.00	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
35.71	Single	2HPY	All-trans-Retinal	2HPY-Rhodopsin-All-trans-Retinal
35.71	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
35.71	Single	7MTB	All-trans-Retinal	7MTB-Rhodopsin-All-trans-Retinal-GRK1
35.71	Single	9EE9	Adenosine	9EE9-A_2A-Adenosine-Gs/β1/γ2
35.71	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
35.71	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
35.71	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
35.71	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
35.71	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
35.29	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
35.29	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
35.29	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
35.29	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
35.29	Single	6IQL	L745870	6IQL-D₄-L745870
35.29	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
35.29	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
35.29	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
35.29	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
35.29	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
35.29	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
35.29	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
35.29	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
35.29	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
35.29	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
35.29	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
35.29	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
35.29	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
35.29	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
35.29	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
35.29	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
35.29	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
35.29	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
35.29	Consensus	a2_off	Orthosteric Ligand	a2a_off
35.29	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
35.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
35.00	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
35.00	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
35.00	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
35.00	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
35.00	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
35.00	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
35.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
35.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
35.00	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
35.00	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
35.00	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
35.00	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
35.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
35.00	Single	8JD3	JNJ-40411813	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
35.00	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
35.00	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
35.00	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
35.00	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
35.00	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
35.00	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
35.00	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
35.00	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
35.00	Consensus	orexin_on	Orthosteric Ligand	ox2_on
35.00	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
35.00	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
35.00	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
34.78	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
34.78	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
34.78	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
34.78	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
34.78	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
34.62	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
33.33	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
33.33	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
33.33	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
33.33	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
33.33	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
33.33	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
33.33	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
33.33	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
33.33	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
33.33	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
33.33	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
33.33	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
33.33	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
33.33	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
33.33	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
33.33	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
33.33	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
33.33	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
33.33	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
33.33	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
33.33	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
33.33	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
33.33	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
33.33	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
33.33	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
33.33	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
33.33	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
33.33	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
33.33	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
33.33	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
33.33	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
33.33	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
33.33	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
33.33	Single	8ZWG	JR14a	8ZWG-C3a_B-JR14a-Gi1/β1/γ2
33.33	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
33.33	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
33.33	Single	9H37	A1IR0	9H37-A_2A-A1IR0-Na
33.33	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
33.33	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
33.33	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
33.33	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
33.33	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
33.33	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
33.33	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
33.33	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
33.33	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
33.33	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
33.33	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
33.33	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
33.33	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
33.33	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
33.33	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
33.33	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
33.33	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
32.14	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
32.00	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
32.00	Single	8ZBI	Somatostatin-14	8ZBI-SST3-Somatostatin-14-Gi1/β1/γ2
32.00	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
32.00	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
32.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
32.00	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
32.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
32.00	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
32.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
32.00	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
32.00	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
31.82	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
31.82	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
31.82	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
31.82	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
31.82	Single	9IPV	JR14a	9IPV-C3a_B-JR14a-Gi1/β1/γ2
31.82	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
31.82	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
31.82	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
31.82	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
31.82	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
31.58	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
31.58	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
31.58	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
31.58	Single	5N2S	PSB36	5N2S-A₁-PSB36
31.58	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
31.58	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
31.58	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
31.58	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
31.58	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
31.58	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
31.58	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
31.58	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
31.58	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
31.58	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
31.58	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
31.58	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
31.58	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
31.58	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
31.58	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
31.58	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
31.58	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
31.58	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
31.58	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
31.58	Single	9EHS	LUF7602	9EHS-A_3A-LUF7602
31.58	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
31.58	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
31.58	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
31.25	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
31.25	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
31.25	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
31.25	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
31.25	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
31.25	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
31.25	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
31.25	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
31.25	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
31.25	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
31.25	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
30.77	Single	4A4M	All-trans-Retinal	4A4M-Rhodopsin-All-trans-Retinal-Gt(CT)
30.77	Single	5EN0	All-trans-Retinal	5EN0-Rhodopsin-All-trans-Retinal-Gt(CT)
30.77	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
