psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.30	G.HN.32	5.43	No	No	0	7	5
2	G.HN.30	G.HN.33	5.56111	No	No	0	7	4
3	G.HN.37	b.b5x2	4.10556	No	Yes	0	3	7
4	G.HN.39	G.HN.43	3.9	No	No	0	5	9
5	G.HN.39	b.b5x5	5.26778	No	Yes	0	5	5
6	G.HN.40	b.b5x2	7.45	No	Yes	0	7	7
7	G.HN.40	b.b5x3	4.59	No	Yes	0	7	9
8	G.HN.42	G.HN.45	3.16889	No	No	0	4	4
9	G.HN.43	b.b5x3	6.94667	No	Yes	0	9	9
10	G.HN.44	b.b5x3	7.52889	No	Yes	0	6	9
11	G.HN.47	b.b4x2	3.91667	No	No	0	6	8
12	G.HN.48	G.HN.52	4.13444	No	No	0	3	4
13	G.HN.50	b.b4x2	8.45222	No	No	0	5	8
14	G.S1.01	G.S2.05	4.24	Yes	Yes	2	6	6
15	G.S1.01	G.S3.02	3.00778	Yes	No	2	6	4
16	G.S1.01	G.S3.04	10.5	Yes	Yes	2	6	7
17	G.S1.02	G.S3.01	3.80778	Yes	Yes	3	5	3
18	G.S1.02	G.S3.03	6.40778	Yes	Yes	3	5	4
19	G.S1.02	G.h2s4.05	6.17333	Yes	No	0	5	9
20	G.H5.11	G.S1.02	4.09556	No	Yes	3	6	5
21	G.S1.03	G.S3.06	7.30556	No	Yes	0	9	7
22	G.S1.04	G.S3.03	5.27667	No	Yes	0	7	4
23	G.S1.04	G.S4.03	5.07556	No	No	0	7	8
24	G.S1.05	G.S1.07	5.69	No	No	0	9	9
25	G.S1.05	G.h2s4.01	11.3667	No	Yes	0	9	7
26	G.S1.05	G.S4.02	3.64444	No	No	0	9	8
27	G.H1.01	G.S1.06	5.32667	Yes	No	3	9	8
28	G.S1.06	G.S3.05	6.28111	No	Yes	3	8	6
29	G.S1.06	G.S3.07	5.43	No	Yes	3	8	5
30	G.H3.12	G.S1.07	5.07444	No	No	0	7	9
31	G.H1.01	G.s1h1.01	4.64889	Yes	No	0	9	9
32	G.H1.01	G.s1h1.05	3.06	Yes	No	0	9	9
33	G.H1.01	G.S3.07	5.22333	Yes	Yes	3	9	5
34	G.H1.01	G.S4.05	2.87333	Yes	No	0	9	9
35	G.H1.04	G.H1.08	3.40333	Yes	Yes	3	9	9
36	G.H1.04	G.S4.05	4.54667	Yes	No	0	9	9
37	G.H1.04	G.S5.05	3.49	Yes	Yes	3	9	9
38	G.H1.04	G.S5.07	5.35	Yes	No	3	9	8
39	G.H1.04	G.s6h5.01	3.04	Yes	Yes	3	9	4
40	G.H1.05	G.H1.09	3.03444	No	No	0	7	8
41	G.H1.07	G.H5.03	8.65556	No	Yes	0	9	4
42	G.H1.08	G.S2.06	5.25111	Yes	Yes	3	9	3
43	G.H1.08	G.S3.05	3.36889	Yes	Yes	3	9	6
44	G.H1.08	G.H5.04	3.04111	Yes	No	0	9	8
45	G.H1.09	G.h1ha.01	3.45	No	No	0	8	8
46	G.H1.10	G.s6h5.05	6.53111	No	No	0	7	8
47	G.H1.12	G.S2.06	3.77111	No	Yes	0	7	3
48	G.hfs2.07	b.l7x4	3.77111	No	Yes	0	7	9
49	G.S2.01	G.S3.08	3.41222	No	No	2	9	9
50	G.S2.01	b.l5x5	7.30889	No	Yes	2	9	9
51	G.S2.01	b.l7x2	5.07444	No	Yes	2	9	9
52	G.S2.03	G.S3.04	6.45	No	Yes	2	5	7
53	G.S2.03	G.S3.06	7.51333	No	Yes	2	5	7
54	G.S2.03	b.l5x5	2.90667	No	Yes	2	5	9
55	G.S2.04	G.S3.05	3.68	No	Yes	0	9	6
56	G.S2.05	G.S3.02	4.64333	Yes	No	2	6	4
57	G.S2.05	G.S3.04	12.0811	Yes	Yes	2	6	7
58	G.S2.06	G.S3.03	12.7411	Yes	Yes	3	3	4
59	G.S2.06	G.S3.05	2.9	Yes	Yes	3	3	6
60	G.S2.07	G.S3.02	9.27778	No	No	0	9	4
61	G.S2.08	G.s2s3.01	11.9967	Yes	No	3	3	5
62	G.H5.04	G.S2.08	10.1989	No	Yes	0	8	3
63	G.H5.05	G.S2.08	5.20556	No	Yes	3	7	3
64	G.H5.08	G.S2.08	6.19222	Yes	Yes	3	8	3
65	G.H5.05	G.s2s3.01	5.42222	No	No	3	7	5
66	G.H5.08	G.s2s3.01	7.03111	Yes	No	3	8	5
67	G.S3.01	G.S3.03	8.93111	Yes	Yes	3	3	4
68	G.H5.08	G.S3.01	5.54778	Yes	Yes	3	8	3
69	G.S3.01	I2x51	3.33111	Yes	No	0	3	6
70	G.S3.01	I2x54	3.31111	Yes	No	0	3	6
71	G.H5.11	G.S3.03	7.43111	No	Yes	3	6	4
72	G.S3.04	G.S3.06	4.82222	Yes	Yes	2	7	7
73	G.S3.06	G.h2s4.01	4.88333	Yes	Yes	2	7	7
74	G.S3.06	b.l5x5	14.59	Yes	Yes	2	7	9
75	G.H2.07	G.S3.08	8.04	Yes	No	2	9	9
76	G.S3.08	G.h2s4.01	3.49333	No	Yes	2	9	7
77	G.H2.02	G.s3h2.03	4.81333	Yes	Yes	2	9	9
78	G.H2.07	G.s3h2.03	6.45111	Yes	Yes	2	9	9
79	G.s3h2.03	b.l7x2	3.25111	Yes	Yes	2	9	9
80	G.s3h2.03	b.l7x4	3.52	Yes	Yes	0	9	9
81	G.s3h2.03	b.l9x6	5.13444	Yes	Yes	2	9	8
82	G.H2.02	G.H2.07	5.49111	Yes	Yes	2	9	9
83	G.H2.02	b.l9x6	5.51333	Yes	Yes	2	9	8
84	G.H2.02	b.l13x6	3.10889	Yes	Yes	2	9	9
85	G.H2.03	G.H2.05	10.05	No	No	0	8	9
86	G.H2.03	G.H2.06	3.6	No	Yes	0	8	8
87	G.H2.03	b.l13x6	3.61111	No	Yes	0	8	9
88	G.H2.04	G.H2.07	5.11111	No	Yes	0	9	9
89	G.H2.04	G.H3.08	4.04778	No	No	0	9	5
90	G.H2.04	G.H3.11	3.36778	No	No	0	9	5
91	G.H2.06	b.l9x6	3.31667	Yes	Yes	2	8	8
92	G.H2.06	b.b14x1	9.6	Yes	No	2	8	8
93	G.H2.06	b.l15x1	3.59111	Yes	No	2	8	7
94	G.H2.06	b.l17x6	8.60444	Yes	Yes	2	8	9
95	G.H2.06	b.b18x1	4.50778	Yes	No	2	8	9
96	G.H2.06	b.l19x1	3.07222	Yes	Yes	2	8	9
97	G.H2.07	G.h2s4.01	3.78667	Yes	Yes	2	9	7
98	G.H2.07	b.l7x2	4.55556	Yes	Yes	2	9	9
99	G.H2.07	b.l9x6	3.85889	Yes	Yes	2	9	8
100	G.H2.08	G.H3.18	5.02	No	Yes	0	9	5
101	G.H2.09	G.H2.10	3.44111	Yes	No	2	8	8
102	G.H2.09	G.H3.17	10.3444	Yes	Yes	2	8	4
103	G.H2.09	b.b2x1	6.89556	Yes	Yes	2	8	8
104	G.H2.09	b.l27x1	6.23	Yes	Yes	2	8	9
105	G.H2.10	b.b2x1	5.37778	No	Yes	2	8	8
106	G.H2.10	b.l3x1	3.56111	No	No	2	8	9
107	G.h2s4.01	b.l5x5	10.2433	Yes	Yes	2	7	9
108	G.H3.17	G.h2s4.02	7.26667	Yes	No	0	4	9
109	G.h2s4.02	b.l1x6	4.8	No	No	0	9	9
110	G.S4.01	G.S5.03	3.06889	No	No	0	7	6
111	G.H3.18	G.S4.02	8.09222	Yes	No	21	5	8
112	G.S4.02	G.h3s5.03	4.22222	No	No	21	8	4
113	G.H3.08	G.S4.04	5.27778	No	No	0	5	7
114	G.H3.09	G.S4.04	16.3144	Yes	No	0	9	7
115	G.S4.04	G.S5.04	3.24667	No	Yes	0	7	8
116	G.H3.05	G.S4.06	3.23222	No	No	0	9	7
117	G.H4.15	G.S4.06	8.30556	Yes	No	0	5	7
118	G.S4.07	G.s4h3.03	3.77444	No	No	0	7	9
119	G.S4.07	G.s5hg.01	3.21222	No	No	0	7	9
120	G.S5.06	G.s4h3.01	8.45778	No	No	0	9	8
121	G.HG.04	G.s4h3.01	7.71444	Yes	No	0	6	8
122	G.H4.11	G.s4h3.01	3.64556	No	No	0	6	8
123	G.s4h3.02	G.s5hg.01	6.46	No	No	0	7	9
124	G.HG.03	G.s4h3.02	6.67333	No	No	0	9	7
125	G.HG.07	G.s4h3.02	3.74	No	No	0	5	7
126	G.H3.01	G.s4h3.03	11.2489	Yes	No	0	9	9
127	G.H3.02	G.s4h3.03	3.07889	No	No	0	9	9
128	G.s4h3.04	G.s4h3.05	4.47111	Yes	Yes	6	8	8
129	G.H3.02	G.s4h3.04	3.85556	No	Yes	0	9	8
130	G.HG.04	G.s4h3.04	5.27333	Yes	Yes	6	6	8
131	G.HG.07	G.s4h3.04	4.91	No	Yes	6	5	8
132	G.HG.08	G.s4h3.04	3.76222	No	Yes	6	9	8
133	G.HG.15	G.s4h3.04	4.68889	No	Yes	0	5	8
134	G.hgh4.01	G.s4h3.04	5.37889	No	Yes	0	3	8
135	G.HG.07	G.s4h3.05	4.30444	No	Yes	6	5	8
136	G.HG.13	G.s4h3.05	3.76333	No	Yes	0	1	8
137	G.HG.17	G.s4h3.05	3.57778	No	Yes	0	4	8
138	G.H3.01	G.s4h3.06	5.66667	Yes	No	0	9	9
139	G.H3.01	G.s4h3.08	3.10222	Yes	No	0	9	5
140	G.s4h3.11	G.s4h3.14	4.15778	No	No	0	9	4
141	G.H3.03	G.s4h3.15	6.23556	No	No	0	8	6
142	G.H3.02	G.H4.15	3.18	No	Yes	0	9	5
143	G.H3.06	G.hgh4.02	5.32	No	Yes	0	9	6
144	G.H3.06	G.H4.15	7.18778	No	Yes	0	9	5
145	G.H3.06	G.h4s6.01	3.29778	No	No	0	9	4
146	G.H3.09	G.H3.13	3.10333	Yes	Yes	9	9	8
147	G.H3.09	G.S5.02	4.18444	Yes	No	9	9	7
148	G.H3.09	G.H4.15	3.81	Yes	Yes	0	9	5
149	G.H3.09	G.h4s6.01	5.81889	Yes	No	0	9	4
150	G.H3.09	G.S6.01	3.62778	Yes	No	0	9	4
151	G.H3.10	G.H3.14	6.73222	No	Yes	9	9	5
152	G.H3.10	G.h4s6.01	4.97667	No	No	0	9	4
153	G.H3.10	G.h4s6.03	3.38	No	No	9	9	8
154	G.H3.12	G.H3.18	3.48667	No	Yes	0	7	5
155	G.H3.13	G.H3.14	3.32333	Yes	Yes	9	8	5
156	G.H3.13	G.S5.02	3.08889	Yes	No	9	8	7
157	G.H3.13	G.h4s6.02	3.32	Yes	Yes	9	8	4
158	G.H3.13	G.h4s6.11	6.11	Yes	Yes	9	8	3
159	G.H3.14	G.h4s6.03	9.32333	Yes	No	9	5	8
160	G.H3.14	G.h4s6.04	2.94667	Yes	No	0	5	5
161	G.H3.15	G.H3.17	3.89222	No	Yes	0	8	4
162	G.H3.15	G.H3.18	5.10111	No	Yes	0	8	5
163	G.H3.16	G.H3.17	14.0511	No	Yes	0	8	4
164	G.H3.17	b.l25x6	5	Yes	No	2	4	8
165	G.H3.17	b.l27x1	3.43667	Yes	Yes	2	4	9
166	G.H3.18	G.h3s5.03	7.06222	Yes	No	21	5	4
167	G.h3s5.01	G.h3s5.02	4.33667	No	No	0	9	3
168	G.h3s5.01	G.h4s6.04	6.89889	No	No	0	9	5
169	G.h3s5.02	G.h4s6.10	4.49778	No	No	0	3	3
170	G.S5.01	G.S6.02	3.95778	No	Yes	23	7	5
171	G.H5.14	G.S5.01	3.59	No	No	23	8	7
172	G.S5.02	G.h4s6.11	2.90889	No	Yes	9	7	3
173	G.S5.03	G.S5.05	3.48778	No	Yes	0	6	9
174	G.H5.10	G.S5.03	3.25	No	No	0	4	6
175	G.S5.04	G.S5.06	3.22889	Yes	No	0	8	9
176	G.H4.15	G.S5.04	3.65222	Yes	Yes	0	5	8
177	G.S5.04	G.S6.03	7.20556	Yes	No	0	8	7
178	G.S5.05	G.S6.04	5.91111	Yes	No	3	9	5
179	G.S5.05	G.s6h5.01	5.19	Yes	Yes	3	9	4
180	G.H5.03	G.S5.05	4.56111	Yes	Yes	3	4	9
181	G.S5.06	G.S6.05	8.12111	No	Yes	0	9	9
182	G.S5.07	G.s6h5.01	9.58667	No	Yes	3	8	4
183	G.HG.01	G.HG.02	4.30333	No	No	0	9	5
184	G.H4.03	G.HG.01	7.29667	Yes	No	0	5	9
185	G.HG.04	G.HG.08	8.65111	Yes	No	6	6	9
186	G.H4.03	G.HG.04	2.97778	Yes	Yes	6	5	6
187	G.H4.03	G.HG.05	9.85111	Yes	No	0	5	9
188	G.HG.06	G.HG.12	3.3	No	No	0	5	2
189	G.HG.13	G.HG.14	4.54889	No	No	0	1	7
190	G.HG.14	G.HG.16	3.11111	No	No	0	7	7
191	G.HG.15	G.hgh4.05	7.29444	No	Yes	0	5	6
192	G.hgh4.01	G.hgh4.02	8.81	No	Yes	0	3	6
193	G.H4.10	G.hgh4.02	6.84111	Yes	Yes	22	3	6
194	G.H4.11	G.hgh4.02	3.22667	No	Yes	0	6	6
195	G.H4.14	G.hgh4.02	8.01667	No	Yes	22	3	6
196	G.hgh4.05	G.hgh4.07	4.66778	Yes	No	0	6	3
197	G.H4.05	G.hgh4.05	5.48556	No	Yes	0	4	6
198	G.H4.10	G.hgh4.05	20.1889	Yes	Yes	0	3	6
199	G.H4.02	G.hgh4.08	3.55333	No	No	24	3	7
200	G.H4.05	G.hgh4.08	5.43111	No	No	24	4	7
201	G.H4.03	G.H4.04	4.73889	Yes	No	0	5	4
202	G.H4.03	G.H4.07	3.26	Yes	No	6	5	7
203	G.H4.03	G.S6.05	3.32444	Yes	Yes	6	5	9
204	G.H4.07	G.S6.05	3.23333	No	Yes	6	7	9
205	G.H4.10	G.H4.14	13.4022	Yes	No	22	3	3
206	G.H4.12	G.H4.16	5.52111	No	No	6	7	8
207	G.H4.12	G.S6.03	15.4344	No	No	6	7	7
208	G.H4.12	G.S6.05	3.38222	No	Yes	6	7	9
209	G.H4.16	G.S6.01	6.22667	No	No	0	8	4
210	G.H4.16	G.S6.03	5.01556	No	No	6	8	7
211	6x18	G.H4.17	3.74	No	No	0	3	3
212	G.h4s6.02	G.h4s6.08	6.99444	Yes	No	0	4	4
213	G.h4s6.02	G.h4s6.11	5.28333	Yes	Yes	9	4	3
214	G.S6.01	G.h4s6.02	7.23778	No	Yes	0	4	4
215	G.h4s6.04	G.h4s6.11	3.16444	No	Yes	0	5	3
216	G.h4s6.09	G.h4s6.10	6.42556	No	No	0	3	3
217	G.S6.02	G.h4s6.12	9.72556	Yes	No	0	5	7
218	G.H5.17	G.h4s6.12	5.55	No	No	0	6	7
219	G.H5.10	G.S6.02	5.33667	No	Yes	0	4	5
220	G.H5.13	G.S6.02	6.51444	No	Yes	0	6	5
221	G.H5.14	G.S6.02	3.64778	No	Yes	23	8	5
222	G.H5.03	G.S6.04	4.82	Yes	No	3	4	5
223	G.H5.06	G.S6.04	20.7411	No	No	0	5	5
224	G.H5.03	G.s6h5.01	6.17333	Yes	Yes	3	4	4
225	G.s6h5.02	G.s6h5.04	3.19222	No	No	0	9	9
226	G.H5.02	G.s6h5.04	6.50889	No	No	0	9	9
227	G.H5.05	G.H5.09	9.28222	No	No	0	7	8
228	G.H5.08	G.H5.12	7.06	Yes	No	0	8	8
229	G.H5.12	I2x50	4.47111	No	No	0	8	8
230	G.H5.13	G.H5.17	11.37	No	No	0	6	6
231	5x68	G.H5.13	8.60333	No	No	0	7	6
232	G.H5.14	G.H5.18	3.28556	No	No	0	8	5
233	G.H5.15	I2x50	3.76556	No	No	0	7	8
234	G.H5.16	I2x50	9.40778	No	No	0	7	8
235	5x68	G.H5.16	9.60444	No	No	0	7	7
236	G.H5.17	G.H5.26	10.7533	No	Yes	0	6	7
237	3x53	G.H5.19	3.12667	No	No	0	8	4
238	G.H5.19	I2x53	21.1922	No	No	0	4	8
239	G.H5.20	G.H5.25	3.07556	Yes	Yes	0	8	8
240	G.H5.20	G.H5.26	4.19444	Yes	Yes	0	8	7
241	3x54	G.H5.20	9.35667	No	Yes	0	9	8
242	G.H5.21	G.H5.26	6.75444	No	Yes	0	9	7
243	G.H5.23	G.H5.25	3.52556	No	Yes	0	4	8
244	3x50	G.H5.23	7.73778	Yes	No	0	9	4
245	6x33	G.H5.25	7.37	No	Yes	0	8	8
246	6x36	G.H5.25	2.94889	No	Yes	0	8	8
247	6x37	G.H5.25	3.38333	Yes	Yes	0	8	8
248	5x69	G.H5.26	4.18667	No	Yes	25	6	7
249	6x29	G.H5.26	19.2422	No	Yes	25	7	7
250	b.1x3	b.1x7	6.23	No	No	0	1	8
251	b.1x4	b.1x7	4.12333	Yes	No	0	8	8
252	b.1x4	g.h1x5	3.50778	Yes	No	0	8	6
253	b.1x11	g.h1x11	3.07556	No	Yes	0	8	9
254	b.1x12	g.h1x11	4.07333	No	Yes	0	6	9
255	b.1x13	b.1x16	7.63444	No	No	0	1	4
256	b.1x15	b.1x19	4.59111	No	No	0	7	6
257	b.1x19	b.b21x1	7.01333	No	Yes	0	6	7
258	b.1x19	b.b21x2	4.15333	No	No	0	6	6
259	b.b21x2	b.lh12x1	4.04444	No	No	0	6	3
260	b.lh12x2	b.lh12x3	2.91778	Yes	No	0	8	4
261	b.lh12x2	g.l1x6	10.6	Yes	No	0	8	4
262	b.lh12x2	g.h2x2	6.37778	Yes	No	0	8	9
263	b.h2x3	b.lh12x4	6.45778	No	No	0	1	3
264	b.b21x4	b.h2x1	3.69111	No	No	0	5	5
265	b.b21x5	b.h2x1	5.49667	Yes	No	0	4	5
266	b.b21x5	b.h2x2	3.40667	Yes	No	0	4	1
267	b.h2x4	g.h2x5	2.88556	No	No	0	3	6
268	b.h2x5	b.l24x2	5.07667	No	No	0	5	6
269	b.h2x5	g.h2x9	3.51333	No	No	0	5	4
270	b.l22x5	b.lhb1x3	2.92444	Yes	No	0	9	2
271	b.lhb1x3	g.h2x9	5.34556	No	No	0	2	4
272	b.b24x7	b.lhb1x6	7.62556	No	No	0	9	3
273	b.lhb1x6	g.ctx6	4.47	No	Yes	0	3	6
274	b.b1x1	b.lhb1x10	4.02444	No	No	0	5	4
275	b.b25x7	b.lhb1x11	6.12444	No	Yes	10	7	4
276	b.b28x6	b.lhb1x11	3.10111	Yes	Yes	10	9	4
277	b.lhb1x11	g.ctx5	4.24111	Yes	No	0	4	9
278	b.b1x1	b.b1x3	4.14667	No	Yes	0	5	7
279	b.b1x2	b.b28x4	8.34222	No	Yes	10	3	6
280	b.b1x2	b.b28x6	7.54778	No	Yes	10	3	9
281	b.b1x3	b.b28x7	7.5	Yes	Yes	11	7	9
282	b.b1x3	g.ctx16	3.68333	Yes	Yes	11	7	8
283	b.b1x4	b.b5x1	4.88444	No	No	0	7	5
284	b.b1x4	b.b28x5	3.61889	No	No	11	7	5
285	b.b1x4	g.ctx16	3.20889	No	Yes	11	7	8
286	b.b1x5	b.l1x1	7.90333	No	No	0	3	7
287	b.b1x5	b.b28x4	6.17222	No	Yes	0	3	6
288	b.b1x6	b.b4x6	17.4611	Yes	Yes	0	9	9
289	b.b1x6	b.b5x1	3.60222	Yes	No	0	9	5
290	b.b1x6	b.b28x3	4.92333	Yes	Yes	0	9	7
291	b.b1x6	b.b28x5	3.48778	Yes	No	0	9	5
292	b.b28x2	b.l1x1	4.75222	Yes	No	0	4	7
293	b.b5x3	b.l1x2	2.90778	Yes	No	0	9	9
294	b.l1x3	b.l1x7	9.28111	Yes	No	8	9	9
295	b.b3x4	b.l1x3	7.12778	No	Yes	8	9	9
296	b.b3x6	b.l1x3	12.2411	No	Yes	8	9	9
297	b.l1x3	b.l3x2	4.76	Yes	Yes	8	9	9
298	b.b4x4	b.l1x3	11.0489	No	Yes	8	8	9
299	b.b4x6	b.l1x3	5.05444	Yes	Yes	8	9	9
300	b.l1x5	b.l3x2	3.43111	No	Yes	0	7	9
301	b.b2x1	b.l1x6	6.76778	Yes	No	2	8	9
302	b.l1x6	b.l27x1	22.5644	No	Yes	2	9	9
303	b.b3x6	b.l1x7	4.30111	No	No	8	9	9
304	b.b28x3	b.l1x7	3.32778	Yes	No	0	7	9
305	b.b2x1	b.l3x1	11.7744	Yes	No	2	8	9
306	b.b2x1	b.l27x1	9.21667	Yes	Yes	2	8	9
307	b.b2x2	b.b6x3	3.21	No	No	0	7	8
308	b.b2x3	b.b2x5	4.91333	No	Yes	0	6	7
309	b.b26x2	b.b2x3	5.4	No	No	0	7	6
310	b.b2x4	b.b6x5	3.27	No	Yes	0	6	6
311	b.b10x4	b.b2x4	14.5433	No	No	0	6	6
312	b.b2x5	b.b3x2	8.60556	Yes	No	0	7	5
313	b.b2x5	b.l4x1	5.49111	Yes	No	0	7	5
314	b.b2x5	b.l26x1	11.5922	Yes	No	0	7	7
315	b.b27x2	b.b2x5	4.32333	No	Yes	0	5	7
316	b.b6x5	b.l2x1	4.51	Yes	No	0	6	5
317	b.l2x3	b.l2x5	3.70444	No	No	0	8	5
318	b.b3x1	b.l2x3	5.88111	No	No	0	5	8
319	b.l26x1	b.l2x4	6.75	No	No	27	7	5
320	b.l26x3	b.l2x4	8.83556	No	No	27	7	5
321	b.b4x7	b.l2x5	13.6311	No	No	0	8	5
322	b.l2x5	b.l4x2	23.55	No	Yes	0	5	4
323	b.b3x1	b.b4x7	3.91889	No	No	0	5	8
324	b.b3x2	b.b4x6	5.82	No	Yes	0	5	9
325	b.b3x3	b.b4x3	3.80778	Yes	Yes	0	8	7
326	b.b3x3	b.b4x5	3.41222	Yes	Yes	0	8	7
327	b.b3x3	b.b6x3	3.22778	Yes	No	0	8	8
328	b.b3x3	b.b6x5	3.08556	Yes	Yes	0	8	6
329	b.b3x3	b.b7x2	3.20667	Yes	No	0	8	8
330	b.b3x4	b.b4x6	6.86333	No	Yes	8	9	9
331	b.b28x3	b.b3x4	4.50333	Yes	No	0	7	9
332	b.b3x5	b.l5x6	3.20444	No	No	0	9	9
333	b.b3x5	b.b6x3	3.41	No	No	0	9	8
334	b.b3x6	b.l3x2	7.03444	No	Yes	8	9	9
335	b.l3x1	b.l5x5	4.99111	No	Yes	2	9	9
336	b.b4x2	b.l3x2	6.91444	No	Yes	0	8	9
337	b.b4x1	b.l5x1	3.99	No	Yes	0	8	8
338	b.b4x3	b.b5x7	5.86889	Yes	Yes	0	7	7
339	b.b4x3	b.l5x1	4.15333	Yes	Yes	16	7	8
340	b.b4x3	b.b7x4	4.40778	Yes	No	16	7	8
341	b.b4x4	b.b4x6	16.7044	No	Yes	8	8	9
342	b.b4x4	b.b5x3	5.81556	No	Yes	8	8	9
343	b.b4x5	b.b5x4	3.24222	Yes	No	20	7	5
344	b.b4x5	b.b5x5	6.48111	Yes	Yes	20	7	5
345	b.b4x5	b.l8x1	4.43889	Yes	No	0	7	5
346	b.b4x6	b.b5x3	9.53778	Yes	Yes	8	9	9
347	b.b4x7	b.l4x3	6.42444	No	No	0	8	6
348	b.l4x1	g.ctx16	4.84222	No	Yes	0	5	8
349	b.l4x2	g.ctx15	8.80889	Yes	Yes	11	4	9
350	b.l4x2	g.ctx16	6.87556	Yes	Yes	11	4	8
351	b.b5x2	b.l4x3	9.58556	Yes	No	0	7	6
352	b.b5x4	b.b5x5	6.15111	No	Yes	20	5	5
353	b.b5x5	b.l8x8	4.30444	Yes	No	0	5	4
354	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
355	b.b5x7	b.b8x4	6.98333	Yes	Yes	0	7	6
356	b.b5x7	b.l8x8	9.89889	Yes	No	0	7	4
357	b.l5x1	b.l5x6	4.13889	Yes	No	0	8	9
358	b.b7x4	b.l5x1	4.40778	No	Yes	16	8	8
359	b.b8x4	b.l5x1	5.6	Yes	Yes	16	6	8
360	b.l5x2	b.l8x10	4.64889	No	No	0	6	4
361	b.b9x3	b.l5x2	6.46	Yes	No	0	6	6
362	b.l5x3	b.l7x3	10.3067	No	No	0	8	9
363	b.l5x4	b.l5x5	5.07889	No	Yes	0	8	9
364	b.l5x5	b.l7x2	8.09667	Yes	Yes	2	9	9
365	b.b6x1	b.l7x1	3.10444	No	No	0	9	9
366	b.b6x1	b.l9x6	4.12333	No	Yes	0	9	8
367	b.b10x2	b.b6x2	3.19222	No	No	0	6	8
368	b.b10x3	b.b6x2	3.94333	No	No	0	8	8
369	b.b6x5	b.l6x4	5.63222	Yes	No	0	6	5
370	b.b6x5	b.l8x1	2.86556	Yes	No	0	6	5
371	b.b10x5	b.l6x1	7.55111	Yes	No	0	9	6
372	b.b10x5	b.l6x2	3.04667	Yes	No	0	9	6
373	b.l6x3	b.l6x5	7.94667	No	Yes	17	6	4
374	b.l10x3	b.l6x3	8.99667	No	No	17	6	6
375	b.b7x1	b.l6x5	3.87778	Yes	Yes	17	4	4
376	b.l6x5	b.l8x2	7.61667	Yes	No	0	4	4
377	b.l10x3	b.l6x5	3.44111	No	Yes	17	6	4
378	b.b7x1	b.b8x3	3.09222	Yes	No	0	4	6
379	b.b7x1	b.b8x5	11.7589	Yes	No	0	4	4
380	b.b7x1	b.b9x1	2.96778	Yes	No	0	4	4
381	b.b7x1	b.l10x3	6.51667	Yes	No	17	4	6
382	b.b7x2	b.l8x1	5.62889	No	No	0	8	5
383	b.b10x5	b.b7x3	4.00556	Yes	No	0	9	9
384	b.b7x4	b.b8x4	4.18222	No	Yes	16	8	6
385	b.l7x3	b.l7x5	3.88889	No	Yes	0	9	6
386	b.l7x4	b.l9x5	3.95778	Yes	No	0	9	8
387	b.b9x3	b.l7x5	4.85889	Yes	Yes	0	6	6
388	b.b8x1	b.l9x7	3.17222	No	Yes	0	8	7
389	b.b10x3	b.b8x1	4.24667	No	No	0	8	8
390	b.b8x2	b.b8x4	5.79556	No	Yes	0	8	6
391	b.b8x2	b.b9x3	5.75	No	Yes	0	8	6
392	b.b10x5	b.b8x3	4.04778	Yes	No	0	9	6
393	b.b8x3	b.l12x1	5.56111	No	No	0	6	6
394	b.b8x4	b.l8x10	5.74889	Yes	No	0	6	4
395	b.b8x5	b.l8x3	3.08667	No	Yes	0	4	3
396	b.l8x3	b.l8x9	3.30556	Yes	No	0	3	3
397	b.l8x5	b.l8x7	5.69556	No	No	0	3	3
398	b.l8x5	b.l8x9	3.23	No	No	0	3	3
399	b.b12x6	b.b9x4	16.0711	Yes	No	0	8	9
400	b.l9x3	b.l9x7	3.43	Yes	Yes	12	9	7
401	b.b11x4	b.l9x3	6.08778	Yes	Yes	12	9	9
402	b.b11x6	b.l9x3	15.8089	No	Yes	12	9	9
403	b.l11x2	b.l9x3	5.88	Yes	Yes	12	9	9
404	b.b12x6	b.l9x3	8.22667	Yes	Yes	12	8	9
405	b.l11x2	b.l9x4	8.51222	Yes	No	0	9	5
406	b.l11x1	b.l9x6	7.08222	No	Yes	2	9	8
407	b.l13x6	b.l9x6	7.79222	Yes	Yes	2	9	8
408	b.b14x1	b.l9x6	5.45333	No	Yes	2	8	8
409	b.b11x4	b.l9x7	4.75	Yes	Yes	12	9	7
410	b.b10x1	b.b11x5	3.26	No	No	0	9	6
411	b.b10x1	b.b14x1	2.89444	No	No	0	9	8
412	b.b10x2	b.b10x4	3.86889	No	No	0	6	6
413	b.b10x2	b.b14x3	3.17222	No	Yes	0	6	5
414	b.b10x3	b.b11x4	3.94333	No	Yes	0	8	9
415	b.b10x5	b.b11x2	6.83889	Yes	No	0	9	7
416	b.b11x1	b.l10x1	5.02556	No	No	0	5	3
417	b.b14x5	b.l10x1	5.07444	No	No	0	5	3
418	b.b11x1	b.l10x2	3.48222	No	No	0	5	5
419	b.b12x7	b.l10x4	5.23667	No	No	0	9	3
420	b.l10x4	b.l12x2	6.13444	No	No	0	3	6
421	b.b11x1	b.b12x5	4.14	No	No	0	5	6
422	b.b11x2	b.b12x6	2.86778	No	Yes	0	7	8
423	b.b11x2	b.l12x1	4.74556	No	No	0	7	6
424	b.b11x3	b.b14x3	5.29778	No	Yes	5	5	5
425	b.b11x3	b.b14x5	3.31111	No	No	0	5	5
426	b.b11x3	b.b15x1	4.66	No	Yes	5	5	9
427	b.b11x4	b.b12x6	9.97222	Yes	Yes	12	9	8
428	b.b11x5	b.l13x7	5.56556	No	Yes	0	6	9
429	b.b11x5	b.b14x3	5.00667	No	Yes	0	6	5
430	b.b11x6	b.l11x2	6.70556	No	Yes	12	9	9
431	b.l11x1	b.l13x6	4.47222	No	Yes	2	9	9
432	b.b12x2	b.l11x2	7.54889	No	Yes	0	7	9
433	b.b12x2	b.l13x1	3.66333	No	No	0	7	2
434	b.b12x3	b.b13x7	3.87889	Yes	Yes	5	8	7
435	b.b12x3	b.l13x7	4.17333	Yes	Yes	5	8	9
436	b.b12x3	b.b15x1	2.94889	Yes	Yes	5	8	9
437	b.b12x3	b.b15x3	3.05778	Yes	Yes	5	8	9
438	b.b12x4	b.b13x3	5.05111	No	No	12	4	4
439	b.b12x5	b.b13x4	2.94667	No	No	5	6	4
440	b.b12x5	b.b13x5	4.25889	No	No	5	6	4
441	b.b12x6	b.b13x3	14.6033	Yes	No	12	8	4
442	b.b12x7	b.l12x3	8.67222	No	No	0	9	5
443	b.b13x2	b.l12x3	3.14778	No	No	0	4	5
444	b.b13x3	b.b13x6	6.14	No	No	0	4	4
445	b.b13x4	b.b13x5	3.66333	No	No	5	4	4
446	b.b13x5	b.b13x7	5.04444	No	Yes	5	4	7
447	b.b13x7	b.b15x1	10.7167	Yes	Yes	5	7	9
448	b.b13x7	b.b16x6	15.1422	Yes	Yes	5	7	8
449	b.b13x7	b.b17x1	4.01667	Yes	No	0	7	4
450	b.l13x3	b.l13x7	6.15111	Yes	Yes	5	9	9
451	b.b15x3	b.l13x3	5.11222	Yes	Yes	5	9	9
452	b.b15x5	b.l13x3	8.13	No	Yes	5	8	9
453	b.l13x3	b.l15x2	5.18	Yes	Yes	0	9	9
454	b.b16x4	b.l13x3	14.9922	Yes	Yes	5	6	9
455	b.b16x6	b.l13x3	3.99667	Yes	Yes	5	8	9
456	b.l13x4	b.l15x2	7.22778	No	Yes	0	3	9
457	b.l13x6	b.l15x1	3.63111	Yes	No	2	9	7
458	b.b15x3	b.l13x7	3.23111	Yes	Yes	5	9	9
459	b.b15x5	b.l13x7	3.01556	No	Yes	5	8	9
460	b.b14x2	b.b18x3	6.19111	No	Yes	0	7	8
461	b.b14x3	b.b15x1	6.22556	Yes	Yes	5	5	9
462	b.b14x4	b.b18x5	6.16444	No	No	0	8	5
463	b.b18x5	b.l14x1	5.24	No	No	0	5	4
464	b.l14x2	b.l18x4	3.60889	No	No	0	4	7
465	b.l14x3	b.l14x5	7.14667	No	No	0	5	5
466	b.l14x5	b.l16x2	7.93667	No	No	0	5	9
467	b.b16x5	b.l14x6	6.30556	Yes	No	0	5	3
468	b.b16x7	b.l14x6	3.01667	Yes	No	0	9	3
469	b.b15x1	b.b16x6	11.5811	Yes	Yes	5	9	8
470	b.b15x2	b.b16x5	3.64222	Yes	Yes	0	6	5
471	b.b15x2	b.b18x3	5.80222	Yes	Yes	4	6	8
472	b.b15x2	b.b18x5	10.6344	Yes	No	0	6	5
473	b.b15x2	b.b19x2	9.46778	Yes	Yes	4	6	6
474	b.b15x3	b.b16x6	5.90222	Yes	Yes	5	9	8
475	b.b15x4	b.l17x7	3.72556	No	No	0	6	7
476	b.l15x1	b.l17x6	8.47111	No	Yes	2	7	9
477	b.b16x2	b.l15x2	7.68889	No	Yes	0	5	9
478	b.b16x4	b.b16x6	7.99111	Yes	Yes	5	6	8
479	b.b16x4	b.b17x3	6.46556	Yes	No	5	6	5
480	b.b16x4	b.b17x6	10.8444	Yes	No	0	6	7
481	b.b16x5	b.b17x4	2.96889	Yes	Yes	0	5	5
482	b.b16x5	b.b17x5	3.54667	Yes	Yes	0	5	7
483	b.b16x5	b.l20x1	7.07333	Yes	No	0	5	6
484	b.b16x6	b.b17x3	5.94889	Yes	No	5	8	5
485	b.b16x7	b.l16x2	3.96889	Yes	No	0	9	9
486	b.b16x7	b.l16x3	10.2489	Yes	No	18	9	3
487	b.b16x7	b.b17x4	10.8522	Yes	Yes	18	9	5
488	b.l16x1	b.l16x2	3.48667	No	No	0	4	9
489	b.b17x2	b.l16x3	6.61556	No	No	18	3	3
490	b.b17x4	b.l16x3	3.49	Yes	No	18	5	3
491	b.b17x2	b.b17x4	3.58222	No	Yes	18	3	5
492	b.b17x3	g.h1x10	4.06778	No	No	0	5	9
493	b.b17x5	b.b17x7	8.98	Yes	Yes	4	7	8
494	b.b17x5	b.b21x1	13.6322	Yes	Yes	4	7	7
495	b.b17x5	g.l1x2	3.96556	Yes	No	4	7	2
496	b.b17x6	g.h1x14	6.90111	No	No	0	7	9
497	b.b17x7	b.b19x2	10.0022	Yes	Yes	4	8	6
498	b.b17x7	b.b20x6	10.2411	Yes	Yes	4	8	6
499	b.b17x7	b.b21x1	5.30889	Yes	Yes	4	8	7
500	b.l17x3	b.l17x7	9.42778	Yes	No	4	9	7
501	b.b19x4	b.l17x3	8.21222	Yes	Yes	4	8	9
502	b.b19x6	b.l17x3	13.6378	No	Yes	0	9	9
503	b.b20x4	b.l17x3	18.3044	Yes	Yes	4	8	9
504	b.b20x6	b.l17x3	2.89	Yes	Yes	4	6	9
505	b.l17x4	b.l19x2	10.6822	No	Yes	0	3	9
506	b.l17x5	b.l17x6	3.92556	No	Yes	2	6	9
507	b.l17x5	b.l19x1	3.76111	No	Yes	2	6	9
508	b.l17x5	b.l19x2	3.59778	No	Yes	0	6	9
509	b.l17x6	b.l19x1	6.80222	Yes	Yes	2	9	9
510	b.b19x4	b.l17x7	4.39111	Yes	No	4	8	7
511	b.b18x1	b.l19x1	12.1156	No	Yes	2	9	9
512	b.b18x2	b.b22x3	3.39111	No	No	0	5	6
513	b.b18x3	b.b19x2	4.32444	Yes	Yes	4	8	6
514	b.b18x3	b.b19x4	4.22222	Yes	Yes	4	8	8
515	b.l18x1	b.l18x2	9.95	Yes	Yes	13	6	7
516	b.b22x5	b.l18x1	7.50111	Yes	Yes	13	7	6
517	b.l18x1	b.l22x4	4.18222	Yes	No	13	6	9
518	b.l18x1	g.h2x8	5.95444	Yes	No	0	6	7
519	b.l18x1	g.h2x11	4.58444	Yes	Yes	13	6	6
520	b.b22x5	b.l18x2	4.81444	Yes	Yes	13	7	7
521	b.l18x2	b.l22x4	3.83444	Yes	No	13	7	9
522	b.l18x2	g.h2x11	4.63333	Yes	Yes	13	7	6
523	b.l18x3	b.l18x5	8.32667	No	No	0	5	2
524	b.l18x3	g.h2x11	15.6344	No	Yes	0	5	6
525	b.l18x5	b.l20x2	9.50778	No	No	0	2	9
526	b.b19x2	b.b20x6	9.40889	Yes	Yes	4	6	6
527	b.b19x3	b.b22x5	2.92444	No	Yes	0	4	7
528	b.b19x4	b.b20x6	5.47556	Yes	Yes	4	8	6
529	b.b19x5	b.l21x9	4.11444	No	No	0	5	6
530	b.b19x6	b.l19x2	3.92556	No	Yes	0	9	9
531	b.b20x2	b.l19x2	5.62222	No	Yes	0	6	9
532	b.b20x2	b.b20x4	6.46778	No	Yes	0	6	8
533	b.b20x2	b.l21x1	3.91111	No	No	0	6	2
534	b.b20x3	b.b21x7	4.03111	No	Yes	0	8	5
535	b.b20x3	b.l21x9	4.72889	No	No	0	8	6
536	b.b20x4	b.b20x6	4.86889	Yes	Yes	4	8	6
537	b.b20x4	b.b21x3	14.7311	Yes	No	4	8	6
538	b.b20x4	b.b21x6	6.18	Yes	No	4	8	1
539	b.b20x5	b.b21x4	4.61444	No	No	0	7	5
540	b.b20x5	b.b21x7	5.85889	No	Yes	0	7	5
541	b.b20x6	b.b21x3	6.34778	Yes	No	4	6	6
542	b.b20x7	b.l20x3	4.45889	No	No	0	9	7
543	b.b20x7	b.b21x4	7.39111	No	No	0	9	5
544	b.b20x7	g.h2x4	3.60222	No	No	0	9	7
545	b.l20x2	g.l1x5	8.07222	No	No	0	9	4
546	b.l20x2	g.h2x7	7.01556	No	No	0	9	5
547	b.b21x1	g.l1x2	3.73333	Yes	No	4	7	2
548	b.b21x1	g.l1x4	7.27889	Yes	Yes	4	7	8
549	b.b21x3	b.b21x6	4.70222	No	No	4	6	1
550	b.b21x5	b.b21x7	10.1122	Yes	Yes	0	4	5
551	b.b21x5	b.b25x1	3.39889	Yes	No	0	4	2
552	b.b21x7	b.b23x2	3.77778	Yes	No	0	5	6
553	b.b21x7	b.b24x6	7.07222	Yes	Yes	0	5	8
554	b.l21x2	b.l21x4	7.22889	No	No	0	4	4
555	b.b25x3	b.l21x2	7.39667	Yes	No	0	5	4
556	b.b23x6	b.l21x5	7.11889	Yes	No	0	7	4
557	b.l21x7	b.l23x1	5.53111	No	Yes	0	5	6
558	b.l21x7	b.l23x2	6.56778	No	No	0	5	8
559	b.l21x8	b.l23x1	2.97889	No	Yes	0	4	6
560	b.b23x6	b.l21x9	10.0744	Yes	No	0	7	6
561	b.b22x1	b.l23x1	4.17667	No	Yes	0	8	6
562	b.b22x2	b.b26x3	5.34	No	No	0	8	6
563	b.b22x4	b.b26x3	3.5	No	No	0	5	6
564	b.b22x4	b.b26x4	3.09333	No	No	0	5	5
565	b.b22x4	b.b26x5	3.05444	No	No	0	5	7
566	b.b22x5	b.b23x2	9.06667	Yes	No	0	7	6
567	b.b23x1	b.l22x1	4.83889	No	No	0	5	9
568	b.l22x1	g.ctx3	7.68667	No	Yes	0	9	9
569	b.l22x1	g.ctx5	4.33889	No	No	0	9	9
570	b.l22x3	g.ctx3	10.31	No	Yes	0	9	9
571	b.b24x7	b.l22x5	11.3789	No	Yes	0	9	9
572	b.l22x5	b.l24x2	6.07333	Yes	No	26	9	6
573	b.l22x5	g.h2x12	2.94	Yes	No	26	9	7
574	b.l22x5	g.ctx6	3.37444	Yes	Yes	0	9	6
575	b.b23x1	b.b24x5	4.80111	No	No	0	5	5
576	b.b23x3	b.b24x5	3.80778	No	No	0	7	5
577	b.b23x3	b.b27x1	3.80778	No	No	0	7	6
578	b.b23x4	b.b23x6	4.59667	No	Yes	0	6	7
579	b.b23x5	b.l25x7	3.68	No	No	0	7	7
580	b.b23x6	b.l23x2	3.70556	Yes	No	0	7	8
581	b.b23x6	b.b24x4	8.78667	Yes	Yes	14	7	6
582	b.b23x6	b.b24x6	6.75222	Yes	Yes	14	7	8
583	b.l23x1	b.l25x6	18.7933	Yes	No	0	6	8
584	b.b24x2	b.l23x2	6.43444	No	No	0	5	8
585	b.b24x1	b.b24x2	3.35778	No	No	0	4	5
586	b.b24x2	b.l25x1	2.95222	No	No	0	5	3
587	b.b24x3	b.b25x7	5.11222	No	No	0	5	7
588	b.b24x4	b.b24x6	6.15222	Yes	Yes	14	6	8
589	b.b24x4	b.b25x3	11.1156	Yes	Yes	14	6	5
590	b.b24x4	b.b25x6	3.44889	Yes	No	14	6	3
591	b.b24x6	b.b25x3	4.55556	Yes	Yes	14	8	5
592	b.b24x7	b.l24x3	8.29556	No	Yes	0	9	5
593	b.l24x2	g.h2x12	5.29222	No	No	26	6	7
594	b.b25x2	b.l24x3	5.68444	No	Yes	0	2	5
595	b.b25x3	b.b25x6	3.63333	Yes	No	14	5	3
596	b.b25x7	b.b28x6	16.9567	No	Yes	10	7	9
597	b.l25x3	b.l25x7	3.53556	Yes	No	0	9	7
598	b.b27x3	b.l25x3	6.99778	No	Yes	0	8	9
599	b.b27x5	b.l25x3	14.4122	No	Yes	10	9	9
600	b.l25x3	b.l27x2	6.02	Yes	Yes	10	9	9
601	b.b28x4	b.l25x3	9.60667	Yes	Yes	10	6	9
602	b.l25x4	b.l27x2	7.24222	No	Yes	0	5	9
603	8x56	b.l25x4	6.76	No	No	0	6	5
604	b.l25x5	b.l27x1	7.28222	No	Yes	0	7	9
605	b.l25x6	b.l27x1	20.7678	No	Yes	2	8	9
606	b.b26x1	b.b26x2	3.63111	No	No	0	9	7
607	b.b26x1	b.l27x1	4.94111	No	Yes	0	9	9
608	b.b26x3	b.b27x3	3.93222	No	No	0	6	8
609	b.b26x5	b.b27x1	3.56444	No	No	0	7	6
610	b.l26x1	b.l26x3	5.30111	No	No	27	7	7
611	b.l26x3	b.l26x5	7.24	No	No	0	7	5
612	b.l26x5	g.ctx4	5.03111	No	No	0	5	7
613	b.l26x5	g.ctx15	4.65889	No	Yes	0	5	9
614	b.b28x7	b.l26x6	3.12667	Yes	No	11	9	7
615	b.l26x6	g.ctx16	5.08333	No	Yes	11	7	8
616	b.b27x3	b.b28x6	7.41222	No	Yes	0	8	9
617	b.b27x5	b.l27x2	8.01667	No	Yes	10	9	9
618	b.b28x2	b.l27x2	10.7467	Yes	Yes	0	4	9
619	b.b28x1	b.b28x2	4.55	No	Yes	0	4	4
620	I1x48	b.b28x2	8.67111	No	Yes	0	7	4
621	b.b28x4	b.b28x6	6.70222	Yes	Yes	10	6	9
622	b.b28x5	g.ctx16	5.72222	No	Yes	11	5	8
623	b.b28x7	g.ctx14	9.98889	Yes	Yes	0	9	9
624	b.b28x7	g.ctx16	4.16111	Yes	Yes	11	9	8
625	g.h1x1	g.h1x5	3.93222	No	No	0	2	6
626	g.h1x10	g.h1x14	5.94556	No	No	0	9	9
627	g.l1x2	g.l1x4	4.87111	No	Yes	4	2	8
628	g.h2x3	g.l1x5	3.71556	No	No	0	5	4
629	g.h2x3	g.h2x7	5.37667	No	No	0	5	5
630	g.h2x11	g.h2x15	12.9444	Yes	No	0	6	6
631	g.ctx3	g.ctx4	3.39889	Yes	No	0	9	7
632	g.ctx3	g.ctx6	6.33444	Yes	Yes	0	9	6
633	g.ctx10	g.ctx9	3.92333	No	No	28	5	6
634	g.ctx13	g.ctx9	5.06889	No	No	28	5	6
635	g.ctx14	g.ctx9	6.07444	Yes	No	0	9	6
636	g.ctx10	g.ctx13	11.3556	No	No	28	5	5
637	g.ctx12	g.ctx13	5.26889	No	No	0	6	5
638	g.ctx14	g.ctx15	5.25222	Yes	Yes	0	9	9
639	g.ctx14	g.ctx17	4.15333	Yes	Yes	0	9	7
640	g.ctx15	g.ctx16	3.04778	Yes	Yes	11	9	8
641	2x63	Lig	7.29444	Yes	Yes	0	6	0
642	3x32	Lig	14.0289	Yes	Yes	1	8	0
643	3x33	Lig	7.48444	No	Yes	0	8	0
644	3x36	Lig	6.10889	No	Yes	1	7	0
645	3x37	Lig	4.15111	Yes	Yes	1	8	0
646	E2x52	Lig	4.94778	No	Yes	0	6	0
647	5x43	Lig	5.96333	No	Yes	0	8	0
648	5x461	Lig	3.04222	No	Yes	1	8	0
649	6x51	Lig	16.1133	Yes	Yes	1	8	0
650	6x52	Lig	8.54111	Yes	Yes	1	7	0
651	7x38	Lig	4.79333	No	Yes	1	7	0
652	7x42	Lig	8.40333	Yes	Yes	1	8	0
653	1x31	1x32	3.25667	No	No	0	4	4
654	1x39	2x61	4.73	No	No	0	7	7
655	1x39	7x39	12.0211	No	No	0	7	8
656	1x43	2x57	6.18333	No	Yes	0	7	8
657	1x44	1x48	4.19556	No	No	0	4	4
658	1x46	2x54	3.42	No	No	0	8	8
