psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.30	G.HN.33	3.58736	Yes	No	0	8	4
2	G.HN.40	b.b5x2	8.13958	No	Yes	0	7	7
3	G.HN.43	b.b5x3	4.68458	No	Yes	0	8	9
4	G.HN.44	b.b5x3	9.03292	No	Yes	0	6	9
5	G.HN.47	b.b4x2	2.7025	No	No	0	6	8
6	G.HN.50	b.b4x2	7.64431	No	No	0	5	8
7	G.HN.51	b.l1x4	4.24833	No	No	0	4	6
8	G.S1.01	G.S3.02	5.0525	No	Yes	0	6	3
9	G.S1.02	G.S3.03	5.54847	No	Yes	0	4	7
10	G.S1.02	G.h2s4.05	4.39278	No	No	0	4	7
11	G.S1.03	G.S3.04	2.87833	No	Yes	2	9	6
12	G.S1.03	G.S3.06	4.37472	No	Yes	2	9	6
13	G.S1.04	G.S4.03	2.795	No	No	0	7	7
14	G.S1.05	G.h2s4.01	11.0612	No	Yes	0	9	9
15	G.S1.05	G.h2s4.04	3.51806	No	No	0	9	9
16	G.S1.05	G.S4.02	6.08528	No	Yes	0	9	7
17	G.H1.01	G.S1.06	3.19208	No	Yes	17	9	8
18	G.S1.06	G.S3.05	5.83333	Yes	Yes	0	8	6
19	G.S1.06	G.S3.07	3.67528	Yes	No	17	8	9
20	G.S1.06	G.S4.03	3.48597	Yes	No	0	8	7
21	G.H3.12	G.S1.07	3.13181	No	No	0	8	9
22	G.H1.01	G.s1h1.01	2.71319	No	No	0	9	9
23	G.H3.01	G.s1h1.04	2.92069	Yes	No	0	9	8
24	G.H1.04	G.S4.05	2.72861	No	No	0	7	7
25	G.H1.04	G.S5.05	4.13528	No	Yes	0	7	9
26	G.H1.08	G.S2.06	5.5975	No	Yes	0	8	8
27	G.hfs2.07	b.l7x4	3.06403	No	No	0	8	9
28	G.S2.01	b.l5x5	3.55569	No	Yes	0	9	9
29	G.S2.02	G.S3.07	3.46778	No	No	0	5	9
30	G.S2.03	G.S3.04	7.79917	No	Yes	2	8	6
31	G.S2.03	G.S3.06	9.2475	No	Yes	2	8	6
32	G.S2.04	G.S3.05	3.56014	No	Yes	0	7	6
33	G.S2.05	G.S3.02	6.37042	No	Yes	2	3	3
34	G.S2.05	G.S3.04	7.19931	No	Yes	2	3	6
35	G.S2.06	G.S3.03	12.2664	Yes	Yes	0	8	7
36	G.H5.04	G.S2.06	3.39986	No	Yes	0	7	8
37	G.S2.07	G.S3.02	9.32208	No	Yes	0	3	3
38	G.S2.08	G.s2s3.01	4.93444	Yes	No	12	5	4
39	G.H5.04	G.S2.08	3.68417	No	Yes	0	7	5
40	G.H5.05	G.S2.08	3.78167	Yes	Yes	12	5	5
41	G.H5.08	G.S2.08	6.70958	Yes	Yes	12	8	5
42	G.H5.08	G.s2s3.01	6.79806	Yes	No	12	8	4
43	G.S3.01	G.S3.03	5.44333	No	Yes	0	4	7
44	G.S3.01	I2x51	6.49056	No	Yes	0	4	7
45	G.S3.04	G.S3.06	6.02569	Yes	Yes	2	6	6
46	G.S3.06	G.h2s4.01	2.91792	Yes	Yes	2	6	9
47	G.S3.06	b.l5x5	13.5029	Yes	Yes	2	6	9
48	G.H2.07	G.S3.08	8.00375	Yes	No	0	9	9
49	G.H2.07	G.s3h2.03	6.71056	Yes	No	2	9	9
50	G.s3h2.03	b.l7x4	2.97	No	No	0	9	9
51	G.s3h2.03	b.l9x6	6.02722	No	Yes	2	9	8
52	G.H2.02	b.l9x6	3.07417	No	Yes	0	8	8
53	G.H2.03	G.H2.05	4.73583	No	No	0	9	7
54	G.H2.04	G.H2.07	5.40236	No	Yes	0	9	9
55	G.H2.04	G.H3.08	4.92556	No	No	0	9	9
56	G.H2.06	b.l9x6	2.86889	Yes	Yes	2	9	8
57	G.H2.06	b.b14x1	8.44	Yes	No	2	9	8
58	G.H2.06	b.l17x6	7.52861	Yes	Yes	2	9	9
59	G.H2.07	G.h2s4.01	3.11639	Yes	Yes	2	9	9
60	G.H2.07	b.l9x6	4.20708	Yes	Yes	2	9	8
61	G.H2.09	G.H3.17	6.06597	No	Yes	2	8	4
62	G.H2.09	b.l27x1	3.63167	No	Yes	2	8	9
63	G.H2.10	b.b2x1	3.82611	No	Yes	2	6	8
64	G.H2.10	b.l3x1	4.59889	No	Yes	2	6	9
65	G.h2s4.01	b.l5x5	11.2474	Yes	Yes	2	9	9
66	G.h2s4.01	b.l7x2	2.8425	Yes	No	2	9	9
67	G.h2s4.02	G.h2s4.03	4.01778	Yes	No	2	7	5
68	G.h2s4.02	b.l1x6	7.88	Yes	Yes	2	7	9
69	G.h2s4.03	b.l1x6	4.22417	No	Yes	2	5	9
70	G.H3.18	G.S4.02	4.245	Yes	Yes	4	9	7
71	G.S4.02	G.S5.02	4.09847	Yes	No	4	7	6
72	G.S4.03	G.S5.05	2.73847	No	Yes	0	7	9
73	G.S4.04	G.S4.06	2.74736	No	No	0	9	7
74	G.H3.08	G.S4.04	5.29611	No	No	0	9	9
75	G.H3.09	G.S4.04	8.11417	Yes	No	0	9	9
76	G.H3.05	G.S4.06	3.19653	No	No	0	9	7
77	G.H4.15	G.S4.06	4.62306	Yes	No	0	8	7
78	G.S5.06	G.s4h3.01	3.71417	No	No	0	8	7
79	G.HG.04	G.s4h3.01	8.37347	Yes	No	0	8	7
80	G.HG.03	G.s4h3.02	3.37819	Yes	No	18	6	9
81	G.H3.01	G.s4h3.03	6.66819	Yes	No	0	9	8
82	G.s4h3.04	G.s4h3.05	4.21708	Yes	No	0	8	9
83	G.HG.07	G.s4h3.04	5.40681	No	Yes	0	9	8
84	G.H3.01	G.s4h3.06	3.22458	Yes	No	0	9	8
85	G.H3.03	G.s4h3.15	5.73958	No	No	0	4	9
86	G.hgh4.01	G.s4h3.15	6.38542	No	No	0	4	9
87	G.H3.03	G.hgh4.02	4.25875	No	Yes	0	4	8
88	G.H3.06	G.H4.14	3.77944	No	Yes	0	7	6
89	G.H3.06	G.H4.15	6.18722	No	Yes	0	7	8
90	G.H3.06	G.h4s6.01	3.33917	No	No	0	7	4
91	G.H3.09	G.S5.02	4.58542	Yes	No	4	9	6
92	G.H3.09	G.S5.04	2.85944	Yes	Yes	4	9	9
93	G.H3.09	G.H4.15	5.13625	Yes	Yes	4	9	8
94	G.H3.10	G.H3.14	2.89292	No	No	0	4	8
95	G.H3.10	G.h4s6.01	5.97139	No	No	0	4	4
96	G.H3.13	G.S5.02	2.96472	Yes	No	4	5	6
97	G.H3.14	G.h4s6.03	4.16917	No	No	0	8	4
98	G.H3.15	G.H3.18	6.36792	No	Yes	0	8	9
99	G.H3.16	G.H3.17	11.6935	No	Yes	0	4	4
100	G.H3.18	G.h3s5.03	3.38625	Yes	No	4	9	8
101	G.H5.14	G.S5.01	7.72389	No	No	0	6	7
102	G.H5.10	G.S5.03	3.96694	No	No	0	7	8
103	G.S5.04	G.S5.06	3.63306	Yes	No	0	9	8
104	G.H4.15	G.S5.04	5.75111	Yes	Yes	4	8	9
105	G.S5.04	G.S6.03	4.67167	Yes	No	4	9	4
106	G.S5.05	G.S6.04	2.70222	Yes	No	0	9	8
107	G.H5.03	G.S5.05	4.54792	Yes	Yes	11	8	9
108	G.H5.07	G.S5.05	2.81111	No	Yes	0	8	9
109	G.S5.06	G.S6.05	5.08764	No	Yes	0	8	5
110	G.S5.07	G.s6h5.01	4.79139	No	Yes	0	9	9
111	G.HG.03	G.s5hg.01	5.07208	Yes	No	18	6	9
112	G.HG.01	G.S6.05	5.96917	No	Yes	4	5	5
113	G.HG.15	G.hgh4.05	2.82625	No	Yes	0	7	6
114	G.hgh4.02	G.hgh4.04	3.21597	Yes	No	0	8	5
115	G.H4.10	G.hgh4.02	3.44056	Yes	Yes	19	6	8
116	G.H4.14	G.hgh4.02	4.29097	Yes	Yes	19	6	8
117	G.H4.05	G.hgh4.05	6.93486	No	Yes	0	4	6
118	G.H4.10	G.hgh4.05	18.3363	Yes	Yes	0	6	6
119	G.H4.05	G.hgh4.08	5.43736	No	Yes	0	4	1
120	G.H4.10	G.H4.14	8.17639	Yes	Yes	19	6	6
121	G.H4.12	G.H4.16	4.48417	Yes	No	4	5	3
122	G.H4.12	G.S6.03	7.50875	Yes	No	4	5	4
123	G.H4.16	G.S6.03	3.49972	No	No	4	3	4
124	G.h4s6.02	G.h4s6.08	2.98292	Yes	No	0	7	5
125	G.S6.01	G.h4s6.02	5.23375	No	Yes	0	5	7
126	G.S6.02	G.h4s6.12	4.35042	Yes	No	0	8	4
127	G.H5.10	G.S6.02	6.75097	No	Yes	0	7	8
128	G.H5.13	G.S6.02	6.57792	No	Yes	0	7	8
129	G.H5.06	G.S6.04	11.9082	No	No	0	3	8
130	G.H5.05	G.H5.09	2.75833	Yes	No	0	5	4
131	G.H5.08	I2x51	4.99222	Yes	Yes	0	8	7
132	G.H5.12	I2x51	4.22222	No	Yes	0	7	7
133	G.H5.15	I2x50	2.87333	No	No	0	8	9
134	G.H5.16	I2x50	3.23569	No	No	0	7	9
135	3x53	G.H5.19	5.75528	No	No	0	9	8
136	G.H5.20	G.H5.25	2.92028	No	Yes	0	8	6
137	3x54	G.H5.20	4.81542	No	No	0	8	8
138	G.H5.21	G.H5.26	3.10222	No	No	0	4	5
139	G.H5.23	G.H5.25	2.79417	No	Yes	0	4	6
140	3x50	G.H5.23	11.9911	Yes	No	0	9	4
141	6x29	G.H5.26	9.69083	No	No	0	8	5
142	b.1x4	b.1x7	2.78361	No	No	0	8	8
143	b.1x13	b.1x16	3.66653	No	No	0	1	4
144	b.1x15	b.1x19	3.11431	No	No	0	7	6
145	b.h2x2	b.lh12x4	3.6	No	No	0	1	3
146	b.h2x3	b.lh12x4	4.52681	No	No	0	1	3
147	b.b21x5	b.h2x1	5.53444	Yes	No	0	4	5
148	b.h2x5	b.l24x2	3.82917	No	No	0	5	6
149	b.lhb1x1	b.lhb1x2	3.46181	No	No	0	1	1
150	b.lhb1x4	b.lhb1x5	2.90694	No	No	0	1	1
151	b.lhb1x6	b.lhb1x9	2.88111	Yes	No	0	3	3
152	b.l22x5	b.lhb1x6	3.21542	Yes	Yes	13	9	3
153	b.b24x7	b.lhb1x6	4.23806	No	Yes	13	9	3
154	b.lhb1x6	g.ctx6	2.93861	Yes	Yes	13	3	6
155	b.lhb1x10	b.lhb1x8	7.88472	No	No	0	4	2
156	b.lhb1x11	b.lhb1x9	3.05847	No	No	0	4	3
157	b.b25x7	b.lhb1x11	5.79194	No	No	0	7	4
158	b.lhb1x11	g.ctx5	3.02361	No	No	0	4	9
159	b.b1x1	b.b1x3	3.79139	No	No	0	5	7
160	b.b1x2	b.b28x4	7.00708	No	Yes	7	3	6
161	b.b1x2	b.b28x6	9.53333	No	Yes	7	3	9
162	b.b1x3	b.b28x7	9.94403	No	No	0	7	9
163	b.b1x4	b.b5x1	2.945	No	No	0	7	5
164	b.b1x4	b.b28x5	4.29792	No	No	6	7	5
165	b.b1x4	g.ctx16	7.68944	No	Yes	6	7	8
166	b.b1x5	b.l1x1	6.64875	No	No	0	3	7
167	b.b1x5	b.b28x4	6.86167	No	Yes	0	3	6
168	b.b1x6	b.b4x6	19.0288	No	Yes	0	9	9
169	b.b1x6	b.b5x1	2.78542	No	No	0	9	5
170	b.b1x6	b.b28x3	5.40125	No	Yes	0	9	7
171	b.b28x2	b.l1x1	6.20514	No	No	0	4	7
172	b.b5x3	b.l1x2	2.90667	Yes	No	0	9	9
173	b.l1x3	b.l1x7	8.32278	Yes	No	0	9	9
174	b.b3x4	b.l1x3	7.5725	No	Yes	10	9	9
175	b.b3x6	b.l1x3	11.2164	No	Yes	0	9	9
176	b.b4x4	b.l1x3	9.42889	No	Yes	10	8	9
177	b.b4x6	b.l1x3	4.085	Yes	Yes	10	9	9
178	b.l1x4	b.l3x2	4.20542	No	Yes	0	6	9
179	b.l1x5	b.l3x2	2.89403	No	Yes	0	7	9
180	b.b2x1	b.l1x6	3.78208	Yes	Yes	2	8	9
181	b.l1x6	b.l3x1	4.97319	Yes	Yes	2	9	9
182	b.l1x6	b.l27x1	19.8883	Yes	Yes	2	9	9
183	b.b28x3	b.l1x7	2.97222	Yes	No	0	7	9
184	b.b2x1	b.l3x1	12.2447	Yes	Yes	2	8	9
185	b.b2x3	b.b2x5	3.45625	No	Yes	0	6	7
186	b.b26x2	b.b2x3	4.95	No	No	0	7	6
187	b.b2x4	b.b6x5	3.11861	No	Yes	0	6	6
188	b.b10x4	b.b2x4	11.4564	No	No	0	6	6
189	b.b2x5	b.b3x2	9.85458	Yes	No	0	7	5
190	b.b2x5	b.l4x1	3.60292	Yes	No	0	7	5
191	b.b2x5	b.l26x1	11.4544	Yes	No	0	7	7
192	b.b27x2	b.b2x5	4.26917	No	Yes	0	5	7
193	b.b6x5	b.l2x1	4.85	Yes	No	0	6	5
194	b.l2x3	b.l2x5	4.03403	No	No	0	8	5
195	b.l26x1	b.l2x4	7.5275	No	No	20	7	5
196	b.l26x3	b.l2x4	9.9375	No	No	20	7	5
197	b.b4x7	b.l2x5	15.285	No	No	0	8	5
198	b.l2x5	b.l4x2	21.8074	No	Yes	0	5	4
199	b.b3x1	b.b6x5	3.19028	No	Yes	0	5	6
200	b.b3x2	b.b4x6	4.71542	No	Yes	0	5	9
201	b.b3x3	b.b4x3	2.85583	Yes	Yes	0	8	7
202	b.b3x3	b.b4x5	4.03083	Yes	No	0	8	7
203	b.b3x3	b.b6x5	5.3825	Yes	Yes	0	8	6
204	b.b3x3	b.b7x2	3.18333	Yes	No	0	8	8
205	b.b3x4	b.b4x6	5.81708	No	Yes	10	9	9
206	b.b28x3	b.b3x4	3.16792	Yes	No	0	7	9
207	b.b3x5	b.l5x6	3.48569	No	No	0	9	9
208	b.b3x6	b.l3x2	6.03208	No	Yes	0	9	9
209	b.l3x1	b.l5x5	6.31444	Yes	Yes	2	9	9
210	b.b4x2	b.l3x2	5.39778	No	Yes	0	8	9
211	b.b4x1	b.l5x1	3.42	No	Yes	0	8	8
212	b.b4x3	b.b5x7	6.14444	Yes	Yes	0	7	7
213	b.b4x3	b.l5x1	4.69181	Yes	Yes	14	7	8
214	b.b4x3	b.b7x4	5.04875	Yes	Yes	14	7	8
215	b.b4x4	b.b4x6	12.9844	No	Yes	10	8	9
216	b.b4x4	b.b5x3	3.87569	No	Yes	10	8	9
217	b.b4x5	b.b5x5	5.8375	No	Yes	0	7	5
218	b.b4x5	b.l8x1	3.09125	No	No	0	7	5
219	b.b4x6	b.b5x3	9.48944	Yes	Yes	10	9	9
220	b.b4x7	b.l4x3	6.62597	No	No	0	8	6
221	b.l4x1	b.l4x2	3.24903	No	Yes	6	5	4
222	b.l4x1	g.ctx16	4.20014	No	Yes	6	5	8
223	b.l4x2	g.ctx15	10.7229	Yes	No	0	4	9
224	b.l4x2	g.ctx16	5.87528	Yes	Yes	6	4	8
225	b.b5x2	b.l4x3	8.10611	Yes	No	0	7	6
226	b.b5x4	b.b5x5	6.555	No	Yes	0	5	5
227	b.b5x5	b.l8x8	2.92014	Yes	No	0	5	4
228	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
229	b.b5x7	b.b8x4	5.03639	Yes	Yes	0	7	6
230	b.b5x7	b.l8x8	8.08583	Yes	No	0	7	4
231	b.l5x1	b.l5x6	3.29042	Yes	No	0	8	9
232	b.b7x4	b.l5x1	4.31917	Yes	Yes	14	8	8
233	b.b8x4	b.l5x1	4.70625	Yes	Yes	14	6	8
234	b.b9x3	b.l5x2	5.68681	No	No	0	6	6
235	b.l5x3	b.l7x3	9.24264	No	No	0	8	9
236	b.l5x5	b.l7x2	3.64125	Yes	No	2	9	9
237	b.b6x1	b.l7x1	3.20167	No	No	0	9	9
238	b.b6x1	b.l9x6	4.48861	No	Yes	0	9	8
239	b.b10x2	b.b6x2	2.81667	No	No	0	6	8
240	b.b6x5	b.l6x4	4.06569	Yes	No	0	6	5
241	b.b10x5	b.l6x1	4.17972	Yes	No	0	9	6
242	b.b10x5	b.l6x2	2.8275	Yes	No	0	9	6
243	b.l6x3	b.l6x5	6.93264	No	Yes	15	6	4
244	b.l10x3	b.l6x3	8.1975	No	No	15	6	6
245	b.b7x1	b.l6x5	3.71583	Yes	Yes	15	4	4
246	b.l6x5	b.l8x2	7.79028	Yes	No	0	4	4
247	b.l10x3	b.l6x5	3.90764	No	Yes	15	6	4
248	b.b7x1	b.b8x3	3.14264	Yes	No	0	4	6
249	b.b7x1	b.b8x5	9.77208	Yes	No	0	4	4
250	b.b7x1	b.l10x3	5.07861	Yes	No	15	4	6
251	b.b7x2	b.l8x1	3.00069	No	No	0	8	5
252	b.b10x5	b.b7x3	3.09819	Yes	No	0	9	9
253	b.b7x4	b.b8x4	3.30472	Yes	Yes	14	8	6
254	b.l7x2	b.l9x6	2.79792	No	Yes	2	9	8
255	b.l7x3	b.l7x5	6.33889	No	No	0	9	6
256	b.l7x4	b.l9x5	4.12319	No	No	0	9	8
257	b.b9x3	b.l7x5	3.70083	No	No	0	6	6
258	b.b8x2	b.b9x3	4.45264	No	No	0	8	6
259	b.b8x3	b.l12x1	3.26958	No	No	0	6	6
260	b.b8x4	b.l8x10	6.01194	Yes	No	0	6	4
261	b.l8x3	b.l8x9	3.34222	No	No	0	3	3
262	b.l8x5	b.l8x9	3.13431	No	No	0	3	3
263	b.b12x6	b.b9x4	14.9163	Yes	No	0	8	9
264	b.b12x6	b.l9x2	2.90917	Yes	No	0	8	5
265	b.b11x4	b.l9x3	5.32778	Yes	Yes	2	9	9
266	b.b11x6	b.l9x3	15.6346	No	Yes	2	9	9
267	b.l11x2	b.l9x3	7.68472	Yes	Yes	2	9	9
268	b.b12x2	b.l9x3	3.19625	No	Yes	2	7	9
269	b.b12x4	b.l9x3	2.86875	No	Yes	2	4	9
270	b.b12x6	b.l9x3	3.20403	Yes	Yes	2	8	9
271	b.l11x2	b.l9x4	8.09167	Yes	No	0	9	5
272	b.l11x2	b.l9x5	2.91111	Yes	No	0	9	8
273	b.l11x1	b.l9x6	5.2325	No	Yes	2	9	8
274	b.l13x6	b.l9x6	7.45444	Yes	Yes	2	9	8
275	b.b14x1	b.l9x6	3.24208	No	Yes	2	8	8
276	b.b11x4	b.l9x7	4.36	Yes	No	0	9	7
277	b.b10x1	b.b11x5	2.92042	No	No	0	9	6
278	b.b10x2	b.b14x3	2.90958	No	No	0	6	5
279	b.b10x3	b.b11x4	3.35653	No	Yes	0	8	9
280	b.b10x4	b.b14x5	2.84889	No	No	0	6	5
281	b.b10x5	b.b11x2	8.61722	Yes	No	0	9	7
282	b.b11x1	b.l10x1	3.91694	No	No	0	5	3
283	b.b14x5	b.l10x1	3.01694	No	No	0	5	3
284	b.l10x1	b.l14x4	4.19625	No	No	0	3	1
285	b.l10x2	b.l10x4	2.91833	No	No	0	5	3
286	b.b11x1	b.l10x2	6.40097	No	No	0	5	5
287	b.l10x4	b.l12x2	5.84111	No	No	21	3	6
288	b.b11x1	b.b12x5	5.73028	No	Yes	0	5	6
289	b.b11x2	b.b12x6	3.14528	No	Yes	0	7	8
290	b.b11x2	b.l12x1	3.23042	No	No	0	7	6
291	b.b11x3	b.b12x5	2.75236	No	Yes	0	5	6
292	b.b11x3	b.b15x1	2.9475	No	Yes	0	5	9
293	b.b11x4	b.b12x6	8.72472	Yes	Yes	2	9	8
294	b.b11x5	b.l13x7	4.44264	No	No	0	6	9
295	b.b11x5	b.b14x3	4.71139	No	No	0	6	5
296	b.b11x6	b.l11x1	3.42681	No	No	2	9	9
297	b.b11x6	b.l11x2	7.81236	No	Yes	2	9	9
298	b.l11x1	b.l13x6	3.58708	No	Yes	2	9	9
299	b.b12x2	b.l11x2	6.26444	No	Yes	2	7	9
300	b.b12x2	b.l13x1	2.87833	No	No	0	7	2
301	b.b12x3	b.b13x7	4.24875	No	Yes	0	8	7
302	b.b12x4	b.b12x6	3.92778	No	Yes	2	4	8
303	b.b12x4	b.b13x3	3.55847	No	No	2	4	4
304	b.b12x6	b.b13x3	12.3054	Yes	No	2	8	4
305	b.b12x7	b.l12x2	4.54833	No	No	21	9	6
306	b.b12x7	b.l12x3	8.39097	No	No	0	9	5
307	b.b13x2	b.l12x3	4.96028	No	No	0	4	5
308	b.b13x5	b.b13x7	5.72958	No	Yes	0	4	7
309	b.b13x7	b.b15x1	8.06736	Yes	Yes	5	7	9
310	b.b13x7	b.b16x6	13.8237	Yes	Yes	5	7	8
311	b.b13x7	b.b17x1	3.72306	Yes	No	0	7	4
312	b.l13x3	b.l13x7	5.90222	Yes	No	5	9	9
313	b.b15x3	b.l13x3	4.28014	No	Yes	5	9	9
314	b.b15x5	b.l13x3	5.97542	No	Yes	0	8	9
315	b.b16x4	b.l13x3	13.9551	Yes	Yes	5	6	9
316	b.b16x6	b.l13x3	3.65833	Yes	Yes	5	8	9
317	b.l13x4	b.l15x2	6.82583	No	No	0	3	9
318	b.l13x6	b.l15x1	3.21972	Yes	No	2	9	7
319	b.b14x2	b.b18x3	3.505	No	Yes	0	7	8
320	b.b14x3	b.b15x1	3.21528	No	Yes	0	5	9
321	b.b14x4	b.b18x5	4.65944	No	Yes	0	8	5
322	b.b18x5	b.l14x1	5.06528	Yes	No	0	5	4
323	b.l14x2	b.l18x4	2.70667	No	No	0	4	7
324	b.l14x3	b.l14x5	8.89944	No	No	0	5	5
325	b.l14x5	b.l16x2	5.90833	No	No	0	5	9
326	b.b16x5	b.l14x6	3.94125	Yes	No	0	5	3
327	b.b15x1	b.b16x6	10.6615	Yes	Yes	5	9	8
328	b.b15x2	b.b16x5	3.02139	Yes	Yes	0	6	5
329	b.b15x2	b.b18x3	4.96917	Yes	Yes	3	6	8
330	b.b15x2	b.b18x5	7.02806	Yes	Yes	0	6	5
331	b.b15x2	b.b19x2	6.84667	Yes	Yes	3	6	6
332	b.b15x3	b.b16x6	5.32069	No	Yes	5	9	8
333	b.l15x1	b.l17x6	9.68208	No	Yes	2	7	9
334	b.b16x2	b.l15x2	6.97361	No	No	0	5	9
335	b.b16x4	b.b16x6	7.57222	Yes	Yes	5	6	8
336	b.b16x4	b.b17x3	6.2425	Yes	No	5	6	5
337	b.b16x4	b.b17x6	12.4517	Yes	No	0	6	7
338	b.b16x5	b.b17x5	3.27097	Yes	Yes	0	5	7
339	b.b16x5	b.l20x1	5.19111	Yes	No	0	5	6
340	b.b16x6	b.b17x3	6.04125	Yes	No	5	8	5
341	b.b16x7	b.l16x3	7.81347	No	No	0	9	3
342	b.b16x7	b.b17x4	10.7022	No	No	0	9	5
343	b.b17x3	g.h1x10	3.94069	No	No	0	5	9
344	b.b17x5	b.b17x7	8.06958	Yes	Yes	3	7	8
345	b.b17x5	b.b21x1	8.06667	Yes	Yes	3	7	7
346	b.b17x6	g.h1x14	4.56708	No	No	0	7	9
347	b.b17x7	b.b19x2	8.09847	Yes	Yes	3	8	6
348	b.b17x7	b.b20x6	8.15903	Yes	Yes	3	8	6
349	b.b17x7	b.b21x1	4.61208	Yes	Yes	3	8	7
350	b.l17x3	b.l17x7	6.13139	Yes	No	3	9	7
351	b.b19x6	b.l17x3	12.0478	No	Yes	3	9	9
352	b.b20x4	b.l17x3	15.9858	Yes	Yes	3	8	9
353	b.l17x4	b.l19x2	6.85764	No	Yes	0	3	9
354	b.l17x5	b.l19x2	3.41472	No	Yes	0	6	9
355	b.b19x4	b.l17x7	4.22222	Yes	No	3	8	7
356	b.b18x1	b.l19x1	8.76958	No	Yes	2	9	9
357	b.b18x3	b.b19x2	4.09875	Yes	Yes	3	8	6
358	b.b18x3	b.b19x4	5.08778	Yes	Yes	3	8	8
359	b.b18x5	b.l18x4	2.76069	Yes	No	0	5	7
360	b.l18x1	b.l18x2	10.4319	Yes	Yes	8	6	7
361	b.b22x5	b.l18x1	8.66417	Yes	Yes	8	7	6
362	b.l18x1	b.l22x4	3.07486	Yes	No	8	6	9
363	b.l18x1	g.h2x8	5.78486	Yes	No	0	6	7
364	b.l18x1	g.h2x11	4.21333	Yes	Yes	8	6	6
365	b.l18x2	g.h2x11	4.55611	Yes	Yes	8	7	6
366	b.l18x3	b.l18x5	8.40042	No	No	0	5	2
367	b.b19x2	b.b20x6	10.1221	Yes	Yes	3	6	6
368	b.b19x2	b.l20x1	3.09625	Yes	No	0	6	6
369	b.b19x3	b.b22x5	3.25347	No	Yes	0	4	7
370	b.b19x4	b.b20x6	6.84542	Yes	Yes	3	8	6
371	b.b19x5	b.l21x9	4.14028	No	No	0	5	6
372	b.b19x6	b.l19x2	5.45958	No	Yes	3	9	9
373	b.b20x2	b.l19x2	8.27069	No	Yes	0	6	9
374	b.b20x2	b.b20x4	7.22403	No	Yes	0	6	8
375	b.b20x3	b.b21x7	4.25667	No	Yes	0	8	5
376	b.b20x3	b.l21x9	4.29833	No	No	0	8	6
377	b.b20x4	b.b20x6	3.20917	Yes	Yes	3	8	6
378	b.b20x4	b.b21x3	12.7433	Yes	Yes	3	8	6
379	b.b20x4	b.b21x6	8.69625	Yes	No	3	8	1
380	b.b20x5	b.b21x4	3.51722	No	No	0	7	5
381	b.b20x5	b.b21x7	3.77625	No	Yes	0	7	5
382	b.b20x6	b.b21x3	6.76903	Yes	Yes	3	6	6
383	b.b20x7	b.l20x2	2.79431	Yes	Yes	0	9	9
384	b.b20x7	b.l20x3	3.64486	Yes	No	0	9	7
385	b.b20x7	b.b21x4	5.55986	Yes	No	0	9	5
386	b.b20x7	g.h2x4	3.0875	Yes	No	0	9	7
387	b.l20x2	g.l1x5	6.64667	Yes	No	0	9	4
388	b.b21x3	b.b21x6	4.11417	Yes	No	3	6	1
389	b.b21x5	b.b21x7	7.83306	Yes	Yes	0	4	5
390	b.b21x5	b.b25x1	2.75042	Yes	No	0	4	2
391	b.b21x7	b.b23x2	6.6275	Yes	No	0	5	6
392	b.b21x7	b.b24x6	10.3428	Yes	Yes	0	5	8
393	b.l21x2	b.l21x4	9.79486	Yes	No	0	4	4
394	b.l21x2	b.l21x5	3.12889	Yes	Yes	0	4	4
395	b.b23x6	b.l21x5	4.28069	Yes	Yes	9	7	4
396	b.l21x7	b.l23x2	5.05639	No	Yes	0	5	8
397	b.b23x6	b.l21x9	9.15069	Yes	No	0	7	6
398	b.b22x2	b.b26x3	6.34069	No	Yes	0	8	6
399	b.b22x4	b.b26x3	3.10528	No	Yes	0	5	6
400	b.b22x4	b.b26x5	3.72708	No	No	0	5	7
401	b.b22x5	b.b23x2	6.44417	Yes	No	0	7	6
402	b.l22x1	g.ctx3	6.56292	No	Yes	0	9	9
403	b.l22x3	g.ctx3	8.60889	No	Yes	0	9	9
404	b.b24x7	b.l22x5	13.0513	No	Yes	13	9	9
405	b.l22x5	b.l24x2	6.29236	Yes	No	0	9	6
406	b.l22x5	g.h2x12	3.11444	Yes	No	0	9	7
407	b.l22x5	g.ctx6	3.8775	Yes	Yes	13	9	6
408	b.b23x1	b.b24x5	3.78708	No	No	0	5	5
409	b.b23x3	b.b24x5	4.01472	No	No	0	7	5
410	b.b23x3	b.b26x3	2.90139	No	Yes	0	7	6
411	b.b23x3	b.b27x1	4.42861	No	No	0	7	6
412	b.b23x4	b.b23x6	3.89236	No	Yes	0	6	7
413	b.b23x6	b.b24x4	11.5638	Yes	Yes	9	7	6
414	b.b23x6	b.b24x6	7.07472	Yes	Yes	9	7	8
415	b.l23x1	b.l25x6	15.8999	Yes	No	2	6	8
416	b.b24x2	b.l23x2	7.23583	No	Yes	0	5	8
417	b.b24x1	b.l25x5	2.86972	No	No	0	4	7
418	b.b24x3	b.b25x7	6.10806	No	No	0	5	7
419	b.b24x4	b.b24x6	3.57833	Yes	Yes	9	6	8
420	b.b24x4	b.b25x3	7.41569	Yes	No	9	6	5
421	b.b24x4	b.b25x6	4.12389	Yes	No	0	6	3
422	b.b24x6	b.b25x3	4.625	Yes	No	9	8	5
423	b.b24x7	b.l24x3	6.01139	No	Yes	0	9	5
424	b.b25x2	b.l24x3	4.705	No	Yes	0	2	5
425	b.b25x7	b.b28x6	16.6724	No	Yes	0	7	9
426	b.l25x3	b.l25x7	3.38389	Yes	No	0	9	7
427	b.b27x3	b.l25x3	5.66736	No	Yes	0	8	9
428	b.b27x5	b.l25x3	13.6558	No	Yes	7	9	9
429	b.l25x3	b.l27x2	8.69917	Yes	Yes	7	9	9
430	b.b28x4	b.l25x3	8.73333	Yes	Yes	7	6	9
431	b.l25x4	b.l27x2	7.42861	No	Yes	0	5	9
432	8x56	b.l25x4	3.67819	No	No	0	7	5
433	b.l25x6	b.l27x1	22.0068	No	Yes	2	8	9
434	b.b26x1	b.l27x1	6.14222	No	Yes	0	9	9
435	b.b26x3	b.b27x3	3.25458	Yes	No	0	6	8
436	b.l26x1	b.l26x3	6.52597	No	No	20	7	7
437	b.l26x3	b.l26x5	8.23986	No	No	0	7	5
438	b.l26x5	g.ctx4	4.88917	No	No	0	5	7
439	b.l26x5	g.ctx15	4.30903	No	No	0	5	9
440	b.l26x6	g.ctx16	3.8125	No	Yes	0	7	8
441	b.b27x3	b.b28x6	8.20347	No	Yes	0	8	9
442	b.b27x5	b.l27x2	7.56597	No	Yes	7	9	9
443	b.b28x2	b.l27x2	9.90292	No	Yes	0	4	9
444	b.b28x4	b.b28x6	6.28333	Yes	Yes	7	6	9
445	b.b28x5	g.ctx16	4.11583	No	Yes	6	5	8
446	b.b28x7	g.ctx14	7.28347	No	Yes	6	9	9
447	b.b28x7	g.ctx16	3.03667	No	Yes	6	9	8
448	g.h1x10	g.h1x14	7.32764	No	No	0	9	9
449	g.l1x2	g.l1x4	7.04639	No	Yes	0	2	8
450	g.h2x3	g.l1x5	3.53472	No	No	0	5	4
451	g.h2x2	g.l1x6	3.97375	No	No	22	9	4
452	g.h2x3	g.h2x7	3.66986	No	No	0	5	5
453	g.h2x11	g.h2x15	15.425	Yes	No	0	6	6
454	g.ctx3	g.ctx4	3.6225	Yes	No	0	9	7
455	g.ctx3	g.ctx6	7.29389	Yes	Yes	0	9	6
456	g.ctx10	g.ctx9	3.26333	No	No	0	5	6
457	g.ctx14	g.ctx15	6.02194	Yes	No	0	9	9
458	g.ctx14	g.ctx16	4.12819	Yes	Yes	6	9	8
459	1x39	2x61	3.36222	No	No	0	5	8
460	1x46	1x50	3.08917	No	Yes	0	8	9
461	1x46	2x54	3.59514	No	No	0	8	9
462	1x46	7x47	4.04778	No	No	0	8	8
463	1x50	2x47	3.23528	Yes	No	0	9	9
464	1x50	2x50	11.5564	Yes	Yes	0	9	9
465	1x50	7x50	8.8475	Yes	No	0	9	9
466	1x52	8x54	7.62833	No	No	0	8	8
467	1x54	2x47	3.04625	No	No	0	8	9
468	1x57	2x40	4.01875	No	Yes	0	8	9
469	1x57	2x44	4.89611	No	No	0	8	7
470	1x60	I1x50	6.65875	No	No	0	8	9
471	I1x48	I1x51	6.32431	No	No	0	8	7
472	2x40	I1x50	4.13764	Yes	No	23	9	9
473	8x50	I1x50	9.60847	Yes	No	23	8	9
474	2x37	2x39	2.84472	No	No	0	8	9
475	2x37	2x40	4.30708	No	Yes	0	8	9
476	2x39	3x49	5.39417	No	Yes	16	9	9
477	2x39	I2x57	5.88875	No	Yes	16	9	7
478	2x40	8x50	5.30222	Yes	Yes	23	9	8
479	2x41	4x42	3.09625	No	No	0	8	8
480	2x42	3x46	3.67569	Yes	No	0	8	9
481	2x42	4x42	4.77931	Yes	No	0	8	8
482	2x42	4x45	4.04792	Yes	No	0	8	7
483	2x42	4x46	3.24972	Yes	No	0	8	8
484	2x45	3x42	7.46681	No	Yes	1	9	8
485	2x45	4x46	5.83875	No	No	0	9	8
486	2x45	4x50	4.32431	No	Yes	1	9	9
487	2x46	3x42	3.71208	Yes	Yes	1	9	8
488	2x46	3x43	3.71069	Yes	No	1	9	8
489	2x46	7x49	6.67708	Yes	Yes	1	9	9
490	2x50	7x46	8.19972	Yes	No	0	9	9
491	2x52	3x35	7.13958	No	Yes	0	8	7
492	2x53	3x35	4.01	No	Yes	0	8	7
493	2x53	7x46	4.56125	No	No	0	8	9
494	2x56	3x32	7.30708	No	No	1	8	8
495	2x56	7x42	4.20417	No	Yes	1	8	8
496	2x57	2x58	3.2425	No	No	1	8	9
497	2x59	3x28	7.33875	No	Yes	0	7	7
498	2x60	3x28	3.68042	No	Yes	0	8	7
499	2x63	E1x50	3.21833	No	Yes	0	8	8
500	2x64	7x35	4.45417	No	No	0	7	7
501	2x66	E1x49	2.73944	No	No	0	7	5
502	E1x50	E1x52	7.24	Yes	No	0	8	7
503	3x25	E1x50	6.00375	No	Yes	24	9	8
504	E1x50	E2x50	8.90694	Yes	No	24	8	9
505	E1x51	E1x52	6.06125	No	No	0	5	7
506	3x24	E1x52	3.655	Yes	No	0	6	7
507	3x25	E2x50	6.97667	No	No	24	9	9
508	3x32	7x42	8.23861	No	Yes	1	8	8
509	3x32	Lig	14.4464	No	Yes	1	8	0
510	3x33	4x57	3.49958	No	No	0	8	8
511	3x33	Lig	9.27028	No	Yes	0	8	0
512	3x34	4x53	2.89625	Yes	No	0	7	8
513	3x34	4x57	7.13264	Yes	No	0	7	8
514	3x36	6x48	6.37292	No	Yes	0	7	9
515	3x36	Lig	8.02806	No	Yes	0	7	0
516	3x37	4x53	3.46667	No	No	0	8	8
517	3x38	4x50	9.01347	No	Yes	0	8	9
518	3x38	4x53	3.08833	No	No	0	8	8
519	3x40	6x44	4.20361	No	Yes	1	9	9
520	3x40	6x48	7.8125	No	Yes	1	9	9
521	3x41	4x49	3.95889	No	No	0	7	8
522	3x42	4x49	4.13583	Yes	No	0	8	8
523	3x43	7x49	5.32069	No	Yes	1	8	9
524	3x43	7x53	6.41542	No	Yes	1	8	9
525	3x46	3x50	3.71528	No	Yes	1	9	9
526	3x47	5x58	7.10333	No	Yes	1	9	8
527	3x48	3x52	6.58986	No	No	0	7	6
528	3x49	I2x53	7.1375	Yes	Yes	16	9	9
529	3x49	I2x57	6.50486	Yes	Yes	16	9	7
530	3x51	3x55	12.9806	Yes	No	0	8	7
531	3x52	I2x53	7.07458	No	Yes	0	6	9
532	3x53	I2x53	4.22083	No	Yes	0	9	9
533	I2x53	I2x57	9.46944	Yes	Yes	16	9	7
534	4x38	4x41	3.08542	No	No	0	8	8
535	4x58	4x59	2.86625	No	Yes	0	6	8
536	5x36	E2	4.18181	No	Yes	1	5	7
537	5x47	6x52	20.1503	Yes	Yes	1	8	8
538	5x54	5x58	3.42292	No	Yes	1	8	8
539	6x35	6x39	3.57458	No	No	0	7	7
540	6x36	7x56	6.8825	No	No	0	8	8
541	6x40	7x53	3.75153	No	Yes	0	8	9
542	6x43	7x52	4.18847	No	No	0	8	8
543	6x44	6x48	3.20139	Yes	Yes	1	9	9
544	6x45	6x49	2.92014	No	Yes	0	7	7
545	6x47	7x45	6.33944	No	No	0	8	9
546	6x48	6x51	3.27111	Yes	Yes	1	9	8
547	6x48	6x52	6.59972	Yes	Yes	1	9	8
548	6x48	7x41	8.40417	Yes	No	0	9	8
549	6x48	7x45	8.45931	Yes	No	0	9	9
550	6x49	6x50	3.38375	Yes	No	0	7	9
551	6x49	6x53	3.86292	Yes	No	0	7	7
552	6x50	7x37	7.45708	No	Yes	0	9	7
553	6x51	6x52	5.40375	Yes	Yes	1	8	8
554	6x51	6x55	5.79792	Yes	Yes	1	8	8
555	6x51	7x38	11.2686	Yes	No	1	8	7
556	6x51	Lig	9.45208	Yes	Yes	1	8	0
557	6x54	7x34	3.51792	No	Yes	0	7	6
558	6x54	7x37	3.93208	No	Yes	0	7	7
559	6x55	Lig	5.85389	Yes	Yes	1	8	0
560	7x33	7x37	3.54083	No	Yes	0	7	7
561	7x38	7x42	11.6161	No	Yes	1	7	8
562	7x38	Lig	15.1394	No	Yes	1	7	0
563	7x39	7x42	5.25264	Yes	Yes	0	7	8
564	7x42	Lig	6.24708	Yes	Yes	1	8	0
565	7x45	7x49	7.92653	No	Yes	0	9	9
566	7x52	7x53	4.68556	No	Yes	0	8	9
567	7x54	8x50	9.40417	No	Yes	0	9	8
568	7x54	8x54	4.69639	No	No	0	9	8
569	7x55	7x56	3.03583	Yes	No	0	7	8
570	8x47	8x49	4.99319	No	No	0	9	8
571	8x47	8x50	6.77611	No	Yes	0	9	8
572	G.HN.40	b.b5x3	2.98556	No	Yes	0	7	9
573	G.S1.01	G.S3.04	4.51181	No	Yes	0	6	6
574	G.H1.07	G.H5.03	3.465	No	Yes	0	9	8
575	G.H5.05	G.s2s3.01	2.79056	Yes	No	12	5	4
