psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.11	G.HN.33	3.22125	Yes	No	0	2	4
2	G.HN.11	G.HN.34	2.99625	Yes	No	0	2	3
3	G.HN.30	G.HN.33	6.2575	No	No	0	7	4
4	G.HN.37	G.HN.41	3.0375	No	No	0	3	4
5	G.HN.37	b.b5x2	3.88125	No	Yes	0	3	7
6	G.HN.39	G.HN.43	2.43	No	Yes	0	5	9
7	G.HN.39	b.b5x5	2.68313	No	Yes	0	5	5
8	G.HN.40	b.b5x2	6.79812	No	Yes	0	7	7
9	G.HN.40	b.b5x3	3.63375	No	Yes	0	7	9
10	G.HN.43	G.HN.47	2.22687	Yes	No	3	9	6
11	G.HN.43	b.b5x3	4.99688	Yes	Yes	3	9	9
12	G.HN.44	G.HN.48	2.53	No	No	0	6	3
13	G.HN.44	b.b5x3	11.75	No	Yes	0	6	9
14	G.HN.47	b.b4x2	3.70125	No	Yes	0	6	8
15	G.HN.47	b.b5x3	2.55562	No	Yes	3	6	9
16	G.HN.50	b.b4x2	5.87687	No	Yes	0	5	8
17	G.S1.01	G.S3.02	8.3875	No	No	0	6	4
18	G.S1.01	G.S3.04	11.475	No	Yes	0	6	6
19	G.S1.02	G.S1.04	3.07312	Yes	Yes	4	5	7
20	G.S1.02	G.S3.01	4.37687	Yes	Yes	4	5	4
21	G.S1.02	G.S3.03	7.95	Yes	Yes	4	5	7
22	G.S1.02	G.h2s4.05	5.15688	Yes	No	0	5	7
23	G.H5.11	G.S1.02	4.41062	No	Yes	4	8	5
24	G.S1.03	G.S3.04	2.24625	No	Yes	1	9	6
25	G.S1.03	G.S3.06	7.83	No	Yes	1	9	5
26	G.S1.04	G.S3.03	3.88	Yes	Yes	4	7	7
27	G.S1.04	G.S3.05	2.475	Yes	Yes	0	7	7
28	G.S1.04	G.S4.03	5.44125	Yes	Yes	4	7	7
29	G.S1.05	G.h2s4.01	9.44125	Yes	Yes	1	9	9
30	G.S1.05	G.h2s4.04	2.42125	Yes	No	0	9	9
31	G.S1.05	G.S4.02	2.67562	Yes	Yes	1	9	8
32	G.H1.01	G.S1.06	4.5825	Yes	Yes	4	9	8
33	G.S1.06	G.S3.05	4.15312	Yes	Yes	0	8	7
34	G.S1.06	G.S3.07	4.74938	Yes	Yes	4	8	9
35	G.S1.06	G.S4.03	3.02938	Yes	Yes	4	8	7
36	G.S1.07	G.S4.02	2.58437	Yes	Yes	1	9	8
37	G.S1.07	G.S4.04	3.27625	Yes	Yes	1	9	9
38	G.H3.12	G.S1.07	5.08313	No	Yes	1	8	9
39	G.H1.01	G.s1h1.01	3.7025	Yes	No	0	9	9
40	G.H3.01	G.s1h1.04	4.07062	No	No	0	9	9
41	G.H1.01	G.s1h1.05	2.77313	Yes	No	0	9	9
42	G.H1.03	G.s1h1.06	2.9575	No	No	0	9	9
43	G.H1.01	G.S3.07	6.74062	Yes	Yes	4	9	9
44	G.H1.01	G.S4.05	3.02938	Yes	Yes	4	9	7
45	G.H1.04	G.S4.05	2.75938	Yes	Yes	4	7	7
46	G.H1.04	G.S5.05	5.34	Yes	Yes	4	7	9
47	G.H1.04	G.S5.07	3.62625	Yes	No	4	7	9
48	G.H1.04	G.s6h5.01	3.04	Yes	Yes	4	7	9
49	G.H1.07	G.H5.03	8.08562	No	Yes	0	9	8
50	G.H1.08	G.S2.06	7.30625	No	No	0	8	9
51	G.H1.08	G.H5.04	2.47062	No	No	0	8	7
52	G.H1.08	G.H5.07	2.755	No	No	0	8	8
53	G.hfs2.07	b.l7x4	4.45375	No	Yes	0	9	9
54	G.S2.01	G.S3.06	3.21938	No	Yes	1	9	5
55	G.S2.01	b.l5x5	7.3425	No	Yes	1	9	9
56	G.S2.01	b.l7x2	3.30125	No	Yes	1	9	9
57	G.S2.03	G.S2.05	4.615	No	Yes	0	9	3
58	G.S2.03	G.S3.06	6.41375	No	Yes	1	9	5
59	G.S2.03	b.l5x5	2.79313	No	Yes	1	9	9
60	G.S2.05	G.S3.02	3.43312	Yes	No	0	3	4
61	G.S2.05	G.S3.04	10.8075	Yes	Yes	0	3	6
62	G.S2.06	G.S3.03	14.7338	No	Yes	0	9	7
63	G.S2.07	G.S3.02	6.16313	No	No	0	3	4
64	G.S2.08	G.s2s3.01	10.7819	Yes	No	4	5	4
65	G.H5.04	G.S2.08	9.42438	No	Yes	0	7	5
66	G.H5.05	G.S2.08	3.72937	No	Yes	4	5	5
67	G.H5.08	G.S2.08	5.62813	Yes	Yes	4	8	5
68	G.H5.05	G.s2s3.01	4.745	No	No	4	5	4
69	G.H5.08	G.s2s3.01	6.43563	Yes	No	4	8	4
70	G.S3.01	G.S3.03	8.1475	Yes	Yes	4	4	7
71	G.H5.08	G.S3.01	4.64188	Yes	Yes	4	8	4
72	G.S3.01	I2x51	3.16375	Yes	No	4	4	6
73	G.H5.08	G.S3.03	2.3425	Yes	Yes	4	8	7
74	G.H5.11	G.S3.03	5.24	No	Yes	4	8	7
75	G.S3.04	G.S3.06	4.72937	Yes	Yes	1	6	5
76	G.S3.06	G.h2s4.01	4.08813	Yes	Yes	1	5	9
77	G.S3.06	b.l5x5	14.6581	Yes	Yes	1	5	9
78	G.S3.07	G.s3h2.01	3.21437	Yes	No	0	9	9
79	G.H2.07	G.S3.08	7.96875	Yes	No	0	9	9
80	G.H2.02	G.s3h2.03	3.42812	Yes	Yes	1	8	9
81	G.H2.07	G.s3h2.03	6.5025	Yes	Yes	1	9	9
82	G.s3h2.03	b.l7x2	4.32312	Yes	Yes	1	9	9
83	G.s3h2.03	b.l7x4	4.0425	Yes	Yes	0	9	9
84	G.s3h2.03	b.l9x6	4.57812	Yes	Yes	1	9	8
85	G.H2.02	G.H2.07	2.31625	Yes	Yes	1	8	9
86	G.H2.02	b.l9x6	4.77125	Yes	Yes	1	8	8
87	G.H2.02	b.l13x6	3.1275	Yes	Yes	1	8	9
88	G.H2.03	G.H2.05	7.425	Yes	No	1	9	8
89	G.H2.03	G.H2.06	2.61563	Yes	Yes	1	9	9
90	G.H2.03	b.l13x6	4.63	Yes	Yes	1	9	9
91	G.H2.03	b.l15x1	2.66	Yes	Yes	1	9	7
92	G.H2.04	G.H2.07	3.875	Yes	Yes	1	9	9
93	G.H2.04	G.H2.08	2.74125	Yes	Yes	1	9	8
94	G.H2.04	G.H3.08	3.64125	Yes	No	1	9	9
95	G.H2.04	G.H3.11	5.27125	Yes	No	0	9	7
96	G.H2.04	G.H3.12	4.38375	Yes	No	1	9	8
97	G.H2.06	b.l9x6	3.20687	Yes	Yes	1	9	8
98	G.H2.06	b.b14x1	6.48	Yes	No	1	9	8
99	G.H2.06	b.l15x1	5.25562	Yes	Yes	1	9	7
100	G.H2.06	b.l17x6	8.12625	Yes	Yes	1	9	9
101	G.H2.06	b.b18x1	4.46187	Yes	No	1	9	9
102	G.H2.06	b.l19x1	3.37188	Yes	Yes	1	9	9
103	G.H2.07	G.H2.08	2.2725	Yes	Yes	1	9	8
104	G.H2.07	G.h2s4.01	4.135	Yes	Yes	1	9	9
105	G.H2.07	b.l7x2	2.7075	Yes	Yes	1	9	9
106	G.H2.07	b.l9x6	2.47187	Yes	Yes	1	9	8
107	G.H2.08	G.H3.15	2.83437	Yes	No	1	8	8
108	G.H2.08	G.H3.17	2.20312	Yes	Yes	1	8	5
109	G.H2.08	G.H3.18	5.17813	Yes	Yes	1	8	9
110	G.H2.09	G.H2.10	2.6725	Yes	No	1	8	7
111	G.H2.09	G.H3.17	9.06125	Yes	Yes	1	8	5
112	G.H2.09	b.b2x1	6.3275	Yes	Yes	1	8	8
113	G.H2.09	b.l28x1	6.87812	Yes	Yes	1	8	9
114	G.H2.10	b.b2x1	5.04313	No	Yes	1	7	8
115	G.H2.10	b.l3x1	4.29313	No	No	1	7	9
116	G.h2s4.01	b.l5x5	10.2125	Yes	Yes	1	9	9
117	G.h2s4.01	b.l7x2	2.44	Yes	Yes	1	9	9
118	G.H3.17	G.h2s4.02	7.76625	Yes	No	0	5	7
119	G.h2s4.02	b.l1x6	6.24375	No	No	0	7	9
120	G.S4.01	G.S5.03	2.23125	No	Yes	0	8	8
121	G.H3.18	G.S4.02	7.85125	Yes	Yes	1	9	8
122	G.S4.02	G.h3s5.03	3.23	Yes	No	1	8	7
123	G.S4.02	G.S5.02	2.85	Yes	Yes	1	8	6
124	G.S4.03	G.S5.03	2.57375	Yes	Yes	4	7	8
125	G.S4.03	G.S5.05	3.21688	Yes	Yes	4	7	9
126	G.S4.04	G.S4.06	2.78375	Yes	Yes	0	9	7
127	G.H3.08	G.S4.04	5.93813	No	Yes	1	9	9
128	G.H3.09	G.S4.04	12.8594	Yes	Yes	1	9	9
129	G.S4.04	G.S5.04	3.57437	Yes	Yes	1	9	9
130	G.S4.05	G.S5.05	2.44313	Yes	Yes	4	7	9
131	G.S4.05	G.S5.07	2.85125	Yes	No	4	7	9
132	G.H3.05	G.S4.06	2.72938	No	Yes	0	9	7
133	G.H4.15	G.S4.06	6.225	Yes	Yes	0	8	7
134	G.S4.07	G.s4h3.03	4.7275	No	No	0	8	8
135	G.S5.06	G.s4h3.01	7.78313	Yes	Yes	1	8	7
136	G.HG.04	G.s4h3.01	8.7525	Yes	Yes	1	9	7
137	G.H4.11	G.s4h3.01	3.11937	No	Yes	0	7	7
138	G.S6.05	G.s4h3.01	2.28688	Yes	Yes	1	4	7
139	G.s4h3.02	G.s5hg.01	5.7375	No	No	1	9	9
140	G.HG.03	G.s4h3.02	5.06563	Yes	No	1	6	9
141	G.HG.07	G.s4h3.02	3.34688	Yes	No	1	9	9
142	G.H3.01	G.s4h3.03	11.6106	No	No	0	9	8
143	G.s4h3.04	G.s4h3.05	18.3194	Yes	No	1	8	9
144	G.H3.02	G.s4h3.04	2.3925	No	Yes	0	8	8
145	G.HG.04	G.s4h3.04	4.9025	Yes	Yes	1	9	8
146	G.HG.07	G.s4h3.04	4.47688	Yes	Yes	1	9	8
147	G.HG.08	G.s4h3.04	3.25063	No	Yes	1	6	8
148	G.HG.13	G.s4h3.04	2.5425	No	Yes	1	7	8
149	G.HG.15	G.s4h3.04	4.1025	Yes	Yes	0	7	8
150	G.hgh4.01	G.s4h3.04	4.5375	No	Yes	0	6	8
151	G.HG.07	G.s4h3.05	6.91438	Yes	No	1	9	9
152	G.HG.13	G.s4h3.05	4.50813	No	No	1	7	9
153	G.H3.01	G.s4h3.06	4.55563	No	No	0	9	8
154	G.H3.03	G.s4h3.15	3.19	No	No	0	4	9
155	G.H3.02	G.hgh4.02	3.06625	No	Yes	0	8	7
156	G.H3.06	G.hgh4.02	4.04	No	Yes	0	6	7
157	G.H3.06	G.H4.15	3.34375	No	Yes	0	6	8
158	G.H3.06	G.h4s6.01	3.09312	No	Yes	0	6	4
159	G.H3.08	G.H3.12	2.23125	No	No	1	9	8
160	G.H3.09	G.H3.13	3.40625	Yes	Yes	1	9	5
161	G.H3.09	G.S5.02	3.77	Yes	Yes	1	9	6
162	G.H3.09	G.S5.04	2.74188	Yes	Yes	1	9	9
163	G.H3.09	G.H4.15	4.8225	Yes	Yes	1	9	8
164	G.H3.09	G.h4s6.01	4.7175	Yes	Yes	0	9	4
165	G.H3.09	G.S6.01	2.74625	Yes	No	0	9	5
166	G.H3.10	G.H3.14	7.40625	No	No	0	5	8
167	G.H3.10	G.h4s6.01	2.20438	No	Yes	0	5	4
168	G.H3.13	G.S5.02	2.76	Yes	Yes	1	5	6
169	G.H3.13	G.h4s6.02	2.35875	Yes	Yes	1	5	8
170	G.H3.13	G.h4s6.11	5.55937	Yes	Yes	1	5	7
171	G.H3.14	G.h4s6.03	9.52687	No	No	0	8	5
172	G.H3.14	G.h4s6.04	2.715	No	Yes	0	8	4
173	G.H3.15	G.H3.17	4.44938	No	Yes	1	8	5
174	G.H3.15	G.H3.18	3.77312	No	Yes	1	8	9
175	G.H3.16	G.H3.17	12.5431	No	Yes	0	4	5
176	G.H3.17	b.l25x6	3.4375	Yes	Yes	1	5	8
177	G.H3.18	G.h3s5.03	5.35063	Yes	No	1	9	7
178	G.h3s5.01	G.h4s6.04	3.47813	No	Yes	0	3	4
179	G.h3s5.02	G.h4s6.10	2.34875	No	No	0	4	3
180	G.S5.01	G.S6.02	3.8975	No	Yes	0	7	7
181	G.H5.14	G.S5.01	4.13875	No	No	0	7	7
182	G.S5.02	G.h4s6.11	4.54313	Yes	Yes	1	6	7
183	G.S5.03	G.S5.05	2.9825	Yes	Yes	4	8	9
184	G.H5.06	G.S5.03	2.51062	No	Yes	0	3	8
185	G.H5.10	G.S5.03	3.655	No	Yes	0	6	8
186	G.S5.04	G.S5.06	4.32687	Yes	Yes	1	9	8
187	G.H4.15	G.S5.04	4.41188	Yes	Yes	1	8	9
188	G.S5.04	G.S6.03	6.44875	Yes	Yes	1	9	5
189	G.S5.05	G.S6.04	5.37437	Yes	No	4	9	9
190	G.S5.05	G.s6h5.01	6.08187	Yes	Yes	4	9	9
191	G.H5.03	G.S5.05	4.45312	Yes	Yes	4	8	9
192	G.H5.07	G.S5.05	2.45625	No	Yes	0	8	9
193	G.S5.06	G.S6.03	2.39625	Yes	Yes	1	8	5
194	G.S5.06	G.S6.05	7.91813	Yes	Yes	1	8	4
195	G.S5.07	G.s6h5.01	5.66562	No	Yes	4	9	9
196	G.H4.03	G.HG.01	6.56812	Yes	No	0	4	5
197	G.HG.01	G.s6h5.02	3.13312	No	No	0	5	7
198	G.HG.02	G.HG.03	4.57938	No	Yes	0	9	6
199	G.HG.04	G.HG.08	4.23875	Yes	No	1	9	6
200	G.H4.03	G.HG.04	3.74188	Yes	Yes	0	4	9
201	G.H4.06	G.HG.04	2.59688	No	Yes	0	7	9
202	G.H4.03	G.HG.05	14.7306	Yes	No	0	4	5
203	G.H4.01	G.HG.08	2.47937	No	No	0	3	6
204	G.HG.13	G.HG.14	3.44875	No	No	0	7	5
205	G.HG.14	G.HG.16	2.515	No	No	0	5	4
206	G.HG.15	G.hgh4.02	5.42125	Yes	Yes	0	7	7
207	G.HG.15	G.hgh4.05	6.08063	Yes	Yes	0	7	7
208	G.H4.11	G.HG.15	2.67313	No	Yes	0	7	7
209	G.hgh4.01	G.hgh4.02	7.72625	No	Yes	0	6	7
210	G.hgh4.02	G.hgh4.04	5.68125	Yes	No	7	7	6
211	G.H4.10	G.hgh4.02	5.21125	Yes	Yes	7	6	7
212	G.H4.14	G.hgh4.02	11.5562	No	Yes	7	5	7
213	G.hgh4.03	G.hgh4.04	2.8475	No	No	0	5	6
214	G.H4.10	G.hgh4.04	4.34937	Yes	No	7	6	6
215	G.hgh4.05	G.hgh4.07	5.34312	Yes	No	7	7	7
216	G.H4.05	G.hgh4.05	3.43625	Yes	Yes	7	4	7
217	G.H4.10	G.hgh4.05	14.585	Yes	Yes	7	6	7
218	G.H4.05	G.hgh4.07	2.24937	Yes	No	7	4	7
219	G.H4.02	G.hgh4.08	4.89937	No	No	7	5	3
220	G.H4.05	G.hgh4.08	5.9275	Yes	No	7	4	3
221	G.H4.02	G.H4.04	2.46938	No	No	0	5	4
222	G.H4.02	G.H4.05	3.175	No	Yes	7	5	4
223	G.H4.03	G.H4.04	3.64625	Yes	No	0	4	4
224	G.H4.03	G.H4.07	3.33375	Yes	No	0	4	5
225	G.H4.07	G.S6.05	3.03062	No	Yes	0	5	4
226	G.H4.10	G.H4.14	16.4856	Yes	No	7	6	5
227	G.H4.11	G.H4.15	2.58875	No	Yes	0	7	8
228	G.H4.12	G.H4.16	4.6975	No	No	1	5	3
229	G.H4.12	G.S6.03	15.1488	No	Yes	1	5	5
230	G.H4.12	G.S6.05	4.75562	No	Yes	1	5	4
231	G.H4.16	G.S6.01	3.41625	No	No	0	3	5
232	G.H4.16	G.S6.03	4.67188	No	Yes	1	3	5
233	G.h4s6.02	G.h4s6.08	6.205	Yes	No	0	8	3
234	G.h4s6.02	G.h4s6.11	2.53625	Yes	Yes	1	8	7
235	G.S6.01	G.h4s6.02	6.90313	No	Yes	0	5	8
236	G.h4s6.04	G.h4s6.10	3.3975	Yes	No	0	4	3
237	G.h4s6.04	G.h4s6.11	2.555	Yes	Yes	0	4	7
238	G.S6.02	G.h4s6.12	11.8538	Yes	No	0	7	4
239	G.H5.17	G.h4s6.12	2.44688	No	No	10	5	4
240	G.H5.10	G.S6.02	6.25375	No	Yes	0	6	7
241	G.H5.13	G.S6.02	5.82	No	Yes	0	8	7
242	G.H5.03	G.S6.04	3.74563	Yes	No	4	8	9
243	G.H5.06	G.S6.04	21.07	No	No	0	3	9
244	G.H5.03	G.s6h5.01	9.87125	Yes	Yes	4	8	9
245	G.H5.05	G.H5.09	9.22	No	No	0	5	4
246	G.H5.08	G.H5.12	6.64625	Yes	No	0	8	6
247	G.H5.08	I2x51	2.7125	Yes	No	4	8	6
248	G.H5.13	I3	3.26313	No	Yes	0	8	4
249	G.H5.14	G.H5.18	3.41625	No	No	0	7	4
250	G.H5.15	G.H5.19	3.63	No	No	0	7	8
251	G.H5.15	I2x54	3.64062	No	No	0	7	5
252	G.H5.16	I2x50	4.2975	No	No	0	6	8
253	3x53	G.H5.19	4.2875	No	No	0	8	8
254	G.H5.20	G.H5.25	3.11438	Yes	Yes	0	9	7
255	G.H5.20	G.H5.26	12.5588	Yes	Yes	0	9	5
256	3x54	G.H5.20	3.2075	No	Yes	0	9	9
257	2x37	G.H5.22	2.49437	No	No	0	7	4
258	G.H5.23	G.H5.25	3.075	No	Yes	2	4	7
259	3x50	G.H5.23	5.83	Yes	No	2	9	4
260	3x50	G.H5.25	7.43812	Yes	Yes	2	9	7
261	6x37	G.H5.25	3.66375	No	Yes	0	7	7
262	6x29	G.H5.26	4.52812	No	Yes	0	4	5
263	6x33	G.H5.26	4.5625	No	Yes	10	7	5
264	b.1x11	g.h1x11	4.58687	Yes	No	0	6	9
265	b.lh12x2	g.l1x6	8.6425	Yes	No	0	8	4
266	b.lh12x2	g.h2x2	6.80687	Yes	No	0	8	9
267	b.h2x3	b.lh12x4	8.06063	No	No	0	1	3
268	b.h2x1	b.h2x5	3.41	Yes	No	0	5	5
269	b.b21x4	b.h2x1	3.28625	No	Yes	0	5	5
270	b.b21x5	b.h2x1	5.12313	Yes	Yes	0	4	5
271	b.h2x1	g.h2x5	3.35063	Yes	No	0	5	6
272	b.b21x5	b.h2x2	2.29813	Yes	No	0	4	1
273	b.h2x5	b.l24x2	4.97688	No	Yes	0	5	6
274	b.h2x5	g.h2x9	2.3525	No	No	0	5	4
275	b.l22x5	b.lhb1x3	5.635	Yes	Yes	0	9	2
276	b.l24x3	b.lhb1x5	3.4525	Yes	No	0	5	1
277	b.lhb1x6	b.lhb1x9	2.6875	Yes	Yes	0	3	3
278	b.l22x5	b.lhb1x6	6.3775	Yes	Yes	11	9	3
279	b.b24x7	b.lhb1x6	7.1175	No	Yes	11	9	3
280	b.lhb1x6	g.ctx6	3.16625	Yes	Yes	11	3	6
281	b.lhb1x10	b.lhb1x8	2.70312	No	No	0	4	2
282	b.lhb1x11	b.lhb1x9	2.37125	No	Yes	0	4	3
283	b.b23x1	b.lhb1x9	2.76312	Yes	Yes	0	5	3
284	b.b1x1	b.lhb1x10	3.1375	No	No	0	5	4
285	b.b25x7	b.lhb1x11	4.50375	No	No	0	7	4
286	b.lhb1x11	g.ctx5	3.62125	No	No	0	4	9
287	b.b1x1	b.b1x3	4.13	No	No	0	5	7
288	b.b1x2	b.b28x4	6.28563	No	Yes	9	3	6
289	b.b1x2	b.b28x6	9.70187	No	Yes	9	3	9
290	b.b1x3	b.b28x7	7.23125	No	No	3	7	9
291	b.b1x3	g.ctx16	3.14125	No	Yes	3	7	8
292	b.b1x4	b.b5x1	4.7675	Yes	No	0	7	5
293	b.b1x4	b.b28x5	4.77625	Yes	No	3	7	5
294	b.b1x4	g.ctx16	4.61188	Yes	Yes	3	7	8
295	b.b1x5	b.l1x1	8.56875	No	No	0	3	7
296	b.b1x5	b.b28x4	6.29063	No	Yes	0	3	6
297	b.b1x6	b.b3x2	2.24875	Yes	Yes	3	9	5
298	b.b1x6	b.b4x6	17.01	Yes	Yes	3	9	9
299	b.b1x6	b.b5x1	3.1325	Yes	No	0	9	5
300	b.b1x6	b.b28x3	5.01625	Yes	Yes	3	9	7
301	b.b1x6	b.b28x5	3.29812	Yes	No	3	9	5
302	b.b28x2	b.l1x1	6.41187	No	No	0	4	7
303	b.b5x3	b.l1x2	3.1625	Yes	No	0	9	9
304	b.l1x3	b.l1x7	9.03	Yes	No	0	9	9
305	b.b3x4	b.l1x3	7.32312	No	Yes	3	9	9
306	b.b3x6	b.l1x3	12.99	No	Yes	3	9	9
307	b.l1x3	b.l3x2	3.465	Yes	Yes	3	9	9
308	b.b4x4	b.l1x3	12.7619	No	Yes	3	8	9
309	b.b4x6	b.l1x3	4.16437	Yes	Yes	3	9	9
310	b.l1x5	b.l3x2	3.85875	No	Yes	0	7	9
311	b.b2x1	b.l1x6	6.86687	Yes	No	1	8	9
312	b.l1x6	b.l28x1	22.6294	No	Yes	1	9	9
313	b.b28x3	b.l1x7	3.12	Yes	No	0	7	9
314	b.b2x1	b.l3x1	13.3869	Yes	No	1	8	9
315	b.b2x1	b.l28x1	7.89687	Yes	Yes	1	8	9
316	b.b2x3	b.b2x5	4.5075	Yes	Yes	3	6	7
317	b.b2x3	b.b3x2	3.35812	Yes	Yes	3	6	5
318	b.b26x2	b.b2x3	5.56875	No	Yes	0	7	6
319	b.b27x2	b.b2x3	2.91812	No	Yes	3	5	6
320	b.b28x3	b.b2x3	2.73812	Yes	Yes	3	7	6
321	b.b2x4	b.b6x5	3.40625	No	Yes	0	6	6
322	b.b10x4	b.b2x4	13.2556	No	No	0	6	6
323	b.b2x5	b.b3x2	9.25187	Yes	Yes	3	7	5
324	b.b2x5	b.l4x1	5.01813	Yes	No	3	7	5
325	b.b26x4	b.b2x5	2.81	No	Yes	0	5	7
326	b.b2x5	b.l27x1	11.2175	Yes	No	3	7	7
327	b.b27x2	b.b2x5	4.0525	No	Yes	3	5	7
328	b.b6x5	b.l2x1	3.71375	Yes	No	0	6	5
329	b.l2x3	b.l2x5	3.05063	No	No	0	8	5
330	b.b3x1	b.l2x3	4.74938	No	No	0	5	8
331	b.l27x1	b.l2x4	6.4975	No	No	3	7	5
332	b.l27x3	b.l2x4	9.2925	No	No	3	7	5
333	b.b4x7	b.l2x5	14.2906	No	No	0	8	5
334	b.l2x5	b.l4x2	23.0187	No	Yes	0	5	4
335	b.b3x1	b.b4x7	2.62687	No	No	0	5	8
336	b.b3x1	b.b6x5	3.07438	No	Yes	0	5	6
337	b.b3x2	b.b4x6	6.40625	Yes	Yes	3	5	9
338	b.b3x3	b.b4x3	2.6075	Yes	Yes	0	8	7
339	b.b3x3	b.b4x5	3.07062	Yes	Yes	0	8	7
340	b.b3x3	b.b6x3	2.99062	Yes	No	0	8	8
341	b.b3x3	b.b6x5	5.59938	Yes	Yes	0	8	6
342	b.b3x4	b.b4x6	6.63937	No	Yes	3	9	9
343	b.b28x3	b.b3x4	4.69063	Yes	No	3	7	9
344	b.b3x5	b.b4x3	2.56063	No	Yes	0	9	7
345	b.b3x5	b.l5x6	3.39188	No	No	0	9	9
346	b.b3x5	b.b6x3	3.4975	No	No	0	9	8
347	b.b3x6	b.l3x2	9.20438	No	Yes	3	9	9
348	b.l3x1	b.l5x5	6.09437	No	Yes	1	9	9
349	b.b4x2	b.l3x2	6.04875	Yes	Yes	0	8	9
350	b.b4x1	b.l5x1	3.95438	No	Yes	0	8	8
351	b.b4x1	b.l5x4	2.78437	No	No	0	8	8
352	b.b4x2	b.b5x8	2.50813	Yes	No	0	8	5
353	b.b4x3	b.b5x7	3.655	Yes	Yes	5	7	7
354	b.b4x3	b.l5x1	4.49813	Yes	Yes	5	7	8
355	b.b4x3	b.b7x4	3.66813	Yes	Yes	5	7	8
356	b.b4x4	b.b4x6	14.6063	No	Yes	3	8	9
357	b.b4x4	b.b5x3	4.36063	No	Yes	3	8	9
358	b.b4x5	b.b5x4	3.74563	Yes	No	5	7	5
359	b.b4x5	b.b5x5	6.71313	Yes	Yes	5	7	5
360	b.b4x5	b.l8x1	3.47625	Yes	Yes	5	7	5
361	b.b4x6	b.b5x3	10.15	Yes	Yes	3	9	9
362	b.b28x3	b.b4x6	2.99188	Yes	Yes	3	7	9
363	b.b4x7	b.l4x3	7.31938	No	No	0	8	6
364	b.l4x1	b.l4x2	2.78	No	Yes	3	5	4
365	b.l4x1	g.ctx16	4.04313	No	Yes	3	5	8
366	b.l4x2	g.ctx15	10.0869	Yes	Yes	3	4	9
367	b.l4x2	g.ctx16	5.60938	Yes	Yes	3	4	8
368	b.b5x2	b.l4x3	8.86375	Yes	No	0	7	6
369	b.b5x4	b.b5x5	5.79875	No	Yes	5	5	5
370	b.b5x5	b.l8x8	4.84313	Yes	Yes	5	5	4
371	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
372	b.b5x7	b.b8x4	5.97	Yes	Yes	5	7	6
373	b.b5x7	b.l8x8	6.24063	Yes	Yes	5	7	4
374	b.l5x1	b.l5x6	4.19062	Yes	No	5	8	9
375	b.b7x4	b.l5x1	2.58	Yes	Yes	5	8	8
376	b.b8x4	b.l5x1	4.83625	Yes	Yes	5	6	8
377	b.l5x2	b.l8x10	4.08563	No	No	5	6	4
378	b.b9x3	b.l5x2	9.45125	Yes	No	5	6	6
379	b.l5x3	b.l5x5	2.7825	No	Yes	0	8	9
380	b.l5x3	b.l7x3	8.83063	No	No	0	8	9
381	b.l5x4	b.l5x5	2.23875	No	Yes	0	8	9
382	b.l5x5	b.l7x2	4.63	Yes	Yes	1	9	9
383	b.b7x4	b.l5x6	2.35063	Yes	No	5	8	9
384	b.b6x1	b.l7x1	2.50938	No	No	0	9	9
385	b.b6x1	b.l7x2	2.20687	No	Yes	1	9	9
386	b.b6x1	b.l9x6	4.18937	No	Yes	1	9	8
387	b.b10x3	b.b6x2	4.96438	No	No	0	8	8
388	b.b6x5	b.l6x4	4.25562	Yes	No	0	6	5
389	b.b6x5	b.b7x2	2.83812	Yes	No	5	6	8
390	b.b6x5	b.l8x1	3.29813	Yes	Yes	5	6	5
391	b.b10x5	b.l6x1	6.06812	Yes	No	0	9	6
392	b.b10x5	b.l6x2	3.60813	Yes	No	0	9	6
393	b.l6x3	b.l6x5	6.98438	No	Yes	12	6	4
394	b.l10x3	b.l6x3	9.015	No	No	12	6	6
395	b.b7x1	b.l6x5	3.92438	Yes	Yes	12	4	4
396	b.l6x5	b.l8x2	9.09188	Yes	No	0	4	4
397	b.l10x3	b.l6x5	5.30125	No	Yes	12	6	4
398	b.b7x1	b.b8x3	3.4025	Yes	Yes	0	4	6
399	b.b7x1	b.b8x5	9.96	Yes	No	0	4	4
400	b.b7x1	b.b9x1	3.17813	Yes	No	0	4	4
401	b.b7x1	b.l10x3	8.12187	Yes	No	12	4	6
402	b.b7x2	b.b8x4	3.15812	No	Yes	5	8	6
403	b.b7x2	b.l8x1	4.00437	No	Yes	5	8	5
404	b.b10x5	b.b7x3	3.20438	Yes	No	0	9	9
405	b.b7x4	b.b8x4	4.53813	Yes	Yes	5	8	6
406	b.b7x5	b.l9x7	2.77875	No	No	0	9	7
407	b.l7x2	b.l9x6	2.855	Yes	Yes	1	9	8
408	b.l7x3	b.l7x5	4.9875	No	Yes	0	9	6
409	b.l7x4	b.l9x5	3.71188	Yes	No	0	9	8
410	b.b9x3	b.l7x5	4.27063	Yes	Yes	0	6	6
411	b.b8x1	b.b9x4	3.37125	No	Yes	0	8	9
412	b.b10x3	b.b8x1	2.38875	No	No	1	8	8
413	b.b11x4	b.b8x1	2.32375	Yes	No	1	9	8
414	b.b8x2	b.b8x4	6.75688	No	Yes	5	8	6
415	b.b8x2	b.b9x3	4.58187	No	Yes	5	8	6
416	b.b10x5	b.b8x3	3.84688	Yes	Yes	0	9	6
417	b.b8x3	b.l12x1	4.05062	Yes	No	0	6	6
418	b.b8x4	b.l8x8	2.20563	Yes	Yes	5	6	4
419	b.b8x4	b.l8x10	6.70375	Yes	No	5	6	4
420	b.b8x5	b.l8x3	3.9275	No	No	0	4	3
421	b.l8x1	b.l8x8	3.53875	Yes	Yes	5	5	4
422	b.l8x3	b.l8x5	2.37937	No	Yes	15	3	3
423	b.l8x3	b.l8x9	3.8	No	No	15	3	3
424	b.l8x4	b.l8x5	2.61562	No	Yes	0	3	3
425	b.l8x5	b.l8x7	5.505	Yes	No	0	3	3
426	b.l8x5	b.l8x9	3.49188	Yes	No	15	3	3
427	b.b9x3	b.l8x10	3.12063	Yes	No	5	6	4
428	b.b9x2	b.b9x4	2.27688	No	Yes	0	5	9
429	b.b12x6	b.b9x4	13.3119	Yes	Yes	0	8	9
430	b.l9x3	b.l9x7	3.85625	Yes	No	1	9	7
431	b.b11x4	b.l9x3	4.88062	Yes	Yes	1	9	9
432	b.b11x6	b.l9x3	16.0413	Yes	Yes	1	9	9
433	b.l11x2	b.l9x3	6.93062	Yes	Yes	1	9	9
434	b.b12x2	b.l9x3	2.91062	Yes	Yes	1	7	9
435	b.b12x4	b.l9x3	3.02125	No	Yes	1	4	9
436	b.b12x6	b.l9x3	6.01813	Yes	Yes	1	8	9
437	b.b13x3	b.l9x3	2.47375	Yes	Yes	1	4	9
438	b.l11x2	b.l9x4	7.3175	Yes	No	0	9	5
439	b.b10x1	b.l9x6	3.34	No	Yes	0	9	8
440	b.l11x1	b.l9x6	6.42688	No	Yes	1	9	8
441	b.l13x6	b.l9x6	7.185	Yes	Yes	1	9	8
442	b.b14x1	b.l9x6	3.44125	No	Yes	1	8	8
443	b.b11x4	b.l9x7	4.7925	Yes	No	1	9	7
444	b.b10x1	b.b11x5	2.75062	No	No	0	9	6
445	b.b10x2	b.b10x4	4.17875	No	No	0	6	6
446	b.b10x2	b.b14x3	3.6675	No	Yes	0	6	5
447	b.b10x3	b.b11x4	2.64063	No	Yes	1	8	9
448	b.b10x4	b.b14x5	3.03562	No	Yes	0	6	5
449	b.b10x5	b.b11x2	7.06375	Yes	No	0	9	7
450	b.b11x1	b.l10x1	6.15438	No	No	0	5	3
451	b.b14x5	b.l10x1	4.58375	Yes	No	0	5	3
452	b.l10x1	b.l14x4	2.76375	No	No	0	3	1
453	b.b12x7	b.l10x4	9.08875	Yes	No	13	9	3
454	b.l10x4	b.l12x1	2.215	No	No	0	3	6
455	b.l10x4	b.l12x2	6.90188	No	No	13	3	6
456	b.b11x1	b.b12x5	3.32625	No	No	0	5	6
457	b.b11x2	b.b12x6	3.15313	No	Yes	0	7	8
458	b.b11x2	b.l12x1	4.50875	No	No	0	7	6
459	b.b11x3	b.b14x3	4.19062	No	Yes	6	5	5
460	b.b11x3	b.b14x5	3.07312	No	Yes	6	5	5
461	b.b11x3	b.b15x1	4.34062	No	Yes	6	5	9
462	b.b11x4	b.b12x6	9.01875	Yes	Yes	1	9	8
463	b.b11x5	b.l13x7	5.35125	No	Yes	0	6	9
464	b.b11x5	b.b14x3	4.69125	No	Yes	0	6	5
465	b.b11x6	b.l11x1	2.43812	Yes	No	1	9	9
466	b.b11x6	b.l11x2	9.57187	Yes	Yes	1	9	9
467	b.l11x1	b.l13x6	3.875	No	Yes	1	9	9
468	b.b12x2	b.l11x2	11.7444	Yes	Yes	1	7	9
469	b.b12x3	b.b13x7	3.84063	Yes	Yes	6	8	7
470	b.b12x3	b.l13x7	2.66937	Yes	Yes	6	8	9
471	b.b12x3	b.b15x1	2.96688	Yes	Yes	6	8	9
472	b.b12x3	b.b15x3	3.44	Yes	Yes	6	8	9
473	b.b12x4	b.b12x6	4.94625	No	Yes	1	4	8
474	b.b12x4	b.b13x3	5.39875	No	Yes	1	4	4
475	b.b12x5	b.b13x5	4.885	No	No	0	6	4
476	b.b12x6	b.b13x3	15.1262	Yes	Yes	1	8	4
477	b.b12x7	b.l12x2	5.0325	Yes	No	13	9	6
478	b.b12x7	b.l12x3	6.8675	Yes	Yes	13	9	5
479	b.b12x7	b.b13x4	2.89375	Yes	No	0	9	4
480	b.b13x2	b.l12x3	4.87063	No	Yes	0	4	5
481	b.b13x3	b.b13x6	4.78062	Yes	No	0	4	4
482	b.b13x4	b.b13x5	3.14	No	No	0	4	4
483	b.b13x5	b.b13x7	6.08125	No	Yes	0	4	7
484	b.b13x7	b.b15x1	9.37562	Yes	Yes	6	7	9
485	b.b13x7	b.b16x6	14.7819	Yes	Yes	6	7	8
486	b.b13x7	b.b17x1	3.29313	Yes	No	0	7	4
487	b.l13x3	b.l13x7	4.92938	Yes	Yes	6	9	9
488	b.b15x3	b.l13x3	5.75375	Yes	Yes	6	9	9
489	b.b15x5	b.l13x3	7.95687	No	Yes	6	8	9
490	b.b16x4	b.l13x3	16.0475	Yes	Yes	6	6	9
491	b.b16x6	b.l13x3	3.77	Yes	Yes	6	8	9
492	b.l13x4	b.l15x2	6.95562	No	Yes	0	3	9
493	b.l13x6	b.l15x1	3.30625	Yes	Yes	1	9	7
494	b.b15x3	b.l13x7	2.72875	Yes	Yes	6	9	9
495	b.b15x5	b.l13x7	2.64937	No	Yes	6	8	9
496	b.b14x1	b.l15x1	3.13875	No	Yes	1	8	7
497	b.b14x2	b.b18x3	5.22312	No	Yes	0	7	8
498	b.b14x3	b.b15x1	5.09875	Yes	Yes	6	5	9
499	b.b14x4	b.b15x2	2.42313	No	Yes	1	8	6
500	b.b14x4	b.b18x5	6.10875	No	Yes	1	8	5
501	b.b14x5	b.b15x1	3.27125	Yes	Yes	6	5	9
502	b.l14x1	b.l14x3	2.89563	No	No	0	4	5
503	b.b18x5	b.l14x1	3.37812	Yes	No	0	5	4
504	b.l14x2	b.l18x4	3.67937	No	No	0	4	7
505	b.l14x3	b.l14x5	4.98688	No	No	0	5	5
506	b.l14x5	b.l16x2	6	No	No	0	5	9
507	b.b16x5	b.l14x6	3.63125	Yes	No	0	5	3
508	b.b16x7	b.l14x6	4.32687	No	No	0	9	3
509	b.b15x1	b.b16x6	12.9006	Yes	Yes	6	9	8
510	b.b15x1	b.l16x1	2.45625	Yes	No	0	9	4
511	b.b15x2	b.b16x5	3.25937	Yes	Yes	0	6	5
512	b.b15x2	b.b18x3	6.14188	Yes	Yes	1	6	8
513	b.b15x2	b.b18x5	7.53562	Yes	Yes	1	6	5
514	b.b15x2	b.b19x2	7.70063	Yes	Yes	1	6	6
515	b.b15x3	b.b16x6	6.56187	Yes	Yes	6	9	8
516	b.b15x4	b.l17x7	3.30875	No	No	0	6	7
517	b.l15x1	b.l17x6	9.62625	Yes	Yes	1	7	9
518	b.b16x2	b.l15x2	6.25813	No	Yes	0	5	9
519	b.b16x2	b.l17x1	2.6	No	No	0	5	2
520	b.b16x3	b.b19x2	2.59688	No	Yes	0	6	6
521	b.b16x4	b.b16x6	7.685	Yes	Yes	6	6	8
522	b.b16x4	b.b17x3	6.46812	Yes	No	6	6	5
523	b.b16x4	b.b17x6	10.9788	Yes	No	0	6	7
524	b.b16x5	b.b17x4	3.10938	Yes	No	0	5	5
525	b.b16x5	b.b17x5	3.9075	Yes	Yes	0	5	7
526	b.b16x5	b.l20x1	5.70813	Yes	No	0	5	6
527	b.b16x6	b.b17x3	5.46625	Yes	No	6	8	5
528	b.b16x7	b.l16x3	10.9606	No	No	0	9	3
529	b.b16x7	b.b17x4	10.1987	No	No	0	9	5
530	b.l16x2	b.l16x3	4.86812	No	No	0	9	3
531	b.b17x2	b.l16x3	2.95875	No	No	0	3	3
532	b.b17x2	b.b17x4	2.4025	No	No	0	3	5