659	1x49	7x55	3.22222	No	Yes	0	9	6
660	1x50	2x50	7.62778	No	Yes	0	9	9
661	1x50	2x51	5.03555	No	No	0	9	8
662	1x50	7x50	6.69889	No	No	0	9	9
663	1x53	2x47	3.39	Yes	No	0	9	9
664	1x53	7x54	4.33444	Yes	No	7	9	8
665	1x53	7x55	4.49	Yes	Yes	0	9	6
666	1x53	8x50	2.91222	Yes	Yes	7	9	8
667	1x54	2x48	3.92111	No	No	0	7	7
668	1x56	8x54	4.77778	No	Yes	0	8	8
669	1x57	8x50	5.72	No	Yes	0	8	8
670	1x59	1x60	3.38778	No	Yes	7	6	7
671	1x59	8x57	5.70778	No	No	7	6	7
672	1x60	I1x50	4.27111	Yes	Yes	7	7	8
673	1x60	8x53	4.52667	Yes	No	7	7	8
674	1x60	8x56	6.9	Yes	No	0	7	6
675	1x60	8x57	3.03667	Yes	No	7	7	7
676	2x40	I1x50	5.34222	No	Yes	7	9	8
677	8x49	I1x50	3.16667	No	Yes	7	7	8
678	8x50	I1x50	6.63222	Yes	Yes	7	8	8
679	8x53	I1x50	2.97667	No	Yes	7	8	8
680	2x41	I1x51	8.39	No	No	0	6	8
681	2x37	2x40	10.4444	No	No	0	8	9
682	2x38	I2x57	13.2211	No	No	0	7	8
683	2x40	8x50	6.71333	No	Yes	7	9	8
684	2x41	4x39	4.63333	No	No	0	6	5
685	2x42	3x49	4.97667	No	No	0	8	9
686	2x42	4x45	4.15	No	No	0	8	6
687	2x45	3x42	5.57889	No	Yes	1	9	8
688	2x45	4x46	10.3233	No	No	1	9	8
689	2x46	2x50	5.73	Yes	Yes	1	9	9
690	2x46	3x42	6.99667	Yes	Yes	1	9	8
691	2x46	3x43	3.22889	Yes	Yes	1	9	8
692	2x46	7x49	8.54445	Yes	Yes	1	9	9
693	2x49	3x38	5.68667	No	No	1	9	8
694	2x49	3x42	8.97333	No	Yes	1	9	8
695	2x49	4x50	8.08667	No	Yes	1	9	9
696	2x50	3x39	5.23556	Yes	No	0	9	9
697	2x50	7x46	5.4	Yes	No	0	9	9
698	2x50	7x49	5.68556	Yes	Yes	1	9	9
699	2x52	4x50	4.26556	No	Yes	0	7	9
700	2x53	3x35	3.41889	No	No	0	8	7
701	2x53	7x46	4.12889	No	No	0	8	9
702	2x54	2x57	3.16667	No	Yes	0	8	8
703	2x551	3x31	3.69111	No	No	0	6	5
704	2x56	3x32	6.97667	No	Yes	1	8	8
705	2x56	7x42	3.22667	No	Yes	1	8	8
706	2x57	7x42	6.38333	Yes	Yes	0	8	8
707	2x59	3x28	7.88	No	No	0	6	6
708	2x60	7x42	4.15	No	Yes	0	7	8
709	2x62	2x66	4.61445	No	No	0	6	5
710	2x63	E1x50	8.03889	Yes	Yes	0	6	9
711	2x64	7x35	3.70778	No	No	0	7	6
712	2x64	7x39	7.18222	No	No	0	7	8
713	2x66	E1x51	3.27444	No	No	0	5	5
714	E1x49	E1x51	4.00333	No	No	0	5	5
715	E1x49	E2.D185	7.68222	No	No	0	5	4
716	E1x50	E1x52	10.7556	Yes	No	15	9	7
717	3x24	E1x50	3.36778	No	Yes	15	6	9
718	3x25	E1x50	6.53	No	Yes	15	9	9
719	3x28	E1x50	5.67778	No	Yes	0	6	9
720	E1x50	E2x50	10.3033	Yes	No	15	9	9
721	3x24	E1x52	7.53444	No	No	15	6	7
722	3x22	E2.R181	4.15333	No	Yes	19	4	4
723	3x25	E2x50	7.28	No	No	15	9	9
724	3x26	E2.R176	3.44111	Yes	Yes	19	7	6
725	3x26	E2.R181	4.36667	Yes	Yes	19	7	4
726	3x29	E2x52	4.58	No	No	0	7	6
727	3x32	3x36	2.94	Yes	No	1	8	7
728	3x32	7x42	10.3422	Yes	Yes	1	8	8
729	3x33	4x57	4.84778	No	No	0	8	8
730	3x34	4x50	5.69111	No	Yes	0	6	9
731	3x34	4x54	10.4211	No	No	0	6	5
732	3x34	4x57	4.17	No	No	0	6	8
733	3x36	6x48	4.06111	No	Yes	1	7	8
734	3x37	4x53	3.43778	Yes	No	0	8	8
735	3x37	4x56	5.57333	Yes	No	0	8	8
736	3x37	5x461	3.91444	Yes	No	1	8	8
737	3x38	3x42	5.42111	No	Yes	1	8	8
738	3x38	4x50	16.8833	No	Yes	1	8	9
739	3x40	5x50	3.20111	No	No	0	8	9
740	3x40	6x44	3.06889	No	Yes	1	8	9
741	3x40	6x48	11.8744	No	Yes	1	8	8
742	3x41	3x44	4.06444	No	No	0	7	7
743	3x41	4x52	13.3111	No	No	0	7	5
744	3x41	5x50	12.6111	No	No	0	7	9
745	3x42	4x46	4.27111	Yes	No	1	8	8
746	3x42	4x49	10.8	Yes	No	0	8	8
747	3x42	4x50	3.41	Yes	Yes	1	8	9
748	3x43	6x44	3.78778	Yes	Yes	1	8	9
749	3x43	7x49	7.93444	Yes	Yes	1	8	9
750	3x43	7x53	6.64111	Yes	Yes	1	8	9
751	3x45	4x45	3.32667	No	No	0	8	6
752	3x46	3x50	5.56778	No	Yes	1	9	9
753	3x46	7x53	5.50556	No	Yes	1	9	9
754	3x47	5x58	5.63444	No	Yes	0	9	9
755	3x48	3x52	15.0567	No	No	0	6	5
756	3x48	5x57	5.22889	No	No	0	6	7
757	3x49	I2x57	8.07333	No	No	0	9	8
758	3x50	5x58	5.71556	Yes	Yes	1	9	9
759	3x50	7x53	5.6	Yes	Yes	1	9	9
760	3x51	3x52	3.53667	Yes	No	0	9	5
761	3x51	3x55	13.0378	Yes	No	0	9	8
762	3x51	5x57	5.98889	Yes	No	0	9	7
763	3x51	5x60	11.0911	Yes	No	0	9	7
764	3x51	5x61	3.76444	Yes	No	0	9	9
765	3x52	4x41	6	No	No	0	5	7
766	3x56	I2x52	6.94667	No	No	0	7	6
767	I2x52	I2x56	6.29889	No	No	0	6	5
768	4x41	I2x52	8.47111	No	No	0	7	6
769	I2x53	I2x57	12.3489	No	No	0	8	8
770	4x38	4x39	3.5	No	No	0	8	5
771	4x51	4x55	3.38444	No	No	0	5	5
772	4x54	4x58	2.93111	No	No	0	5	6
773	4x56	5x42	4.83444	No	No	0	8	5
774	4x58	4x59	3.76556	No	No	0	6	8
775	4x59	4x60	5.84	No	No	0	8	7
776	4x60	5x39	14.0633	No	Yes	0	7	8
777	4x64	5x39	3.85889	No	Yes	0	6	8
778	E2.D180	E2.R176	8.07333	No	Yes	0	4	6
779	E2.R176	E2.R181	4.38333	Yes	Yes	19	6	4
780	E2.A186	E2.D183	2.91556	No	No	0	4	1
781	5x39	E2.S190	3.25111	Yes	No	0	8	6
782	5x37	6x60	14.9578	No	No	0	4	5
783	5x37	E3.E372	3.14333	No	No	0	4	3
784	5x39	5x43	8.19556	Yes	No	0	8	8
785	5x40	6x59	8.74222	No	No	0	7	7
786	5x41	5x45	5.16444	No	No	0	7	5
787	5x41	6x60	3.76556	No	No	0	7	5
788	5x44	5x48	3.19222	No	Yes	1	7	7
789	5x44	6x52	3.74667	No	Yes	1	7	7
790	5x44	6x56	5.73	No	No	1	7	7
791	5x45	5x48	6.53222	No	Yes	0	5	7
792	5x47	5x48	6.87667	Yes	Yes	1	8	7
793	5x47	5x51	6.90222	Yes	Yes	1	8	7
794	5x47	6x44	6.66889	Yes	Yes	1	8	9
795	5x47	6x48	3.56444	Yes	Yes	1	8	8
796	5x47	6x49	5.95444	Yes	Yes	0	8	7
797	5x47	6x52	19.4089	Yes	Yes	1	8	7
798	5x48	6x56	5.07889	Yes	No	1	7	7
799	5x49	5x50	3.39	No	No	0	6	9
800	5x51	5x55	3.99667	Yes	No	0	7	6
801	5x51	6x44	3.38222	Yes	Yes	1	7	9
802	5x51	6x45	3.01222	Yes	Yes	0	7	7
803	5x54	5x58	4.78778	No	Yes	1	9	9
804	5x54	6x41	4.81444	No	No	1	9	8
805	5x54	6x44	5.66778	No	Yes	1	9	9
806	5x55	6x41	3.61333	No	No	0	6	8
807	5x56	5x60	4.79444	No	No	0	5	7
808	5x58	6x37	4.16778	Yes	Yes	0	9	8
809	5x58	6x40	6.31222	Yes	No	0	9	8
810	5x58	6x41	3.05889	Yes	No	1	9	8
811	5x62	5x66	8.55111	Yes	No	0	6	7
812	5x62	6x37	4.05667	Yes	Yes	0	6	8
813	5x66	5x70	6.63222	No	No	29	7	6
814	5x66	6x30	8.52889	No	No	29	7	8
815	5x67	5x68	3.80222	No	No	0	6	7
816	5x67	5x71	3.85889	No	No	0	6	5
817	5x69	6x29	4.45333	No	No	25	6	7
818	5x70	6x30	7.88444	No	No	29	6	8
819	6x14	6x16	8.55	No	No	0	1	3
820	6x20	6x23	6.97889	No	No	0	4	4
821	6x25	6x29	10.2033	No	No	0	4	7
822	6x35	6x39	3.39333	No	No	0	7	7
823	6x43	7x52	5.23556	No	No	0	7	8
824	6x44	6x48	5.12222	Yes	Yes	1	9	8
825	6x45	6x49	4.59667	Yes	Yes	0	7	7
826	6x47	7x45	8.92333	No	No	0	8	9
827	6x48	6x52	6.01444	Yes	Yes	1	8	7
828	6x48	7x41	7.03444	Yes	No	0	8	8
829	6x48	7x45	11.5511	Yes	No	0	8	9
830	6x49	6x50	3.28	Yes	No	0	7	9
831	6x49	6x53	5.71111	Yes	No	0	7	7
832	6x51	6x52	8.81333	Yes	Yes	1	8	7
833	6x51	7x37	2.93111	Yes	No	0	8	6
834	6x51	7x38	5.37	Yes	No	1	8	7
835	6x54	6x58	3.64222	No	No	0	6	4
836	6x54	7x37	3.41444	No	No	0	6	6
837	6x58	E3.M377	5.33889	No	No	0	4	4
838	6x61	E3.C375	3.43778	No	No	0	5	4
839	7x30	E3.M377	3.91444	No	No	0	7	4
840	7x30	7x33	4.19667	No	No	0	7	6
841	7x32	7x36	3.48889	No	No	0	3	4
842	7x39	7x42	10.3967	No	Yes	0	8	8
843	7x45	7x49	10.2922	No	Yes	0	9	9
844	7x51	7x56	3.34778	No	No	0	6	8
845	7x52	7x53	4.83556	No	Yes	0	8	9
846	7x54	8x50	5.08333	No	Yes	7	8	8
847	7x55	8x54	8.93889	Yes	Yes	0	6	8
848	8x47	8x49	8.08	No	No	7	9	7
849	8x47	8x50	8.18778	No	Yes	7	9	8
850	8x48	8x51	6.93	No	No	0	6	9
851	8x49	8x50	3.45	No	Yes	7	7	8
852	8x50	8x54	3.92778	Yes	Yes	0	8	8
853	G.H4.02	G.H4.05	3.60556	No	No	24	3	4
854	g.ctx1	g.ctx2	4.8	No	No	0	1	3
855	b.b1x3	g.ctx17	4.85667	Yes	Yes	0	7	7
856	3x22	3x26	3.48	No	Yes	19	4	7
857	3x26	4x61	4.00444	Yes	No	0	7	6
858	7x33	7x37	3.96556	No	No	0	6	6
859	b.b12x4	b.b12x6	4.46889	No	Yes	12	4	8
860	2x64	Lig	3.16556	No	Yes	0	7	0
861	1x47	2x55	2.85111	No	No	0	7	6
862	G.S5.07	G.s1h1.06	2.82778	No	No	0	8	9
863	G.H3.04	G.s4h3.08	2.81889	No	No	0	4	5
864	2x55	2x551	2.81444	No	No	0	6	6
865	1x46	7x47	2.80111	No	No	0	8	7
866	5x36	5x38	2.79556	No	No	0	6	5
867	E2.R176	E2.S190	2.78222	Yes	No	0	6	6
868	b.1x18	g.l1x4	2.76667	No	Yes	0	4	8
869	b.lh12x2	g.h2x1	2.75778	Yes	No	0	8	8
870	b.lhb1x11	b.lhb1x9	2.75556	Yes	No	0	4	3
871	2x38	4x39	2.74778	No	No	0	7	5
872	b.b12x7	b.b13x4	2.73222	No	No	0	9	4
873	b.b25x4	b.lhb1x9	2.70778	No	No	0	4	3
874	G.hfs2.03	b.b9x3	2.69333	No	Yes	0	9	6
875	5x58	5x61	2.68889	Yes	No	0	9	9
876	E2.D183	E2.P184	2.68333	No	No	0	1	1
877	5x36	5x39	2.68333	No	Yes	0	6	8
878	G.s1h1.02	G.s1h1.05	2.66	No	No	0	7	9
879	3x44	5x53	2.64444	No	No	0	7	7
880	b.1x22	g.l1x4	2.63111	No	Yes	0	3	8
881	G.H1.03	G.s1h1.06	2.62889	No	No	0	9	9
882	I2x54	I2x55	2.62889	No	No	0	6	5
883	b.h2x1	g.h2x5	2.62778	No	No	0	5	6
884	G.H5.07	G.S5.05	2.62	No	Yes	0	3	9
885	G.H4.06	G.HG.04	2.61667	No	Yes	0	4	6
886	b.l22x2	g.ctx3	2.61333	No	Yes	0	1	9
887	b.l24x3	b.lhb1x5	2.60222	Yes	No	0	5	1
888	b.lhb1x10	b.lhb1x8	2.59667	No	No	0	4	2
889	G.H5.01	G.s6h5.05	2.57	No	No	0	9	8
890	6x20	6x24	2.55	No	No	0	4	5
891	2x42	4x46	2.53444	No	No	0	8	8
892	b.1x15	g.h1x15	2.52778	No	No	0	7	8
893	b.l22x2	b.l26x4	2.51778	No	No	0	1	9
894	1x36	2x65	2.51444	No	No	0	5	6
895	G.hfs2.04	G.hfs2.06	2.50222	No	No	0	6	9
896	1x47	2x51	2.48333	No	No	0	7	8
897	1x52	8x54	2.48	No	Yes	0	8	8
898	b.b7x5	b.l9x7	2.47	No	Yes	0	9	7
899	G.s4h3.07	G.s4h3.15	2.46556	No	No	0	8	6
900	b.b10x5	b.b6x4	2.46333	Yes	No	0	9	7
901	b.b16x3	b.b19x2	2.46222	No	Yes	0	6	6
902	6x43	7x48	2.45778	No	No	0	7	6
903	2x38	4x42	2.45333	No	No	0	7	7
904	b.1x4	g.h1x4	2.45222	Yes	No	0	8	5
905	G.hfs2.06	b.l7x4	2.43556	No	Yes	0	9	9
906	b.l13x1	b.l13x2	2.42667	No	No	0	2	6
907	2x43	7x53	2.42	No	Yes	0	8	9
908	b.l1x4	b.l3x2	2.41444	No	Yes	0	6	9
909	b.l26x2	b.l2x2	2.40889	No	No	0	1	1
910	4x58	4x62	2.37778	No	No	0	6	6
911	b.b9x2	b.l12x1	2.36889	No	No	0	5	6
912	G.H1.05	G.S3.05	2.36444	No	Yes	0	7	6
913	G.hfs2.05	b.l7x5	2.36444	No	Yes	0	7	6
914	G.HN.37	G.HN.41	2.36333	No	No	0	3	4
915	g.h1x12	g.h1x8	2.36	No	No	0	6	7
916	G.H3.01	G.s1h1.04	2.32667	Yes	No	0	9	9
917	b.b19x1	b.l18x1	2.31	No	Yes	0	6	6
918	5x40	6x60	2.30444	No	No	0	7	5
919	4x38	4x40	2.3	No	No	0	8	6
920	6x39	7x52	2.29	No	No	0	7	8
921	b.b27x4	b.b28x3	2.28	No	Yes	0	5	7
922	b.b24x5	b.b25x5	2.24889	No	No	0	5	4
923	b.b21x2	g.h2x1	2.22889	No	No	0	6	8
924	b.1x13	b.1x9	2.19	No	No	0	1	4
925	b.1x2	g.h1x1	2.17778	No	No	0	1	2
926	8x52	8x55	2.17778	No	No	0	6	6
927	b.l7x5	b.l9x1	2.16333	Yes	No	0	6	5
928	7x50	7x55	2.16222	No	Yes	0	9	6
929	6x19	6x23	2.15222	No	No	0	5	4
930	3x30	4x61	2.14667	No	No	0	7	6
931	b.h2x2	b.lh12x4	2.13333	No	No	0	1	3
932	b.b16x2	b.l17x1	2.13333	No	No	0	5	2
933	1x35	1x39	2.13	No	No	0	5	7
934	b.l10x1	b.l14x4	2.12778	No	No	0	3	1
935	G.S2.05	G.h1ha.03	2.12	Yes	No	0	6	3
936	1x35	2x65	2.11667	No	No	0	5	6
937	g.h1x10	g.h1x13	2.11556	No	No	0	9	1
938	g.h2x14	g.h2x15	2.11333	No	No	0	4	6
939	1x48	1x52	2.11333	No	No	0	4	8
940	7x51	7x55	2.10222	No	Yes	0	6	6
941	G.H1.11	G.H1.12	2.06333	No	No	0	8	7
942	6x59	E2.K191	2.04444	No	No	0	7	5
943	E2.E179	E2.T177	2.03667	No	No	0	3	5
944	b.b12x6	b.l9x2	2.03333	Yes	No	0	8	5
945	G.S1.03	G.h2s4.04	2.02667	No	No	0	9	5
946	b.b12x1	b.l13x5	2.02222	No	No	0	6	5
947	b.b18x4	b.b22x5	2.01778	No	Yes	0	3	7
948	b.b13x1	b.b9x2	2	No	No	0	4	5
949	G.H4.10	G.hgh4.04	1.99667	Yes	No	0	3	5
950	G.H3.04	G.s4h3.14	1.98222	No	No	0	4	4
951	G.H3.03	G.hgh4.01	1.96556	No	No	0	8	3
952	1x57	2x44	1.95667	No	No	0	8	6
953	G.S2.02	G.S3.07	1.94667	No	Yes	0	9	5
954	g.ctx7	g.ctx8	1.94444	No	No	0	4	8
955	1x45	7x47	1.94222	No	No	0	5	7
956	5x65	G.H5.20	1.92889	No	Yes	0	8	8
957	6x14	6x17	1.92444	No	No	0	1	3
958	2x63	E2.D185	1.91556	Yes	No	0	6	4
959	G.HN.45	G.HN.48	1.89556	No	No	0	4	3
960	5x62	6x34	1.89222	Yes	No	0	6	8
961	6x23	6x27	1.88889	No	No	0	4	5
962	b.l14x1	b.l14x2	1.87	No	No	0	4	4
963	b.l13x5	b.l15x2	1.86444	No	Yes	0	5	9
964	1x42	7x47	1.84333	No	No	0	7	7
965	I1x49	I1x50	1.83333	No	Yes	0	6	8
966	b.b22x3	b.b23x2	1.82111	No	No	0	6	6
967	b.l8x3	b.l8x6	1.82	Yes	No	0	3	4
968	G.HN.43	b.b5x6	1.80111	No	No	0	9	6
969	G.H1.10	G.H1.11	1.79889	No	No	0	7	8
970	G.HG.01	G.s6h5.02	1.79556	No	No	0	9	9
971	g.ctx2	g.h2x15	1.77778	No	No	0	3	6
972	G.s4h3.08	G.s4h3.10	1.76778	No	No	0	5	4
973	5x46	5x49	1.76111	No	No	0	5	6
974	E2.E179	E2.S182	1.75556	No	No	0	3	3
975	1x32	2x65	1.75111	No	No	0	4	6
976	E2.P178	E2.T177	1.75	No	No	0	5	5
977	7x34	E3.M377	1.74889	No	No	0	4	4
978	G.HN.36	b.b5x2	1.73667	No	Yes	0	4	7
979	3x21	E1x50	1.71889	No	Yes	0	7	9
980	6x18	G.h4s6.08	1.71111	No	No	0	3	4
981	G.HN.51	b.l1x4	1.71	No	No	0	5	6
982	1x54	2x47	1.7	No	No	0	7	9
983	g.h1x11	g.h1x7	1.69222	Yes	No	0	9	2
984	g.ctx11	g.ctx17	1.68889	No	Yes	0	4	7
985	G.S3.07	G.s3h2.01	1.68	Yes	No	0	5	9
986	b.l21x2	b.l21x3	1.68	No	No	0	4	3
987	b.b20x6	b.l17x2	1.67222	Yes	No	0	6	6
988	G.H1.02	G.H1.03	1.67111	No	No	0	9	9
989	1x42	7x43	1.66778	No	No	0	7	5
990	G.HG.06	G.HG.09	1.65	No	No	0	5	6
991	G.s2s3.02	I2x55	1.64778	No	No	0	4	5
992	2x57	2x58	1.64	Yes	No	0	8	9
993	b.b21x7	b.l24x1	1.62889	Yes	No	0	5	5
994	5x69	6x26	1.62111	No	No	0	6	5
995	3x54	5x64	1.62	No	No	0	9	6
996	b.lhb1x4	b.lhb1x5	1.61	No	No	0	1	1
997	G.hgh4.03	G.hgh4.04	1.57222	No	No	0	7	5
998	b.1x11	g.h1x12	1.56667	No	No	0	8	6
999	4x63	4x64	1.56556	No	No	0	5	6
1000	b.l2x2	b.l6x2	1.55556	No	No	0	1	6
1001	6x51	6x55	1.54	Yes	No	0	8	8
1002	b.1x17	b.1x20	1.53556	No	No	0	2	2
1003	G.H3.04	G.H3.07	1.52889	No	No	0	4	6
1004	G.s1h1.02	G.s1h1.03	1.51667	No	No	0	7	8
1005	b.l25x1	b.l25x2	1.51667	No	No	0	3	5
1006	b.1x14	g.h1x15	1.51556	No	No	0	4	8
1007	5x59	5x62	1.51	No	Yes	0	3	6
1008	g.h2x13	g.h2x14	1.51	No	No	0	1	4
1009	G.HG.05	G.HG.09	1.5	No	No	0	9	6
1010	G.HN.10	G.HN.11	1.47222	No	No	0	4	2
1011	g.ctx6	g.ctx7	1.47111	Yes	No	0	6	4
1012	G.H1.02	G.H1.06	1.45667	No	No	0	9	6
1013	E3.S373	E3.S374	1.44889	No	No	0	3	5
1014	b.lhb1x6	b.lhb1x7	1.43111	No	No	0	3	1
1015	4x55	5x42	1.43	No	No	0	5	5
1016	g.ctx17	g.ctx18	1.42222	Yes	No	0	7	6
1017	G.HN.11	G.HN.34	1.41	No	No	0	2	3
1018	G.HN.53	G.hns1.03	1.37667	No	No	0	1	4
1019	2x39	3x49	1.36889	No	No	0	8	9
1020	6x32	G.H5.24	1.35444	No	No	0	8	4
1021	G.hns1.03	I2x55	1.34	No	No	0	4	5
1022	2x63	E2.A186	1.33111	Yes	No	0	6	4
1023	b.1x10	b.1x11	1.33	No	No	0	1	8
1024	6x57	6x61	1.33	No	No	0	6	5
1025	1x33	1x37	1.32444	No	No	0	5	4
1026	1x32	2x67	1.32	No	No	0	4	5
1027	1x41	1x45	1.31444	No	No	0	4	5
1028	b.b16x1	b.l17x3	1.29778	No	Yes	0	4	9
1029	g.h1x3	g.ntx8	1.28222	No	No	0	3	4
1030	6x22	6x25	1.28	No	No	0	6	4
1031	G.H4.01	G.HG.14	1.26778	No	No	0	3	7
1032	7x36	7x40	1.26778	No	No	0	4	8
1033	b.b20x1	b.l21x5	1.26111	No	No	0	5	4
1034	6x32	G.H5.26	1.24	No	Yes	0	8	7
1035	1x51	2x51	1.22889	No	No	0	5	8
1036	6x15	G.H4.13	1.22444	No	No	0	5	5
1037	g.h1x13	g.h1x9	1.20333	No	No	0	1	6
1038	6x53	6x57	1.19778	No	No	0	7	6
1039	5x60	5x63	1.18667	No	No	0	7	5
1040	6x27	6x30	1.17889	No	No	0	5	8
1041	1x40	1x43	1.17556	No	No	0	4	7
1042	b.1x10	b.1x13	1.17444	No	No	0	1	1
1043	b.1x4	g.h1x8	1.15889	Yes	No	0	8	7
1044	6x61	E3.S374	1.14778	No	No	0	5	5
1045	7x40	7x41	1.14	No	No	0	8	8
1046	5x36	E2.T177	1.12444	No	No	0	6	5
1047	1x34	1x38	1.11	No	No	0	3	5
1048	4x48	4x52	1.11	No	No	0	3	5
1049	3x27	3x31	1.07556	No	No	0	5	5
1050	g.h1x2	g.h1x5	1.03111	No	No	0	2	6
1051	g.h1x3	g.h1x4	1.01222	No	No	0	3	5
1052	G.HN.31	G.HN.32	1.00667	No	No	0	1	5
1053	G.S1.01	G.hns1.01	1.00667	Yes	No	0	6	3
1054	E2.R181	E2x51	1.00667	Yes	No	0	4	5
1055	5x52	5x56	0.993333	No	No	0	5	5
1056	6x42	6x45	0.977778	No	Yes	0	6	7
1057	b.1x15	g.h1x11	0.953333	No	Yes	0	7	9
1058	6x45	6x46	0.95	Yes	No	0	7	5
1059	G.HN.42	G.HN.46	0.935556	No	No	0	4	4
1060	b.1x21	g.l1x4	0.928889	No	Yes	0	3	8
1061	b.l4x2	g.ctx19	0.927778	Yes	No	0	4	8
1062	1x37	1x38	0.922222	No	No	0	4	5
1063	G.h2s4.02	G.h2s4.03	0.911111	No	No	0	9	7
1064	G.HN.38	G.HN.41	0.9	No	No	0	3	4
1065	b.1x8	g.h1x7	0.877778	No	No	0	5	2
1066	G.HN.46	G.HN.49	0.875556	No	No	0	4	4
1067	G.s4h3.09	G.s4h3.10	0.838889	No	No	0	8	4
1068	g.h2x10	g.h2x13	0.838889	No	No	0	3	1
1069	g.h1x12	g.l1x1	0.777778	No	No	0	6	1
1070	6x14	6x15	0.776667	No	No	0	1	5
1071	6x28	6x31	0.766667	No	No	0	5	6
1072	6x37	6x38	0.76	Yes	No	0	8	7
1073	8x51	8x55	0.754444	No	No	0	9	6
1074	G.s4h3.11	G.s4h3.13	0.722222	No	No	0	9	4
1075	G.HN.49	G.HN.50	0.722222	No	No	0	4	5
1076	b.1x3	b.1x6	0.711111	No	No	0	1	3
1077	G.s4h3.12	G.s4h3.13	0.705556	No	No	0	8	4
1078	G.s3h2.01	G.s3h2.02	0.703333	No	No	0	9	9
1079	g.ctx6	g.h2x16	0.702222	Yes	No	0	6	4
1080	8x57	8x58	0.653333	No	No	0	7	7
1081	b.1x5	b.1x6	0.65	No	No	0	3	3
1082	3x22	3x23	0.636667	No	No	0	4	4
1083	b.lhb1x2	b.lhb1x3	0.628889	No	No	0	1	2
1084	b.l24x3	b.lhb1x1	0.622222	Yes	No	0	5	1
1085	6x17	G.H4.17	0.528889	No	No	0	3	3
1086	G.H5.22	G.H5.23	0.518889	No	No	0	5	4
1087	4x47	4x48	0.5	No	No	0	5	3
1088	1x36	1x37	0.5	No	No	0	5	4
1089	b.l8x3	b.l8x4	0.43	Yes	No	0	3	3
1090	6x27	6x31	0.404444	No	No	0	5	6
1091	G.s6h5.02	G.s6h5.03	0.382222	No	No	0	9	7
1092	b.1x14	g.h1x6	0.361111	No	No	0	4	4
1093	G.HN.10	G.HN.37	0.352222	No	No	0	4	3
1094	1x55	1x59	0.351111	No	No	0	5	6
1095	7x31	Lig	0.207778	No	Yes	0	2	0
1096	b.l21x6	b.l21x7	0.182222	No	No	0	3	5
1097	6x21	6x24	0.178889	No	No	0	5	5
1098	G.HN.35	G.HN.38	0.167778	No	No	0	4	3
1099	G.h1ha.01	G.h1ha.02	0.167778	No	No	0	8	4
1100	E3.C375	E3.H376	0.163333	No	No	0	4	2
1101	8x52	8x56	0.155556	No	No	0	6	6
1102	8x47	8x48	0.155556	No	No	0	9	6
1103	g.l1x3	g.l1x5	0.155556	No	No	0	1	4
1104	4x40	4x43	0.153333	No	No	0	6	4
1105	G.HN.33	g.ctx19	0.153333	No	No	0	4	8
1106	G.hfs2.02	b.l5x2	0.118889	No	No	0	6	6

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.S1.01	4.68861	4	2	6
2	G.S1.02	5.12111	4	3	5
3	G.H1.01	4.22644	5	3	9
4	G.H1.04	3.966	5	3	9
5	G.H1.08	3.76611	4	3	9
6	G.S2.05	5.77111	4	2	6
7	G.S2.06	6.16583	4	3	3
8	G.S2.08	8.39833	4	3	3
9	G.S3.01	4.98578	5	3	3
10	G.S3.03	8.15756	5	3	4
11	G.S3.04	8.46333	4	2	7
12	G.S3.05	3.71889	5	3	6
13	G.S3.06	7.82289	5	2	7
14	G.S3.07	3.57	4	3	5
15	G.s3h2.03	4.634	5	2	9
16	G.H2.02	4.73167	4	2	9
17	G.H2.06	5.1846	7	2	8
18	G.H2.07	5.32778	7	2	9
19	G.H2.09	6.72778	4	2	8
20	G.h2s4.01	6.75467	5	2	7
21	G.s4h3.04	4.62	7	6	8
22	G.s4h3.05	4.02917	4	6	8
23	G.H3.01	5.58611	4	0	9
24	G.H3.09	6.14315	6	9	9
25	G.H3.13	3.78911	5	9	8
26	G.H3.14	5.58139	4	9	5
27	G.H3.17	7.33185	6	2	4
28	G.H3.18	5.75244	5	21	5
29	G.S5.04	4.33333	4	0	8
30	G.S5.05	4.21	6	3	9
31	G.HG.04	5.44667	5	6	6
32	G.hgh4.02	6.44289	5	22	6
33	G.hgh4.05	9.40917	4	0	6
34	G.H4.03	5.24148	6	6	5
35	G.H4.10	10.6072	4	22	3
36	G.H4.15	5.22711	5	0	5
37	G.h4s6.02	5.70889	4	9	4
38	G.h4s6.11	4.36667	4	9	3
39	G.S6.02	5.83644	5	23	5
40	G.S6.05	4.51528	4	6	9
41	G.s6h5.01	5.9975	4	3	4
42	G.H5.03	6.0525	4	3	4
43	G.H5.08	6.45778	4	3	8
44	G.H5.20	4.63889	4	0	8
45	G.H5.25	4.06067	5	0	8
46	G.H5.26	7.72852	6	25	7
47	b.1x4	2.81056	4	0	8
48	b.lh12x2	5.66333	4	0	8
49	b.lhb1x11	4.05556	4	10	4
50	b.b1x3	5.04667	4	11	7
51	b.b1x6	7.36861	4	0	9
52	b.l1x3	8.25222	6	8	9
53	b.b2x1	8.00644	5	2	8
54	b.b2x5	6.98511	5	0	7
55	b.b3x3	3.348	5	0	8
56	b.l3x2	4.91089	5	8	9
57	b.b4x3	4.55944	4	16	7
58	b.b4x5	4.39361	4	20	7
59	b.b4x6	10.2402	6	8	9
60	b.l4x2	10.0406	4	11	4
61	b.b5x2	5.71944	4	0	7
62	b.b5x3	6.22111	6	8	9
63	b.b5x5	5.55111	4	20	5
64	b.b5x7	6.53528	4	0	7
65	b.l5x1	4.458	5	16	8
66	b.l5x5	7.60222	7	2	9
67	b.b6x5	3.87267	5	0	6
68	b.l6x5	5.72056	4	17	4
69	b.b7x1	5.64267	5	17	4
70	b.l7x2	5.24444	4	2	9
71	b.l7x4	3.42111	4	0	9
72	b.l7x5	3.31889	4	0	6
73	b.b8x4	5.662	5	16	6
74	b.l8x3	2.16056	4	0	3
75	b.b9x3	4.94056	4	0	6
76	b.l9x3	7.88667	5	12	9
77	b.l9x6	5.28431	8	2	8
78	b.l9x7	3.45556	4	12	7
79	b.b10x5	4.65889	6	0	9
80	b.b11x4	6.18833	4	12	9
81	b.l11x2	7.16167	4	12	9
82	b.b12x3	3.51472	4	5	8
83	b.b12x6	8.32048	7	12	8
84	b.b13x7	7.75978	5	5	7
85	b.l13x3	7.26037	6	5	9
86	b.l13x6	4.52311	5	2	9
87	b.l13x7	4.42733	5	5	9
88	b.b14x3	4.92556	4	5	5
89	b.b15x1	7.22644	5	5	9
90	b.b15x2	7.38667	4	4	6
91	b.b15x3	4.32583	4	5	9
92	b.l15x2	5.49028	4	0	9
93	b.b16x4	10.0733	4	5	6
94	b.b16x5	4.70733	5	0	5
95	b.b16x6	8.42704	6	5	8
96	b.b16x7	7.02167	4	18	9
97	b.b17x4	5.22333	4	18	5
98	b.b17x5	7.53111	4	4	7
99	b.b17x7	8.63306	4	4	8
100	b.l17x3	8.96167	6	4	9
101	b.l17x6	6.95083	4	2	9
102	b.b18x3	5.135	4	4	8
103	b.l18x1	5.74704	6	13	6
104	b.l18x2	5.80806	4	13	7
105	b.b19x2	7.13311	5	4	6
106	b.b19x4	5.57528	4	4	8
107	b.l19x1	6.43778	4	2	9
108	b.l19x2	5.95694	4	0	9
109	b.b20x4	10.1104	5	4	8
110	b.b20x6	5.84349	7	4	6
111	b.b21x1	7.39333	5	4	7
112	b.b21x5	5.60361	4	0	4
113	b.b21x7	5.41352	6	0	5
114	b.b22x5	5.26489	5	13	7
115	b.l22x5	5.33822	5	26	9
116	b.b23x6	6.83907	6	14	7
117	b.l23x1	7.87	4	0	6
118	b.b24x4	7.37583	4	14	6
119	b.b24x6	6.13306	4	14	8
120	b.l24x3	4.30111	4	0	5
121	b.b25x3	6.67528	4	14	5
122	b.l25x3	8.11444	5	10	9
123	b.l27x1	10.6341	7	2	9
124	b.l27x2	8.00639	4	10	9
125	b.b28x2	7.18	4	0	4
126	b.b28x3	3.75861	4	0	7
127	b.b28x4	7.70583	4	10	6
128	b.b28x6	8.344	5	10	9
129	b.b28x7	6.19417	4	11	9
130	g.h1x11	2.44861	4	0	9
131	g.l1x4	3.69533	5	4	8
132	g.h2x11	9.44917	4	13	6
133	g.ctx3	6.06867	5	0	9
134	g.ctx6	3.27044	5	0	6
135	g.ctx14	6.36722	4	0	9
136	g.ctx15	5.44194	4	11	9
137	g.ctx16	4.57806	8	11	8
138	g.ctx17	3.03028	4	0	7
139	Lig	6.73183	14	1	0
140	1x53	3.78167	4	7	9
141	1x60	4.42444	5	7	7
142	I1x50	4.03704	6	7	8
143	2x46	6.125	4	1	9
144	2x50	5.93578	5	1	9
145	2x57	4.34333	4	0	8
146	2x63	4.645	4	0	6
147	E1x50	6.62746	7	15	9
148	3x26	3.82306	4	19	7
149	3x32	8.57194	4	1	8
150	3x37	4.26917	4	1	8
151	3x42	6.49302	7	1	8
152	3x43	5.39806	4	1	8
153	3x50	6.15528	4	1	9
154	3x51	7.48378	5	0	9
155	4x50	7.66733	5	1	9
156	E2.R176	4.67	4	19	6
157	E2.R181	3.4775	4	19	4
158	5x39	6.41045	5	0	8
159	5x47	8.22926	6	1	8
160	5x48	5.42	4	1	7
161	5x51	4.32333	4	1	7
162	5x58	4.62365	7	1	9
163	5x62	4.0025	4	0	6
164	6x37	3.09194	4	0	8
165	6x44	4.6163	6	1	9
166	6x45	2.38417	4	0	7
167	6x48	7.03175	7	1	8
168	6x49	4.88556	4	0	7
169	6x51	6.95356	5	1	8
170	6x52	9.30489	5	1	7
171	7x42	7.15037	6	1	8
172	7x49	8.11417	4	1	9
173	7x53	5.00044	5	1	9
174	7x55	4.18311	5	0	6
175	8x50	5.32833	8	7	8
176	8x54	5.03111	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b28x5	g.ctx16	10.6747	5.72222	No	Yes	11	5	8
2	b.b1x6	b.b28x5	10.6201	3.48778	Yes	No	0	9	5
3	b.b1x6	b.b4x6	10.479	17.4611	Yes	Yes	0	9	9
4	b.b4x6	b.b5x3	19.6759	9.53778	Yes	Yes	8	9	9
5	G.HN.43	b.b5x3	19.3013	6.94667	No	Yes	0	9	9
6	G.HN.39	G.HN.43	19.1524	3.9	No	No	0	5	9
7	G.HN.39	b.b5x5	19.0872	5.26778	No	Yes	0	5	5
8	b.b2x3	b.b2x5	78.6864	4.91333	No	Yes	0	6	7
9	b.b26x2	b.b2x3	78.6666	5.4	No	No	0	7	6
10	b.b26x1	b.b26x2	78.6504	3.63111	No	No	0	9	7
11	b.b26x1	b.l27x1	78.6341	4.94111	No	Yes	0	9	9
12	b.b2x1	b.l27x1	76.4497	9.21667	Yes	Yes	2	8	9
13	b.b2x1	b.l3x1	76.5344	11.7744	Yes	No	2	8	9
14	b.l3x1	b.l5x5	76.6141	4.99111	No	Yes	2	9	9
15	b.l26x5	g.ctx15	12.2378	4.65889	No	Yes	0	5	9
16	b.l26x5	g.ctx4	99.6493	5.03111	No	No	0	5	7
17	g.ctx3	g.ctx4	99.6613	3.39889	Yes	No	0	9	7
18	b.l22x1	g.ctx3	100	7.68667	No	Yes	0	9	9
19	b.l22x1	g.ctx5	99.9033	4.33889	No	No	0	9	9
20	b.lhb1x11	g.ctx5	99.9145	4.24111	Yes	No	0	4	9
21	b.b28x6	b.lhb1x11	99.891	3.10111	Yes	Yes	10	9	4
22	b.b27x3	b.b28x6	49.9637	7.41222	No	Yes	0	8	9
23	b.b27x3	b.l25x3	50.0182	6.99778	No	Yes	0	8	9
24	b.l25x3	b.l27x2	99.7284	6.02	Yes	Yes	10	9	9
25	b.l25x4	b.l27x2	99.6417	7.24222	No	Yes	0	5	9
26	8x56	b.l25x4	99.6035	6.76	No	No	0	6	5
27	1x60	8x56	99.3613	6.9	Yes	No	0	7	6
28	1x60	I1x50	99.1151	4.27111	Yes	Yes	7	7	8
29	8x50	I1x50	98.8294	6.63222	Yes	Yes	7	8	8
30	1x53	8x50	49.3395	2.91222	Yes	Yes	7	9	8
31	1x53	7x55	49.1578	4.49	Yes	Yes	0	9	6
32	7x50	7x55	97.8933	2.16222	No	Yes	0	9	6
33	1x50	7x50	97.7878	6.69889	No	No	0	9	9
34	1x50	2x50	96.9429	7.62778	No	Yes	0	9	9
35	2x46	2x50	34.7132	5.73	Yes	Yes	1	9	9
36	2x46	3x43	30.9005	3.22889	Yes	Yes	1	9	8
37	3x43	7x53	44.9089	6.64111	Yes	Yes	1	8	9
38	3x50	7x53	43.0425	5.6	Yes	Yes	1	9	9
39	3x50	G.H5.23	34.9685	7.73778	Yes	No	0	9	4
40	G.H5.23	G.H5.25	34.4927	3.52556	No	Yes	0	4	8
41	G.H5.20	G.H5.25	34.5069	3.07556	Yes	Yes	0	8	8
42	G.H5.20	G.H5.26	33.5699	4.19444	Yes	Yes	0	8	7
43	G.H5.17	G.H5.26	31.4604	10.7533	No	Yes	0	6	7
44	G.H5.13	G.H5.17	19.035	11.37	No	No	0	6	6
45	b.b28x4	b.b28x6	49.9897	6.70222	Yes	Yes	10	6	9
46	b.b28x4	b.l25x3	49.8802	9.60667	Yes	Yes	10	6	9
47	8x50	8x54	49.397	3.92778	Yes	Yes	0	8	8
48	7x55	8x54	49.1578	8.93889	Yes	Yes	0	6	8
49	2x50	7x49	61.7009	5.68556	Yes	Yes	1	9	9
50	3x43	7x49	30.8018	7.93444	Yes	Yes	1	8	9
51	G.h2s4.01	b.l5x5	27.9773	10.2433	Yes	Yes	2	7	9
52	G.H1.04	G.S5.05	14.9503	3.49	Yes	Yes	3	9	9
53	G.S5.03	G.S5.05	20.6129	3.48778	No	Yes	0	6	9
54	G.H5.10	G.S5.03	21.5558	3.25	No	No	0	4	6
55	G.H5.10	G.S6.02	22.0273	5.33667	No	Yes	0	4	5
56	G.S6.02	G.h4s6.12	11.9561	9.72556	Yes	No	0	5	7
57	G.H5.17	G.h4s6.12	12.1914	5.55	No	No	0	6	7
58	G.H5.13	G.S6.02	11.9584	6.51444	No	Yes	0	6	5
59	b.l5x5	b.l7x2	47.6224	8.09667	Yes	Yes	2	9	9
60	G.s3h2.03	b.l7x2	19.7431	3.25111	Yes	Yes	2	9	9
61	G.H2.07	G.h2s4.01	28.0731	3.78667	Yes	Yes	2	9	7
62	G.H2.07	b.l7x2	27.87	4.55556	Yes	Yes	2	9	9
63	G.H2.07	b.l9x6	40.1271	3.85889	Yes	Yes	2	9	8
64	G.s3h2.03	b.l9x6	19.3209	5.13444	Yes	Yes	2	9	8
65	G.H2.06	b.l9x6	55.4005	3.31667	Yes	Yes	2	8	8
66	G.H2.04	G.H2.07	18.1479	5.11111	No	Yes	0	9	9
67	G.H2.04	G.H3.08	17.9728	4.04778	No	No	0	9	5
68	G.H2.06	b.l17x6	27.9199	8.60444	Yes	Yes	2	8	9
69	G.H2.06	b.l19x1	27.92	3.07222	Yes	Yes	2	8	9
70	G.H3.08	G.S4.04	17.8876	5.27778	No	No	0	5	7
71	G.H3.09	G.S4.04	10.5581	16.3144	Yes	No	0	9	7
72	3x43	6x44	16.6635	3.78778	Yes	Yes	1	8	9
73	b.l17x5	b.l17x6	27.8058	3.92556	No	Yes	2	6	9
74	b.l17x5	b.l19x2	55.3431	3.59778	No	Yes	0	6	9
75	b.b19x6	b.l19x2	30.7076	3.92556	No	Yes	0	9	9
76	b.b19x6	b.l17x3	30.4451	13.6378	No	Yes	0	9	9
77	b.b20x6	b.l17x3	22.7978	2.89	Yes	Yes	4	6	9
78	b.b17x7	b.b20x6	31.8802	10.2411	Yes	Yes	4	8	6
79	b.b17x7	b.b21x1	21.8586	5.30889	Yes	Yes	4	8	7
80	b.1x19	b.b21x1	18.7031	7.01333	No	Yes	0	6	7
81	b.1x15	b.1x19	14.4799	4.59111	No	No	0	7	6
82	b.1x15	g.h1x11	12.3917	0.953333	No	Yes	0	7	9
83	b.1x11	g.h1x11	10.3271	3.07556	No	Yes	0	8	9
84	b.l17x5	b.l19x1	27.7987	3.76111	No	Yes	2	6	9
85	b.b20x2	b.l19x2	24.1127	5.62222	No	Yes	0	6	9
86	b.b20x2	b.b20x4	23.5874	6.46778	No	Yes	0	6	8
87	b.b20x4	b.b20x6	22.7978	4.86889	Yes	Yes	4	8	6
88	b.b4x5	b.b5x5	16.9921	6.48111	Yes	Yes	20	7	5
89	b.b2x4	b.b6x5	15.862	3.27	No	Yes	0	6	6
90	b.b10x4	b.b2x4	15.7103	14.5433	No	No	0	6	6
91	b.b2x5	b.b3x2	11.2523	8.60556	Yes	No	0	7	5
92	b.l26x3	b.l26x5	87.4016	7.24	No	No	0	7	5
93	b.l26x1	b.l26x3	87.3454	5.30111	No	No	27	7	7
94	b.b2x5	b.l26x1	87.3549	11.5922	Yes	No	0	7	7
95	b.b10x2	b.b10x4	15.5594	3.86889	No	No	0	6	6
96	b.b10x2	b.b6x2	10.8471	3.19222	No	No	0	6	8
97	b.b10x3	b.b6x2	10.6729	3.94333	No	No	0	8	8
98	b.b19x2	b.b20x6	12.6654	9.40889	Yes	Yes	4	6	6
99	b.b15x2	b.b19x2	11.613	9.46778	Yes	Yes	4	6	6
100	b.b15x2	b.b16x5	12.6702	3.64222	Yes	Yes	0	6	5
101	b.b16x7	b.l16x2	10.5599	3.96889	Yes	No	0	9	9
102	b.b16x5	b.b17x4	10.5597	2.96889	Yes	Yes	0	5	5
103	3x36	Lig	10.9675	6.10889	No	Yes	1	7	0
104	3x36	6x48	14.3827	4.06111	No	Yes	1	7	8
105	6x48	7x45	30.5815	11.5511	Yes	No	0	8	9
106	7x45	7x49	30.8057	10.2922	No	Yes	0	9	9
107	6x52	Lig	11.2298	8.54111	Yes	Yes	1	7	0
108	6x48	6x52	12.7361	6.01444	Yes	Yes	1	8	7
109	b.b3x2	b.b4x6	11.1942	5.82	No	Yes	0	5	9
110	g.ctx15	g.ctx16	11.1116	3.04778	Yes	Yes	11	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x63	Lig	7.29444	0	Yes	Yes	6	0	1	0
3x32	Lig	14.0289	1	Yes	Yes	8	0	1	0
3x33	Lig	7.48444	0	No	Yes	8	0	1	0
3x36	Lig	6.10889	1	No	Yes	7	0	1	0
3x37	Lig	4.15111	1	Yes	Yes	8	0	1	0
E2x52	Lig	4.94778	0	No	Yes	6	0	1	0
5x43	Lig	5.96333	0	No	Yes	8	0	1	0
5x461	Lig	3.04222	1	No	Yes	8	0	1	0
6x51	Lig	16.1133	1	Yes	Yes	8	0	1	0
6x52	Lig	8.54111	1	Yes	Yes	7	0	1	0
7x38	Lig	4.79333	1	No	Yes	7	0	1	0
7x42	Lig	8.40333	1	Yes	Yes	8	0	1	0
2x56	3x32	6.97667	1	No	Yes	8	8	2	1
