psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	H:H:?1	R:R:F119	8.74	Yes	No	0	0	4
2	H:H:?1	R:R:W128	4.09	Yes	Yes	1	0	5
3	H:H:?1	R:R:N130	24.64	Yes	No	1	0	8
4	H:H:?1	R:R:M133	3.81	Yes	No	0	0	5
5	H:H:?2	R:R:Y71	6.31	No	No	0	0	3
6	H:H:?2	R:R:N73	30.8	No	No	0	0	4
7	L:L:C1	L:L:C7	7.28	No	No	2	0	0
8	L:L:C1	R:R:L298	9.52	No	Yes	2	0	6
9	L:L:C1	R:R:H302	7.37	No	Yes	2	0	6
10	L:L:N3	L:L:S2	4.47	No	No	0	0	0
11	L:L:S2	R:R:E294	5.75	No	No	0	0	3
12	L:L:N3	R:R:W361	16.95	No	No	0	0	4
13	L:L:N3	R:R:R362	7.23	No	Yes	0	0	4
14	L:L:L4	R:R:M306	4.24	No	No	0	0	4
15	L:L:L4	R:R:W361	3.42	No	No	0	0	4
16	L:L:S5	R:R:F356	5.28	No	Yes	0	0	7
17	L:L:T6	R:R:Y234	7.49	Yes	Yes	2	0	7
18	L:L:T6	R:R:H302	5.48	Yes	Yes	2	0	6
19	L:L:T6	R:R:V305	4.76	Yes	No	2	0	7
20	L:L:T6	R:R:M306	6.02	Yes	No	0	0	4
21	L:L:T6	R:R:F356	6.49	Yes	Yes	2	0	7
22	L:L:C7	R:R:V293	3.42	No	No	0	0	6
23	L:L:C7	R:R:H302	8.85	No	Yes	2	0	6
24	L:L:V8	R:R:H377	4.15	No	Yes	0	0	7
25	L:L:L9	R:R:I198	5.71	No	Yes	0	0	7
26	L:L:L9	R:R:H381	5.14	No	Yes	0	0	9
27	L:L:E15	L:L:K11	8.1	No	No	0	0	0
28	L:L:K11	R:R:R362	4.95	No	Yes	0	0	4
29	L:L:L12	L:L:L16	5.54	No	Yes	3	0	0
30	L:L:L12	R:R:L148	4.15	No	No	3	0	5
31	L:L:L12	R:R:H377	5.14	No	Yes	3	0	7
32	L:L:S13	R:R:V206	4.85	No	No	0	0	3
33	L:L:Q14	R:R:V293	10.03	No	No	0	0	6
34	L:L:Q14	R:R:E294	10.19	No	No	0	0	3
35	L:L:E15	L:L:K18	5.4	No	No	0	0	0
36	L:L:L16	R:R:Y146	7.03	Yes	Yes	3	0	2
37	L:L:L16	R:R:Y149	4.69	Yes	Yes	3	0	5
38	L:L:H17	L:L:T21	12.32	Yes	No	1	0	0
39	L:L:H17	L:L:Y22	8.71	Yes	Yes	1	0	0
40	L:L:H17	R:R:V212	9.69	Yes	No	1	0	3
41	L:L:H17	R:R:L291	7.71	Yes	No	1	0	6
42	L:L:K18	R:R:P100	5.02	No	Yes	0	0	4
43	L:L:L19	R:R:K141	7.05	No	No	0	0	3
44	L:L:Q20	R:R:Y146	6.76	No	Yes	0	0	2
45	L:L:T21	L:L:Y22	7.49	No	Yes	1	0	0
46	L:L:T21	R:R:G209	3.64	No	No	0	0	3
47	L:L:Y22	R:R:P38	5.56	Yes	No	1	0	5
48	L:L:Y22	R:R:L40	5.86	Yes	No	0	0	5
49	L:L:Y22	R:R:Y41	5.96	Yes	Yes	1	0	3
50	L:L:Y22	R:R:P100	6.95	Yes	Yes	1	0	4
51	L:L:R24	L:L:T27	3.88	No	No	1	0	0
52	L:L:R24	R:R:N135	3.62	No	Yes	1	0	3
53	L:L:T25	R:R:W79	3.64	Yes	Yes	1	0	6
54	L:L:T25	R:R:F99	3.89	Yes	Yes	1	0	5
55	L:L:T25	R:R:D101	8.67	Yes	Yes	1	0	4
56	L:L:T25	R:R:F102	7.78	Yes	Yes	1	0	4
57	L:L:T27	R:R:N135	4.39	No	Yes	1	0	3
58	L:L:G28	R:R:W128	4.22	No	Yes	0	0	5