576	G.H2.05	b.l17x6	6.39819	No	Yes	0	7	9
577	G.H2.06	b.l15x1	3.50333	Yes	No	2	9	7
578	G.H2.06	b.b18x1	4.97528	Yes	No	2	9	9
579	G.H3.17	G.h2s4.02	4.88333	Yes	Yes	2	4	7
580	G.h2s4.02	b.l27x1	4.52403	Yes	Yes	2	7	9
581	G.S4.05	G.S5.07	3.59222	No	No	0	7	9
582	G.S4.07	G.s5hg.01	3.84125	No	No	0	8	9
583	G.H3.03	G.H3.07	3.39042	No	No	0	4	5
584	G.H3.09	G.H3.13	3.09681	Yes	Yes	4	9	5
585	G.H3.13	G.h4s6.02	5.26736	Yes	Yes	0	5	7
586	G.S5.05	G.s6h5.01	3.27903	Yes	Yes	11	9	9
587	G.HG.04	G.HG.08	3.38264	Yes	No	0	8	7
588	G.H4.03	G.HG.04	2.70792	No	Yes	0	3	8
589	G.H4.03	G.HG.05	3.92125	No	No	0	3	4
590	G.HG.17	G.hgh4.01	4.06847	No	No	0	3	4
591	G.hgh4.03	G.hgh4.04	5.48042	No	No	0	6	5
592	G.H4.07	G.S6.05	6.13153	No	Yes	4	4	5
593	G.H4.12	G.S6.05	3.73861	Yes	Yes	4	5	5
594	G.H5.14	G.S6.02	4.17778	No	Yes	0	6	8
595	G.s6h5.01	G.s6h5.05	3.39333	Yes	No	11	9	9
596	G.H5.03	G.s6h5.01	7.20944	Yes	Yes	11	8	9
597	G.H5.03	G.s6h5.05	3.44125	Yes	No	11	8	9
598	G.H5.05	G.H5.08	3.44319	Yes	Yes	12	5	8
599	5x68	G.H5.13	5.05847	No	No	0	7	7
600	5x68	G.H5.16	5.17889	No	No	0	7	7
601	5x68	G.H5.17	4.33833	No	Yes	0	7	5
602	6x33	G.H5.25	3.31208	No	Yes	0	8	6
603	6x37	G.H5.25	4.24917	Yes	Yes	0	8	6
604	b.1x11	g.h1x11	4.69972	No	Yes	0	8	9
605	b.1x13	b.1x17	2.97222	No	No	0	1	2
606	b.1x19	b.b21x1	10.0069	No	Yes	0	6	7
607	b.1x19	b.b21x2	4.575	No	No	0	6	6
608	b.b21x2	b.lh12x1	3.41306	No	No	0	6	3
609	b.lh12x2	g.l1x6	7.56708	No	No	22	8	4
610	b.h2x5	b.lhb1x3	3.54667	No	Yes	0	5	2
611	b.l24x3	b.lhb1x3	2.84639	Yes	Yes	0	5	2
612	b.b1x1	b.lhb1x10	5.07819	No	No	0	5	4
613	b.b2x1	b.l27x1	6.15056	Yes	Yes	2	8	9
614	b.b3x1	b.l2x3	4.39153	No	No	0	5	8
615	b.b3x3	b.b6x3	2.89444	Yes	No	0	8	8
616	b.b10x3	b.b6x2	3.28611	No	No	0	8	8
617	b.b8x1	b.b9x4	3.48347	No	No	0	8	9
618	b.b8x2	b.b8x4	5.30028	No	Yes	0	8	6
619	b.b8x5	b.l8x3	5.56403	No	No	0	4	3
620	b.b10x2	b.b10x4	4.21722	No	No	0	6	6
621	b.b12x7	b.l10x4	4.88083	No	No	21	9	3
622	b.b12x5	b.b13x5	3.49958	Yes	No	0	6	4
623	b.b13x3	b.b13x6	3.62208	No	No	0	4	4
624	b.b16x7	b.l14x6	2.73222	No	No	0	9	3
625	b.b17x5	g.l1x2	3.12611	Yes	No	0	7	2
626	b.b19x4	b.l17x3	7.03417	Yes	Yes	3	8	9
627	b.l17x3	b.l19x2	3.27333	Yes	Yes	3	9	9
628	b.l17x5	b.l19x1	2.88139	No	Yes	0	6	9
629	b.l17x6	b.l19x1	3.84264	Yes	Yes	2	9	9
630	b.l18x1	b.l18x3	6.47903	Yes	No	8	6	5
631	b.b22x5	b.l18x2	3.10778	Yes	Yes	8	7	7
632	b.l18x2	b.l22x4	2.79125	Yes	No	8	7	9
633	b.l18x3	g.h2x11	11.5807	No	Yes	8	5	6
634	b.l18x5	b.l20x2	10.4114	No	Yes	0	2	9
635	b.b20x2	b.l21x1	3.08889	No	No	0	6	2
636	b.l20x2	g.h2x7	4.53389	Yes	No	0	9	5
637	b.b25x3	b.l21x2	2.80653	No	Yes	0	5	4
638	b.l21x5	b.l23x2	3.94472	Yes	Yes	9	4	8
639	b.l21x7	b.l23x1	3.09069	No	Yes	0	5	6
640	b.b22x1	b.l23x1	3.29486	No	Yes	0	8	6
641	b.b23x6	b.l23x2	4.36042	Yes	Yes	9	7	8
642	b.l25x5	b.l27x1	6.93694	No	Yes	0	7	9
643	g.h1x12	g.h1x9	3.69486	No	No	0	6	6
644	g.ctx2	g.h2x15	2.97333	No	No	0	3	6
645	g.ctx10	g.ctx13	3.05583	No	No	0	5	5
646	1x43	2x57	3.90333	No	No	1	7	8
647	1x43	2x58	3.10542	No	No	1	7	9
648	8x49	I1x49	4.64361	No	No	0	8	7
649	2x38	4x39	3.19708	No	No	0	7	6
650	2x42	3x45	3.76931	Yes	No	0	8	8
651	2x42	3x49	5.34181	Yes	Yes	0	8	9
652	2x46	2x50	4.50569	Yes	Yes	1	9	9
653	2x50	3x39	3.10653	Yes	No	0	9	9
654	2x50	7x49	6.33889	Yes	Yes	1	9	9
655	2x56	3x28	4.26667	No	Yes	0	8	7
656	2x60	7x42	2.80833	No	Yes	0	8	8
657	3x31	3x35	3.87875	No	Yes	0	7	7
658	3x34	3x35	2.96944	Yes	Yes	0	7	7
659	3x37	4x56	3.47806	No	No	0	8	8
660	3x37	5x461	7.76944	No	No	0	8	0
661	3x40	5x50	3.24875	No	Yes	0	9	6
662	3x42	4x50	4.23208	Yes	Yes	1	8	9
663	3x44	5x50	2.83167	No	Yes	0	7	6
664	3x44	5x53	3.42833	No	No	0	7	5
665	3x46	7x53	3.41847	No	Yes	1	9	9
666	3x47	5x54	2.77264	No	No	1	9	8
667	3x47	5x57	3.13958	No	No	0	9	5
668	3x50	5x58	4.51472	Yes	Yes	1	9	8
669	3x50	7x53	5.09986	Yes	Yes	1	9	9
670	3x51	3x52	3.39097	Yes	No	0	8	6
671	3x51	5x57	6.64222	Yes	No	0	8	5
672	3x51	5x60	7.98722	Yes	No	0	8	4
673	3x56	I2x52	4.3725	No	No	0	7	6
674	E2	E2x51	6.48903	Yes	No	0	7	4
675	E2x52	Lig	9.39278	No	Yes	1	7	0
676	5x39	E2	6.37389	Yes	Yes	1	5	7
677	5x39	5x43	9.46778	Yes	No	0	5	7
678	5x40	6x55	4.41042	No	Yes	0	8	8
679	5x43	Lig	4.45819	No	Yes	0	7	0
680	5x44	6x52	3.83708	Yes	Yes	1	9	8
681	5x44	6x56	3.32972	Yes	No	1	9	7
682	5x461	Lig	4.17972	No	Yes	0	0	0
683	5x47	5x48	6.15694	Yes	Yes	1	8	9
684	5x47	5x51	7.49583	Yes	No	1	8	9
685	5x47	6x44	5.67208	Yes	Yes	1	8	9
686	5x47	6x48	3.2575	Yes	Yes	1	8	9
687	5x47	6x49	5.47569	Yes	Yes	0	8	7
688	5x51	6x44	3.76222	No	Yes	1	9	9
689	5x54	6x44	6.32389	No	Yes	1	8	9
690	5x58	6x37	4.70514	Yes	Yes	0	8	8
691	5x58	6x40	4.71014	Yes	No	0	8	8
692	5x58	6x41	3.29028	Yes	No	0	8	7
693	5x62	5x66	6.38333	No	No	0	9	8
694	5x62	6x34	6.24889	No	No	0	9	8
695	5x62	6x37	3.1225	No	Yes	0	9	8
696	5x65	6x33	2.75917	No	No	0	7	8
697	6x51	7x34	5.51486	Yes	Yes	1	8	6
698	6x52	Lig	4.65764	Yes	Yes	1	8	0
699	6x53	6x57	2.70556	No	No	0	7	7
700	6x55	7x34	2.99	Yes	Yes	1	8	6
701	6x58	E3	5.16583	No	Yes	1	5	5
702	G.S1.04	G.S3.05	2.74444	No	Yes	0	7	6
703	G.S1.07	G.S3.08	3.04208	No	No	0	9	9
704	G.S2.06	G.S3.05	3.44681	Yes	Yes	0	8	6
705	G.H2.03	b.l13x6	4.15028	No	Yes	2	9	9
706	G.S4.02	G.h3s5.03	3.69167	Yes	No	4	7	8
707	G.HG.14	G.HG.16	2.75208	No	No	0	5	4
708	b.l5x4	b.l5x5	4.25667	No	Yes	0	8	9
709	b.b21x1	g.l1x4	5.98847	Yes	Yes	0	7	8
710	g.h1x5	g.h1x9	2.81014	No	No	0	6	6
711	1x39	7x39	6.78417	No	Yes	0	5	7
712	1x53	7x54	3.745	No	No	0	9	9
713	4x59	5x39	3.11167	Yes	Yes	1	8	5
714	E2	E2	35.7608	Yes	Yes	1	7	7
715	5x36	5x38	4.00972	No	No	0	5	5
716	5x44	5x48	2.99806	Yes	Yes	1	9	9
717	5x44	6x55	3.56569	Yes	Yes	1	9	8
718	5x48	6x56	4.42986	Yes	No	1	9	7
719	5x69	6x26	3.62333	No	No	0	8	5
720	E3	E3	3.16583	Yes	Yes	1	5	5
721	7x36	7x40	3.43458	No	No	0	6	8
722	G.H2.06	b.l19x1	2.93792	Yes	Yes	2	9	9
723	b.b10x1	b.l9x6	3.44333	No	Yes	0	9	8
724	3x28	E1x50	6.78611	Yes	Yes	0	7	8
725	4x60	5x39	4.82694	No	Yes	1	8	5
726	E2	E2x52	3.20111	Yes	No	1	7	7
727	4x39	G.HN.52	3.5875	No	No	0	6	4
728	G.H1.01	G.S3.07	3.41861	No	No	17	9	9
729	G.H2.08	G.H3.18	3.51833	No	Yes	0	8	9
730	G.s4h3.02	G.s5hg.01	3.25125	No	No	18	9	9
731	G.H3.09	G.h4s6.01	4.02833	Yes	No	0	9	4
732	G.H3.09	G.S6.01	3.32931	Yes	No	0	9	5
733	G.H3.17	b.l25x6	11.2239	Yes	No	2	4	8
734	G.H3.17	b.l27x1	2.80139	Yes	Yes	2	4	9
735	b.lh12x2	g.h2x2	4.51778	No	No	22	8	9
736	b.b2x1	b.b6x1	4.47292	Yes	No	0	8	9
737	b.b15x3	b.l13x7	3.00833	No	No	5	9	9
738	3x30	4x58	3.91125	No	No	0	8	6
739	3x41	5x50	2.92125	No	Yes	0	7	6
740	4x59	4x60	3.02833	Yes	No	1	8	8
741	G.HN.36	b.b5x2	5.44583	No	Yes	0	4	7
742	g.ctx14	g.ctx17	3.56708	Yes	Yes	0	9	7
743	E1x49	E1x51	3.68125	No	No	0	5	5
744	G.HN.30	G.HN.34	2.96972	Yes	Yes	0	8	3
745	G.h4s6.04	G.h4s6.10	3.23333	No	No	0	0	3
746	G.H5.12	I2x50	3.14194	No	No	0	7	9
747	G.H5.17	G.H5.26	2.7875	Yes	No	0	5	5
748	b.1x1	b.1x5	2.73167	No	No	0	0	3
749	b.1x2	b.1x5	3.64056	No	No	0	0	3
750	b.1x2	b.1x6	2.75667	No	No	0	0	3
751	b.b1x3	g.ctx17	7.19583	No	Yes	0	7	7
752	b.b20x6	b.l17x3	3.5825	Yes	Yes	3	6	9
753	1x60	8x56	3.34583	No	No	0	8	7
754	3x21	3x24	5.9975	No	Yes	0	7	6
755	3x30	4x61	3.7925	No	No	0	8	7
756	3x56	I2x53	3.345	No	Yes	0	7	9
757	4x58	4x62	3.24417	No	No	0	6	5
758	6x61	E3	4.39833	No	Yes	0	3	5
759	G.hns1.01	b.l1x4	2.86611	No	No	0	3	6
760	G.H2.01	b.l13x6	3.27528	Yes	Yes	2	9	9
761	G.H3.17	b.l23x1	3.07083	Yes	Yes	2	4	6
762	I1x49	b.l25x4	5.22667	No	No	0	7	5
763	G.HN.51	G.hns1.02	2.75083	No	No	0	4	4
764	G.S1.03	G.hns1.01	5.31611	No	No	0	9	3
765	G.S1.02	I2x51	3.59056	No	Yes	0	4	7
766	G.H2.01	G.H2.03	4.74889	Yes	No	2	9	9
767	G.H3.13	G.h4s6.13	10.9314	Yes	No	0	5	0
768	G.H4.07	G.HG.01	3.16417	No	No	4	4	5
769	G.H4.10	G.hgh4.08	4.12583	Yes	Yes	0	6	1
770	G.H4.13	G.hgh4.08	4.02222	No	Yes	0	2	1
771	G.H4.08	G.H4.12	3.68667	Yes	Yes	0	3	5
772	G.H5.17	G.h4s6.20	4.05806	Yes	No	25	5	0
773	5x72	G.h4s6.20	3.15194	No	No	25	0	0
774	G.H5.17	G.S6.02	4.7275	Yes	Yes	0	5	8
775	G.H5.10	G.S6.04	4.37667	No	No	0	7	8
776	5x72	G.H5.17	2.71333	No	Yes	25	0	5
777	3x28	Lig	3.02639	Yes	Yes	0	7	0
778	4x63	E2	2.90917	No	Yes	0	0	7
779	4x64	E2	4.58083	No	Yes	1	0	7
780	G.HG.15	G.s4h3.04	3.44611	No	Yes	0	7	8
781	G.H4.13	I3	3.51167	No	No	0	2	0
782	G.H4.02	G.hgh4.21	2.94444	No	No	0	5	0
783	G.h4s6.10	G.h4s6.12	3.11028	No	No	0	3	4
784	5x66	6x30	2.7	No	No	0	8	9
785	6x36	G.H5.25	2.69319	No	Yes	0	8	6
786	b.b25x5	b.lhb1x8	2.69	No	No	0	4	2
787	G.H5.15	G.H5.19	2.68319	No	No	0	8	8
788	6x58	7x34	2.68319	No	Yes	1	5	6
789	5x37	6x60	2.68236	No	No	0	6	5
790	b.b12x5	b.b13x4	2.68194	Yes	No	0	6	4
791	b.1x12	b.1x16	2.68042	No	No	0	6	4
792	b.b26x4	b.b2x5	2.67556	No	Yes	0	5	7
793	b.1x7	g.h1x8	2.67458	No	No	0	8	7
794	G.H3.16	G.h3s5.01	2.66583	No	No	0	4	2
795	b.b18x2	b.b22x3	2.66278	No	No	0	5	6
796	1x50	2x51	2.65361	Yes	No	0	9	8
797	G.HG.02	G.s6h5.02	2.63597	No	No	0	9	7
798	G.HG.07	G.s4h3.02	2.635	No	No	0	9	9
799	g.ctx12	g.ctx13	2.635	No	No	0	6	5
800	g.ctx7	g.ctx8	2.625	No	No	0	4	8
801	b.1x11	b.1x14	2.6225	No	No	0	8	4
802	b.b15x4	b.l17x7	2.6225	No	No	0	6	7
803	G.H4.03	G.H4.04	2.61875	No	No	0	3	4
804	1x45	7x47	2.61583	No	No	0	5	8
805	G.H5.02	G.s6h5.04	2.60917	No	No	0	4	8
806	1x55	8x57	2.58903	No	No	0	7	8
807	b.h2x1	g.h2x5	2.58472	No	No	0	5	6
808	G.HN.43	b.b5x6	2.57042	No	No	0	8	6
809	b.l16x2	b.l16x3	2.56778	No	No	0	9	3
810	5x55	6x41	2.54069	No	No	0	9	7
811	b.b16x3	b.b19x2	2.54	No	Yes	0	6	6
812	2x49	4x50	2.53625	No	Yes	0	8	9
813	G.H5.11	G.S3.03	2.53514	No	Yes	0	8	7
814	G.H4.14	G.H4.17	2.53361	Yes	No	0	6	3
815	b.l7x5	b.l9x1	2.52556	No	No	0	6	5
816	b.l22x2	g.ctx3	2.51639	No	Yes	0	1	9
817	G.H4.04	G.hgh4.20	2.50917	No	No	0	4	0
818	G.H4.01	G.hgh4.21	2.50444	No	No	0	3	0
819	2x57	7x42	2.49917	No	Yes	1	8	8
820	b.l21x8	b.l23x1	2.49056	No	Yes	0	4	6
821	G.HN.46	G.HN.50	2.48056	No	No	0	4	5
822	G.H3.02	G.H4.11	2.47917	No	No	0	8	8
823	b.b15x5	b.l15x2	2.46597	No	No	0	8	9
824	3x29	E2x52	2.46319	No	No	0	7	7
825	b.b15x1	b.l16x1	2.45625	Yes	No	0	9	4
826	1x49	7x50	2.45292	No	No	0	9	9
827	G.H5.18	G.H5.21	2.45069	No	No	0	4	4
828	G.h4s6.02	G.h4s6.11	2.44917	Yes	No	0	7	8
829	b.l22x2	b.l26x4	2.44444	No	No	0	1	9
830	7x30	E3	2.43167	No	Yes	1	7	5
831	b.b23x5	b.l25x7	2.42778	No	No	0	7	7
832	b.l17x1	b.l17x2	2.42667	No	No	0	2	6
833	2x64	7x39	2.41556	No	Yes	0	7	7
834	G.S5.07	G.s1h1.06	2.405	No	No	0	9	9
835	1x42	7x39	2.39056	No	Yes	0	7	7
836	4x56	5x46	2.38278	No	No	0	8	6
837	2x551	3x31	2.37306	No	No	0	7	7
838	G.HN.26	G.HN.30	2.37167	No	Yes	0	0	8
839	g.h1x11	g.h1x7	2.36944	Yes	No	0	9	2
840	8x47	8x48	2.36847	No	No	0	9	6
841	1x52	8x57	2.36542	No	No	0	8	8
842	5x49	5x50	2.36167	No	Yes	0	7	6
843	G.HN.46	G.HN.49	2.35444	No	No	0	4	4
844	G.hgh4.05	G.hgh4.07	2.35417	Yes	No	0	6	8
845	b.l20x3	g.h2x1	2.33444	No	No	0	7	8
846	b.b17x2	b.l16x3	2.32944	No	No	0	3	3
847	5x45	5x48	2.32444	No	Yes	0	7	9
848	2x41	4x43	2.31014	No	No	0	8	6
849	b.b18x4	b.b22x5	2.30722	No	Yes	0	3	7
850	3x22	E2	2.30667	No	Yes	0	4	7
851	G.H4.11	G.H4.15	2.30292	No	Yes	0	8	8
852	g.ctx14	g.ctx9	2.29958	Yes	No	0	9	6
853	b.1x6	b.1x9	2.28347	No	No	0	3	4
854	5x69	6x29	2.27708	No	No	0	8	8
855	b.b7x4	b.b7x5	2.25944	Yes	No	0	8	9
856	3x26	4x64	2.2575	No	No	0	7	0
857	1x56	8x54	2.25292	No	No	0	9	8
858	1x48	1x49	2.24708	No	No	0	5	9
859	G.HG.02	G.HG.03	2.24431	No	Yes	0	9	6
860	G.s4h3.05	G.s4h3.06	2.23083	No	No	0	9	8
861	G.hfs2.06	G.hfs2.07	2.22	No	No	0	8	8
862	3x54	5x64	2.20028	No	No	0	8	6
863	b.b19x1	b.l18x1	2.19597	No	Yes	0	6	6
864	2x43	8x50	2.18806	No	Yes	0	8	8
865	1x52	8x58	2.17083	No	No	0	8	8
866	I1x48	b.l1x1	2.17028	No	No	0	8	7
867	5x37	6x59	2.16639	No	No	0	6	7
868	2x38	G.hns1.03	2.1625	No	No	0	7	4
869	b.b2x2	b.b6x3	2.15903	No	No	0	7	8
870	b.b9x2	b.l12x1	2.14333	No	No	0	5	6
871	b.b27x4	b.b28x3	2.1375	No	Yes	0	5	7
872	2x55	2x551	2.13569	No	No	0	6	7
873	G.H4.02	G.hgh4.08	2.13083	No	Yes	0	5	1
874	b.1x10	b.1x14	2.13	No	No	0	1	4
875	1x36	2x61	2.11375	No	No	0	6	8
876	b.l26x2	b.l2x2	2.10792	No	No	0	1	1
877	6x43	7x48	2.09917	No	No	0	8	7
878	7x30	7x32	2.09778	No	No	0	7	5
879	G.HG.09	G.HG.12	2.09458	No	No	0	1	2
880	G.s6h5.02	G.s6h5.04	2.09125	No	No	0	7	8
881	2x38	I2x57	2.08556	No	Yes	0	7	7
882	b.1x15	g.h1x15	2.07556	No	No	0	7	8
883	5x71	G.H5.13	2.07417	No	No	0	7	7
884	1x51	2x51	2.0525	No	No	0	6	8
885	b.1x3	b.ntx3	2.05167	No	No	0	1	0
886	G.hns1.02	I2x54	2.04417	No	No	0	4	7
887	b.b18x4	b.b22x3	2.04208	No	No	0	3	6
888	G.S4.01	G.S5.03	2.03	No	No	0	8	8
889	b.b10x5	b.b6x4	2.02069	Yes	No	0	9	7
890	G.hgh4.08	G.hgh4.11	2.00778	Yes	No	0	1	0
891	G.s1h1.02	G.s1h1.05	1.995	No	No	0	7	9
892	G.s1h1.03	G.s1h1.04	1.98056	No	No	0	7	8
893	3x54	5x61	1.97681	No	No	0	8	7
894	5x40	6x59	1.97667	No	No	0	8	7
895	g.ctx6	g.ctx7	1.96403	Yes	No	0	6	4
896	G.h3s5.02	G.h4s6.10	1.9575	No	No	0	4	3
897	G.s3h2.01	G.s3h2.02	1.93417	No	No	0	9	9
898	G.s1h1.05	G.s1h1.06	1.93292	No	No	0	9	9
899	G.HN.37	G.HN.41	1.93208	No	No	0	2	4
900	b.b28x1	b.b28x2	1.92583	No	No	0	4	4
901	b.b8x5	b.b9x1	1.92458	No	No	0	4	4
902	b.b13x1	b.b9x2	1.91806	No	No	0	4	5
903	g.h2x3	g.l1x6	1.91708	No	No	0	5	4
904	6x39	7x52	1.91153	No	No	0	7	8
905	g.h2x14	g.h2x15	1.88833	No	No	0	4	6
906	G.H2.04	G.H3.11	1.8675	No	No	0	9	7
907	5x60	5x63	1.85375	No	No	0	4	8
908	b.1x11	g.h1x12	1.84083	No	No	0	8	6
909	G.H4.01	G.HG.14	1.83333	No	No	0	3	5
910	g.h1x12	g.h1x8	1.81681	No	No	0	6	7
911	b.1x4	g.h1x4	1.79486	No	No	0	8	5
912	7x55	8x51	1.78028	Yes	No	0	7	9
913	b.1x22	g.l1x4	1.77903	No	Yes	0	3	8
914	G.HN.48	G.HN.51	1.77111	No	No	0	4	4
915	b.1x3	b.1x7	1.74833	No	No	0	1	8
916	b.lhb1x3	g.h2x9	1.74222	Yes	Yes	0	2	4
917	b.b17x2	g.h1x13	1.72389	No	No	0	3	1
918	b.1x12	g.h1x11	1.68417	No	Yes	0	6	9
919	g.h1x13	g.h1x9	1.68292	No	No	0	1	6
920	5x41	6x59	1.67764	No	No	0	7	7
921	1x60	8x53	1.67569	No	No	0	8	8
922	b.l13x1	b.l13x2	1.66833	No	No	0	2	6
923	G.H1.05	G.S2.04	1.65319	No	No	0	7	7
924	5x64	5x67	1.63722	No	No	0	6	8
925	4x48	4x52	1.63667	No	No	0	5	7
926	G.hgh4.17	G.hgh4.18	1.61528	No	No	0	0	0
927	G.h4s6.08	G.h4s6.09	1.605	No	No	0	5	4
928	G.s4h3.07	G.s4h3.15	1.60042	No	No	0	4	9
929	5x56	5x60	1.58847	No	No	0	6	4
930	G.H3.04	G.H3.07	1.57375	No	No	0	9	5
931	G.hns1.03	I2x55	1.57333	No	No	0	4	6
932	7x36	7x37	1.56208	No	Yes	0	6	7
933	g.ctx11	g.ctx17	1.555	No	Yes	0	4	7
934	G.HN.39	b.b5x5	1.55292	No	Yes	0	4	5
935	G.HN.34	G.HN.37	1.5475	Yes	No	0	3	2
936	b.b21x3	b.l17x2	1.52347	Yes	No	0	6	6
937	b.h2x4	g.h2x9	1.51986	No	Yes	0	3	4
938	1x55	1x59	1.51861	No	No	0	7	7
939	b.b12x1	b.l13x5	1.51667	No	No	0	6	5
940	4x38	4x39	1.51375	No	No	0	8	6
941	g.h2x13	g.h2x9	1.50389	No	Yes	0	1	4
942	G.H5.01	G.H5.02	1.49722	No	No	0	8	4
943	b.l4x2	g.ctx21	1.46167	Yes	No	0	4	0
944	b.b21x7	b.l24x1	1.46069	Yes	No	0	5	5
945	G.hgh4.10	G.hgh4.11	1.45833	No	No	0	0	0
946	G.H4.04	G.hgh4.16	1.45667	No	No	0	4	0
947	G.HG.13	G.s4h3.04	1.44917	No	Yes	0	6	8
948	1x36	2x65	1.445	No	Yes	0	6	7
949	G.H2.01	b.b12x1	1.4375	Yes	No	0	9	6
950	G.HG.03	G.HG.06	1.41944	Yes	No	0	6	5
951	8x48	8x52	1.41042	No	No	0	6	6
952	G.HN.31	G.HN.34	1.39569	No	Yes	0	3	3
953	4x38	4x40	1.38833	No	No	0	8	5
954	3x34	4x54	1.38111	Yes	No	0	7	7
955	G.H5.22	G.H5.23	1.365	No	No	0	4	4
956	b.l26x2	b.l2x4	1.34792	No	No	0	1	5
957	I2x52	I2x56	1.33583	No	No	0	6	6
958	G.HN.11	G.HN.33	1.32542	No	No	0	3	4
959	G.H1.11	G.S2.05	1.325	No	No	2	0	3
960	G.H1.11	G.S3.02	1.325	No	Yes	2	0	3
961	b.l25x2	b.l25x3	1.32458	No	Yes	0	5	9
962	1x47	2x55	1.30792	No	No	0	7	6
963	b.b24x2	b.l25x1	1.30208	No	No	0	5	3
964	5x55	5x59	1.28833	No	No	0	9	9
965	1x54	1x58	1.28792	No	No	0	8	6
966	G.H4.06	G.HG.04	1.28625	No	Yes	0	7	8
967	b.b25x4	b.lhb1x6	1.27417	No	Yes	0	4	3
968	b.lh12x3	g.h2x1	1.27208	No	No	0	4	8
969	1x42	7x43	1.27111	No	No	0	7	7
970	2x62	E1x51	1.26431	No	No	0	7	5
971	b.1x13	b.1x9	1.25847	No	No	0	1	4
972	b.l8x4	b.l8x5	1.24264	No	No	0	3	3
973	b.lhb1x2	b.lhb1x3	1.23931	No	Yes	0	1	2
974	8x51	8x55	1.22444	No	No	0	9	6
975	G.H4.08	G.hgh4.14	1.18611	Yes	No	0	3	0
976	b.l24x3	b.lhb1x5	1.18528	Yes	No	0	5	1
977	3x23	3x24	1.1725	No	Yes	0	5	6
978	6x41	6x42	1.17167	No	No	0	7	7
979	G.H4.02	G.HG.09	1.17028	No	No	0	5	1
980	G.S2.07	G.s2s3.02	1.16806	No	No	0	3	4
981	G.HN.27	G.HN.28	1.15472	No	No	0	0	0
982	6x31	6x35	1.15083	No	No	0	7	7
983	b.b20x1	b.l21x5	1.14972	No	Yes	0	5	4
984	b.l8x5	b.l8x7	1.14931	No	No	0	3	3
985	1x29	1x31	1.12333	No	Yes	0	0	5
986	1x31	1x35	1.12083	Yes	No	0	5	6
987	b.l8x3	b.l8x6	1.11222	No	No	0	3	4
988	b.b16x1	b.l17x3	1.095	No	Yes	0	4	9
989	6x27	6x30	1.09167	No	No	0	6	9
990	4x40	4x44	1.08194	No	No	0	5	3
991	b.1x18	g.l1x4	1.07417	No	Yes	0	4	8
992	b.lhb1x6	b.lhb1x7	1.07333	Yes	No	0	3	1
993	g.ctx1	g.ctx2	1.06875	No	No	0	1	3
994	b.l21x2	b.l21x3	1.0675	Yes	No	0	4	3
995	b.b21x5	b.h2x2	1.06444	Yes	No	0	4	1
996	G.H4.08	G.hgh4.13	1.05333	Yes	No	0	3	0
997	5x75	I3	1.03444	No	No	0	0	0
998	6x32	G.H5.24	1.03306	No	No	0	9	8
999	1x35	2x65	1.02333	No	Yes	0	6	7
1000	G.H1.03	G.s1h1.06	1.01111	No	No	0	9	9
1001	3x41	4x52	1.00528	No	No	0	7	7
1002	G.HN.45	G.HN.49	0.994167	No	No	0	4	4
1003	1x54	2x48	0.992778	No	No	0	8	7
1004	G.HN.29	G.HN.33	0.991111	No	No	0	0	4
1005	5x73	I3	0.983333	No	No	0	0	0
1006	7x31	7x32	0.970833	No	No	0	4	5
1007	5x74	5x75	0.969445	No	No	0	0	0
1008	g.h1x3	g.h1x7	0.969167	No	No	0	3	2
1009	3x24	3x27	0.94375	Yes	No	0	6	6
1010	1x32	2x65	0.943056	No	Yes	0	4	7
1011	G.H1.06	G.H5.03	0.932778	No	Yes	0	9	8
1012	5x76	G.h4s6.03	0.916111	No	No	0	0	4
1013	G.H3.01	G.s4h3.08	0.860417	Yes	No	0	9	0
1014	g.ctx6	g.h2x16	0.855833	Yes	No	0	6	4
1015	G.H1.02	G.H1.03	0.844445	No	No	0	9	9
1016	G.HN.30	G.HN.32	0.838333	Yes	No	0	8	5
1017	b.1x8	g.h1x11	0.811944	No	Yes	0	5	9
1018	7x55	G.H5.24	0.808333	Yes	No	0	7	8
1019	5x52	5x56	0.80625	No	No	0	7	6
1020	7x51	7x55	0.785417	No	Yes	0	7	7
1021	1x31	1x34	0.77	Yes	No	0	5	3
1022	G.H4.08	G.hgh4.15	0.763056	Yes	No	0	3	0
1023	g.l1x3	g.l1x5	0.758333	No	No	0	1	4
1024	b.1x16	b.1x20	0.756667	No	No	0	4	2
1025	G.HG.16	G.hgh4.06	0.754167	No	No	0	4	2
1026	G.HN.38	G.HN.42	0.740417	No	No	0	3	4
1027	g.h1x3	g.h1x6	0.730417	No	No	0	3	4
1028	G.H1.09	G.H1.10	0.7275	No	No	0	7	0
1029	G.HN.37	b.b5x2	0.716111	No	Yes	0	2	7
1030	6x28	6x32	0.703333	No	No	0	5	9
1031	G.s4h3.11	G.s4h3.14	0.693333	No	No	0	0	0
1032	1x41	1x45	0.6925	No	No	0	5	5
1033	4x55	4x59	0.691667	No	Yes	0	6	8
1034	G.H2.01	G.s3h2.02	0.6875	Yes	No	0	9	9
1035	G.H1.03	G.s6h5.03	0.676667	No	No	0	9	9
1036	1x40	1x43	0.655417	No	No	0	6	7
1037	1x35	1x38	0.64375	No	No	0	6	5
1038	G.HN.34	G.HN.38	0.6375	Yes	No	0	3	3
1039	g.h1x2	g.h1x3	0.633333	No	No	0	2	3
1040	g.h1x1	g.h1x5	0.625833	No	No	0	2	6
1041	8x58	8x59	0.595417	No	No	0	8	6
1042	G.hfs2.05	G.hfs2.06	0.58875	No	No	0	9	8
1043	1x44	1x47	0.585139	No	No	0	6	7
1044	4x47	4x51	0.553611	No	No	0	5	5
1045	1x30	1x31	0.545417	No	Yes	0	4	5
1046	g.h1x15	g.l1x1	0.520833	No	No	0	8	1
1047	5x70	5x71	0.515833	No	No	0	5	7
1048	b.1x2	b.ntx2	0.490833	No	No	0	0	0
1049	G.H1.08	G.H1.09	0.48	No	No	0	8	7
1050	G.HN.53	G.S1.01	0.47	No	No	0	2	6
1051	G.hgh4.12	G.hgh4.13	0.469444	No	No	0	0	0
1052	6x46	6x47	0.444583	No	No	0	5	8
1053	G.s4h3.08	G.s4h3.10	0.441667	No	No	0	0	0
1054	G.H4.05	G.hgh4.09	0.430833	No	No	0	4	0
1055	b.1x3	b.ntx1	0.425	No	No	0	1	0
1056	G.s4h3.12	G.s4h3.13	0.4225	No	No	0	0	0
1057	2x66	2x67	0.416667	No	No	0	7	6
1058	G.H3.04	G.s4h3.14	0.41125	No	No	0	9	0
1059	1x33	2x65	0.395	No	Yes	0	5	7
1060	g.h1x1	g.ntx1	0.3875	No	No	0	2	0
1061	6x25	G.h4s6.09	0.385	No	No	0	4	4
1062	g.h2x6	g.h2x7	0.385	No	No	0	2	5
1063	g.ctx12	g.ctx19	0.3825	No	No	0	6	0
1064	G.s4h3.07	G.s4h3.13	0.356667	No	No	0	4	0
1065	8x59	CT	0.3475	No	No	0	6	0
1066	G.HN.35	G.HN.38	0.335417	No	No	0	3	3
1067	G.hgh4.17	G.hgh4.20	0.3175	No	No	0	0	0
1068	G.HN.10	G.HN.11	0.307083	No	No	0	3	3
1069	4x51	4x55	0.304167	No	No	0	5	6
1070	G.s4h3.09	G.s4h3.10	0.251667	No	No	0	0	0
1071	6x37	6x38	0.2375	Yes	No	0	8	7
1072	G.HN.26	G.HN.27	0.235	No	No	0	0	0
1073	b.l21x6	b.l21x7	0.227778	No	No	0	3	5
1074	G.HG.10	G.HG.11	0.216667	No	No	0	0	0
1075	5x38	5x42	0.205833	No	No	0	5	7
1076	1x31	NT	0.202083	Yes	No	0	5	5
1077	b.lh12x5	g.h2x5	0.197083	No	No	0	0	6
1078	6x24	6x25	0.1875	No	No	0	6	4
1079	G.hgh4.17	G.hgh4.19	0.182222	No	No	0	0	0
1080	1x34	1x37	0.146667	No	No	0	3	5
1081	G.HG.11	G.HG.14	0.145	No	No	0	0	5
1082	g.ctx17	g.ctx18	0.0966667	Yes	No	0	7	0
1083	g.h2x10	g.h2x9	0.0670833	No	Yes	0	3	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.30	2.44177	4	0	8
2	G.HN.34	1.6376	4	0	3
3	G.S1.06	4.04667	4	17	8
4	G.S2.06	6.17764	4	0	8
5	G.S2.08	4.77747	4	12	5
6	G.S3.02	5.5175	4	2	3
7	G.S3.03	6.44833	4	0	7
8	G.S3.04	5.68286	5	2	6
9	G.S3.05	3.89618	4	0	6
10	G.S3.06	7.21375	5	2	6
11	G.H2.01	2.53729	4	2	9
12	G.H2.06	5.04234	6	2	9
13	G.H2.07	5.48803	5	2	9
14	G.h2s4.01	6.23708	5	2	9
15	G.h2s4.02	5.32628	4	2	7
16	G.S4.02	4.5301	4	4	7
17	G.s4h3.04	3.62979	4	0	8
18	G.H3.01	3.41847	4	0	9
19	G.H3.09	4.44996	7	4	9
20	G.H3.13	5.56507	4	4	5
21	G.H3.17	6.62315	6	2	4
22	G.H3.18	4.37937	4	4	9
23	G.S5.04	4.22882	4	4	9
24	G.S5.05	3.369	6	11	9
25	G.HG.03	3.02851	4	18	6
26	G.HG.04	3.93757	4	0	8
27	G.hgh4.02	3.80156	4	19	8
28	G.hgh4.05	7.61288	4	0	6
29	G.hgh4.08	3.54481	5	0	1
30	G.H4.08	1.67229	4	0	3
31	G.H4.10	8.51976	4	19	6
32	G.H4.12	4.85455	4	4	5
33	G.H4.14	4.6951	4	19	6
34	G.H4.15	4.80011	5	4	8
35	G.h4s6.02	3.9833	4	0	7
36	G.S6.02	5.31692	5	0	8
37	G.S6.05	5.23174	4	4	5
38	G.s6h5.01	4.6683	4	11	9
39	G.H5.03	3.91928	5	11	8
40	G.H5.05	3.19344	4	12	5
41	G.H5.08	5.48576	4	12	8
42	G.H5.17	3.72494	5	25	5
43	G.H5.25	3.19378	5	0	6
44	b.lhb1x3	2.34365	4	0	2
45	b.lhb1x6	2.60345	6	13	3
46	b.l1x3	8.12511	5	10	9
47	b.l1x6	8.14956	5	2	9
48	b.b2x1	6.09528	5	2	8
49	b.b2x5	5.88549	6	0	7
50	b.b3x3	3.66939	5	0	8
51	b.l3x1	7.03281	4	2	9
52	b.l3x2	4.63233	4	0	9
53	b.b4x3	4.68521	4	14	7
54	b.b4x6	9.35336	6	10	9
55	b.l4x2	8.62325	5	6	4
56	b.b5x2	5.60191	4	0	7
57	b.b5x3	5.49581	6	10	9
58	b.b5x5	4.21639	4	0	5
59	b.b5x7	5.66417	4	0	7
60	b.l5x1	4.08553	5	14	8
61	b.l5x5	7.08639	6	2	9
62	b.b6x5	4.12142	5	0	6
63	b.l6x5	5.5866	4	15	4
64	b.b7x1	5.42729	4	15	4
65	b.b7x4	3.73302	4	14	8
66	b.b8x4	4.87192	5	14	6
67	b.l9x3	6.31935	6	2	9
68	b.l9x6	4.28363	10	2	8
69	b.b10x5	4.14867	5	0	9
70	b.b11x4	5.44226	4	2	9
71	b.l11x2	6.55286	5	2	9
72	b.b12x5	3.66604	4	0	6
73	b.b12x6	7.01895	7	2	8
74	b.b13x7	7.1185	5	5	7
75	b.l13x3	6.75425	5	5	9
76	b.l13x6	4.33736	5	2	9
77	b.b15x1	5.46958	5	5	9
78	b.b15x2	5.46632	4	3	6
79	b.b16x4	10.0554	4	5	6
80	b.b16x5	3.85618	4	0	5
81	b.b16x6	7.8463	6	5	8
82	b.b17x5	5.63333	4	3	7
83	b.b17x7	7.23479	4	3	8
84	b.l17x3	7.02143	7	3	9
85	b.l17x6	6.86288	4	2	9
86	b.b18x3	4.41517	4	3	8
87	b.b18x5	4.87837	4	0	5
88	b.l18x1	5.83488	7	8	6
89	b.l18x2	5.22177	4	8	7
90	b.b19x2	5.80037	6	3	6
91	b.b19x4	5.7974	4	3	8
92	b.l19x1	4.60788	4	2	9
93	b.l19x2	5.45519	5	3	9
94	b.b20x4	9.57172	5	3	8
95	b.b20x6	6.44787	6	3	6
96	b.b20x7	3.77163	4	0	9
97	b.l20x2	6.09656	4	0	9
98	b.b21x1	7.16854	4	3	7
99	b.b21x3	6.2875	4	3	6
100	b.b21x5	4.29559	4	0	4
101	b.b21x7	5.71616	6	0	5
102	b.l21x2	4.19944	4	0	4
103	b.l21x5	3.12601	4	9	4
104	b.b22x5	4.75536	5	8	7
105	b.l22x5	5.91019	5	13	9
106	b.b23x6	6.72044	6	9	7
107	b.l23x1	5.56936	5	2	6
108	b.l23x2	5.14934	4	9	8
109	b.b24x4	6.67042	4	9	6
110	b.b24x6	6.40521	4	9	8
111	b.l24x3	3.68701	4	0	5
112	b.l25x3	6.9107	6	7	9
113	b.b26x3	3.90049	4	0	6
114	b.l27x1	9.01024	8	2	9
115	b.l27x2	8.39917	4	7	9
116	b.b28x3	3.41972	4	0	7
117	b.b28x4	7.22135	4	7	6
118	b.b28x6	10.1731	4	7	9
119	g.h1x11	2.39132	4	0	9
120	g.l1x4	3.97201	4	0	8
121	g.h2x9	1.20826	4	0	4
122	g.h2x11	8.94378	4	8	6
123	g.ctx3	5.72092	5	0	9