30.77	Single	8GEJ	Constrained Epinephrine	8GEJ-β₂-Constrained Epinephrine-Gs/β1/γ2
30.77	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
30.77	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
30.43	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
30.43	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
30.43	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
30.43	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
30.43	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
30.43	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
30.43	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
30.43	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
30.43	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
30.43	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
30.00	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
30.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
30.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
30.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
30.00	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
30.00	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
30.00	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
30.00	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
30.00	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
30.00	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
30.00	Single	8X0F	VU0424465	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
30.00	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
30.00	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
30.00	Single	8Y73	Peptide	8Y73-μ-Peptide-MPAM-15-Gi1/β1/γ2
30.00	Single	8ZWF	JR14a	8ZWF-C3a_B-JR14a
30.00	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
30.00	Single	9IK9	SST analogue	9IK9-SST1-SST analogue-Gi1/β1/γ2
30.00	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
30.00	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
29.63	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
29.63	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
29.63	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
29.63	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
29.41	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
29.41	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
29.41	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
29.41	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
29.41	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
29.41	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
29.41	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
29.41	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
29.41	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
29.41	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
29.41	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
29.41	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
29.41	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
29.41	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
29.41	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
29.41	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
29.41	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
29.41	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
29.41	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
29.41	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
29.41	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
29.41	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
29.41	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.41	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
29.41	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
29.41	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
29.41	Single	9K6L	SA0	9K6L-TAS2R16-SA0-Gi2/β1/γ2
29.41	Single	9KPE	SA0	9KPE-TAS2R16-SA0-Gi1/β1/γ2
29.41	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
29.41	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.41	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
29.41	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.41	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
29.17	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
29.17	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
29.17	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
29.17	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
29.17	Single	9IK8	SST analogue	9IK8-SST1-SST analogue-Gi1/β1/γ2
29.17	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
29.17	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
28.57	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
28.57	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
28.57	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
28.57	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
28.57	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
28.57	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
28.57	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
28.57	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
28.57	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
28.57	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
28.57	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
28.57	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
28.57	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
28.57	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
28.00	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
28.00	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
28.00	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
28.00	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
28.00	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
28.00	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
28.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
27.78	Single	3REY	XAC	3REY-A_2A-XAC
27.78	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
27.78	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
27.78	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
27.78	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
27.78	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
27.78	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
27.78	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
27.78	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
27.78	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
27.78	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
27.78	Single	6TPK	Retosiban	6TPK-OT-Retosiban
27.78	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
27.78	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
27.78	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
27.78	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
27.78	Single	7F61	PF-03654746	7F61-H₃-PF-03654746
27.78	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
27.78	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
27.78	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
27.78	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
27.78	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
27.78	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
27.78	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
27.78	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
27.78	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
27.78	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
27.78	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
27.78	Single	9JH3	CMF-019	9JH3-Apelin-CMF-019-Gi1/β1/γ2
27.78	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
27.78	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
27.78	Consensus	hca_on	Orthosteric Ligand	hca2_on
27.78	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
27.78	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
27.59	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
27.59	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
27.59	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
27.59	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
27.59	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
27.59	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
27.27	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
27.27	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
27.27	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
27.27	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
27.27	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
27.27	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
27.27	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
27.27	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
27.27	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
27.27	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
27.27	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
27.27	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
27.27	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
27.27	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
27.27	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
27.27	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
27.27	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
27.27	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
26.92	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
26.92	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
26.92	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
26.92	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
26.92	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
26.92	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
26.92	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
26.92	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
26.67	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
26.67	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
26.67	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
26.67	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
26.67	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
26.67	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
26.32	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
26.32	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
26.32	Single	5UEN	DU172	5UEN-A₁-DU172
26.32	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
26.32	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
26.32	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
26.32	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
26.32	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
26.32	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
26.32	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
26.32	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
26.32	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
26.32	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
26.32	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
26.32	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
26.32	Single	9JGK	Balovaptan	9JGK-5-HT_2B-Balovaptan