533	b.b17x2	g.h1x13	2.52562	No	No	0	3	1
534	b.b17x5	b.b17x7	8.05375	Yes	Yes	1	7	8
535	b.b17x5	b.b21x1	10.6856	Yes	Yes	1	7	7
536	b.b17x6	g.h1x14	5.20187	No	No	0	7	9
537	b.b17x7	b.b19x2	11.5875	Yes	Yes	1	8	6
538	b.b17x7	b.b20x6	9.91438	Yes	Yes	1	8	6
539	b.b17x7	b.b21x1	4.85312	Yes	Yes	1	8	7
540	b.l17x3	b.l17x7	6.54438	Yes	No	1	9	7
541	b.b19x4	b.l17x3	7.86937	Yes	Yes	1	8	9
542	b.b19x6	b.l17x3	13.7744	No	Yes	1	9	9
543	b.l17x3	b.l19x2	3.465	Yes	Yes	1	9	9
544	b.b20x2	b.l17x3	3.33938	Yes	Yes	1	6	9
545	b.b20x4	b.l17x3	18.3344	Yes	Yes	1	8	9
546	b.l17x4	b.l19x2	6.09187	No	Yes	0	3	9
547	b.l17x5	b.l17x6	4.51	No	Yes	1	6	9
548	b.l17x5	b.l19x1	4.87625	No	Yes	1	6	9
549	b.l17x5	b.l19x2	2.85188	No	Yes	1	6	9
550	b.l17x6	b.l19x1	6.4025	Yes	Yes	1	9	9
551	b.b19x4	b.l17x7	3.325	Yes	No	1	8	7
552	b.b18x1	b.l19x1	11.1894	No	Yes	1	9	9
553	b.b18x2	b.b22x3	3.39062	No	No	0	5	6
554	b.b18x3	b.b19x2	5.17813	Yes	Yes	1	8	6
555	b.b18x3	b.b19x4	3.705	Yes	Yes	1	8	8
556	b.b18x5	b.l18x4	2.25875	Yes	No	0	5	7
557	b.l18x1	b.l18x2	13.1838	Yes	Yes	8	6	7
558	b.l18x1	b.l18x3	6.79688	Yes	Yes	8	6	5
559	b.b19x1	b.l18x1	2.77125	No	Yes	8	6	6
560	b.b22x5	b.l18x1	9.17875	Yes	Yes	8	7	6
561	b.l18x1	b.l22x4	4.42438	Yes	No	8	6	9
562	b.l18x1	g.h2x8	6.39188	Yes	No	8	6	7
563	b.l18x1	g.h2x11	2.96438	Yes	Yes	8	6	6
564	b.l18x1	g.h2x12	2.4425	Yes	No	0	6	7
565	b.b22x5	b.l18x2	2.43563	Yes	Yes	8	7	7
566	b.l18x2	b.l22x4	3.5525	Yes	No	8	7	9
567	b.l18x2	g.h2x11	6.51625	Yes	Yes	8	7	6
568	b.l18x3	b.l18x5	8.94125	Yes	No	0	5	2
569	b.l18x3	g.h2x8	2.3175	Yes	No	8	5	7
570	b.l18x3	g.h2x11	9.23063	Yes	Yes	8	5	6
571	b.l18x5	b.l20x2	9.41625	No	Yes	0	2	9
572	b.b19x1	g.h2x8	2.46187	No	No	8	6	7
573	b.b19x2	b.b19x4	2.42812	Yes	Yes	1	6	8
574	b.b19x2	b.b20x6	10.7181	Yes	Yes	1	6	6
575	b.b19x2	b.l20x1	2.3625	Yes	No	0	6	6
576	b.b19x3	b.b22x5	3.1175	No	Yes	0	4	7
577	b.b19x4	b.b20x6	6.97062	Yes	Yes	1	8	6
578	b.b19x5	b.l21x9	4.95937	No	No	0	5	6
579	b.b19x6	b.l19x2	6.44063	No	Yes	1	9	9
580	b.b20x2	b.l19x2	5.05875	Yes	Yes	1	6	9
581	b.b20x2	b.b20x4	7.03437	Yes	Yes	1	6	8
582	b.b20x2	b.b21x6	2.45312	Yes	Yes	1	6	1
583	b.b20x2	b.l21x1	4.3	Yes	No	1	6	2
584	b.b20x3	b.b21x7	3.8625	No	Yes	0	8	5
585	b.b20x3	b.l21x9	3.47687	No	No	0	8	6
586	b.b20x4	b.b20x6	4.27687	Yes	Yes	1	8	6
587	b.b20x4	b.b21x3	16.2131	Yes	No	1	8	6
588	b.b20x4	b.b21x6	7.035	Yes	Yes	1	8	1
589	b.b20x5	b.b21x4	3.54563	No	No	0	7	5
590	b.b20x5	b.b21x7	3.66438	No	Yes	0	7	5
591	b.b20x6	b.b21x3	6.415	Yes	No	1	6	6
592	b.b20x7	b.l20x3	2.8925	Yes	No	0	9	7
593	b.b20x7	b.b21x4	7.29688	Yes	No	0	9	5
594	b.b20x7	g.h2x4	3.85875	Yes	No	0	9	7
595	b.l20x2	g.l1x5	4.54187	Yes	No	0	9	4
596	b.l20x2	g.h2x7	6.775	Yes	No	0	9	5
597	b.b21x1	g.l1x4	6.62687	Yes	Yes	0	7	8
598	b.b21x2	g.h2x1	3.31437	Yes	No	0	6	8
599	b.b21x3	b.b21x6	4.49625	No	Yes	1	6	1
600	b.b21x5	b.b21x7	10.4794	Yes	Yes	1	4	5
601	b.b21x5	b.b25x1	2.61625	Yes	No	1	4	2
602	b.b21x6	b.l21x1	2.2	Yes	No	1	1	2
603	b.b21x7	b.b23x2	3.88375	Yes	No	0	5	6
604	b.b21x7	b.b24x6	6.03	Yes	Yes	1	5	8
605	b.b21x7	b.b25x1	2.58563	Yes	No	1	5	2
606	b.l21x2	b.l21x4	5.66	No	No	0	4	4
607	b.l21x2	b.l21x5	4.63812	No	Yes	1	4	4
608	b.b25x3	b.l21x2	6.27812	Yes	No	1	5	4
609	b.b23x6	b.l21x5	7.1	Yes	Yes	1	7	4
610	b.b24x4	b.l21x5	2.21187	Yes	Yes	1	6	4
611	b.b25x3	b.l21x5	2.50813	Yes	Yes	1	5	4
612	b.b23x6	b.l21x7	3.44375	Yes	No	1	7	5
613	b.l21x7	b.l23x1	3.69438	No	Yes	1	5	6
614	b.l21x7	b.l23x2	6.12437	No	No	1	5	8
615	b.l21x8	b.l23x1	3.66563	No	Yes	0	4	6
616	b.b23x6	b.l21x9	8.83813	Yes	No	0	7	6
617	b.b22x1	b.b22x2	3.2	No	No	0	8	8
618	b.b22x1	b.l23x1	3.79688	No	Yes	1	8	6
619	b.b22x1	b.l25x6	2.67	No	Yes	1	8	8
620	b.b22x2	b.b26x3	5.62813	No	Yes	0	8	6
621	b.b22x3	b.b23x2	2.235	No	No	0	6	6
622	b.b22x4	b.b26x3	3.37563	No	Yes	0	5	6
623	b.b22x4	b.b26x5	3.94062	No	No	0	5	7
624	b.b22x5	b.b23x2	7.45875	Yes	No	0	7	6
625	b.b23x1	b.l22x1	3.1875	Yes	No	0	5	9
626	b.l22x1	g.ctx3	7.5425	No	Yes	0	9	9
627	b.l22x3	g.ctx3	9.38875	No	Yes	0	9	9
628	b.b24x7	b.l22x5	13.77	No	Yes	11	9	9
629	b.l22x5	b.l24x2	8.80437	Yes	Yes	0	9	6
630	b.l22x5	g.ctx6	5.5425	Yes	Yes	11	9	6
631	b.b23x1	b.b24x5	5.5875	Yes	No	0	5	5
632	b.b23x1	g.ctx6	3.02875	Yes	Yes	0	5	6
633	b.b23x3	b.b24x5	4.56312	No	No	0	7	5
634	b.b23x3	b.b26x3	3.7175	No	Yes	0	7	6
635	b.b23x3	b.b27x1	2.70062	No	No	0	7	6
636	b.b23x4	b.b23x6	5.00562	No	Yes	0	6	7
637	b.b23x5	b.b24x3	2.5725	No	No	0	7	5
638	b.b23x5	b.l25x7	2.53	No	No	0	7	7
639	b.b23x6	b.l23x2	5.175	Yes	No	1	7	8
640	b.b23x6	b.b24x4	10.5381	Yes	Yes	1	7	6
641	b.b23x6	b.b24x6	6.93438	Yes	Yes	1	7	8
642	b.l23x1	b.l25x6	18.1656	Yes	Yes	1	6	8
643	b.b24x1	b.l25x5	3.6225	No	No	0	4	7
644	b.b24x2	b.b24x4	2.64062	Yes	Yes	1	5	6
645	b.b24x2	b.b25x6	4.24625	Yes	No	1	5	3
646	b.b24x3	b.b25x7	2.3825	No	No	0	5	7
647	b.b24x3	b.b26x3	2.38188	No	Yes	0	5	6
648	b.b24x4	b.b24x6	4.87313	Yes	Yes	1	6	8
649	b.b24x4	b.b25x3	10.1706	Yes	Yes	1	6	5
650	b.b24x4	b.b25x6	3.96937	Yes	No	1	6	3
651	b.b24x5	b.b25x5	2.415	No	No	0	5	4
652	b.b24x6	b.b25x3	4.93687	Yes	Yes	1	8	5
653	b.b24x7	b.l24x3	9.33438	No	Yes	0	9	5
654	b.l24x2	g.h2x12	4.5625	Yes	No	0	6	7
655	b.b25x2	b.l24x3	5.35687	No	Yes	0	2	5
656	b.b25x3	b.b25x6	2.61875	Yes	No	1	5	3
657	b.b25x7	b.b28x6	19.4331	No	Yes	0	7	9
658	b.l25x3	b.l25x7	4.2375	Yes	No	9	9	7
659	b.b27x3	b.l25x3	7.10188	No	Yes	0	8	9
660	b.b27x5	b.l25x3	13.5975	No	Yes	9	9	9
661	b.l25x3	b.l28x2	6.61687	Yes	Yes	9	9	9
662	b.b28x4	b.l25x3	8.76062	Yes	Yes	9	6	9
663	b.l25x4	b.l28x2	4.32313	No	Yes	0	5	9
664	b.l25x5	b.l28x1	7.98063	No	Yes	0	7	9
665	b.l25x6	b.l28x1	19.0525	Yes	Yes	1	8	9
666	b.b26x1	b.l28x1	5.17188	No	Yes	0	9	9
667	b.b26x3	b.b27x3	2.57688	Yes	No	0	6	8
668	b.b26x5	b.b27x1	4.71	No	No	0	7	6
669	b.l27x1	b.l27x3	5.69312	No	No	3	7	7
670	b.l27x3	b.l27x5	7.71	No	No	0	7	5
671	b.l27x5	g.ctx4	5.66062	No	No	0	5	7
672	b.l27x5	g.ctx15	4.61	No	Yes	0	5	9
673	b.l27x6	g.ctx16	3.72687	No	Yes	0	7	8
674	b.b27x1	g.ctx5	2.88687	No	No	0	6	9
675	b.b27x3	b.b28x6	8.56375	No	Yes	0	8	9
676	b.b27x4	b.b28x3	2.77875	No	Yes	0	5	7
677	b.b27x5	b.l28x2	6.62687	No	Yes	9	9	9
678	b.b28x2	b.l28x2	9.03	No	Yes	0	4	9
679	b.b28x4	b.b28x6	6.3075	Yes	Yes	9	6	9
680	b.b28x5	g.ctx16	3.53312	No	Yes	3	5	8
681	b.b28x7	g.ctx14	9.28188	No	Yes	3	9	9
682	b.b28x7	g.ctx16	5.13438	No	Yes	3	9	8
683	g.h1x10	g.h1x14	3.26562	Yes	No	0	9	9
684	g.l1x2	g.l1x4	3.60125	No	Yes	0	2	8
685	g.h2x3	g.l1x5	4.18062	No	No	0	5	4
686	g.h2x3	g.h2x7	9.2475	No	No	0	5	5
687	g.h2x11	g.h2x15	13.635	Yes	No	0	6	6
688	g.h2x14	g.h2x15	2.2875	No	No	0	4	6
689	g.ctx2	g.h2x15	3.84438	No	No	0	3	6
690	g.ctx3	g.ctx4	4.22625	Yes	No	0	9	7
691	g.ctx3	g.ctx5	3.26813	Yes	No	0	9	9
692	g.ctx3	g.ctx6	10.6788	Yes	Yes	0	9	6
693	g.ctx7	g.ctx8	3.14937	No	No	0	4	8
694	g.ctx10	g.ctx9	2.97937	No	No	3	5	6
695	g.ctx13	g.ctx9	2.85313	No	No	3	5	6
696	g.ctx14	g.ctx9	3.69312	Yes	No	3	9	6
697	g.ctx10	g.ctx13	5.90688	No	No	3	5	5
698	g.ctx12	g.ctx13	2.4325	No	No	0	6	5
699	g.ctx14	g.ctx15	4.89	Yes	Yes	3	9	9
700	g.ctx14	g.ctx16	2.645	Yes	Yes	3	9	8
701	g.ctx15	g.ctx16	3.78937	Yes	Yes	3	9	8
702	2x60	Lig	12.4494	No	Yes	2	6	0
703	3x32	Lig	5.30812	Yes	Yes	2	6	0
704	7x38	Lig	6.69313	No	Yes	2	5	0
705	Lig	Lig	226.978	Yes	Yes	2	0	0
706	6x58	Lig	4.8025	No	Yes	2	3	0
707	7x31	Lig	5.73625	No	Yes	0	3	0
708	7x34	Lig	5.46688	No	Yes	2	4	0
709	1x28	Lig	3.08375	No	Yes	0	2	0
710	2x63	Lig	2.55125	Yes	Yes	2	5	0
711	E2	Lig	29.2163	Yes	Yes	2	3	0
712	7x35	Lig	2.76188	No	Yes	2	3	0
713	Lig	NT	26.2206	Yes	Yes	2	0	5
714	E2x51	Lig	16.6906	No	Yes	2	4	0
715	5x32	Lig	3.88437	No	Yes	2	2	0
716	6x61	Lig	5.91438	No	Yes	2	2	0
717	NT	NT	7.09688	Yes	Yes	2	5	5
718	7x24	NT	2.73	No	Yes	0	8	5
719	1x27	7x28	2.31562	No	Yes	0	4	2
720	1x35	1x39	10.9475	No	Yes	0	5	7
721	1x35	7x35	2.58562	No	No	0	5	3
722	1x36	2x65	2.815	No	No	0	5	3
723	1x38	7x39	2.82125	No	No	0	5	5
724	1x39	2x61	3.14	Yes	No	0	7	7
725	1x39	7x39	4.9	Yes	No	0	7	5
726	1x39	7x42	4.925	Yes	Yes	0	7	6
727	1x42	7x47	3.07	No	No	0	7	8
728	1x43	1x47	3.11	No	No	0	5	6
729	1x43	2x57	2.41125	No	Yes	2	5	7
730	1x43	2x58	7.57312	No	No	2	5	8
731	1x46	1x50	2.29938	No	No	0	8	9
732	1x46	2x54	3.06063	No	No	0	8	6
733	1x47	2x51	2.84938	No	No	0	6	7
734	1x48	1x49	3.57562	No	No	0	3	7
735	1x50	2x50	12.2838	No	Yes	0	9	9
736	1x50	7x50	8.65313	No	Yes	0	9	9
737	1x53	2x47	2.86188	No	No	0	9	8
738	1x53	7x54	5.07125	No	No	0	9	7
739	1x54	2x44	2.50812	No	No	16	7	6
740	1x54	2x48	2.43687	No	No	16	7	6
741	1x56	8x50	4.48312	No	Yes	0	7	8
742	1x57	2x44	4.01375	No	No	0	7	6
743	1x59	8x57	2.28875	Yes	No	0	4	5
744	1x60	8x53	6.54188	No	No	0	4	4
745	2x37	2x40	4.38625	No	Yes	0	7	8
746	2x38	2x42	5.36063	Yes	Yes	2	7	7
747	2x38	3x49	2.8175	Yes	Yes	2	7	8
748	2x38	I2x57	4.1375	Yes	No	2	7	7
749	2x38	4x42	2.64875	Yes	No	2	7	7
750	2x39	3x49	3.29562	No	Yes	0	8	8
751	2x41	4x42	3.26625	No	No	0	6	7
752	2x42	3x45	8.5075	Yes	No	0	7	7
753	2x42	3x46	4.36625	Yes	No	2	7	9
754	2x42	3x49	4.75	Yes	Yes	2	7	8
755	2x42	4x42	4.74312	Yes	No	2	7	7
756	2x42	4x45	3.76875	Yes	No	0	7	5
757	2x43	7x54	3.60625	No	No	0	8	7
758	2x45	3x42	6.30375	No	Yes	2	9	7
759	2x45	4x46	9.58813	No	No	2	9	7
760	2x45	4x50	3.88438	No	Yes	2	9	9
761	2x46	2x50	3.9875	Yes	Yes	2	9	9
762	2x46	3x42	3.4325	Yes	Yes	2	9	7
763	2x46	3x43	3.05687	Yes	No	2	9	8
764	2x46	7x49	4.28875	Yes	Yes	2	9	9
765	2x49	3x38	3.1475	No	No	2	8	7
766	2x49	4x50	3.24125	No	Yes	2	8	9
767	2x50	3x39	3.24063	Yes	No	0	9	9
768	2x50	7x46	5.90812	Yes	No	0	9	9
769	2x50	7x49	6.395	Yes	Yes	2	9	9
770	2x53	2x57	2.9575	Yes	Yes	2	6	7
771	2x53	3x32	8.30062	Yes	Yes	2	6	6
772	2x53	3x35	4.81187	Yes	No	0	6	8
773	2x53	7x42	5.35312	Yes	Yes	2	6	6
774	2x53	7x46	4.53062	Yes	No	0	6	9
775	2x56	3x31	5.36063	No	No	0	6	5
776	2x56	3x32	2.26188	No	Yes	0	6	6
777	2x57	2x58	2.905	Yes	No	2	7	8
778	2x57	2x61	2.22938	Yes	No	0	7	7
779	2x59	E1x52	4.83313	No	Yes	2	6	7
780	2x59	3x24	3.54125	No	No	2	6	6
781	2x59	3x28	5.30125	No	No	2	6	5
782	2x60	2x63	4.59188	No	Yes	2	6	5
783	2x62	2x66	2.86625	No	No	0	4	4
784	2x62	E1x52	3.7325	No	Yes	0	4	7
785	2x63	E1x50	9.54062	Yes	Yes	2	5	8
786	2x67	E2	5.07625	No	Yes	2	3	3
787	E1x49	E1x51	2.23813	No	No	0	4	3
788	E1x49	E2	9.65375	No	Yes	2	4	3
789	E1x50	E1x52	16.9112	Yes	Yes	2	8	7
790	3x25	E1x50	6.69563	Yes	Yes	2	9	8
791	E1x50	E2	3.06063	Yes	Yes	2	8	3
792	E1x50	E2x50	7.26188	Yes	No	2	8	9
793	E1x51	E1x52	5.36438	No	Yes	0	3	7
794	3x24	E1x52	3.1725	No	Yes	2	6	7
795	3x22	3x26	4.02375	No	No	0	3	7
796	3x22	E2	7.92437	No	Yes	2	3	3
797	3x24	3x28	2.80875	No	No	2	6	5
798	3x25	4x65	2.21187	Yes	Yes	2	9	4
799	3x25	E2	3.34125	Yes	Yes	2	9	3
800	3x25	E2x50	7.16625	Yes	No	2	9	9
801	3x27	3x31	4.33438	No	No	17	5	5
802	3x29	4x65	15.51	No	Yes	0	5	4
803	3x30	4x57	4.00938	Yes	No	0	5	7
804	3x30	4x62	11.7444	Yes	No	0	5	4
805	3x32	3x33	3.09625	Yes	Yes	2	6	4
806	3x33	4x57	2.99	Yes	No	0	4	7
807	3x33	4x61	4.11375	Yes	No	0	4	5
808	3x34	4x50	4.82375	No	Yes	0	5	9
809	3x34	4x54	3.67438	No	No	0	5	4
810	3x34	4x57	5.03312	No	No	0	5	7
811	3x36	6x48	6.0825	No	Yes	2	7	9
812	3x37	4x56	5.93938	Yes	No	0	7	5
813	3x37	5x43	3.8525	Yes	No	2	7	4
814	3x38	4x50	9.92688	No	Yes	2	7	9
815	3x38	4x53	3.05937	No	No	0	7	8
816	3x40	5x50	2.82312	No	Yes	2	8	9
817	3x40	6x48	4.25625	No	Yes	2	8	9
818	3x41	4x49	4.30562	No	No	0	5	7
819	3x42	4x46	2.21187	Yes	No	2	7	7
820	3x42	4x49	6.4225	Yes	No	0	7	7
821	3x42	4x50	4.14313	Yes	Yes	2	7	9
822	3x43	7x49	3.11937	No	Yes	2	8	9
823	3x43	7x53	7.31563	No	Yes	2	8	9
824	3x44	5x50	4.02	No	Yes	0	7	9
825	3x44	5x53	4.87375	No	No	0	7	7
826	3x45	4x49	4.38438	No	No	0	7	7
827	3x46	7x53	4.12375	No	Yes	2	9	9
828	3x47	5x54	4.725	No	Yes	2	9	8
829	3x47	5x57	4.71562	No	No	0	9	8
830	3x47	5x58	6.9725	No	Yes	2	9	9
831	3x49	I2x57	11.435	Yes	No	2	8	7
832	3x50	5x58	7.39437	Yes	Yes	2	9	9
833	3x50	7x53	5.5925	Yes	Yes	2	9	9
834	3x51	3x55	7.18438	Yes	Yes	14	8	8
835	3x51	3x56	2.46	Yes	No	14	8	6
836	3x51	5x57	7.085	Yes	No	0	8	8
837	3x51	5x61	2.5525	Yes	No	0	8	8
838	3x54	5x61	4.92438	No	No	0	9	8
839	3x55	3x56	2.88063	Yes	No	14	8	6
840	3x55	5x64	4.875	Yes	No	0	8	5
841	I2x52	I2x56	12.2669	No	No	0	5	4
842	I2x53	I2x57	2.92688	No	No	0	5	7
843	4x38	4x40	3.0275	No	No	0	7	3
844	4x38	4x41	3.32188	No	Yes	0	7	4
845	4x39	4x43	3.02	No	No	0	1	4
846	4x59	4x60	2.84438	No	No	0	4	7
847	4x63	4x64	3.9475	No	Yes	0	4	5
848	4x64	E2	13.6325	Yes	Yes	2	5	3
849	4x64	5x35	5.29562	Yes	Yes	2	5	1
850	4x65	E2x50	5.05125	Yes	No	2	4	9
851	4x65	E2x52	6.69875	Yes	No	2	4	4
852	E2	E2	37.1281	Yes	Yes	2	3	3
853	E2	E2x51	8.38313	Yes	No	2	3	4
854	E2	E2x52	3.06437	Yes	No	2	3	4
855	5x32	E2	4.51875	No	Yes	2	2	3
856	5x35	E2	7.8675	Yes	Yes	2	1	3
857	5x39	E2	3.12312	No	Yes	0	5	3
858	5x31	E2	4.39563	No	Yes	2	5	3
859	5x31	5x35	4.66625	No	Yes	2	5	1
860	5x36	6x59	4.70062	Yes	Yes	2	4	5
861	5x37	6x59	3.99375	No	Yes	2	1	5
862	5x38	5x42	3.64562	No	No	0	4	3
863	5x40	6x55	2.7025	No	No	0	5	5
864	5x40	6x59	4.78125	No	Yes	2	5	5
865	5x41	5x45	2.89313	No	No	0	4	5
866	5x44	6x52	4.7475	No	No	0	5	8
867	5x47	5x51	3.06812	Yes	No	2	8	6
868	5x47	6x49	4.06812	Yes	Yes	2	8	6
869	5x47	6x52	8.41125	Yes	No	2	8	8
870	5x49	5x50	3.54625	No	Yes	0	6	9
871	5x49	5x53	2.3625	No	No	0	6	7
872	5x50	6x44	3.55312	Yes	Yes	2	9	9
873	5x51	6x44	4.13188	No	Yes	2	6	9
874	5x51	6x45	2.28	No	Yes	2	6	6
875	5x54	5x58	3.24437	Yes	Yes	2	8	9
876	5x54	6x41	2.26938	Yes	No	2	8	8
877	5x54	6x44	3.7375	Yes	Yes	2	8	9
878	5x58	5x61	2.65688	Yes	No	0	9	8
879	5x58	6x37	8.54938	Yes	No	0	9	7
880	5x58	6x40	4.5575	Yes	No	2	9	8
881	5x58	6x41	3.43375	Yes	No	2	9	8
882	5x62	6x34	4.0775	Yes	No	0	5	7
883	5x62	6x37	4.14563	Yes	No	0	5	7
884	5x64	5x67	5.02938	No	No	0	5	4
885	5x65	6x33	2.5275	Yes	No	10	7	7
886	5x65	6x34	4.46875	Yes	No	0	7	7
887	6x31	6x35	2.37437	No	No	0	5	5
888	6x36	7x56	6.67562	No	No	0	8	7
889	6x39	7x52	3.5375	No	No	0	6	8
890	6x40	7x52	3.39688	No	No	2	8	8
891	6x40	7x53	5.94625	No	Yes	2	8	9
892	6x43	6x47	2.24813	No	No	0	6	8
893	6x43	7x48	3.47687	No	No	0	6	6
894	6x44	6x48	11.0112	Yes	Yes	2	9	9
895	6x45	6x49	8.41438	Yes	Yes	2	6	6
896	6x47	7x45	6.99437	No	No	0	8	9
897	6x48	6x52	3.81063	Yes	No	2	9	8
898	6x48	7x45	10.735	Yes	No	0	9	9
899	6x49	6x50	3.40625	Yes	No	0	6	9
900	6x50	7x37	2.68438	No	No	0	9	7
901	6x51	6x55	10.5188	Yes	No	0	6	5
902	6x51	7x37	3.2175	Yes	No	0	6	7
903	6x51	7x38	4.69875	Yes	No	2	6	5
904	6x54	7x34	4.4625	No	No	0	4	4
905	6x54	7x37	2.57	No	No	0	4	7
906	6x57	7x30	3.56625	No	Yes	2	5	4
907	6x58	7x30	3.2425	No	Yes	2	3	4
908	6x61	7x30	2.39563	No	Yes	2	2	4
909	E3	E3	2.81375	Yes	Yes	2	1	1
910	7x38	7x42	3.09562	No	Yes	2	5	6
911	7x45	7x49	2.19438	No	Yes	0	9	9
912	7x49	7x50	2.75	Yes	Yes	0	9	9
913	7x49	7x53	3.92625	Yes	Yes	2	9	9
914	7x51	7x55	3.54813	No	Yes	0	6	7
915	7x52	7x53	2.55	No	Yes	2	8	9
916	7x54	8x50	3.11937	No	Yes	0	7	8
917	7x55	8x50	12.9263	Yes	Yes	0	7	8
918	8x50	8x54	3.77437	Yes	No	0	8	5
919	1x29	1x33	4.65438	No	No	0	4	3
920	1x52	7x55	2.51438	No	Yes	0	6	7
921	2x43	7x53	2.27688	No	Yes	0	8	9
922	2x44	2x48	2.54875	No	No	16	6	6
923	2x54	7x46	3.3925	No	No	0	6	9
924	2x55	2x56	4.03	No	No	0	5	6
925	2x57	7x42	6.18563	Yes	Yes	2	7	6
926	3x33	3x37	2.89188	Yes	Yes	2	4	7
927	3x33	5x43	3.715	Yes	No	2	4	4
928	3x36	3x37	6.38937	No	Yes	2	7	7
929	3x40	6x44	2.85375	No	Yes	2	8	9
930	3x54	5x64	2.29437	No	No	0	9	5
931	3x55	5x60	2.68563	Yes	No	14	8	4
932	G.hns1.03	I2x55	3.47875	No	No	0	4	4
933	4x38	G.HN.52	2.39563	No	No	0	7	4
934	4x61	4x65	3.31312	No	Yes	0	5	4
935	E2x52	Lig	7.56625	No	Yes	2	4	0
936	5x36	E2	9.91125	Yes	Yes	2	4	3
937	5x32	5x35	3.01	No	Yes	2	2	1
938	5x33	5x37	2.45875	No	No	2	1	1
939	5x36	Lig	4.78938	Yes	Yes	2	4	0
940	5x65	G.H5.26	2.81625	Yes	Yes	10	7	5
941	5x68	I3	3.98812	No	Yes	0	0	4
942	G.h4s6.12	I3	2.55375	No	Yes	10	4	4
943	6x32	7x56	3.36375	No	No	0	7	7
944	6x36	G.H5.25	2.40312	No	Yes	0	8	7
945	6x48	7x41	3.20437	Yes	No	0	9	7
946	6x61	E3	4.04437	No	Yes	2	2	1
947	7x26	E3	5.19	No	Yes	2	1	1
948	7x27	Lig	5.34625	No	Yes	0	3	0
949	G.S1.05	G.S1.07	4.58687	Yes	Yes	1	9	9
950	G.H1.03	G.H1.07	2.39125	No	No	0	9	9
951	G.H1.04	G.H1.07	2.57375	Yes	No	0	7	9
952	G.hfs2.06	b.l7x4	2.37563	No	Yes	0	7	9
953	G.H2.05	G.H2.06	3.95062	No	Yes	1	8	9
954	G.H2.05	b.l17x6	3.88938	No	Yes	1	8	9
955	G.S4.06	G.S5.06	2.32812	Yes	Yes	0	7	8
956	G.h3s5.01	G.h3s5.02	3.07188	No	No	0	3	4
957	G.HG.03	G.s5hg.01	4.75875	Yes	No	1	6	9
958	G.H5.02	G.s6h5.04	3.93937	No	No	0	4	8
959	b.1x13	b.1x16	2.26312	No	No	0	4	2
960	b.1x15	b.1x19	3.99063	No	No	0	4	2
961	b.1x19	b.b21x1	8.26312	No	Yes	0	2	7
962	b.b21x2	b.lh12x1	3.69688	Yes	No	0	6	3
963	b.lhb1x1	b.lhb1x2	2.46813	No	No	0	1	1
964	b.b7x4	b.b8x2	2.58	Yes	No	5	8	8
965	b.l7x5	b.l9x1	2.43563	Yes	No	0	6	5
966	b.b8x3	b.b9x4	2.40562	Yes	Yes	0	6	9
967	b.b11x1	b.l10x2	6.36563	No	No	0	5	5
968	b.b11x6	b.b12x2	3.2	Yes	Yes	1	9	7
969	b.l13x3	b.l15x2	4.41	Yes	Yes	6	9	9
970	b.b15x5	b.l15x2	2.70312	No	Yes	6	8	9
971	b.b24x2	b.l23x2	10.7694	Yes	No	1	5	8
972	b.b27x5	b.l25x7	3.33437	No	No	9	9	7
973	G.H5.14	G.h2s4.05	2.37875	No	No	0	7	7
974	G.H5.02	G.s6h5.05	2.5925	No	No	0	4	9
975	b.l12x2	b.l12x3	2.99688	No	Yes	13	6	5
976	1x42	7x42	3.55625	No	Yes	0	7	6
977	1x55	1x59	3.66687	No	Yes	0	4	4
978	1x58	1x59	2.57562	No	Yes	0	4	4
979	8x53	I1x48	2.69937	No	No	0	4	6
980	2x41	4x43	4.80188	No	No	0	6	4
981	3x51	5x60	3.46812	Yes	No	14	8	4
982	5x47	6x48	2.96875	Yes	Yes	2	8	9
983	6x51	Lig	5.68375	Yes	Yes	2	6	0
984	6x57	E3	3.3025	No	Yes	2	5	1
985	7x48	7x51	2.62563	No	No	0	6	6
986	5x43	Lig	2.32687	No	Yes	2	4	0
987	1x59	1x60	4.03188	Yes	No	0	4	4
988	2x52	3x35	3.65375	No	No	0	6	8
989	5x33	6x59	7.70875	No	Yes	2	1	5
990	5x36	6x58	4.24563	Yes	No	2	4	3
991	G.s4h3.07	G.s4h3.15	4.34188	No	No	0	0	9
992	G.H5.02	G.s6h5.02	2.3225	No	No	0	4	7
993	G.H5.23	G.H5.24	2.205	No	No	0	4	8
994	b.l24x3	b.lhb1x3	4.81875	Yes	Yes	0	5	2
995	G.H5.17	I3	4.945	No	Yes	10	5	4
996	2x63	E1	6.44688	Yes	No	2	5	0
997	E1	Lig	6.27437	No	Yes	2	0	0
998	3x46	3x50	3.36438	No	Yes	2	9	9
999	5x36	5x40	4.51813	Yes	No	2	4	5
1000	5x47	6x45	3.15812	Yes	Yes	2	8	6
1001	5x65	I3	4.01	Yes	Yes	10	7	4
1002	6x60	E3	3.61438	No	Yes	2	4	1
1003	1x29	1x32	6.5825	No	No	0	4	4
1004	3x33	3x36	2.26125	Yes	No	2	4	7
1005	3x37	5x461	2.6225	Yes	No	0	7	6
1006	5x47	6x44	2.81375	Yes	Yes	2	8	9
1007	b.1x10	b.1x11	2.49375	No	Yes	0	8	6
1008	b.1x10	b.1x14	2.24	No	No	0	8	7
1009	b.1x19	b.b21x2	3.7225	No	Yes	0	2	6
1010	2x66	E1x51	2.36875	No	No	0	4	3
1011	8x52	8x53	3.19937	No	No	0	5	4
1012	1x44	1x48	2.52813	No	No	0	6	3
1013	2x40	8x49	2.42562	Yes	No	0	8	6
1014	7x50	7x55	2.34562	Yes	Yes	0	9	7
1015	1x61	2x40	5.055	No	Yes	0	0	8
1016	2x64	E1	2.67	No	No	0	4	0
1017	3x27	3x30	2.51	No	Yes	17	5	5
1018	3x30	3x31	2.435	Yes	No	17	5	5
1019	5x29	E2	2.21	No	Yes	2	0	3
1020	5x67	5x68	3.615	No	No	0	4	0
1021	7x30	Lig	3.61	Yes	Yes	2	4	0
1022	b.1x7	g.h1x7	9.275	No	No	0	5	2
1023	b.1x11	g.h1x10	3.995	Yes	Yes	0	6	9
1024	b.1x12	g.h1x10	2.71	No	Yes	0	1	9
1025	g.h1x1	g.h1x3	4.115	No	Yes	0	2	3
1026	g.h1x10	g.h1x6	7.46	Yes	No	0	9	4
1027	G.H1.09	G.H1.10	2.91	No	No	0	7	0
1028	G.HN.45	G.HN.49	2.18062	No	No	0	4	4
1029	b.b10x5	b.b6x4	2.16437	Yes	No	0	9	7
1030	b.b13x1	b.l12x3	2.16125	No	Yes	0	4	5
1031	1x61	I1	2.16	No	No	0	0	0
1032	b.l27x4	g.ctx4	2.15688	No	No	0	9	7
1033	6x50	7x40	2.1525	No	No	0	9	8
1034	1x45	1x48	2.15125	No	No	0	6	3
1035	G.HN.43	b.b5x6	2.12875	Yes	No	0	9	6
1036	b.1x18	g.l1x4	2.12313	No	Yes	0	6	8
1037	2x39	G.H5.22	2.12125	No	No	0	8	4
1038	G.S3.01	I2x54	2.11438	Yes	No	0	4	5
1039	b.lhb1x4	b.lhb1x5	2.11313	No	No	0	1	1
1040	5x37	5x41	2.10875	No	No	0	1	4
1041	G.S2.02	G.S3.07	2.09875	No	Yes	0	5	9
1042	b.l22x2	g.ctx3	2.07313	No	Yes	0	1	9
1043	b.b12x2	b.l13x1	2.06063	Yes	No	0	7	2
1044	4x41	4x45	2.05438	Yes	No	0	4	5
1045	G.H5.16	G.H5.20	2.05188	No	Yes	0	6	9
1046	b.b24x2	b.l25x1	2.05	Yes	No	0	5	3
1047	G.HN.52	G.hns1.03	2.03562	No	No	0	4	4
1048	b.b2x2	b.b6x3	2.03437	No	No	0	7	8
1049	b.l27x2	b.l2x4	2.02187	No	No	0	1	5
1050	b.b28x6	b.l25x2	2.02062	Yes	No	0	9	5
1051	I2x55	I2x56	2.01	No	No	0	4	4
1052	b.b21x7	b.l24x1	2.00125	Yes	No	0	5	5
1053	G.h4s6.09	G.h4s6.10	1.99	No	No	0	3	3
1054	4x60	4x64	1.98688	No	Yes	0	7	5
1055	2x48	2x52	1.98062	No	No	0	6	6
1056	1x56	1x60	1.97938	No	No	0	7	4
1057	5x55	6x41	1.97625	No	No	0	4	8
1058	b.1x13	b.1x9	1.97	No	No	0	4	1
1059	5x34	5x35	1.93875	No	Yes	0	1	1
1060	b.l13x1	b.l13x2	1.93375	No	No	0	2	6
1061	b.b12x1	b.l13x5	1.93375	No	No	0	6	5
1062	G.HN.51	b.l1x4	1.92375	No	No	0	5	6
1063	6x62	Lig	1.92375	No	Yes	0	3	0
1064	b.b18x4	b.b22x5	1.92125	No	Yes	0	3	7
1065	6x54	7x33	1.91563	No	No	0	4	6
1066	3x37	5x42	1.9025	Yes	No	0	7	3
1067	5x44	6x56	1.8975	No	No	0	5	6
1068	b.b12x6	b.l9x2	1.84812	Yes	No	0	8	5
1069	5x56	5x60	1.845	No	No	0	4	4
1070	b.h2x4	g.h2x5	1.82437	No	No	0	3	6
1071	b.b25x4	b.lhb1x9	1.82437	No	Yes	0	4	3
1072	6x47	7x43	1.82312	No	No	0	8	5
1073	1x37	1x41	1.8025	No	No	0	5	5
1074	b.h2x2	b.lh12x4	1.8	No	No	0	1	3
1075	3x48	5x57	1.79938	No	No	0	7	8
1076	7x28	NT	1.78938	Yes	Yes	2	2	5
1077	b.1x7	g.h1x8	1.7825	No	No	0	5	7
1078	g.ctx1	g.ctx2	1.77187	No	No	0	1	3
1079	1x47	1x51	1.7625	No	No	0	6	4
1080	G.HG.07	G.s4h3.06	1.7625	Yes	No	0	9	8
1081	5x55	5x59	1.75875	No	No	0	4	3
1082	b.l2x2	b.l6x2	1.75	No	No	0	1	6
1083	G.HG.03	G.HG.06	1.74	Yes	No	0	6	5
1084	4x41	4x44	1.73125	Yes	No	0	4	3
1085	3x48	3x52	1.72812	No	No	0	7	5
1086	G.H1.05	G.S3.05	1.71	No	Yes	0	6	7
1087	7x32	7x33	1.71	No	No	0	2	6
1088	g.h1x12	g.h1x8	1.70875	No	No	0	6	7
1089	b.h2x3	b.lh12x3	1.70812	No	No	0	1	4
1090	b.l17x1	b.l17x2	1.70625	No	No	0	2	6
1091	G.HN.32	G.HN.33	1.70562	No	No	0	5	4
1092	G.HN.42	G.HN.45	1.705	No	No	0	4	4
1093	G.s2s3.02	I2x55	1.69937	No	No	0	3	4
1094	5x45	5x48	1.68875	No	No	0	5	4
1095	6x30	6x32	1.67937	No	No	0	7	7
1096	3x21	E1x50	1.66875	No	Yes	0	7	8
1097	b.b28x1	b.l1x3	1.65313	No	Yes	0	4	9
1098	1x49	7x50	1.64937	No	Yes	0	7	9
1099	1x36	1x37	1.64812	No	No	0	5	5
1100	b.lh12x2	b.lh12x3	1.63812	Yes	No	0	8	4
1101	4x56	5x46	1.61812	No	No	0	5	5
1102	b.lhb1x6	b.lhb1x7	1.61	Yes	No	0	3	1
1103	G.S1.07	G.s1h1.01	1.60313	Yes	No	0	9	9
1104	6x45	6x46	1.60063	Yes	No	0	6	6
1105	G.HG.14	G.HG.17	1.58563	No	No	0	5	3
1106	1x24	7x28	1.58	No	Yes	0	3	2
1107	G.s4h3.08	G.s4h3.10	1.57375	No	No	0	0	0
1108	5x62	6x38	1.56125	Yes	No	0	5	5
1109	b.1x3	g.h1x1	1.54813	Yes	No	0	8	2
1110	b.b17x3	g.h1x9	1.525	No	No	0	5	6
1111	1x31	7x32	1.50625	No	No	0	1	2