124	g.ctx6	3.38597	5	13	6
125	g.ctx14	4.66006	5	6	9
126	g.ctx16	4.69401	7	6	8
127	g.ctx17	3.10365	4	0	7
128	1x31	0.752333	5	0	5
129	1x50	5.87639	5	0	9
130	2x40	4.44142	4	23	9
131	2x42	4.14396	6	0	8
132	2x46	4.65139	4	1	9
133	2x50	6.74144	5	1	9
134	2x65	0.951597	4	0	7
135	E1x50	6.43103	5	24	8
136	3x24	2.94219	4	0	6
137	3x28	5.01967	5	0	7
138	3x34	3.59486	4	0	7
139	3x35	4.49944	4	0	7
140	3x42	4.8867	4	1	8
141	3x49	6.09458	4	16	9
142	3x50	6.33024	4	1	9
143	3x51	7.75024	4	0	8
144	I2x51	4.82389	4	0	7
145	I2x53	6.24947	5	16	9
146	I2x57	5.98715	4	16	7
147	4x50	5.02653	4	1	9
148	4x59	2.42448	4	1	8
149	E2	11.2849	9	1	7
150	5x39	5.94507	4	1	5
151	5x44	3.43264	4	1	9
152	5x47	8.03472	6	1	8
153	5x48	3.97733	4	1	9
154	5x50	2.84083	4	0	6
155	5x58	4.62442	6	1	8
156	6x37	3.07858	4	0	8
157	6x44	4.63264	5	1	9
158	6x48	5.92233	8	1	9
159	6x49	3.91062	4	0	7
160	6x51	6.78472	6	1	8
161	6x52	8.12969	5	1	8
162	6x55	4.52358	5	1	8
163	E3	3.6655	5	1	5
164	7x34	3.67649	4	1	6
165	7x37	4.12302	4	0	7
166	7x39	4.21073	4	0	7
167	7x42	5.83802	7	1	8
168	7x49	6.5658	4	1	9
169	7x53	4.67417	5	1	9
170	7x55	1.60247	4	0	7
171	8x50	6.65581	5	23	8
172	Lig	7.84599	12	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b3x6	b.l1x3	53.4587	11.2164	No	Yes	0	9	9
2	b.b3x6	b.l3x2	53.4301	6.03208	No	Yes	0	9	9
3	b.b4x6	b.l1x3	52.0969	4.085	Yes	Yes	10	9	9
4	b.l1x4	b.l3x2	53.2052	4.20542	No	Yes	0	6	9
5	G.hns1.01	b.l1x4	53.0632	2.86611	No	No	0	3	6
6	G.S1.03	G.hns1.01	53.0413	5.31611	No	No	0	9	3
7	b.l2x5	b.l4x2	45.9722	21.8074	No	Yes	0	5	4
8	b.l4x2	g.ctx15	46.2984	10.7229	Yes	No	0	4	9
9	b.l26x5	g.ctx15	48.3037	4.30903	No	No	0	5	9
10	b.l26x5	g.ctx4	99.7128	4.88917	No	No	0	5	7
11	g.ctx3	g.ctx4	99.7467	3.6225	Yes	No	0	9	7
12	g.ctx3	g.ctx6	99.9154	7.29389	Yes	Yes	0	9	6
13	b.lhb1x6	g.ctx6	99.0626	2.93861	Yes	Yes	13	3	6
14	b.lhb1x6	b.lhb1x9	99.8435	2.88111	Yes	No	0	3	3
15	b.lhb1x11	b.lhb1x9	99.875	3.05847	No	No	0	4	3
16	b.b25x7	b.lhb1x11	99.9376	5.79194	No	No	0	7	4
17	b.b25x7	b.b28x6	100	16.6724	No	Yes	0	7	9
18	b.b27x3	b.b28x6	50.0397	8.20347	No	Yes	0	8	9
19	b.b27x3	b.l25x3	49.9809	5.66736	No	Yes	0	8	9
20	b.l25x3	b.l27x2	99.4445	8.69917	Yes	Yes	7	9	9
21	b.l25x4	b.l27x2	99.4742	7.42861	No	Yes	0	5	9
22	8x56	b.l25x4	97.849	3.67819	No	No	0	7	5
23	1x60	8x56	97.8034	3.34583	No	No	0	8	7
24	1x60	I1x50	97.6993	6.65875	No	No	0	8	9
25	2x40	I1x50	96.511	4.13764	Yes	No	23	9	9
26	2x37	2x40	96.9877	4.30708	No	Yes	0	8	9
27	2x37	2x39	96.9342	2.84472	No	No	0	8	9
28	2x39	3x49	83.8769	5.39417	No	Yes	16	9	9
29	3x49	I2x53	12.7092	7.1375	Yes	Yes	16	9	9
30	3x53	I2x53	23.8297	4.22083	No	Yes	0	9	9
31	3x53	G.H5.19	23.6383	5.75528	No	No	0	9	8
32	G.H5.15	G.H5.19	23.4468	2.68319	No	No	0	8	8
33	G.H5.15	I2x50	23.2552	2.87333	No	No	0	8	9
34	b.b28x4	b.b28x6	49.9509	6.28333	Yes	Yes	7	6	9
35	b.b28x4	b.l25x3	49.7577	8.73333	Yes	Yes	7	6	9
36	2x39	I2x57	13.0037	5.88875	No	Yes	16	9	7
37	I2x53	I2x57	12.268	9.46944	Yes	Yes	16	9	7
38	G.S1.03	G.S3.06	52.0552	4.37472	No	Yes	2	9	6
39	G.H5.16	I2x50	14.3976	3.23569	No	No	0	7	9
40	5x68	G.H5.16	14.2035	5.17889	No	No	0	7	7
41	G.S3.06	G.h2s4.01	17.2122	2.91792	Yes	Yes	2	6	9
42	G.S1.05	G.h2s4.01	17.2645	11.0612	No	Yes	0	9	9
43	G.S1.05	G.S4.02	17.0341	6.08528	No	Yes	0	9	7
44	G.H4.10	G.H4.14	11.7209	8.17639	Yes	Yes	19	6	6
45	G.H3.06	G.H4.14	15.6335	3.77944	No	Yes	0	7	6
46	G.H3.09	G.S5.02	15.3939	4.58542	Yes	No	4	9	6
47	G.S4.02	G.S5.02	16.4575	4.09847	Yes	No	4	7	6
48	G.S3.06	b.l5x5	35.4385	13.5029	Yes	Yes	2	6	9
49	b.l2x3	b.l2x5	44.622	4.03403	No	No	0	8	5
50	b.b3x1	b.l2x3	44.5711	4.39153	No	No	0	5	8
51	b.b3x1	b.b6x5	44.5206	3.19028	No	Yes	0	5	6
52	b.b2x4	b.b6x5	41.8657	3.11861	No	Yes	0	6	6
53	b.b10x4	b.b2x4	41.809	11.4564	No	No	0	6	6
54	b.b10x2	b.b10x4	40.7967	4.21722	No	No	0	6	6
55	b.b10x2	b.b14x3	37.2401	2.90958	No	No	0	6	5
56	b.b11x5	b.b14x3	36.0427	4.71139	No	No	0	6	5
57	b.b10x1	b.b11x5	35.919	2.92042	No	No	0	9	6
58	b.b10x1	b.l9x6	35.867	3.44333	No	Yes	0	9	8
59	G.H2.06	b.l9x6	24.6798	2.86889	Yes	Yes	2	9	8
60	b.l1x6	b.l27x1	14.5388	19.8883	Yes	Yes	2	9	9
61	b.l1x6	b.l3x1	21.9319	4.97319	Yes	Yes	2	9	9
62	b.l3x1	b.l5x5	36.7333	6.31444	Yes	Yes	2	9	9
63	b.b2x1	b.l27x1	30.9662	6.15056	Yes	Yes	2	8	9
64	b.b2x1	b.l3x1	14.6399	12.2447	Yes	Yes	2	8	9
65	G.H3.17	b.l27x1	22.3444	2.80139	Yes	Yes	2	4	9
66	3x46	3x50	33.6922	3.71528	No	Yes	1	9	9
67	2x42	3x46	61.3089	3.67569	Yes	No	0	8	9
68	2x42	3x49	72.5545	5.34181	Yes	Yes	0	8	9
69	G.H2.06	b.l19x1	24.2255	2.93792	Yes	Yes	2	9	9
70	b.l17x5	b.l19x1	24.2494	2.88139	No	Yes	0	6	9
71	b.l17x5	b.l19x2	24.1471	3.41472	No	Yes	0	6	9
72	b.l17x3	b.l19x2	23.0663	3.27333	Yes	Yes	3	9	9
73	b.b16x5	b.l14x6	17.9022	3.94125	Yes	No	0	5	3
74	b.b16x7	b.l14x6	17.4629	2.73222	No	No	0	9	3
75	b.b16x7	b.l16x3	16.584	7.81347	No	No	0	9	3
76	b.b17x2	b.l16x3	14.8255	2.32944	No	No	0	3	3
77	b.b17x2	g.h1x13	14.3857	1.72389	No	No	0	3	1
78	g.h1x13	g.h1x9	13.9459	1.68292	No	No	0	1	6
79	g.h1x12	g.h1x9	12.2266	3.69486	No	No	0	6	6
80	b.b20x6	b.l17x3	16.5485	3.5825	Yes	Yes	3	6	9
81	b.b19x2	b.b20x6	10.1458	10.1221	Yes	Yes	3	6	6
82	G.H3.17	b.l23x1	28.424	3.07083	Yes	Yes	2	4	6
83	b.l21x7	b.l23x1	48.0663	3.09069	No	Yes	0	5	6
84	b.l21x7	b.l23x2	46.8047	5.05639	No	Yes	0	5	8
85	b.b23x6	b.l23x2	41.1116	4.36042	Yes	Yes	9	7	8
86	b.b23x6	b.b24x6	36.0522	7.07472	Yes	Yes	9	7	8
87	b.b21x7	b.b24x6	34.7979	10.3428	Yes	Yes	0	5	8
88	b.l25x6	b.l27x1	21.8045	22.0068	No	Yes	2	8	9
89	b.l23x1	b.l25x6	21.5341	15.8999	Yes	No	2	6	8
90	b.b3x2	b.b4x6	51.5165	4.71542	No	Yes	0	5	9
91	b.b2x5	b.b3x2	51.551	9.85458	Yes	No	0	7	5
92	b.b2x5	b.l26x1	51.2772	11.4544	Yes	No	0	7	7
93	b.l26x1	b.l26x3	51.1469	6.52597	No	No	20	7	7
94	b.l26x3	b.l26x5	51.4372	8.23986	No	No	0	7	5
95	b.b6x1	b.l9x6	16.7964	4.48861	No	Yes	0	9	8
96	b.b2x1	b.b6x1	16.5935	4.47292	Yes	No	0	8	9
97	b.b21x7	b.b23x2	15.2219	6.6275	Yes	No	0	5	6
98	b.b22x5	b.b23x2	14.5883	6.44417	Yes	No	0	7	6
99	b.b20x5	b.b21x7	13.3195	3.77625	No	Yes	0	7	5
100	b.b20x5	b.b21x4	12.6853	3.51722	No	No	0	7	5
101	b.b20x7	b.b21x4	12.0517	5.55986	Yes	No	0	9	5
102	1x39	7x39	12.9198	6.78417	No	Yes	0	5	7
103	7x39	7x42	17.6047	5.25264	Yes	Yes	0	7	8
104	6x48	6x51	20.6489	3.27111	Yes	Yes	1	9	8
105	6x44	6x48	24.2213	3.20139	Yes	Yes	1	9	9
106	5x54	6x44	32.637	6.32389	No	Yes	1	8	9
107	5x54	5x58	31.0338	3.42292	No	Yes	1	8	8
108	3x50	5x58	31.9104	4.51472	Yes	Yes	1	9	8
109	7x42	Lig	19.305	6.24708	Yes	Yes	1	8	0
110	6x51	Lig	12.8751	9.45208	Yes	Yes	1	8	0
111	3x36	Lig	12.842	8.02806	No	Yes	0	7	0
112	3x36	6x48	13.0248	6.37292	No	Yes	0	7	9
113	6x52	Lig	19.4565	4.65764	Yes	Yes	1	8	0
114	6x48	6x52	13.2124	6.59972	Yes	Yes	1	9	8
115	6x48	7x45	22.982	8.45931	Yes	No	0	9	9
116	7x45	7x49	23.2359	7.92653	No	Yes	0	9	9
117	3x43	7x49	24.9616	5.32069	No	Yes	1	8	9
118	3x43	7x53	27.0039	6.41542	No	Yes	1	8	9
119	3x46	7x53	27.5457	3.41847	No	Yes	1	9	9
120	2x45	4x46	10.7682	5.83875	No	No	0	9	8
121	2x42	4x46	10.8587	3.24972	Yes	No	0	8	8
122	1x39	2x61	11.9827	3.36222	No	No	0	5	8
123	3x28	Lig	13.4858	3.02639	Yes	Yes	0	7	0
124	3x28	E1x50	10.5144	6.78611	Yes	Yes	0	7	8
125	1x36	2x61	11.0455	2.11375	No	No	0	6	8
126	1x36	2x65	10.1082	1.445	No	Yes	0	6	7

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x56	3x32	7.30708	1	No	No	8	8	2	1
2x56	7x42	4.20417	1	No	Yes	8	8	2	1
2x59	3x28	7.33875	0	No	Yes	7	7	2	1
2x60	3x28	3.68042	0	No	Yes	8	7	2	1
3x32	7x42	8.23861	1	No	Yes	8	8	1	1
3x32	Lig	14.4464	1	No	Yes	8	0	1	0
3x33	4x57	3.49958	0	No	No	8	8	1	2
3x33	Lig	9.27028	0	No	Yes	8	0	1	0
3x36	6x48	6.37292	0	No	Yes	7	9	1	2
3x36	Lig	8.02806	0	No	Yes	7	0	1	0
5x47	6x52	20.1503	1	Yes	Yes	8	8	2	1
6x48	6x51	3.27111	1	Yes	Yes	9	8	2	1
6x48	6x52	6.59972	1	Yes	Yes	9	8	2	1
6x51	6x52	5.40375	1	Yes	Yes	8	8	1	1
6x51	6x55	5.79792	1	Yes	Yes	8	8	1	1
6x51	7x38	11.2686	1	Yes	No	8	7	1	1
6x51	Lig	9.45208	1	Yes	Yes	8	0	1	0
6x55	Lig	5.85389	1	Yes	Yes	8	0	1	0
7x38	7x42	11.6161	1	No	Yes	7	8	1	1
7x38	Lig	15.1394	1	No	Yes	7	0	1	0
7x39	7x42	5.25264	0	Yes	Yes	7	8	2	1
7x42	Lig	6.24708	1	Yes	Yes	8	0	1	0
2x56	3x28	4.26667	1	No	Yes	8	7	2	1
2x60	7x42	2.80833	0	No	Yes	8	8	2	1
3x37	5x461	7.76944	0	No	No	8	0	2	1
E2x52	Lig	9.39278	1	No	Yes	7	0	1	0
5x39	E2	6.37389	1	Yes	Yes	5	7	2	2
5x39	5x43	9.46778	1	Yes	No	5	7	2	1
5x40	6x55	4.41042	0	No	Yes	8	8	2	1
5x43	Lig	4.45819	0	No	Yes	7	0	1	0
5x44	6x52	3.83708	1	Yes	Yes	9	8	2	1
5x461	Lig	4.17972	0	No	Yes	0	0	1	0
5x47	6x48	3.2575	1	Yes	Yes	8	9	2	2
6x51	7x34	5.51486	1	Yes	Yes	8	6	1	2
6x52	Lig	4.65764	1	Yes	Yes	8	0	1	0
6x55	7x34	2.99	1	Yes	Yes	8	6	1	2
E2	E2	35.7608	1	Yes	Yes	7	7	2	2
5x44	6x55	3.56569	1	Yes	Yes	9	8	2	1
3x28	E1x50	6.78611	0	Yes	Yes	7	8	1	2
E2	E2x52	3.20111	1	Yes	No	7	7	2	1
3x28	Lig	3.02639	0	Yes	Yes	7	0	1	0
2x57	7x42	2.49917	1	No	Yes	8	8	2	1
3x29	E2x52	2.46319	0	No	No	7	7	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
100.00	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
100.00	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
100.00	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
100.00	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
100.00	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
100.00	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
92.31	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
92.31	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
92.31	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
92.31	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
91.67	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
91.67	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
91.67	Single	6PRZ	S-Alprenolol	6PRZ-β₂-S-Alprenolol
91.67	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
91.67	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
91.67	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
91.67	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
91.67	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
91.67	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
91.67	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
91.67	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
91.67	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
91.67	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
91.67	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
91.67	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
91.67	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
91.67	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
91.67	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
91.67	Consensus	dopamine_on_gp	Orthosteric Ligand	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
85.71	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
85.71	Single	4LDE	BI167107	4LDE-β₂-BI167107
85.71	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
85.71	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
85.71	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
85.71	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
84.62	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
84.62	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
84.62	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
84.62	Single	6E67	BI167107	6E67-β₂-BI167107-Gs(CT)
84.62	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
84.62	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
84.62	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
84.62	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
84.62	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
84.62	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
84.62	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
84.62	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
84.62	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
84.62	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
84.62	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
84.62	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
84.62	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
84.62	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
84.62	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
83.33	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
83.33	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
83.33	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
83.33	Single	6PS5	S-Propranolol	6PS5-β₂-S-Propranolol
83.33	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
83.33	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
83.33	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
83.33	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
83.33	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8GG7	Constrained Epinephrine	8GG7-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8GGL	Constrained Epinephrine	8GGL-β₂-Constrained Epinephrine
83.33	Single	8GGM	Constrained Epinephrine	8GGM-β₂-Constrained Epinephrine
83.33	Single	8GGP	Constrained Epinephrine	8GGP-β₂-Constrained Epinephrine
83.33	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
83.33	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
83.33	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
83.33	Single	8UNL	Constrained Epinephrine	8UNL-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8UNO	Constrained Epinephrine	8UNO-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
83.33	Single	9AS3	LSD	9AS3-5-HT_2A-LSD
83.33	Single	9AS4	LSD	9AS4-5-HT_2A-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
83.33	Single	9AS5	Mescaline	9AS5-5-HT_2A-Mescaline
83.33	Single	9AS6	Mescaline	9AS6-5-HT_2A-Mescaline-chim(NtGi1-Gs-CtGq)/β1/γ2
83.33	Consensus	5ht_on_gp	Orthosteric Ligand	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
83.33	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
83.33	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
80.00	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
80.00	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
80.00	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
80.00	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
80.00	Single	8S2T	Isoprenaline	8S2T-β₁-Isoprenaline-chim(NtGi1-Gs)/β1/γ2
80.00	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
80.00	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
78.57	Single	3P0G	BI167107	3P0G-β₂-BI167107
78.57	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
78.57	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
78.57	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
78.57	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
78.57	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
78.57	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
78.57	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
78.57	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
78.57	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
78.57	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
78.57	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
78.57	Consensus	amine_on_gp	Orthosteric Ligand	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp
78.57	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
78.57	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
78.57	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
78.57	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
78.57	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
78.57	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
78.57	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
76.92	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
76.92	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
76.92	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
76.92	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
76.92	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
76.92	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
76.92	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
76.92	Single	4QKX	35V	4QKX-β₂-35V
76.92	Single	6PS1	Timolol	6PS1-β₂-Timolol
76.92	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
76.92	Single	7BU7	BI167107	7BU7-β₁-BI167107
76.92	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
76.92	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
76.92	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
76.92	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
76.92	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
76.92	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
76.92	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
76.92	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
76.92	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
76.92	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
76.92	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
76.92	Single	9PLN	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLN-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine
76.92	Single	9PLO	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLO-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine-Go/β1/γ2
76.92	Single	9PQD	(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole	9PQD-α_2a-(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole
76.92	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
76.92	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
76.92	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
76.92	Consensus	5ht5a_on	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
76.92	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
76.92	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
76.92	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
75.00	Single	6OBA	S-Alprenolol	6OBA-β₂-S-Alprenolol-GTPL11074
75.00	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
75.00	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
75.00	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
75.00	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
75.00	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
75.00	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
75.00	Single	8GGW	Constrained Epinephrine	8GGW-β₂-Constrained Epinephrine
75.00	Single	8GGZ	Constrained Epinephrine	8GGZ-β₂-Constrained Epinephrine
75.00	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
75.00	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
75.00	Single	8UNS	Constrained Epinephrine	8UNS-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
75.00	Single	8UNT	Constrained Epinephrine	8UNT-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
75.00	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
75.00	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
75.00	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
75.00	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
75.00	Consensus	gs_5ht	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2 7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2 7XT8-5-HT₄-Serotonin-Gs/β1/γ2
73.33	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
73.33	Single	3D4S	Timolol	3D4S-β₂-Timolol
73.33	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
73.33	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
73.33	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
73.33	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
73.33	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
73.33	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
73.33	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
73.33	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
73.33	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
73.33	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
73.33	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
71.43	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
71.43	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
71.43	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
71.43	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
71.43	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
71.43	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-Cmpd-15
71.43	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go/β1/γ2
71.43	Single	9K07	DSO-5a	9K07-BB₃-DSO-5a-chim(NtGi2L-Gs-CtGq)/β1/γ2
71.43	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
71.43	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
71.43	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
71.43	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
71.43	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
71.43	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
71.43	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
71.43	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
71.43	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
70.59	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
70.59	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
69.23	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
69.23	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
69.23	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
69.23	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
69.23	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
69.23	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/β1/γ2
69.23	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
69.23	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
69.23	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
69.23	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
69.23	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
69.23	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
69.23	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
69.23	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
69.23	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
69.23	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
69.23	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
69.23	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
69.23	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
69.23	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
69.23	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
69.23	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
68.75	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
68.75	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
66.67	Single	2YDV	NECA	2YDV-A_2A-NECA
66.67	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
66.67	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
66.67	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
66.67	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
66.67	Single	5G53	NECA	5G53-A_2A-NECA-Gs
66.67	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
66.67	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
66.67	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
66.67	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
66.67	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
66.67	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/β1/γ2
66.67	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/β1/γ2