26.32	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
26.32	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
26.32	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
26.32	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
26.32	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
26.32	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
26.09	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
26.09	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
26.09	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
26.09	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
26.09	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
26.09	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
26.09	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
26.09	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
26.09	Single	9JF4	PD168368	9JF4-BB₁-PD168368
26.09	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
25.93	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
25.93	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
25.93	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
25.93	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
25.93	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
25.93	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
25.93	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
25.93	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
25.81	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
25.00	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
25.00	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
25.00	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
25.00	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
25.00	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
25.00	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
25.00	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
25.00	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
25.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
25.00	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
25.00	Single	7C4S	S1P	7C4S-S1P₃-S1P
25.00	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
25.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
25.00	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
25.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
25.00	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
25.00	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
25.00	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
25.00	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
25.00	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
25.00	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
25.00	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
25.00	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
25.00	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
25.00	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
25.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
25.00	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
25.00	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
25.00	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
25.00	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
25.00	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
25.00	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
25.00	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	9CIB	FCH-2296413	9CIB-HCA₂-FCH-2296413
25.00	Single	9GE2	ML184	9GE2-GPR55-ML184-chim(NtGi1-G13)/β1/γ2
25.00	Single	9HC0	4YI	9HC0-mGlu₅-4YI
25.00	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
25.00	Single	9KFK	Relaxin-3	9KFK-RXFP4-Relaxin-3-Gi2/β1/γ2
25.00	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
25.00	Consensus	blt_off	Orthosteric Ligand	blt1_off
25.00	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
25.00	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
25.00	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
25.00	Consensus	dp_off	Orthosteric Ligand	dp2_off
25.00	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
25.00	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
25.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
25.00	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
25.00	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
25.00	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
25.00	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
25.00	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
25.00	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
25.00	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
24.14	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
24.14	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
24.14	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
24.14	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
24.14	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
24.14	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
24.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
24.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
24.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
24.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
24.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
24.00	Single	9E82	SDF-1-beta	9E82-ACKR3-SDF-1-β-Arrestin2
24.00	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
24.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
23.81	Single	5XR8	AM841	5XR8-CB₁-AM841
23.81	Single	5XRA	AM11542	5XRA-CB₁-AM11542
23.81	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
23.81	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
23.81	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
23.81	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
23.81	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
23.81	Single	7P2L	4YI	7P2L-mGlu₅-4YI
23.81	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
23.81	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
23.81	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
23.81	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
23.81	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
23.81	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
23.81	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
23.81	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
23.81	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
23.81	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
23.81	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
23.53	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
23.53	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
23.53	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
23.53	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
23.53	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
23.53	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
23.53	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
23.53	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
23.53	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
23.53	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
23.33	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
23.33	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
23.33	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
23.33	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
23.33	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
23.33	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
23.08	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
23.08	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
23.08	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
23.08	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
23.08	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
22.73	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
22.73	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
22.73	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
22.73	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
22.73	Single	8XJN	Cloprosetnol	8XJN-TXA2-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	9DGI	Z8526711350	9DGI-CB₁-Z8526711350
22.73	Single	9GGG	I-BOP	9GGG-TXA2-I-BOP-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.73	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
22.73	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
22.73	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
22.73	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
22.73	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
22.73	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
22.73	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
22.73	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
22.58	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
22.58	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
22.58	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
22.58	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
22.58	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
22.58	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
22.22	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
22.22	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
22.22	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
22.22	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
22.22	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
22.22	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
22.22	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
22.22	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
22.22	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.22	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
22.22	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
22.22	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
22.22	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
22.22	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
22.22	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
22.22	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
22.22	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.22	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
22.22	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
22.22	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
22.22	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
22.22	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
21.88	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
21.88	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
21.74	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
21.74	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
21.74	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
21.74	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
21.74	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
21.74	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
21.74	Single	8XJO	U46619	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
21.74	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
21.74	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