2x56	7x42	3.22667	1	No	Yes	8	8	2	1
2x57	7x42	6.38333	0	Yes	Yes	8	8	2	1
2x60	7x42	4.15	0	No	Yes	7	8	2	1
2x63	E1x50	8.03889	0	Yes	Yes	6	9	1	2
2x64	7x35	3.70778	0	No	No	7	6	1	2
2x64	7x39	7.18222	0	No	No	7	8	1	2
3x29	E2x52	4.58	0	No	No	7	6	2	1
3x32	3x36	2.94	1	Yes	No	8	7	1	1
3x32	7x42	10.3422	1	Yes	Yes	8	8	1	1
3x33	4x57	4.84778	0	No	No	8	8	1	2
3x36	6x48	4.06111	1	No	Yes	7	8	1	2
3x37	4x53	3.43778	1	Yes	No	8	8	1	2
3x37	4x56	5.57333	1	Yes	No	8	8	1	2
3x37	5x461	3.91444	1	Yes	No	8	8	1	1
5x39	5x43	8.19556	0	Yes	No	8	8	2	1
5x44	6x52	3.74667	1	No	Yes	7	7	2	1
5x47	6x48	3.56444	1	Yes	Yes	8	8	2	2
5x47	6x52	19.4089	1	Yes	Yes	8	7	2	1
6x48	6x52	6.01444	1	Yes	Yes	8	7	2	1
6x51	6x52	8.81333	1	Yes	Yes	8	7	1	1
6x51	7x37	2.93111	1	Yes	No	8	6	1	2
6x51	7x38	5.37	1	Yes	No	8	7	1	1
7x39	7x42	10.3967	0	No	Yes	8	8	2	1
2x64	Lig	3.16556	0	No	Yes	7	0	1	0
2x63	E2.D185	1.91556	0	Yes	No	6	0	1	2
6x51	6x55	1.54	1	Yes	No	8	8	1	2
2x63	E2.A186	1.33111	0	Yes	No	6	0	1	2
7x31	Lig	0.207778	0	No	Yes	2	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Consensus	5ht1a_on	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
80.00	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
80.00	Consensus	gi_5ht	Orthosteric Ligand	8FYT-5-HT_1A-LSD-Gi1/β1/γ1 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2 7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2 7E32-5-HT_1D-Serotonin-Gi1/β1/γ2 7XTA-5-HT₄-Serotonin-Gi1/β1/γ2 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1 8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2 8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1 8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2 8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1 7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1 7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2 7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1 7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
78.57	Single	8PJK	ST171	8PJK-5-HT_1A-ST171-Gi1/β1/γ1
75.00	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
73.33	Single	8GFY	Constrained Epinephrine	8GFY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
73.33	Single	8GG2	Constrained Epinephrine	8GG2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
72.22	Single	8FYL	Vilazodone	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1
71.43	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/β1/γ2
71.43	Single	8GE1	Constrained Epinephrine	8GE1-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GE4	Constrained Epinephrine	8GE4-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GE6	Constrained Epinephrine	8GE6-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GE7	Constrained Epinephrine	8GE7-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GE8	Constrained Epinephrine	8GE8-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GEF	Constrained Epinephrine	8GEF-β₂-Constrained Epinephrine-Gs/β1/γ2
71.43	Single	8GGV	Constrained Epinephrine	8GGV-β₂-Constrained Epinephrine
71.43	Single	9CBL	Epinephrine	9CBL-α_2a-Epinephrine-Gi1/β1/γ2
68.75	Single	7W6P	N-pyridin-4-ylisoquinolin-4-amine	7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2
68.75	Single	7W7E	PubChem 164946676	7W7E-α_2a-PubChem 164946676-Go/β1/γ2
68.75	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
68.75	Consensus	amine_on_gp	Orthosteric Ligand	5ht_on_gp adrenergic_on_gp dopamine_on_gp histamine_on_gp muscarinic_on_gp trace-amine_on_gp
68.75	Consensus	beta2_on	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
68.75	Consensus	beta2_on_gp	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2
68.75	Consensus	gs_adrenergic	Orthosteric Ligand	7DHI-β₂-Salbutamol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2 7JJO-β₁-Isoprenaline-Gs/β1/γ2 6NI3-β₂-BI167107-Gs/β1/γ2 8DCR-β₁-Dobutamine-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7DH5-β₃-Mirabegron-Gs/β1/γ2
68.75	Consensus	ta1_on_gp	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
68.75	Consensus	trace-amine_on_gp	Orthosteric Ligand	ta1_on_gp
66.67	Single	4QKX	35V	4QKX-β₂-35V
66.67	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
66.67	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
66.67	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
66.67	Single	8FY8	5-MeO-DMT	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
66.67	Single	8GE3	Constrained Epinephrine	8GE3-β₂-Constrained Epinephrine-Gs/β1/γ2
66.67	Single	8GE9	Constrained Epinephrine	8GE9-β₂-Constrained Epinephrine-Gs/β1/γ2
66.67	Single	8GEC	Constrained Epinephrine	8GEC-β₂-Constrained Epinephrine-Gs/β1/γ2
66.67	Single	8GEE	Constrained Epinephrine	8GEE-β₂-Constrained Epinephrine-Gs/β1/γ2
66.67	Single	8GFV	Constrained Epinephrine	8GFV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GFW	Constrained Epinephrine	8GFW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GFX	Constrained Epinephrine	8GFX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GFZ	Constrained Epinephrine	8GFZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GG0	Constrained Epinephrine	8GG0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GG1	Constrained Epinephrine	8GG1-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GG3	Constrained Epinephrine	8GG3-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GG4	Constrained Epinephrine	8GG4-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GG6	Constrained Epinephrine	8GG6-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GG9	Constrained Epinephrine	8GG9-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8GGI	Constrained Epinephrine	8GGI-β₂-Constrained Epinephrine
66.67	Single	8GGJ	Constrained Epinephrine	8GGJ-β₂-Constrained Epinephrine
66.67	Single	8GGK	Constrained Epinephrine	8GGK-β₂-Constrained Epinephrine
66.67	Single	8GGN	Constrained Epinephrine	8GGN-β₂-Constrained Epinephrine
66.67	Single	8GGO	Constrained Epinephrine	8GGO-β₂-Constrained Epinephrine
66.67	Single	8GGU	Constrained Epinephrine	8GGU-β₂-Constrained Epinephrine
66.67	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/β1/γ2
66.67	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2
66.67	Single	8UNQ	Constrained Epinephrine	8UNQ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8UNY	Constrained Epinephrine	8UNY-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
66.67	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2
66.67	Single	9PQD	(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole	9PQD-α_2a-(6m)-1-methyl-6-(1,2,5,6-tetrahydropyridin-3-yl)-1h-indole
66.67	Consensus	adrenergic_on	Orthosteric Ligand	alpha_on beta_on
66.67	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
66.67	Consensus	dopamine_on	Orthosteric Ligand	d2_on d1_on d3_on d4_on d5_on
66.67	Consensus	dopamine_on_gp	Orthosteric Ligand	d2_on_gp d1_on_gp d3_on_gp d4_on_gp d5_on_gp
64.71	Single	3D4S	Timolol	3D4S-β₂-Timolol
64.71	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
64.71	Single	8FYE	4-F,5-MeO-PyrT	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
64.71	Single	8FYT	LSD	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
64.71	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off
64.71	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin
64.71	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
64.71	Consensus	beta3_on_gp	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/β1/γ2 7XJH-β₃-Isoproterenol-Gs/β1/γ2 7XJI-β₃-Solabegron-Gs/β1/γ2
64.71	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
64.71	Consensus	beta_on_gp	Orthosteric Ligand	beta1_on_gp beta2_on_gp beta3_on_gp
64.71	Consensus	d2_on_gp	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
64.29	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)
64.29	Single	8GGA	Constrained Epinephrine	8GGA-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
64.29	Single	8GGR	Constrained Epinephrine	8GGR-β₂-Constrained Epinephrine
64.29	Single	8GGW	Constrained Epinephrine	8GGW-β₂-Constrained Epinephrine
64.29	Single	8GH0	Constrained Epinephrine	8GH0-β₂-Constrained Epinephrine
64.29	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
64.29	Consensus	h1_on_gp	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
63.16	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
63.16	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/β1/γ2
63.16	Single	8ZSP	LSD	8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
62.50	Single	2RH1	S-Carazolol	2RH1-β₂-S-Carazolol
62.50	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
62.50	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
62.50	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
62.50	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
62.50	Single	6PS3	S-Carvedilol	6PS3-β₂-S-Carvedilol
62.50	Single	7BVQ	S-Carazolol	7BVQ-β₁-S-Carazolol
62.50	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/β1/γ2
62.50	Single	7XK9	Constrained Isoproterenol	7XK9-β₂-Constrained Isoproterenol-Na
62.50	Single	7XKA	Constrained Epinephrine	7XKA-β₂-Constrained Epinephrine
62.50	Single	8GDZ	Constrained Epinephrine	8GDZ-β₂-Constrained Epinephrine-Gs/β1/γ2
62.50	Single	8GEB	Constrained Epinephrine	8GEB-β₂-Constrained Epinephrine-Gs/β1/γ2
62.50	Single	8GEG	Constrained Epinephrine	8GEG-β₂-Constrained Epinephrine-Gs/β1/γ2
62.50	Single	8GGB	Constrained Epinephrine	8GGB-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
62.50	Single	8UNN	Constrained Epinephrine	8UNN-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
62.50	Single	8UNP	Constrained Epinephrine	8UNP-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
62.50	Single	9DYD	Asenapine	9DYD-5-HT_1A-Asenapine-Go/β1/γ2
62.50	Single	9DYF	Asenapine	9DYF-5-HT_1A-Asenapine-Gi1/β1/γ2
62.50	Single	9F33	FOB02-04A	9F33-D₃-FOB02-04A-Go/β1/γ2
62.50	Single	9F34	FOB02-04A	9F34-D₃-FOB02-04A-Go/β1/γ2
62.50	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on
62.50	Consensus	5ht1_on_gp	Orthosteric Ligand	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp
62.50	Consensus	5ht1e_on_gp	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
62.50	Consensus	5ht5_on_gp	Orthosteric Ligand	5ht5a_on_gp
62.50	Consensus	5ht5a_on_gp	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
62.50	Consensus	adrenergic_off	Orthosteric Ligand	alpha_off beta_off
62.50	Consensus	adrenergic_on_gp	Orthosteric Ligand	alpha_on_gp beta_on_gp
62.50	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
62.50	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
62.50	Consensus	alpha_on_gp	Orthosteric Ligand	alpha1_on_gp alpha2_on_gp
62.50	Consensus	amine_off	Orthosteric Ligand	5ht_off adrenergic_off dopamine_off histamine_off muscarinic_off
62.50	Consensus	amine_offon	Orthosteric Ligand	amine_off amine_on
62.50	Consensus	amine_offon_gp	Orthosteric Ligand	amine_on_gp amine_off
62.50	Consensus	amine_on	Orthosteric Ligand	5ht_on adrenergic_on dopamine_on histamine_on muscarinic_on trace-amine_on
62.50	Consensus	beta2_off	Orthosteric Ligand	2RH1-β₂-S-Carazolol 6PS3-β₂-S-Carvedilol 6PS5-β₂-S-Propranolol 3D4S-β₂-Timolol 3NY8-β₂-ICI118-551 3NY9-β₂-ICI118-551 6PRZ-β₂-S-Alprenolol
62.50	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
62.50	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2
62.50	Consensus	gi_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
62.50	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_trace-amine
62.50	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2 8W88-TA1-SEP-363856-Gs/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8ZSP-TA1-LSD-chim(NtGi1L-Gs-CtGq)/β1/γ2
62.50	Consensus	trace-amine_on	Orthosteric Ligand	ta1_on
61.11	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
61.11	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
61.11	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
61.11	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2
61.11	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
61.11	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
61.11	Single	8S2T	Isoprenaline	8S2T-β₁-Isoprenaline-chim(NtGi1-Gs)/β1/γ2
61.11	Consensus	beta1_on	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
61.11	Consensus	beta1_on_gp	Orthosteric Ligand	8DCR-β₁-Dobutamine-Gs/β1/γ2 7S0F-β₁-Isoprenaline-Gi1/β1/γ2
60.00	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
60.00	Single	6PS0	S-Carazolol	6PS0-β₂-S-Carazolol
60.00	Single	6PS4	ICI118-551	6PS4-β₂-ICI118-551
60.00	Single	6PS5	S-Propranolol	6PS5-β₂-S-Propranolol
60.00	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/β1/γ2
60.00	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/β1/γ2
60.00	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/β1/γ2
60.00	Single	7UL3	Famotidine	7UL3-H₂-Famotidine
60.00	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
60.00	Single	8GEA	Constrained Epinephrine	8GEA-β₂-Constrained Epinephrine-Gs/β1/γ2
60.00	Single	8GED	Constrained Epinephrine	8GED-β₂-Constrained Epinephrine-Gs/β1/γ2
60.00	Single	8GG5	Constrained Epinephrine	8GG5-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
60.00	Single	8GG7	Constrained Epinephrine	8GG7-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
60.00	Single	8GG8	Constrained Epinephrine	8GG8-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
60.00	Single	8GGL	Constrained Epinephrine	8GGL-β₂-Constrained Epinephrine
60.00	Single	8GGM	Constrained Epinephrine	8GGM-β₂-Constrained Epinephrine
60.00	Single	8GGP	Constrained Epinephrine	8GGP-β₂-Constrained Epinephrine
60.00	Single	8GGQ	Constrained Epinephrine	8GGQ-β₂-Constrained Epinephrine
60.00	Single	8GGS	Constrained Epinephrine	8GGS-β₂-Constrained Epinephrine
60.00	Single	8GGT	Constrained Epinephrine	8GGT-β₂-Constrained Epinephrine
60.00	Single	8GGX	Constrained Epinephrine	8GGX-β₂-Constrained Epinephrine
60.00	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/β1/γ2
60.00	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
60.00	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/β1/γ2
60.00	Single	8UNL	Constrained Epinephrine	8UNL-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
60.00	Single	8UNM	Constrained Epinephrine	8UNM-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
60.00	Single	8UNO	Constrained Epinephrine	8UNO-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
60.00	Single	8UNW	Constrained Epinephrine	8UNW-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
60.00	Single	8V6U	PubChem 171392456	8V6U-5-HT_2A-PubChem 171392456-chim(NtGi2-Gs-CtGq)/β1/γ2
60.00	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/β1/γ2
60.00	Single	9AS5	Mescaline	9AS5-5-HT_2A-Mescaline
60.00	Single	9AS6	Mescaline	9AS6-5-HT_2A-Mescaline-chim(NtGi1-Gs-CtGq)/β1/γ2
60.00	Single	9JKQ	METH	9JKQ-TA1-METH-Gs/β1/γ2
60.00	Consensus	5ht_on_gp	Orthosteric Ligand	5ht1_on_gp 5ht2_on_gp 5ht4_on_gp 5ht5_on_gp 5ht6_on_gp 5ht7_on_gp
60.00	Consensus	d3_on	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
60.00	Consensus	d3_on_gp	Orthosteric Ligand	7CMV-D₃-PD128907-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2
58.82	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
58.82	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
58.82	Single	5D5A	S-Carazolol	5D5A-β₂-S-Carazolol
58.82	Single	5D5B	S-Carazolol	5D5B-β₂-S-Carazolol
58.82	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
58.82	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
58.82	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
58.82	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/β1/γ2
58.82	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/β1/γ2
58.82	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
58.82	Single	9IJD	Carazolol	9IJD-β₃-Carazolol-chim(NtGi1-Gs)/β1/γ2
58.82	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht1_off
58.82	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCW-β₁-S-Carazolol 2YCZ-β₁-Iodocyanopindolol 5A8E-β₁-7-Methylcyanopindolol-Na 3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na 3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
58.82	Consensus	d1_on_gp	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
58.82	Consensus	d5_on_gp	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2
58.82	Consensus	gi_dopamine	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/β1/γ2 7CMV-D₃-PD128907-Gi1/β1/γ2 7CMU-D₃-Pramipexole-Gi1/β1/γ2 8IRS-D₂-Rotigotine-Gi1/β1/γ2 8IRT-D₃-Rotigotine-Gi1/β1/γ2
58.82	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2
58.82	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
57.89	Single	9MD1	Buspirone	9MD1-5-HT_1A-Buspirone-Gz/β1/γ2
57.14	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
57.14	Single	8GGY	Constrained Epinephrine	8GGY-β₂-Constrained Epinephrine
57.14	Single	9IJE	Epinephrine	9IJE-β₃-Epinephrine-chim(NtGi1-Gs)/β1/γ2
57.14	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/β1/γ2
56.25	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
56.25	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
56.25	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
56.25	Single	3NY8	ICI118-551	3NY8-β₂-ICI118-551
56.25	Single	3NYA	S-Alprenolol	3NYA-β₂-S-Alprenolol
56.25	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
56.25	Single	4GBR	S-Carazolol	4GBR-β₂-S-Carazolol
56.25	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
56.25	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
56.25	Single	6PRZ	S-Alprenolol	6PRZ-β₂-S-Alprenolol
56.25	Single	6PS1	Timolol	6PS1-β₂-Timolol
56.25	Single	6PS2	S-Alprenolol	6PS2-β₂-S-Alprenolol
56.25	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
56.25	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/β1/γ2
56.25	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/β1/γ2
56.25	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/β1/γ2
56.25	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2
56.25	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
56.25	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/β1/γ2
56.25	Single	8GEH	Constrained Epinephrine	8GEH-β₂-Constrained Epinephrine-Gs/β1/γ2
56.25	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
56.25	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2
56.25	Single	8UGY	Mianserin	8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1
56.25	Single	8UNR	Constrained Epinephrine	8UNR-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
56.25	Single	8UNU	Constrained Epinephrine	8UNU-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
56.25	Single	8UNV	Constrained Epinephrine	8UNV-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
56.25	Single	8UNZ	Constrained Epinephrine	8UNZ-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
56.25	Single	8UO2	Constrained Epinephrine	8UO2-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
56.25	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2
56.25	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
56.25	Single	8ZSS	RO5263397	8ZSS-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
56.25	Single	9AS1	DMT	9AS1-5-HT_2A-DMT
56.25	Single	9CBM	Dexmedetomidine	9CBM-α_2a-Dexmedetomidine-Gi1/β1/γ2
56.25	Single	9JEA	Atropine	9JEA-M₁-Atropine
56.25	Single	9PLN	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLN-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine
56.25	Single	9PLO	N-(5-methylnaphthalen-1-yl)pyridin-4-amine	9PLO-α_2a-N-(5-methylnaphthalen-1-yl)pyridin-4-amine-Go/β1/γ2
56.25	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
56.25	Consensus	5ht1d_on_gp	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/β1/γ2
56.25	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide
56.25	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
56.25	Consensus	5ht5a_on	Orthosteric Ligand	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/β1/γ2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/β1/γ2
56.25	Consensus	alpha2_on	Orthosteric Ligand	alpha2b_on
56.25	Consensus	alpha2_on_gp	Orthosteric Ligand	alpha2b_on_gp
56.25	Consensus	alpha2b_on	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
56.25	Consensus	alpha2b_on_gp	Orthosteric Ligand	6K42-α_2b-Dexmedetomidine-Gi1/β1/γ2
56.25	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
56.25	Consensus	dopamine_off	Orthosteric Ligand	d2_off d3_off
56.25	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
56.25	Consensus	gs_trace-amine	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/β1/γ2 8JLJ-TA1-T1AM-chim(NtGi1-Gs)/β1/γ2 8JLO-TA1-Ulotaront-Gs/β1/γ2 8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2 8WC7-TA1-ZH8667-chim(NtGi1-Gs)/β1/γ2 8JLR-TA1-A77636-chim(NtGi1-Gs)/β1/γ2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2 8W87-TA1-METH-chim(NtGi1L-Gs)/β1/γ2 8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2 8JLP-TA1-Ralmitaront-Gs/β1/γ2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/β1/γ2
55.56	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
55.56	Single	4LDE	BI167107	4LDE-β₂-BI167107
55.56	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
55.56	Single	6H7N	S-Xamoterol	6H7N-β₁-S-Xamoterol
55.56	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
55.56	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/β1/γ2
55.56	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/β1/γ2
55.56	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/β1/γ2
55.56	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/β1/γ2
55.56	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
55.56	Single	9GL2	Befiradol	9GL2-5-HT_1A-Befiradol-Gs/β1/γ2
55.56	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
55.00	Single	4AMJ	S-Carvedilol	4AMJ-β₁-S-Carvedilol
55.00	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
55.00	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
55.00	Single	8PKM	Befiradol	8PKM-5-HT_1A-Befiradol-Gi1/β1/γ1
55.00	Single	9M4T	Silodosin	9M4T-Alpha1A-Silodosin
53.33	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
53.33	Single	6OBA	S-Alprenolol	6OBA-β₂-S-Alprenolol-GTPL11074
53.33	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/β1/γ2
53.33	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/β1/γ1
53.33	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/β1/γ2
53.33	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/β1/γ2
53.33	Single	8FYX	Buspirone	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
53.33	Single	8GGC	Constrained Epinephrine	8GGC-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
53.33	Single	8GGZ	Constrained Epinephrine	8GGZ-β₂-Constrained Epinephrine
53.33	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/β1/γ2
53.33	Single	8TZQ	L-Dopamine	8TZQ-D₂-L-Dopamine-Go/β1/γ2
53.33	Single	8UNS	Constrained Epinephrine	8UNS-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
53.33	Single	8UNT	Constrained Epinephrine	8UNT-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
53.33	Single	8UNX	Constrained Epinephrine	8UNX-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
53.33	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/β1/γ2
53.33	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
53.33	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
53.33	Single	8YUT	Amthamine	8YUT-H₂-Amthamine-Gs/β1/γ2
53.33	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2 8UGY-5-HT_1E-Mianserin-Gi1/β1/γ1 8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
53.33	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
53.33	Consensus	alpha2_off	Orthosteric Ligand	alpha2c_off
53.33	Consensus	gs_5ht	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2 7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2 7XT8-5-HT₄-Serotonin-Gs/β1/γ2
52.94	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
52.94	Single	2YCW	S-Carazolol	2YCW-β₁-S-Carazolol
52.94	Single	5D6L	S-Carazolol	5D6L-β₂-S-Carazolol
52.94	Single	5JQH	S-Carazolol	5JQH-β₂-S-Carazolol
52.94	Single	5X7D	S-Carazolol	5X7D-β₂-S-Carazolol-Cmpd-15
52.94	Single	6E67	BI167107	6E67-β₂-BI167107-Gs(CT)
52.94	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
52.94	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
52.94	Single	9ARY	Serotonin	9ARY-5-HT_2A-Serotonin-chim(NtGi1-Gs-CtGq)/β1/γ2
52.94	Single	9ARZ	2-bromo-LSD	9ARZ-5-HT_2A-2-bromo-LSD
52.94	Single	9K07	DSO-5a	9K07-BB₃-DSO-5a-chim(NtGi2L-Gs-CtGq)/β1/γ2
52.94	Single	9MQK	Isoquinuclidine	9MQK-κ-Isoquinuclidine
52.94	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
52.94	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/β1/γ2 7CKY-D₁-PW0464-Gs/β1/γ2 8IRR-D₁-Rotigotine-Gs/β1/γ2 7JV5-D₁-SKF81297-Gs/β1/γ2 7JVP-D₁-SKF83959-Gs/β1/γ2 7X2D-D₁-Tavapadon-Gs/β1/γ2 7CKX-D₁-A77636-Gs/β1/γ2 7JVQ-D₁-Apomorphine-Gs/β1/γ2 7CKW-D₁-Fenoldopam-Gs/β1/γ2
52.94	Consensus	d4_on	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
52.94	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
52.94	Consensus	m3_on_gp	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2 8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
52.63	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
52.63	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
52.63	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
52.63	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
52.63	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/β1/γ2
52.63	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/β1/γ2
52.63	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2
52.63	Single	8E9Y	Clozapine-N-oxide	8E9Y-M₃-Clozapine-N-oxide-chim(NtGi2L-Gs-CtGq)/β1/γ2
52.63	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
52.63	Single	9AS0	2-bromo-LSD	9AS0-5-HT_2A-2-bromo-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
52.63	Single	9DYE	Buspirone	9DYE-5-HT_1A-Buspirone-Go/β1/γ2
52.63	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
50.00	Single	2YDV	NECA	2YDV-A_2A-NECA
50.00	Single	3NY9	ICI118-551	3NY9-β₂-ICI118-551
50.00	Single	3P0G	BI167107	3P0G-β₂-BI167107
50.00	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
50.00	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/β1/γ2
50.00	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
50.00	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
50.00	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
50.00	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
50.00	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
50.00	Single	5G53	NECA	5G53-A_2A-NECA-Gs
50.00	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
50.00	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
50.00	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
50.00	Single	6FUF	All-trans-Retinal	6FUF-Rhodopsin-All-trans-Retinal-Go
50.00	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/β1/γ2
50.00	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/β1/γ2
50.00	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