66.67	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
66.67	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
66.67	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
66.67	Single	8UO4	Constrained Epinephrine	8UO4-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
66.67	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
66.67	Single	9I54	A1IZV	9I54-D₁-A1IZV-Gs/β1/γ2
66.67	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
66.67	Single	9IJE	Epinephrine	9IJE-β₃-Epinephrine-chim(NtGi1-Gs)/β1/γ2
66.67	Single	9IXJ	Histamine	9IXJ-H₂-Histamine-Gs/β1/γ2
66.67	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
66.67	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
66.67	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
66.67	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
64.71	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
64.71	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
64.29	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
64.29	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
64.29	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
64.29	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
64.29	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
64.29	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
64.29	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
64.29	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
64.29	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
64.29	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
64.29	Single	8JXR	LSD	8JXR-D₁-LSD
64.29	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-Gi1/β1/γ1
64.29	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
64.29	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
64.29	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
64.29	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
64.29	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
64.29	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
64.29	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
64.29	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
64.29	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
64.29	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
64.29	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
64.29	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
64.29	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
64.29	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
62.50	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
62.50	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
62.50	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
62.50	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
62.50	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
62.50	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
62.50	Single	9GL2	Befiradol	9GL2-5-HT_1A-Befiradol-Gs/β1/γ2
62.50	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
62.50	Consensus	5ht1a_on_gp	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
62.50	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
61.54	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
61.54	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
61.54	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
61.54	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
61.54	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
61.54	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
61.54	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
61.54	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
61.54	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
61.54	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
61.54	Single	8YUT	Amthamine	8YUT-H₂-Amthamine-Gs/β1/γ2
61.54	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
61.54	Consensus	5ht2_on_gp	Orthosteric Ligand	5ht2b_on_gp
61.54	Consensus	5ht2b_on_gp	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
61.54	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
61.54	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
61.54	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
61.54	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
61.11	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
61.11	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
61.11	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-Gi1/β1/γ1
61.11	Single	9BUY	LM189	9BUY-β₂-LM189-Gi1/β1/γ2
61.11	Single	9M4T	Silodosin	9M4T-Alpha1A-Silodosin
60.00	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
60.00	Single	5C1M	BU72	5C1M-μ-BU72
60.00	Single	6PS6	Timolol	6PS6-β₂-Timolol
60.00	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
60.00	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
60.00	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
60.00	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
60.00	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
60.00	Single	9ARY	Serotonin	9ARY-5-HT_2A-Serotonin-chim(NtGi1-Gs-CtGq)/β1/γ2
60.00	Single	9ARZ	2-bromo-LSD	9ARZ-5-HT_2A-2-bromo-LSD
60.00	Single	9DYD	Asenapine	9DYD-5-HT_1A-Asenapine-Go/β1/γ2
60.00	Single	9DYF	Asenapine	9DYF-5-HT_1A-Asenapine-Gi1/β1/γ2
60.00	Single	9I52	A1IZU	9I52-D₁-A1IZU-Gs/β1/γ2
60.00	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
60.00	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
58.82	Single	5X93	K-8794	5X93-ET_B-K-8794
58.82	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
58.82	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
58.82	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
58.82	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
58.82	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
58.82	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
58.82	Single	9AS0	2-bromo-LSD	9AS0-5-HT_2A-2-bromo-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
58.82	Single	9DYE	Buspirone	9DYE-5-HT_1A-Buspirone-Go/β1/γ2
58.33	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/β1/γ2
58.33	Single	8GH1	Constrained Epinephrine	8GH1-β₂-Constrained Epinephrine
58.33	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
57.14	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
57.14	Single	6TPG	EMPA	6TPG-OX₂-EMPA
57.14	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
57.14	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
57.14	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
57.14	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
57.14	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
57.14	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
57.14	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
57.14	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
57.14	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
57.14	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
57.14	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
57.14	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
57.14	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
57.14	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
57.14	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
57.14	Single	9ARX	Serotonin	9ARX-5-HT_2A-Serotonin
57.14	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
57.14	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
56.25	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
56.25	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
56.25	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
56.25	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
56.25	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
56.25	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
56.25	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
56.25	Single	8E0G	BU72	8E0G-μ-BU72
56.25	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
56.25	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
56.25	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
56.25	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
56.25	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
55.56	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
55.56	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
55.56	Single	8Y72	Peptide	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
55.56	Single	9MD1	Buspirone	9MD1-5-HT_1A-Buspirone-Gz/β1/γ2
53.85	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
53.85	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
53.85	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
53.85	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
53.85	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
53.85	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
53.85	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
53.85	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
53.85	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
53.85	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
53.85	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
53.85	Single	9AS2	DMT	9AS2-5-HT_2A-DMT-chim(NtGi1-Gs-CtGq)/β1/γ2
53.85	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
53.85	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
53.85	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
53.33	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
53.33	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
53.33	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
53.33	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
53.33	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
53.33	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
53.33	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
53.33	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
53.33	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
53.33	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/β1/γ2
53.33	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
53.33	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
53.33	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
53.33	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
53.33	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
53.33	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
53.33	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
53.33	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
53.33	Single	9AS1	DMT	9AS1-5-HT_2A-DMT
53.33	Single	9JEA	Atropine	9JEA-M₁-Atropine
53.33	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
53.33	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
53.33	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
53.33	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
53.33	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
53.33	Consensus	gi_orexin	Orthosteric Ligand	7SQO-OX₂-TAK-925-Gi1/β1/γ2
53.33	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
53.33	Consensus	histamine_off	Orthosteric Ligand	h1_off
52.94	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
52.94	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
52.94	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
52.94	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
52.94	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
52.94	Single	9M4Q	Doxazosin	9M4Q-Alpha1A-Doxazosin
52.94	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
52.94	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
52.94	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
52.94	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
52.94	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
52.94	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
52.94	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
52.94	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
52.94	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
52.63	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
52.63	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
52.63	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
52.63	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
50.00	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
50.00	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
50.00	Single	5WQC	EMPA	5WQC-OX₂-EMPA
50.00	Single	6AKX	A4R	6AKX-CCR5-A4R
50.00	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
50.00	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
50.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
50.00	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
50.00	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
50.00	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
50.00	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
50.00	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2
50.00	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
50.00	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
50.00	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
50.00	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
50.00	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
50.00	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
50.00	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
50.00	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
50.00	Single	8GEI	Constrained Epinephrine	8GEI-β₂-Constrained Epinephrine-Gs/β1/γ2
50.00	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
50.00	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
50.00	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
50.00	Single	8IWM	2-Phenylethylamine	8IWM-TA9-2-Phenylethylamine
50.00	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
50.00	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
50.00	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
50.00	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
50.00	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
50.00	Single	9CGJ	C6-Quino	9CGJ-δ-C6-Quino-Gi1/β1/γ2
50.00	Single	9CHU	Noradrenaline	9CHU-β₂-Noradrenaline
50.00	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
50.00	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
50.00	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go/β1/γ2
50.00	Single	9LRB	Histamine	9LRB-H₁-Histamine-Gs/β1/γ2
50.00	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
50.00	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
50.00	Consensus	endothelin_off	Orthosteric Ligand	etb_off
50.00	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
50.00	Consensus	gs_histamine	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
50.00	Consensus	h2_on	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
50.00	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
50.00	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
50.00	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
50.00	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
50.00	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
47.37	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
47.37	Single	6PT3	DPI-287	6PT3-δ-DPI-287
47.37	Single	9CGK	C5-Quino	9CGK-δ-C5-Quino-Gi1/β1/γ2
47.06	Single	4DJH	JDTic	4DJH-κ-JDTic
47.06	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
47.06	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
47.06	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
47.06	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
47.06	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
47.06	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
47.06	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
47.06	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
47.06	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
47.06	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
47.06	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
47.06	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
47.06	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
47.06	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
47.06	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
47.06	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
47.06	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
47.06	Consensus	a2_on	Orthosteric Ligand	a2b_on
47.06	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
47.06	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
47.06	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
47.06	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
47.06	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
47.06	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
47.06	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
46.67	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
46.67	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
46.67	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
46.67	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
46.67	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
46.67	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
46.67	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
46.67	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
46.67	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
46.67	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
46.67	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
46.67	Single	6VI4	JDTic	6VI4-κ-JDTic
46.67	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
46.67	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
46.67	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
46.67	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
46.67	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
46.67	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
46.67	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
46.67	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
46.67	Single	9LRD	Histamine	9LRD-H₁-Histamine-Gi1/β1/γ2
46.67	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
46.67	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
46.67	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
46.15	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
46.15	Single	6FUF	All-trans-Retinal	6FUF-Rhodopsin-All-trans-Retinal-Go
46.15	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.15	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
46.15	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
46.15	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
46.15	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
46.15	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
46.15	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
46.15	Single	9LRC	Histamine	9LRC-H₄-Histamine
46.15	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
46.15	Consensus	5ht2_on	Orthosteric Ligand	5ht2b_on
46.15	Consensus	5ht2b_on	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.15	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
46.15	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
46.15	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
45.00	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
45.00	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
44.44	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
44.44	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
44.44	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
44.44	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
44.44	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
44.44	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
43.75	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
43.75	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
43.75	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
43.75	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
43.75	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
43.75	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
43.75	Single	5DHG	C-35	5DHG-NOP-C-35
43.75	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
43.75	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
43.75	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
43.75	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
43.75	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
43.75	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
43.75	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
43.75	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
43.75	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
43.75	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
43.75	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
43.75	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
43.75	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
43.75	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
43.75	Single	8T1W	CVN424	8T1W-GPR6-CVN424
43.75	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
43.75	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
43.75	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
43.75	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
43.75	Consensus	a3_on	Orthosteric Ligand	a3a_on
43.75	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
43.75	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
43.75	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
43.48	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
42.86	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
42.86	Single	6HLL	CP99994	6HLL-NK₁-CP99994
42.86	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
42.86	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
42.86	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
42.86	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
42.86	Single	8YN2	Histamine	8YN2-H₁-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
42.86	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
42.86	Single	9AS7	Psilocin	9AS7-5-HT_2A-Psilocin
42.86	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
42.11	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
42.11	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
42.11	Single	7EZC	UKA	7EZC-A_2A-UKA
42.11	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
42.11	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
42.11	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-chim(NtGi2L-Gs-CtGq)/β1/γ2
42.11	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
42.11	Single	8ZWG	JR14a	8ZWG-C3a_B-JR14a-Gi1/β1/γ2
42.11	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
42.11	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
42.11	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
41.67	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
41.18	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
41.18	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
41.18	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