21.74	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
21.74	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
21.74	Consensus	tp_on	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
21.43	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
21.43	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
21.43	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
21.43	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
21.43	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
21.43	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
21.43	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
21.43	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
21.43	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
21.43	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
21.43	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
21.43	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
21.43	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
21.21	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
21.21	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
21.05	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
21.05	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
21.05	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
21.05	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
21.05	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
21.05	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
21.05	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
21.05	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
21.05	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
21.05	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
21.05	Single	8K9L	Damgo	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
21.05	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
21.05	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Gi1/β1/γ2
21.05	Single	9KPD	SA0	9KPD-TAS2R16-SA0-chim(Gs-CtGt3)/β1/γ2
21.05	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
21.05	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
20.83	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
20.83	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
20.83	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
20.83	Single	9IZA	SCH900271	9IZA-HCA₂-SCH900271-Gi1/β1/γ2
20.83	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
20.83	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
20.83	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
20.83	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
20.69	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
20.69	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
20.69	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
20.69	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
20.69	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
20.69	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
20.69	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
20.59	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
20.59	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
20.00	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
20.00	Single	6D27	CAY10471	6D27-DP₂-CAY10471
20.00	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
20.00	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
20.00	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
20.00	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
20.00	Single	6GPS	MK0812	6GPS-CCR2-MK0812
20.00	Single	6IIV	Daltroban	6IIV-TXA2-Daltroban
20.00	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
20.00	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
20.00	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
20.00	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
20.00	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
20.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
20.00	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
20.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.00	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.00	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
20.00	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
20.00	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
20.00	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
20.00	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
20.00	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
20.00	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
20.00	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
20.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
20.00	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
20.00	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.00	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
20.00	Single	8WKY	PG-934	8WKY-MC₄-PG-934
20.00	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
20.00	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
20.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
20.00	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
20.00	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
20.00	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9HB3	Mambaquaretin-1	9HB3-V₂-Mambaquaretin-1
20.00	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9IZC	MK1903	9IZC-HCA₂-MK1903-Gi1/β1/γ2
20.00	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
20.00	Consensus	cck_off	Orthosteric Ligand	ccka_off
20.00	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
20.00	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
20.00	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
20.00	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.00	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
20.00	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
20.00	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
20.00	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
20.00	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
20.00	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
20.00	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
20.00	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
19.35	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
19.35	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
19.35	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
19.35	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
19.23	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
19.23	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
19.23	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
19.23	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
19.23	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
19.23	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
19.23	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
19.23	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
19.23	Single	9IQV	Muscarinic toxin 3	9IQV-Alpha1A-Muscarinic toxin 3
19.23	Single	9KFI	Relaxin-3	9KFI-RXFP3-Relaxin-3-Gi2/β1/γ2
19.23	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
19.23	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
19.23	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
19.23	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
19.23	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
19.05	Single	6GPX	MK0812	6GPX-CCR2-MK0812
19.05	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
19.05	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
19.05	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
19.05	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
19.05	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
19.05	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
19.05	Single	8WGB	VU0155041	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
19.05	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
19.05	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
19.05	Single	9KPF	SA0	9KPF-TAS2R16-SA0-Gi1/β1/γ2
19.05	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
19.05	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
19.05	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
19.05	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
19.05	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
19.05	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
18.92	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
18.75	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
18.75	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
18.75	Single	8Y02	Retinal	8Y02-OPN1SW-Retinal-Gi1/β1/γ2
18.75	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
18.75	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
18.75	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
18.52	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
18.52	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
18.52	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
18.52	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
18.52	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
18.52	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
18.52	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
18.52	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
18.52	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
18.52	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
18.52	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
18.18	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
18.18	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
18.18	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
18.18	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
18.18	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
18.18	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
18.18	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
18.18	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
18.18	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
18.18	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
18.18	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
18.18	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
18.18	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
18.18	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
18.18	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
18.18	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
18.18	Single	9EGO	YVF	9EGO-CB₁-YVF-Gi1/β1/γ2
18.18	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	9UY3	Anamorelin	9UY3-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
18.18	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
18.18	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
18.18	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
18.18	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
18.18	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
18.18	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
18.18	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
18.18	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