50.00	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/β1/γ2
50.00	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
50.00	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
50.00	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
50.00	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/β1/γ2
50.00	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/β1/γ2
50.00	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/β1/γ2
50.00	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/β1/γ2
50.00	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/β1/γ2
50.00	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/β1/γ2
50.00	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/β1/γ2
50.00	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/β1/γ2
50.00	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
50.00	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
50.00	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/β1/γ2
50.00	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
50.00	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/β1/γ2
50.00	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/β1/γ2
50.00	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/β1/γ2
50.00	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/β1/γ2
50.00	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/β1/γ2
50.00	Single	8U02	L-Dopamine	8U02-D₂-L-Dopamine-Go/β1/γ2
50.00	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/β1/γ2
50.00	Single	8UO0	Constrained Epinephrine	8UO0-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
50.00	Single	8UO1	Constrained Epinephrine	8UO1-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
50.00	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/β1/γ2
50.00	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/β1/γ2
50.00	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
50.00	Single	8YN3	Histamine	8YN3-H₂-Histamine-Gs/β1/γ2
50.00	Single	9AS3	LSD	9AS3-5-HT_2A-LSD
50.00	Single	9AS4	LSD	9AS4-5-HT_2A-LSD-chim(NtGi1-Gs-CtGq)/β1/γ2
50.00	Single	9MQI	Isoquinuclidine	9MQI-μ-Isoquinuclidine
50.00	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
50.00	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
50.00	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
50.00	Consensus	alpha1_on_gp	Orthosteric Ligand	alpha1a_on_gp
50.00	Consensus	alpha1a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
50.00	Consensus	alpha1a_on_gp	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2 7EJ8-α_2a-Brimonidine-Go/β1/γ2 7EJA-α_2a-Dexmedetomidine-Go/β1/γ2 7EJK-α_2a-Oxymetazoline-Go/β1/γ2 7W6P-α_2a-N-pyridin-4-ylisoquinolin-4-amine-Go/β1/γ2 7W7E-α_2a-PubChem 164946676-Go/β1/γ2
50.00	Consensus	d4_on_gp	Orthosteric Ligand	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/β1/γ2
50.00	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl-Scopolamine 5ZHP-M₃-PubChem 134828589
50.00	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
47.83	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2
47.62	Single	8WDT	photoNECA	8WDT-A_2A-photoNECA
47.62	Single	9BUY	LM189	9BUY-β₂-LM189-Gi1/β1/γ2
47.37	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
47.37	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
47.37	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
47.37	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
47.37	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
47.37	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
47.37	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/β1/γ2
47.37	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
47.37	Single	9M4Q	Doxazosin	9M4Q-Alpha1A-Doxazosin
47.37	Single	9MQL	Isoquinuclidine	9MQL-κ-Isoquinuclidine
47.37	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
47.37	Consensus	5ht1f_on_gp	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/β1/γ2
47.37	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_muscarinic gi_adrenergic gi_dopamine gi_histamine
47.37	Consensus	gi_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2 7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
47.37	Consensus	mop_on	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
47.37	Consensus	mop_on_gp	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2
47.37	Consensus	nk1_off	Orthosteric Ligand	6HLP-NK₁-Netupitant 6HLO-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
47.06	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
47.06	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
47.06	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
47.06	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
47.06	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
47.06	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
47.06	Single	4U16	N-Methyl-Scopolamine	4U16-M₃-N-Methyl-Scopolamine
47.06	Single	5YC8	N-Methyl-Scopolamine	5YC8-M₂-N-Methyl-Scopolamine
47.06	Single	5ZK8	N-Methyl-Scopolamine	5ZK8-M₂-N-Methyl-Scopolamine
47.06	Single	5ZKC	N-Methyl-Scopolamine	5ZKC-M₂-N-Methyl-Scopolamine
47.06	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/β1/γ2
47.06	Single	7BU7	BI167107	7BU7-β₁-BI167107
47.06	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/β1/γ2
47.06	Single	7LJC	SKF-81297	7LJC-D₁-SKF-81297-Mevidalen-Gs/β1/γ2
47.06	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/β1/γ2
47.06	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
47.06	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/β1/γ2
47.06	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
47.06	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/β1/γ2
47.06	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/β1/γ2
47.06	Single	8JXR	LSD	8JXR-D₁-LSD
47.06	Single	8UH3	Setiptiline	8UH3-5-HT_1E-Setiptiline-Gi1/β1/γ1
47.06	Single	8UWL	Lisuride	8UWL-5-HT_2A-Lisuride-chim(NtGi2-Gs-CtGq)/β1/γ2
47.06	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
47.06	Single	8XVK	Ambrisentan	8XVK-ET_A-Ambrisentan
47.06	Single	8YN8	Proxyfan	8YN8-H₃-Proxyfan-Go/β1/γ2
47.06	Single	9CHX	S-Carazolol	9CHX-β₂-S-Carazolol
47.06	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
47.06	Consensus	5ht7_on_gp	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/β1/γ2
47.06	Consensus	gi_orexin	Orthosteric Ligand	7SQO-OX₂-TAK-925-Gi1/β1/γ2
47.06	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
47.06	Consensus	muscarinic_on_gp	Orthosteric Ligand	m2_on_gp m3_on_gp m4_on_gp m1_on_gp
46.67	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
46.67	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
46.67	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
46.67	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/β1/γ2
46.67	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/β1/γ2
46.67	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
46.67	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/β1/γ2
46.67	Single	8UO3	Constrained Epinephrine	8UO3-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
46.67	Single	8UO4	Constrained Epinephrine	8UO4-β₂-Constrained Epinephrine-GTP; Mg-Gs/β1/γ2
46.67	Single	8YN2	Histamine	8YN2-H₁-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
46.67	Single	8YN4	Histamine	8YN4-H₂-Histamine-chim(NtGi1L-Gs-CtGq)/β1/γ2
46.67	Single	8YN5	Histamine	8YN5-H₃-Histamine-Gi1/β1/γ2
46.67	Single	8YN6	Imetit	8YN6-H₃-Imetit-Gi1/β1/γ2
46.67	Single	8YN7	Immethridine	8YN7-H₃-Immethridine-Go/β1/γ2
46.67	Single	9AS2	DMT	9AS2-5-HT_2A-DMT-chim(NtGi1-Gs-CtGq)/β1/γ2
46.67	Single	9IXJ	Histamine	9IXJ-H₂-Histamine-Gs/β1/γ2
46.67	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
45.83	Single	8XGO	TAK448	8XGO-Kiss1-TAK448-chim(NtGi1-Gq)/β1/γ2
45.45	Consensus	gq_class-a	Orthosteric Ligand	gq_peptide gq_amine gq_nucleotide
45.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
45.00	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
45.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
45.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
45.00	Single	8J19	LY237	8J19-GPR84-LY237-Gi1/β1/γ2
45.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
45.00	Consensus	class-a_on	Orthosteric Ligand	sensory_on alicarboxylic_on amine_on lipid_on nucleotide_on peptide_on protein_on
45.00	Consensus	endothelin_off	Orthosteric Ligand	etb_off
45.00	Consensus	etb_off	Orthosteric Ligand	5X93-ET_B-K-8794 5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500
45.00	Consensus	orexin_on_gp	Orthosteric Ligand	ox2_on_gp
45.00	Consensus	prostanoid_off	Orthosteric Ligand	ep_off dp_off
44.44	Single	5C1M	BU72	5C1M-μ-BU72
44.44	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
44.44	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
44.44	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
44.44	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
44.44	Single	6PS6	Timolol	6PS6-β₂-Timolol
44.44	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
44.44	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/β1/γ2
44.44	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/β1/γ2
44.44	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
44.44	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/β1/γ2
44.44	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/β1/γ2
44.44	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/β1/γ2
44.44	Single	8XYK	VUF10661	8XYK-CXCR3-VUF10661-Go/β1/γ2
44.44	Single	8ZMF	A1L10	8ZMF-5-HT_2C-A1L10
44.44	Consensus	h1_off	Orthosteric Ligand	8X63-H₁-Mepyramine 3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole
44.44	Consensus	m2_off	Orthosteric Ligand	5ZKC-M₂-N-Methyl-Scopolamine 5ZK3-M₂-3-quinuclidinyl-benzilate 5ZKB-M₂-AF-DX 384
43.75	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
43.75	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/β1/γ2
43.75	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/β1/γ2
43.75	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
43.75	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/β1/γ2
43.75	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)
43.75	Single	8IW4	Spermidine	8IW4-TA9-Spermidine-chim(NtGi1-Gs)/β1/γ2
43.75	Single	8IWE	Spermidine	8IWE-TA9-Spermidine
43.75	Single	8YUV	Immepip	8YUV-H₃-Immepip-Gi1/β1/γ2
43.75	Single	9MQJ	Isoquinuclidine	9MQJ-μ-Isoquinuclidine
43.75	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
43.75	Consensus	a1_on_gp	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2
43.75	Consensus	histamine_on	Orthosteric Ligand	h1_on h2_on h3_on h4_on
43.75	Consensus	histamine_on_gp	Orthosteric Ligand	h1_on_gp h2_on_gp h3_on_gp h4_on_gp
43.75	Consensus	sensory_offon	Orthosteric Ligand	sensory_off sensory_on
43.75	Consensus	sensory_offon_gp	Orthosteric Ligand	sensory_on_gp sensory_on
43.48	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
43.48	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
42.86	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
42.86	Single	8GEI	Constrained Epinephrine	8GEI-β₂-Constrained Epinephrine-Gs/β1/γ2
42.86	Single	8IWM	2-Phenylethylamine	8IWM-TA9-2-Phenylethylamine
42.86	Single	9CHU	Noradrenaline	9CHU-β₂-Noradrenaline
42.86	Single	9M0R	Neuropeptide VF	9M0R-NPFF1-Neuropeptide VF-Gi1/β1/γ2
42.86	Consensus	gs_histamine	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
42.86	Consensus	h2_on	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
42.86	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
42.86	Consensus	ox2_on_gp	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2 7SQO-OX₂-TAK-925-Gi1/β1/γ2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
42.31	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_kisspeptin gq_bradykinin gq_bombesin gq_angiotensin
42.11	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
42.11	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
42.11	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
42.11	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
42.11	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
42.11	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/β1/γ2
42.11	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2
42.11	Single	8E0G	BU72	8E0G-μ-BU72
42.11	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
42.11	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/β1/γ2
42.11	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
42.11	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/β1/γ2
42.11	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/β1/γ2
42.11	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/β1/γ2
42.11	Single	8VVF	JDTic	8VVF-κ-JDTic-Gi1/β1/γ2
42.11	Single	8XVL	Zibotentan	8XVL-ET_A-Zibotentan
42.11	Single	9AS9	RS130-180	9AS9-5-HT_2A-RS130-180
42.11	Single	9ASA	RS130-180	9ASA-5-HT_2A-RS130-180-chim(NtGi1-Gs-CtGq)/β1/γ2
42.11	Single	9BJK	Naloxone	9BJK-μ-Naloxone-NAM
42.11	Single	9I54	A1IZV	9I54-D₁-A1IZV-Gs/β1/γ2
42.11	Consensus	a2_on	Orthosteric Ligand	a2b_on
42.11	Consensus	a2_on_gp	Orthosteric Ligand	a2b_on_gp
42.11	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
42.11	Consensus	a2b_on_gp	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2
42.11	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/β1/γ2 8HDO-A_2B-BAY 60-6583-Gs/β1/γ2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/β1/γ2 7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
42.11	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
42.11	Consensus	h4_on_gp	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
42.11	Consensus	m1_on_gp	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
42.11	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
41.67	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
41.67	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/β1/γ2
41.67	Single	8X8L	Cortistatin	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2
41.67	Consensus	angiotensin_on_gp	Orthosteric Ligand	at1_on_gp
41.67	Consensus	at1_on_gp	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
41.67	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/β1/γ2
41.18	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
41.18	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
41.18	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
41.18	Single	6TPG	EMPA	6TPG-OX₂-EMPA
41.18	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
41.18	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/β1/γ2
41.18	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/β1/γ2
41.18	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
41.18	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/β1/γ2
41.18	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
41.18	Single	8PM2	DMCH	8PM2-TA7-DMCH-Gs/β1/γ2
41.18	Single	8YH2	Adenosine	8YH2-A_3A-Adenosine-Gi1/β1/γ2
41.18	Single	8ZMG	Pimavanserin	8ZMG-5-HT_2A-Pimavanserin
41.18	Single	9ARX	Serotonin	9ARX-5-HT_2A-Serotonin
41.18	Single	9LRD	Histamine	9LRD-H₁-Histamine-Gi1/β1/γ2
41.18	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-C-35 5DHH-NOP-SB-612111
40.91	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/β1/γ2
40.91	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/β1/γ2
40.91	Single	8ZBJ	Somatostatin-14	8ZBJ-SST5-Somatostatin-14-Gi1/β1/γ2
40.91	Consensus	class-a_on_gp	Orthosteric Ligand	sensory_on_gp alicarboxylic_on_gp amine_on_gp lipid_on_gp nucleotide_on_gp peptide_on_gp protein_on_gp
40.91	Consensus	gi_opioid	Orthosteric Ligand	8F7R-μ-Endomorphin-Gi1/β1/γ2 8EF5-μ-Fentanyl-Gi1/β1/γ2 7SCG-μ-FH210-Gi1/β1/γ2 7T2H-μ-Lofentanil-Gi1/β1/γ2 7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2 8EF6-μ-Morphine-Gi1/β1/γ2 8F7X-NOP-Nociceptin-Gi1/β1/γ2 8EFB-μ-Oliceridine-Gi1/β1/γ2 7U2L-μ-PubChem 163201242-Gi1/β1/γ2 8EFO-μ-PZM21-Gi1/β1/γ2 8EFL-μ-SR17018-Gi1/β1/γ2 8F7Q-μ-β-Endorphin-Gi1/β1/γ2 7U2K-μ-C6-guano-Gi1/β1/γ2 8EFQ-μ-Damgo-Gi1/β1/γ2 8F7S-δ-Deltorphin-Gi1/β1/γ2 8F7W-κ-Dynorphin-Gi1/β1/γ2
40.91	Consensus	mop_off	Orthosteric Ligand	4DKL-μ-β-Funaltrexamine 8QOT-μ-Nanobody-E 7UL4-μ-Alvimopan
40.00	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
40.00	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
40.00	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
40.00	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/β1/γ2
40.00	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/β1/γ2
40.00	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/β1/γ2
40.00	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
40.00	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/β1/γ2
40.00	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/β1/γ2
40.00	Single	8GGE	Constrained Epinephrine	8GGE-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
40.00	Single	8GH1	Constrained Epinephrine	8GH1-β₂-Constrained Epinephrine
40.00	Single	8ITF	DMCHA	8ITF-TA9-DMCHA-chim(NtGi1-Gs)/β1/γ2
40.00	Single	8IW7	2-Phenylethylamine	8IW7-TA9-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
40.00	Single	8JWY	2-118	8JWY-A_2A-2-118
40.00	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
40.00	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/β1/γ2
40.00	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/β1/γ2
40.00	Single	8W1V	PubChem 171716265	8W1V-β₂-PubChem 171716265
40.00	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/β1/γ2
40.00	Single	8XYI	VUF10661	8XYI-CXCR3-VUF10661
40.00	Single	8YN9	Histamine	8YN9-H₄-Histamine-Gi1/β1/γ2
40.00	Single	8YUU	Histamine	8YUU-H₃-Histamine-Gi1/β1/γ1
40.00	Single	9EBI	Piclidenoson	9EBI-A_3A-Piclidenoson-chim(NtGi1L-Gs-CtGi1)/β1/γ2
40.00	Single	9LRC	Histamine	9LRC-H₄-Histamine
40.00	Single	9LRE	Histamine	9LRE-H₄-Histamine-Gi1/β1/γ2
40.00	Consensus	h2_on_gp	Orthosteric Ligand	8POK-H₂-Histamine-Gs/β1/γ2
40.00	Consensus	h3_on	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
40.00	Consensus	h3_on_gp	Orthosteric Ligand	8YUU-H₃-Histamine-Gi1/β1/γ1
40.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
40.00	Consensus	m4_on_gp	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/β1/γ2 7V6A-M₄-PubChem 9864275-Gi1/β1/γ2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/β1/γ2 7TRK-M₄-Iperoxo-Gi1/β1/γ2
40.00	Consensus	opioid_off	Orthosteric Ligand	mop_off nop_off dop_off kop_off
40.00	Consensus	opsins_on_gp	Orthosteric Ligand	rhodopsin_on_gp opsin1lw_on_gp
40.00	Consensus	orexin_on	Orthosteric Ligand	ox2_on
40.00	Consensus	rhodopsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
40.00	Consensus	sensory_on_gp	Orthosteric Ligand	opsins_on_gp
40.00	Consensus	sst5_on_gp	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
39.29	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
39.29	Consensus	bb2_on_gp	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
39.29	Consensus	bombesin_on	Orthosteric Ligand	bb2_on
39.29	Consensus	bombesin_on_gp	Orthosteric Ligand	bb2_on_gp
39.29	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/β1/γ2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
39.13	Single	6DO1	Angiotensin-like peptide S1I8	6DO1-AT₁-Angiotensin-like peptide S1I8
39.13	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
39.13	Consensus	s1p3_on_gp	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
38.89	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
38.89	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
38.89	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
38.89	Single	4X1H	Nonyl-Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl-β-D-Glucopyranoside-Gt(CT)
38.89	Single	5DHG	C-35	5DHG-NOP-C-35
38.89	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
38.89	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
38.89	Single	5UIG	Cmpd-1	5UIG-A_2A-Cmpd-1
38.89	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
38.89	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
38.89	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/β1/γ2
38.89	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/β1/γ2
38.89	Single	7T2G	Mitragynine Pseudoindoxyl	7T2G-μ-Mitragynine Pseudoindoxyl-Gi1/β1/γ2
38.89	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2
38.89	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
38.89	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/β1/γ1
38.89	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/β1/γ2
38.89	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
38.89	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/β1/γ2
38.89	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
38.89	Single	8T1W	CVN424	8T1W-GPR6-CVN424
38.89	Single	8VVG	GB18	8VVG-κ-GB18-Gi1/β1/γ2
38.89	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
38.89	Single	9D61	JDTic	9D61-κ-JDTic-Gi1/β1/γ2
38.89	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
38.89	Consensus	5ht6_on_gp	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/β1/γ2 8JLZ-5-HT₆-ST1936-Gs/β1/γ2
38.89	Consensus	adenosine_on_gp	Orthosteric Ligand	a1_on_gp a2_on_gp a3_on_gp
38.89	Consensus	alicarboxylic_on_gp	Orthosteric Ligand	succinate_on_gp hca_on_gp
38.89	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
38.89	Consensus	blt1_on_gp	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
38.89	Consensus	blt_on	Orthosteric Ligand	blt1_on
38.89	Consensus	blt_on_gp	Orthosteric Ligand	blt1_on_gp
38.89	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
38.89	Consensus	gi_alicarboxylic	Orthosteric Ligand	gi_hca gi_succinate
38.89	Consensus	gi_histamine	Orthosteric Ligand	8JXX-H₄-Clobenpropit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8YUU-H₃-Histamine-Gi1/β1/γ1 8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2
38.89	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/β1/γ2
38.89	Consensus	histamine_off	Orthosteric Ligand	h1_off
38.89	Consensus	leukotriene_on	Orthosteric Ligand	blt_on
38.89	Consensus	leukotriene_on_gp	Orthosteric Ligand	blt_on_gp
38.89	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
38.46	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
38.46	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/β1/γ2
38.46	Consensus	gi_peptide	Orthosteric Ligand	gi_cck gi_apelin gi_compl-pept gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_npy gi_neurotensin gi_opioid gi_orexin gi_relaxin gi_somatostatin
38.10	Single	5X93	K-8794	5X93-ET_B-K-8794
38.10	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/β1/γ2
38.10	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/β1/γ2
38.10	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/β1/γ2
38.10	Single	8ZWG	JR14a	8ZWG-C3a_B-JR14a-Gi1/β1/γ2
38.10	Single	9CGJ	C6-Quino	9CGJ-δ-C6-Quino-Gi1/β1/γ2
38.10	Consensus	gi_s1p	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7EW3-S1P₃-S1P-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EW1-S1P₅-Siponimod-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
38.10	Consensus	nucleotide_on_gp	Orthosteric Ligand	adenosine_on_gp p2y_on_gp
37.50	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
37.50	Single	2G87	All-trans-Retinal	2G87-Rhodopsin-All-trans-Retinal
37.50	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
37.50	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
37.50	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
37.50	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/β1/γ2
37.50	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
37.50	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/β1/γ2
37.50	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/β1/γ2
37.50	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
37.50	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/β1/γ2
37.50	Single	8XGU	TAK448	8XGU-Kiss1-TAK448-Gi1/β1/γ2
37.50	Single	8XIQ	L796778	8XIQ-SST3-L796778-chim(NtGi1-Gs-CtGi1)/β1/γ2
37.50	Single	8ZSV	RO5263397	8ZSV-TA1-RO5263397-chim(NtGi1-Gs)/β1/γ2
37.50	Single	9AS7	Psilocin	9AS7-5-HT_2A-Psilocin
37.50	Consensus	5ht4_on	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
37.50	Consensus	5ht4_on_gp	Orthosteric Ligand	7XTA-5-HT₄-Serotonin-Gi1/β1/γ2
37.50	Consensus	gi_somatostatin	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
37.50	Consensus	peptide_offon	Orthosteric Ligand	peptide_off peptide_on
37.50	Consensus	somatostatin_on	Orthosteric Ligand	sst2_on sst4_on sst5_on
37.50	Consensus	somatostatin_on_gp	Orthosteric Ligand	sst2_on_gp sst4_on_gp sst5_on_gp
37.04	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2
37.04	Single	9K26	PrRP31	9K26-PrRP-PrRP31-Gi1/β1/γ2
37.04	Single	9KDF	RES-701-3	9KDF-ET_B-RES-701-3
37.04	Consensus	peptide_on	Orthosteric Ligand	cck_on angiotensin_on apelin_on bombesin_on bradykinin_on compl-peptide_on endothelin_on formylpeptide_on galanin_on ghrelin_on kisspeptin_on melanocortin_on motilin_on neuromedin-u_on npy_on neurotensin_on opioid_on orexin_on relaxin_on somatostatin_on tachykinin_on trh_on vasop-oxy_on
37.04	Consensus	peptide_on_gp	Orthosteric Ligand	cck_on_gp angiotensin_on_gp apelin_on_gp bombesin_on_gp bradykinin_on_gp compl-peptide_on_gp endothelin_on_gp formylpeptide_on_gp galanin_on_gp ghrelin_on_gp kisspeptin_on_gp melanocortin_on_gp motilin_on_gp neuromedin-u_on_gp npy_on_gp neurotensin_on_gp opioid_on_gp orexin_on_gp relaxin_on_gp somatostatin_on_gp tachykinin_on_gp trh_on_gp vasop-oxy_on_gp
36.84	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
36.84	Single	5WQC	EMPA	5WQC-OX₂-EMPA
36.84	Single	5ZK3	3-quinuclidinyl-benzilate	5ZK3-M₂-3-quinuclidinyl-benzilate
36.84	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
36.84	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
36.84	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/β1/γ2
36.84	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/β1/γ2
36.84	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-MIPS521-Gi2/β1/γ2
36.84	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/β1/γ2
36.84	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/β1/γ2
36.84	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/β1/γ2
36.84	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/β1/γ2
36.84	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/β1/γ2
36.84	Single	8J18	(3R)-3-Hydroxydodecanoic acid	8J18-GPR84-(3R)-3-Hydroxydodecanoic acid-Gi1/β1/γ2
36.84	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/β1/γ2
36.84	Single	8JXS	PF-6142	8JXS-D₁-PF-6142
36.84	Single	8TH4	Losartan	8TH4-AT₁-Losartan-AT118-L Nanobody
36.84	Single	8YH0	NECA	8YH0-A_3A-NECA-Gi1/β1/γ2
36.84	Single	8YIC	SAR247799	8YIC-S1P₁-SAR247799-Gi1/β1/γ2
36.84	Single	9EAH	Olmesartan	9EAH-AT₁-Olmesartan-Nanobody AT209
36.84	Single	9EE8	Adenosine	9EE8-A_2A-Adenosine-Gs/β1/γ2
36.84	Single	9EHS	LUF7602	9EHS-A_3A-LUF7602
36.84	Single	9I52	A1IZU	9I52-D₁-A1IZU-Gs/β1/γ2
36.84	Consensus	a3_on_gp	Orthosteric Ligand	a3a_on_gp
36.84	Consensus	a3a_on	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
36.84	Consensus	a3a_on_gp	Orthosteric Ligand	8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