1112	b.l13x2	g.h1x5	1.5	No	No	0	6	6
1113	G.H1.03	G.H1.06	1.5	No	No	0	9	9
1114	G.H3.05	G.s1h1.02	1.49625	No	No	0	9	7
1115	6x49	6x53	1.4875	Yes	No	0	6	6
1116	G.H5.21	G.H5.26	1.47312	No	Yes	0	5	5
1117	b.b12x1	b.b12x2	1.47187	No	Yes	0	6	7
1118	G.HN.45	G.HN.48	1.4675	No	No	0	4	3
1119	8x48	8x51	1.465	No	No	0	5	8
1120	8x48	8x52	1.39688	No	No	0	5	5
1121	b.1x11	g.h1x7	1.385	Yes	No	0	6	2
1122	G.H3.03	G.hgh4.01	1.3825	No	No	0	4	6
1123	6x28	G.h4s6.09	1.3825	No	No	0	4	3
1124	1x41	1x45	1.35	No	No	0	5	6
1125	G.s1h1.03	G.s1h1.04	1.3325	No	No	0	8	9
1126	I1x49	I1x50	1.31875	No	No	0	5	7
1127	b.b20x1	b.l21x5	1.31687	No	Yes	0	5	4
1128	7x29	7x30	1.31	No	Yes	0	3	4
1129	g.h3x11	g.h3x15	1.28625	No	No	0	0	0
1130	G.H4.13	G.H4.17	1.26437	No	No	0	3	4
1131	3x41	4x52	1.25375	No	No	0	5	4
1132	G.HN.53	G.hns1.03	1.2375	No	No	0	1	4
1133	2x40	I1x51	1.22563	Yes	No	0	8	6
1134	1x30	1x33	1.22063	No	No	0	6	3
1135	b.1x22	g.l1x4	1.2175	No	Yes	0	0	8
1136	6x32	6x35	1.195	No	No	0	7	5
1137	7x23	7x26	1.19187	No	No	0	4	1
1138	1x32	2x67	1.19	No	No	0	4	3
1139	G.H3.04	G.H3.07	1.18125	No	No	0	9	5
1140	I1x49	b.l25x4	1.1775	No	No	0	5	5
1141	G.HG.09	G.HG.12	1.16875	No	No	0	2	1
1142	b.1x14	g.h1x15	1.1525	No	No	0	7	8
1143	G.S2.04	G.S3.05	1.13063	No	Yes	0	6	7
1144	g.h2x13	g.h2x9	1.13	No	No	0	1	4
1145	4x48	4x52	1.12312	No	No	0	3	4
1146	g.ctx6	g.ctx7	1.1025	Yes	No	0	6	4
1147	b.1x2	b.1x3	1.09625	No	Yes	0	1	8
1148	6x60	6x63	1.0925	No	No	0	4	1
1149	g.ctx6	g.h2x16	1.08563	Yes	No	0	6	4
1150	G.H1.02	G.H1.06	1.0825	No	No	0	9	9
1151	b.1x1	b.1x5	1.07375	No	No	0	1	3
1152	g.h1x3	g.h1x4	1.045	Yes	No	0	3	5
1153	5x52	5x56	1.01813	No	No	0	3	4
1154	g.h3x6	g.h3x9	1.0175	No	No	0	0	0
1155	6x57	6x64	1.01562	No	No	0	5	1
1156	b.l18x1	g.h3x8	1.005	Yes	No	0	6	0
1157	1x25	Lig	1.005	No	Yes	0	1	0
1158	b.1x8	g.h1x7	0.9875	No	No	0	4	2
1159	g.h1x15	g.l1x1	0.975	No	No	0	8	1
1160	b.1x3	b.1x6	0.963125	Yes	No	0	8	8
1161	8x56	b.l25x4	0.950625	No	No	0	4	5
1162	6x42	6x43	0.945625	No	No	0	5	6
1163	G.HN.52	I2x58	0.945	No	No	0	4	0
1164	b.l20x2	g.h3x7	0.945	Yes	No	0	9	0
1165	G.H4.17	G.h4s6.01	0.934375	No	Yes	0	4	4
1166	G.HN.11	G.HN.37	0.93125	Yes	No	0	2	3
1167	G.HG.05	G.HG.09	0.928125	No	No	0	5	2
1168	b.l8x5	b.l8x6	0.9225	Yes	No	0	3	4
1169	7x23	7x25	0.91	No	No	0	4	1
1170	1x40	2x61	0.880625	No	No	0	5	7
1171	5x59	5x63	0.878125	No	No	0	3	4
1172	G.HN.30	G.HN.31	0.855	No	No	0	7	1
1173	b.l1x4	b.l3x2	0.84875	No	Yes	0	6	9
1174	3x22	3x23	0.84	No	No	0	3	1
1175	b.1x4	g.h1x8	0.838125	No	No	0	3	7
1176	b.h2x3	b.lhb1x1	0.825	No	No	0	1	1
1177	8x47	8x48	0.82	No	No	0	8	5
1178	5x29	5x30	0.805	No	No	0	0	0
1179	b.1x2	b.b21x2	0.803125	No	Yes	0	1	6
1180	G.s4h3.11	G.s4h3.14	0.779375	No	No	0	0	6
1181	G.H1.09	G.S2.06	0.775	No	No	0	7	9
1182	g.h2x6	g.h2x7	0.77	No	No	0	2	5
1183	b.l21x3	b.l21x4	0.7575	No	No	0	3	4
1184	G.H4.04	G.H4.08	0.755	No	No	0	4	3
1185	G.H1.11	G.S2.05	0.74625	No	Yes	0	0	3
1186	b.1x4	b.ntx2	0.745625	No	No	0	3	5
1187	b.1x2	b.1x5	0.744375	No	No	0	1	3
1188	4x51	4x55	0.736875	No	No	0	4	4
1189	b.l22x3	g.l3x4	0.73625	No	No	0	9	0
1190	G.HN.51	G.hns1.01	0.73125	No	No	0	5	3
1191	b.b16x1	b.l17x3	0.73	No	Yes	0	4	9
1192	b.l18x3	g.h3x11	0.726875	Yes	No	0	5	0
1193	b.1x12	b.1x13	0.7	No	No	0	1	4
1194	1x35	7x36	0.69	No	No	0	5	6
1195	b.lhb1x3	g.h3x13	0.683125	Yes	No	0	2	0
1196	G.HG.02	G.s6h5.03	0.6625	No	No	0	9	9
1197	G.hfs2.04	G.hfs2.05	0.656875	No	No	0	0	0
1198	b.l24x2	g.h3x12	0.651875	Yes	No	0	6	0
1199	g.h3x10	g.h3x6	0.649375	No	No	0	0	0
1200	G.s3h2.01	G.s3h2.02	0.649375	No	No	0	9	9
1201	5x62	5x66	0.649375	Yes	No	0	5	4
1202	G.H2.01	G.s3h2.02	0.64875	No	No	0	9	9
1203	8x51	8x55	0.643125	No	No	0	8	5
1204	1x34	1x38	0.6175	No	No	0	6	5
1205	6x65	7x30	0.60875	No	Yes	0	1	4
1206	b.1x16	b.1x17	0.595	No	No	0	2	4
1207	b.1x4	b.ntx1	0.58	No	No	0	3	5
1208	G.H3.04	G.s4h3.14	0.539375	No	No	0	9	6
1209	1x59	8x60	0.51625	Yes	No	0	4	5
1210	G.h2s4.02	G.h2s4.03	0.5125	No	No	0	7	5
1211	g.h3x14	g.h3x15	0.50875	No	No	0	0	0
1212	G.HN.38	G.HN.41	0.50625	No	No	0	3	4
1213	G.HN.34	G.HN.38	0.50625	No	No	0	3	3
1214	b.b17x5	g.l2x1	0.499375	Yes	No	0	7	0
1215	G.HN.09	G.HN.11	0.49625	No	Yes	0	5	2
1216	b.b20x7	g.h3x4	0.48625	Yes	No	0	9	0
1217	1x59	8x61	0.47625	Yes	No	0	4	0
1218	b.lh12x2	g.h3x2	0.46	Yes	No	0	8	0
1219	b.b21x2	g.h3x1	0.4475	Yes	No	0	6	0
1220	b.b21x1	g.l2x3	0.446875	Yes	No	0	7	0
1221	G.s4h3.07	G.s4h3.12	0.445625	No	No	0	0	0
1222	1x26	7x28	0.415625	No	Yes	0	3	2
1223	G.HN.46	G.HN.49	0.41	No	No	0	4	4
1224	G.s4h3.11	G.s4h3.12	0.40625	No	No	0	0	0
1225	b.h2x1	g.h3x5	0.396875	Yes	No	0	5	0
1226	G.H5.01	G.s6h5.04	0.3925	No	No	0	9	8
1227	b.1x21	b.b21x2	0.38125	No	Yes	0	3	6
1228	g.ntx1	g.ntx4	0.3725	No	No	0	4	4
1229	g.h3x3	g.l3x4	0.365	No	No	0	0	0
1230	G.hfs2.04	b.l7x5	0.363125	No	Yes	0	0	6
1231	g.h1x3	g.ntx4	0.36125	Yes	No	0	3	4
1232	g.ctx11	g.ctx17	0.345625	No	No	0	4	7
1233	G.H3.04	G.s4h3.08	0.331875	No	No	0	9	0
1234	G.s4h3.11	G.s4h3.13	0.325	No	No	0	0	0
1235	b.1x3	b.ntx3	0.318125	Yes	No	0	8	4
1236	b.lhb1x3	g.h3x9	0.313125	Yes	No	0	2	0
1237	b.l20x2	g.l2x4	0.31	Yes	No	0	9	0
1238	g.ntx1	g.ntx3	0.293125	No	No	0	4	4
1239	G.HN.36	b.b5x2	0.2925	No	Yes	0	4	7
1240	4x43	4x47	0.288125	No	No	0	4	3
1241	g.l1x2	g.l1x3	0.2625	No	No	0	2	1
1242	G.hns1.02	I2x58	0.259375	No	No	0	4	0
1243	b.l22x5	g.l3x1	0.246875	Yes	No	0	9	0
1244	g.l3x1	g.l3x2	0.231875	No	No	0	0	0
1245	8x55	8x59	0.224375	No	No	0	5	5
1246	G.HN.08	G.HN.11	0.21375	No	Yes	0	0	2
1247	4x48	4x51	0.21125	No	No	0	3	4
1248	g.l3x2	g.l3x3	0.204375	No	No	0	0	0
1249	g.h2x10	g.h2x13	0.18875	No	No	0	3	1
1250	6x27	6x30	0.175	No	No	0	3	7
1251	8x54	8x58	0.173125	No	No	0	5	6
1252	b.1x17	b.1x20	0.173125	No	No	0	4	3
1253	G.H4.10	G.hgh4.06	0.166875	Yes	No	0	6	3
1254	8x57	CT	0.155	No	No	0	5	0
1255	b.b1x4	g.ctx18	0.145625	Yes	No	0	7	0
1256	G.HN.09	G.HN.10	0.105625	No	No	0	5	4
1257	g.ntx4	g.ntx5	0.105	No	No	0	4	0
1258	g.ctx11	g.ctx14	0.0975	No	Yes	0	4	9
1259	g.h1x1	g.ntx6	0.096875	No	No	0	2	0
1260	g.h1x2	g.h1x3	0.095	No	Yes	0	2	3
1261	G.s4h3.09	G.s4h3.10	0.094375	No	No	0	0	0
1262	g.ntx1	g.ntx2	0.09125	No	No	0	4	3
1263	4x41	I2x59	0.073125	Yes	No	0	4	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.11	1.57175	5	0	2
2	G.HN.43	2.94562	4	3	9
3	G.S1.02	4.9935	5	4	5
4	G.S1.04	3.71734	4	4	7
5	G.S1.05	4.78125	4	1	9
6	G.S1.06	4.12859	4	4	8
7	G.S1.07	3.42675	5	1	9
8	G.H1.01	4.16563	5	4	9
9	G.H1.04	3.46788	5	4	7
10	G.S2.05	4.90047	4	0	3
11	G.S2.08	7.39094	4	4	5
12	G.S3.01	4.48887	5	4	4
13	G.S3.03	7.04896	6	4	7
14	G.S3.04	7.31453	4	1	6
15	G.S3.05	2.36719	4	0	7
16	G.S3.06	6.82313	6	1	5
17	G.S3.07	4.20078	4	4	9
18	G.s3h2.03	4.57487	5	1	9
19	G.H2.02	3.41078	4	1	8
20	G.H2.03	4.33266	4	1	9
21	G.H2.04	3.9825	5	1	9
22	G.H2.06	4.68359	8	1	9
23	G.H2.07	4.03117	8	1	9
24	G.H2.08	3.04588	5	1	8
25	G.H2.09	6.23484	4	1	8
26	G.h2s4.01	6.06337	5	1	9
27	G.S4.02	3.83825	5	1	8
28	G.S4.03	3.56531	4	4	7
29	G.S4.04	5.68638	5	1	9
30	G.S4.05	2.77078	4	4	7
31	G.S4.06	3.51656	4	0	7
32	G.s4h3.01	5.48547	4	1	7
33	G.s4h3.04	5.56555	8	1	8
34	G.H3.09	5.00911	7	1	9
35	G.H3.13	3.52109	4	1	5
36	G.H3.17	6.57677	6	1	5
37	G.H3.18	5.53828	4	1	9
38	G.S5.02	3.48078	4	1	6
39	G.S5.03	2.79063	5	4	8
40	G.S5.04	4.30075	5	1	9
41	G.S5.05	4.04352	8	4	9
42	G.S5.06	4.9505	5	1	8
43	G.HG.03	4.03594	4	1	6
44	G.HG.04	4.8465	5	1	9
45	G.HG.07	4.12516	4	1	9
46	G.HG.15	4.56938	4	0	7
47	G.hgh4.02	6.10036	7	7	7
48	G.hgh4.05	7.36125	4	7	7
49	G.H4.03	6.40413	5	0	4
50	G.H4.05	3.69703	4	7	4
51	G.H4.10	8.15963	5	7	6
52	G.H4.15	4.27838	5	1	8
53	G.h4s6.01	2.73734	4	0	4
54	G.h4s6.02	4.50078	4	1	8
55	G.h4s6.04	3.03641	4	0	4
56	G.h4s6.11	3.79844	4	1	7
57	G.S6.02	6.95625	4	0	7
58	G.S6.03	7.16641	4	1	5
59	G.S6.05	4.49781	4	1	4
60	G.s6h5.01	6.16469	4	4	9
61	G.H5.03	6.53891	4	4	8
62	G.H5.08	4.73448	6	4	8
63	G.H5.20	5.23312	4	0	9
64	G.H5.25	3.93887	5	2	7
65	G.H5.26	5.18775	5	10	5
66	b.1x3	0.981406	4	0	8
67	b.1x11	3.11516	4	0	6
68	b.lh12x2	4.38687	4	0	8
69	b.h2x1	3.11338	5	0	5
70	b.lhb1x3	2.8625	4	0	2
71	b.lhb1x6	4.19175	5	11	3
72	b.lhb1x9	2.41156	4	0	3
73	b.b1x4	3.57531	4	3	7
74	b.b1x6	6.14113	5	3	9
75	b.l1x3	7.34107	7	3	9
76	b.b2x1	7.90425	5	1	8
77	b.b2x3	3.81813	5	3	6
78	b.b2x5	6.14292	6	3	7
79	b.b3x2	5.31625	4	3	5
80	b.b3x3	3.56703	4	0	8
81	b.l3x2	4.68512	5	3	9
82	b.b4x2	4.53375	4	0	8
83	b.b4x3	3.39788	5	5	7
84	b.b4x5	4.25141	4	5	7
85	b.b4x6	8.85259	7	3	9
86	b.l4x2	10.3737	4	3	4
87	b.b5x2	4.95891	4	0	7
88	b.b5x3	5.80134	7	3	9
89	b.b5x5	5.00953	4	5	5
90	b.b5x7	4.81391	4	5	7
91	b.l5x1	4.01188	5	5	8
92	b.l5x5	6.34398	8	1	9
93	b.b6x5	3.7408	7	5	6
94	b.l6x5	6.32547	4	12	4
95	b.b7x1	5.71738	5	12	4
96	b.b7x4	3.14337	5	5	8
97	b.l7x2	3.20911	7	1	9
98	b.l7x4	3.64594	4	0	9
99	b.l7x5	3.01422	4	0	6
100	b.b8x3	3.42641	4	0	6
101	b.b8x4	4.88125	7	5	6
102	b.l8x1	3.57937	4	5	5
103	b.l8x5	2.98287	5	15	3
104	b.l8x8	4.20703	4	5	4
105	b.b9x3	5.35609	4	5	6
106	b.b9x4	5.34141	4	0	9
107	b.l9x3	5.76656	8	1	9
108	b.l9x6	4.24656	10	1	8
109	b.b10x5	4.32594	6	0	9
110	b.b11x4	4.73125	5	1	9
111	b.b11x6	7.81281	4	1	9
112	b.l11x2	8.89109	4	1	9
113	b.b12x2	4.2775	5	1	7
114	b.b12x3	3.22922	4	6	8
115	b.b12x6	7.63179	7	1	8
116	b.b12x7	5.97062	4	13	9
117	b.l12x3	4.22406	4	13	5
118	b.b13x3	6.94484	4	1	4
119	b.b13x7	7.4745	5	6	7
120	b.l13x3	7.14458	6	6	9
121	b.l13x6	4.42475	5	1	9
122	b.l13x7	3.66563	5	6	9
123	b.b14x3	4.41203	4	6	5
124	b.b14x5	3.49094	4	6	5
125	b.b15x1	5.77286	7	6	9
126	b.b15x2	5.41213	5	1	6
127	b.b15x3	4.62109	4	6	9
128	b.l15x1	4.79737	5	1	7
129	b.l15x2	5.08172	4	6	9
130	b.b16x4	10.2948	4	6	6
131	b.b16x5	3.92313	5	0	5
132	b.b16x6	8.5276	6	6	8
133	b.b17x5	5.78656	4	1	7
134	b.b17x7	8.60219	4	1	8
135	b.l17x3	7.72241	7	1	9
136	b.l17x6	6.51087	5	1	9
137	b.b18x3	5.06203	4	1	8
138	b.b18x5	4.82031	4	1	5
139	b.l18x1	5.46208	9	8	6
140	b.l18x2	6.42203	4	8	7
141	b.l18x3	5.60262	5	8	5
142	b.b19x2	6.0817	7	1	6
143	b.b19x4	4.85962	5	1	8
144	b.l19x1	6.46	4	1	9
145	b.l19x2	4.78162	5	1	9
146	b.b20x2	4.43712	5	1	6
147	b.b20x4	10.5787	5	1	8
148	b.b20x6	7.659	5	1	6
149	b.b20x7	3.63359	4	0	9
150	b.l20x2	4.39762	5	0	9
151	b.b21x1	6.17512	5	1	7
152	b.b21x2	2.06094	6	0	6
153	b.b21x5	5.12922	4	1	4
154	b.b21x6	4.04609	4	1	1
155	b.b21x7	4.64384	7	1	5
156	b.l21x5	3.555	5	1	4
157	b.b22x5	4.82237	5	8	7
158	b.l22x5	6.72938	6	11	9
159	b.b23x1	3.64172	4	0	5
160	b.b23x6	6.71929	7	1	7
161	b.l23x1	7.33063	4	1	6
162	b.b24x2	4.92656	4	1	5
163	b.b24x4	5.73396	6	1	6
164	b.b24x6	5.69359	4	1	8
165	b.l24x2	4.74891	4	0	6
166	b.l24x3	5.74062	4	0	5
167	b.b25x3	5.3025	5	1	5
168	b.l25x3	8.06287	5	9	9
169	b.l25x6	10.8314	4	1	8
170	b.b26x3	3.536	5	0	6
171	b.l28x1	11.6016	6	1	9
172	b.l28x2	6.64922	4	9	9
173	b.b28x3	3.55594	6	3	7
174	b.b28x4	6.91109	4	9	6
175	b.b28x6	9.20537	5	9	9
176	g.h1x3	1.40406	4	0	3
177	g.h1x10	4.35766	4	0	9
178	g.l1x4	3.39219	4	0	8
179	g.h2x11	8.08656	4	8	6
180	g.ctx3	6.19625	6	0	9
181	g.ctx6	4.10073	6	11	6
182	g.ctx14	4.1215	5	3	9
183	g.ctx15	5.84406	4	3	9
184	g.ctx16	4.02604	9	3	8
185	Lig	24.9304	25	2	0
186	NT	8.98675	5	2	5
187	1x39	5.97813	4	0	7
188	1x59	2.25927	6	0	4
189	2x38	3.74109	4	2	7
190	2x40	3.27312	4	0	8
191	2x42	5.24937	6	2	7
192	2x46	3.69141	4	2	9
193	2x50	6.363	5	2	9
194	2x53	5.19075	5	2	6
195	2x57	3.33775	5	2	7
196	2x63	5.78266	4	2	5
197	E1x50	7.52312	6	2	8
198	E1x52	6.80275	5	2	7
199	3x25	4.85375	4	2	9
200	3x30	5.17469	4	17	5
201	3x32	4.74172	4	2	6
202	3x33	3.17802	6	2	4
203	3x37	3.93302	6	2	7
204	3x42	4.50275	5	2	7
205	3x49	5.57453	4	2	8
206	3x50	5.92387	5	2	9
207	3x51	4.55	5	14	8
208	3x55	4.40641	4	14	8
209	4x41	1.79516	4	0	4
210	4x50	5.20388	5	2	9
211	4x64	6.21563	4	2	5
212	4x65	6.557	5	2	4
213	E2	11.155	17	2	3
214	5x35	4.55562	5	2	1
215	5x36	5.633	5	2	4
216	5x47	4.08135	6	2	8
217	5x50	3.48563	4	2	9
218	5x54	3.49406	4	2	8
219	5x58	5.25839	7	2	9
220	5x62	2.60844	4	0	5
221	5x65	3.45563	4	10	7
222	I3	3.752	5	10	4
223	6x44	4.68354	6	2	9
224	6x45	3.86328	4	2	6
225	6x48	6.00982	7	2	9
226	6x49	4.34406	4	2	6
227	6x51	6.02969	4	2	6
228	6x59	5.29609	4	2	5
229	E3	3.62979	6	2	1
230	7x28	1.52516	4	2	2
231	7x30	2.45552	6	2	4
232	7x42	4.62313	5	2	6
233	7x49	3.77896	6	2	9
234	7x50	3.84953	4	0	9
235	7x53	4.53304	7	2	9
236	7x55	5.33359	4	0	7
237	8x50	6.07578	4	0	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b4x1	b.l5x1	15.1406	3.95438	No	Yes	0	8	8
2	b.b4x1	b.l5x4	15.1813	2.78437	No	No	0	8	8
3	b.l5x4	b.l5x5	15.2247	2.23875	No	Yes	0	8	9
4	G.h2s4.01	b.l5x5	14.8871	10.2125	Yes	Yes	1	9	9
5	G.S1.05	G.h2s4.01	53.4065	9.44125	Yes	Yes	1	9	9
6	G.S1.05	G.S1.07	52.681	4.58687	Yes	Yes	1	9	9
7	G.S1.07	G.s1h1.01	100	1.60313	Yes	No	0	9	9
8	G.H1.01	G.s1h1.01	99.9921	3.7025	Yes	No	0	9	9
9	G.H1.01	G.S1.06	50.8106	4.5825	Yes	Yes	4	9	8
10	G.S1.06	G.S4.03	49.482	3.02938	Yes	Yes	4	8	7
11	G.S1.07	G.S4.04	10.9957	3.27625	Yes	Yes	1	9	9
12	G.H3.12	G.S1.07	25.5593	5.08313	No	Yes	1	8	9
13	G.H2.04	G.H3.12	25.5028	4.38375	Yes	No	1	9	8
14	G.H2.04	G.H2.07	21.164	3.875	Yes	Yes	1	9	9
15	G.H2.07	G.h2s4.01	19.0919	4.135	Yes	Yes	1	9	9
16	G.H2.07	b.l9x6	40.9911	2.47187	Yes	Yes	1	9	8
17	b.b10x1	b.l9x6	10.3809	3.34	No	Yes	0	9	8
18	b.b10x1	b.b11x5	10.2698	2.75062	No	No	0	9	6
19	G.H1.01	G.S4.05	48.9628	3.02938	Yes	Yes	4	9	7
20	G.S4.05	G.S5.05	48.5848	2.44313	Yes	Yes	4	7	9
21	G.H2.06	b.l9x6	46.428	3.20687	Yes	Yes	1	9	8
22	G.H2.06	b.l17x6	22.9526	8.12625	Yes	Yes	1	9	9
23	G.H2.06	b.l19x1	22.9306	3.37188	Yes	Yes	1	9	9
24	G.H2.08	G.H3.17	15.6685	2.20312	Yes	Yes	1	8	5
25	G.H3.18	G.S4.02	13.8534	7.85125	Yes	Yes	1	9	8
26	G.S4.03	G.S5.03	48.3965	2.57375	Yes	Yes	4	7	8
27	G.S5.03	G.S5.05	48.4279	2.9825	Yes	Yes	4	8	9
28	G.H5.10	G.S5.03	96.6394	3.655	No	Yes	0	6	8
29	G.H5.10	G.S6.02	96.5723	6.25375	No	Yes	0	6	7
30	G.S6.02	G.h4s6.12	48.5054	11.8538	Yes	No	0	7	4
31	G.H5.13	G.S6.02	48.4222	5.82	No	Yes	0	8	7
32	G.h4s6.12	I3	48.3458	2.55375	No	Yes	10	4	4
33	G.H5.13	I3	48.347	3.26313	No	Yes	0	8	4
34	G.H5.20	G.H5.26	39.8354	12.5588	Yes	Yes	0	9	5
35	5x65	G.H5.26	40.2851	2.81625	Yes	Yes	10	7	5
36	5x65	I3	94.2159	4.01	Yes	Yes	10	7	4
37	G.H5.20	G.H5.25	39.0244	3.11438	Yes	Yes	0	9	7
38	3x50	G.H5.25	37.4218	7.43812	Yes	Yes	2	9	7
39	5x62	6x37	52.9812	4.14563	Yes	No	0	5	7
40	5x62	6x34	53.4506	4.0775	Yes	No	0	5	7
41	5x65	6x34	53.6072	4.46875	Yes	No	0	7	7
42	b.l17x5	b.l17x6	23.0188	4.51	No	Yes	1	6	9
43	b.l17x5	b.l19x2	45.6412	2.85188	No	Yes	1	6	9
44	b.l17x3	b.l19x2	36.5523	3.465	Yes	Yes	1	9	9
45	b.b19x4	b.l17x3	28.1429	7.86937	Yes	Yes	1	8	9
46	b.l17x5	b.l19x1	22.8456	4.87625	No	Yes	1	6	9
47	b.b19x2	b.b19x4	15.431	2.42812	Yes	Yes	1	6	8
48	b.b17x7	b.b20x6	20.5106	9.91438	Yes	Yes	1	8	6
49	b.b20x4	b.b20x6	14.1267	4.27687	Yes	Yes	1	8	6
50	b.b17x7	b.b21x1	24.8165	4.85312	Yes	Yes	1	8	7
51	b.1x19	b.b21x1	18.6723	8.26312	No	Yes	0	2	7
52	b.1x19	b.b21x2	16.8624	3.7225	No	Yes	0	2	6
53	b.b22x2	b.b26x3	10.6735	5.62813	No	Yes	0	8	6
54	b.b22x1	b.b22x2	10.7863	3.2	No	No	0	8	8
55	b.l23x1	b.l25x6	10.0619	18.1656	Yes	Yes	1	6	8
56	3x32	Lig	26.0922	5.30812	Yes	Yes	2	6	0
57	2x53	3x32	13.7521	8.30062	Yes	Yes	2	6	6
58	2x53	7x46	17.9494	4.53062	Yes	No	0	6	9
59	2x50	7x46	18.2815	5.90812	Yes	No	0	9	9
60	2x50	7x49	18.8829	6.395	Yes	Yes	2	9	9
61	7x49	7x53	24.2218	3.92625	Yes	Yes	2	9	9
62	3x50	7x53	30.2434	5.5925	Yes	Yes	2	9	9
63	3x32	3x33	13.7098	3.09625	Yes	Yes	2	6	4
64	3x33	3x36	31.4733	2.26125	Yes	No	2	4	7
65	3x36	6x48	45.7251	6.0825	No	Yes	2	7	9
66	6x44	6x48	46.4684	11.0112	Yes	Yes	2	9	9
67	5x54	6x44	51.2957	3.7375	Yes	Yes	2	8	9
68	5x54	5x58	51.3955	3.24437	Yes	Yes	2	8	9
69	5x58	6x37	52.8269	8.54938	Yes	No	0	9	7
70	5x43	Lig	25.9192	2.32687	No	Yes	2	4	0
71	3x33	5x43	13.1246	3.715	Yes	No	2	4	4
72	3x37	5x43	13.1067	3.8525	Yes	No	2	7	4
73	3x36	3x37	14.1128	6.38937	No	Yes	2	7	7
74	E2	Lig	19.5117	29.2163	Yes	Yes	2	3	0
75	E1x50	E1x52	10.0699	16.9112	Yes	Yes	2	8	7
76	b.1x2	b.b21x2	12.5162	0.803125	No	Yes	0	1	6
77	b.1x2	b.1x3	10.3383	1.09625	No	Yes	0	1	8
78	b.l7x2	b.l9x6	19.9118	2.855	Yes	Yes	1	9	8
79	b.b22x1	b.l25x6	10.8704	2.67	No	Yes	1	8	8
80	G.h2s4.01	b.l7x2	18.9755	2.44	Yes	Yes	1	9	9
81	G.H3.17	b.l25x6	21.3439	3.4375	Yes	Yes	1	5	8
82	G.S1.07	G.S4.02	13.7854	2.58437	Yes	Yes	1	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x60	Lig	12.4494	2	No	Yes	6	0	1	0
3x32	Lig	5.30812	2	Yes	Yes	6	0	1	0
7x38	Lig	6.69313	2	No	Yes	5	0	1	0
6x58	Lig	4.8025	2	No	Yes	3	0	1	0
7x31	Lig	5.73625	0	No	Yes	3	0	1	0
7x34	Lig	5.46688	2	No	Yes	4	0	1	0
1x28	Lig	3.08375	0	No	Yes	2	0	1	0
2x63	Lig	2.55125	2	Yes	Yes	5	0	1	0
E2	Lig	29.2163	2	Yes	Yes	3	0	1	0
7x35	Lig	2.76188	2	No	Yes	3	0	1	0
Lig	NT	26.2206	2	Yes	Yes	0	5	0	1
E2x51	Lig	16.6906	2	No	Yes	4	0	1	0
5x32	Lig	3.88437	2	No	Yes	2	0	1	0
6x61	Lig	5.91438	2	No	Yes	2	0	1	0
NT	NT	7.09688	2	Yes	Yes	5	5	1	1
7x24	NT	2.73	0	No	Yes	8	5	2	1
1x35	7x35	2.58562	0	No	No	5	3	2	1
2x53	3x32	8.30062	2	Yes	Yes	6	6	2	1
2x53	7x42	5.35312	2	Yes	Yes	6	6	2	2
2x56	3x32	2.26188	0	No	Yes	6	6	2	1
2x60	2x63	4.59188	2	No	Yes	6	5	1	1
2x63	E1x50	9.54062	2	Yes	Yes	5	8	1	2
2x67	E2	5.07625	2	No	Yes	3	3	2	1
E1x49	E2	9.65375	2	No	Yes	4	3	2	1
3x25	E1x50	6.69563	2	Yes	Yes	9	8	2	2
E1x50	E2	3.06063	2	Yes	Yes	8	3	2	1
3x22	E2	7.92437	2	No	Yes	3	3	2	1
3x25	4x65	2.21187	2	Yes	Yes	9	4	2	2
3x25	E2	3.34125	2	Yes	Yes	9	3	2	1
3x32	3x33	3.09625	2	Yes	Yes	6	4	1	2
3x37	5x43	3.8525	2	Yes	No	7	4	2	1
4x64	E2	13.6325	2	Yes	Yes	5	3	2	1
4x64	5x35	5.29562	2	Yes	Yes	5	1	2	2
4x65	E2x52	6.69875	2	Yes	No	4	4	2	1
E2	E2	37.1281	2	Yes	Yes	3	3	1	1
E2	E2x51	8.38313	2	Yes	No	3	4	1	1
E2	E2x52	3.06437	2	Yes	No	3	4	1	1
5x32	E2	4.51875	2	No	Yes	2	3	1	1
5x35	E2	7.8675	2	Yes	Yes	1	3	2	1
5x39	E2	3.12312	0	No	Yes	5	3	2	1
5x31	E2	4.39563	2	No	Yes	5	3	2	1
5x31	5x35	4.66625	2	No	Yes	5	1	2	2
5x36	6x59	4.70062	2	Yes	Yes	4	5	1	2
5x40	6x55	2.7025	2	No	No	5	5	2	2
5x40	6x59	4.78125	2	No	Yes	5	5	2	2
6x51	6x55	10.5188	2	Yes	No	6	5	1	2
6x51	7x37	3.2175	2	Yes	No	6	7	1	2
6x51	7x38	4.69875	2	Yes	No	6	5	1	1
6x54	7x34	4.4625	0	No	No	4	4	2	1
6x54	7x37	2.57	0	No	No	4	7	2	2
6x57	7x30	3.56625	2	No	Yes	5	4	2	1
6x58	7x30	3.2425	2	No	Yes	3	4	1	1
6x61	7x30	2.39563	2	No	Yes	2	4	1	1
E3	E3	2.81375	2	Yes	Yes	1	1	2	2
7x38	7x42	3.09562	2	No	Yes	5	6	1	2
3x33	3x37	2.89188	2	Yes	Yes	4	7	2	2
3x33	5x43	3.715	2	Yes	No	4	4	2	1
E2x52	Lig	7.56625	2	No	Yes	4	0	1	0
5x36	E2	9.91125	2	Yes	Yes	4	3	1	1
5x32	5x35	3.01	2	No	Yes	2	1	1	2
5x36	Lig	4.78938	2	Yes	Yes	4	0	1	0
6x61	E3	4.04437	2	No	Yes	2	1	1	2
7x27	Lig	5.34625	0	No	Yes	3	0	1	0
6x51	Lig	5.68375	2	Yes	Yes	6	0	1	0
6x57	E3	3.3025	2	No	Yes	5	1	2	2
5x43	Lig	2.32687	2	No	Yes	4	0	1	0
5x36	6x58	4.24563	2	Yes	No	4	3	1	1
2x63	E1	6.44688	2	Yes	No	5	0	1	1
E1	Lig	6.27437	2	No	Yes	0	0	1	0
5x36	5x40	4.51813	2	Yes	No	4	5	1	2
2x64	E1	2.67	0	No	No	4	0	2	1
5x29	E2	2.21	2	No	Yes	0	3	2	1
7x30	Lig	3.61	2	Yes	Yes	4	0	1	0
6x62	Lig	1.92375	0	No	Yes	3	0	1	0
7x28	NT	1.78938	2	Yes	Yes	2	5	2	1
7x29	7x30	1.31	0	No	Yes	3	4	2	1
1x25	Lig	1.005	0	No	Yes	1	0	1	0
6x65	7x30	0.60875	0	No	Yes	1	4	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
64.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
64.00	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
64.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
62.50	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
62.07	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
62.07	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
62.07	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
61.54	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
61.54	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
60.87	Single	6OS2	TRV026	6OS2-AT₁-TRV026
60.71	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
60.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
59.26	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
59.26	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
59.26	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
58.62	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
58.06	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
57.14	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
56.52	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
56.52	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
54.84	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
53.85	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
53.57	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
53.12	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
51.85	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
51.72	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
51.72	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
51.61	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
51.52	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
50.00	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
50.00	Single	6OS1	TRV026	6OS1-AT₁-TRV026
50.00	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
50.00	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
50.00	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
50.00	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
50.00	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
50.00	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
50.00	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
50.00	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
50.00	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.39	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
48.39	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
48.39	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
48.28	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
48.28	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
48.28	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
48.28	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
48.00	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
48.00	Consensus	dp_off	Orthosteric Ligand	dp2_off
47.06	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
46.88	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
46.88	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
46.88	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