18.18	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
18.18	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
18.18	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
17.86	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
17.86	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
17.86	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
17.86	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
17.86	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
17.86	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
17.86	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
17.86	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
17.86	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
17.86	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
17.86	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
17.86	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
17.86	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
17.86	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
17.65	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
17.65	Single	9JHJ	C18:0 Ceramide	9JHJ-FPR2-ALX-C18:0 Ceramide-Gi1/β1/γ2
17.65	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
17.65	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
17.39	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
17.39	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
17.39	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
17.39	Single	6IIU	Ramatroban	6IIU-TXA2-Ramatroban
17.39	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
17.39	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
17.39	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
17.39	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
17.39	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
17.39	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
17.39	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
17.39	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
17.39	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
17.39	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
17.24	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
17.24	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
17.24	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
17.24	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
17.24	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
17.24	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
17.14	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
16.67	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
16.67	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
16.67	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
16.67	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
16.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
16.67	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
16.67	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
16.67	Single	7XP6	Strychnine	7XP6-TAS2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
16.67	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
16.67	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
16.67	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
16.67	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
16.67	Single	9B9Y	7DY	9B9Y-CB₁-7DY
16.67	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
16.67	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
16.67	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
16.67	Single	9GG5	U46619	9GG5-TXA2-U46619-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.67	Single	9IZD	CHBA	9IZD-HCA₁-CHBA-Gi1/β1/γ2
16.67	Single	9M1H	Prostaglandin E2	9M1H-EP₁-Prostaglandin E2-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
16.67	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
16.67	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
16.67	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
16.67	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
16.67	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
16.67	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
16.22	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
16.22	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
16.13	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
16.13	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
16.13	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
16.13	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
16.13	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
16.13	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
16.13	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
16.13	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
16.00	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
16.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
16.00	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
16.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
16.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
16.00	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
16.00	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
16.00	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
15.79	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
15.79	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
15.79	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
15.79	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
15.79	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
15.79	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
15.79	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
15.79	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
15.79	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
15.62	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
15.62	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
15.62	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
15.62	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
15.62	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
15.62	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
15.62	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
15.62	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
15.62	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
15.62	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
15.62	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
15.62	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
15.62	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
15.38	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
15.38	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
15.38	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
15.38	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
15.38	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
15.38	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
15.38	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
15.38	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
15.38	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
15.38	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
15.38	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
15.38	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
15.38	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
15.38	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
15.15	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
15.15	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
15.15	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
15.00	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
15.00	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
15.00	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
15.00	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
15.00	Single	8Y6Y	GLPG0974	8Y6Y-FFA2-GLPG0974
15.00	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070
15.00	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100
15.00	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
15.00	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
15.00	Single	9IXX	LTD4	9IXX-CysLT₂-LTD4-chim(NtGi1-Gs-CtGq)/β1/γ2
15.00	Single	9JMD	Azithromycin	9JMD-Motilin-Azithromycin-chim(Gs-CtGq)/β1/γ2
15.00	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
15.00	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
15.00	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
14.81	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
14.81	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
14.81	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
14.81	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
14.81	Single	9IQR	Muscarinic toxin 3	9IQR-α_2a-Muscarinic toxin 3
14.81	Single	9IQS	Muscarinic toxin 3	9IQS-M₄-Muscarinic toxin 3
14.81	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
14.81	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
14.71	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
14.71	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
14.71	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
14.71	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
14.29	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
14.29	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
14.29	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.29	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
14.29	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
14.29	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
14.29	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
14.29	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
14.29	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
14.29	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
14.29	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
14.29	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
14.29	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
14.29	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
14.29	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
14.29	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
14.29	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
14.29	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
14.29	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
14.29	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
14.29	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
14.29	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
14.29	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
14.29	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
13.95	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
13.89	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
13.89	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
13.89	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
13.89	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
13.79	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
13.79	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
13.79	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
13.79	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
