psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	1x35	1x39	2.8705	No	Yes	0	6	7
2	1x35	7x35	4.83327	No	No	0	6	4
3	1x38	7x39	2.98066	No	No	0	5	6
4	1x39	2x57	4.5996	Yes	Yes	2	7	7
5	1x39	2x61	3.20029	Yes	No	0	7	6
6	1x39	7x38	2.94538	Yes	Yes	2	7	5
7	1x42	7x47	2.73639	No	No	0	7	8
8	1x43	1x47	4.62271	No	No	0	6	6
9	1x43	2x57	6.5706	No	Yes	2	6	7
10	1x43	2x58	3.75546	No	No	2	6	8
11	1x50	2x50	7.51339	No	Yes	0	9	9
12	1x50	2x51	5.20808	No	No	0	9	7
13	1x50	7x50	6.04881	No	No	0	9	9
14	1x53	2x47	3.02444	No	No	0	9	9
15	1x53	7x54	3.29962	No	Yes	0	9	6
16	1x55	1x59	2.83812	No	No	0	4	5
17	1x56	8x50	3.87289	No	Yes	0	7	8
18	1x57	2x44	3.72477	No	No	0	7	6
19	1x59	1x60	3.00085	No	Yes	0	5	4
20	2x37	2x40	5.78768	No	Yes	0	7	8
21	2x38	I2x57	4.43622	No	No	0	5	7
22	2x38	4x42	3.33327	No	No	0	5	7
23	2x41	4x43	3.75006	No	No	0	5	2
24	2x42	3x45	3.59009	Yes	No	0	7	7
25	2x42	3x46	3.90235	Yes	Yes	0	7	9
26	2x42	3x49	5.94523	Yes	No	0	7	8
27	2x42	4x42	2.73704	Yes	No	0	7	7
28	2x42	4x46	3.39156	Yes	Yes	0	7	7
29	2x43	3x46	2.84464	No	Yes	6	8	9
30	2x45	4x46	7.14613	No	Yes	0	9	7
31	2x45	4x50	4.63068	No	No	0	9	9
32	2x46	2x50	4.08905	Yes	Yes	6	9	9
33	2x46	3x42	4.75677	Yes	No	0	9	8
34	2x46	3x43	3.51158	Yes	Yes	6	9	8
35	2x46	7x49	4.28572	Yes	Yes	6	9	9
36	2x50	3x39	4.09378	Yes	No	0	9	9
37	2x50	7x46	6.00029	Yes	No	0	9	9
38	2x50	7x49	4.47171	Yes	Yes	6	9	9
39	2x52	3x35	5.92132	No	No	0	7	8
40	2x53	3x35	4.84228	No	No	0	7	8
41	2x56	3x32	4.60584	No	No	0	6	5
42	2x57	2x58	3.16882	Yes	No	2	7	8
43	2x57	7x42	8.36232	Yes	Yes	2	7	7
44	2x59	E1x52	3.54693	No	Yes	0	6	6
45	2x59	3x28	7.18002	No	No	0	6	5
46	2x60	7x38	3.37032	No	Yes	2	6	5
47	2x60	7x42	3.71458	No	Yes	2	6	7
48	2x63	E1x50	4.80855	No	Yes	2	4	8
49	2x64	7x35	3.95185	No	No	0	5	4
50	E1x49	E2	5.82602	No	Yes	2	5	3
51	E1x50	E1x52	10.9251	Yes	Yes	0	8	6
52	3x25	E1x50	6.40138	No	Yes	2	9	8
53	E1x50	E2	3.14279	Yes	Yes	2	8	3
54	E1x50	E2x50	8.41547	Yes	No	2	8	9
55	E1x51	E1x52	3.49799	No	Yes	0	3	6
56	3x24	E1x52	5.32527	No	Yes	0	5	6
57	3x22	3x26	3.33053	No	No	0	3	6
58	3x22	E2	5.03455	No	Yes	2	3	3
59	3x25	E2x50	6.89	No	No	2	9	9
60	3x32	Lig	6.42477	No	Yes	2	5	0
61	3x33	Lig	5.70603	Yes	Yes	2	4	0
62	3x34	4x54	2.79976	No	No	0	5	4
63	3x34	4x57	3.81223	No	No	0	5	6
64	3x36	6x48	4.8784	No	Yes	0	7	8
65	3x36	Lig	3.51356	No	Yes	2	7	0
66	3x37	4x56	6.45992	Yes	No	0	6	5
67	3x37	5x46	4.47793	Yes	No	0	6	4
68	3x38	4x50	9.93438	No	No	0	7	9
69	3x38	4x53	3.05384	No	No	0	7	8
70	3x40	5x50	3.43588	No	No	0	7	8
71	3x40	6x48	3.05744	No	Yes	0	7	8
72	3x41	4x49	3.8246	No	No	0	5	7
73	3x43	6x44	3.30674	Yes	No	0	8	9
74	3x43	7x49	3.0329	Yes	Yes	6	8	9
75	3x43	7x53	4.63984	Yes	Yes	6	8	9
76	3x44	5x50	2.9051	No	No	0	7	8
77	3x46	3x50	5.73523	Yes	Yes	6	9	9
78	3x46	7x53	3.43062	Yes	Yes	6	9	9
79	3x47	5x54	5.90341	No	No	6	9	8
80	3x47	5x58	6.67238	No	Yes	6	9	9
81	3x48	5x57	2.75077	No	No	0	6	8
82	3x49	I2x57	5.76048	No	No	0	8	7
83	3x50	5x58	6.45367	Yes	Yes	6	9	9
84	3x50	7x53	4.82122	Yes	Yes	6	9	9
85	3x50	G.H5.23	4.18206	Yes	No	0	9	4
86	3x50	G.H5.25	6.55707	Yes	No	0	9	7
87	3x51	3x55	6.99398	No	No	0	8	7
88	3x51	5x57	7.66407	No	No	0	8	8
89	3x51	5x60	6.64112	No	No	0	8	5
90	3x53	G.H5.19	3.71007	No	Yes	0	8	8
91	3x54	5x61	5.9042	No	No	0	8	8
92	3x54	G.H5.20	3.84277	No	Yes	0	8	9
93	3x55	3x56	2.93266	No	No	0	7	6
94	3x55	5x64	4.72193	No	No	0	7	5
95	3x56	I2x52	4.11243	No	No	0	6	4
96	G.H5.16	I2x50	4.12116	No	No	0	6	8
97	G.S3.01	I2x51	3.07703	Yes	No	0	4	6
98	G.hns1.03	I2x55	3.2411	No	No	0	4	5
99	4x38	4x41	3.35829	No	No	0	7	4
100	E2	E2	61.46	Yes	Yes	2	3	3
101	E2	E2x51	11.9393	Yes	No	2	3	4
102	E2	E2x52	3.11788	Yes	No	2	3	4
103	5x32	E2	2.87557	No	Yes	2	3	3
104	5x35	E2	4.37582	No	Yes	2	1	3
105	5x36	E2	7.73164	No	Yes	2	4	3
106	5x40	6x59	4.88784	No	No	0	4	4
107	5x42	5x46	3.37817	No	No	0	5	4
108	5x43	Lig	4.89137	No	Yes	2	5	0
109	5x44	5x47	2.81735	Yes	Yes	2	6	8
110	5x44	5x48	3.2943	Yes	No	0	6	4
111	5x44	6x52	5.00462	Yes	Yes	2	6	7
112	5x44	6x56	4.02929	Yes	No	0	6	5
113	5x47	5x51	2.81729	Yes	No	0	8	6
114	5x47	6x49	6.68629	Yes	Yes	0	8	5
115	5x47	6x52	10.5241	Yes	Yes	2	8	7
116	5x49	5x50	3.67131	No	No	0	5	8
117	5x51	6x44	3.43088	No	No	0	6	9
118	5x54	5x58	3.13291	No	Yes	6	8	9
119	5x56	5x60	2.93962	No	No	0	4	5
120	5x58	6x37	9.69578	Yes	No	0	9	8
121	5x58	6x40	3.08259	Yes	No	0	9	8
122	5x62	6x34	3.18369	No	No	0	5	6
123	5x65	6x30	3.52316	No	No	0	8	6
124	6x26	G.h4s6.12	2.74846	No	Yes	0	3	4
125	6x29	G.H5.26	4.33239	No	Yes	0	5	5
126	6x33	G.H5.25	3.0845	No	No	0	8	7
127	6x36	7x56	3.91768	No	No	0	8	7
128	6x40	7x52	3.65175	No	No	0	8	8
129	6x40	7x53	5.28088	No	Yes	0	8	9
130	6x44	6x48	7.35863	No	Yes	0	9	8
131	6x45	6x49	3.16799	No	Yes	0	6	5
132	6x47	7x45	6.12185	No	No	0	9	9
133	6x48	6x52	3.61464	Yes	Yes	0	8	7
134	6x48	7x41	5.58722	Yes	No	0	8	7
135	6x48	7x45	7.87922	Yes	No	0	8	9
136	6x49	6x50	3.1333	Yes	No	0	5	9
137	6x50	7x37	2.7861	No	No	0	9	6
138	6x50	7x40	3.50568	No	No	0	9	8
139	6x51	6x52	2.73229	No	Yes	2	6	7
140	6x51	6x55	6.41795	No	No	2	6	5
141	6x51	Lig	5.99661	No	Yes	2	6	0
142	6x54	7x33	3.08416	No	No	0	5	4
143	6x54	7x34	4.95763	No	No	0	5	4
144	6x54	7x37	3.26396	No	No	0	5	6
145	6x55	Lig	7.71228	No	Yes	2	5	0
146	6x61	E3	4.95784	No	Yes	0	2	2
147	E3	E3	10.0578	Yes	Yes	2	2	2
148	7x30	E3	3.16889	No	Yes	0	3	2
149	7x34	7x38	3.21863	No	Yes	2	4	5
150	7x34	Lig	11.2111	No	Yes	2	4	0
151	7x38	7x42	5.17011	Yes	Yes	2	5	7
152	7x38	Lig	4.07881	Yes	Yes	2	5	0
153	7x42	Lig	3.5429	Yes	Yes	2	7	0
154	7x45	7x49	5.08267	No	Yes	0	9	9
155	7x51	7x55	3.21165	No	No	0	6	6
156	7x54	8x50	5.55386	Yes	Yes	0	6	8
157	8x47	8x49	3.79769	No	No	0	8	7
158	8x47	8x50	3.79658	No	Yes	0	8	8
159	8x48	8x51	3.82598	No	No	0	5	8
160	G.HN.11	G.HN.33	3.34186	Yes	Yes	0	2	4
161	G.HN.30	G.HN.33	5.23335	No	Yes	0	7	4
162	G.HN.37	b.b5x2	3.5049	No	Yes	0	3	7
163	G.HN.39	b.b5x5	3.29148	No	Yes	0	5	5
164	G.HN.40	b.b5x2	6.86965	No	Yes	0	7	7
165	G.HN.40	b.b5x3	3.75168	No	Yes	0	7	9
166	G.HN.43	b.b5x3	6.50322	No	Yes	0	9	9
167	G.HN.44	b.b5x3	9.689	No	Yes	0	6	9
168	G.HN.47	b.b4x2	5.2733	No	Yes	0	6	8
169	G.HN.47	b.b4x4	2.99139	No	Yes	0	6	8
170	G.HN.50	b.b4x2	7.28604	No	Yes	0	5	8
171	G.S1.01	G.S3.02	5.35777	No	No	0	6	4
172	G.S1.01	G.S3.04	8.79973	No	Yes	0	6	6
173	G.S1.02	G.S3.01	2.8713	Yes	Yes	9	5	4
174	G.S1.02	G.S3.03	7.77903	Yes	Yes	9	5	7
175	G.S1.02	G.h2s4.05	5.41616	Yes	No	0	5	7
176	G.H5.11	G.S1.02	4.88491	No	Yes	9	8	5
177	G.S1.03	G.S3.06	5.93838	No	Yes	0	9	5
178	G.S1.04	G.S4.03	4.37232	No	Yes	0	7	7
179	G.S1.05	G.S1.07	5.19292	No	No	0	9	9
180	G.S1.05	G.h2s4.01	10.0587	No	Yes	0	9	9
181	G.H1.01	G.S1.06	4.29026	Yes	Yes	7	9	8
182	G.S1.06	G.S3.05	5.81113	Yes	No	0	8	7
183	G.S1.06	G.S3.07	3.83589	Yes	No	7	8	9
184	G.S1.06	G.S4.03	3.63692	Yes	Yes	7	8	7
185	G.S1.07	G.S4.04	3.24558	No	Yes	0	9	9
186	G.H3.12	G.S1.07	4.78628	No	No	0	8	9
187	G.H3.01	G.s1h1.04	3.01467	Yes	No	0	9	9
188	G.S5.07	G.s1h1.06	2.97647	Yes	No	0	9	9
189	G.H1.01	G.S3.07	7.0513	Yes	No	7	9	9
190	G.H1.04	G.S4.05	3.30478	No	No	7	7	7
191	G.H1.04	G.S5.05	3.33796	No	Yes	7	7	9
192	G.H1.07	G.H5.03	5.71536	No	No	0	9	8
193	G.H1.08	G.S2.06	8.76207	No	Yes	0	8	9
194	G.hfs2.07	b.l7x4	4.41883	No	Yes	0	9	9
195	G.S2.01	b.l7x2	3.59873	No	No	1	9	9
196	G.S2.02	G.S3.07	2.7579	No	No	0	5	9
197	G.S2.03	G.S2.05	5.37607	No	No	1	9	3
198	G.S2.03	G.S3.04	5.77582	No	Yes	1	9	6
199	G.S2.03	G.S3.06	7.18338	No	Yes	1	9	5
200	G.S2.04	G.S3.05	3.02782	No	No	0	6	7
201	G.S2.05	G.S3.04	8.16271	No	Yes	1	3	6
202	G.S2.06	G.S3.03	12.2924	Yes	Yes	0	9	7
203	G.S2.06	G.S3.05	3.69365	Yes	No	0	9	7
204	G.S2.07	G.S3.02	7.92621	No	No	0	3	4
205	G.S2.08	G.s2s3.01	11.8895	Yes	No	9	5	4
206	G.H5.04	G.S2.08	9.1363	No	Yes	0	7	5
207	G.H5.05	G.S2.08	3.98254	No	Yes	9	5	5
208	G.H5.08	G.S2.08	6.76548	Yes	Yes	9	8	5
209	G.H5.05	G.s2s3.01	3.90065	No	No	9	5	4
210	G.H5.08	G.s2s3.01	9.05948	Yes	No	9	8	4
211	G.S3.01	G.S3.03	7.13014	Yes	Yes	9	4	7
212	G.H5.08	G.S3.01	3.73245	Yes	Yes	9	8	4
213	G.H5.08	G.S3.03	2.83929	Yes	Yes	9	8	7
214	G.H5.11	G.S3.03	5.32208	No	Yes	9	8	7
215	G.S3.04	G.S3.06	6.63734	Yes	Yes	1	6	5
216	G.S3.06	G.h2s4.01	3.7326	Yes	Yes	1	5	9
217	G.S3.06	b.l5x5	14.6683	Yes	Yes	1	5	9
218	G.H2.07	G.S3.08	6.89694	Yes	No	1	9	9
219	G.S3.08	G.h2s4.01	2.78915	No	Yes	1	9	9
220	G.H2.02	G.s3h2.03	3.73173	Yes	No	1	8	9
221	G.H2.07	G.s3h2.03	6.41142	Yes	No	1	9	9
222	G.s3h2.03	b.l9x6	3.37735	No	Yes	1	9	8
223	G.H2.02	G.H2.07	3.07555	Yes	Yes	1	8	9
224	G.H2.02	b.l9x6	4.5019	Yes	Yes	1	8	8
225	G.H2.03	G.H2.05	5.8669	Yes	No	1	9	8
226	G.H2.04	G.H2.07	5.1326	Yes	Yes	0	9	9
227	G.H2.04	G.H3.08	3.65445	Yes	No	0	9	9
228	G.H2.04	G.H3.11	3.80185	Yes	No	0	9	7
229	G.H2.04	G.H3.12	3.29227	Yes	No	0	9	8
230	G.H2.06	b.l9x6	3.55727	Yes	Yes	1	9	8
231	G.H2.06	b.b14x1	9.32967	Yes	No	1	9	8
232	G.H2.06	b.l15x1	4.06379	Yes	Yes	1	9	7
233	G.H2.06	b.l17x6	8.19399	Yes	Yes	1	9	9
234	G.H2.07	G.h2s4.01	4.03394	Yes	Yes	1	9	9
235	G.H2.07	b.l7x2	3.53697	Yes	No	1	9	9
236	G.H2.07	b.l9x6	2.99681	Yes	Yes	1	9	8
237	G.H2.08	G.H3.18	4.77285	No	Yes	0	8	9
238	G.H2.09	G.H3.17	7.57065	No	Yes	1	8	5
239	G.H2.09	b.b2x1	6.32208	No	Yes	1	8	8
240	G.H2.09	b.l28x1	5.98698	No	Yes	1	8	9
241	G.H2.10	b.b2x1	5.54237	No	Yes	1	7	8
242	G.h2s4.01	b.l5x5	10.6648	Yes	Yes	1	9	9
243	G.H3.17	G.h2s4.02	9.14191	Yes	No	0	5	7
244	G.h2s4.02	b.l1x6	6.49121	No	No	0	7	9
245	G.S4.01	G.S5.03	2.75502	No	Yes	0	8	8
246	G.H3.18	G.S4.02	8.21985	Yes	Yes	17	9	8
247	G.S4.02	G.h3s5.03	3.06413	Yes	No	17	8	7
248	G.S4.02	G.S5.02	2.90252	Yes	No	0	8	6
249	G.S4.03	G.S5.03	2.8241	Yes	Yes	7	7	8
250	G.S4.03	G.S5.05	2.84592	Yes	Yes	7	7	9
251	G.H3.08	G.S4.04	5.39932	No	Yes	0	9	9
252	G.H3.09	G.S4.04	12.6592	Yes	Yes	8	9	9
253	G.S4.04	G.S5.04	2.88501	Yes	Yes	8	9	9
254	G.S4.05	G.S5.07	2.97098	No	Yes	7	7	9
255	G.H3.05	G.S4.06	4.02701	No	No	0	9	7
256	G.H4.15	G.S4.06	6.21192	Yes	No	0	8	7
257	G.S4.07	G.s4h3.03	3.87184	No	No	0	8	8
258	G.S4.07	G.s5hg.01	3.03875	No	No	0	8	9
259	G.S5.06	G.s4h3.01	7.88823	No	No	0	8	7
260	G.HG.04	G.s4h3.01	10.177	Yes	No	0	9	7
261	G.H4.11	G.s4h3.01	3.36393	No	No	0	7	7
262	G.s4h3.02	G.s5hg.01	4.59981	No	No	0	9	9
263	G.HG.03	G.s4h3.02	4.74139	No	No	0	6	9
264	G.HG.07	G.s4h3.02	4.05058	No	No	0	9	9
265	G.H3.01	G.s4h3.03	8.94472	Yes	No	0	9	8
266	G.s4h3.04	G.s4h3.05	11.642	Yes	Yes	13	8	9
267	G.HG.04	G.s4h3.04	4.6322	Yes	Yes	0	9	8
268	G.HG.07	G.s4h3.04	6.46253	No	Yes	13	9	8
269	G.HG.15	G.s4h3.04	2.87471	No	Yes	0	7	8
270	G.hgh4.01	G.s4h3.04	3.78755	No	Yes	0	6	8
271	G.HG.07	G.s4h3.05	6.8963	No	Yes	13	9	9
272	G.HG.13	G.s4h3.05	3.80517	Yes	Yes	13	7	9
273	G.H3.01	G.s4h3.06	4.56888	Yes	No	0	9	8
274	G.H3.01	G.s4h3.08	3.08495	Yes	No	0	9	8
275	G.H3.03	G.s4h3.15	5.88466	No	No	0	4	9
276	G.H3.06	G.h4s6.01	3.09755	Yes	No	0	6	4
277	G.H3.09	G.H3.13	3.52731	Yes	No	8	9	5
278	G.H3.09	G.S5.02	4.45843	Yes	No	0	9	6
279	G.H3.09	G.h4s6.01	3.94263	Yes	No	0	9	4
280	G.H3.09	G.S6.01	3.23503	Yes	No	0	9	5
281	G.H3.10	G.H3.14	6.57029	No	No	0	5	8
282	G.H3.13	G.h4s6.02	3.37517	No	Yes	8	5	8
283	G.H3.13	G.h4s6.11	4.53777	No	Yes	8	5	7
284	G.H3.14	G.h4s6.03	9.04988	No	No	0	8	5
285	G.H3.15	G.H3.17	4.42169	No	Yes	0	8	5
286	G.H3.15	G.H3.18	4.68257	No	Yes	0	8	9
287	G.H3.16	G.H3.17	12.0309	No	Yes	0	4	5
288	G.H3.17	b.l25x6	3.05037	Yes	Yes	1	5	8
289	G.H3.17	b.l28x1	3.51765	Yes	Yes	1	5	9
290	G.H3.18	G.h3s5.03	5.52043	Yes	No	17	9	7
291	G.h3s5.01	G.h3s5.02	3.253	No	No	0	3	4
292	G.h3s5.01	G.h4s6.04	3.95012	No	No	0	3	4
293	G.S5.01	G.S6.02	3.38822	No	Yes	0	7	7
294	G.H5.14	G.S5.01	5.277	No	No	0	7	7
295	G.S5.02	G.h4s6.11	3.1634	No	Yes	0	6	7
296	G.S5.03	G.S5.05	3.26165	Yes	Yes	7	8	9
297	G.H5.10	G.S5.03	3.44675	No	Yes	0	6	8
298	G.S5.04	G.S5.06	3.03065	Yes	No	0	9	8
299	G.H4.15	G.S5.04	4.06149	Yes	Yes	8	8	9
300	G.S5.04	G.S6.03	5.68409	Yes	No	8	9	5
301	G.S5.05	G.S6.04	4.39566	Yes	No	0	9	9
302	G.S5.05	G.s6h5.01	3.61146	Yes	No	7	9	9
303	G.H5.03	G.S5.05	4.54875	No	Yes	7	8	9
304	G.S5.06	G.S6.05	7.15492	No	No	0	8	4
305	G.S5.07	G.s6h5.01	6.08183	Yes	No	7	9	9
306	G.H4.03	G.HG.01	6.29981	Yes	No	0	4	5
307	G.HG.01	G.s6h5.02	3.27065	No	No	0	5	7
308	G.HG.04	G.HG.08	7.28643	Yes	No	0	9	6
309	G.H4.03	G.HG.04	2.91461	Yes	Yes	0	4	9
310	G.H4.03	G.HG.05	12.0674	Yes	No	0	4	5
311	G.HG.13	G.HG.14	3.09272	Yes	No	0	7	5
312	G.HG.14	G.HG.16	2.94806	No	No	0	5	4
313	G.HG.15	G.hgh4.02	3.16741	No	Yes	0	7	7
314	G.HG.15	G.hgh4.05	6.60285	No	Yes	0	7	7
315	G.hgh4.01	G.hgh4.02	7.58766	No	Yes	0	6	7
316	G.H4.10	G.hgh4.02	7.34031	No	Yes	18	6	7
317	G.hgh4.05	G.hgh4.07	5.31384	Yes	No	0	7	7
318	G.H4.05	G.hgh4.05	4.60144	No	Yes	0	4	7
319	G.H4.10	G.hgh4.05	17.3432	No	Yes	0	6	7
320	G.H4.02	G.hgh4.08	3.99186	No	No	19	5	3
321	G.H4.02	G.H4.05	4.33828	No	No	19	5	4
322	G.H4.07	G.S6.05	3.21936	No	No	0	5	4
323	G.H4.10	G.H4.14	10.6949	No	No	18	6	5
324	G.H4.12	G.H4.16	5.73956	Yes	No	8	5	3
325	G.H4.12	G.S6.03	13.5567	Yes	No	8	5	5
326	G.H4.12	G.S6.05	3.74489	Yes	No	0	5	4
327	G.H4.16	G.S6.03	4.57739	No	No	8	3	5
328	G.h4s6.02	G.h4s6.08	5.67234	Yes	No	0	8	3
329	G.h4s6.02	G.h4s6.11	5.65773	Yes	Yes	8	8	7
330	G.S6.01	G.h4s6.02	5.03236	No	Yes	0	5	8
331	G.h4s6.04	G.h4s6.10	2.97071	No	No	0	4	3
332	G.h4s6.09	G.h4s6.10	3.29517	No	No	0	3	3
333	G.S6.02	G.h4s6.12	11.5144	Yes	Yes	0	7	4
334	G.H5.10	G.S6.02	4.27069	No	Yes	0	6	7
335	G.H5.13	G.S6.02	6.34288	Yes	Yes	0	8	7
336	G.H5.06	G.S6.04	21.5679	No	No	0	3	9
337	G.H5.03	G.s6h5.01	6.26883	No	No	7	8	9
338	G.H5.05	G.H5.09	6.80313	No	No	0	5	4
339	G.H5.08	G.H5.12	5.34501	Yes	No	0	8	6
340	G.H5.14	G.H5.18	3.00358	No	No	0	7	4
341	G.H5.20	G.H5.25	3.49943	Yes	No	0	9	7
342	G.H5.20	G.H5.26	3.78984	Yes	Yes	0	9	5
343	G.H5.21	G.H5.26	6.67293	No	Yes	0	5	5
344	b.1x11	g.h1x11	3.43202	No	No	0	8	9
345	b.1x19	b.b21x1	3.9673	No	Yes	0	6	7
346	b.b21x2	b.lh12x1	2.79581	Yes	No	0	6	3
347	b.lh12x2	g.l1x6	9.08313	No	No	0	8	4
348	b.h2x3	b.lh12x4	6.6227	No	No	0	1	3
349	b.h2x1	b.h2x5	3.25575	Yes	Yes	0	5	5
350	b.b21x4	b.h2x1	3.57	Yes	Yes	0	5	5
351	b.b21x5	b.h2x1	6.76965	Yes	Yes	0	4	5
352	b.h2x5	b.l24x2	4.9753	Yes	Yes	0	5	6
353	b.l24x3	b.lhb1x3	2.73217	Yes	Yes	0	5	2
354	b.l24x3	b.lhb1x5	3.66744	Yes	No	0	5	1
355	b.l22x5	b.lhb1x6	5.09684	Yes	No	20	9	3
356	b.b24x7	b.lhb1x6	5.42655	No	No	20	9	3
357	b.b1x1	b.b1x3	5.89916	No	Yes	0	5	7
358	b.b1x2	b.b28x4	7.2377	No	Yes	10	3	6
359	b.b1x2	b.b28x6	8.59803	No	Yes	10	3	9
360	b.b1x3	b.b28x7	7.42886	Yes	No	3	7	9
361	b.b1x3	g.ctx16	3.21154	Yes	Yes	3	7	8
362	b.b1x4	b.b5x1	4.21464	Yes	No	0	7	5
363	b.b1x4	b.b28x5	3.38503	Yes	No	3	7	5
364	b.b1x4	g.ctx16	4.57276	Yes	Yes	3	7	8
365	b.b1x5	b.l1x1	7.92756	No	No	0	3	7
366	b.b1x6	b.b4x6	19.5158	Yes	Yes	3	9	9
367	b.b1x6	b.b5x1	3.07358	Yes	No	0	9	5
368	b.b1x6	b.b28x3	6.97726	Yes	Yes	3	9	7
369	b.b1x6	b.b28x5	2.98588	Yes	No	3	9	5
370	b.b28x2	b.l1x1	6.73276	No	No	0	4	7
371	b.l1x3	b.l1x7	10.2899	Yes	No	0	9	9
372	b.b3x4	b.l1x3	7.21097	No	Yes	3	9	9
373	b.b3x6	b.l1x3	11.6223	No	Yes	3	9	9
374	b.b4x4	b.l1x3	11.5554	Yes	Yes	3	8	9
375	b.b4x6	b.l1x3	4.41888	Yes	Yes	3	9	9
376	b.l1x5	b.l3x2	3.55185	No	Yes	0	7	9
377	b.b2x1	b.l1x6	6.10885	Yes	No	1	8	9
378	b.l1x6	b.l28x1	22.8826	No	Yes	1	9	9
379	b.b28x3	b.l1x7	2.95052	Yes	No	0	7	9
380	b.b2x1	b.l3x1	12.9437	Yes	No	1	8	9
381	b.b2x1	b.l28x1	7.98878	Yes	Yes	1	8	9
382	b.b2x3	b.b2x5	4.33801	No	Yes	3	6	7
383	b.b2x3	b.b3x2	3.97435	No	No	3	6	5
384	b.b26x2	b.b2x3	5.20923	No	No	0	7	6
385	b.b10x4	b.b2x4	12.4661	No	No	0	6	6
386	b.b2x5	b.l27x1	12.3851	Yes	No	3	7	8
387	b.b27x2	b.b2x5	4.47705	No	Yes	0	5	7
388	b.b6x5	b.l2x1	4.58601	Yes	No	0	6	5
389	b.l2x3	b.l2x5	2.83496	No	No	0	8	5
390	b.b3x1	b.l2x3	5.33209	No	No	0	5	8
391	b.l27x1	b.l2x4	6.68073	No	No	3	8	5
392	b.l27x3	b.l2x4	8.74755	No	No	3	7	5
393	b.b4x7	b.l2x5	14.3297	No	No	0	8	5
394	b.l2x5	b.l4x2	21.0944	No	No	0	5	4
395	b.b3x1	b.b6x5	4.14831	No	Yes	0	5	6
396	b.b3x2	b.b4x6	4.51565	No	Yes	3	5	9
397	b.b3x3	b.b4x3	3.36296	Yes	Yes	0	8	7
398	b.b3x3	b.b4x5	3.09676	Yes	Yes	0	8	7
399	b.b3x3	b.b6x3	3.75156	Yes	No	0	8	8
400	b.b3x3	b.b6x5	3.97274	Yes	Yes	0	8	6
401	b.b28x3	b.b3x4	4.21145	Yes	No	3	7	9
402	b.b3x5	b.l5x6	3.22422	No	No	0	9	9
403	b.b3x5	b.b6x3	2.88113	No	No	0	9	8
404	b.b3x6	b.l3x2	7.3245	No	Yes	3	9	9
405	b.l3x1	b.l5x5	6.03915	No	Yes	1	9	9
406	b.b4x2	b.l3x2	5.77038	Yes	Yes	0	8	9
407	b.b4x1	b.l5x1	3.0019	No	Yes	0	8	8
408	b.b4x2	b.b5x8	2.81531	Yes	No	0	8	5
409	b.b4x3	b.b5x7	6.00995	Yes	Yes	0	7	7
410	b.b4x3	b.l5x1	4.79339	Yes	Yes	11	7	8
411	b.b4x3	b.b7x4	4.37231	Yes	Yes	11	7	8
412	b.b4x4	b.b4x6	13.99	Yes	Yes	3	8	9
413	b.b4x4	b.b5x3	5.02768	Yes	Yes	3	8	9
414	b.b4x5	b.b5x4	3.28885	Yes	No	16	7	5
415	b.b4x5	b.b5x5	6.37549	Yes	Yes	16	7	5
416	b.b4x5	b.l8x1	3.46938	Yes	No	0	7	5
417	b.b4x6	b.b5x3	11.0951	Yes	Yes	3	9	9
418	b.b28x3	b.b4x6	3.07056	Yes	Yes	3	7	9
419	b.b4x7	b.l4x3	8.42189	No	No	0	8	6
420	b.l4x1	g.ctx16	4.30905	No	Yes	0	5	8
421	b.l4x2	g.ctx15	11.419	No	Yes	3	4	9
422	b.l4x2	g.ctx16	6.36463	No	Yes	3	4	8
423	b.b5x2	b.l4x3	10.3256	Yes	No	0	7	6
424	b.b5x4	b.b5x5	6.37212	No	Yes	16	5	5
425	b.b5x5	b.l8x8	4.58412	Yes	No	0	5	4
426	b.b5x7	b.b5x8	3.25923	Yes	No	0	7	5
427	b.b5x7	b.b8x4	7.14143	Yes	Yes	0	7	6
428	b.b5x7	b.l8x8	8.07408	Yes	No	0	7	4
429	b.l5x1	b.l5x6	3.50077	Yes	No	11	8	9
430	b.b7x4	b.l5x1	3.919	Yes	Yes	11	8	8
431	b.b8x4	b.l5x1	5.1956	Yes	Yes	11	6	8
432	b.l5x2	b.l8x10	3.89817	No	No	11	6	4
433	b.b9x3	b.l5x2	6.15683	Yes	No	11	6	6
434	b.l5x3	b.l7x3	8.80927	No	No	0	8	9
435	b.l5x5	b.l7x2	5.23625	Yes	No	1	9	9
436	b.b7x4	b.l5x6	3.2185	Yes	No	11	8	9
437	b.b6x1	b.l9x6	4.48678	No	Yes	0	9	8
438	b.b10x2	b.b6x2	2.98433	No	No	0	6	8
439	b.b10x3	b.b6x2	4.90544	No	No	0	8	8
440	b.b6x5	b.l6x4	4.9794	Yes	No	0	6	5
441	b.b10x5	b.l6x1	5.7944	Yes	No	0	9	6
442	b.l6x3	b.l6x5	7.93848	No	Yes	14	6	4
443	b.l10x3	b.l6x3	8.36148	No	No	14	6	6
444	b.b7x1	b.l6x5	5.00329	Yes	Yes	14	4	4
445	b.l6x5	b.l8x2	7.12812	Yes	No	0	4	4
446	b.l10x3	b.l6x5	3.34188	No	Yes	14	6	4
447	b.b7x1	b.b8x3	3.54983	Yes	No	0	4	6
448	b.b7x1	b.b8x5	11.4843	Yes	No	0	4	4
449	b.b7x1	b.b9x1	2.88187	Yes	No	0	4	4
450	b.b7x1	b.l10x3	5.4223	Yes	No	14	4	6
451	b.b7x2	b.l8x1	4.91846	No	No	0	8	5
452	b.b10x5	b.b7x3	3.4667	Yes	No	0	9	9
453	b.b7x4	b.b8x4	3.10463	Yes	Yes	11	8	6
454	b.l7x3	b.l7x5	6.07165	No	No	0	9	6
455	b.l7x4	b.l9x5	3.06673	Yes	No	0	9	8
456	b.b9x3	b.l7x5	4.35974	Yes	No	0	6	6
457	b.b8x1	b.b9x4	4.06258	No	No	0	8	9
458	b.b8x2	b.b8x4	6.04006	No	Yes	0	8	6
459	b.b8x2	b.b9x3	3.81508	No	Yes	0	8	6
460	b.b10x5	b.b8x3	3.52513	Yes	No	0	9	6
461	b.b8x3	b.l12x1	4.43614	No	No	0	6	6
462	b.b8x4	b.l8x10	5.73085	Yes	No	11	6	4
463	b.b8x5	b.l8x3	4.01735	No	No	0	4	3
464	b.l8x3	b.l8x9	3.7838	No	No	0	3	3
465	b.l8x5	b.l8x7	4.63768	No	No	0	3	3
466	b.l8x5	b.l8x9	3.54486	No	No	0	3	3
467	b.b9x3	b.l8x10	3.58353	Yes	No	11	6	4
468	b.b12x6	b.b9x4	16.9805	Yes	No	0	8	9
469	b.l9x3	b.l9x7	3.84556	Yes	No	1	9	7
470	b.b11x4	b.l9x3	5.37104	Yes	Yes	1	9	9
471	b.b11x6	b.l9x3	13.7425	No	Yes	1	9	9
472	b.l11x2	b.l9x3	5.90701	Yes	Yes	1	9	9
473	b.b12x4	b.l9x3	2.93256	No	Yes	1	4	9
474	b.b12x6	b.l9x3	6.00575	Yes	Yes	1	8	9
475	b.l11x2	b.l9x4	7.7593	Yes	No	0	9	5
476	b.l11x2	b.l9x5	2.99546	Yes	No	0	9	8
477	b.l11x1	b.l9x6	5.48961	No	Yes	1	9	8
478	b.l13x6	b.l9x6	7.74585	Yes	Yes	1	9	8
479	b.b14x1	b.l9x6	4.41657	No	Yes	1	8	8
480	b.b11x4	b.l9x7	3.90573	Yes	No	1	9	7
481	b.b10x1	b.b11x5	3.46997	No	No	0	9	6
482	b.b10x2	b.b10x4	5.02871	No	No	0	6	6
483	b.b10x2	b.b14x3	4.58023	No	Yes	0	6	5
484	b.b10x3	b.b11x4	3.02302	No	Yes	0	8	9
485	b.b10x4	b.b14x5	3.40305	No	No	0	6	5
486	b.b10x5	b.b11x2	8.8844	Yes	No	0	9	7
487	b.b11x1	b.l10x1	4.37921	No	Yes	0	5	3
488	b.b11x3	b.l10x1	3.09871	No	Yes	0	5	3
489	b.b14x5	b.l10x1	4.97361	No	Yes	0	5	3
490	b.l10x1	b.l14x4	3.01322	Yes	No	0	3	1
491	b.b11x1	b.l10x2	6.21364	No	No	0	5	5
492	b.b12x7	b.l10x4	5.84556	No	No	0	9	3
493	b.l10x4	b.l12x2	8.44534	No	No	0	3	6
494	b.b11x1	b.b12x5	4.9125	No	No	0	5	6
495	b.b11x3	b.b14x3	3.99698	No	Yes	5	5	5
496	b.b11x3	b.b15x1	4.39138	No	Yes	5	5	9
497	b.b11x4	b.b12x6	8.1651	Yes	Yes	1	9	8
498	b.b11x5	b.l13x7	5.1466	No	Yes	0	6	9
499	b.b11x5	b.b14x3	5.58202	No	Yes	0	6	5
500	b.b11x6	b.l11x1	3.12439	No	No	1	9	9
501	b.b11x6	b.l11x2	7.65321	No	Yes	1	9	9
502	b.l11x1	b.l13x6	4.64584	No	Yes	1	9	9
503	b.b12x2	b.l11x2	8.30323	No	Yes	0	7	9
504	b.b12x3	b.b13x7	4.08712	No	Yes	0	8	7
505	b.b12x3	b.l13x7	3.1466	No	Yes	0	8	9
506	b.b12x4	b.b12x6	4.0561	No	Yes	1	4	8
507	b.b12x4	b.b13x3	4.94104	No	No	1	4	4
508	b.b12x5	b.b13x4	2.94384	No	No	5	6	4
509	b.b12x5	b.b13x5	3.81845	No	No	5	6	4
510	b.b12x6	b.b13x3	13.7697	Yes	No	1	8	4
511	b.b12x7	b.l12x3	7.19135	No	No	0	9	5
512	b.b12x7	b.b13x4	3.81003	No	No	0	9	4
513	b.b13x2	b.l12x3	3.95488	No	No	0	4	5
514	b.b13x3	b.b13x6	6.58816	No	No	0	4	4
515	b.b13x4	b.b13x5	3.53442	No	No	5	4	4
516	b.b13x5	b.b13x7	5.60043	No	Yes	5	4	7
517	b.b13x7	b.b15x1	9.51435	Yes	Yes	5	7	9
518	b.b13x7	b.b16x6	15.1388	Yes	Yes	5	7	8
519	b.b13x7	b.b17x1	3.45092	Yes	No	0	7	4
520	b.l13x3	b.l13x7	6.01561	Yes	Yes	5	9	9
521	b.b15x3	b.l13x3	5.44229	No	Yes	5	9	9
522	b.b15x5	b.l13x3	7.76603	No	Yes	5	8	9
523	b.b16x4	b.l13x3	15.2306	Yes	Yes	5	6	9
524	b.b16x6	b.l13x3	4.83254	Yes	Yes	5	8	9
525	b.l13x4	b.l15x2	6.67014	No	Yes	0	3	9
526	b.l13x6	b.l15x1	3.084	Yes	Yes	1	9	7
527	b.b15x3	b.l13x7	2.84765	No	Yes	5	9	9
528	b.b14x1	b.l15x1	2.73907	No	Yes	1	8	7
529	b.b14x2	b.b18x3	4.99907	No	Yes	0	7	8
530	b.b14x4	b.b18x5	6.49937	No	Yes	0	8	5
531	b.b18x5	b.l14x1	5.06388	Yes	No	0	5	4
532	b.l14x3	b.l14x5	6.74328	No	No	0	5	5
533	b.l14x5	b.l16x2	6.79686	No	No	0	5	9
534	b.b16x5	b.l14x6	5.24367	Yes	No	0	5	3