36.84	Consensus	dp2_off	Orthosteric Ligand	6D26-DP₂-Fevipiprant
36.84	Consensus	dp_off	Orthosteric Ligand	dp2_off
36.84	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
36.84	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/β1/γ2
36.36	Single	6PT3	DPI-287	6PT3-δ-DPI-287
36.36	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
36.36	Single	7XY6	BAY 60-6583	7XY6-A_2B-BAY 60-6583-chim(NtGi1-Gs)/β1/γ2
36.36	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/β1/γ2
36.36	Single	8Y72	Peptide	8Y72-μ-Peptide-BMS-986122-Gi1/β1/γ2
36.36	Single	9CGK	C5-Quino	9CGK-δ-C5-Quino-Gi1/β1/γ2
36.36	Consensus	s1p_on	Orthosteric Ligand	s1p1_on s1p3_on s1p5_on
36.36	Consensus	s1p_on_gp	Orthosteric Ligand	s1p1_on_gp s1p3_on_gp s1p5_on_gp
36.36	Consensus	sst2_on	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
36.36	Consensus	sst2_on_gp	Orthosteric Ligand	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2 7WIG-SST2-L-054,264-Gi1/β1/γ2 7YAE-SST2-Octreotide-Gi1/β1/γ2 7YAC-SST2-Paltusotine-Gi1/β1/γ2
36.00	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
36.00	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/β1/γ2
36.00	Single	8ZBI	Somatostatin-14	8ZBI-SST3-Somatostatin-14-Gi1/β1/γ2
36.00	Single	9BKK	Cholecystokinin-8	9BKK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
36.00	Consensus	cxcr3_on_gp	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
36.00	Consensus	gi_class-a	Orthosteric Ligand	gi_peptide gi_sensory gi_alicarboxylic gi_amine gi_lipid gi_nucleotide gi_protein
36.00	Consensus	peptide_offon_gp	Orthosteric Ligand	peptide_on_gp peptide_off
35.29	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
35.29	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
35.29	Single	6AKX	A4R	6AKX-CCR5-A4R
35.29	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
35.29	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
35.29	Single	6OYA	All-trans-Retinal	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
35.29	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
35.29	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/β1/γ2
35.29	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
35.29	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2
35.29	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
35.29	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
35.29	Single	7T96	Acetylcholine	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
35.29	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/β1/γ2
35.29	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/β1/γ2
35.29	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/β1/γ2
35.29	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/β1/γ2
35.29	Single	8WOG	Succinic acid	8WOG-Succinate-Succinic acid-Gi1/β1/γ2
35.29	Single	8YKX	Maleic acid	8YKX-Succinate-Maleic acid-Gi1/β1/γ1
35.29	Single	8YNA	Immepip	8YNA-H₄-Immepip-Gi1/β1/γ2
35.29	Single	9EBH	Adenosine	9EBH-A_3A-Adenosine-Gi1/β1/γ2
35.29	Single	9LRB	Histamine	9LRB-H₁-Histamine-Gs/β1/γ2
35.29	Consensus	5ht2_on_gp	Orthosteric Ligand	5ht2b_on_gp
35.29	Consensus	5ht2b_on_gp	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
35.29	Consensus	gi_succinate	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
35.29	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
35.29	Consensus	m2_on_gp	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/β1/γ2
35.29	Consensus	rhodopsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
35.29	Consensus	rhodopsin_on_gp	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
35.29	Consensus	succinate_on	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
35.29	Consensus	succinate_on_gp	Orthosteric Ligand	8YKW-Succinate-Succinic acid-Gi1/β1/γ1 8YKX-Succinate-Maleic acid-Gi1/β1/γ1
35.00	Single	3UON	3-quinuclidinyl-benzilate	3UON-M₂-3-quinuclidinyl-benzilate
35.00	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
35.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
35.00	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
35.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/β1/γ2
35.00	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
35.00	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/β1/γ2
35.00	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/β1/γ2
35.00	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/β1/γ2
35.00	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/β1/γ2
35.00	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/β1/γ2
35.00	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/β1/γ2
35.00	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/β1/γ2
35.00	Single	8T1V	PubChem 118310209	8T1V-GPR6-PubChem 118310209-Na
35.00	Single	8UGW	PubChem 3086599	8UGW-A_2A-PubChem 3086599
35.00	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
35.00	Consensus	s1p5_on_gp	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/β1/γ2
34.78	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
34.78	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/β1/γ2
34.78	Consensus	chemerin_on_gp	Orthosteric Ligand	cml1_on_gp
34.78	Consensus	cml1_on	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
34.78	Consensus	gi_chemerin	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
34.78	Consensus	sst5_on	Orthosteric Ligand	8X8L-SST5-Cortistatin-chim(NtGi1-Gs-CtGi1)/β1/γ2 8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
34.62	Single	8XQE	Apelin-13	8XQE-Apelin-Apelin-13-Gi1/β1/γ2
34.62	Single	8ZPS	PrRP20	8ZPS-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
34.62	Consensus	cml1_on_gp	Orthosteric Ligand	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
34.62	Consensus	opioid_on	Orthosteric Ligand	mop_on nop_on dop_on kop_on
33.33	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
33.33	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
33.33	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
33.33	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
33.33	Single	3REY	XAC	3REY-A_2A-XAC
33.33	Single	3UZC	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	3UZC-A_2A-4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
33.33	Single	4DKL	Beta-Funaltrexamine	4DKL-μ-β-Funaltrexamine
33.33	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
33.33	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
33.33	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
33.33	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
33.33	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
33.33	Single	6IQL	L745870	6IQL-D₄-L745870
33.33	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
33.33	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
33.33	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
33.33	Single	6VI4	JDTic	6VI4-κ-JDTic
33.33	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
33.33	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
33.33	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/β1/γ2
33.33	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
33.33	Single	7F61	PF-03654746	7F61-H₃-PF-03654746
33.33	Single	7MTB	All-trans-Retinal	7MTB-Rhodopsin-All-trans-Retinal-GRK1
33.33	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/β1/γ2
33.33	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/β1/γ2
33.33	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/β1/γ2
33.33	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/β1/γ2
33.33	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
33.33	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
33.33	Single	8GUR	CP55,940	8GUR-CB₂-CP55,940-Gi1/β1/γ2
33.33	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/β1/γ2
33.33	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/β1/γ2
33.33	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/β1/γ2
33.33	Single	8JEI	3-nitro-4-(propylamino)benzoic acid	8JEI-HCAR3-3-nitro-4-(propylamino)benzoic acid-Gi1/β1/γ2
33.33	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/β1/γ2
33.33	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/β1/γ2
33.33	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
33.33	Single	8RLN	LUF5834	8RLN-A_2A-LUF5834
33.33	Single	8RWI	StilSwitch2	8RWI-A_2A-StilSwitch2-Na
33.33	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/β1/γ2
33.33	Single	8WC5	Tetramethylammonium Ion	8WC5-TA1-Tetramethylammonium Ion-chim(NtGi1-Gs)/β1/γ2
33.33	Single	8Y45	ADL5859	8Y45-δ-ADL5859-Gi2/β1/γ2
33.33	Single	9EE9	Adenosine	9EE9-A_2A-Adenosine-Gs/β1/γ2
33.33	Single	9GYO	P395	9GYO-GPBA-P395-chim(NtGi1-Gs)/β1/γ2
33.33	Single	9IK8	SST analogue	9IK8-SST1-SST analogue-Gi1/β1/γ2
33.33	Single	9IQV	Muscarinic toxin 3	9IQV-Alpha1A-Muscarinic toxin 3
33.33	Single	9JH3	CMF-019	9JH3-Apelin-CMF-019-Gi1/β1/γ2
33.33	Single	9JMD	Azithromycin	9JMD-Motilin-Azithromycin-chim(Gs-CtGq)/β1/γ2
33.33	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6A93-5-HT_2A-Risperidone 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 8JT8-5-HT_2A-(R)-IHCH-7179
33.33	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on a3_on
33.33	Consensus	cannabinoid_off	Orthosteric Ligand	cb2_off cb1_off
33.33	Consensus	cckb_on	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
33.33	Consensus	gi_adenosine	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/β1/γ2 8X17-A_3A-Namodenoson-Gi1/β1/γ2 8X16-A_3A-Piclidenoson-Gi1/β1/γ2
33.33	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
33.33	Consensus	hca_on	Orthosteric Ligand	hca2_on
33.33	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
33.33	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
33.33	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
33.33	Consensus	npy4_on_gp	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
33.33	Consensus	opioid_on_gp	Orthosteric Ligand	mop_on_gp nop_on_gp dop_on_gp kop_on_gp
33.33	Consensus	opsins_off	Orthosteric Ligand	rhodopsin_off
33.33	Consensus	opsins_on	Orthosteric Ligand	rhodopsin_on opsin1lw_on
33.33	Consensus	s1p1_on	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
33.33	Consensus	s1p1_on_gp	Orthosteric Ligand	7VIE-S1P₁-S1P-Gi1/β1/γ2 7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2 7VIG-S1P₁-CBP-307-Gi1/β1/γ2 7EVY-S1P₁-Siponimod-Gi1/β1/γ2 7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2 7EW0-S1P₁-Ozanimod-Gi1/β1/γ2 7EW7-S1P₁-SEW2871-Gi1/β1/γ2
33.33	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/β1/γ2 7EW4-S1P₃-CYM5541-Gi1/β1/γ2 7EW2-S1P₃-Fingolimod-Gi1/β1/γ2
33.33	Consensus	sensory_off	Orthosteric Ligand	opsins_off
33.33	Consensus	sensory_on	Orthosteric Ligand	opsins_on
33.33	Consensus	sst4_on	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
33.33	Consensus	sst4_on_gp	Orthosteric Ligand	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2 7XMT-SST4-J-2156-Gi1/β1/γ2
32.14	Single	8FEG	(DNCP)-Beta-Naloxamine	8FEG-κ-(DNCP)-β-Naloxamine-Gi1/β1/γ2
32.14	Single	8WWL	MCH	8WWL-MCH1-MCH-Gi1/β1/γ2
32.14	Single	8ZH8	QRF-Amide	8ZH8-QRFP-QRF-Amide-Gq/β1/γ1
32.00	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/β1/γ2
32.00	Single	8XIR	Pasireotide	8XIR-SST3-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
32.00	Single	9B54	A1AIW	9B54-CB₁-A1AIW-Gi1/β1/γ2
32.00	Single	9U4W	Gonadoliberin-1	9U4W-GnRH₁-Gonadoliberin-1-chim(NtGi1L-Gs-CtGq)/β1/γ2
32.00	Consensus	cckb_on_gp	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7F8V-CCK_B-Gastrin-17-Gi2/β1/γ2
32.00	Consensus	gs_class-a	Orthosteric Ligand	gs_peptide gs_nucleotide gs_amine
31.82	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/β1/γ2
31.82	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/β1/γ2
31.82	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/β1/γ2
31.82	Single	7EZC	UKA	7EZC-A_2A-UKA
31.82	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/β1/γ2
31.82	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/β1/γ2
31.82	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/β1/γ2
31.82	Single	8I95	EP54	8I95-C3a_B-EP54-Go/β1/γ2
31.82	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-chim(NtGi2L-Gs-CtGq)/β1/γ2
31.82	Single	8XIO	L797591	8XIO-SST1-L797591-chim(NtGi1-Gs-CtGi1)/β1/γ2
31.82	Single	9EAI	Losartan	9EAI-AT₁-Losartan-Nanobody AT209
31.82	Single	9M54	Neuropeptide VF	9M54-NPFF2-Neuropeptide VF-Gi1/β1/γ2
31.82	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
31.82	Consensus	cck_on_gp	Orthosteric Ligand	ccka_on_gp cckb_on_gp
31.82	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
31.82	Consensus	kop_on_gp	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/β1/γ2 8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2 8DZP-κ-momSalB-Gi1/β1/γ2
31.58	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl β-D-Glucopyranoside-Gt(CT)
31.58	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
31.58	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
31.58	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
31.58	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
31.58	Single	6D27	CAY10471	6D27-DP₂-CAY10471
31.58	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
31.58	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/β1/γ2
31.58	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/β1/γ2
31.58	Single	7VIF	S-FTY720-P	7VIF-S1P₁-S-FTY720-P-Gi1/β1/γ2
31.58	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
31.58	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
31.58	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/β1/γ2
31.58	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/β1/γ2
31.58	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/β1/γ2
31.58	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
31.58	Single	8JD0	NAM563	8JD0-mGlu2; mGlu3-Glutamate-NAM563
31.58	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/β1/γ2
31.58	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/β1/γ2
31.58	Single	8RWX	StilSwitch3	8RWX-A_2A-StilSwitch3-Na
31.58	Single	8X17	Namodenoson	8X17-A_3A-Namodenoson-Gi1/β1/γ2
31.58	Single	8YH5	Riboprine	8YH5-A_3A-Riboprine-Gi1/β1/γ2
31.58	Single	9BQJ	RO76	9BQJ-μ-RO76-Gi1/β1/γ2
31.58	Single	9EPP	11,20-Ethanoretinal	9EPP-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
31.58	Single	9KFJ	PubChem 138319674	9KFJ-RXFP3-PubChem 138319674-Gi2/β1/γ2
31.58	Consensus	a3_on	Orthosteric Ligand	a3a_on
31.58	Consensus	gi_hca	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
31.58	Consensus	hca2_on	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2
31.58	Consensus	hca2_on_gp	Orthosteric Ligand	8J6R-HCA₂-MK6892-Gi1/β1/γ2 8IHI-HCA₂-Acifran-Gi1/β1/γ2 8IHH-HCA₂-LUF6283-Gi1/β1/γ2 8I7V-HCA₂-Acipimox-Gi1/β1/γ2 8JIM-HCA₂-MMF-Gi1/β1/γ2 8I7W-HCA₂-GSK256073-Gi1/β1/γ2
31.58	Consensus	hca_on_gp	Orthosteric Ligand	hca2_on_gp
31.25	Single	3PQR	All-trans-Retinal	3PQR-Rhodopsin-All-trans-Retinal-Gt(CT)
31.25	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
31.25	Single	8GGF	Constrained Epinephrine	8GGF-β₂-Constrained Epinephrine-GTP-Gs/β1/γ2
31.25	Single	8J6Q	Beta-Hydroxybutyrate	8J6Q-HCA₂-β-Hydroxybutyrate-Compound 9n-Gi1/β1/γ2
31.25	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/β1/γ2
31.25	Single	8Y63	C20:0 Ceramide	8Y63-FPR2-ALX-C20:0 Ceramide-Gi1/β1/γ2
31.25	Consensus	5ht2_on	Orthosteric Ligand	5ht2b_on
31.25	Consensus	5ht2b_on	Orthosteric Ligand	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/β1/γ2
31.03	Single	8Y52	BA1	8Y52-BB₃-BA1-chim(NtGi1-Gs-CtGq)/β1/γ2
30.77	Single	8WST	Pro-MCH	8WST-MCH2-Pro-MCH-chim(NtGi1L-Gs-CtGq)/β1/γ2
30.77	Single	8XWQ	Endothelin-1	8XWQ-ET_B-Endothelin-1-Gi1/β1/γ2
30.77	Consensus	fpr2-alx_on_gp	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
30.77	Consensus	protein_on	Orthosteric Ligand	chemokine_on chemerin_on
30.43	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
30.43	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
30.43	Single	7T11	Octreotide	7T11-SST2-Octreotide-Gi3/β1/γ2
30.43	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/β1/γ2
30.43	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/β1/γ2
30.43	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2
30.43	Single	9IPV	JR14a	9IPV-C3a_B-JR14a-Gi1/β1/γ2
30.43	Single	9IZA	SCH900271	9IZA-HCA₂-SCH900271-Gi1/β1/γ2
30.43	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
30.43	Consensus	cxcr3_on	Orthosteric Ligand	8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2
30.43	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
30.43	Consensus	formylpeptide_on	Orthosteric Ligand	fpr2-alx_on fpr1-alx_on
30.00	Single	4WW3	All-trans-Retinal	4WW3-Rhodopsin-All-trans-Retinal
30.00	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
30.00	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
30.00	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
30.00	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/β1/γ1
30.00	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
30.00	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
30.00	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
30.00	Single	7BB7	AVP	7BB7-V₂-AVP-Gs/β1/γ2
30.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/β1/γ2
30.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/β1/γ2
30.00	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
30.00	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
30.00	Single	8UUJ	FCH-2296413	8UUJ-HCA₂-FCH-2296413-Gi1/β1/γ2
30.00	Single	8ZJE	TAK-448	8ZJE-Kiss1-TAK-448-chim(NtGi1-Gq)/β1/γ1
30.00	Single	8ZPT	PrRP20	8ZPT-PrRP-PrRP20-chim(NtGi1-Gs-CtGq)/β1/γ2
30.00	Single	8ZRK	GSK-1292263	8ZRK-GPR119-GSK-1292263-Gs/β1/γ2
30.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
30.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
30.00	Single	9CIB	FCH-2296413	9CIB-HCA₂-FCH-2296413
30.00	Single	9HAP	Tolvaptan	9HAP-V₂-Tolvaptan
30.00	Consensus	cb2_on	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
30.00	Consensus	cb2_on_gp	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2
30.00	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
30.00	Consensus	fpr1-alx_on_gp	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2
30.00	Consensus	gi_npy	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1 7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2 7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
30.00	Consensus	npy_on	Orthosteric Ligand	npy1_on npy2_on npy4_on
30.00	Consensus	npy_on_gp	Orthosteric Ligand	npy1_on_gp npy2_on_gp npy4_on_gp
30.00	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on p2y_on
29.63	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/β1/γ2
29.63	Single	8WWK	MCH	8WWK-MCH1-MCH-Gi1/β1/γ2
29.63	Single	8WWM	MCH	8WWM-MCH1-MCH-Gi1/β1/γ2
29.63	Single	9JFY	hNPSF	9JFY-NPFF2-hNPSF-Gi1/β1/γ2
29.41	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
29.41	Single	3AYM	All-trans-Retinal	3AYM-Rhodopsin-All-trans-Retinal
29.41	Single	6HLL	CP99994	6HLL-NK₁-CP99994
29.41	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
29.41	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
29.41	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/β1/γ2
29.41	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/β1/γ2
29.41	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
29.41	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/β1/γ2
29.41	Single	8JPN	Cis-Epoxysuccinic acid	8JPN-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ1
29.41	Single	8WP1	Cis-Epoxysuccinic acid	8WP1-Succinate-Cis-Epoxysuccinic acid-Gi1/β1/γ2
29.41	Single	8YH3	N-methyladenosine	8YH3-A_3A-N-methyladenosine-Gi1/β1/γ2
29.41	Single	8YKW	Succinic acid	8YKW-Succinate-Succinic acid-Gi1/β1/γ1
29.41	Consensus	h4_on	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/β1/γ2 8HOC-H₄-Imetit-Gi1/β1/γ2 8JXV-H₄-Clozapine-Gi1/β1/γ2 8JXW-H₄-VUF6884-Gi1/β1/γ2 8JXX-H₄-Clobenpropit-Gi1/β1/γ2
29.17	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/β1/γ2
29.17	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/β1/γ2
29.17	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/β1/γ2
29.17	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/β1/γ2
29.17	Single	8G59	TUG-891	8G59-FFA4-TUG-891-chim(Gi1-CtGq)/β1/γ2
29.17	Single	8GHV	AMG315	8GHV-CB₁-AMG315-Gi1/β1/γ2
29.17	Consensus	gi_nucleotide	Orthosteric Ligand	gi_adenosine gi_p2y
29.17	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
29.17	Consensus	lpl_on_gp	Orthosteric Ligand	s1p_on_gp lpa_on_gp
29.17	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
29.17	Consensus	nop_on_gp	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/β1/γ2
28.57	Single	4DJH	JDTic	4DJH-κ-JDTic
28.57	Single	5XR8	AM841	5XR8-CB₁-AM841
28.57	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/β1/γ2
28.57	Single	6E59	L-760735	6E59-NK₁-L-760735
28.57	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/β1/γ2
28.57	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/β1/γ2
28.57	Single	7EW7	SEW2871	7EW7-S1P₁-SEW2871-Gi1/β1/γ2
28.57	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
28.57	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
28.57	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/β1/γ2
28.57	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2
28.57	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/β1/γ2
28.57	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/β1/γ2
28.57	Single	8GEJ	Constrained Epinephrine	8GEJ-β₂-Constrained Epinephrine-Gs/β1/γ2
28.57	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4-9-Hydroxystearic acid-Gi1/β1/γ2
28.57	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/β1/γ2
28.57	Single	8VVE	norBNI	8VVE-κ-norBNI-Gi1/β1/γ2
28.57	Single	8WU1	PubChem 119025665	8WU1-CB₁-PubChem 119025665-Arrestin2
28.57	Single	8X16	Piclidenoson	8X16-A_3A-Piclidenoson-Gi1/β1/γ2
28.57	Single	8XVE	BQ3020	8XVE-ET_B-BQ3020-chim(Gs-CtGq)/β1/γ2
28.57	Single	8XZI	CMF-019	8XZI-Apelin-CMF-019-Gi1/β1/γ2
28.57	Single	8Y73	Peptide	8Y73-μ-Peptide-MPAM-15-Gi1/β1/γ2
28.57	Single	8YH6	Namodenoson	8YH6-A_3A-Namodenoson-Gi1/β1/γ2
28.57	Single	8ZR5	Firuglipel	8ZR5-GPR119-Firuglipel-Gs/β1/γ2
28.57	Single	8ZWF	JR14a	8ZWF-C3a_B-JR14a
28.57	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
28.57	Single	9KFK	Relaxin-3	9KFK-RXFP4-Relaxin-3-Gi2/β1/γ2
28.57	Single	9UY3	Anamorelin	9UY3-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
28.57	Consensus	class-a_off	Orthosteric Ligand	sensory_off alicarboxylic_off amine_off lipid_off nucleotide_off peptide_off protein_off
28.57	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUR-CB₂-CP55,940-Gi1/β1/γ2 8GUS-CB₂-HU-308-Gi1/β1/γ2 8GUT-CB₂-LEI-102-Gi1/β1/γ2 8GUQ-CB₂-Olorinab-Gi1/β1/γ2 6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2 6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2 6KPG-CB₁-AM841-Gi1/β1/γ2
28.57	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
28.57	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
28.57	Consensus	protein_on_gp	Orthosteric Ligand	chemokine_on_gp chemerin_on_gp
28.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/β1/γ2
28.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
28.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/β1/γ2
28.00	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/β1/γ2
28.00	Single	8WSS	Pro-MCH	8WSS-MCH1-Pro-MCH-Gi1/β1/γ1
28.00	Single	9E82	SDF-1-beta	9E82-ACKR3-SDF-1-β-Arrestin2
28.00	Single	9KFI	Relaxin-3	9KFI-RXFP3-Relaxin-3-Gi2/β1/γ2
28.00	Consensus	dop_on_gp	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/β1/γ2
28.00	Consensus	formylpeptide_on_gp	Orthosteric Ligand	fpr2-alx_on_gp fpr1-alx_on_gp
28.00	Consensus	ghrelin_on	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
28.00	Consensus	ghrelin_on_gp	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
28.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2 7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
27.78	Single	2X72	All-trans-Retinal	2X72-Rhodopsin-All-trans-Retinal-Gt(CT)
27.78	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
27.78	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
27.78	Single	3VGA	ZM-241385	3VGA-A_2A-ZM-241385-Antibody
27.78	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
27.78	Single	5WS3	EMPA	5WS3-OX₂-EMPA
27.78	Single	6B73	MP1104	6B73-κ-MP1104
27.78	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/β1/γ2
27.78	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
27.78	Single	6NWE	Octyl-Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
27.78	Single	7TUZ	7-alpha,25-dihydroxycholesterol	7TUZ-GPR183-7-α,25-dihydroxycholesterol-Gi1/β1/γ2
27.78	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/β1/γ2
27.78	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
27.78	Single	8A6C	All-trans-Retinal	8A6C-Rhodopsin-All-trans-Retinal
27.78	Single	8A6D	All-trans-Retinal	8A6D-Rhodopsin-All-trans-Retinal
27.78	Single	8A6E	All-trans-Retinal	8A6E-Rhodopsin-All-trans-Retinal
27.78	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
27.78	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/β1/γ2
27.78	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/β1/γ2
27.78	Single	8JPP	Succinic acid	8JPP-Succinate-Succinic acid-chim(Gs-CtGq)/β1/γ1
27.78	Single	8RW0	Istradefylline	8RW0-A_2A-Istradefylline-Na
27.78	Single	8Y0H	VUF11418	8Y0H-CXCR3-VUF11418
27.78	Single	8Y0N	VUF11418	8Y0N-CXCR3-VUF11418-Go/β1/γ2
27.78	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
27.78	Single	9EEA	Adenosine	9EEA-A_2A-Adenosine-Gs/β1/γ2
27.78	Single	9H2X	A1IR1	9H2X-A_2A-A1IR1-Na
27.78	Consensus	angiotensin_off	Orthosteric Ligand	at1_off
27.78	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
27.78	Consensus	ox1_off	Orthosteric Ligand	6TP6-OX₁-Filorexant 6TP4-OX₁-ACT-462206 6V9S-OX₁-GTPL11403 6TOT-OX₁-Lemborexant 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant 6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na
27.78	Consensus	ox2_off	Orthosteric Ligand	5WQC-OX₂-EMPA 6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant 6TPJ-OX₂-Suvorexant
27.59	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/β1/γ2
27.59	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/β1/γ2
27.59	Single	7YOO	Neuropeptide-Y	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
27.59	Single	8XWP	Endothelin-1	8XWP-ET_B-Endothelin-1-Gi1/β1/γ2
27.59	Single	8ZJG	Chemerin	8ZJG-CML1-Chemerin-Gi1/β1/γ2
27.59	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
27.59	Consensus	npy2_on_gp	Orthosteric Ligand	7YOO-Y₂-Neuropeptide-Y-Gi1/β1/γ2
27.27	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
27.27	Single	7EPE	NAM563	7EPE-mGlu2; mGlu2-NAM563
27.27	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/β1/γ2
27.27	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
27.27	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
27.27	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
27.27	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/β1/γ2