13.79	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
13.79	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
13.79	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
13.79	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
13.79	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
13.79	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
13.79	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
13.79	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
13.64	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
13.64	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
13.64	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
13.64	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
13.64	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
13.64	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.64	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
13.64	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
13.64	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
13.64	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
13.64	Consensus	ep_off	Orthosteric Ligand	ep4_off
13.64	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
13.51	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
13.51	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
13.51	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
13.33	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
13.33	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
13.33	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
13.33	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
13.33	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
13.33	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
13.33	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
13.33	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
13.33	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
13.33	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
13.33	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
13.33	Consensus	pac_on	Orthosteric Ligand	pac1_on
13.33	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
13.16	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
13.04	Single	5TZR	MK8666	5TZR-FFA1-MK8666
13.04	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
13.04	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
13.04	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
13.04	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
13.04	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
13.04	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
13.04	Single	9CLW	TUG-1375	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.04	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
13.04	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
13.04	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.04	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.90	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
12.90	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
12.90	Single	6FJ3	PTH	6FJ3-PTH1-PTH
12.90	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.90	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
12.90	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
12.90	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
12.90	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
12.90	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
12.90	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
12.90	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
12.90	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
12.90	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
12.90	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
12.90	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
12.90	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
12.50	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
12.50	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
12.50	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
12.50	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
12.50	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
12.50	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
12.50	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
12.50	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
12.50	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
12.50	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
12.50	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.50	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
12.50	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
12.50	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
12.50	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
12.50	Single	8Y6W	TUG-1375	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
12.50	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
12.50	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
12.50	Single	9CM3	TUG-1375	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.50	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
12.50	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.50	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
12.50	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
12.50	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
12.12	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.12	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
12.12	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
12.12	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
12.12	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
12.12	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
12.12	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
12.12	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
12.00	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
12.00	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
12.00	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
12.00	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
12.00	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
12.00	Single	9JH5	C16:0 Ceramide	9JH5-CysLT₂-C16:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
11.76	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
11.76	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
11.54	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
11.54	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
11.54	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
11.54	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
11.54	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
11.54	Single	9CM7	TUG-1375	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
11.54	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	9NS9	TUG-1375	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
11.54	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
11.54	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
11.43	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
11.11	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
11.11	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
11.11	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
11.11	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
11.11	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
11.11	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
11.11	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
11.11	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
11.11	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
11.11	Single	9J0I	UDP-Glucuronic acid	9J0I-P2Y₁₄-UDP-Glucuronic acid-Gi1/β1/γ2
11.11	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
10.81	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
10.81	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
10.71	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
10.71	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
10.71	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
10.71	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
10.71	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
10.71	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
10.71	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
10.71	Single	9J0F	NADH	9J0F-P2Y₁₄-NADH-Gi1/β1/γ2
10.71	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
10.71	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
10.53	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
10.53	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
10.53	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
10.53	Single	8YKD	Dehydroepiandrosterone	8YKD-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
10.53	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
10.34	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.34	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.34	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.34	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
10.34	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.34	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.00	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
10.00	Single	5U09	Taranabant	5U09-CB₁-Taranabant
10.00	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
10.00	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
10.00	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
10.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
10.00	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
10.00	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
10.00	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
10.00	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
10.00	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
10.00	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
10.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
9.68	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
9.68	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
9.68	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
9.68	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
9.68	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
9.68	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
9.52	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
9.52	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
9.52	Single	8IYX	YL-365	8IYX-GPR34-YL-365
9.52	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
9.52	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
9.52	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
9.52	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
9.52	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
9.52	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
9.38	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
9.38	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
9.38	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
9.38	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.09	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
9.09	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