535	b.b15x1	b.b16x6	10.7992	Yes	Yes	5	9	8
536	b.b15x2	b.b16x5	3.31339	Yes	Yes	0	6	5
537	b.b15x2	b.b18x3	5.06146	Yes	Yes	4	6	8
538	b.b15x2	b.b18x5	8.35178	Yes	Yes	0	6	5
539	b.b15x2	b.b19x2	9.08029	Yes	Yes	4	6	6
540	b.b15x3	b.b16x6	5.54681	No	Yes	5	9	8
541	b.b15x4	b.l17x7	3.41368	No	No	0	6	7
542	b.b15x5	b.l15x2	3.07921	No	Yes	5	8	9
543	b.l15x1	b.l17x6	8.42895	Yes	Yes	1	7	9
544	b.b16x2	b.l15x2	6.63202	No	Yes	0	5	9
545	b.b16x4	b.b16x6	7.76556	Yes	Yes	5	6	8
546	b.b16x4	b.b17x3	7.24646	Yes	No	5	6	5
547	b.b16x4	b.b17x6	11.774	Yes	No	0	6	7
548	b.b16x5	b.b17x4	2.77929	Yes	Yes	0	5	5
549	b.b16x5	b.b17x5	3.79885	Yes	No	0	5	7
550	b.b16x5	b.l20x1	5.89758	Yes	No	0	5	6
551	b.b16x6	b.b17x3	6.94803	Yes	No	5	8	5
552	b.b16x7	b.l16x3	9.17039	No	No	15	9	3
553	b.b16x7	b.b17x4	10.8144	No	Yes	15	9	5
554	b.b17x2	b.l16x3	4.89572	No	No	15	3	3
555	b.b17x4	b.l16x3	3.79869	Yes	No	15	5	3
556	b.b17x3	g.h1x10	4.60015	No	No	0	5	9
557	b.b17x5	b.b17x7	6.91029	No	Yes	4	7	8
558	b.b17x5	b.b21x1	12.263	No	Yes	4	7	7
559	b.b17x6	g.h1x14	5.69846	No	No	0	7	9
560	b.b17x7	b.b19x2	9.68781	Yes	Yes	4	8	6
561	b.b17x7	b.b20x6	9.33529	Yes	Yes	4	8	6
562	b.b17x7	b.b21x1	5.13967	Yes	Yes	4	8	7
563	b.l17x3	b.l17x7	7.65082	Yes	No	4	9	7
564	b.b19x4	b.l17x3	9.07816	Yes	Yes	4	8	9
565	b.b19x6	b.l17x3	12.045	No	Yes	4	9	9
566	b.b20x4	b.l17x3	17.8992	Yes	Yes	4	8	9
567	b.b20x6	b.l17x3	3.17266	Yes	Yes	4	6	9
568	b.l17x4	b.l19x2	6.8063	No	Yes	0	3	9
569	b.b20x4	b.l17x4	2.76947	Yes	No	0	8	3
570	b.l17x5	b.l17x6	3.0118	No	Yes	0	6	9
571	b.l17x6	b.l19x1	5.55113	Yes	No	0	9	9
572	b.b19x4	b.l17x7	4.64676	Yes	No	4	8	7
573	b.b18x1	b.l19x1	8.45304	No	No	0	9	9
574	b.b18x3	b.b19x2	4.7859	Yes	Yes	4	8	6
575	b.b18x3	b.b19x4	4.59712	Yes	Yes	4	8	8
576	b.b18x4	b.b22x5	2.80439	No	Yes	0	3	7
577	b.l18x1	b.l18x2	9.79269	Yes	Yes	12	6	7
578	b.l18x1	b.l18x3	6.63882	Yes	Yes	12	6	5
579	b.b22x5	b.l18x1	8.71596	Yes	Yes	12	7	6
580	b.l18x1	b.l22x4	4.35702	Yes	No	12	6	9
581	b.l18x1	g.h2x8	6.55026	Yes	No	0	6	7
582	b.l18x1	g.h2x11	3.74389	Yes	Yes	12	6	6
583	b.b22x5	b.l18x2	3.67904	Yes	Yes	12	7	7
584	b.l18x2	b.l22x4	3.91252	Yes	No	12	7	9
585	b.l18x2	g.h2x11	5.09366	Yes	Yes	12	7	6
586	b.l18x3	b.l18x5	7.89162	Yes	No	0	5	2
587	b.l18x3	g.h2x11	12.6366	Yes	Yes	12	5	6
588	b.l18x5	b.l20x2	8.82054	No	Yes	0	2	9
589	b.b19x2	b.b20x6	10.3036	Yes	Yes	4	6	6
590	b.b19x2	b.l20x1	2.77774	Yes	No	0	6	6
591	b.b19x3	b.b22x5	2.93633	No	Yes	0	4	7
592	b.b19x4	b.b20x6	7.27469	Yes	Yes	4	8	6
593	b.b19x5	b.l21x9	4.63093	No	No	0	5	6
594	b.b19x6	b.l19x2	6.71573	No	Yes	4	9	9
595	b.b20x2	b.l19x2	6.94356	No	Yes	0	6	9
596	b.b20x2	b.b20x4	6.32438	No	Yes	0	6	8
597	b.b20x2	b.l21x1	4.19302	No	No	0	6	2
598	b.b20x3	b.b21x7	4.40255	No	Yes	0	8	5
599	b.b20x3	b.l21x9	4.19659	No	No	0	8	6
600	b.b20x4	b.b20x6	4.76566	Yes	Yes	4	8	6
601	b.b20x4	b.b21x3	12.507	Yes	No	4	8	6
602	b.b20x4	b.b21x6	6.70247	Yes	No	4	8	1
603	b.b20x5	b.b21x4	3.30416	No	Yes	0	7	5
604	b.b20x6	b.b21x3	5.68887	Yes	No	4	6	6
605	b.b20x7	b.l20x3	3.97918	Yes	No	0	9	7
606	b.b20x7	b.b21x4	7.24712	Yes	Yes	0	9	5
607	b.b20x7	g.h2x4	3.7102	Yes	No	0	9	7
608	b.l20x2	g.l1x5	6.8128	Yes	No	0	9	4
609	b.l20x2	g.h2x7	5.48957	Yes	No	0	9	5
610	b.b21x1	g.l1x4	9.30249	Yes	No	0	7	8
611	b.b21x2	g.h2x1	3.5474	Yes	No	0	6	8
612	b.b21x3	b.b21x6	3.29344	No	No	4	6	1
613	b.b21x5	b.b21x7	8.6532	Yes	Yes	0	4	5
614	b.b21x7	b.b23x2	4.67816	Yes	No	0	5	6
615	b.b21x7	b.b24x6	7.39957	Yes	Yes	0	5	8
616	b.l21x2	b.l21x4	8.50397	Yes	No	0	4	4
617	b.b25x3	b.l21x2	6.65145	Yes	Yes	0	5	4
618	b.b23x6	b.l21x5	5.74172	Yes	No	0	7	4
619	b.b23x6	b.l21x7	3.2819	Yes	Yes	1	7	5
620	b.l21x7	b.l23x1	4.96042	Yes	Yes	1	5	6
621	b.l21x7	b.l23x2	6.6263	Yes	No	1	5	8
622	b.l21x8	b.l23x1	3.43478	No	Yes	0	4	6
623	b.b23x6	b.l21x9	9.56747	Yes	No	0	7	6
624	b.b22x1	b.l23x1	3.1881	No	Yes	1	8	6
625	b.b22x1	b.l25x6	3.93205	No	Yes	1	8	8
626	b.b22x2	b.b26x3	4.82798	No	Yes	0	8	6
627	b.b22x4	b.b26x3	3.26379	No	Yes	0	5	6
628	b.b22x4	b.b26x5	4.07795	No	No	0	5	7
629	b.b22x5	b.b23x2	10.2269	Yes	No	0	7	6
630	b.b23x1	b.l22x1	3.8212	No	No	0	5	9
631	b.l22x1	g.ctx3	7.22707	No	Yes	0	9	9
632	b.l22x3	g.ctx3	8.40075	No	Yes	0	9	9
633	b.b24x7	b.l22x5	11.5295	No	Yes	20	9	9
634	b.l22x5	g.ctx6	4.26826	Yes	Yes	0	9	6
635	b.b23x1	b.b24x5	4.89253	No	No	0	5	5
636	b.b23x3	b.b24x5	5.21409	No	No	0	7	5
637	b.b23x3	b.b26x3	3.37805	No	Yes	0	7	6
638	b.b23x3	b.b27x1	4.27261	No	No	0	7	6
639	b.b23x4	b.b23x6	4.36447	No	Yes	0	6	7
640	b.b23x6	b.l23x2	3.91513	Yes	No	1	7	8
641	b.b23x6	b.b24x4	10.3016	Yes	Yes	1	7	6
642	b.b23x6	b.b24x6	7.48712	Yes	Yes	1	7	8
643	b.l23x1	b.l25x6	18.2321	Yes	Yes	1	6	8
644	b.b24x2	b.l23x2	7.95646	No	No	0	5	8
645	b.b24x2	b.b25x6	3.752	No	No	0	5	3
646	b.b24x3	b.b25x7	4.45839	No	No	0	5	7
647	b.b24x4	b.b24x6	3.84014	Yes	Yes	1	6	8
648	b.b24x4	b.b25x3	9.90695	Yes	Yes	1	6	5
649	b.b24x4	b.b25x6	4.00351	Yes	No	1	6	3
650	b.b24x6	b.b25x3	4.05098	Yes	Yes	1	8	5
651	b.b24x7	b.l24x3	6.83711	No	Yes	0	9	5
652	b.l24x2	g.h2x12	3.76463	Yes	No	0	6	7
653	b.b25x2	b.l24x3	5.64678	No	Yes	0	2	5
654	b.b25x3	b.b25x6	2.95442	Yes	No	1	5	3
655	b.b25x7	b.b28x6	17.8702	No	Yes	10	7	9
656	b.l25x3	b.l25x7	2.99906	Yes	No	0	9	7
657	b.b27x3	b.l25x3	7.24554	No	Yes	0	8	9
658	b.b27x5	b.l25x3	13.602	No	Yes	10	9	9
659	b.l25x3	b.l28x2	6.06932	Yes	Yes	10	9	9
660	b.b28x4	b.l25x3	9.70024	Yes	Yes	10	6	9
661	b.l25x4	b.l28x2	5.61934	No	Yes	0	5	9
662	b.l25x5	b.l28x1	7.78341	No	Yes	0	7	9
663	b.l25x6	b.l28x1	20.4538	Yes	Yes	1	8	9
664	b.b26x1	b.b26x2	3.23786	No	No	0	9	7
665	b.b26x1	b.l28x1	5.33222	No	Yes	0	9	9
666	b.b26x3	b.b27x3	3.96364	Yes	No	0	6	8
667	b.b26x5	b.b27x1	4.41821	No	No	0	7	6
668	b.l27x1	b.l27x3	5.52015	No	No	3	8	7
669	b.l27x3	b.l27x5	6.29406	No	No	0	7	5
670	b.l27x5	g.ctx4	4.36725	No	No	0	5	7
671	b.l27x5	g.ctx15	5.23248	No	Yes	0	5	9
672	b.l27x6	g.ctx16	4.86726	No	Yes	0	7	8
673	b.b27x3	b.b28x6	7.71064	No	Yes	0	8	9
674	b.b27x5	b.l28x2	7.9234	No	Yes	10	9	9
675	b.b28x2	b.l28x2	9.34437	No	Yes	0	4	9
676	b.b28x4	b.b28x6	7.16679	Yes	Yes	10	6	9
677	b.b28x5	g.ctx16	3.91597	No	Yes	3	5	8
678	b.b28x7	g.ctx14	8.58435	No	Yes	3	9	9
679	b.b28x7	g.ctx16	3.1681	No	Yes	3	9	8
680	g.l1x2	g.l1x4	4.34857	No	No	0	2	8
681	g.h2x11	g.h2x15	15.268	Yes	No	0	6	6
682	g.ctx3	g.ctx4	4.03974	Yes	No	0	9	7
683	g.ctx3	g.ctx5	3.55534	Yes	No	0	9	9
684	g.ctx3	g.ctx6	7.32658	Yes	Yes	0	9	6
685	g.ctx10	g.ctx9	3.87345	No	No	3	5	6
686	g.ctx13	g.ctx9	3.97344	No	No	3	5	6
687	g.ctx10	g.ctx13	5.88533	No	No	3	5	5
688	g.ctx14	g.ctx15	5.08405	Yes	Yes	3	9	9
689	g.ctx14	g.ctx16	3.93058	Yes	Yes	3	9	8
690	g.ctx15	g.ctx16	3.59582	Yes	Yes	3	9	8
691	Lig	NT	3.24628	Yes	No	2	0	7
692	2x45	3x42	4.05732	No	No	0	9	8
693	2x53	7x42	4.65951	No	Yes	0	7	7
694	2x53	7x46	3.37809	No	No	0	7	9
695	2x60	Lig	7.07586	No	Yes	2	6	0
696	2x63	Lig	6.83508	No	Yes	2	4	0
697	3x29	Lig	4.18242	No	Yes	2	4	0
698	E2	Lig	22.544	Yes	Yes	2	3	0
699	6x58	Lig	7.63529	No	Yes	0	3	0
700	Lig	Lig	60.0385	Yes	Yes	2	0	0
701	G.S1.05	G.S4.02	3.72902	No	Yes	0	9	8
702	G.S2.01	b.l5x5	6.0487	No	Yes	1	9	9
703	G.S2.05	G.S3.02	5.04695	No	No	0	3	4
704	G.H2.02	b.l13x6	3.11781	Yes	Yes	1	8	9
705	G.H2.03	b.l13x6	4.98563	Yes	Yes	1	9	9
706	G.H2.06	b.b18x1	3.52824	Yes	No	0	9	9
707	G.H3.06	G.H4.15	3.4302	Yes	Yes	0	6	8
708	G.hgh4.03	G.hgh4.04	4.15009	No	No	0	5	6
709	G.H4.05	G.hgh4.08	5.63992	No	No	19	4	3
710	G.H4.03	G.H4.04	4.89635	Yes	No	0	4	4
711	G.H5.02	G.s6h5.04	4.13687	No	No	0	4	8
712	b.l22x5	b.lhb1x3	4.95452	Yes	Yes	0	9	2
713	b.b23x1	b.lhb1x9	3.07118	No	No	0	5	3
714	b.b1x5	b.b28x4	4.84078	No	Yes	0	3	6
715	b.b2x5	b.b3x2	11.3663	Yes	No	3	7	5
716	b.b2x5	b.l4x1	5.58699	Yes	No	0	7	5
717	b.b3x4	b.b4x6	5.53328	No	Yes	3	9	9
718	b.b10x3	b.b8x1	3.12611	No	No	0	8	8
719	b.b12x2	b.l13x1	3.58761	No	No	0	7	2
720	b.l13x3	b.l15x2	3.80615	Yes	Yes	5	9	9
721	b.l17x3	b.l19x2	2.87635	Yes	Yes	4	9	9
722	b.l17x5	b.l19x2	4.34727	No	Yes	0	6	9
723	b.b20x5	b.b21x7	5.33451	No	Yes	0	7	5
724	b.l22x2	g.ctx2	2.83887	No	No	0	1	3
725	b.l22x5	b.l24x2	7.33034	Yes	Yes	0	9	6
726	g.ctx2	g.h2x15	3.62146	No	No	0	3	6
727	g.ctx12	g.ctx13	2.98927	No	No	0	6	5
728	b.1x12	b.1x15	3.69932	Yes	No	0	6	7
729	b.1x18	b.b21x1	3.04684	No	Yes	0	4	7
730	b.lh12x2	g.h2x2	4.73698	No	No	0	8	9
731	b.h2x5	b.lhb1x3	2.73516	Yes	Yes	0	5	2
732	b.lhb1x10	b.lhb1x8	3.74335	No	No	0	0	2
733	b.lhb1x11	b.lhb1x9	2.92023	Yes	No	0	0	3
734	b.b1x1	b.lhb1x10	2.7817	No	No	0	5	0
735	b.b25x7	b.lhb1x11	4.78314	No	Yes	10	7	0
736	b.b28x6	b.lhb1x11	3.28117	Yes	Yes	10	9	0
737	b.lhb1x11	g.ctx5	3.22074	Yes	No	0	0	9
738	b.l1x3	b.l3x2	3.04697	Yes	Yes	3	9	9
739	G.H2.10	b.l3x1	3.43432	No	No	1	7	9
740	b.b14x3	b.b15x1	3.74755	Yes	Yes	5	5	9
741	b.b16x7	b.l14x6	3.73525	No	No	0	9	3
742	G.H2.03	b.l15x1	3.6441	Yes	Yes	1	9	7
743	b.l21x2	b.l21x5	3.29204	Yes	No	0	4	4
744	g.h1x10	g.h1x14	4.9938	No	No	0	9	9
745	g.h2x3	g.l1x5	3.01021	No	No	0	5	4
746	g.ctx14	g.ctx9	2.96527	Yes	No	3	9	6
747	3x44	5x53	3.2265	No	No	0	7	6
748	G.H1.04	G.S5.07	3.9778	No	Yes	7	7	9
749	G.H2.03	G.H2.06	4.43365	Yes	Yes	1	9	9
750	G.H2.05	G.H2.06	2.87508	No	Yes	1	8	9
751	G.HG.13	G.s4h3.04	3.88611	Yes	Yes	13	7	8
752	G.s4h3.05	G.s4h3.06	2.867	Yes	No	0	9	8
753	G.H3.02	G.hgh4.02	3.06677	No	Yes	0	8	7
754	G.H3.06	G.hgh4.02	5.15079	Yes	Yes	0	6	7
755	G.H3.09	G.S5.04	3.62361	Yes	Yes	8	9	9
756	G.H3.09	G.H4.15	3.67393	Yes	Yes	8	9	8
757	G.H3.10	G.h4s6.01	4.68263	No	No	0	5	4
758	G.H4.14	G.hgh4.02	8.38117	No	Yes	18	5	7
759	G.H4.16	G.S6.01	4.12726	No	No	0	3	5
760	5x68	G.H5.13	3.30835	No	Yes	0	6	8
761	b.b17x2	b.b17x4	2.87182	No	Yes	15	3	5
762	3x33	3x37	4.53928	Yes	Yes	0	4	6
763	I2x52	I2x56	3.48695	No	No	0	4	3
764	E2x51	Lig	4.72227	No	Yes	2	4	0
765	5x43	6x52	2.82915	No	Yes	2	5	7
766	E2x52	Lig	3.76737	No	Yes	2	4	0
767	5x36	6x59	2.98098	No	No	0	4	4
768	1x39	7x39	5.28943	Yes	No	0	7	6
769	4x64	E2	10.1462	No	Yes	2	5	3
770	7x31	Lig	4.73734	No	Yes	2	4	0
771	b.1x13	b.1x16	2.92415	No	Yes	0	1	4
772	2x64	Lig	3.45459	No	Yes	2	5	0
773	4x38	G.HN.52	2.94758	No	No	0	7	4
774	b.l5x4	b.l5x5	6.05339	No	Yes	0	8	9
775	2x43	7x53	3.3634	No	Yes	6	8	9
776	4x60	5x39	3.44917	No	No	0	5	6
777	5x32	5x35	3.68937	No	No	2	3	1
778	g.h1x12	g.h1x9	2.9303	No	No	0	6	6
779	4x63	4x64	4.65114	No	No	0	5	5
780	E3	Lig	12.8782	Yes	Yes	2	2	0
781	1x39	7x42	4.03083	Yes	Yes	2	7	7
782	7x27	Lig	3.44889	No	Yes	0	3	0
783	G.H5.17	G.h4s6.12	4.3125	No	Yes	0	5	4
784	G.H5.13	G.H5.17	5.95809	Yes	No	0	8	5
785	2x551	3x31	3.5275	No	No	0	0	5
786	E1	Lig	4.27952	No	Yes	0	0	0
787	3x28	3x29	3.18904	No	No	0	5	4
788	3x29	4x65	7.26694	No	No	0	4	0
789	3x30	4x62	7.06012	No	No	0	6	4
790	3x33	4x61	4.93035	Yes	No	0	4	5
791	4x59	4x60	3.13503	No	No	0	8	5
792	4x61	5x39	3.31051	No	No	0	5	6
793	4x65	E2x52	5.11551	No	No	0	0	4
794	5x58	6x41	2.73189	Yes	No	0	9	8
795	3x47	5x57	2.72872	No	No	0	9	8
796	3x33	4x57	2.72769	Yes	No	0	4	6
797	5x68	G.H5.16	2.701	No	No	0	6	6
798	G.H1.07	G.s6h5.05	2.69504	No	No	0	9	9
799	2x54	7x46	2.68743	No	No	0	5	9
800	G.H1.01	G.s1h1.01	2.68579	Yes	No	0	9	9
801	2x37	G.H5.22	2.68513	No	No	0	7	4
802	b.b18x2	b.b22x3	2.68432	No	No	0	5	6
803	1x36	2x65	2.6822	No	No	0	5	4
804	b.b15x1	b.l16x1	2.68118	Yes	No	0	9	4
805	b.b24x1	b.l25x5	2.67995	No	No	0	4	7
806	b.1x15	b.1x19	2.67816	No	No	0	7	6
807	2x66	E1x49	2.65135	No	No	0	4	5
808	b.h2x5	g.h2x9	2.64962	Yes	No	0	5	4
809	b.b28x1	b.b28x2	2.64527	No	No	0	4	4
810	G.H4.01	G.HG.14	2.64035	No	No	0	3	5
811	g.h1x5	g.h1x9	2.63632	No	No	0	6	6
812	G.S5.07	G.s5hg.01	2.62895	Yes	No	0	9	9
813	2x42	4x45	2.62435	Yes	No	0	7	5
814	G.hgh4.02	G.hgh4.04	2.618	Yes	No	0	7	6
815	b.b24x2	b.l25x1	2.61726	No	No	0	5	3
816	b.lhb1x1	b.lhb1x2	2.61396	No	No	0	3	1
817	b.l14x1	b.l14x3	2.57514	No	No	0	4	5
818	b.l27x2	b.l2x2	2.57184	No	No	0	5	1
819	8x47	G.H5.24	2.56289	No	No	0	8	8
820	b.l27x4	g.ctx4	2.56167	No	No	0	9	7
821	G.HN.45	G.HN.49	2.55443	No	No	0	4	4
822	b.b21x5	b.b25x1	2.55212	Yes	No	0	4	2
823	G.h4s6.12	I3	2.54166	Yes	No	0	4	3
824	b.lhb1x4	b.lhb1x5	2.54081	No	No	0	1	1
825	b.b10x5	b.l6x2	2.53977	Yes	No	0	9	6
826	4x41	4x45	2.50633	No	No	0	4	5
827	b.b11x2	b.b12x6	2.50535	No	Yes	0	7	8
828	b.b5x3	b.l1x2	2.49505	Yes	No	0	9	9
829	b.b19x1	b.l18x1	2.49107	No	Yes	0	6	6
830	b.b26x4	b.b2x5	2.48868	No	Yes	0	5	7
831	g.ctx1	g.ctx2	2.48654	No	No	0	1	3
832	2x41	4x39	2.486	No	No	0	5	1
833	G.HN.37	G.HN.41	2.47512	No	No	0	3	4
834	2x51	2x55	2.47113	No	No	0	7	5
835	G.HN.53	G.hns1.03	2.4706	No	No	0	1	4
836	5x37	6x60	2.45428	No	No	0	2	5
837	b.l14x2	b.l18x4	2.44269	No	No	0	4	7
838	6x56	6x60	2.44044	No	No	0	5	5
839	b.b23x5	b.l25x7	2.43031	No	No	0	7	7
840	7x26	E3	2.42474	No	Yes	2	0	2
841	5x63	5x67	2.42141	No	No	0	2	3
842	G.H1.01	G.s3h2.01	2.41744	Yes	No	0	9	9
843	b.l1x4	b.l3x2	2.41563	No	Yes	0	6	9
844	5x64	5x68	2.39996	No	No	0	5	6
845	b.b16x3	b.b19x2	2.39747	No	Yes	0	6	6
846	b.1x1	b.1x5	2.39614	No	No	0	0	3
847	2x49	3x39	2.39478	No	No	0	8	9
848	G.HG.17	G.s4h3.05	2.39297	No	Yes	0	3	9
849	G.H3.03	G.H3.06	2.38866	No	Yes	0	4	6
850	1x56	8x54	2.36727	No	Yes	0	7	6
851	b.h2x2	b.lh12x4	2.36581	No	No	0	1	3
852	G.s4h3.07	G.s4h3.15	2.36073	No	No	0	5	9
853	1x60	8x57	2.35942	Yes	No	0	4	7
854	G.H5.15	I2x54	2.35902	No	No	0	7	4
855	b.b24x5	b.b25x5	2.35504	No	No	0	5	4
856	b.b10x5	b.b6x4	2.34672	Yes	No	0	9	7
857	6x57	E3	2.34573	No	Yes	0	5	2
858	3x53	I2x57	2.33948	No	No	0	8	7
859	b.b2x2	b.b6x3	2.33748	No	No	0	7	8
860	6x49	6x53	2.31198	Yes	No	0	5	6
861	1x57	2x40	2.30585	No	Yes	0	7	8
862	b.b27x4	b.b28x3	2.29357	No	Yes	0	5	7
863	b.1x12	b.1x16	2.29017	Yes	Yes	0	6	4
864	b.l13x5	b.l15x2	2.28562	No	Yes	0	5	9
865	G.H5.07	G.S5.05	2.2849	No	Yes	0	8	9
866	b.b25x4	b.lhb1x9	2.26343	No	No	0	4	3
867	8x48	8x52	2.26303	No	No	0	5	5
868	g.ctx7	g.ctx8	2.26073	No	No	0	4	8
869	G.HN.44	G.HN.48	2.25812	No	No	0	6	3
870	5x65	G.H5.20	2.2566	No	Yes	0	8	9
871	G.H5.15	G.H5.19	2.24717	No	Yes	0	7	8
872	3x37	3x41	2.24083	Yes	No	0	6	5
873	1x46	2x54	2.23987	No	No	0	8	5
874	2x39	3x49	2.21778	No	No	0	8	8
875	2x43	7x54	2.21684	No	Yes	0	8	6
876	b.b12x6	b.l9x2	2.21111	Yes	No	0	8	5
877	6x28	6x31	2.20299	No	No	0	4	5
878	b.b7x5	b.l9x7	2.1944	No	No	0	9	7
879	1x42	7x43	2.19034	No	No	0	7	5
880	b.1x19	b.b21x2	2.18322	No	Yes	0	6	6
881	G.s6h5.02	G.s6h5.04	2.18163	No	No	0	7	8
882	1x48	1x49	2.14334	No	No	0	5	8
883	1x32	2x65	2.13038	Yes	No	0	4	4
884	1x54	2x44	2.12889	No	No	0	7	6
885	b.b22x3	b.b23x2	2.12402	No	No	0	6	6
886	b.1x7	g.h1x8	2.12305	No	Yes	0	8	7
887	b.b16x2	b.l17x1	2.12259	No	No	0	5	2
888	3x27	3x31	2.12152	No	No	0	5	5
889	b.h2x1	g.h2x5	2.11797	Yes	No	0	5	6
890	b.b6x1	b.l7x1	2.11694	No	No	0	9	9
891	G.HN.43	b.b5x6	2.1115	No	No	0	9	6
892	6x43	7x52	2.11096	No	No	0	7	8
893	G.h2s4.01	G.h2s4.04	2.10696	Yes	No	0	9	9
894	8x48	G.H5.26	2.10583	No	Yes	0	5	5
895	b.1x2	b.1x5	2.10304	No	No	0	0	3
896	5x59	5x63	2.07344	No	No	0	3	2
897	G.H4.06	G.HG.04	2.06996	No	Yes	0	7	9
898	3x30	4x57	2.06643	No	No	0	6	6
899	I1x48	I1x51	2.05468	No	No	0	6	7
900	b.b21x5	b.h2x2	2.05205	Yes	No	0	4	1
901	g.h1x1	g.h1x5	2.04233	Yes	No	0	0	6
902	3x41	4x52	2.03266	No	No	0	5	4
903	G.h4s6.04	G.h4s6.11	2.02426	No	Yes	0	4	7
904	g.h1x12	g.h1x8	2.01965	No	Yes	0	6	7
905	5x62	6x37	2.01744	No	No	0	5	8
906	b.b18x5	b.l18x4	2.0105	Yes	No	0	5	7
907	2x62	2x66	2.00571	No	No	0	3	4
908	3x37	5x461	2.00103	Yes	No	0	6	5
909	1x46	7x47	1.98671	No	No	0	8	8
910	G.HN.45	G.HN.48	1.98139	No	No	0	4	3
911	G.HG.02	G.s6h5.02	1.96436	No	No	0	9	7
912	G.H5.01	G.s6h5.05	1.96276	No	No	0	9	9
913	G.HN.52	G.hns1.03	1.92612	No	No	0	4	4
914	1x31	7x32	1.9186	No	No	0	4	1
915	6x43	7x48	1.90752	No	No	0	7	6
916	g.h2x14	g.h2x15	1.90462	No	No	0	4	6
917	2x37	2x39	1.90035	No	No	0	7	8
918	5x31	E2	1.88038	No	Yes	0	4	3
919	b.1x6	g.h1x8	1.87714	No	Yes	0	3	7
920	b.b28x6	b.l25x2	1.86744	Yes	No	0	9	5
921	1x32	2x64	1.86285	Yes	No	0	4	5
922	2x48	2x52	1.84976	No	No	0	7	7
923	1x30	1x31	1.84654	No	No	0	3	4
924	G.HN.42	G.HN.45	1.84449	No	No	0	4	4
925	b.l8x4	b.l8x5	1.83204	No	No	0	3	3
926	G.HN.51	b.l1x4	1.82014	No	No	0	5	6
927	1x52	8x54	1.81558	No	Yes	0	6	6
928	1x45	7x47	1.80713	No	No	0	5	8
929	5x66	5x69	1.80692	No	No	0	4	0
930	b.b9x2	b.b9x4	1.79125	No	No	0	5	9
931	b.b17x2	g.h1x13	1.78607	No	No	0	3	1
932	5x45	5x48	1.77721	No	No	0	5	4
933	b.h2x3	b.lh12x3	1.76242	No	No	0	1	4
934	6x32	G.H5.26	1.76033	No	Yes	0	7	5
935	G.HG.05	G.HG.06	1.75509	No	No	0	5	5
936	2x40	I1x52	1.75462	Yes	No	0	8	0
937	b.l2x2	b.l6x2	1.75	No	No	0	1	6
938	b.b13x1	b.l12x3	1.74	No	No	0	4	5
939	G.HG.12	G.HG.13	1.73149	No	Yes	0	1	7
940	5x66	6x30	1.72895	No	No	0	4	6
941	5x34	5x35	1.72373	Yes	No	0	1	1
942	I1x49	b.l25x4	1.70979	No	No	0	6	5
943	G.H1.03	G.s1h1.06	1.70722	No	No	0	9	9
944	8x54	8x58	1.6875	Yes	No	0	6	0
945	b.h2x4	g.h2x9	1.68648	No	No	0	3	4
946	3x52	3x56	1.6723	No	No	0	5	6
947	b.l7x5	b.l9x1	1.67183	No	No	0	6	5
948	b.b12x1	b.l13x5	1.66833	No	No	0	6	5
949	1x29	1x32	1.66614	No	Yes	0	2	4
950	b.1x14	b.1x18	1.66497	No	No	0	4	4
951	4x40	4x44	1.6462	No	No	0	3	3
952	G.H1.05	G.S2.04	1.64512	No	No	0	6	6
953	b.1x2	b.1x3	1.63979	No	No	0	0	1
954	2x41	4x46	1.6196	No	Yes	0	5	7
955	b.lhb1x6	b.lhb1x7	1.60803	No	No	0	3	1
956	G.H3.05	G.s1h1.02	1.60195	No	No	0	9	7
957	G.H5.19	I2x53	1.5947	Yes	No	0	8	6
958	b.1x1	b.1x4	1.58491	No	No	0	0	8
959	G.hfs2.06	b.l7x4	1.58437	No	Yes	0	0	9
960	G.HN.11	G.HN.34	1.58068	Yes	No	0	2	3
961	1x51	2x51	1.57959	No	No	0	4	7
962	4x38	4x40	1.57755	No	No	0	7	3
963	g.ctx6	g.ctx7	1.56114	Yes	No	0	6	4
964	b.1x11	g.h1x12	1.55806	No	No	0	8	6
965	b.1x4	g.h1x8	1.55413	No	Yes	0	8	7
966	3x31	3x35	1.54977	No	No	0	5	8
967	b.b20x1	b.l21x5	1.54306	No	No	0	5	4
968	2x63	2x67	1.52303	No	No	0	4	2
969	G.HN.38	G.HN.41	1.52019	No	No	0	3	4
970	6x39	7x52	1.51863	No	No	0	6	8
971	b.b16x4	b.l13x2	1.51736	Yes	No	0	6	6
972	5x40	5x41	1.50635	No	No	0	4	4
973	b.1x13	b.1x9	1.50591	No	No	0	1	4
974	1x30	Lig	1.49231	No	Yes	2	3	0
975	1x56	8x53	1.48962	No	No	0	7	6
976	7x55	7x56	1.48118	No	No	0	6	7
977	6x25	6x26	1.48	No	No	0	3	3
978	3x21	E1x50	1.47894	No	Yes	0	7	8
979	b.b21x7	b.l24x1	1.46205	Yes	No	0	5	5
980	6x23	G.h4s6.12	1.45827	No	Yes	0	2	4
981	1x60	8x53	1.4398	Yes	No	0	4	6
982	b.lh12x2	b.lh12x3	1.41809	No	No	0	8	4
983	b.l17x1	b.l17x2	1.39944	No	No	0	2	6
984	6x28	6x32	1.39652	No	No	0	4	7
985	G.H1.08	G.H1.10	1.39618	No	No	0	8	8
986	b.1x4	g.h1x4	1.37198	No	No	0	8	5
987	6x27	6x30	1.36833	No	No	0	1	6
988	g.h1x11	g.h1x7	1.36692	No	No	0	9	2
989	5x51	5x55	1.34941	No	No	0	6	5
990	b.1x22	g.l1x4	1.34233	No	No	0	3	8
991	b.1x12	g.h1x11	1.33382	Yes	No	0	6	9
992	G.HN.32	G.HN.33	1.33058	No	Yes	0	5	4
993	b.b16x1	b.l17x3	1.31936	No	Yes	0	4	9
994	1x32	1x33	1.30346	Yes	No	0	4	5
995	7x55	8x50	1.30171	No	Yes	0	6	8
996	G.s4h3.11	G.s4h3.13	1.29699	No	No	0	8	4
997	5x64	5x67	1.29256	No	No	0	5	3
998	b.1x10	b.1x11	1.29073	No	No	0	1	8
999	G.s4h3.08	G.s4h3.10	1.28988	No	Yes	0	8	9
1000	G.S4.05	G.s1h1.05	1.28947	No	No	0	7	9
1001	6x32	6x35	1.2843	No	No	0	7	5
1002	G.h2s4.02	G.h2s4.03	1.2763	No	No	0	7	5
1003	b.1x14	g.h1x15	1.27028	No	No	0	4	8
1004	7x29	7x33	1.26083	No	No	0	2	4
1005	G.HN.36	b.b5x2	1.21378	No	Yes	0	4	7
1006	2x40	I1x51	1.19562	Yes	No	0	8	7
1007	b.1x16	b.1x17	1.19111	Yes	No	0	4	2
1008	b.1x12	b.1x8	1.16806	Yes	No	0	6	5
1009	1x49	7x50	1.15071	No	No	0	8	9
1010	6x42	6x46	1.14101	No	No	0	4	6
1011	G.H3.04	G.H3.07	1.13637	No	No	0	9	5
1012	5x33	5x34	1.13603	No	Yes	0	1	1
1013	G.HG.09	G.HG.12	1.12114	No	No	0	2	1
1014	2x40	I1x50	1.10607	Yes	No	0	8	7
1015	1x41	1x45	1.07732	No	No	0	4	5
1016	G.HN.51	G.hns1.01	1.07679	No	No	0	5	3
1017	7x28	Lig	1.04788	No	Yes	0	1	0
1018	G.H4.13	G.H4.17	1.04324	No	No	0	3	4
1019	b.b1x3	g.ctx18	1.03673	Yes	No	0	7	6
1020	G.H3.03	G.s4h3.14	1.02128	No	No	0	4	6
1021	b.lhb1x2	b.lhb1x3	1.01891	No	Yes	0	1	2
1022	5x66	5x70	1.00308	No	No	0	4	0
1023	g.ctx6	g.h2x16	0.991032	Yes	No	0	6	4
1024	7x36	7x40	0.980598	No	No	0	4	8
1025	G.s3h2.01	G.s3h2.02	0.964218	No	No	0	9	9
1026	G.HN.46	G.HN.49	0.95721	No	No	0	4	4
1027	G.s1h1.02	G.s1h1.03	0.954762	No	No	0	7	8
1028	7x23	E3	0.941667	No	Yes	2	0	2
1029	b.l21x2	b.l21x3	0.94	Yes	No	0	4	3
1030	b.b1x4	g.ctx17	0.927479	Yes	No	0	7	7
1031	1x54	1x58	0.92297	No	No	0	7	3
1032	b.l8x3	b.l8x6	0.922222	No	No	0	3	4
1033	g.ntx1	g.ntx4	0.916923	No	No	0	0	0
1034	b.1x2	b.ntx2	0.914658	No	No	0	0	0
1035	1x28	1x31	0.896154	No	No	0	0	4
1036	G.H3.04	G.s4h3.14	0.876947	No	No	0	9	6
1037	b.lhb1x3	g.h2x13	0.853526	Yes	No	0	2	1
1038	5x48	5x52	0.841923	No	No	0	4	3
1039	G.H1.06	G.H1.07	0.82938	No	No	0	9	9
1040	G.H1.09	G.S2.06	0.80547	No	Yes	0	7	9
1041	7x25	7x26	0.801923	No	No	0	0	0
1042	b.1x16	b.1x20	0.790662	Yes	No	0	4	2
1043	1x44	1x48	0.784423	No	No	0	6	5
1044	G.s4h3.10	G.s4h3.13	0.780769	Yes	No	0	9	4
1045	1x34	1x38	0.77927	No	No	0	4	5
1046	G.H2.01	G.H2.07	0.769231	No	Yes	0	9	9
1047	5x24	5x27	0.753248	No	No	0	0	0
1048	G.s4h3.09	G.s4h3.10	0.748086	No	Yes	0	4	9
1049	6x34	6x38	0.717588	No	No	0	6	5
1050	G.H1.02	G.H1.06	0.716453	No	No	0	9	9
1051	G.H1.11	G.H1.12	0.713846	No	No	0	7	0
1052	G.HN.33	G.HN.37	0.696813	Yes	No	0	4	3
1053	1x25	Lig	0.685769	No	Yes	0	0	0
1054	2x40	I1	0.684719	Yes	No	0	8	0
1055	8x56	b.b24x1	0.657692	No	No	0	3	4
1056	b.1x3	b.ntx3	0.654365	No	No	0	1	0
1057	7x54	7x60	0.648352	Yes	No	0	6	0
1058	5x34	5x38	0.64312	Yes	No	0	1	3
1059	1x60	CT	0.641868	Yes	No	0	4	0
1060	4x46	4x47	0.636603	Yes	No	0	7	4
1061	6x62	7x23	0.633077	No	No	0	0	0
1062	g.h3x11	g.h3x15	0.633077	No	No	0	0	0
1063	6x38	6x42	0.628718	No	No	0	5	4
1064	7x24	E3	0.624835	No	Yes	2	0	2
1065	5x72	I3	0.608846	No	No	0	0	3
1066	2x36	G.H5.22	0.602308	No	No	0	0	4