46.88	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
46.67	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
46.67	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
46.67	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
46.67	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.67	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
46.43	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
46.15	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
45.16	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
45.16	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
44.83	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
44.44	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
44.44	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.44	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
44.44	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
44.44	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
44.44	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
44.12	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
44.00	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
43.75	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
43.48	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
43.33	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
42.86	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
42.86	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
42.86	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
42.86	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
42.31	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
42.31	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
41.94	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
41.94	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
41.94	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.94	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
41.94	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.94	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
41.67	Single	6D27	CAY10471	6D27-DP₂-CAY10471
41.67	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
41.67	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
41.67	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
41.67	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
41.67	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
41.38	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
41.38	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
41.38	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
41.38	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.74	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
40.74	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
40.74	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
40.00	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
40.00	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
40.00	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
40.00	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
40.00	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
40.00	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
40.00	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
40.00	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
39.29	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
39.29	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
39.13	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
39.13	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
38.71	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
38.71	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
38.46	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
38.46	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
38.46	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
38.46	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
38.24	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
37.93	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
37.93	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
37.93	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
37.93	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
37.93	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
37.93	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
37.50	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
37.04	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
37.04	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
37.04	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
37.04	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
37.04	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
37.04	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
37.04	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
37.04	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
37.04	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
37.04	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
36.67	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
36.67	Consensus	sst_off	Orthosteric Ligand	sst2_off
36.67	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
36.36	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
36.36	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
36.36	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
36.00	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
35.71	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
35.71	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
35.71	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
35.71	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
35.71	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.71	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.71	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
35.48	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
35.48	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
35.48	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
35.29	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
34.78	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
34.62	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
34.48	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
34.48	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
34.48	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
34.48	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
34.48	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
34.48	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
34.48	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.38	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
34.38	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
34.38	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
34.38	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
34.38	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
34.38	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
34.38	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
34.29	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
33.33	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
33.33	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
33.33	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
33.33	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
33.33	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
33.33	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
33.33	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
33.33	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
33.33	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
33.33	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
33.33	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
33.33	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
33.33	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
33.33	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
33.33	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
33.33	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
33.33	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
32.35	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
32.35	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.35	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.35	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
32.35	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
32.35	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
32.26	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
32.26	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
32.26	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
32.26	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
32.26	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
32.26	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
32.14	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
32.14	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
32.14	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
32.14	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
32.14	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
32.14	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
32.14	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.14	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
32.14	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
32.14	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
32.14	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
32.14	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.14	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
32.14	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
32.14	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
32.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
32.00	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
32.00	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
32.00	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
32.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
32.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
32.00	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
32.00	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
31.43	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
31.43	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
31.25	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
31.25	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
31.25	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
31.03	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
31.03	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
31.03	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
31.03	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
31.03	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
31.03	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
31.03	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
31.03	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
31.03	Consensus	orexin_on	Orthosteric Ligand	ox2_on
31.03	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
30.77	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
30.77	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
30.77	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
30.77	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
30.56	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
30.56	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
30.30	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
30.30	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.00	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
30.00	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
30.00	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
30.00	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
30.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
30.00	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
30.00	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
30.00	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
30.00	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
29.63	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
29.63	Single	5N2S	PSB36	5N2S-A₁-PSB36
29.63	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
29.63	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
29.63	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.63	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.63	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
29.63	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
29.63	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
29.63	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
29.63	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.63	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
29.41	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
29.17	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
29.17	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
29.17	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
29.03	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
29.03	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
29.03	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
29.03	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
29.03	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
29.03	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
28.95	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
28.95	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
28.57	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
28.57	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
28.57	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
28.57	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
28.57	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
28.57	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
28.57	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
28.57	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
28.57	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
28.57	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
28.57	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
28.57	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.57	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
28.57	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
28.57	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
28.57	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
28.57	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
28.57	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
28.57	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
28.57	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
28.57	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
28.12	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
28.12	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
28.12	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
28.12	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
28.12	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
28.00	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
28.00	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
28.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
27.59	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
27.59	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
27.59	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
27.59	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.59	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.59	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
27.59	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
27.59	Consensus	nts_off	Orthosteric Ligand	nts1_off
27.50	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
27.27	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
27.27	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
27.27	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
27.27	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
27.27	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
27.03	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
27.03	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
26.92	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
26.92	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
26.92	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
26.92	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
26.92	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
26.92	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
26.92	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
26.92	Consensus	hcar_on	Orthosteric Ligand	hca_on
26.83	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
26.67	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
26.67	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
26.67	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
26.67	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
26.67	Single	7EZC	UKA	7EZC-A_2A-UKA
26.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
26.67	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
26.67	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
26.67	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
26.67	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
26.67	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
26.47	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
26.47	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
26.47	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.47	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
26.47	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
26.47	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
26.47	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
26.32	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
26.32	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
26.32	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
25.93	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
25.93	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
25.93	Single	5UEN	DU172	5UEN-A₁-DU172
25.93	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
25.93	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
25.93	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
25.93	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
25.93	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
25.93	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
25.93	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
25.93	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
25.93	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
25.93	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
25.93	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
25.93	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
25.93	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
25.93	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
25.93	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
25.93	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
25.93	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
25.93	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
25.93	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
25.93	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
25.81	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
25.81	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
25.81	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
25.81	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.81	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
25.81	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
25.81	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
25.81	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
25.81	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
25.81	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
25.81	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
25.81	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
25.71	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
25.71	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
25.71	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
25.71	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
25.71	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
25.71	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.64	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
25.64	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
25.58	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
25.00	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
25.00	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
25.00	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
25.00	Single	5C1M	BU72	5C1M-μ-BU72
25.00	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
25.00	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
25.00	Single	6FJ3	PTH	6FJ3-PTH1-PTH
25.00	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
25.00	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
25.00	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
25.00	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
25.00	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
25.00	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
25.00	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
25.00	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
25.00	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
25.00	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