41.18	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
41.18	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
41.18	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
41.18	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
41.18	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
41.18	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
41.18	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
41.18	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
41.18	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
41.18	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
41.18	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
41.18	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
41.18	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
41.18	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
41.18	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
41.18	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
41.18	Single	9HAP	Tolvaptan	9HAP-V₂-Tolvaptan
41.18	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
41.18	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
41.18	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
40.91	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
40.91	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
40.91	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
40.91	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
40.91	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
40.00	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
40.00	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
40.00	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
40.00	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
40.00	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
40.00	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
40.00	Single	5WS3	EMPA	5WS3-OX₂-EMPA
40.00	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
40.00	Single	6B73	MP1104	6B73-κ-MP1104
40.00	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
40.00	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
40.00	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
40.00	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
40.00	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
40.00	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
40.00	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
40.00	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
40.00	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
40.00	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
40.00	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
40.00	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
40.00	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
40.00	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
40.00	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
40.00	Single	9IPV	JR14a	9IPV-C3a_B-JR14a-Gi1/β1/γ2
40.00	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
40.00	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
40.00	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
40.00	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
40.00	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
40.00	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
40.00	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
40.00	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
40.00	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
40.00	Consensus	sensory_offon	Orthosteric Ligand	sensory_off sensory_on
40.00	Consensus	sensory_offon_gp	Orthosteric Ligand	sensory_on_gp sensory_on
39.13	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
39.13	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
39.13	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
38.89	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
38.89	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
38.89	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
38.89	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
38.89	Single	6E59	L-760735	6E59-NK₁-L-760735
38.89	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
38.89	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
38.89	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
38.89	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
38.89	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
38.89	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
38.89	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
38.89	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
38.89	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
38.89	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
38.89	Single	8Y73	Peptide	8Y73-μ-Peptide-MPAM-15-Gi1/β1/γ2
38.89	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
38.89	Single	8ZWF	JR14a	8ZWF-C3a_B-JR14a
38.89	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
38.89	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
38.89	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
38.89	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
38.89	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
38.89	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
38.46	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
38.46	Single	7MTB	All-trans-Retinal	7MTB-Rhodopsin-All-trans-Retinal-GRK1
38.46	Single	8WC5	Tetramethylammonium Ion	8WC5-TA1-Tetramethylammonium Ion-chim(NtGi1-Gs)/β1/γ2
38.46	Single	9EE9	Adenosine	9EE9-A_2A-Adenosine-Gs/β1/γ2
38.46	Consensus	opsins_on	Orthosteric Ligand	rhodopsin_on opsin1lw_on
38.46	Consensus	sensory_on	Orthosteric Ligand	opsins_on
38.10	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
38.10	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
38.10	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
38.10	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
38.10	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
37.50	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
37.50	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
37.50	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
37.50	Single	6IQL	L745870	6IQL-D₄-L745870
37.50	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
37.50	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
37.50	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
37.50	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
37.50	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
37.50	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
37.50	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
37.50	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
37.50	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
37.50	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
37.50	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
37.50	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
37.50	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
37.50	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
37.50	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
37.50	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
37.50	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
37.50	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
37.50	Consensus	sensory_off	Orthosteric Ligand	opsins_off
36.84	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
36.84	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
36.84	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
36.84	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
36.84	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
36.84	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
36.84	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
36.84	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
36.84	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
36.84	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
36.84	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
36.84	Single	8JWY	2-118	8JWY-A_2A-2-118
36.84	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
36.84	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
36.84	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
36.84	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
36.84	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
36.84	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
36.84	Consensus	orexin_on	Orthosteric Ligand	ox2_on
36.84	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
36.84	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
36.84	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
36.36	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
36.36	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
35.71	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
35.71	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
35.71	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
35.71	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
35.71	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
35.71	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
35.71	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
35.71	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
35.71	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
35.71	Consensus	opsins_on_gp	Orthosteric Ligand	rhodopsin_on_gp opsin1lw_on_gp
35.71	Consensus	rhodopsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
35.71	Consensus	sensory_on_gp	Orthosteric Ligand	opsins_on_gp
35.29	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
35.29	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
35.29	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
35.29	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
35.29	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
35.29	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
35.29	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
35.29	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
35.29	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
35.29	Single	9JGK	Balovaptan	9JGK-5-HT_2B-Balovaptan
35.29	Single	9KFJ	PubChem 138319674	9KFJ-RXFP3-PubChem 138319674-Gi2/β1/γ2
35.29	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
35.29	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
35.29	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
35.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
35.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
35.00	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
35.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
35.00	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
35.00	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
35.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
35.00	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
35.00	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
35.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
35.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
35.00	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
35.00	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
35.00	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
35.00	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
35.00	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
35.00	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
34.78	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
34.78	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
34.78	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
34.78	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
34.78	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
34.78	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
34.78	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
34.78	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
34.78	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
34.62	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
34.62	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
34.62	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
34.62	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
33.33	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
33.33	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
33.33	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
33.33	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
33.33	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
33.33	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
33.33	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
33.33	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
33.33	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
33.33	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
33.33	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
33.33	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
33.33	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
33.33	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
33.33	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
33.33	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
33.33	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
33.33	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
33.33	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
33.33	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
33.33	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
33.33	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
33.33	Single	7W41	PD176252	7W41-BB₂-PD176252
33.33	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
33.33	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
33.33	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
33.33	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
33.33	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
33.33	Single	8GEJ	Constrained Epinephrine	8GEJ-β₂-Constrained Epinephrine-Gs/β1/γ2
33.33	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
33.33	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
33.33	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
33.33	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
33.33	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
33.33	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
33.33	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
33.33	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
33.33	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
33.33	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
33.33	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
33.33	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
33.33	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
33.33	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
33.33	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
33.33	Single	8ZBI	Somatostatin-14	8ZBI-SST3-Somatostatin-14-Gi1/β1/γ2
33.33	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
33.33	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
33.33	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
33.33	Single	9EHS	LUF7602	9EHS-A_3A-LUF7602
33.33	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
33.33	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
33.33	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
33.33	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
33.33	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
33.33	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
33.33	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
33.33	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
33.33	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
33.33	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
33.33	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
33.33	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
33.33	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
33.33	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
33.33	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
33.33	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
33.33	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
33.33	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
33.33	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
33.33	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
33.33	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
33.33	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
33.33	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
32.14	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
32.14	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
32.14	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
32.14	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
32.14	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
32.00	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
32.00	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
32.00	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
31.82	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
31.82	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
31.82	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
31.82	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
31.82	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
31.82	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
31.82	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
31.82	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
31.82	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
31.82	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
31.82	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
31.82	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
31.82	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
31.58	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
31.58	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
31.58	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
31.58	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
31.58	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
31.58	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
31.58	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
31.58	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
31.58	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
31.58	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
31.58	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
31.58	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
31.58	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
31.58	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
31.58	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
31.58	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
31.58	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
31.58	Single	9IK9	SST analogue	9IK9-SST1-SST analogue-Gi1/β1/γ2
31.58	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
31.58	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
31.58	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
31.25	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
31.25	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
31.25	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
31.25	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
31.25	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
31.25	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
31.25	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
31.25	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
31.25	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
31.25	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
31.25	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
31.25	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
31.25	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
31.25	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
31.25	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
31.25	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
31.25	Single	8A6C	All-trans-Retinal	8A6C-Rhodopsin-All-trans-Retinal
31.25	Single	8A6D	All-trans-Retinal	8A6D-Rhodopsin-All-trans-Retinal
31.25	Single	8A6E	All-trans-Retinal	8A6E-Rhodopsin-All-trans-Retinal
31.25	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
31.25	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
31.25	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
31.25	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
31.25	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
31.25	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
31.25	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
31.25	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
31.25	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
31.25	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
31.25	Single	9H2X	A1IR1	9H2X-A_2A-A1IR1-Na
31.25	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
31.25	Single	9K6L	SA0	9K6L-TAS2R16-SA0-Gi2/β1/γ2
31.25	Single	9KPE	SA0	9KPE-TAS2R16-SA0-Gi1/β1/γ2
31.25	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
31.25	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
31.25	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
31.25	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
31.25	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
30.77	Single	3PXO	All-trans-Retinal	3PXO-Rhodopsin-All-trans-Retinal
30.77	Single	5DYS	All-trans-Retinal	5DYS-Rhodopsin-All-trans-Retinal
30.77	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
30.77	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
30.77	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
30.77	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
30.77	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
30.77	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
30.77	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
30.43	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
30.43	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
30.43	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
30.43	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
30.43	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
30.43	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
30.43	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
30.43	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
30.43	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
30.00	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
30.00	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
30.00	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
30.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
30.00	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
30.00	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