1067	4x44	4x48	0.601068	No	No	0	3	2
1068	b.1x21	b.b21x2	0.594038	No	Yes	0	3	6
1069	1x33	1x37	0.590556	No	No	0	5	5
1070	g.h3x6	g.h3x9	0.581538	No	No	0	0	0
1071	g.h1x6	g.h1x9	0.569039	No	No	0	4	6
1072	5x28	E2	0.54547	No	Yes	2	0	3
1073	3x23	3x26	0.537332	No	No	0	1	6
1074	7x61	CT	0.531978	No	No	0	0	0
1075	G.HN.09	G.HN.10	0.527222	No	No	0	5	4
1076	G.HG.02	G.s6h5.03	0.520556	No	No	0	9	9
1077	G.s4h3.10	G.s4h3.12	0.520128	Yes	No	0	9	4
1078	6x24	I3	0.518269	No	No	0	3	3
1079	G.H4.17	G.h4s6.08	0.513755	No	No	0	4	3
1080	g.h1x3	g.h1x6	0.503974	No	No	0	3	4
1081	5x29	5x32	0.463462	No	No	0	0	3
1082	1x61	8x53	0.455812	No	No	0	0	6
1083	3x52	I2	0.444231	No	No	0	5	0
1084	5x71	5x72	0.430192	No	No	0	0	0
1085	g.h1x1	g.ntx4	0.426514	Yes	No	0	0	0
1086	8x54	8x55	0.421966	Yes	No	0	6	5
1087	b.b20x7	g.h3x4	0.418846	Yes	No	0	9	0
1088	G.hgh4.06	G.hgh4.07	0.411111	No	No	0	3	7
1089	b.l18x3	g.h3x11	0.402692	Yes	No	0	5	0
1090	1x36	1x40	0.398397	No	No	0	5	4
1091	b.l22x3	g.l3x4	0.396538	No	No	0	9	0
1092	b.1x3	b.ntx1	0.388846	No	No	0	1	0
1093	4x47	4x51	0.386282	No	No	0	4	4
1094	1x27	7x31	0.384231	No	No	0	0	4
1095	g.ctx11	g.ctx17	0.378712	No	No	0	4	7
1096	8x55	8x60	0.371154	No	No	0	5	0
1097	5x25	5x26	0.349316	No	No	0	0	0
1098	g.h1x3	g.ntx3	0.34739	No	No	0	3	0
1099	g.h2x6	g.h2x9	0.344509	No	No	0	2	4
1100	g.l1x1	g.l1x2	0.335833	No	No	0	1	2
1101	8x58	8x59	0.334487	No	No	0	0	0
1102	2x34	2x36	0.333077	No	No	0	0	0
1103	1x23	1x24	0.312308	No	No	0	0	0
1104	5x25	5x28	0.307949	No	No	0	0	0
1105	G.H1.11	G.S2.08	0.302991	No	Yes	0	7	5
1106	5x27	E2	0.298974	No	Yes	2	0	3
1107	g.h1x2	g.h1x5	0.283397	No	No	0	2	6
1108	g.h3x3	g.l3x4	0.280769	No	No	0	0	0
1109	6x60	6x64	0.278462	No	No	0	5	0
1110	4x55	4x56	0.273846	No	No	0	3	5
1111	2x35	G.H5.19	0.264231	No	Yes	0	0	8
1112	g.h3x10	g.h3x6	0.25	No	No	0	0	0
1113	b.h2x5	g.h3x9	0.248846	Yes	No	0	5	0
1114	g.h3x1	g.l3x4	0.247692	No	No	0	0	0
1115	G.H5.09	G.s2s3.02	0.233333	No	No	0	4	3
1116	b.l20x2	g.h3x7	0.223846	Yes	No	0	9	0
1117	g.h3x13	g.h3x9	0.223846	No	No	0	0	0
1118	4x54	4x58	0.212308	No	No	0	4	4
1119	g.ctx17	g.ctx19	0.210879	No	No	0	7	8
1120	G.HN.10	G.HN.34	0.201923	No	No	0	4	3
1121	G.H5.21	G.H5.27	0.197778	No	No	0	5	0
1122	G.hns1.02	I2x55	0.196538	No	No	0	4	5
1123	b.b21x4	g.h3x5	0.183077	Yes	No	0	5	0
1124	g.h3x14	g.h3x15	0.178846	No	No	0	0	0
1125	b.l24x2	g.h3x12	0.171923	Yes	No	0	6	0
1126	b.lhb1x11	g.h3x2	0.163077	Yes	No	0	0	0
1127	g.h1x1	g.ntx2	0.158681	Yes	No	0	0	0
1128	g.l1x2	g.l1x3	0.149573	No	No	0	2	1
1129	G.HN.30	G.HN.31	0.143022	No	No	0	7	1
1130	g.h2x10	g.h2x13	0.12906	No	No	0	3	1
1131	b.ntx1	b.ntx4	0.119829	No	No	0	0	0
1132	g.h1x1	g.ntx8	0.119231	Yes	No	0	0	0
1133	5x37	6x63	0.115897	No	No	0	2	0
1134	5x30	5x34	0.11547	No	Yes	0	0	1
1135	G.hfs2.05	b.l7x4	0.112308	No	Yes	0	0	9
1136	b.l18x1	g.h3x8	0.100769	Yes	No	0	6	0
1137	1x26	1x27	0.1	No	No	0	0	0
1138	G.hfs2.04	b.b9x3	0.0923077	No	Yes	0	0	6
1139	1x23	NT	0.0753846	No	No	0	0	7
1140	1x23	7x24	0.0753846	No	No	0	0	0
1141	G.H4.08	G.H4.12	0.0741026	No	Yes	0	3	5
1142	G.HN.35	G.HN.38	0.0677564	No	No	0	4	3
1143	7x57	CT	0.0659341	No	No	0	0	0
1144	b.l21x6	b.l21x7	0.0630769	No	Yes	0	3	5
1145	b.l20x3	g.l2x4	0.0619231	No	No	0	7	0
1146	1x22	E3	0.0607692	No	Yes	0	0	2
1147	5x73	G.H5.13	0.0592308	No	Yes	0	0	8
1148	5x72	5x75	0.0584615	No	No	0	0	0
1149	G.HN.08	G.HN.11	0.0563736	No	Yes	0	0	2
1150	g.h3x3	g.l2x5	0.0542308	No	No	0	0	0
1151	7x58	G.H5.21	0.0447253	No	No	0	0	5
1152	7x58	7x59	0.018022	No	No	0	0	0
1153	7x59	7x61	0.018022	No	No	0	0	0
1154	G.HN.02	G.HN.11	0.0146154	No	Yes	0	0	2
1155	b.b5x1	g.ctx21	0.0142857	No	No	0	5	0
1156	G.HN.29	G.HN.30	0.0138462	No	No	0	0	7
1157	G.hfs2.03	G.hfs2.05	0.0135897	No	No	0	0	0
1158	g.h1x1	g.ntx7	0.00692308	Yes	No	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	1x32	1.74071	4	0	4
2	1x39	3.82267	6	2	7
3	1x60	1.86048	4	0	4
4	2x40	2.13909	6	0	8
5	2x42	3.69844	6	0	7
6	2x46	4.16078	4	6	9
7	2x50	5.23364	5	6	9
8	2x57	5.67534	4	2	7
9	E1x50	5.86204	6	2	8
10	E1x52	5.82383	4	0	6
11	3x33	4.47584	4	2	4
12	3x37	3.9438	5	0	6
13	3x43	3.62277	4	6	8
14	3x46	3.97821	4	6	9
15	3x50	5.54985	5	6	9
16	4x46	3.19847	4	0	7
17	E2	13.4919	15	2	3
18	5x34	0.904586	4	0	1
19	5x44	3.78639	4	2	6
20	5x47	5.71126	4	2	8
21	5x58	5.29487	6	6	9
22	6x48	5.39593	6	0	8
23	6x49	3.82489	4	0	5
24	6x52	4.94096	5	2	7
25	E3	4.75183	10	2	2
26	7x38	3.75665	5	2	5
27	7x42	4.91337	6	2	7
28	7x49	4.21825	4	6	9
29	7x53	4.30719	5	6	9
30	7x54	2.92967	4	0	6
31	8x50	3.63126	4	0	8
32	8x54	1.57308	4	0	6
33	G.HN.11	1.24838	4	0	2
34	G.HN.33	2.65065	4	0	4
35	G.S1.02	5.23785	4	9	5
36	G.S1.06	4.39355	4	7	8
37	G.H1.01	4.1112	4	7	9
38	G.S2.06	6.38839	4	0	9
39	G.S2.08	6.41537	5	9	5
40	G.S3.01	4.20273	4	9	4
41	G.S3.03	7.07258	5	9	7
42	G.S3.04	7.3439	4	1	6
43	G.S3.06	7.632	5	1	5
44	G.H2.02	3.60675	4	1	8
45	G.H2.03	4.73257	4	1	9
46	G.H2.04	3.97029	4	0	9
47	G.H2.06	5.14024	7	1	9
48	G.H2.07	4.10668	8	1	9
49	G.h2s4.01	5.56437	6	1	9
50	G.S4.02	4.47888	4	17	8
51	G.S4.03	3.41982	4	7	7
52	G.S4.04	6.04727	4	8	9
53	G.s4h3.04	5.54752	6	13	8
54	G.s4h3.05	5.52069	5	13	9
55	G.s4h3.10	0.834717	4	0	9
56	G.H3.01	4.90331	4	0	9
57	G.H3.06	3.5168	4	0	6
58	G.H3.09	5.01716	7	8	9
59	G.H3.17	6.62219	6	1	5
60	G.H3.18	5.79893	4	17	9
61	G.S5.03	3.07188	4	7	8
62	G.S5.04	3.85697	5	8	9
63	G.S5.05	3.46947	7	7	9
64	G.S5.07	3.72721	5	7	9
65	G.HG.04	5.41604	5	0	9
66	G.HG.13	3.12887	4	13	7
67	G.hgh4.02	5.3303	7	18	7
68	G.hgh4.05	8.46534	4	0	7
69	G.H4.03	6.54455	4	0	4
70	G.H4.12	5.77881	4	8	5
71	G.H4.15	4.34438	4	8	8
72	G.h4s6.02	4.9344	4	8	8
73	G.h4s6.11	3.84579	4	8	7
74	G.h4s6.12	4.51506	5	0	4
75	G.S6.02	6.37906	4	0	7
76	G.H5.08	5.54834	5	9	8
77	G.H5.13	3.91714	4	0	8
78	G.H5.19	1.95404	4	0	8
79	G.H5.20	3.34716	4	0	9
80	G.H5.26	3.73227	5	0	5
81	b.1x12	2.12284	4	0	6
82	b.1x16	1.79902	4	0	4
83	b.h2x1	3.92834	4	0	5
84	b.h2x5	2.77294	5	0	5
85	b.lhb1x3	2.45886	5	0	2
86	b.b1x3	4.39407	4	3	7
87	b.b1x4	3.27498	4	3	7
88	b.b1x6	8.13814	4	3	9
89	b.l1x3	8.02406	6	3	9
90	b.b2x1	7.78116	5	1	8
91	b.b2x5	6.77368	6	3	7
92	b.b3x3	3.546	4	0	8
93	b.l3x2	4.42186	5	3	9
94	b.b4x2	5.28626	4	0	8
95	b.b4x3	4.63465	4	11	7
96	b.b4x4	8.3911	4	3	8
97	b.b4x5	4.05762	4	16	7
98	b.b4x6	8.87704	7	3	9
99	b.b5x2	5.47848	4	0	7
100	b.b5x3	6.42695	6	3	9
101	b.b5x5	5.1558	4	16	5
102	b.b5x7	6.12117	4	0	7
103	b.l5x1	4.08213	5	11	8
104	b.l5x5	8.11843	6	1	9
105	b.b6x5	4.42161	4	0	6
106	b.l6x5	5.85294	4	14	4
107	b.b7x1	5.66832	5	14	4
108	b.b7x4	3.65361	4	11	8
109	b.l7x4	2.29556	4	0	9
110	b.b8x4	5.44251	5	11	6
111	b.b9x3	3.6015	5	11	6
112	b.l9x3	6.30074	6	1	9
113	b.l9x6	4.57152	8	1	8
114	b.b10x5	4.42618	6	0	9
115	b.l10x1	3.86619	4	0	3
116	b.b11x4	5.11622	4	1	9
117	b.l11x2	6.52364	5	1	9
118	b.b12x6	7.67052	7	1	8
119	b.b13x7	7.55833	5	5	7
120	b.l13x3	7.1822	6	5	9
121	b.l13x6	4.71583	5	1	9
122	b.l13x7	4.28912	4	5	9
123	b.b14x3	4.4767	4	5	5
124	b.b15x1	6.22673	5	5	9
125	b.b15x2	6.45173	4	4	6
126	b.l15x1	4.39198	5	1	7
127	b.l15x2	4.49463	5	5	9
128	b.b16x4	8.70679	5	5	6
129	b.b16x5	4.20656	5	0	5
130	b.b16x6	8.50516	6	5	8
131	b.b17x4	5.06606	4	15	5
132	b.b17x7	7.76827	4	4	8
133	b.l17x3	7.72022	7	4	9
134	b.l17x6	6.29647	4	1	9
135	b.b18x3	4.86089	4	4	8
136	b.b18x5	5.48138	4	0	5
137	b.l18x1	5.29881	8	12	6
138	b.l18x2	5.61948	4	12	7
139	b.l18x3	6.89243	4	12	5
140	b.b19x2	6.50547	6	4	6
141	b.b19x4	6.39918	4	4	8
142	b.l19x2	5.53784	5	4	9
143	b.b20x4	8.4947	6	4	8
144	b.b20x6	6.7568	6	4	6
145	b.b20x7	3.83884	4	0	9
146	b.l20x2	5.33669	4	0	9
147	b.b21x1	6.74386	5	4	7
148	b.b21x2	2.28012	4	0	6
149	b.b21x4	3.57609	4	0	5
150	b.b21x5	5.00675	4	0	4
151	b.b21x7	5.32167	6	0	5
152	b.l21x2	4.84686	4	0	4
153	b.l21x7	3.73292	4	1	5
154	b.b22x5	5.67253	5	12	7
155	b.l22x5	6.6359	5	20	9
156	b.b23x6	6.37992	7	1	7
157	b.l23x1	7.45385	4	1	6
158	b.b24x4	7.01305	4	1	6
159	b.b24x6	5.69445	4	1	8
160	b.l24x2	4.06055	4	0	6
161	b.l24x3	4.72087	4	0	5
162	b.b25x3	5.89095	4	1	5
163	b.l25x3	7.92324	5	10	9
164	b.l25x6	11.4171	4	1	8
165	b.b26x3	3.85836	4	0	6
166	b.l28x1	10.5636	7	1	9
167	b.l28x2	7.23911	4	10	9
168	b.b28x3	3.90067	5	3	7
169	b.b28x4	7.23638	4	10	6
170	b.b28x6	7.74905	6	10	9
171	g.h1x8	1.89349	4	0	7
172	g.h2x11	9.18553	4	12	6
173	g.ctx3	6.10989	5	0	9
174	g.ctx6	3.53675	4	0	6
175	g.ctx14	5.14106	4	3	9
176	g.ctx15	6.33283	4	3	9
177	g.ctx16	4.21508	9	3	8
178	Lig	9.82175	27	2	0
179	b.lhb1x11	2.87367	5	10	0
180	g.h1x1	0.550735	5	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	2x50	7x46	14.3156	6.00029	Yes	No	0	9	9
2	3x36	Lig	35.1662	3.51356	No	Yes	2	7	0
3	3x36	6x48	35.4387	4.8784	No	Yes	0	7	8
4	6x44	6x48	40.8036	7.35863	No	Yes	0	9	8
5	3x43	6x44	46.2391	3.30674	Yes	No	0	8	9
6	3x43	7x53	68.023	4.63984	Yes	Yes	6	8	9
7	2x43	7x54	10.9117	2.21684	No	Yes	0	8	6
8	2x46	2x50	10.1985	4.08905	Yes	Yes	6	9	9
9	2x46	3x43	10.7067	3.51158	Yes	Yes	6	9	8
10	2x50	7x49	10.1247	4.47171	Yes	Yes	6	9	9
11	3x43	7x49	10.931	3.0329	Yes	Yes	6	8	9
12	3x50	7x53	37.688	4.82122	Yes	Yes	6	9	9
13	3x50	5x58	51.5581	6.45367	Yes	Yes	6	9	9
14	3x47	5x58	90.6405	6.67238	No	Yes	6	9	9
15	6x40	7x53	37.5417	5.28088	No	Yes	0	8	9
16	5x58	6x40	38.1733	3.08259	Yes	No	0	9	8
17	3x47	5x57	90.8923	2.72872	No	No	0	9	8
18	3x51	5x57	91.1253	7.66407	No	No	0	8	8
19	3x51	3x55	91.4743	6.99398	No	No	0	8	7
20	3x55	5x64	92.1631	4.72193	No	No	0	7	5
21	5x64	5x68	92.6265	2.39996	No	No	0	5	6
22	5x68	G.H5.13	92.9734	3.30835	No	Yes	0	6	8
23	G.H5.13	G.S6.02	93.1674	6.34288	Yes	Yes	0	8	7
24	G.H5.10	G.S6.02	94.7351	4.27069	No	Yes	0	6	7
25	G.H5.10	G.S5.03	94.8495	3.44675	No	Yes	0	6	8
26	G.S5.03	G.S5.05	94.4003	3.26165	Yes	Yes	7	8	9
27	G.H1.04	G.S5.05	49.6946	3.33796	No	Yes	7	7	9
28	G.H1.04	G.S5.07	49.6981	3.9778	No	Yes	7	7	9
29	G.S5.07	G.s5hg.01	100	2.62895	Yes	No	0	9	9
30	G.s4h3.02	G.s5hg.01	99.6761	4.59981	No	No	0	9	9
31	G.HG.07	G.s4h3.02	99.7239	4.05058	No	No	0	9	9
32	G.HG.07	G.s4h3.04	99.3693	6.46253	No	Yes	13	9	8
33	G.HG.04	G.s4h3.04	30.6151	4.6322	Yes	Yes	0	9	8
34	G.HG.04	G.s4h3.01	30.3045	10.177	Yes	No	0	9	7
35	G.S5.06	G.s4h3.01	30.2575	7.88823	No	No	0	8	7
36	G.S5.04	G.S5.06	30.058	3.03065	Yes	No	0	9	8
37	G.H3.09	G.S5.04	17.1052	3.62361	Yes	Yes	8	9	9
38	G.H3.09	G.S5.02	81.7157	4.45843	Yes	No	0	9	6
39	G.S4.02	G.S5.02	80.4243	2.90252	Yes	No	0	8	6
40	G.H3.18	G.S4.02	79.9557	8.21985	Yes	Yes	17	9	8
41	G.H3.15	G.H3.18	79.5395	4.68257	No	Yes	0	8	9
42	G.H3.15	G.H3.17	79.3264	4.42169	No	Yes	0	8	5
43	G.H3.17	b.l28x1	54.8913	3.51765	Yes	Yes	1	5	9
44	b.b26x1	b.l28x1	58.202	5.33222	No	Yes	0	9	9
45	b.b26x1	b.b26x2	57.975	3.23786	No	No	0	9	7
46	b.b26x2	b.b2x3	57.7487	5.20923	No	No	0	7	6
47	b.b2x3	b.b3x2	33.9052	3.97435	No	No	3	6	5
48	b.b3x2	b.b4x6	33.7848	4.51565	No	Yes	3	5	9
49	G.S5.05	G.s6h5.01	49.6526	3.61146	Yes	No	7	9	9
50	G.S5.07	G.s6h5.01	50.0963	6.08183	Yes	No	7	9	9
51	G.HG.15	G.s4h3.04	35.0037	2.87471	No	Yes	0	7	8
52	G.HG.15	G.hgh4.02	35.0008	3.16741	No	Yes	0	7	7
53	G.H3.06	G.hgh4.02	69.7769	5.15079	Yes	Yes	0	6	7
54	G.H3.06	G.h4s6.01	34.6085	3.09755	Yes	No	0	6	4
55	G.H3.09	G.h4s6.01	34.345	3.94263	Yes	No	0	9	4
56	G.hgh4.01	G.s4h3.04	34.7024	3.78755	No	Yes	0	6	8
57	G.hgh4.01	G.hgh4.02	34.7083	7.58766	No	Yes	0	6	7
58	G.H3.06	G.H4.15	34.9181	3.4302	Yes	Yes	0	6	8
59	G.H3.09	G.H4.15	34.3623	3.67393	Yes	Yes	8	9	8
60	b.b4x6	b.l1x3	13.3249	4.41888	Yes	Yes	3	9	9
61	b.l1x3	b.l3x2	12.6206	3.04697	Yes	Yes	3	9	9
62	b.b4x2	b.l3x2	11.4138	5.77038	Yes	Yes	0	8	9
63	b.b4x2	b.b5x8	21.8786	2.81531	Yes	No	0	8	5
64	b.b5x7	b.b5x8	21.3963	3.25923	Yes	No	0	7	5
65	b.b4x4	b.b4x6	11.8778	13.99	Yes	Yes	3	8	9
66	G.HN.47	b.b4x4	11.6707	2.99139	No	Yes	0	6	8
67	G.HN.47	b.b4x2	11.43	5.2733	No	Yes	0	6	8
68	G.S4.04	G.S5.04	13.1668	2.88501	Yes	Yes	8	9	9
69	G.H3.08	G.S4.04	12.5562	5.39932	No	Yes	0	9	9
70	G.H2.04	G.H3.08	12.5296	3.65445	Yes	No	0	9	9
71	G.H2.04	G.H2.07	12.5286	5.1326	Yes	Yes	0	9	9
72	G.H2.07	b.l9x6	17.7461	2.99681	Yes	Yes	1	9	8
73	G.H3.17	b.l25x6	23.1964	3.05037	Yes	Yes	1	5	8
74	b.l23x1	b.l25x6	24.7577	18.2321	Yes	Yes	1	6	8
75	b.l21x7	b.l23x1	24.2963	4.96042	Yes	Yes	1	5	6
76	b.b23x6	b.l21x7	22.8872	3.2819	Yes	Yes	1	7	5
77	b.b23x6	b.b24x6	19.849	7.48712	Yes	Yes	1	7	8
78	b.b21x7	b.b24x6	19.4461	7.39957	Yes	Yes	0	5	8
79	b.b2x3	b.b2x5	23.6175	4.33801	No	Yes	3	6	7
80	b.b2x5	b.l27x1	14.9746	12.3851	Yes	No	3	7	8
81	b.l27x1	b.l27x3	14.5071	5.52015	No	No	3	8	7
82	b.l27x3	b.l27x5	14.287	6.29406	No	No	0	7	5
83	b.l27x5	g.ctx4	14.6866	4.36725	No	No	0	5	7
84	g.ctx3	g.ctx4	14.2265	4.03974	Yes	No	0	9	7
85	b.b5x7	b.b8x4	10.7221	7.14143	Yes	Yes	0	7	6
86	3x46	3x50	10.2844	5.73523	Yes	Yes	6	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
1x39	2x57	4.5996	2	Yes	Yes	7	7	2	2
1x39	7x38	2.94538	2	Yes	Yes	7	5	2	1
2x56	3x32	4.60584	0	No	No	6	5	2	1
2x57	7x42	8.36232	2	Yes	Yes	7	7	2	1
2x60	7x38	3.37032	2	No	Yes	6	5	1	1
2x60	7x42	3.71458	2	No	Yes	6	7	1	1
2x63	E1x50	4.80855	2	No	Yes	4	8	1	2
2x64	7x35	3.95185	2	No	No	5	4	1	2
E1x49	E2	5.82602	2	No	Yes	5	3	2	1
E1x50	E2	3.14279	2	Yes	Yes	8	3	2	1
3x22	E2	5.03455	2	No	Yes	3	3	2	1
3x32	Lig	6.42477	2	No	Yes	5	0	1	0
3x33	Lig	5.70603	2	Yes	Yes	4	0	1	0
3x36	6x48	4.8784	2	No	Yes	7	8	1	2
3x36	Lig	3.51356	2	No	Yes	7	0	1	0
E2	E2	61.46	2	Yes	Yes	3	3	1	1
E2	E2x51	11.9393	2	Yes	No	3	4	1	1
E2	E2x52	3.11788	2	Yes	No	3	4	1	1
5x32	E2	2.87557	2	No	Yes	3	3	2	1
5x35	E2	4.37582	2	No	Yes	1	3	2	1
5x36	E2	7.73164	2	No	Yes	4	3	2	1
5x43	Lig	4.89137	2	No	Yes	5	0	1	0
6x48	6x52	3.61464	0	Yes	Yes	8	7	2	2
6x51	6x52	2.73229	2	No	Yes	6	7	1	2
6x51	6x55	6.41795	2	No	No	6	5	1	1
6x51	Lig	5.99661	2	No	Yes	6	0	1	0
6x54	7x34	4.95763	0	No	No	5	4	2	1
6x55	Lig	7.71228	2	No	Yes	5	0	1	0
6x61	E3	4.95784	0	No	Yes	2	2	2	1
E3	E3	10.0578	2	Yes	Yes	2	2	1	1
7x30	E3	3.16889	0	No	Yes	3	2	2	1
7x34	7x38	3.21863	2	No	Yes	4	5	1	1
7x34	Lig	11.2111	2	No	Yes	4	0	1	0
7x38	7x42	5.17011	2	Yes	Yes	5	7	1	1
7x38	Lig	4.07881	2	Yes	Yes	5	0	1	0
7x42	Lig	3.5429	2	Yes	Yes	7	0	1	0
Lig	NT	3.24628	2	Yes	No	0	7	0	1
2x53	7x42	4.65951	0	No	Yes	7	7	2	1
2x60	Lig	7.07586	2	No	Yes	6	0	1	0
2x63	Lig	6.83508	2	No	Yes	4	0	1	0
3x29	Lig	4.18242	2	No	Yes	4	0	1	0
E2	Lig	22.544	2	Yes	Yes	3	0	1	0
6x58	Lig	7.63529	0	No	Yes	3	0	1	0
3x33	3x37	4.53928	2	Yes	Yes	4	6	1	2
E2x51	Lig	4.72227	2	No	Yes	4	0	1	0
5x43	6x52	2.82915	2	No	Yes	5	7	1	2
E2x52	Lig	3.76737	2	No	Yes	4	0	1	0
4x64	E2	10.1462	2	No	Yes	5	3	2	1
7x31	Lig	4.73734	2	No	Yes	4	0	1	0
2x64	Lig	3.45459	2	No	Yes	5	0	1	0
5x32	5x35	3.68937	2	No	No	3	1	2	2
E3	Lig	12.8782	2	Yes	Yes	2	0	1	0
1x39	7x42	4.03083	2	Yes	Yes	7	7	2	1
7x27	Lig	3.44889	0	No	Yes	3	0	1	0
E1	Lig	4.27952	0	No	Yes	0	0	1	0
3x28	3x29	3.18904	0	No	No	5	4	2	1
3x29	4x65	7.26694	2	No	No	4	0	1	2
3x33	4x61	4.93035	2	Yes	No	4	5	1	2
4x65	E2x52	5.11551	0	No	No	0	4	2	1
3x33	4x57	2.72769	2	Yes	No	4	6	1	2
7x26	E3	2.42474	2	No	Yes	0	2	2	1
6x57	E3	2.34573	0	No	Yes	5	2	2	1
5x31	E2	1.88038	0	No	Yes	4	3	2	1
1x32	2x64	1.86285	0	Yes	No	4	5	2	1
1x30	1x31	1.84654	2	No	No	3	4	1	2
2x63	2x67	1.52303	2	No	No	4	2	1	2
1x30	Lig	1.49231	2	No	Yes	3	0	1	0
7x28	Lig	1.04788	0	No	Yes	1	0	1	0
7x23	E3	0.941667	2	No	Yes	0	2	2	1
1x25	Lig	0.685769	0	No	Yes	0	0	1	0
7x24	E3	0.624835	2	No	Yes	0	2	2	1
5x28	E2	0.54547	2	No	Yes	0	3	2	1
1x27	7x31	0.384231	0	No	No	0	4	2	1
5x27	E2	0.298974	2	No	Yes	0	3	2	1
1x23	NT	0.0753846	0	No	No	0	7	2	1
1x23	7x24	0.0753846	0	No	No	0	0	2	2
1x22	E3	0.0607692	0	No	Yes	0	2	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
75.00	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
75.00	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
64.29	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
63.33	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
62.07	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
61.54	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
61.54	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
61.54	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
61.29	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
61.29	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
60.00	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
59.26	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
59.26	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
58.06	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
57.69	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
57.69	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
57.58	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
57.14	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
57.14	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
56.67	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
55.88	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
55.56	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
55.17	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
55.17	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
55.17	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
55.17	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
54.84	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
54.84	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
53.85	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
53.85	Consensus	orexin_on	Orthosteric Ligand	ox2_on
53.57	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
53.33	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
53.33	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
53.33	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
53.33	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
53.12	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
53.12	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
51.85	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
51.85	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
51.85	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
51.72	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
51.72	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
51.72	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
51.72	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
51.61	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
51.61	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
51.61	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
51.61	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
51.61	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
51.61	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
51.43	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
51.43	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
50.00	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
50.00	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
50.00	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
50.00	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
50.00	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
50.00	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
50.00	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
50.00	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
50.00	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
50.00	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
50.00	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
50.00	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
50.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
50.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
50.00	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
50.00	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
50.00	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
50.00	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
48.48	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
48.48	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
48.48	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
48.39	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
48.39	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
48.39	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
48.39	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.39	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.39	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.28	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
48.28	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
48.28	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
48.28	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
48.28	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
48.15	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
48.15	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
47.22	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
47.06	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
47.06	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
46.88	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
46.88	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
46.67	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
46.43	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
46.43	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
46.43	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.43	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
46.43	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