25.00	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
25.00	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
25.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
25.00	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
25.00	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
25.00	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
25.00	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
25.00	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
25.00	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
25.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
25.00	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
25.00	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
25.00	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
25.00	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
25.00	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
25.00	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
24.39	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
24.32	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
24.32	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
24.32	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
24.32	Consensus	go_class-b1	Orthosteric Ligand	go_crf
24.32	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
24.24	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
24.24	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
24.24	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Single	3P0G	BI167107	3P0G-β₂-BI167107
24.14	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
24.14	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
24.14	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
24.14	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
24.14	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
24.14	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
24.14	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
24.14	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
24.14	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
24.14	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
24.14	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
24.14	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
24.14	Single	8E0G	BU72	8E0G-μ-BU72
24.14	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
24.14	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
24.14	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
24.14	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
24.14	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
24.14	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
24.14	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
24.14	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
24.00	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
24.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
24.00	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
24.00	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
24.00	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
24.00	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
24.00	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
23.91	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
23.68	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
23.68	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
23.53	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
23.53	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
23.53	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
23.33	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
23.33	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
23.33	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
23.33	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
23.33	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
23.33	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.33	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
23.33	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
23.33	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
23.33	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
23.33	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
23.33	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.33	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
23.33	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
23.33	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
23.33	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
23.33	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.33	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
23.33	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
23.33	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
23.33	Consensus	blt_off	Orthosteric Ligand	blt1_off
23.33	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
23.33	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
23.33	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
23.33	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
23.33	Consensus	nts_on	Orthosteric Ligand	nts1_on
23.33	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
23.08	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
23.08	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
23.08	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
23.08	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
23.08	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
23.08	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
23.08	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
23.08	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
23.08	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
23.08	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
23.08	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
23.08	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
23.08	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
23.08	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
23.08	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
23.08	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
23.08	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
23.08	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
23.08	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
23.08	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
22.86	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
22.86	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
22.86	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
22.86	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
22.73	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
22.58	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
22.58	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
22.58	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
22.58	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
22.58	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
22.58	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
22.58	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
22.58	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
22.58	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
22.58	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
22.58	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
22.58	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
22.58	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
22.58	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
22.58	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
22.50	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
22.22	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
22.22	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
22.22	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
22.22	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
22.22	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
22.22	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
22.22	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
22.22	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
22.22	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
22.22	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
22.22	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
22.22	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
22.22	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
22.22	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
22.22	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	7T32	ZM241385	7T32-A_2A-ZM241385
22.22	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
22.22	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
22.22	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
22.22	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
22.22	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
22.22	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
22.22	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
22.22	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
22.22	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
22.22	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
22.22	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
22.22	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
22.22	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
22.22	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
21.95	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
21.88	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
21.88	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
21.88	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.88	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
21.88	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
21.88	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
21.88	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.88	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
21.88	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
21.88	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.74	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
21.74	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
21.62	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
21.62	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
21.43	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
21.43	Single	3EML	ZM241385	3EML-A_2A-ZM241385
21.43	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
21.43	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
21.43	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
21.43	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
21.43	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
21.43	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
21.43	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
21.43	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
21.43	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
21.43	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
21.43	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
21.43	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
21.43	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
21.43	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
21.43	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
21.43	Single	7BU7	BI167107	7BU7-β₁-BI167107
21.43	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
21.43	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
21.43	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
21.43	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
21.43	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
21.43	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
21.43	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
21.43	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
21.43	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
21.43	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
21.43	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
21.43	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
21.43	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
21.43	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
21.43	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
21.43	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
21.43	Consensus	a2_off	Orthosteric Ligand	a2a_off
21.43	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
21.43	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
21.43	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
21.43	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
21.43	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
21.43	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
21.43	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
21.43	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
21.43	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
21.43	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
21.43	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
21.28	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
21.21	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
21.21	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
21.21	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
21.21	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
21.05	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
21.05	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
21.05	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
21.05	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
21.05	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
20.93	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
20.93	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
20.93	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
20.83	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
20.69	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
20.69	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
20.69	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
20.69	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
20.69	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
20.69	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
20.69	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
20.69	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
20.69	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
20.69	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
20.69	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
20.69	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
20.69	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
20.69	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
20.69	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
20.69	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
20.69	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
20.69	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
20.69	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
20.69	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
20.69	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
20.69	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
20.69	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
20.69	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
20.69	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
20.69	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
20.69	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
20.69	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
20.69	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
20.69	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
20.69	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
20.69	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
20.69	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
20.69	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
20.59	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
20.59	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
20.59	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
20.59	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
20.59	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
20.59	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
20.59	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
20.51	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
20.51	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
20.51	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
20.51	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
20.51	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
20.00	Single	2YDV	NECA	2YDV-A_2A-NECA
20.00	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
20.00	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
20.00	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
20.00	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
20.00	Single	5G53	NECA	5G53-A_2A-NECA-Gs
20.00	Single	5V56	TC114	5V56-SMO-TC114
20.00	Single	5V57	TC114	5V57-SMO-TC114
20.00	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
20.00	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
20.00	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
20.00	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
20.00	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
20.00	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
20.00	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
20.00	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
20.00	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
20.00	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
20.00	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
20.00	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
20.00	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
20.00	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
20.00	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
20.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
20.00	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
20.00	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
20.00	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
20.00	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
20.00	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
20.00	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
20.00	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
20.00	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
20.00	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
20.00	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
20.00	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
20.00	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
20.00	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
20.00	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
20.00	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
20.00	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
20.00	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
20.00	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
20.00	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
20.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
19.51	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
19.51	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
19.44	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
19.35	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
19.35	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
19.35	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
19.35	Single	4LDE	BI167107	4LDE-β₂-BI167107
19.35	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
19.35	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
19.35	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
19.35	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
19.35	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
19.35	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
19.35	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
19.35	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
19.35	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
19.35	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
19.35	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
19.35	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
19.35	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
19.35	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
19.35	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
19.35	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
19.35	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
19.35	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
19.35	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
19.35	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
19.35	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
19.35	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
19.35	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
19.35	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
19.35	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
19.35	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
19.35	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
19.35	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
19.35	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
19.35	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
19.35	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
19.23	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
19.23	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