9.09	Single	8ZYY	Neurotensin peptide 8-13	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
8.82	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
8.82	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
8.82	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
8.70	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.70	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
8.70	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
8.70	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
8.70	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
8.70	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
8.70	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
8.57	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
8.33	Single	5V56	TC114	5V56-SMO-TC114
8.33	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
8.33	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
8.33	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
8.33	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
8.33	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
8.33	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
8.33	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
8.00	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
8.00	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
8.00	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
8.00	Single	6OS2	TRV026	6OS2-AT₁-TRV026
8.00	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
8.00	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.00	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
8.00	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
7.89	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
7.89	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
7.69	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
7.69	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
7.69	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
7.69	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
7.69	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
7.41	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
7.41	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
7.41	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.41	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
7.41	Single	8XQJ	JN241	8XQJ-Apelin-JN241
7.41	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
7.14	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
7.14	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
7.14	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
7.14	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
7.14	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
7.14	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
7.14	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
6.90	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
6.90	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
6.90	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
6.67	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
6.67	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
6.67	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
6.45	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
6.25	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/β1/γ2
6.06	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
5.88	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
5.88	Single	7V68	LY2119620	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
5.88	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
5.88	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
5.88	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
5.88	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
5.56	Single	7VDM	Substance-P	7VDM-MRGPRX2-Substance-P-Gi1/β1/γ2
5.56	Single	7Y14	Beta-Alanine	7Y14-MRGPRD-β-Alanine
5.26	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
5.26	Single	7Y12	Beta-Alanine	7Y12-MRGPRD-β-Alanine-Gi1/β1/γ2
5.26	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
5.00	Single	6LI0	C17	6LI0-GPR52-C17
5.00	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
5.00	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
5.00	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
5.00	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
5.00	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
5.00	Single	9LMP	NE52-QQ57	9LMP-GPR4-NE52-QQ57
5.00	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg4_on
5.00	Consensus	adgrg_on_gp	Orthosteric Ligand	adgrg2_on_gp adgrg4_on_gp
5.00	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
5.00	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
4.76	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
4.76	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
4.76	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
4.76	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
4.76	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
4.76	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
4.76	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.76	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
4.76	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.76	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
4.55	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
4.55	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
4.55	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
4.55	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
4.55	Single	7T94	LY2119620	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
4.55	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
4.55	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	8JD6	VU0364770	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
4.55	Single	9JFU	NE52-QQ57	9JFU-GPR4-NE52-QQ57
4.55	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.35	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
4.35	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
4.35	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
4.35	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
4.35	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
4.35	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
4.35	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
4.35	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.35	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.17	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
4.17	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.17	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.17	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
4.17	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
4.17	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.17	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
4.17	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
4.17	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
4.00	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
4.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
4.00	Single	5V57	TC114	5V57-SMO-TC114
4.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
4.00	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
4.00	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
4.00	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
4.00	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.00	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
4.00	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
4.00	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
4.00	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
4.00	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.85	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
3.85	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
3.85	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
3.85	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
3.85	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
3.85	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
3.85	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
3.85	Single	8XQJ	JN241	8XQJ-Apelin-JN241
3.85	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
3.85	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
3.85	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
3.85	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.85	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
3.85	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.70	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
3.70	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.70	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
3.70	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
3.70	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
3.70	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
3.70	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116
3.70	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.70	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.57	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
3.57	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
3.57	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
3.57	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
3.57	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
3.57	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
3.45	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
3.45	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.45	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8

Consensus Members
	Id	Members
	5ht_on_gp	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
	adrenergic_on_gp	alpha_on_gp beta_on_gp
	dopamine_on_gp	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
	histamine_on_gp	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
	muscarinic_on_gp	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
	trace-amine_on_gp	ta1_on_gp

Net Summary
I_min	2.77146
Number of Linked Nodes	980
Number of Links	1171
Number of Hubs	182
Number of Links mediated by Hubs	699
Number of Communities	25
Number of Nodes involved in Communities	242
Number of Links involved in Communities	349

Path Summary
Number Of Nodes in MetaPath	109
Number Of Links MetaPath	108
Number of Shortest Paths	13782459
Length Of Smallest Path	3
Average Path Length	53.0042
Length of Longest Path	79
Minimum Path Strength	0.195727
Average Path Strength	4.67344
Maximum Path Strength	21.2858
Minimum Path Correlation	0.700532
Average Path Correlation	0.994974
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.35135
Average % Of Corr. Nodes	21.7034
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	57.3232
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following differences:
	Id	1^st Network	2^nd Network
	amine_off_on_gp	amine_on_gp	amine_off

This network is also present in following consensuses:
	Id	Components
	amine_offon_gp	amine_on_gp amine_off
	class-a_on_gp	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download amine_on_gp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.