46.43	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
46.43	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
46.43	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
46.43	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
46.43	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
46.43	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
46.15	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
46.15	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
46.15	Single	8E0G	BU72	8E0G-μ-BU72
46.15	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.15	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
46.15	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
46.15	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
45.45	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
45.16	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
45.16	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
44.83	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
44.83	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
44.83	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
44.83	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
44.83	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
44.83	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
44.83	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
44.83	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
44.83	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
44.44	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
44.44	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
44.44	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
44.44	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
44.44	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.44	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
44.44	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
44.44	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
44.44	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.44	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
44.44	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
44.44	Consensus	dp_off	Orthosteric Ligand	dp2_off
44.44	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
44.44	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
44.12	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
44.00	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
44.00	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
44.00	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
44.00	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
44.00	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
44.00	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
43.75	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
43.75	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
43.75	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
43.75	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.75	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
43.75	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.75	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.33	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
43.33	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
43.33	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
43.33	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
43.33	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.33	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
43.33	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
42.86	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
42.86	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
42.86	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
42.86	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
42.86	Single	7EZC	UKA	7EZC-A_2A-UKA
42.86	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
42.86	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
42.86	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
42.86	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
42.42	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
42.42	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
42.42	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
42.42	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
42.42	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
42.31	Single	5C1M	BU72	5C1M-μ-BU72
42.31	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
42.31	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
42.31	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
42.31	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
42.31	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
42.31	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
41.94	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
41.94	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
41.94	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
41.94	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
41.94	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
41.94	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
41.94	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
41.94	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
41.94	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
41.67	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
41.67	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
41.38	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
41.38	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
41.38	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
41.38	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.38	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
41.38	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
41.38	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
41.38	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
41.38	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
41.38	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
41.38	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
41.38	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
41.18	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.18	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
41.18	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
40.74	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
40.74	Single	6OS1	TRV026	6OS1-AT₁-TRV026
40.74	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
40.74	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
40.74	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
40.74	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.74	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
40.74	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
40.74	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
40.74	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
40.74	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
40.74	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
40.74	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
40.74	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
40.74	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
40.74	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
40.74	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
40.62	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
40.62	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
40.62	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
40.62	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
40.62	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.54	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
40.00	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
40.00	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
40.00	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
40.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
40.00	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
40.00	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
40.00	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
40.00	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
40.00	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
40.00	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
40.00	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
40.00	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
39.47	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
39.39	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
39.39	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
39.39	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
39.39	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
39.29	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
39.29	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
39.29	Single	6OS2	TRV026	6OS2-AT₁-TRV026
39.29	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
39.29	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
39.29	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
39.29	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
39.29	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
39.29	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
39.29	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
39.29	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
39.29	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
39.29	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
39.29	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
39.29	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
39.29	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
39.29	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
39.29	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
39.29	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
39.29	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
38.71	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
38.71	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
38.71	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
38.71	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
38.71	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
38.71	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
38.46	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
38.46	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
38.46	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
38.46	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
38.46	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
38.46	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
38.46	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
38.46	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
38.46	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
38.46	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
38.46	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
38.46	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
38.46	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
38.24	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
38.24	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
37.93	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
37.93	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
37.93	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
37.93	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
37.93	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
37.93	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
37.93	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
37.93	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
37.93	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
37.93	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
37.93	Consensus	endothelin_off	Orthosteric Ligand	etb_off
37.93	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
37.93	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.93	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
37.93	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
37.93	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
37.50	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
37.50	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
37.50	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
37.50	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
37.50	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
37.50	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.50	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
37.50	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
37.50	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
37.50	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
37.50	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.50	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
37.14	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
37.14	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
37.04	Single	5N2S	PSB36	5N2S-A₁-PSB36
37.04	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
37.04	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
37.04	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
37.04	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
37.04	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
37.04	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
37.04	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
37.04	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
37.04	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
37.04	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
37.04	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
37.04	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
37.04	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
37.04	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
37.04	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
37.04	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
36.67	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
36.67	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
36.67	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.67	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
36.67	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
36.67	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
36.67	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
36.67	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
36.67	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
36.67	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
36.67	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.67	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.36	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
36.36	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.36	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
36.36	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
36.36	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
36.00	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
36.00	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
36.00	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
36.00	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.00	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
36.00	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
36.00	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
36.00	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
35.90	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
35.71	Single	2YDV	NECA	2YDV-A_2A-NECA
35.71	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
35.71	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
35.71	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
35.71	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
35.71	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
35.71	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
35.71	Single	5G53	NECA	5G53-A_2A-NECA-Gs
35.71	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
35.71	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
35.71	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
35.71	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
35.71	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
35.71	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
35.71	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
35.71	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
35.71	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
35.71	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
35.71	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
35.71	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
35.71	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
35.71	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.71	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
35.71	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
35.71	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
35.71	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
35.71	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
35.71	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
35.71	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
35.71	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
35.71	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
35.71	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
35.71	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
35.71	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
35.71	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
35.71	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
35.71	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
35.71	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
35.71	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
35.48	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
35.48	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
35.48	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
35.48	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
35.48	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
35.48	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
35.48	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
35.29	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
35.29	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
35.14	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
34.62	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
34.62	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
34.62	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
34.62	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
34.62	Single	6TPG	EMPA	6TPG-OX₂-EMPA
34.62	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
34.62	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.62	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
34.62	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
34.62	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
34.62	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
34.62	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
34.62	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
34.62	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
34.62	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
34.62	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
34.62	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
34.62	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
34.62	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
34.62	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
34.62	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
34.62	Consensus	hcar_on	Orthosteric Ligand	hca_on
34.62	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
34.62	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
34.48	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
34.48	Single	4LDE	BI167107	4LDE-β₂-BI167107
34.48	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
34.48	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
34.48	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
34.48	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
34.48	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
34.48	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
34.48	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
34.48	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
34.48	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
34.48	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
34.48	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
34.48	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
34.48	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.48	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
34.48	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