27.27	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/β1/γ2
27.27	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/β1/γ2
27.27	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
27.27	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/β1/γ2
27.27	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/β1/γ2
27.27	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/β1/γ2
27.27	Single	8JJP	Chemerin	8JJP-CML2-Chemerin-Gi1/β1/γ2
27.27	Single	8T3Q	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3Q-FFA4-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
27.27	Single	8VHF	MBX-2982	8VHF-GPR119-MBX-2982-Gs/β1/γ2
27.27	Single	8X8N	Octreotide	8X8N-SST5-Octreotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
27.27	Single	9DGI	Z8526711350	9DGI-CB₁-Z8526711350
27.27	Single	9L3W	Retinoic acid receptor responder protein 2	9L3W-CML1-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
27.27	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
27.27	Consensus	cannabinoid_on	Orthosteric Ligand	cb2_on cb1_on
27.27	Consensus	cannabinoid_on_gp	Orthosteric Ligand	cb2_on_gp cb1_on_gp
27.27	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_ffa gi_leukotriene gi_lpa gi_s1p
27.27	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
27.27	Consensus	trh_on_gp	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/β1/γ2
26.92	Single	9K27	PrRP31	9K27-PrRP-PrRP31-chim(NtGi1-Gq)/β1/γ2
26.92	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
26.67	Single	3PXO	All-trans-Retinal	3PXO-Rhodopsin-All-trans-Retinal
26.67	Single	5DYS	All-trans-Retinal	5DYS-Rhodopsin-All-trans-Retinal
26.67	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
26.67	Single	8WWN	MCH	8WWN-MCH1-MCH-Gi1/β1/γ2
26.67	Consensus	bk2_on	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
26.67	Consensus	bk2_on_gp	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
26.67	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on
26.67	Consensus	bradykinin_on_gp	Orthosteric Ligand	bk2_on_gp
26.67	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/β1/γ2 7F6I-BK₂-Kallidin-Gq/β1/γ2
26.32	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
26.32	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
26.32	Single	5K2B	ZM-241385	5K2B-A_2A-ZM-241385-Na
26.32	Single	5NLX	ZM-241385	5NLX-A_2A-ZM-241385-Na
26.32	Single	5TE3	Octyl-Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl-β-D-Glucopyranoside
26.32	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
26.32	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
26.32	Single	6ZDV	Chromone 5d	6ZDV-A_2A-Chromone 5d-Na
26.32	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
26.32	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
26.32	Single	7T32	ZM-241385	7T32-A_2A-ZM-241385
26.32	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
26.32	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/β1/γ2
26.32	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
26.32	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
26.32	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/β1/γ2
26.32	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
26.32	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/β1/γ2
26.32	Single	8K9K	Damgo	8K9K-μ-Damgo-Gi3/β1/γ1
26.32	Single	8RWC	StilSwitch2	8RWC-A_2A-StilSwitch2-Na
26.32	Single	8RWD	StilSwitch3	8RWD-A_2A-StilSwitch3-Na
26.32	Single	8Y01	Retinal	8Y01-Opsin1MW-Retinal-Gi1/β1/γ2
26.32	Single	8Y53	MK5046	8Y53-BB₃-MK5046-chim(NtGi1-Gs-CtGq)/β1/γ2
26.32	Single	8Y62	C16:0 Ceramide	8Y62-FPR2-ALX-C16:0 Ceramide-Gi1/β1/γ2
26.32	Single	8YKV	PubChem 137553168	8YKV-Succinate-PubChem 137553168-Gi1/β1/γ2
26.32	Single	8ZPM	AMD070	8ZPM-CXCR4-AMD070
26.32	Single	9EPQ	11,20-Ethanoretinal	9EPQ-Rhodopsin-11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ2
26.32	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
26.32	Consensus	p2y1_on_gp	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
26.09	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
26.09	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2
26.09	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/β1/γ2
26.09	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/β1/γ2
26.09	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/β1/γ2
26.09	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/β1/γ2
26.09	Single	8GAG	PubChem 170838490	8GAG-CB₁-PubChem 170838490-Gi1/β1/γ2
26.09	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
26.09	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/β1/γ2
26.09	Single	8XVJ	Macitentan	8XVJ-ET_A-Macitentan
26.09	Single	9GE3	Lysophosphatidylinositol	9GE3-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
26.09	Consensus	c3a_on_gp	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
26.09	Consensus	cb1_on_gp	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
26.09	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
26.09	Consensus	ccka_on_gp	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/β1/γ2
26.09	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
25.93	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
25.93	Single	7DW9	AVP	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
25.93	Single	7KH0	AVP	7KH0-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
25.93	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/β1/γ2
25.93	Single	7YON	Peptide-YY(3-36)	7YON-Y₂-Peptide-YY(3-36)-Gi1/β1/γ2
25.93	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/β1/γ2
25.93	Consensus	gi_formylpeptide	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-β42-Gi2/β1/γ2 7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2 7VFX-FPR1-ALX-fMLF-Gi1/β1/γ2 7T6V-FPR2-ALX-fMLFII-Gi1/β1/γ2 7WVX-FPR2-ALX-Humanin-Gi2/β1/γ2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/β1/γ2 6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
25.93	Consensus	gs_vasop-oxy	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
25.93	Consensus	p2y_on_gp	Orthosteric Ligand	p2y1_on_gp p2y10_on_gp p2y12_on_gp
25.93	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
25.93	Consensus	v2_on_gp	Orthosteric Ligand	7DW9-V₂-AVP-chim(NtGi1-Gs)/β1/γ2
25.93	Consensus	vasop-oxy_on	Orthosteric Ligand	v2_on
25.93	Consensus	vasop-oxy_on_gp	Orthosteric Ligand	v2_on_gp
25.81	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
25.81	Consensus	crf1_on	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
25.81	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
25.00	Single	2HPY	All-trans-Retinal	2HPY-Rhodopsin-All-trans-Retinal
25.00	Single	3EML	ZM-241385	3EML-A_2A-ZM-241385
25.00	Single	5K2A	ZM-241385	5K2A-A_2A-ZM-241385-Na
25.00	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
25.00	Single	5VRA	ZM-241385	5VRA-A_2A-ZM-241385-Na
25.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
25.00	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/β1/γ2
25.00	Single	6LPJ	ZM-241385	6LPJ-A_2A-ZM-241385-Na
25.00	Single	6LPK	ZM-241385	6LPK-A_2A-ZM-241385-Na
25.00	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/β1/γ2
25.00	Single	6OY9	All-trans-Retinal	6OY9-Rhodopsin-All-trans-Retinal-Gt/β1/γ1
25.00	Single	6S0L	ZM-241385	6S0L-A_2A-ZM-241385
25.00	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
25.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/β1/γ2
25.00	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
25.00	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
25.00	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/β1/γ2
25.00	Single	7V3Z	CP55940	7V3Z-CB₁-CP55940
25.00	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
25.00	Single	7X9B	Neuropeptide-Y	7X9B-Y₂-Neuropeptide-Y-Gi1/β1/γ2
25.00	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/β1/γ2
25.00	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
25.00	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/β1/γ2
25.00	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/β1/γ2
25.00	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/β1/γ2
25.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/β1/γ2
25.00	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
25.00	Single	8RW7	StilSwitch1	8RW7-A_2A-StilSwitch1-Na
25.00	Single	8X3L	XWD	8X3L-CB₂-XWD-Gi1/β1/γ2
25.00	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/β1/γ2
25.00	Single	8ZBE	Octreotide	8ZBE-SST5-Octreotide-Gi1/β1/γ1
25.00	Single	8ZQE	GPR15L(C11)	8ZQE-GPR15-GPR15L(C11)-Gi1/β1/γ1
25.00	Single	8ZRT	ET-1	8ZRT-ET_B-ET-1
25.00	Single	9H37	A1IR0	9H37-A_2A-A1IR0-Na
25.00	Single	9IPY	JR14a	9IPY-C3a_B-JR14a
25.00	Single	9IZC	MK1903	9IZC-HCA₂-MK1903-Gi1/β1/γ2
25.00	Single	9JGK	Balovaptan	9JGK-5-HT_2B-Balovaptan
25.00	Single	9V2N	Macimorelin	9V2N-Ghrelin-Macimorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
25.00	Consensus	etb_on_gp	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
25.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/β1/γ2 7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/β1/γ2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/β1/γ2
25.00	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
25.00	Consensus	mc1_on_gp	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
25.00	Consensus	nucleotide_offon	Orthosteric Ligand	nucleotide_off nucleotide_on
25.00	Consensus	nucleotide_offon_gp	Orthosteric Ligand	nucleotide_on_gp nucleotide_off
24.24	Consensus	crf1_on_gp	Orthosteric Ligand	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2 6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
24.24	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_melanocortin gs_vasop-oxy
24.14	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
24.14	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/β1/γ2
24.14	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/β1/γ2
24.14	Consensus	gi_compl-pept	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 8IA8-C3a_B-E7 peptide-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
24.00	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
24.00	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2
24.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/β1/γ2
24.00	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/β1/γ2
24.00	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/β1/γ2
24.00	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
24.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/β1/γ2
24.00	Single	8WZ2	Orexigenic Neuropeptide QRFP	8WZ2-QRFP-Orexigenic Neuropeptide QRFP-chim(NtGi1L-Gs-CtGq)/β1/γ2
24.00	Single	8ZCJ	Pasireotide	8ZCJ-SST5-Pasireotide-Gi1/β1/γ1
24.00	Single	8ZJD	Kisspeptin-10	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
24.00	Single	9BKJ	Cholecystokinin-8	9BKJ-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs-CtGq)/β1/γ2
24.00	Consensus	gq_kisspeptin	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
24.00	Consensus	kiss1_on_gp	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
24.00	Consensus	kisspeptin_on_gp	Orthosteric Ligand	kiss1_on_gp
24.00	Consensus	p2y_on	Orthosteric Ligand	p2y1_on p2y10_on p2y12_on
23.81	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
23.81	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
23.81	Single	5N2S	PSB36	5N2S-A₁-PSB36
23.81	Single	5NM2	ZM-241385	5NM2-A_2A-ZM-241385-Na
23.81	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
23.81	Single	6LPL	ZM-241385	6LPL-A_2A-ZM-241385-Na
23.81	Single	6S0Q	ZM-241385	6S0Q-A_2A-ZM-241385
23.81	Single	6WQA	ZM-241385	6WQA-A_2A-ZM-241385-Na
23.81	Single	7C4S	S1P	7C4S-S1P₃-S1P
23.81	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
23.81	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
23.81	Single	7RM5	ZM-241385	7RM5-A_2A-ZM-241385-Na
23.81	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
23.81	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
23.81	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/β1/γ2
23.81	Single	7W41	PD176252	7W41-BB₂-PD176252
23.81	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/β1/γ2
23.81	Single	8FYN	ZM-241385	8FYN-A_2A-ZM-241385-Na
23.81	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
23.81	Single	8ID4	Linoleic acid	8ID4-FFA4-Linoleic acid-Gi1/β1/γ2
23.81	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
23.81	Single	8S4D	CMF-019	8S4D-Apelin-CMF-019
23.81	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine-chim(NtGi1-Gq)/β1/γ2
23.81	Single	8TF5	Oleic acid	8TF5-GPR6-Oleic acid
23.81	Single	8YNS	SNAP-94847	8YNS-MCH1-SNAP-94847
23.81	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/β1/γ2
23.81	Single	9ERX	D9-THC analog	9ERX-CB₁-D9-THC analog-Gi1/β1/γ2
23.81	Single	9IYB	Prostaglandin	9IYB-DP₂-Prostaglandin-A1D5Q-Gi1/β1/γ2
23.81	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
23.81	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
23.81	Consensus	blt1_off	Orthosteric Ligand	5X33-BLT₁-BIIL260 7K15-BLT₁-MKD046-Na
23.81	Consensus	blt_off	Orthosteric Ligand	blt1_off
23.81	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
23.81	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on lpl_on prostanoid_on leukotriene_on
23.81	Consensus	lipid_on_gp	Orthosteric Ligand	cannabinoid_on_gp ffa_on_gp lpl_on_gp prostanoid_on_gp leukotriene_on_gp
23.81	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
23.81	Consensus	rxfp4_on_gp	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
23.53	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
23.53	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
23.53	Single	5WKT	Octyl-Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl-β-D-Glucopyranoside-Gt(CT)
23.53	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
23.53	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
23.53	Single	7MT8	All-trans-Retinal	7MT8-Rhodopsin-All-trans-Retinal-GRK1
23.53	Single	7MT9	All-trans-Retinal	7MT9-Rhodopsin-All-trans-Retinal-GRK1
23.53	Single	7MTA	All-trans-Retinal	7MTA-Rhodopsin-All-trans-Retinal-GRK1
23.53	Single	7X9A	Neuropeptide-Y	7X9A-Y₁-Neuropeptide-Y-Gi1/β1/γ2
23.53	Single	8EIT	Doconexent	8EIT-FFA1-Doconexent-chim(NtGi1L-Gs-CtGq)/β1/γ2
23.53	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
23.53	Single	9IV1	5alpha-DHT	9IV1-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
23.53	Consensus	gi_opsins	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
23.53	Consensus	gi_sensory	Orthosteric Ligand	gi_opsins
23.53	Consensus	opsin1lw_on	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
23.53	Consensus	opsin1lw_on_gp	Orthosteric Ligand	8IU2-Opsin1LW-Retinal-Gi1/β1/γ2
23.33	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/β1/γ2
23.33	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
23.08	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
23.08	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/β1/γ2
23.08	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/β1/γ2
23.08	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/β1/γ2
23.08	Single	8XYD	Platelet Activating Factor	8XYD-PAF-Platelet Activating Factor-Gi1/β1/γ2
23.08	Single	8Z7J	Agonistic antibody	8Z7J-Apelin-Agonistic antibody-Gi1/β1/γ2
23.08	Single	9EAI	Nanobody AT209	9EAI-AT₁-Losartan-Nanobody AT209
23.08	Single	9IQS	Muscarinic toxin 3	9IQS-M₄-Muscarinic toxin 3
23.08	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
23.08	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
22.73	Single	5XRA	AM11542	5XRA-CB₁-AM11542
22.73	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/β1/γ2
22.73	Single	7WV9	CP55940	7WV9-CB₁-CP55940-ZCZ011-Gi2/β1/γ2
22.73	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/β1/γ2
22.73	Single	8ID6	Oleic acid	8ID6-FFA4-Oleic acid-Gi1/β1/γ2
22.73	Single	8JSR	Anamorelin	8JSR-Ghrelin-Anamorelin-chim(NtGi1-Gs-CtGq)/β1/γ2
22.73	Single	8JZP	C5A anaphylatoxin	8JZP-C5a₁-C5A anaphylatoxin-Go/β1/γ2
22.73	Single	8WJX	ADP	8WJX-P2Y₁-ADP-chim(Gs-CtGq)/β1/γ2
22.73	Single	8XIP	Pasireotide	8XIP-SST1-Pasireotide-chim(NtGi1-Gs-CtGi1)/β1/γ2
22.73	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/β1/γ2
22.73	Single	9B65	KCA	9B65-CB₁-KCA-Gi1/β1/γ2
22.73	Single	9EGO	YVF	9EGO-CB₁-YVF-Gi1/β1/γ2
22.73	Single	9IK9	SST analogue	9IK9-SST1-SST analogue-Gi1/β1/γ2
22.73	Single	9JMC	DS-3801b	9JMC-Motilin-DS-3801b-chim(Gs-CtGq)/β1/γ2
22.73	Consensus	cyslt1_off	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
22.73	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/β1/γ2 7YJ4-RXFP4-INSL5-Gi2/β1/γ2 7YK6-RXFP4-PubChem 138319674-Gi2/β1/γ2
22.73	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
22.73	Consensus	relaxin_on_gp	Orthosteric Ligand	rxfp4_on_gp
22.58	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/β1/γ2
22.58	Single	7VGX	Neuropeptide-Y	7VGX-Y₁-Neuropeptide-Y-Gi1/β1/γ2
22.58	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2
22.58	Consensus	etb_on	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/β1/γ2 8HBD-ET_B-IRL1620-Gi1/β1/γ2
22.22	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
22.22	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
22.22	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
22.22	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
22.22	Single	6QNO	All-trans-Retinal	6QNO-Rhodopsin-All-trans-Retinal-Gi1/β1/γ1
22.22	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
22.22	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
22.22	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/β1/γ2
22.22	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
22.22	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
22.22	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
22.22	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/β1/γ2
22.22	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/β1/γ2
22.22	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/β1/γ2
22.22	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/β1/γ2
22.22	Single	8K6N	Pro-neuropeptide-Y	8K6N-Y₂-Pro-neuropeptide-Y-Gi2/β1/γ1
22.22	Single	8RWH	StilSwitch2	8RWH-A_2A-StilSwitch2-Na
22.22	Single	8W8Y	Gamma-MSH	8W8Y-MC₃-γ-MSH-Ca-Gs/β1/γ2
22.22	Single	9EPR	Retinal	9EPR-Rhodopsin-Retinal-Gi1/β1/γ2
22.22	Single	9IQT	Niacin	9IQT-HCA₂-Niacin-Gi1/β1/γ2
22.22	Single	9IZD	CHBA	9IZD-HCA₁-CHBA-Gi1/β1/γ2
22.22	Single	9L3Z	LRH7-C2	9L3Z-CML1-LRH7-C2
22.22	Single	9M1O	Morphine-Modulating Neuropeptide B	9M1O-NPFF2-Morphine-Modulating Neuropeptide B-Gi1/β1/γ2
22.22	Consensus	c5a1_on	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
22.22	Consensus	compl-peptide_on_gp	Orthosteric Ligand	c5a1_on_gp c3a_on_gp
22.22	Consensus	gq_nucleotide	Orthosteric Ligand	gq_p2y
22.22	Consensus	gq_p2y	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
22.22	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/β1/γ1
22.22	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
22.22	Consensus	mc2_on_gp	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
21.88	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
21.88	Consensus	ccr5_on_gp	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
21.74	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
21.74	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
21.74	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/β1/γ2
21.74	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/β1/γ2
21.74	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
21.74	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/β1/γ2
21.74	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/β1/γ2
21.74	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/β1/γ2
21.74	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4-Eicosapentaenoic acid-Gi1/β1/γ2
21.74	Single	8JD3	JNJ-40411813	8JD3-mGlu2; mGlu3-Glutamate-JNJ-40411813-Gi1/β1/γ2
21.74	Single	9BJK	NAM	9BJK-μ-Naloxone-NAM
21.74	Consensus	cb1_on	Orthosteric Ligand	6KPG-CB₁-AM841-Gi1/β1/γ2 8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/β1/γ2
21.74	Consensus	leukotriene_off	Orthosteric Ligand	blt_off cyslt_off
21.74	Consensus	lipid_offon	Orthosteric Ligand	lipid_off lipid_on
21.74	Consensus	lipid_offon_gp	Orthosteric Ligand	lipid_on_gp lipid_off
21.74	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z35-LPA₁-ONO-9910539 4Z34-LPA₁-ONO-9780307
21.74	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
21.62	Consensus	pth2_on_gp	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
21.43	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/β1/γ2
21.43	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2
21.43	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/β1/γ2
21.43	Single	7T10	Somatostatin-14	7T10-SST2-Somatostatin-14-Gi3/β1/γ2
21.43	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/β1/γ2
21.43	Consensus	apelin_on	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
21.43	Consensus	apelin_on_gp	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
21.43	Consensus	c5a1_on_gp	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/β1/γ2 7Y66-C5a₁-BM213-Gi1/β1/γ2 7Y67-C5a₁-C089 peptide-Gi1/β1/γ2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/β1/γ2
21.43	Consensus	mc5_on_gp	Orthosteric Ligand	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2
21.43	Consensus	protein_offon	Orthosteric Ligand	protein_off protein_on
21.43	Consensus	protein_offon_gp	Orthosteric Ligand	protein_on_gp protein_off
21.21	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/β1/γ2
21.21	Consensus	endothelin_on_gp	Orthosteric Ligand	etb_on_gp eta_on_gp
21.21	Consensus	melanocortin_on	Orthosteric Ligand	mc1_on mc4_on mc2_on mc3_on mc5_on
21.21	Consensus	melanocortin_on_gp	Orthosteric Ligand	mc1_on_gp mc4_on_gp mc2_on_gp mc3_on_gp mc5_on_gp
21.05	Single	3PWH	ZM-241385	3PWH-A_2A-ZM-241385
21.05	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
21.05	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
21.05	Single	5K2D	ZM-241385	5K2D-A_2A-ZM-241385-Na
21.05	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
21.05	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
21.05	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
21.05	Single	6JZH	ZM-241385	6JZH-A_2A-ZM-241385-Na
21.05	Single	6PS7	ZM-241385	6PS7-A_2A-ZM-241385-Na
21.05	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
21.05	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
21.05	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
21.05	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143
21.05	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
21.05	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2
21.05	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/β1/γ2
21.05	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
21.05	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/β1/γ2
21.05	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/β1/γ2
21.05	Single	8RVW	StilSwitch3	8RVW-A_2A-StilSwitch3-Na
21.05	Single	8RW4	AzoSwitch2	8RW4-A_2A-AzoSwitch2-Na
21.05	Single	8RWE	StilSwitch4	8RWE-A_2A-StilSwitch4-Na
21.05	Single	8UTD	MK1903	8UTD-HCA₂-MK1903-Gi1/β1/γ2
21.05	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
21.05	Single	8XXV	Indomethacin	8XXV-DP₂-Indomethacin-A1D5Q-Gi1/β1/γ2
21.05	Single	9FUP	Istradefylline	9FUP-A_2A-Istradefylline-Na
21.05	Single	9J5V	CpY	9J5V-LPA₁-CpY-Gi1/β1/γ2
21.05	Single	9K6L	SA0	9K6L-TAS2R16-SA0-Gi2/β1/γ2
21.05	Single	9KPE	SA0	9KPE-TAS2R16-SA0-Gi1/β1/γ2
21.05	Consensus	p2y1_on	Orthosteric Ligand	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/β1/γ2
21.05	Consensus	s1p1_off	Orthosteric Ligand	3V2W-S1P₁-PubChem 51892645
20.83	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
20.83	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
20.83	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
20.83	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
20.83	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/β1/γ2
20.83	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/β1/γ2
20.83	Single	8ID8	TUG-891	8ID8-FFA4-TUG-891-Gi1/β1/γ2
20.83	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/β1/γ2
20.83	Single	8WRZ	PubChem 102336704	8WRZ-CB₁-PubChem 102336704-Arrestin2
20.83	Single	8XGS	Metastin	8XGS-Kiss1-Metastin-chim(NtGi1-Gq)/β1/γ2
20.83	Single	8XJK	Cloprosetnol	8XJK-FP-alpha-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Single	8ZX4	Lysophosphatidylinositol	8ZX4-GPR55-Lysophosphatidylinositol-chim(NtGi1-G13)/β1/γ2
20.83	Single	9IZF	NKP	9IZF-LPA₁-NKP-Gi1/β1/γ2
20.83	Consensus	fp-alpha_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Consensus	fp-alpha_on_gp	Orthosteric Ligand	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
20.83	Consensus	peptide_off	Orthosteric Ligand	cck_off angiotensin_off bombesin_off endothelin_off ghrelin_off npy_off opioid_off orexin_off somatostatin_off tachykinin_off vasop-oxy_off neurotensin_off
20.69	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/β1/γ2
20.69	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
20.69	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/β1/γ2
20.69	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/β1/γ2
20.69	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/β1/γ2
20.69	Single	8XVH	Endothelin-1	8XVH-ET_B-Endothelin-1-chim(Gs-CtGq)/β1/γ2
20.69	Consensus	chemokine_off	Orthosteric Ligand	ccr_off cxcr_off
20.69	Consensus	chemokine_on_gp	Orthosteric Ligand	ccr_on_gp cxcr_on_gp
20.69	Consensus	cxcr_off	Orthosteric Ligand	cxcr3_off cxcr4_off
20.69	Consensus	gi_apelin	Orthosteric Ligand	8XZH-Apelin-MM07-Gi1/β1/γ2 7W0M-Apelin-PubChem 122701908-Gi1/β1/γ2 8XZJ-Apelin-WN353-Gi1/β1/γ2 8XZF-Apelin-WN561-Gi1/β1/γ2 8XZG-Apelin-Apelin-13-Gi1/β1/γ2
20.69	Consensus	gi_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2 8HNK-CXCR3-CXCL11-Gi1/β1/γ2 8K3Z-CXCR4-CXCL12-Gi1/β1/γ1 8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2 6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2 8KFX-CCR8-LMD-009-Gi1/β1/γ2 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2 8HNL-CXCR3-PS372424-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 8U1U-CCR8-CCL1-Gi1/β1/γ2 7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2 7XA3-CCR2-CCL2-Gi1/β1/γ2
20.69	Consensus	vpac1_on	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
20.59	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
20.00	Single	4A4M	All-trans-Retinal	4A4M-Rhodopsin-All-trans-Retinal-Gt(CT)
20.00	Single	5EN0	All-trans-Retinal	5EN0-Rhodopsin-All-trans-Retinal-Gt(CT)
20.00	Single	5IU4	ZM-241385	5IU4-A_2A-ZM-241385-Na
20.00	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
20.00	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
20.00	Single	5JTB	ZM-241385	5JTB-A_2A-ZM-241385
20.00	Single	5K2C	ZM-241385	5K2C-A_2A-ZM-241385-Na
20.00	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
20.00	Single	5NM4	ZM-241385	5NM4-A_2A-ZM-241385-Na
20.00	Single	5UVI	ZM-241385	5UVI-A_2A-ZM-241385