30.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
30.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
30.00	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
30.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
30.00	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
30.00	Single	8JD3	JNJ-40411813	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
30.00	Single	9DGI	Z8526711350	9DGI-CB₁-Z8526711350
30.00	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
30.00	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
30.00	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
30.00	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
30.00	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
30.00	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
30.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
30.00	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
30.00	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
30.00	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
29.63	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
29.63	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
29.63	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
29.63	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
29.41	Single	3REY	XAC	3REY-A_2A-XAC
29.41	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
29.41	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
29.41	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
29.41	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
29.41	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
29.41	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
29.41	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
29.41	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
29.41	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
29.41	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
29.41	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
29.41	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
29.41	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
29.41	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
29.41	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
29.41	Single	7F61	PF-03654746	7F61-H₃-PF-03654746
29.41	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
29.41	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
29.41	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
29.41	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
29.41	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
29.41	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
29.41	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
29.41	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
29.41	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
29.41	Single	8K9L	Damgo	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
29.41	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
29.41	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
29.41	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
29.41	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
29.41	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
29.41	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
29.41	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
29.41	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
29.41	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
29.41	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
29.41	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
29.41	Single	9JH3	CMF-019	9JH3-Apelin-CMF-019-Gi1/β1/γ2
29.41	Consensus	a2_off	Orthosteric Ligand	a2a_off
29.41	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
29.41	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
29.41	Consensus	hca_on	Orthosteric Ligand	hca2_on
29.17	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
29.17	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
29.17	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
28.57	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
28.57	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
28.57	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
28.57	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
28.57	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
28.57	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
28.57	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
28.57	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
28.57	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
28.57	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
28.57	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
28.57	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
28.57	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
28.57	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
28.57	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
28.57	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
28.57	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
28.57	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
28.57	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
28.57	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
28.57	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
28.57	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
28.57	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
28.57	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
28.57	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
28.57	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
28.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
28.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
28.00	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
28.00	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
28.00	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
28.00	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
28.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
28.00	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
27.78	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
27.78	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
27.78	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
27.78	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
27.78	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
27.78	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
27.78	Single	5UEN	DU172	5UEN-A₁-DU172
27.78	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
27.78	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
27.78	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
27.78	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
27.78	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
27.78	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
27.78	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
27.78	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
27.78	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
27.78	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
27.78	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
27.78	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
27.78	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
27.78	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
27.78	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
27.78	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
27.78	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
27.78	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
27.78	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
27.78	Single	9H37	A1IR0	9H37-A_2A-A1IR0-Na
27.78	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
27.78	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
27.78	Consensus	blt_on	Orthosteric Ligand	blt1_on
27.78	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
27.78	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
27.78	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
27.78	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
27.78	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
27.78	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
27.78	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
27.78	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
27.78	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
27.78	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
27.59	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
27.27	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
27.27	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
27.27	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
27.27	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
27.27	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
27.27	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
27.27	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
27.27	Single	9IZA	SCH900271	9IZA-HCA₂-SCH900271-Gi1/β1/γ2
27.27	Single	9JF4	PD168368	9JF4-BB₁-PD168368
27.27	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
27.27	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
27.27	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
26.92	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
26.92	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
26.92	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
26.92	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
26.92	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
26.67	Single	3PQR	All-trans-Retinal	3PQR-Rhodopsin-All-trans-Retinal-Gt(CT)
26.67	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
26.67	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
26.67	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
26.67	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
26.67	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
26.67	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
26.67	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
26.67	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
26.67	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
26.67	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
26.67	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
26.67	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
26.67	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
26.67	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
26.67	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
26.67	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
26.32	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
26.32	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
26.32	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
26.32	Single	5N2S	PSB36	5N2S-A₁-PSB36
26.32	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
26.32	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
26.32	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
26.32	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
26.32	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
26.32	Single	7C4S	S1P	7C4S-S1P₃-S1P
26.32	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
26.32	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
26.32	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
26.32	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
26.32	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
26.32	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
26.32	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
26.32	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
26.32	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
26.32	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
26.32	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
26.32	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
26.32	Single	8WGB	VU0155041	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
26.32	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
26.32	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
26.32	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
26.32	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
26.32	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
26.32	Single	9CIB	FCH-2296413	9CIB-HCA₂-FCH-2296413
26.32	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
26.32	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
26.32	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
26.32	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
26.32	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
26.32	Consensus	dp_off	Orthosteric Ligand	dp2_off
26.32	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
26.32	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
26.32	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
26.32	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
26.32	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
26.09	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
26.09	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
26.09	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
26.09	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
26.09	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
26.09	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
26.09	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
26.09	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
26.09	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
26.09	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
25.93	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
25.93	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
25.93	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
25.93	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
25.93	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
25.81	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
25.81	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
25.00	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
25.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
25.00	Single	5XR8	AM841	5XR8-CB₁-AM841
25.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
25.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
25.00	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
25.00	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
25.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
25.00	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
25.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
25.00	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
25.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
25.00	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
25.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
25.00	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
25.00	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
25.00	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
25.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
25.00	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
25.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
25.00	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
25.00	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
25.00	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
25.00	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
25.00	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
25.00	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
25.00	Single	8X0F	VU0424465	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
25.00	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
25.00	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
25.00	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
25.00	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
25.00	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
25.00	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
25.00	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
25.00	Single	9EGO	YVF	9EGO-CB₁-YVF-Gi1/β1/γ2
25.00	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
25.00	Single	9IK8	SST analogue	9IK8-SST1-SST analogue-Gi1/β1/γ2
25.00	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
25.00	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
25.00	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
25.00	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
25.00	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
25.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
25.00	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
25.00	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
25.00	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
25.00	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
25.00	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
24.14	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
24.14	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
24.14	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
24.00	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
24.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
24.00	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
24.00	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
24.00	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
24.00	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
23.81	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
23.81	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
23.81	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
23.81	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
23.81	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
23.81	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
23.81	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
23.81	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
23.81	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
23.81	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
23.81	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
23.81	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
23.81	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
23.81	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
23.81	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
23.81	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
23.53	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
23.53	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
23.53	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
23.53	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
23.53	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
23.53	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
23.53	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
23.53	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
23.53	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
23.53	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
23.53	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
23.53	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
23.53	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
23.53	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
23.53	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
23.53	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
23.53	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
23.53	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
23.53	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
23.53	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
23.53	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
23.53	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
23.53	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
23.53	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
23.33	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
23.33	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
23.33	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
23.33	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
23.33	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
23.33	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
23.08	Single	4A4M	All-trans-Retinal	4A4M-Rhodopsin-All-trans-Retinal-Gt(CT)
23.08	Single	5EN0	All-trans-Retinal	5EN0-Rhodopsin-All-trans-Retinal-Gt(CT)
23.08	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
23.08	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
23.08	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
23.08	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
23.08	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
23.08	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
23.08	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
23.08	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
23.08	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
23.08	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
23.08	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
22.73	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
22.73	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
22.73	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
22.73	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
22.73	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
22.73	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
22.73	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
22.73	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
22.73	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
22.73	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
22.73	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
22.58	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
22.58	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
22.22	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
22.22	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
22.22	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
22.22	Single	6TPK	Retosiban	6TPK-OT-Retosiban
22.22	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
22.22	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
22.22	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
22.22	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
22.22	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
22.22	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
22.22	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
22.22	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
22.22	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
22.22	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
22.22	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
22.22	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
22.22	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
22.22	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
22.22	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