34.48	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
34.48	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
34.48	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
34.48	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
34.48	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
34.48	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
34.48	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
34.48	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
34.48	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
34.48	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
34.48	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
34.48	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
34.48	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
34.48	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
34.48	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
34.48	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
34.48	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.48	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
34.48	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
34.48	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.38	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
34.38	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
34.29	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
34.09	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
33.33	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
33.33	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
33.33	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
33.33	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
33.33	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
33.33	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
33.33	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
33.33	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
33.33	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
33.33	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
33.33	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
33.33	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
33.33	Single	6D27	CAY10471	6D27-DP₂-CAY10471
33.33	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
33.33	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
33.33	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
33.33	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
33.33	Single	6PS1	Timolol	6PS1-β₂-Timolol
33.33	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
33.33	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
33.33	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
33.33	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
33.33	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
33.33	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
33.33	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
33.33	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
33.33	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
33.33	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
33.33	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
33.33	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
33.33	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
33.33	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
33.33	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
33.33	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
33.33	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
33.33	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
33.33	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
33.33	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
33.33	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
33.33	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
33.33	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
33.33	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
33.33	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
33.33	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
33.33	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
33.33	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
33.33	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
33.33	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
33.33	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
33.33	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
33.33	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
33.33	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
33.33	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
33.33	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
33.33	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
33.33	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
33.33	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
33.33	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
33.33	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
33.33	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
33.33	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
33.33	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
33.33	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
33.33	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
33.33	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
33.33	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
33.33	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
33.33	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
33.33	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
32.43	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
32.43	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
32.35	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
32.35	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
32.35	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
32.35	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
32.35	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
32.26	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
32.26	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
32.26	Single	6PT3	DPI-287	6PT3-δ-DPI-287
32.26	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
32.26	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
32.26	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
32.26	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
32.26	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
32.26	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
32.26	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
32.14	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
32.14	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
32.14	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
32.14	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
32.14	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
32.14	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
32.14	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
32.14	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
32.14	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
32.14	Single	5WQC	EMPA	5WQC-OX₂-EMPA
32.14	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
32.14	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
32.14	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
32.14	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
32.14	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
32.14	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
32.14	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
32.14	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
32.14	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
32.14	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
32.14	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
32.14	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
32.14	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
32.14	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
32.14	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
32.14	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
32.14	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
32.14	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
32.14	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
32.14	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
32.14	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
32.14	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
32.14	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
32.14	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
32.14	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
32.14	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
32.14	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
32.14	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
32.14	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
32.14	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
32.14	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
32.14	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
32.14	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
32.14	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
32.14	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
32.14	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
32.14	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
32.00	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
32.00	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
32.00	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
32.00	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
32.00	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
32.00	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
32.00	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
32.00	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
32.00	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
32.00	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
32.00	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
31.71	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
31.58	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
31.43	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
31.43	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
31.43	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
31.43	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
31.25	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
31.25	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
31.03	Single	3P0G	BI167107	3P0G-β₂-BI167107
31.03	Single	4DJH	JDTic	4DJH-κ-JDTic
31.03	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
31.03	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
31.03	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
31.03	Single	5X93	K-8794	5X93-ET_B-K-8794
31.03	Single	5XR8	AM841	5XR8-CB₁-AM841
31.03	Single	5XRA	AM11542	5XRA-CB₁-AM11542
31.03	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
31.03	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
31.03	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
31.03	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
31.03	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
31.03	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
31.03	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
31.03	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
31.03	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
31.03	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
31.03	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
31.03	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
31.03	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
31.03	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
31.03	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
31.03	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
31.03	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.03	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
31.03	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
31.03	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
31.03	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
31.03	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
31.03	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
31.03	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
31.03	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
31.03	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
31.03	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
31.03	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
31.03	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
31.03	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
31.03	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
31.03	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
31.03	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
31.03	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
31.03	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
31.03	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
31.03	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
31.03	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
31.03	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
30.77	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
30.77	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
30.77	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
30.77	Single	5WS3	EMPA	5WS3-OX₂-EMPA
30.77	Single	6AKX	A4R	6AKX-CCR5-A4R
30.77	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
30.77	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
30.77	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
30.77	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
30.77	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
30.77	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
30.77	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
30.77	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
30.77	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
30.77	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
30.77	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
30.77	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
30.77	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.77	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.77	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.77	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
30.77	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
30.77	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
30.77	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
30.77	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
30.77	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
30.77	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
30.77	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.77	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
30.77	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
30.77	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
30.77	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
30.56	Single	6FJ3	PTH	6FJ3-PTH1-PTH
30.56	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
30.56	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
30.56	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
30.56	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
30.56	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
30.30	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
30.30	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
30.30	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
30.30	Consensus	sst_off	Orthosteric Ligand	sst2_off
30.23	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
30.00	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
30.00	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
30.00	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
30.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
30.00	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
30.00	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
30.00	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
30.00	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
30.00	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
30.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
30.00	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
30.00	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
30.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
30.00	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
30.00	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.00	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
30.00	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
30.00	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
30.00	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
30.00	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
30.00	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
30.00	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
30.00	Consensus	blt_off	Orthosteric Ligand	blt1_off
30.00	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
30.00	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
30.00	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
30.00	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
30.00	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
30.00	Consensus	nts_on	Orthosteric Ligand	nts1_on
30.00	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
29.73	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
29.63	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
29.63	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
29.63	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
29.63	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
29.63	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
29.63	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
29.63	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
29.63	Single	6IQL	L745870	6IQL-D₄-L745870
29.63	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
29.63	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
29.63	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
29.63	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
29.63	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
29.63	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
29.63	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
29.63	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
29.63	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
29.63	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
29.63	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
29.63	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
29.63	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
29.63	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
29.63	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.63	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
29.63	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
29.63	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
29.63	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
29.63	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
29.63	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
29.63	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
29.63	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
29.63	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
29.63	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
29.63	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
29.63	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
29.63	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
29.63	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
29.63	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.63	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
29.63	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
29.63	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
29.63	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
29.63	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
29.63	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
29.63	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
29.63	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
29.63	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
29.63	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
29.63	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
29.63	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
29.55	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
29.41	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
29.41	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
29.41	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