20.00	Single	6AQF	ZM-241385	6AQF-A_2A-ZM-241385
20.00	Single	6MH8	ZM-241385	6MH8-A_2A-ZM-241385
20.00	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
20.00	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/β1/γ2
20.00	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
20.00	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/β1/γ2
20.00	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
20.00	Single	7BB6	AVP	7BB6-V₂-AVP-Gs/β1/γ2
20.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
20.00	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-α-factor mating pheromone
20.00	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/β1/γ2
20.00	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
20.00	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/β1/γ2
20.00	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/β1/γ2
20.00	Single	8HQN	9-S-HODE	8HQN-GPR132-9-S-HODE-Gi1/β1/γ2
20.00	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8QJ2	pN162	8QJ2-MC₄-pN162-Gs
20.00	Single	8RQQ	ZM-241385	8RQQ-A_2A-ZM-241385-Na
20.00	Single	8WCB	Cyclohexylammonium Ion	8WCB-TA1-Cyclohexylammonium Ion-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	8WCC	Cyclohexylammonium Ion	8WCC-TA1-Cyclohexylammonium Ion
20.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
20.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
20.00	Single	8Y6Y	GLPG0974	8Y6Y-FFA2-GLPG0974
20.00	Single	8ZPN	AMD3100	8ZPN-CXCR4-AMD3100
20.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9ASB	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9ASB-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
20.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9EAJ	Nanobody AT209	9EAJ-AT₁-Nanobody AT209
20.00	Single	9JH6	C20:0 Ceramide	9JH6-CysLT₂-C20:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
20.00	Single	9M2F	Neuropeptide FF	9M2F-NPFF1-Neuropeptide FF-Gi1/β1/γ2
20.00	Consensus	a2_off	Orthosteric Ligand	a2a_off
20.00	Consensus	a2a_off	Orthosteric Ligand	3RFM-A_2A-Caffeine 8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-2-118 8PWN-A_2A-Theophylline 5IU4-A_2A-ZM-241385-Na 5OLZ-A_2A-PubChem 135566609-Na 6GT3-A_2A-Imaradenant-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PSB-36-Na 5IU7-A_2A-Q27456346-Na 5OLH-A_2A-Vipadenant-Na 5OLO-A_2A-Tozadenant-Na 6ZDR-A_2A-HMS1413f12-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5IU8-A_2A-Q27456347-Na 5IUB-A_2A-Q27456344-Na 6ZDV-A_2A-Chromone 5d-Na 5IUA-A_2A-Q27456348-Na 8A2P-A_2A-LUAA47070-Na
20.00	Consensus	class-a_class-b1_cons_on_gp	Orthosteric Ligand	class-a_on_gp class-b1_on_gp
20.00	Consensus	crf2_on_gp	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
20.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II 3OE0-CXCR4-CVX15 3OE6-CXCR4-IT1t
20.00	Consensus	cxcr_on_gp	Orthosteric Ligand	cxcr3_on_gp cxcr4_on_gp cxcr1_on_gp cxcr2_on_gp
20.00	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
20.00	Consensus	kiss1_on	Orthosteric Ligand	8ZJD-Kiss1-Kisspeptin-10-chim(NtGi1-Gq)/β1/γ1
20.00	Consensus	kisspeptin_on	Orthosteric Ligand	kiss1_on
20.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
20.00	Consensus	pac_on_gp	Orthosteric Ligand	pac1_on_gp
20.00	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/β1/γ2
20.00	Consensus	secretin_on	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
20.00	Consensus	vpac1_on_gp	Orthosteric Ligand	8E3Z-VPAC₁-VIP-Gs/β1/γ2
19.44	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
19.35	Single	7F53	Alpha-MSH	7F53-MC₄-α-MSH-Gs/β1/γ2
19.35	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
19.35	Single	8W8W	Alpha-MSH	8W8W-MC₃-α-MSH-Ca-Gs/β1/γ2
19.35	Single	9BUC	Cagrilintide	9BUC-CT-Cagrilintide-Gs/β1/γ2
19.35	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
19.35	Consensus	glp_on_gp	Orthosteric Ligand	glp1_on_gp glp2_on_gp
19.35	Consensus	p2y10_on_gp	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
19.35	Consensus	secretin_on_gp	Orthosteric Ligand	7D3S-Secretin-Secretin-Gs/β1/γ2
19.23	Single	7QA8	Peptide	7QA8-STE2-Peptide
19.23	Single	7QA8	Peptide	7QA8-STE2-Peptide
19.23	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
19.23	Single	8K3Z	CXCL12	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
19.23	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Gi1/β1/γ2
19.23	Single	8WKY	PG-934	8WKY-MC₄-PG-934
19.23	Single	8XGM	Chemerin	8XGM-CML2-Chemerin-Gi1/β1/γ2
19.23	Single	9HB3	Mambaquaretin-1	9HB3-V₂-Mambaquaretin-1
19.23	Single	9L3Y	Retinoic acid receptor responder protein 2	9L3Y-CML2-Retinoic acid receptor responder protein 2-Gi1/β1/γ2
19.23	Consensus	cxcr4_on	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
19.23	Consensus	nmur1_on_gp	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
19.23	Consensus	somatostatin_off	Orthosteric Ligand	sst2_off
19.05	Single	4EIY	ZM-241385	4EIY-A_2A-ZM-241385-Na
19.05	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
19.05	Single	5OLG	ZM-241385	5OLG-A_2A-ZM-241385-Na
19.05	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
19.05	Single	5UEN	DU172	5UEN-A₁-DU172
19.05	Single	6GPS	MK0812	6GPS-CCR2-MK0812
19.05	Single	6XBM	5LWE	6XBM-SMO-5LWE-Gi1/β1/γ2
19.05	Single	7CFM	P395	7CFM-GPBA-P395-Gs/β1/γ2
19.05	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
19.05	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/β1/γ2
19.05	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/β1/γ2
19.05	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/β1/γ2
19.05	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1
19.05	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
19.05	Single	9AVG	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVG-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs)/β1/γ2
19.05	Single	9IYA	ONO-9710531	9IYA-GPR55-ONO-9710531
19.05	Consensus	alicarboxylic_off	Orthosteric Ligand	succinate_off
19.05	Consensus	ccr2_off	Orthosteric Ligand	6GPS-CCR2-MK0812
19.05	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off paf_off lpl_off prostanoid_off leukotriene_off
19.05	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
18.75	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
18.75	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/β1/γ2
18.75	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/β1/γ2
18.75	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-α-factor mating pheromone
18.75	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
18.75	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
18.75	Single	8F0K	Pramlintide Analogue San385	8F0K-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
18.75	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
18.75	Single	8KGG	LPS	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
18.75	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
18.75	Single	9BYO	Exendin-3	9BYO-GLP-1-Exendin-3-Gs/β1/γ2
18.75	Single	9IV2	5alpha-DHT	9IV2-ADGRD1-5α-DHT-chim(NtGi1-Gs)/β1/γ2
18.75	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
18.75	Consensus	gs_melanocortin	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2 8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2 8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/β1/γ2; MRAP1 8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/β1/γ2 7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2
18.52	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
18.52	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/β1/γ2
18.52	Single	9IQR	Muscarinic toxin 3	9IQR-α_2a-Muscarinic toxin 3
18.52	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
18.42	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/β1/γ2
18.18	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
18.18	Single	5N2R	PSB-36	5N2R-A_2A-PSB-36-Na
18.18	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
18.18	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
18.18	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
18.18	Single	6GPX	MK0812	6GPX-CCR2-MK0812
18.18	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/β1/γ2
18.18	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
18.18	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/β1/γ2
18.18	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
18.18	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/β1/γ2
18.18	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/β1/γ2
18.18	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/β1/γ2
18.18	Single	8QOT	Nanobody-E	8QOT-μ-Nanobody-E
18.18	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/β1/γ2
18.18	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
18.18	Single	8X0C	VU0424465	8X0C-mGlu5; mGlu5-Quisqualate-VU0424465
18.18	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
18.18	Single	8X0D	VU0424465	8X0D-mGlu5; mGlu5-Quisqualate-VU0424465
18.18	Single	9GE2	ML184	9GE2-GPR55-ML184-chim(NtGi1-G13)/β1/γ2
18.18	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
18.18	Consensus	class-a_class-b1_cons_on	Orthosteric Ligand	class-a_on class-b1_on
18.18	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
18.18	Consensus	ep_off	Orthosteric Ligand	ep4_off
18.18	Consensus	s1p_off	Orthosteric Ligand	s1p1_off s1p5_off
17.86	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
17.86	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/β1/γ2; RAMP2
17.86	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
17.86	Single	7F4D	Alpha-MSH	7F4D-MC₁-α-MSH-chim(NtGi1-Gs)/β1/γ2
17.86	Single	7O7F	6P4-CCL5	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1
17.86	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/β1/γ2
17.86	Single	8K6M	Neuropeptide-Y	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
17.86	Single	8WKZ	SBL-MC-31	8WKZ-MC₄-SBL-MC-31
17.86	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/β1/γ2
17.86	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/β1/γ2
17.86	Consensus	ccr_on	Orthosteric Ligand	ccr6_on ccr8_on ccr2_on ccr1_on ccr5_on
17.86	Consensus	cxcr4_on_gp	Orthosteric Ligand	8K3Z-CXCR4-CXCL12-Gi1/β1/γ1
17.86	Consensus	npy1_on	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
17.86	Consensus	npy1_on_gp	Orthosteric Ligand	8K6M-Y₁-Neuropeptide-Y-Gi2/β1/γ1
17.65	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
17.65	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
17.65	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/β1/γ1
17.65	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
17.65	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
17.65	Single	8XOF	Lys05	8XOF-GPR30-Lys05-chim(NtGi1-Gs-CtGq)/β1/γ2
17.65	Single	8Y02	Retinal	8Y02-OPN1SW-Retinal-Gi1/β1/γ2
17.50	Consensus	pth_on_gp	Orthosteric Ligand	pth1_on_gp pth2_on_gp
17.39	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
17.39	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
17.39	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
17.39	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
17.39	Single	7FEE	CP55940	7FEE-CB₁-CP55940-ZCZ011
17.39	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
17.39	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/β1/γ2
17.39	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
17.39	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
17.39	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-chim(NtGi1-Gq)/β1/γ2
17.39	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/β1/γ2
17.39	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones α chain-Compound 716340-Gs/β1/γ2
17.39	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-α-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
17.39	Single	8X0F	VU0424465	8X0F-mGlu5; mGlu5-Quisqualate-VU0424465
17.39	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/β1/γ2
17.39	Single	8YNT	SNAP-94847	8YNT-MCH1-SNAP-94847
17.39	Single	9AST	Lymphotactin	9AST-XCR1-Lymphotactin-Gi1/β1/γ2
17.39	Consensus	motilin_on	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	nk2_on_gp	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
17.39	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
17.39	Consensus	npy_off	Orthosteric Ligand	npy1_off npy2_off
17.39	Consensus	protein_off	Orthosteric Ligand	chemokine_off grh_off
17.24	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/β1/γ2
17.24	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
17.24	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
17.24	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/β1/γ2
17.24	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2
17.24	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
17.24	Single	8YW3	Retatrutide	8YW3-GLP-1-Retatrutide-Gs/β1/γ2
17.24	Single	8YW5	Retatrutide	8YW5-Glucagon-Retatrutide-Gs/β1/γ2
17.24	Single	9BLC	Cagrilintide backbone (non-acylated)	9BLC-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
17.24	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/β1/γ2
17.14	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
17.14	Consensus	crf_on_gp	Orthosteric Ligand	crf2_on_gp crf1_on_gp
17.14	Consensus	glp1_on_gp	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
17.14	Consensus	pth1_on_gp	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
16.67	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
16.67	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
16.67	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
16.67	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
16.67	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
16.67	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
16.67	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/β1/γ2
16.67	Single	6KQI	CP55940	6KQI-CB₁-CP55940-Org27569
16.67	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/β1/γ2
16.67	Single	6OS2	TRV026	6OS2-AT₁-TRV026
16.67	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
16.67	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/β1/γ2
16.67	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/β1/γ2
16.67	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/β1/γ2
16.67	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/β1/γ2
16.67	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
16.67	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/β1/γ2
16.67	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/β1/γ2
16.67	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/β1/γ2
16.67	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/β1/γ2
16.67	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	8IBU	Erythromycin-A	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/β1/γ2
16.67	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/β1/γ2
16.67	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/β1/γ2
16.67	Single	8X9U	Metenolone	8X9U-ADGRD1-Metenolone-chim(NtGi1-Gs)/β1/γ2
16.67	Single	8XJN	Cloprosetnol	8XJN-TXA2-Cloprosetnol-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Single	9GGG	I-BOP	9GGG-TXA2-I-BOP-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.67	Single	9IZH	LPA	9IZH-LPA₁-LPA-chim(NtGi2-G13)/β1/γ2
16.67	Single	9JHJ	C18:0 Ceramide	9JHJ-FPR2-ALX-C18:0 Ceramide-Gi1/β1/γ2
16.67	Consensus	ccr8_on	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
16.67	Consensus	ccr_on_gp	Orthosteric Ligand	ccr6_on_gp ccr8_on_gp ccr2_on_gp ccr1_on_gp ccr5_on_gp
16.67	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	eta_on_gp	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	ffa2_on_gp	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
16.67	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
16.67	Consensus	ffa3_on_gp	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2
16.67	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
16.67	Consensus	galanin_on_gp	Orthosteric Ligand	gal2_on_gp gal1_on_gp
16.67	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
16.67	Consensus	motilin_on_gp	Orthosteric Ligand	8IBU-Motilin-Erythromycin-A-chim(NtGi1-Gs-CtGq)/β1/γ2
16.67	Consensus	p2y10_on	Orthosteric Ligand	8KGG-P2Y10-LPS-chim(NtGi2-G13)/β1/γ2
16.67	Consensus	pac_on	Orthosteric Ligand	pac1_on
16.22	Consensus	gluc_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
16.22	Consensus	glucagon_on_gp	Orthosteric Ligand	glp_on_gp gluc_on_gp secretin_on_gp gip_on_gp
16.13	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
16.13	Single	6FJ3	PTH	6FJ3-PTH1-PTH
16.13	Single	6NBF	Long-Acting PTH Analog	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
16.13	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/β1/γ2
16.13	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/β1/γ2
16.13	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
16.13	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/β1/γ2
16.13	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/β1/γ2
16.13	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2
16.13	Single	8XQF	Apelin-13	8XQF-Apelin-Apelin-13-Gi1/β1/γ2
16.13	Single	9BLW	Cagrilintide backbone (non-acylated)	9BLW-CT (AMY1)-Cagrilintide backbone (non-acylated)-Gs/β1/γ2; RAMP1
16.13	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
16.13	Consensus	ccr_off	Orthosteric Ligand	ccr2_off ccr5_off
16.13	Consensus	pac1_on	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
16.13	Consensus	pac1_on_gp	Orthosteric Ligand	8E3X-PAC₁-PACAP27-Gs/β1/γ2 6M1H-PAC₁-Maxadilan-Gs/β1/γ2
16.00	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
16.00	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/β1/γ1
16.00	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/β1/γ2
16.00	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/β1/γ2
16.00	Single	8XJO	U46619	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Single	9C0K	Exendin-4	9C0K-GLP-1-Exendin-4-Gs/β1/γ2
16.00	Single	9M1H	Prostaglandin E2	9M1H-EP₁-Prostaglandin E2-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	cyslt2_off	Orthosteric Ligand	6RZ7-CysLT₂-ONO-2570366 6RZ8-CysLT₂-ONO-2080365 6RZ9-CysLT₂-ONO-2770372
16.00	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.00	Consensus	gal2_on_gp	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/β1/γ2
16.00	Consensus	prostanoid_on	Orthosteric Ligand	tp_on fp-alpha_on
16.00	Consensus	prostanoid_on_gp	Orthosteric Ligand	tp_on_gp fp-alpha_on_gp
16.00	Consensus	tp_on	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
16.00	Consensus	tp_on_gp	Orthosteric Ligand	8XJO-TXA2-U46619-chim(NtGi1-Gs-CtGq)/β1/γ2
15.79	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
15.79	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
15.79	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/β1/γ2
15.79	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/β1/γ2
15.79	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/β1/γ2
15.79	Single	8X2K	Oleic monoethanolamide	8X2K-GPR3-Oleic monoethanolamide-chim(NtGi1-Gs)/β1/γ2
15.79	Single	9B9Y	7DY	9B9Y-CB₁-7DY
15.79	Single	9LMP	NE52-QQ57	9LMP-GPR4-NE52-QQ57
15.79	Consensus	gluc_on_gp	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/β1/γ2 8JIT-Glucagon-MEDI0382-Gs/β1/γ2 7V35-Glucagon-Peptide-20-Gs/β1/γ2
15.62	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/β1/γ2
15.62	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/β1/γ2
15.62	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-α-factor mating pheromone-Gi1/STE4/γ2
15.62	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/β1/γ2; RAMP1
15.62	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/β1/γ2
15.62	Single	8W8X	Beta-MSH	8W8X-MC₃-β-MSH-Ca-Gs/β1/γ2
15.62	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
15.62	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
15.62	Consensus	glp2_on_gp	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/β1/γ2
15.38	Single	5VBL	Apelin mimetic peptide agonist	5VBL-Apelin-Apelin mimetic peptide agonist
15.38	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
15.38	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/β1/γ2
15.38	Single	7RMG	Substance-P	7RMG-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
15.38	Single	7RMH	Substance-P	7RMH-NK₁-Substance-P-Gs/β1/γ2
15.38	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/β1/γ2
15.38	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/β1/γ2
15.38	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/β1/γ2
15.38	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
15.38	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
15.38	Single	8Z74	Agonistic antibody	8Z74-Apelin-Agonistic antibody
15.38	Single	9JF4	PD168368	9JF4-BB₁-PD168368
15.38	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on vip-pacap_on pth_on crf_on calcitonin_on
15.38	Consensus	nmur1_on	Orthosteric Ligand	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
15.15	Single	6LML	Glucagon	6LML-Glucagon-Glucagon-Gi1/β1/γ1
15.15	Single	6NBH	Long-Acting PTH Analog	6NBH-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
15.15	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/β1/γ2
15.15	Consensus	pth1_on	Orthosteric Ligand	6NBF-PTH1-Long-Acting PTH Analog-Gs/β1/γ2 8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2 8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2 7Y36-PTH1-Teriparatide-Gs/β1/γ2 7Y35-PTH1-Abaloparatide-Gs/β1/γ2
15.15	Consensus	vip-pacap_on	Orthosteric Ligand	vpac_on pac_on
15.15	Consensus	vip-pacap_on_gp	Orthosteric Ligand	vpac_on_gp pac_on_gp
15.15	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
15.15	Consensus	vpac2_on_gp	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
15.00	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
15.00	Single	3VG9	ZM-241385	3VG9-A_2A-ZM-241385-Antibody
15.00	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
15.00	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
15.00	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
15.00	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
15.00	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
15.00	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
15.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
15.00	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/β1/γ2
15.00	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/β1/γ2
15.00	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/β1/γ2
15.00	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
15.00	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Gi1/β1/γ2
15.00	Single	8U8F	Palmitic Acid	8U8F-GPR3-Palmitic Acid-Gs/β1/γ2
15.00	Single	8YYW	Alpha-ketoglutarate	8YYW-Oxoglutarate-α-ketoglutarate-α-ketoglutarate-chim(Gi1-CtGq)/β1/γ2
15.00	Single	9AVL	Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AVL-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi3/β2/γ2
15.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
15.00	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
15.00	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491
14.81	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
14.81	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
14.81	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/β1/γ2
14.81	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/β1/γ2
14.81	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/β1/γ2
14.81	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
14.81	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/β1/γ2
14.81	Single	8KIG	SHU9119	8KIG-MC₃-SHU9119-Ca
14.81	Single	8YWF	Retatrutide	8YWF-GLP-1-Retatrutide-chim(NtGi1-Gs)/β1/γ2
14.81	Consensus	chemokine_on	Orthosteric Ligand	ccr_on cxcr_on
14.81	Consensus	mc4_on	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
14.81	Consensus	nk3_on	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
14.81	Consensus	nk3_on_gp	Orthosteric Ligand	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/β1/γ2
14.71	Consensus	gip_on	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
14.71	Consensus	gip_on_gp	Orthosteric Ligand	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2 7FIY-GIP-Tirzepatide-Gs/β1/γ2 7DTY-GIP-GIP-Gs/β1/γ2
14.29	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
14.29	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
14.29	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
14.29	Single	6TPK	Retosiban	6TPK-OT-Retosiban
14.29	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
14.29	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/β1/γ2
14.29	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
14.29	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2
14.29	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/β1/γ2
14.29	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/β1/γ2
14.29	Single	7RMI	Substance-P	7RMI-NK₁-Substance-P-chim(Gs-CtGq)/β1/γ2
14.29	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
14.29	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
14.29	Single	7T94	LY2119620	7T94-M₂-Acetylcholine-LY2119620-chim(NtGi1-Go)/β1/γ2
14.29	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/β1/γ2; RAMP3
14.29	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
14.29	Single	8F7Q	Beta-Endorphin	8F7Q-μ-β-Endorphin-Gi1/β1/γ2
14.29	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/β1/γ2
14.29	Single	8FLU	Long-Acting PTH	8FLU-PTH1-Long-Acting PTH-Gs/β1/γ2
14.29	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8JBH	Substance-P	8JBH-NK₃-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	8K4S	DCA-3P	8K4S-MRGPRX4-DCA-3P-chim(NtGi1L-Gs-CtGq)/β1/γ2
14.29	Single	8K6O	Pro-neuropeptide-Y	8K6O-Y₁-Pro-neuropeptide-Y-Gi2/β1/γ1
14.29	Single	8K9L	Damgo	8K9L-μ-Damgo-BMS-986122-Gi3/β1/γ1
14.29	Single	9BA0	A1AKN	9BA0-CB₁-A1AKN
14.29	Single	9IXX	LTD4	9IXX-CysLT₂-LTD4-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	9J0F	NADH	9J0F-P2Y₁₄-NADH-Gi1/β1/γ2
14.29	Single	9JFU	NE52-QQ57	9JFU-GPR4-NE52-QQ57
14.29	Single	9K0K	UTP	9K0K-P2Y₄-UTP-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	9K0X	ATP	9K0X-P2Y₂-ATP-chim(NtGi1-Gs-CtGq)/β1/γ2
14.29	Single	9K1D	Butanoic acid	9K1D-FFA2-Butanoic acid-Gi1/β1/γ2
14.29	Single	9K20	ATP	9K20-P2Y₂-ATP-chim(NtGi1-Go)/β1/γ2
14.29	Single	9KPD	SA0	9KPD-TAS2R16-SA0-chim(Gs-CtGt3)/β1/γ2
14.29	Consensus	cb1_off	Orthosteric Ligand	5U09-CB₁-Taranabant 5TGZ-CB₁-AM6538
14.29	Consensus	ccr8_on_gp	Orthosteric Ligand	8KFX-CCR8-LMD-009-Gi1/β1/γ2 8KFY-CCR8-ZK-756326-Gi1/β1/γ2 8U1U-CCR8-CCL1-Gi1/β1/γ2
14.29	Consensus	glp1_on	Orthosteric Ligand	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2 7X8R-GLP-1-BOC5-Gs/β1/γ2 6X19-GLP-1-CHU-128-Gs/β1/γ2 6X1A-GLP-1-Danuglipron-Gs/β1/γ2 6X18-GLP-1-GLP-1-Gs/β1/γ2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2 7C2E-GLP-1-PubChem 149050799-Gs/β1/γ2 7KI0-GLP-1-Semaglutide-Gs/β1/γ2 7KI1-GLP-1-Taspoglutide-Gs/β1/γ2 7X8S-GLP-1-WB4-24-Gs/β1/γ2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/β1/γ2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/β1/γ2