22.22	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
22.22	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
22.22	Single	8Y6Y	GLPG0974	8Y6Y-FFA2-GLPG0974
22.22	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
22.22	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Gi1/β1/γ2
22.22	Single	9KPD	SA0	9KPD-TAS2R16-SA0-chim(Gs-CtGt3)/β1/γ2
22.22	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
22.22	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
22.22	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
22.22	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
22.22	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
22.22	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
22.22	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
22.22	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
21.74	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
21.74	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
21.74	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
21.74	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
21.74	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
21.74	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
21.43	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
21.43	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
21.43	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
21.43	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
21.43	Single	9KFK	Relaxin-3	9KFK-RXFP4-Relaxin-3-Gi2/β1/γ2
21.43	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
21.21	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
21.05	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
21.05	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
21.05	Single	6D27	CAY10471	6D27-DP₂-CAY10471
21.05	Single	6GPS	MK0812	6GPS-CCR2-MK0812
21.05	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
21.05	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
21.05	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
21.05	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
21.05	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
21.05	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
21.05	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
21.05	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
21.05	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
21.05	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
21.05	Single	9IZC	MK1903	9IZC-HCA₂-MK1903-Gi1/β1/γ2
21.05	Consensus	cck_off	Orthosteric Ligand	ccka_off
21.05	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
21.05	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
21.05	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
20.83	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.83	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.83	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
20.83	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
20.83	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.83	Single	8WKY	PG-934	8WKY-MC₄-PG-934
20.83	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Single	9HB3	Mambaquaretin-1	9HB3-V₂-Mambaquaretin-1
20.83	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
20.83	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
20.83	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
20.69	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
20.69	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
20.69	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
20.69	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
20.69	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
20.69	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
20.69	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
20.00	Single	2HPY	All-trans-Retinal	2HPY-Rhodopsin-All-trans-Retinal
20.00	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
20.00	Single	6GPX	MK0812	6GPX-CCR2-MK0812
20.00	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
20.00	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
20.00	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
20.00	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
20.00	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
20.00	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
20.00	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
20.00	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
20.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
20.00	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
20.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
20.00	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
20.00	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
20.00	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
20.00	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
20.00	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
20.00	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8Y02	Retinal	8Y02-OPN1SW-Retinal-Gi1/β1/γ2
20.00	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
20.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
20.00	Single	9E82	SDF-1-beta	9E82-ACKR3-SDF-1-β-Arrestin2
20.00	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
20.00	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
20.00	Single	9GE2	ML184	9GE2-GPR55-ML184-chim(NtGi1-G13)/β1/γ2
20.00	Single	9HC0	4YI	9HC0-mGlu₅-4YI
20.00	Single	9IQR	Muscarinic toxin 3	9IQR-α_2a-Muscarinic toxin 3
20.00	Single	9IQS	Muscarinic toxin 3	9IQS-M₄-Muscarinic toxin 3
20.00	Single	9IQV	Muscarinic toxin 3	9IQV-Alpha1A-Muscarinic toxin 3
20.00	Single	9KFI	Relaxin-3	9KFI-RXFP3-Relaxin-3-Gi2/β1/γ2
20.00	Single	9KPF	SA0	9KPF-TAS2R16-SA0-Gi1/β1/γ2
20.00	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
20.00	Consensus	blt_off	Orthosteric Ligand	blt1_off
20.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
20.00	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
20.00	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
20.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
20.00	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.00	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
20.00	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
20.00	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
20.00	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
20.00	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
20.00	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
19.35	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
19.35	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
19.35	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
19.35	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
19.35	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
19.23	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
19.23	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
19.23	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
19.23	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
19.23	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
19.23	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
19.23	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
19.23	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
19.23	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
19.23	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
19.23	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
19.23	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
19.23	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
19.23	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
19.23	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
19.23	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
19.05	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
19.05	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
19.05	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
19.05	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
19.05	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
19.05	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
19.05	Single	7P2L	4YI	7P2L-mGlu₅-4YI
19.05	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
19.05	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
19.05	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
19.05	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
19.05	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
19.05	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
19.05	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
19.05	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
19.05	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
19.05	Single	9UY3	Anamorelin	9UY3-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
19.05	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
19.05	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
19.05	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
19.05	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
19.05	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
19.05	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
19.05	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
18.75	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
18.75	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
18.75	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
18.75	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
18.75	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
18.75	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
18.75	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
18.75	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
18.75	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
18.52	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
18.52	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
18.52	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
18.52	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
18.52	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
18.52	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
18.52	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
18.52	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
18.52	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
18.52	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
18.52	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
18.52	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
18.18	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
18.18	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
18.18	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
18.18	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
18.18	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
18.18	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
18.18	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
18.18	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
18.18	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
18.18	Single	8XJN	Cloprosetnol	8XJN-TXA2-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
18.18	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
18.18	Single	9GGG	I-BOP	9GGG-TXA2-I-BOP-chim(NtGi2L-Gs-CtGq)/β1/γ2
18.18	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
18.18	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
18.18	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
17.86	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
17.86	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
17.86	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
17.86	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
17.86	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
17.86	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
17.86	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
17.86	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
17.86	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
17.86	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
17.65	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
17.65	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
17.65	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
17.65	Single	7XP6	Strychnine	7XP6-TAS2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
17.65	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
17.65	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
17.65	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
17.65	Single	9B9Y	7DY	9B9Y-CB₁-7DY
17.65	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
17.65	Single	9IZD	CHBA	9IZD-HCA₁-CHBA-Gi1/β1/γ2
17.39	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
17.39	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
17.39	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
17.39	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
17.39	Single	8XJO	U46619	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	9M1H	Prostaglandin E2	9M1H-EP₁-Prostaglandin E2-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
17.39	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
17.39	Consensus	tp_on	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
17.24	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
17.24	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
17.24	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
17.24	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
17.24	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
17.24	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
17.24	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
17.14	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
16.67	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
16.67	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
16.67	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
16.67	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
16.67	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
16.67	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
16.67	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
16.67	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
16.67	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
16.67	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
16.67	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
16.67	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
16.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
16.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
16.67	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
16.67	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
16.67	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
16.67	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
16.67	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
16.67	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
16.67	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
16.67	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
16.67	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
16.67	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
16.67	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
16.67	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
16.67	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
16.67	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
16.67	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
16.67	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
16.22	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
16.22	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
16.22	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
16.13	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
16.13	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
16.13	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
16.13	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
16.13	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
16.13	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
16.13	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
16.13	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
16.13	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
16.13	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
16.13	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
16.13	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
16.00	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
16.00	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
16.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
16.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
16.00	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
16.00	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
16.00	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
16.00	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
16.00	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
16.00	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
16.00	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
16.00	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
16.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
16.00	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
16.00	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
15.79	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
15.79	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
15.79	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
15.79	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
15.79	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
15.79	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
15.79	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
15.79	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
15.79	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
15.79	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
15.79	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070
15.79	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100
15.79	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
15.79	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
15.79	Single	9JMD	Azithromycin	9JMD-Motilin-Azithromycin-chim(Gs-CtGq)/β1/γ2
15.79	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
15.79	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
15.62	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
15.38	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
15.38	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
15.38	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
15.38	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
15.38	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
15.38	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
15.38	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
15.38	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
15.38	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
15.38	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
15.38	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
15.15	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
15.15	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
15.15	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
15.00	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
15.00	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
15.00	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
15.00	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
15.00	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
15.00	Single	6IIV	Daltroban	6IIV-TXA2-Daltroban
15.00	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
15.00	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
15.00	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
15.00	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
15.00	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
15.00	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
15.00	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
15.00	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
15.00	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
15.00	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
15.00	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
14.81	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
14.81	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.81	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
14.81	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
14.81	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
14.81	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
14.81	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
14.71	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
14.71	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
14.71	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
14.71	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
14.63	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
14.29	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
14.29	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
14.29	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
14.29	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
14.29	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
14.29	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.29	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
14.29	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
14.29	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
14.29	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
14.29	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
14.29	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
14.29	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
14.29	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
14.29	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
14.29	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
14.29	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
14.29	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
14.29	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
14.29	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
14.29	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
14.29	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
14.29	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
14.29	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
14.29	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
14.29	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
14.29	Consensus	ep_off	Orthosteric Ligand	ep4_off
14.29	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
14.29	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
14.29	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
14.29	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