29.27	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
29.27	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
29.03	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
29.03	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
29.03	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
29.03	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
29.03	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
29.03	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
29.03	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
29.03	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
28.95	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
28.95	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
28.95	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
28.57	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
28.57	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
28.57	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
28.57	Single	3EML	ZM241385	3EML-A_2A-ZM241385
28.57	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
28.57	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
28.57	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
28.57	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
28.57	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
28.57	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
28.57	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
28.57	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
28.57	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
28.57	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
28.57	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
28.57	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
28.57	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
28.57	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
28.57	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
28.57	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
28.57	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
28.57	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
28.57	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
28.57	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
28.57	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
28.57	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
28.57	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
28.57	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
28.57	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
28.57	Single	7BU7	BI167107	7BU7-β₁-BI167107
28.57	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
28.57	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
28.57	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
28.57	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
28.57	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
28.57	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
28.57	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
28.57	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
28.57	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
28.57	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
28.57	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
28.57	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
28.57	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
28.57	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
28.57	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
28.57	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
28.57	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
28.57	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
28.57	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
28.57	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
28.57	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
28.57	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
28.57	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
28.57	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
28.57	Consensus	cck_off	Orthosteric Ligand	ccka_off
28.57	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
28.57	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
28.57	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
28.57	Consensus	tar_on	Orthosteric Ligand	ta1_on
28.12	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
28.12	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
28.12	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
28.00	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
28.00	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
28.00	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
28.00	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
28.00	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
28.00	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
27.78	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
27.78	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
27.59	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
27.59	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
27.59	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
27.59	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
27.59	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
27.59	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
27.59	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
27.59	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
27.59	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
27.59	Single	6PS6	Timolol	6PS6-β₂-Timolol
27.59	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
27.59	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
27.59	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
27.59	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
27.59	Single	7C4S	S1P	7C4S-S1P₃-S1P
27.59	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
27.59	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
27.59	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
27.59	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
27.59	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
27.59	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
27.59	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
27.59	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
27.59	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.59	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.59	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
27.59	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
27.59	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
27.59	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
27.59	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
27.59	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
27.59	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
27.59	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
27.50	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
27.50	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
27.50	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
27.27	Single	7QA8	Peptide	7QA8-STE2-Peptide
27.27	Single	7QA8	Peptide	7QA8-STE2-Peptide
27.27	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
27.27	Consensus	class-d_off	Orthosteric Ligand	ste2_off
27.27	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
27.03	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
27.03	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
27.03	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
27.03	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
26.92	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
26.92	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
26.92	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
26.92	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
26.92	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
26.92	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
26.92	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
26.92	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
26.92	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
26.92	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
26.92	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
26.92	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
26.92	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
26.92	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
26.92	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
26.92	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
26.92	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
26.67	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
26.67	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
26.67	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
26.67	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
26.67	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
26.67	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
26.67	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
26.67	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
26.67	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
26.67	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
26.67	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
26.67	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
26.67	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
26.67	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
26.67	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
26.67	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
26.67	Consensus	histamine_off	Orthosteric Ligand	h1_off
26.47	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
26.47	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
26.47	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
26.47	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
26.47	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
26.47	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
26.47	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
26.32	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
26.32	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
26.32	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
26.32	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
26.32	Consensus	go_class-b1	Orthosteric Ligand	go_crf
26.32	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
26.32	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
26.19	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
26.19	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
25.93	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
25.93	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
25.93	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
25.93	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
25.93	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
25.93	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
25.93	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
25.93	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
25.93	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
25.93	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
25.93	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
25.93	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
25.93	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
25.93	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
25.93	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
25.93	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
25.93	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
25.93	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
25.93	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
25.93	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
25.93	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
25.93	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
25.93	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
25.93	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
25.93	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
25.93	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
25.93	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
25.93	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
25.93	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.93	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
25.93	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
25.93	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
25.93	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
25.93	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.93	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.93	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.93	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.93	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
25.93	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
25.93	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
25.93	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.93	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
25.93	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
25.93	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
25.93	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
25.93	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
25.93	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
25.81	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
25.81	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
25.81	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
25.81	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
25.81	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
25.81	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
25.81	Consensus	gi_class-f	Other Ligand	gi_frizzled
25.81	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
25.64	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
25.64	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
25.64	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
25.64	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
25.64	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
25.58	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
25.58	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
25.00	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
25.00	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
25.00	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
25.00	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
25.00	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
25.00	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
25.00	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
25.00	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
25.00	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
25.00	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
25.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
25.00	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
25.00	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
25.00	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
25.00	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
25.00	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
25.00	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
25.00	Single	6VI4	JDTic	6VI4-κ-JDTic
25.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
25.00	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
25.00	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
25.00	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
25.00	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
25.00	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
25.00	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
25.00	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
25.00	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
25.00	Single	7T32	ZM241385	7T32-A_2A-ZM241385
25.00	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
25.00	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
25.00	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
25.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
25.00	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
25.00	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
25.00	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
25.00	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
25.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
25.00	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
25.00	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
25.00	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
25.00	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
25.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
25.00	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
25.00	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
25.00	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
25.00	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
25.00	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
25.00	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
25.00	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
25.00	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
25.00	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
25.00	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
25.00	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
24.44	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
24.39	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
24.39	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
24.32	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
24.32	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
24.32	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
24.32	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
24.24	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
24.24	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
24.24	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
24.24	Consensus	class-d_off	Orthosteric Ligand	ste2_off
24.24	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
24.14	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
24.14	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
24.14	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
24.14	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
24.14	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
24.14	Single	5UEN	DU172	5UEN-A₁-DU172
24.14	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
24.14	Single	6GPS	MK0812	6GPS-CCR2-MK0812
24.14	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
24.14	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
24.14	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
24.14	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
24.14	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
24.14	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
24.14	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
24.14	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
24.14	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
24.14	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
24.14	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
24.14	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
24.14	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
24.14	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
24.14	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
24.14	Consensus	a2_off	Orthosteric Ligand	a2a_off
24.14	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
24.14	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
24.14	Consensus	blt_on	Orthosteric Ligand	blt1_on
24.14	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
24.14	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
24.14	Consensus	leuko_on	Orthosteric Ligand	blt_on
24.14	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
24.14	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
24.00	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
24.00	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
24.00	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
23.81	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
23.81	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
23.81	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
23.68	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
23.68	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
23.68	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
23.68	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
23.68	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
23.68	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
23.68	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
23.53	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