14.29	Consensus	mc4_on_gp	Orthosteric Ligand	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2 7F58-MC₄-THIQ-Gs/β1/γ2 7F54-MC₄-Afamelanotide-Gs/β1/γ2 7F53-MC₄-α-MSH-Gs/β1/γ2 7F55-MC₄-Bremelanotide-Gs/β1/γ2
14.29	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
14.29	Consensus	tachykinin_on_gp	Orthosteric Ligand	nk1_on_gp nk2_on_gp nk3_on_gp
14.29	Consensus	vasop-oxy_off	Orthosteric Ligand	ot_off
13.95	Consensus	class-b1_on_gp	Orthosteric Ligand	glucagon_on_gp vip-pacap_on_gp pth_on_gp crf_on_gp calcitonin_on_gp
13.89	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/β1/γ2
13.89	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/β1/γ2
13.89	Single	9JR2	PTH	9JR2-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.79	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
13.79	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/β1/γ2
13.79	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
13.79	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/β1/γ2
13.79	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
13.79	Consensus	ccr2_on_gp	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/β1/γ2
13.79	Consensus	class-b1_class-b2_cons_on	Orthosteric Ligand	class-b1_on class-b2_on
13.79	Consensus	class-b1_class-b2_cons_on_gp	Orthosteric Ligand	class-b1_on_gp class-b2_on_gp
13.79	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
13.79	Consensus	mc3_on_gp	Orthosteric Ligand	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
13.79	Consensus	nmur2_on	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
13.79	Consensus	nmur2_on_gp	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/β1/γ2
13.64	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
13.64	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
13.64	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
13.64	Single	6IIV	Daltroban	6IIV-TXA2-Daltroban
13.64	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/β1/γ2
13.64	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
13.64	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/β1/γ2
13.64	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
13.64	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
13.64	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
13.64	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
13.64	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
13.64	Single	8EJK	TAK-875	8EJK-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.64	Single	8KEX	DCA-3P	8KEX-MRGPRX4-DCA-3P
13.64	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/β1/γ2
13.64	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-α-chim(NtGi2-Gs-CtGq)/β1/γ2
13.64	Consensus	cck_off	Orthosteric Ligand	ccka_off
13.64	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
13.64	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
13.64	Consensus	gal1_on_gp	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
13.64	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/β1/γ2
13.51	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/β1/γ2
13.51	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/β1/γ2
13.51	Single	9JR3	PTH	9JR3-PTH1-PTH-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.51	Consensus	glucagon_on	Orthosteric Ligand	glp_on gluc_on secretin_on gip_on
13.33	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
13.33	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/β1/γ2
13.33	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
13.33	Single	8IED	A1LYA	8IED-GPR156-A1LYA-Go/β1/γ2
13.33	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/β1/γ2
13.33	Single	8YW4	Retatrutide	8YW4-GIP-Retatrutide-chim(NtGi1-Gs)/β1/γ2
13.33	Single	9BUD	Cagrilintide	9BUD-CT-Cagrilintide-Gs/β1/γ2
13.33	Single	9EBO	GLP-1 (ACPC18)	9EBO-GLP-1-GLP-1 (ACPC18)-Gs/β1/γ2
13.33	Consensus	neuromedin-u_on	Orthosteric Ligand	nmur1_on nmur2_on
13.33	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on nk3_on
13.16	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
13.04	Single	4PHU	Fasiglifam	4PHU-FFA1-Fasiglifam
13.04	Single	5T1A	BMS-681	5T1A-CCR2-BMS-681-PubChem 12093170
13.04	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
13.04	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
13.04	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/β1/γ2
13.04	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/β1/γ2
13.04	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
13.04	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/β1/γ2
13.04	Single	8EJC	TAK-875	8EJC-FFA1-TAK-875-chim(NtGi1L-Gs-CtGq)/β1/γ2
13.04	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/β1/γ2
13.04	Single	8WGB	VU0155041	8WGB-mGlu4; mGlu2-Glutammate-VU0155041-Gi3/β1/γ2
13.04	Single	8X0B	VU0424465	8X0B-mGlu5; mGlu5-Quisqualate-VU0424465
13.04	Single	8ZVZ	BW245C	8ZVZ-DP₁-BW245C-Gs/β1/γ2
13.04	Single	9B9Z	A1AKO	9B9Z-CB₁-A1AKO
13.04	Single	9HC0	4YI	9HC0-mGlu₅-4YI
13.04	Single	9KPF	SA0	9KPF-TAS2R16-SA0-Gi1/β1/γ2
13.04	Consensus	cxcr2_on_gp	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
13.04	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off cyslt1_off
13.04	Consensus	lpa1_on	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
13.04	Consensus	lpa1_on_gp	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
13.04	Consensus	s1p5_off	Orthosteric Ligand	7YXA-S1P₅-ONO-5430608
12.90	Single	8XVI	Endothelin-1	8XVI-ET_A-Endothelin-1-chim(Gs-CtGq)/β1/γ2
12.90	Consensus	calcitonin_on	Orthosteric Ligand	ctlike_on
12.90	Consensus	neuromedin-u_on_gp	Orthosteric Ligand	nmur1_on_gp nmur2_on_gp
12.90	Consensus	vpac_on	Orthosteric Ligand	vpac1_on vpac2_on
12.50	Single	5TZR	MK8666	5TZR-FFA1-MK8666
12.50	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
12.50	Single	6NBI	Long-Acting PTH Analog	6NBI-PTH1-Long-Acting PTH Analog-Gs/β1/γ2
12.50	Single	6OS1	TRV026	6OS1-AT₁-TRV026
12.50	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/β1/γ2
12.50	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/β1/γ2
12.50	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
12.50	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/β1/γ2
12.50	Single	7P2L	4YI	7P2L-mGlu₅-4YI
12.50	Single	7R0C	AVP	7R0C-V₂-AVP-Arrestin2
12.50	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/β1/γ2
12.50	Single	7T9N	DPPC	7T9N-TSH-M22 Fab-DPPC-Gs/β1/γ2
12.50	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/β1/γ2
12.50	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/β1/γ2
12.50	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/β1/γ2
12.50	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/β1/γ2
12.50	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/β1/γ2
12.50	Single	8JBG	Neurokinin-B	8JBG-NK₃-Neurokinin-B-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
12.50	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
12.50	Single	8ZW0	PGD2	8ZW0-DP₁-PGD2-Gs/β1/γ2
12.50	Single	9BLB	Cagrilintide backbone (non-acylated)	9BLB-CT-Cagrilintide backbone (non-acylated)-Gs/β1/γ2
12.50	Single	9BP3	Cagrilintide	9BP3-CT (AMY1)-Cagrilintide-Gs/β1/γ2; RAMP1
12.50	Single	9CLW	TUG-1375	9CLW-FFA2-TUG-1375-4-CMTB-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.50	Single	9ITE	LPA	9ITE-LPA₆-LPA-chim(NtGi2-G13)/β1/γ2
12.50	Single	9IZG	NKP	9IZG-LPA₁-NKP-chim(NtGi1-Gs-CtGq)/β1/γ2
12.50	Single	9J1P	g1:Ox	9J1P-GLP-1-g1:Ox-chim(NtGi1-Gs)/β1/γ2
12.50	Consensus	calcitonin_on_gp	Orthosteric Ligand	ctlike_on_gp
12.50	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-6P4-CCL5-Gi1/β1/γ1 7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
12.50	Consensus	ffa2_on	Orthosteric Ligand	8J22-FFA2-TUG-1375-Gi1/β1/γ2
12.50	Consensus	ffa_on	Orthosteric Ligand	ffa2_on ffa3_on
12.50	Consensus	ffa_on_gp	Orthosteric Ligand	ffa2_on_gp ffa3_on_gp
12.50	Consensus	gi_ffa	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/β1/γ2 8J22-FFA2-TUG-1375-Gi1/β1/γ2
12.50	Consensus	gi_lpa	Orthosteric Ligand	7TD1-LPA₁-LPA-Gi1/β1/γ2 7YU3-LPA₁-ONO-0740556-Gi1/β1/γ2
12.50	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
12.50	Consensus	lpa_on_gp	Orthosteric Ligand	lpa1_on_gp
12.50	Consensus	vpac_on_gp	Orthosteric Ligand	vpac1_on_gp vpac2_on_gp
12.20	Single	8F0J	Pramlintide Analogue San45	8F0J-CT-Pramlintide Analogue San45-Gs/β1/γ2
12.12	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/β1/γ2; RAMP3
12.12	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/β1/γ2
12.12	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/β1/γ2
12.12	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/β1/γ2
12.12	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/β1/γ2
12.12	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/β1/γ2
12.12	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/β1/γ2
12.00	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
12.00	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
12.00	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
12.00	Single	6IIU	Ramatroban	6IIU-TXA2-Ramatroban
12.00	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/β1/γ2
12.00	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
12.00	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/β1/γ2
12.00	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/β1/γ2
12.00	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/β1/γ2
12.00	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/β1/γ2
12.00	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/β1/γ2
12.00	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/β1/γ2
12.00	Single	8JPC	Neurotensin-(8-13)	8JPC-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
12.00	Single	8Y6W	TUG-1375	8Y6W-FFA2-TUG-1375-4-CMTB-Gi1/β1/γ2
12.00	Single	9AU0	BW245C	9AU0-DP₁-BW245C-Gs/β1/γ2
12.00	Single	9CM3	TUG-1375	9CM3-FFA2-TUG-1375-Compound 187-chim(NtGi1L-Gs-CtGq)/β1/γ2
12.00	Consensus	cxcr_on	Orthosteric Ligand	cxcr3_on cxcr4_on cxcr1_on cxcr2_on
11.90	Single	8F2B	Pramlintide Analogue San45	8F2B-CT (AMY3)-Pramlintide Analogue San45-Gs/β1/γ2; RAMP3
11.76	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/β1/γ2
11.76	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/β1/γ2; RAMP3
11.76	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/β1/γ2
11.76	Single	7V68	LY2119620	7V68-M₄-Iperoxo-LY2119620-Gi1/β1/γ2
11.76	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/β1/γ2
11.76	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/β1/γ2
11.76	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/β1/γ2
11.76	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/β1/γ2
11.76	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/β1/γ2
11.76	Consensus	ctlike_on_gp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
11.54	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
11.54	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
11.54	Single	7P00	Substance-P	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/β1/γ2
11.54	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/β1/γ2
11.54	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/β1/γ2
11.54	Single	8K4O	CXCL1	8K4O-KSHV-CXCL1-Gi1/β1/γ1
11.54	Single	8ZPL	HF51116	8ZPL-CXCR4-HF51116
11.54	Single	9GG5	U46619	9GG5-TXA2-U46619-chim(NtGi2L-Gs-CtGq)/β1/γ2
11.54	Consensus	nk1_on	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.54	Consensus	nk1_on_gp	Orthosteric Ligand	7P00-NK₁-Substance-P-chim(NtGi1-Gs-CtGq)/β1/γ2
11.43	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/β1/γ2; RAMP2
11.11	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/β1/γ2
11.11	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/β1/γ2
11.11	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/β1/γ2
11.11	Single	8XX6	CXCL8	8XX6-CXCR2-CXCL8-Go/β1/γ2
11.11	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT (AMY1)-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
11.11	Single	9C2F	Ca; Ca; Tryptophan; '54149; PO4	9C2F-CaS-Ca-Ca; Ca; Tryptophan; '54149; PO4
11.11	Single	9CM7	TUG-1375	9CM7-FFA2-TUG-1375-AZ-1729-Gi1/β1/γ2
11.11	Single	9ITB	LPA	9ITB-LPA₆-LPA-chim(NtGi1-Gs-CtGq)/β1/γ2
11.11	Single	9NS9	TUG-1375	9NS9-FFA2-TUG-1375-Compound 187-Gi1/β1/γ2
10.81	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/β1/γ2
10.81	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/β1/γ2
10.71	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/β1/γ1
10.71	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.71	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
10.71	Single	8IEI	A1LYA	8IEI-GPR156-A1LYA
10.71	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
10.71	Single	8IEP	A1LYA	8IEP-GPR156-A1LYA
10.71	Single	8INR	Alpha-MSH	8INR-MC₅-α-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.71	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/β1/γ2
10.71	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/β1/γ2
10.71	Single	8XWN	CXCL8	8XWN-CXCR2-CXCL8
10.71	Single	9J0I	UDP-Glucuronic acid	9J0I-P2Y₁₄-UDP-Glucuronic acid-Gi1/β1/γ2
10.71	Consensus	ccr1_on	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.71	Consensus	ccr1_on_gp	Orthosteric Ligand	7VLA-CCR1-CCL15(27-92)-Gi1/β1/γ2
10.53	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
10.53	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/β1/γ2
10.53	Single	8F76	Propanoic acid	8F76-OR51E2-Propanoic acid-Gs/β1/γ2
10.53	Single	8JEF	(3S)-3-hydroxyoctanoic acid	8JEF-HCA₃-(3S)-3-hydroxyoctanoic acid-Gi1/β1/γ2
10.53	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/β1/γ2
10.53	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
10.34	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/β1/γ2
10.34	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/β1/γ2
10.34	Single	8IEB	A1LYA	8IEB-GPR156-A1LYA
10.34	Single	8IOC	Gamma-MSH	8IOC-MC₃-γ-MSH-Ca-chim(NtGi1-Gs)/β1/γ2
10.00	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
10.00	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/β1/γ2
10.00	Single	7T96	LY2119620	7T96-M₂-Acetylcholine-LY2119620-Go/β1/γ2
10.00	Single	7XP6	Strychnine	7XP6-TAS2R46-Strychnine-chim(Gs-CtGt3)/β1/γ2
10.00	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab
10.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/β1/γ2
10.00	Single	8ZX5	AM251	8ZX5-GPR55-AM251-chim(NtGi1-G13)/β1/γ2
10.00	Single	9C1P	Ca; Tryptophan; '6218; PO4	9C1P-CaS-Ca-Ca; Tryptophan; '6218; PO4
10.00	Single	9IVM	GLP-1 (Truncated)	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
9.68	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/β1/γ2
9.52	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
9.52	Single	5U09	Taranabant	5U09-CB₁-Taranabant
9.52	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
9.52	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
9.52	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
9.52	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
9.52	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/β1/γ2
9.52	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/β1/γ2
9.52	Single	8HMP	C17	8HMP-GPR52-C17-Gs/β1/γ2
9.52	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
9.38	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
9.38	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/β1/γ2; RAMP1
9.38	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/β1/γ2
9.09	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
9.09	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/β1/γ2
9.09	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/β1/γ2
9.09	Single	8IYX	YL-365	8IYX-GPR34-YL-365
9.09	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
9.09	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/β1/γ2
9.09	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/β1/γ2
9.09	Single	9BUB	Cagrilintide	9BUB-CT-Cagrilintide-Gs/β1/γ2
9.09	Single	9DQJ	EP-3945	9DQJ-MRGPRD-EP-3945-chim(NtGi1-Gs-CtGq)/β1/γ2
9.09	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/β1/γ2; RAMP1
9.09	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/β1/γ2
9.09	Consensus	cxcr3_off	Orthosteric Ligand	8K2W-CXCR3-AMG487
9.09	Consensus	grh_off	Orthosteric Ligand	gnrh1_off
8.82	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
8.70	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
8.70	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/β1/γ2
8.70	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
8.70	Single	8X9T	AP503	8X9T-ADGRD1-AP503-chim(NtGi1-Gs)/β1/γ2
8.70	Single	8XBG	S3E-LysoPS	8XBG-GPR34-S3E-LysoPS
8.70	Single	8ZYY	Neurotensin peptide 8-13	8ZYY-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
8.57	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/β1/γ2
8.57	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/β1/γ2
8.57	Single	9BTW	Cagrilintide	9BTW-CT (AMY3)-Cagrilintide-Gs/β1/γ2; RAMP3
8.33	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-LSN3556672-chim(NtGi1-Gs)/β1/γ2
8.33	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
8.33	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
8.33	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
8.33	Single	9DQH	EP-2825	9DQH-MRGPRD-EP-2825-chim(NtGi1-Gs-CtGq)/β1/γ2
8.33	Single	9EAH	Nanobody AT209	9EAH-AT₁-Olmesartan-Nanobody AT209
8.33	Consensus	adgrg2_on	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
8.33	Consensus	adgrg2_on_gp	Orthosteric Ligand	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/β1/γ2 7WUQ-ADGRG2-Gs/β1/γ2 7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
8.11	Single	8F2A	Pramlintide Analogue San385	8F2A-CT (AMY3)-Pramlintide Analogue San385-Gs/β1/γ2; RAMP3
8.00	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
8.00	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
8.00	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/β1/γ1
8.00	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/β1/γ1
8.00	Single	8FMZ	Neurotensin/Neuromedin-N	8FMZ-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi2L-Gs-CtGq)/β1/γ2
8.00	Single	8FN1	Neurotensin/Neuromedin-N	8FN1-NTS₁-Neurotensin/Neuromedin-N-chim(NtGi1-Go)/β1/γ2
8.00	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
8.00	Consensus	neurotensin_on	Orthosteric Ligand	nts1_on
8.00	Consensus	nts1_on	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
8.00	Consensus	p2y12_on	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
7.69	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
7.69	Single	4GRV	Neurotensin-(8-13)	4GRV-NTS₁-Neurotensin-(8-13)
7.69	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
7.69	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
7.69	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/β1/γ2
7.69	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
7.69	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/β1/γ2
7.69	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/β1/γ2
7.69	Single	8XQS	Cholesterol	8XQS-TAS2R14-Cholesterol-Flufenamic acid-Gi1/β1/γ1
7.69	Consensus	gi_neurotensin	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Consensus	gi_p2y	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
7.69	Consensus	neurotensin_on_gp	Orthosteric Ligand	nts1_on_gp
7.69	Consensus	nts1_on_gp	Orthosteric Ligand	6OSA-NTS₁-JMV449-Gi1/β1/γ2 7L0S-NTS₁-Neurotensin-Gi1/β1/γ1
7.69	Consensus	p2y12_on_gp	Orthosteric Ligand	7XXI-P2Y₁₂-2MeSADP-Gi2/β1/γ2
7.41	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/β1/γ2
7.41	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
7.41	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/β1/γ2
7.41	Single	8FN0	Neurotensin/Neuromedin-N	8FN0-NTS₁-Neurotensin/Neuromedin-N-SBI-553-chim(NtGi1-Go)/β1/γ2
7.41	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-SBI-553
7.41	Single	8XBE	S3E-LysoPS	8XBE-GPR34-S3E-LysoPS-Gi1/β1/γ1
7.41	Single	8XVU	CXCL2	8XVU-CXCR2-CXCL2
7.41	Single	8XXH	CXCL2	8XXH-CXCR2-CXCL2-Go/β1/γ2
7.41	Single	9JH5	C16:0 Ceramide	9JH5-CysLT₂-C16:0 Ceramide-chim(NtGi1-Gs-CtGq)/β1/γ2
7.14	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
7.14	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/β1/γ2
7.14	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/β1/γ2
7.14	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/β1/γ2
7.14	Single	8SAI	1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine	8SAI-GPR34-1-Oleoyl-2-Hydroxy-Sn-Glycero-3-Phospho-L-Serine-Gi1/β1/γ2
7.14	Single	8XQJ	JN241	8XQJ-Apelin-JN241
6.90	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/β1/γ2
6.90	Single	9BUE	Cagrilintide	9BUE-CT-Cagrilintide-Gs/β1/γ2
6.67	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/β1/γ2
6.45	Single	9B5Y	Long-Acting PTH	9B5Y-PTH1-Long-Acting PTH-chim(NtGi1-Gq)/β1/γ2
6.25	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/β1/γ2
6.06	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/β1/γ2; RAMP2
5.71	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/β1/γ2
5.56	Single	7XKE	Beta-Hydroxyandrosterone	7XKE-ADGRG2-β-Hydroxyandrosterone-chim(NtGi1-Gs)/β1/γ2
5.56	Single	9BQ3	Cagrilintide	9BQ3-CT (AMY2)-Cagrilintide-Gs/β1/γ2; RAMP2
5.26	Single	9IVM	LSN3318839	9IVM-GLP-1-GLP-1 (Truncated)-LSN3318839-chim(NtGi1-Gs)/β2/γ2
5.26	Consensus	p2y_off	Orthosteric Ligand	p2y1_off
5.00	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
5.00	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
5.00	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/β1/γ2
5.00	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/β1/γ2
5.00	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
5.00	Single	8RQL	Flufenamic acid	8RQL-TAS2R14-Flufenamic acid-Flufenamic acid-chim(NtGi1-Gt3)/β1/γ2
5.00	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
4.76	Single	6LI0	C17	6LI0-GPR52-C17
4.76	Single	7XKF	Beta-Hydroxyandrosterone	7XKF-ADGRG2-β-Hydroxyandrosterone-Gs/β1/γ2
4.76	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/β1/γ2
4.76	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; Spermine
4.76	Single	8YKD	Dehydroepiandrosterone	8YKD-ADGRG2-Dehydroepiandrosterone-chim(NtGi1-Gs)/β1/γ2
4.76	Single	8ZYU	Neurotensin peptide 8-13	8ZYU-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
4.76	Single	9E7R	GB88	9E7R-PAR2-GB88-chim(NtGi1L-Gs-CtGq)/β1/γ2
4.76	Single	9JCP	LPC	9JCP-GPR4-LPC-chim(NtGi1-Gs-CtGq)/β1/γ2
4.55	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/β1/γ2
4.55	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/β1/γ2
4.55	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
4.55	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
4.55	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/β1/γ2
4.55	Single	8T3V	Docosa-4,7,10,13,16,19-Hexaenoic acid	8T3V-FFA1-Docosa-4,7,10,13,16,19-Hexaenoic acid-chim(NtGi2L-Gs-CtGq)/β1/γ2
4.55	Single	8XXX	CXCL6	8XXX-CXCR2-CXCL6-Go/β1/γ2
4.55	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
4.55	Consensus	ccr6_on_gp	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/β1/γ2
4.55	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.35	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
4.35	Single	7UTZ	DPPC	7UTZ-TSH-TR1402-DPPC-Gs/β1/γ2
4.35	Single	8JD6	VU0364770	8JD6-mGlu4; mGlu4-Phosphoserine-VU0364770-Gi3/β1/γ2
4.35	Single	8YRG	Fospropofol	8YRG-MRGPRX4-Fospropofol-chim(NtGi1-Gs-CtGq)/β1/γ2
4.17	Single	4QIM	ANTA XV	4QIM-SMO-ANTA XV
4.17	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
4.17	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
4.17	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/β1/γ2
4.17	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.17	Single	8TH3	AT118-H Nanobody	8TH3-AT₁-AT118-H Nanobody
4.17	Single	9IVG	GLP-1 (Truncated)	9IVG-GLP-1-GLP-1 (Truncated)-chim(NtGi1-Gs)/β1/γ2
4.17	Consensus	cxcr1_on_gp	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/β1/γ2
4.00	Single	4JKV	Taladegib	4JKV-SMO-Taladegib
4.00	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.00	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.00	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
4.00	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
4.00	Single	8TH4	AT118-L Nanobody	8TH4-AT₁-Losartan-AT118-L Nanobody
4.00	Single	8XQP	Cholesterol	8XQP-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
4.00	Single	8ZYT	Neurotensin peptide 8-13	8ZYT-NTS₁-Neurotensin peptide 8-13-SBI-553-Arrestin2
3.85	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
3.85	Single	5V56	TC114	5V56-SMO-TC114
3.85	Single	5V57	TC114	5V57-SMO-TC114
3.85	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/β1/γ2
3.85	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
3.85	Single	8JD5	JNJ-40411813; ADX88178	8JD5-mGlu2; mGlu4-Glutamate-JNJ-40411813; ADX88178-Gi1/β1/γ2
3.85	Single	8XQT	Cholesterol	8XQT-TAS2R14-Cholesterol-Gi1/β1/γ1
3.85	Single	8XX7	CXCL5	8XX7-CXCR2-CXCL5-Go/β1/γ2
3.70	Single	8JPB	Neurotensin-(8-13)	8JPB-NTS₁-Neurotensin-(8-13)-SBI-553; GDP; Mg-Gq; GRK2
3.70	Single	8XQJ	JN241	8XQJ-Apelin-JN241
3.70	Single	8XQN	Cholesterol	8XQN-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
3.70	Single	8XWA	CXCL1	8XWA-CXCR2-CXCL1
3.70	Single	8XWM	CXCL6	8XWM-CXCR2-CXCL6
3.70	Single	8XWS	CXCL5	8XWS-CXCR2-CXCL5
3.70	Single	8XX3	CXCL3	8XX3-CXCR2-CXCL3-Go/β1/γ2
3.57	Single	8XWF	CXCL3	8XWF-CXCR2-CXCL3
3.57	Single	8XWV	CXCL1	8XWV-CXCR2-CXCL1-Go/β1/γ2
3.45	Single	5TZY	MK8666; AP8	5TZY-FFA1-MK8666; AP8
3.45	Single	8XQL	Cholesterol	8XQL-TAS2R14-Cholesterol-Aristolochic acid A-Gt3/β1/γ1
3.45	Single	8XQO	Cholesterol	8XQO-TAS2R14-Cholesterol-Aristolochic acid A-Gi1/β1/γ1
3.33	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/β1/γ2

Consensus Members
	Id	Members
	8FYT	8FYT-5-HT_1A-LSD-Gi1/β1/γ1
	8FYX	8FYX-5-HT_1A-Buspirone-Gi1/β1/γ1
	8JSP	8JSP-5-HT_1A-Ulotaront-Gi1/β1/γ2
	8JT6	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/β1/γ2
	7E2Y	7E2Y-5-HT_1A-Serotonin-Gi1/β1/γ2
	7E2Z	7E2Z-5-HT_1A-Aripiprazole-Gi1/β1/γ2
	8FY8	8FY8-5-HT_1A-5-MeO-DMT-Gi1/β1/γ1
	8FYE	8FYE-5-HT_1A-4-F,5-MeO-PyrT-Gi1/β1/γ1
	8FYL	8FYL-5-HT_1A-Vilazodone-Gi1/β1/γ1

Net Summary
I_min	2.85889
Number of Linked Nodes	907
Number of Links	1106
Number of Hubs	176
Number of Links mediated by Hubs	655
Number of Communities	29
Number of Nodes involved in Communities	239
Number of Links involved in Communities	347

Path Summary
Number Of Nodes in MetaPath	111
Number Of Links MetaPath	110
Number of Shortest Paths	9969747
Length Of Smallest Path	3
Average Path Length	50.7629
Length of Longest Path	75
Minimum Path Strength	0.533889
Average Path Strength	5.71492
Maximum Path Strength	21.6661
Minimum Path Correlation	0.7
Average Path Correlation	0.99157
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.42857
Average % Of Corr. Nodes	23.5027
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	58.9274
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	5ht1_on_gp	5ht1a_on_gp 5ht1d_on_gp 5ht1e_on_gp 5ht1f_on_gp

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Download 5ht1a_on_gp.zip

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