19.23	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
19.23	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
19.23	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
19.23	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
19.23	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
19.23	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
19.23	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
19.23	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
19.23	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
19.23	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
19.23	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
19.23	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
19.23	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
19.23	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
19.23	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
19.23	Consensus	go_protein	Orthosteric Ligand	go_chemokine
19.23	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
19.05	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
19.05	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
18.92	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
18.92	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
18.92	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
18.92	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
18.92	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
18.75	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
18.75	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
18.75	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
18.75	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
18.75	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
18.75	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
18.75	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
18.75	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
18.75	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
18.75	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
18.75	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.75	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
18.75	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
18.75	Consensus	endothelin_off	Orthosteric Ligand	etb_off
18.75	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
18.75	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.75	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
18.60	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
18.60	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
18.52	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
18.52	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
18.52	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
18.52	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
18.52	Single	5WS3	EMPA	5WS3-OX₂-EMPA
18.52	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
18.52	Single	6AKX	A4R	6AKX-CCR5-A4R
18.52	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
18.52	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
18.52	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
18.52	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
18.52	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
18.52	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
18.52	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
18.52	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
18.52	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
18.52	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
18.52	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
18.52	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
18.52	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
18.52	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
18.52	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
18.52	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
18.52	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
18.52	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
18.52	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
18.52	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
18.52	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
18.52	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
18.52	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
18.52	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
18.52	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
18.52	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
18.52	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
18.52	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
18.52	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
18.52	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
18.52	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
18.52	Consensus	class-f_off	Orthosteric Ligand	smo_off
18.52	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
18.52	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
18.52	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
18.52	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
18.52	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
18.52	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
18.42	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
18.42	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
18.42	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
18.42	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
18.42	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
18.18	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
18.18	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
18.18	Single	6PT3	DPI-287	6PT3-δ-DPI-287
18.18	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
18.18	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
18.18	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
18.18	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
18.18	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
18.18	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.95	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
17.95	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
17.95	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
17.86	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
17.86	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
17.86	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
17.86	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
17.86	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
17.86	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
17.86	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
17.86	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
17.86	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
17.86	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
17.86	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
17.86	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
17.86	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
17.86	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
17.86	Single	6TPG	EMPA	6TPG-OX₂-EMPA
17.86	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
17.86	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
17.86	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
17.86	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
17.86	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
17.86	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.86	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
17.86	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
17.86	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
17.86	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
17.86	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.86	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
17.86	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
17.86	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
17.86	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
17.86	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
17.86	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
17.86	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
17.86	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.86	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.86	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.86	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
17.86	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
17.86	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
17.86	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
17.86	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
17.86	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
17.86	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.86	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
17.86	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.86	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.86	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.86	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.86	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
17.86	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
17.86	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
17.86	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
17.86	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
17.86	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
17.86	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
17.86	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
17.86	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
17.86	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
17.86	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
17.86	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
17.65	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
17.65	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
17.65	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
17.65	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
17.65	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
17.50	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
17.50	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
17.50	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
17.50	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
17.50	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
17.24	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
17.24	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
17.24	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
17.24	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
17.24	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
17.24	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
17.24	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
17.24	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
17.24	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
17.24	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
17.24	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
17.24	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
17.24	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
17.24	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
17.24	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
17.24	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
17.24	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
17.24	Single	6PS1	Timolol	6PS1-β₂-Timolol
17.24	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
17.24	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
17.24	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
17.24	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
17.24	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
17.24	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
17.24	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
17.24	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
17.24	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
17.24	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
17.24	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
17.24	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
17.24	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
17.24	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
17.24	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
17.24	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
17.24	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
17.24	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
17.24	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
17.24	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
17.24	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
17.24	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
17.24	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
17.24	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.24	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
17.24	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
17.24	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
17.24	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
17.24	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
17.24	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
17.24	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
17.24	Consensus	cck_off	Orthosteric Ligand	ccka_off
17.24	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
17.24	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
17.24	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
17.24	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
17.24	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
17.24	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
17.24	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
17.24	Consensus	tar_on	Orthosteric Ligand	ta1_on
17.14	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
17.14	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
17.07	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
17.07	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
17.07	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
17.02	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
16.67	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
16.67	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
16.67	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
16.67	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
16.67	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
16.67	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
16.67	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
16.67	Single	5WQC	EMPA	5WQC-OX₂-EMPA
16.67	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
16.67	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
16.67	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
16.67	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
16.67	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
16.67	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
16.67	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
16.67	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
16.67	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
16.67	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
16.67	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
16.67	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
16.67	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
16.67	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
16.67	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
16.67	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
16.67	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
16.67	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
16.67	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
16.67	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
16.67	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
16.67	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
16.67	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
16.67	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
16.67	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
16.67	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
16.67	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
16.67	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
16.67	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
16.67	Consensus	ep_off	Orthosteric Ligand	ep4_off
16.67	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
16.28	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
16.22	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
16.13	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
16.13	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
16.13	Single	5X93	K-8794	5X93-ET_B-K-8794
16.13	Single	5XR8	AM841	5XR8-CB₁-AM841
16.13	Single	5XRA	AM11542	5XRA-CB₁-AM11542
16.13	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
16.13	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
16.13	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
16.13	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
16.13	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
16.13	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
16.13	Single	7W41	PD176252	7W41-BB₂-PD176252
16.13	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
16.13	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
16.13	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
16.13	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
16.13	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.13	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
16.13	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
16.13	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
16.13	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
16.13	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
16.13	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
16.13	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
16.13	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
16.13	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
16.13	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
16.13	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
16.13	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
16.13	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
16.13	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
16.13	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
16.13	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
16.13	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
16.13	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
16.00	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
16.00	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
16.00	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
16.00	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
16.00	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
16.00	Consensus	sensory_on	Orthosteric Ligand	opsin_on
15.79	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
15.79	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
15.79	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
15.62	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
15.62	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
15.62	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
15.62	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
15.62	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
15.62	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
15.62	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
15.62	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
15.62	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
15.62	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
15.62	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
15.62	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
15.62	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
15.62	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
15.62	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
15.62	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
15.62	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.62	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
15.62	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
15.62	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
15.62	Consensus	gi_class-f	Other Ligand	gi_frizzled
15.62	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
15.62	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
15.38	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
15.38	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
15.38	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
15.38	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
15.38	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
15.38	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
15.38	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
15.38	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
15.38	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
15.38	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
15.38	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
15.38	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
15.38	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
15.38	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
15.15	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
15.15	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