23.53	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
23.33	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
23.33	Single	6GPX	MK0812	6GPX-CCR2-MK0812
23.33	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
23.33	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
23.33	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
23.33	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
23.33	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
23.33	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
23.33	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
23.33	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
23.33	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
23.33	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
23.08	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
23.08	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
23.08	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
23.08	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
23.08	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
23.08	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
23.08	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
23.08	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
23.08	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
23.08	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
23.08	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
22.92	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
22.86	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
22.58	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
22.58	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
22.58	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
22.58	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
22.58	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
22.58	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
22.58	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
22.58	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
22.58	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
22.58	Single	7W41	PD176252	7W41-BB₂-PD176252
22.58	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
22.58	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
22.58	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
22.58	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.58	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
22.58	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
22.58	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
22.58	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
22.58	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
22.58	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
22.58	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
22.58	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
22.58	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
22.58	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
22.50	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
22.50	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
22.50	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
22.50	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
22.22	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
22.22	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
22.22	Single	6HLL	CP99994	6HLL-NK₁-CP99994
22.22	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
22.22	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
22.22	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
22.22	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
22.22	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
22.22	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
22.22	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
22.22	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
22.22	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
22.22	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
22.22	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
22.22	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
22.22	Consensus	class-t_on	Orthosteric Ligand	taste2_on
22.22	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
22.22	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
22.22	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
22.22	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
21.95	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
21.95	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
21.88	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
21.88	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
21.88	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
21.88	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
21.88	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
21.88	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
21.88	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
21.88	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
21.88	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.88	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
21.88	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
21.88	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
21.88	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
21.88	Consensus	nts_off	Orthosteric Ligand	nts1_off
21.62	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
21.62	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
21.43	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
21.43	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
21.43	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
21.43	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
21.43	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
21.43	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
21.43	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
21.43	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
21.43	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
21.43	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.43	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
21.43	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
21.43	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
21.43	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
21.43	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
21.43	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
21.43	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
21.43	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
21.43	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
21.43	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
21.43	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.43	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
21.43	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
21.43	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
21.43	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.43	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.43	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
21.43	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
21.43	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
21.43	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.43	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
21.43	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
21.21	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
21.21	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
21.21	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
21.21	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.21	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.21	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
21.05	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
21.05	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
20.93	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
20.93	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
20.83	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
20.69	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
20.69	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
20.69	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
20.69	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
20.69	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
20.69	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
20.69	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
20.69	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
20.69	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.69	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.69	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.69	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
20.69	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
20.69	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
20.69	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.69	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
20.69	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.69	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
20.59	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
20.59	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.59	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
20.51	Consensus	class-d_on	Orthosteric Ligand	ste2_on
20.51	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
20.51	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
20.00	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
20.00	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
20.00	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
20.00	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
20.00	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
20.00	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
20.00	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
20.00	Single	6IIV	Daltroban	6IIV-TP-Daltroban
20.00	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
20.00	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
20.00	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
20.00	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
20.00	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
20.00	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
20.00	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
20.00	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
20.00	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
20.00	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
20.00	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
20.00	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
20.00	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
20.00	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
20.00	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
20.00	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
20.00	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
20.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
20.00	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
20.00	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
20.00	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
20.00	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
20.00	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
20.00	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
20.00	Consensus	hcar_off	Orthosteric Ligand	succinate_off
20.00	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
20.00	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
20.00	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
20.00	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
20.00	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
20.00	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
20.00	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
19.57	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
19.51	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
19.51	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
19.51	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
19.51	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
19.44	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
19.44	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
19.35	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
19.35	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
19.35	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
19.35	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
19.35	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
19.35	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
19.35	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
19.35	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
19.35	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
19.35	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
19.35	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
19.35	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
19.35	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.35	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
19.35	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
19.35	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
19.35	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
19.35	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
19.35	Consensus	ep_off	Orthosteric Ligand	ep4_off
19.35	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
19.35	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.35	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
19.35	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
19.35	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.23	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
19.23	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
19.23	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
19.23	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
19.23	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
19.23	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
19.23	Consensus	sensory_on	Orthosteric Ligand	opsin_on
18.92	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
18.75	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
18.75	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
18.75	Single	5V56	TC114	5V56-SMO-TC114
18.75	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
18.75	Single	6E59	L-760735	6E59-NK₁-L-760735
18.75	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
18.75	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
18.75	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
18.75	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
18.75	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
18.75	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
18.75	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
18.75	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
18.75	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
18.52	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
18.52	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
18.52	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
18.52	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
18.52	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
18.52	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
18.52	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
18.52	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
18.52	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
18.52	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
18.52	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
18.52	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
18.52	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
18.42	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
18.42	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
18.42	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
18.42	Consensus	class-d_on	Orthosteric Ligand	ste2_on
18.42	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
18.42	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
18.18	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
18.18	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
18.18	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
18.18	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
18.18	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
18.18	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
18.18	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
18.18	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
18.18	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
18.18	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
17.95	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
17.86	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
17.86	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
17.86	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
17.86	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
17.86	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
17.86	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
17.86	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
17.86	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.86	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.86	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.86	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
17.86	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
17.86	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
17.86	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
17.86	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
17.86	Consensus	go_protein	Orthosteric Ligand	go_chemokine
17.86	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
17.86	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
17.86	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
17.78	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
17.65	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
17.65	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
17.65	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
17.65	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.65	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
17.65	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.50	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
17.24	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
17.24	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
17.24	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
17.24	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
17.24	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
17.24	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
17.24	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
17.24	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
17.24	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
17.24	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
17.24	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
17.24	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
17.24	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
17.24	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
17.24	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
17.24	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.24	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
17.24	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
17.24	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
17.14	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
17.14	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.07	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
17.07	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
17.07	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
16.67	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
16.67	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
16.67	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
16.67	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
16.67	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
16.67	Single	6TPK	Retosiban	6TPK-OT-Retosiban
16.67	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
16.67	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
16.67	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
16.67	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
16.67	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
16.67	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
16.67	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
16.67	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
16.67	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
16.67	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
16.67	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