14.29	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
13.89	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
13.89	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
13.79	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
13.79	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
13.79	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
13.79	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
13.79	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
13.79	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
13.79	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
13.79	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
13.79	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
13.79	Consensus	pac_on	Orthosteric Ligand	pac1_on
13.79	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
13.64	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
13.64	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
13.64	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
13.64	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
13.64	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
13.64	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
13.64	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
13.64	Single	9CLW	TUG-1375	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.64	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
13.64	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
13.33	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
13.33	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
13.33	Single	6FJ3	PTH	6FJ3-PTH1-PTH
13.33	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
13.33	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
13.33	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
13.33	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
13.33	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
13.33	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
13.33	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
13.33	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
13.33	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
13.33	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
13.33	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
13.33	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
13.33	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
13.33	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
13.33	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
13.33	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
13.33	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
13.04	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
13.04	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
13.04	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
13.04	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
13.04	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
13.04	Single	6IIU	Ramatroban	6IIU-TXA2-Ramatroban
13.04	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
13.04	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
13.04	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
13.04	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
13.04	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
13.04	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
13.04	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
13.04	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
13.04	Single	8Y6W	TUG-1375	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
13.04	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
13.04	Single	9CM3	TUG-1375	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.04	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
12.90	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
12.90	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
12.90	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
12.90	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
12.90	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
12.90	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
12.90	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
12.90	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
12.90	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
12.90	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
12.82	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
12.50	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
12.50	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.50	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
12.50	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
12.50	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
12.50	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
12.50	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
12.50	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
12.50	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
12.50	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
12.50	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
12.50	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
12.50	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
12.50	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
12.50	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
12.50	Single	9GG5	U46619	9GG5-TXA2-U46619-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.50	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
12.12	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
12.00	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
12.00	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
12.00	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
12.00	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
12.00	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
12.00	Single	9CM7	TUG-1375	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
12.00	Single	9NS9	TUG-1375	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
12.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
12.00	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
11.76	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
11.76	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
11.76	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
11.76	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
11.76	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
11.76	Single	9JHJ	C18:0 Ceramide	9JHJ-FPR2-ALX-C18:0 Ceramide-Gi1/β1/γ2
11.76	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
11.54	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
11.54	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
11.54	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
11.54	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
11.54	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
11.54	Single	9J0I	UDP-Glucuronic acid	9J0I-P2Y₁₄-UDP-Glucuronic acid-Gi1/β1/γ2
11.54	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
11.43	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
11.43	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
11.43	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
11.43	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
11.11	Single	6LI0	C17	6LI0-GPR52-C17
11.11	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
11.11	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
11.11	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
11.11	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
11.11	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
11.11	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
11.11	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
11.11	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
11.11	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
11.11	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
11.11	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
11.11	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
11.11	Single	9J0F	NADH	9J0F-P2Y₁₄-NADH-Gi1/β1/γ2
11.11	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
11.11	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
10.81	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
10.71	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.71	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.71	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
10.71	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
10.71	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.71	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.53	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
10.53	Single	5U09	Taranabant	5U09-CB₁-Taranabant
10.53	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
10.53	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
10.53	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
10.53	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.53	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
10.53	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
10.53	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
10.53	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
10.53	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
10.53	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
10.34	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
10.34	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
10.00	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
10.00	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
10.00	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
10.00	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
10.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
10.00	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
10.00	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
10.00	Single	9IXX	LTD4	9IXX-CysLT₂-LTD4-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
10.00	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
10.00	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
10.00	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
10.00	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
10.00	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
10.00	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
9.68	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
9.68	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
9.68	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
9.68	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
9.68	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
9.68	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.52	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
9.52	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
9.52	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.52	Single	8ZYY	Neurotensin peptide 8-13	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
9.38	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
9.38	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
9.38	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
9.09	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
9.09	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
9.09	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
9.09	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
9.09	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
9.09	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
9.09	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
9.09	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
9.09	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
9.09	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
9.09	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
9.09	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
9.09	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.09	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
9.09	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
9.09	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
8.82	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
8.82	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
8.82	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
8.70	Single	5TZR	MK8666	5TZR-FFA1-MK8666
8.70	Single	5V56	TC114	5V56-SMO-TC114
8.70	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
8.70	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
8.70	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
8.70	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
8.70	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
8.70	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
8.70	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.70	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.57	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
8.57	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
8.57	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
8.33	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
8.33	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
8.33	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
8.33	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
8.33	Single	6OS2	TRV026	6OS2-AT₁-TRV026
8.33	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
8.33	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
8.33	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.33	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
8.33	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.33	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
8.11	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
8.00	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
8.00	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
8.00	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
8.00	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
8.00	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
8.00	Single	9JH5	C16:0 Ceramide	9JH5-CysLT₂-C16:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
7.69	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
7.69	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
7.69	Single	8XQJ	JN241	8XQJ-Apelin-JN241
7.69	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
7.69	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
7.69	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
7.69	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
7.41	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
7.41	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
7.41	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
7.41	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
7.41	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
7.41	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
7.14	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
7.14	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
7.14	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
6.90	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
6.90	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
6.90	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
6.90	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
6.90	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
6.67	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
6.67	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/β1/γ2
6.45	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
6.25	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
6.25	Single	7V68	LY2119620	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
6.25	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
6.25	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
6.25	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
6.06	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
6.06	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
5.88	Single	7VDM	Substance-P	7VDM-MRGPRX2-Substance-P-Gi1/β1/γ2
5.88	Single	7Y14	Beta-Alanine	7Y14-MRGPRD-β-Alanine
5.88	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
5.56	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
5.56	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
5.56	Single	7Y12	Beta-Alanine	7Y12-MRGPRD-β-Alanine-Gi1/β1/γ2
5.56	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
5.26	Single	7S8N	R-Zinc-3573	7S8N-MRGPRX2-R-Zinc-3573-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.26	Single	7S8O	R-Zinc-3573	7S8O-MRGPRX2-R-Zinc-3573-Gi1/β1/γ2
5.26	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
5.26	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
5.26	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
5.26	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/β1/γ2
5.26	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
5.26	Single	8YKD	Dehydroepiandrosterone	8YKD-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
5.26	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
5.26	Single	9LMP	NE52-QQ57	9LMP-GPR4-NE52-QQ57
5.26	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg4_on
5.26	Consensus	adgrg_on_gp	Orthosteric Ligand	adgrg2_on_gp adgrg4_on_gp
5.26	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
5.26	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
5.00	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
5.00	Single	4XNV	BPTU	4XNV-P2Y₁-BPTU
5.00	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
5.00	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
5.00	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/β1/γ2
5.00	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
5.00	Single	7WV9	ZCZ011	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
5.00	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
5.00	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
5.00	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
5.00	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
4.76	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
4.76	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
4.76	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
4.76	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
4.76	Single	7T94	LY2119620	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
4.76	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
4.76	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/β1/γ2
4.76	Single	8IYX	YL-365	8IYX-GPR34-YL-365
4.76	Single	8JD6	VU0364770	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
4.76	Single	9JFU	NE52-QQ57	9JFU-GPR4-NE52-QQ57
4.76	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
4.55	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
4.55	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
4.55	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
4.55	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
4.55	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
4.55	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.55	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.35	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
4.35	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.35	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.35	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/β1/γ2
4.35	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
4.35	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
4.35	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
4.17	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
4.17	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
4.17	Single	5V57	TC114	5V57-SMO-TC114
4.17	Single	6OS1	TRV026	6OS1-AT₁-TRV026
4.17	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
4.17	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
4.17	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
4.17	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.17	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
4.17	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
4.17	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.00	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
4.00	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
4.00	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
4.00	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
4.00	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
4.00	Single	8XQJ	JN241	8XQJ-Apelin-JN241
4.00	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
4.00	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
4.00	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
4.00	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
4.00	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
3.85	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
3.85	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
3.85	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
3.85	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
3.85	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
3.85	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116
3.85	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.85	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.70	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
3.70	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
3.70	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
3.70	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
3.57	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2
3.57	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
3.57	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8

Consensus Members
	Id	Members
	alpha_on_gp	alpha1_on_gp alpha2_on_gp
	beta_on_gp	beta1_on_gp beta2_on_gp beta3_on_gp

Net Summary
I_min	2.70222
Number of Linked Nodes	917
Number of Links	1083
Number of Hubs	172
Number of Links mediated by Hubs	654
Number of Communities	25
Number of Nodes involved in Communities	203
Number of Links involved in Communities	287

Path Summary
Number Of Nodes in MetaPath	127
Number Of Links MetaPath	126
Number of Shortest Paths	3941051
Length Of Smallest Path	3
Average Path Length	45.9059
Length of Longest Path	78
Minimum Path Strength	0.372917
Average Path Strength	5.69032
Maximum Path Strength	20.9476
Minimum Path Correlation	0.700694
Average Path Correlation	0.97916
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.42857
Average % Of Corr. Nodes	28.4891
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	46.7322
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following differences:
	Id	1^st Network	2^nd Network
	adrenergic_off_on_gp	adrenergic_on_gp	adrenergic_off

This network is also present in following consensuses:
	Id	Components
	amine_on_gp	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download adrenergic_on_gp.zip

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