15.15	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
15.15	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.15	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
15.15	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
15.15	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
15.15	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
15.15	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
15.15	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
15.15	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
15.15	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
15.15	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
15.15	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.15	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.15	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.00	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
15.00	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
14.81	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
14.81	Single	6HLL	CP99994	6HLL-NK₁-CP99994
14.81	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
14.81	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
14.81	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
14.81	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
14.81	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
14.81	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
14.81	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
14.81	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
14.81	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
14.81	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
14.81	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
14.81	Consensus	class-t_on	Orthosteric Ligand	taste2_on
14.81	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
14.81	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
14.81	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
14.81	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
14.81	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
14.81	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
14.81	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
14.71	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
14.71	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.71	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
14.71	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
14.63	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
14.63	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
14.29	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
14.29	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
14.29	Single	5U09	Taranabant	5U09-CB₁-Taranabant
14.29	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
14.29	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
14.29	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
14.29	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
14.29	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
14.29	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
14.29	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
14.29	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
14.29	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
14.29	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
14.29	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
14.29	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
14.29	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
14.29	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
14.29	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
14.29	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
14.29	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
14.29	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
14.29	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
14.29	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
14.29	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
14.29	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
14.29	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
14.29	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
13.89	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
13.89	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.89	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
13.79	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
13.79	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
13.79	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
13.79	Single	6IQL	L745870	6IQL-D₄-L745870
13.79	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
13.79	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
13.79	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
13.79	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
13.79	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
13.79	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
13.79	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
13.79	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
13.79	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
13.79	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
13.79	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.79	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
13.79	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
13.79	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.79	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
13.79	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
13.79	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
13.79	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
13.79	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
13.79	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
13.79	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
13.79	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.79	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.79	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
13.79	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
13.79	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
13.79	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
13.79	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
13.79	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
13.79	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
13.79	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
13.64	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
13.51	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
13.51	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
13.33	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
13.33	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
13.33	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
13.33	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
13.33	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
13.33	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
13.33	Single	6GPS	MK0812	6GPS-CCR2-MK0812
13.33	Single	6IIV	Daltroban	6IIV-TP-Daltroban
13.33	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
13.33	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
13.33	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
13.33	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
13.33	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
13.33	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
13.33	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
13.33	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
13.33	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
13.33	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
13.33	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
13.33	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
13.33	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
13.33	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
13.33	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
13.33	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
13.33	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
13.33	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
13.33	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
13.33	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
13.33	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
13.33	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
13.33	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
13.33	Consensus	blt_on	Orthosteric Ligand	blt1_on
13.33	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
13.33	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
13.33	Consensus	leuko_on	Orthosteric Ligand	blt_on
13.33	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
13.16	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
13.16	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
12.90	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
12.90	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
12.90	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
12.90	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
12.90	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
12.90	Single	6GPX	MK0812	6GPX-CCR2-MK0812
12.90	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
12.90	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
12.90	Single	6PS6	Timolol	6PS6-β₂-Timolol
12.90	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
12.90	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
12.90	Single	7C4S	S1P	7C4S-S1P₃-S1P
12.90	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
12.90	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
12.90	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
12.90	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
12.90	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
12.90	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
12.90	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
12.90	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
12.90	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
12.90	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
12.90	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
12.90	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
12.90	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
12.90	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.90	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.90	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
12.90	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
12.90	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
12.90	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
12.77	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
12.50	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
12.50	Single	4DJH	JDTic	4DJH-κ-JDTic
12.50	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
12.50	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
12.50	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
12.50	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
12.50	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
12.50	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
12.50	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
12.50	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
12.50	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
12.50	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
12.50	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
12.50	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
12.50	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
12.50	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
12.50	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
12.50	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.50	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
12.50	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
12.50	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
12.50	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
12.50	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
12.50	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
12.50	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
12.50	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
12.50	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
12.50	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
12.50	Consensus	histamine_off	Orthosteric Ligand	h1_off
12.50	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
12.50	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
12.50	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
12.50	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
12.50	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
12.50	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
12.50	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
12.20	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
12.20	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
12.12	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
12.12	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
12.12	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
12.12	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
12.12	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
12.12	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
12.12	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
12.12	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
12.12	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.12	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
12.12	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
12.12	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
12.12	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
12.12	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
12.12	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
12.00	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
12.00	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
12.00	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
12.00	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
12.00	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
12.00	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
12.00	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
11.90	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
11.76	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
11.76	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
11.76	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
11.76	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
11.76	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.76	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.76	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.76	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
11.76	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
11.76	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
11.76	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
11.63	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
11.63	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
11.54	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
11.54	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
11.54	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
11.54	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.54	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
11.54	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
11.43	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.43	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
11.43	Consensus	class-d_off	Orthosteric Ligand	ste2_off
11.36	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
11.11	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
11.11	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
11.11	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
11.11	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
11.11	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
11.11	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
11.11	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
11.11	Single	7QA8	Peptide	7QA8-STE2-Peptide
11.11	Single	7QA8	Peptide	7QA8-STE2-Peptide
11.11	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
11.11	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
11.11	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
11.11	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
11.11	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
11.11	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
11.11	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
11.11	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
11.11	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
11.11	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
11.11	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.11	Consensus	class-d_off	Orthosteric Ligand	ste2_off
11.11	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
10.71	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
10.71	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
10.71	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
10.71	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
10.71	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
10.71	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
10.71	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
10.71	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
10.71	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
10.71	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
10.71	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
10.71	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
10.71	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
10.71	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
10.71	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.71	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
10.71	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.71	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
10.71	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
10.71	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
10.71	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
10.71	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
10.71	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
10.42	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
10.34	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
10.34	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
10.34	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
10.34	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
10.34	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
10.34	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
10.34	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
10.34	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
10.34	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
10.34	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
10.34	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
10.34	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
10.34	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
10.34	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
10.34	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
10.34	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.34	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
10.34	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
10.34	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
10.34	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
10.34	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
10.34	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
10.34	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
10.34	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
10.34	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
10.34	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
10.34	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.34	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
10.34	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
10.34	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.34	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.34	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.34	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
10.34	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
10.34	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
10.26	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
10.26	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
10.00	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
10.00	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
10.00	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
10.00	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
10.00	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
10.00	Single	6VI4	JDTic	6VI4-κ-JDTic
10.00	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
10.00	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
10.00	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
10.00	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
10.00	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
10.00	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
10.00	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
10.00	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
10.00	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
10.00	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