16.67	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
16.67	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
16.67	Consensus	sensory_off	Orthosteric Ligand	opsin_off
16.67	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
16.28	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
16.13	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
16.13	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
16.13	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
16.13	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
16.13	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
16.13	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
16.13	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
16.13	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.13	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
16.13	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
16.13	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
16.13	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
16.13	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.13	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.13	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
16.13	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
16.13	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
16.00	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
16.00	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
15.62	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
15.62	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
15.62	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
15.62	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
15.62	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
15.62	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
15.62	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
15.62	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
15.62	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
15.62	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
15.38	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
15.38	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
15.38	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
15.38	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
15.15	Single	5V57	TC114	5V57-SMO-TC114
15.15	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
15.15	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
15.15	Single	7EPE	NAM563	7EPE-mGlu-NAM563
15.15	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
15.15	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
15.15	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
14.81	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
14.81	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
14.81	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
14.71	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
14.71	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
14.71	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
14.71	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
14.71	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
14.29	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
14.29	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
14.29	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
14.29	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
14.29	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
14.29	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
14.29	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
14.29	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
14.29	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
14.29	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
14.29	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
14.29	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
14.29	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
14.29	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
13.95	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
13.95	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
13.89	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.89	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
13.79	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
13.79	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
13.79	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
13.79	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
13.79	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
13.79	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
13.79	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
13.79	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
13.79	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
13.79	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
13.79	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
13.79	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
13.79	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
13.79	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
13.79	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
13.79	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
13.73	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
13.51	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
13.51	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
13.33	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
13.33	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
13.33	Single	5U09	Taranabant	5U09-CB₁-Taranabant
13.33	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
13.33	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
13.33	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
13.33	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
13.33	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
13.33	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
13.33	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
13.33	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
13.33	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
13.33	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
13.33	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
13.33	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
13.33	Consensus	class-f_off	Orthosteric Ligand	smo_off
13.33	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
13.16	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.90	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
12.90	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
12.90	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
12.90	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
12.90	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.77	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
12.50	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
12.50	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
12.50	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
12.50	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
12.50	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.24	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
11.76	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
11.76	Single	7P2L	4YI	7P2L-mGlu₅-4YI
11.76	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
11.76	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.54	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
11.54	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
11.54	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.43	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.43	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.43	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
11.11	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
11.11	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
11.11	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
11.11	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
11.11	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
11.11	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
11.11	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
10.71	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
10.71	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
10.71	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
10.64	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
10.42	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
10.34	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
10.34	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
10.34	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
10.34	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
10.00	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
10.00	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
9.68	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.68	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
9.68	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
9.38	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
9.38	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
9.38	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
9.38	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
9.38	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
9.38	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
9.09	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
9.09	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
8.82	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
8.82	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
8.57	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
8.57	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
8.57	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
8.57	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
8.33	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
8.33	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
7.69	Single	8HS2	Fab046	8HS2-GPR20-Fab046
7.41	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
7.41	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
7.14	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
7.14	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
6.90	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
6.90	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
6.67	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
6.67	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
6.67	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
6.45	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.45	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
6.38	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
6.06	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.88	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
4.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
4.00	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
4.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
4.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
4.00	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
4.00	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
4.00	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.00	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
4.00	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
4.00	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.00	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.00	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
4.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
4.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
4.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
4.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
4.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
4.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
4.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
4.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
4.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
4.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
4.00	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
4.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
4.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
4.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
4.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
4.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
4.00	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Single	7FII	hCG	7FII-LH-hCG-6fuf
4.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
4.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
4.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
4.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
4.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
4.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
4.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
4.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
4.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.00	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
4.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
4.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
4.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
4.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
4.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
4.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
4.00	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
4.00	Single	7XW7	K1-70	7XW7-TSH-K1-70
4.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
4.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
4.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
4.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
4.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
4.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
4.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
4.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
4.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
4.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
4.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
4.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
4.00	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
4.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
4.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
4.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
4.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
4.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
4.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
4.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
4.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
4.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
4.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
4.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.00	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.00	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
4.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
4.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
4.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
4.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
4.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
4.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.00	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
4.00	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
4.00	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
4.00	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
4.00	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
4.00	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
4.00	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.00	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.00	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
4.00	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
4.00	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.00	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.00	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.00	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
4.00	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.00	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
4.00	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.00	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
4.00	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
4.00	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.00	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.00	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
4.00	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
4.00	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.00	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.00	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
4.00	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
4.00	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
4.00	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
4.00	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
4.00	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
4.00	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
4.00	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
4.00	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
3.85	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
3.85	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
3.85	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
3.85	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
3.85	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
3.85	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
3.85	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
3.85	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
3.85	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
3.85	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
3.70	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
3.70	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
3.57	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
3.57	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
3.57	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
3.57	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
3.57	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
3.57	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
3.57	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
3.45	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
3.45	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
3.45	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
3.33	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
3.23	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
3.23	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
2.94	Single	8IYX	YL-365	8IYX-GPR34-YL-365
2.63	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
2.56	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
2.38	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7

Consensus Members
	Id	Members
	gi_opioid	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
	gi_endothelin	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
	gi_formylpeptide	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
	gi_galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
	gi_ghrelin	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
	gi_neuromedin	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
	gi_neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
	gi_relaxin	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
	gi_neuropeptide	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
	gi_somatostatin	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
	gi_apelin	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
	gi_compl-peptide	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
	gi_cck	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2

Net Summary
I_min	2.732
Number of Linked Nodes	971
Number of Links	1158
Number of Hubs	180
Number of Links mediated by Hubs	713
Number of Communities	20
Number of Nodes involved in Communities	233
Number of Links involved in Communities	337

Path Summary
Number Of Nodes in MetaPath	87
Number Of Links MetaPath	86
Number of Shortest Paths	4292364
Length Of Smallest Path	3
Average Path Length	40.415
Length of Longest Path	61
Minimum Path Strength	0.0784341
Average Path Strength	4.81805
Maximum Path Strength	21.6682
Minimum Path Correlation	0.700787
Average Path Correlation	0.980983
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.75439
Average % Of Corr. Nodes	27.1926
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	50.9915
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gi_class-a	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar

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