10.00	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
10.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
10.00	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
10.00	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
10.00	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.00	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
10.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
10.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.00	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
10.00	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.00	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
10.00	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
10.00	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
10.00	Consensus	sensory_off	Orthosteric Ligand	opsin_off
9.76	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
9.76	Consensus	class-d_on	Orthosteric Ligand	ste2_on
9.68	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
9.68	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
9.68	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
9.68	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
9.68	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
9.68	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
9.68	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
9.68	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
9.68	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
9.68	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
9.68	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.68	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
9.68	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
9.68	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
9.68	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
9.68	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
9.68	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
9.68	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
9.68	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
9.68	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
9.68	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
9.68	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
9.68	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
9.68	Consensus	hcar_off	Orthosteric Ligand	succinate_off
9.68	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
9.68	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
9.68	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
9.68	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
9.68	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
9.68	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
9.52	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
9.52	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
9.52	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
9.52	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
9.43	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
9.38	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
9.38	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
9.38	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
9.38	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
9.38	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.38	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
9.38	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
9.38	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
9.38	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
9.38	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
9.38	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.38	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
9.38	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
9.38	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.30	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
9.30	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
9.09	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
9.09	Single	6E59	L-760735	6E59-NK₁-L-760735
9.09	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
9.09	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
9.09	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
9.09	Single	7EPE	NAM563	7EPE-mGlu-NAM563
9.09	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
9.09	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
9.09	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
9.09	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
9.09	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.09	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
9.09	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.09	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
8.82	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
8.82	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
8.82	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
8.82	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.57	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
8.57	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
8.57	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
8.51	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
8.51	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
8.33	Single	8HS2	Fab046	8HS2-GPR20-Fab046
8.33	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
8.11	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
8.00	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
8.00	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
7.69	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
7.50	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
7.50	Consensus	class-d_on	Orthosteric Ligand	ste2_on
7.50	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
7.50	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
7.41	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
7.41	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
7.41	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
7.41	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
7.14	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
7.14	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
7.14	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
7.14	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
6.90	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
6.90	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
6.90	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
6.90	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
6.90	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
6.90	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.90	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
6.90	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.90	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
6.90	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
6.90	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
6.90	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
6.90	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
6.67	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
6.67	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
6.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.67	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
6.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
6.67	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
6.67	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
6.67	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
6.67	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
6.67	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
6.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
6.67	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
6.45	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
6.45	Single	6TPK	Retosiban	6TPK-OT-Retosiban
6.45	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
6.45	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.45	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
6.45	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
6.45	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
6.45	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
6.25	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
6.25	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.25	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
6.06	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
6.06	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
5.88	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
5.88	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.71	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.35	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
4.35	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
4.35	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
4.35	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
4.35	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
4.35	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
4.35	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.35	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.35	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
4.35	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
4.35	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
4.35	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
4.35	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.35	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.35	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.35	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
4.35	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
4.35	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
4.35	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
4.35	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
4.35	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
4.35	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
4.35	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
4.35	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
4.35	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
4.35	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.35	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.35	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
4.35	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
4.35	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.35	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
4.35	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
4.35	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
4.35	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
4.35	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
4.35	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
4.35	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Single	7FII	hCG	7FII-LH-hCG-6fuf
4.35	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
4.35	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
4.35	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
4.35	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
4.35	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.35	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.35	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.35	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
4.35	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
4.35	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
4.35	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.35	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
4.35	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
4.35	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
4.35	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.35	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.35	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.35	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
4.35	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
4.35	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
4.35	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
4.35	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
4.35	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
4.35	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
4.35	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
4.35	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
4.35	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
4.35	Single	7XW7	K1-70	7XW7-TSH-K1-70
4.35	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
4.35	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
4.35	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
4.35	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
4.35	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
4.35	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
4.35	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
4.35	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
4.35	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
4.35	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
4.35	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
4.35	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
4.35	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
4.35	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
4.35	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
4.35	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
4.35	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
4.35	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
4.35	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
4.35	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
4.35	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
4.35	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.35	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.35	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.35	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.35	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.35	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.35	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
4.35	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
4.35	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
4.35	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.35	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
4.35	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.35	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.35	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
4.35	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
4.35	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
4.35	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
4.35	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.35	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
4.35	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
4.35	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
4.35	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.35	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.35	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.35	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.35	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.35	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.35	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.35	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.35	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
4.35	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
4.35	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
4.35	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
4.35	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
4.35	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
4.35	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.35	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
4.35	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
4.35	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.35	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.35	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.35	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
4.35	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.35	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
4.35	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.35	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
4.35	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
4.35	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.35	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
4.35	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
4.35	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
4.35	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.35	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.35	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
4.35	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
4.35	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
4.35	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
4.35	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
4.35	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
4.35	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
4.35	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
4.35	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
4.17	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.17	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.17	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.17	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
4.17	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.17	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.17	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.17	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
4.17	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.17	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.00	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
4.00	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
3.85	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
3.85	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
3.85	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
3.85	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
3.85	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
3.85	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
3.85	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
3.85	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
3.70	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
3.70	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
3.70	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
3.70	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
3.57	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
3.45	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
3.45	Single	7F61	Cholesterol	7F61-H₃-PF-03654746-Cholesterol
3.45	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
3.45	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
3.45	Consensus	h3_on_allo	Other Ligand	7F61-H₃-PF-03654746-Cholesterol
3.33	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
3.33	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
3.33	Single	8J6Q	Compound 9n	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
3.33	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
3.33	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
3.33	Consensus	hca2_on_allo	Other Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
3.23	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
3.23	Single	8JHY	Compound 9n	8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2
3.23	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
3.12	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
3.12	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
3.12	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
3.12	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
3.03	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
2.94	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
2.94	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
2.86	Single	7P2L	4YI	7P2L-mGlu₅-4YI
2.86	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
2.86	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
2.86	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
2.78	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB

Consensus Members
	Id	Members
	gi_chemokine	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
	gi_chemerin	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2

Net Summary
I_min	2.18125
Number of Linked Nodes	940
Number of Links	1263
Number of Hubs	237
Number of Links mediated by Hubs	896
Number of Communities	17
Number of Nodes involved in Communities	334
Number of Links involved in Communities	548

Path Summary
Number Of Nodes in MetaPath	83
Number Of Links MetaPath	82
Number of Shortest Paths	8806129
Length Of Smallest Path	3
Average Path Length	31.989
Length of Longest Path	50
Minimum Path Strength	0.187083
Average Path Strength	4.67205
Maximum Path Strength	23.0231
Minimum Path Correlation	0.700625
Average Path Correlation	0.989206
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	2.17391
Average % Of Corr. Nodes	27.4226
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	66.6665
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gi_class-a	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download gi_protein.zip

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