59	L:L:S29	R:R:H121	11.16	No	Yes	1	0	4
60	L:L:S29	R:R:E123	5.75	No	No	1	0	4
61	L:L:S29	R:R:N124	8.94	No	No	0	0	5
62	L:L:G30	R:R:R126	4.5	No	No	0	0	4
63	L:L:?33	L:L:P32	12.19	Yes	No	1	0	0
64	L:L:P32	R:R:D77	9.66	No	Yes	1	0	9
65	L:L:P32	R:R:W79	21.62	No	Yes	1	0	6
66	L:L:?33	R:R:D77	10.08	Yes	Yes	1	0	9
67	L:L:?33	R:R:W128	5.64	Yes	Yes	1	0	5
68	L:L:?33	R:R:S129	7.43	Yes	Yes	1	0	7
69	L:L:?33	R:R:Y131	5.8	Yes	Yes	1	0	5
70	R:R:P38	R:R:Y41	5.56	No	Yes	1	5	3
71	R:R:F39	R:R:V43	6.55	No	No	0	4	2
72	R:R:D287	R:R:F39	4.78	Yes	No	0	3	4
73	R:R:P100	R:R:Y41	9.74	Yes	Yes	1	4	3
74	R:R:D50	R:R:K47	11.06	No	No	0	2	4
75	R:R:M48	R:R:Y98	14.37	No	No	0	6	4
76	R:R:M49	R:R:Y53	5.99	No	No	0	4	1
77	R:R:Q52	R:R:Y53	7.89	No	No	0	6	1
78	R:R:Q52	R:R:Y56	7.89	No	No	4	6	3
79	R:R:Q52	R:R:W76	19.71	No	Yes	4	6	8
80	R:R:K54	R:R:R58	6.19	No	No	0	4	3
81	R:R:C55	R:R:C81	7.28	No	No	4	9	9
82	R:R:T75	R:R:Y56	3.75	No	No	0	5	3
83	R:R:W76	R:R:Y56	3.86	Yes	No	4	8	3
84	R:R:M59	R:R:R74	13.65	No	Yes	0	5	4
85	R:R:L62	R:R:P63	4.93	No	No	0	3	1
86	R:R:D83	R:R:L62	5.43	No	No	0	5	3
87	R:R:Y65	R:R:Y71	3.97	No	No	0	3	3
88	R:R:D84	R:R:Y65	12.64	No	No	0	4	3
89	R:R:P86	R:R:Y65	6.95	No	No	0	2	3
90	R:R:G69	R:R:P70	4.06	No	No	0	1	1
91	R:R:A87	R:R:P70	3.74	No	No	0	4	1
92	R:R:G116	R:R:P70	4.06	No	No	0	9	1
93	R:R:C72	R:R:K110	3.23	No	Yes	5	9	8
94	R:R:C112	R:R:C72	7.28	No	No	5	9	9
95	R:R:C72	R:R:W118	5.22	No	Yes	5	9	9
96	R:R:D83	R:R:R74	10.72	No	Yes	0	5	4
97	R:R:D84	R:R:R74	8.34	No	Yes	0	4	4
98	R:R:G78	R:R:W76	5.63	No	Yes	0	5	8
99	R:R:C81	R:R:W76	5.22	No	Yes	4	9	8
100	R:R:D77	R:R:S129	7.36	Yes	Yes	1	9	7
101	R:R:D77	R:R:Y131	5.75	Yes	Yes	1	9	5
102	R:R:F99	R:R:W79	13.03	Yes	Yes	1	5	6
103	R:R:F102	R:R:W79	5.01	Yes	Yes	1	4	6
104	R:R:W79	R:R:Y131	15.43	Yes	Yes	1	6	5
105	R:R:L80	R:R:P96	14.78	No	Yes	1	5	9
106	R:R:L80	R:R:Y131	7.03	No	Yes	1	5	5
107	R:R:S91	R:R:W82	3.71	No	Yes	0	5	9
108	R:R:Q93	R:R:W82	9.86	No	Yes	0	6	9
109	R:R:V108	R:R:W82	3.68	Yes	Yes	0	7	9
110	R:R:K110	R:R:W82	32.49	Yes	Yes	0	8	9
111	R:R:S129	R:R:W82	6.18	Yes	Yes	0	7	9
112	R:R:P86	R:R:T85	5.25	No	No	6	2	7
113	R:R:T85	R:R:V89	4.76	No	No	6	7	5
114	R:R:S91	R:R:T85	6.4	No	No	0	5	7
115	R:R:P86	R:R:V89	3.53	No	No	6	2	5
116	R:R:G88	R:R:Y111	4.35	No	Yes	7	8	4
117	R:R:E114	R:R:G88	6.55	No	No	7	2	8
118	R:R:L90	R:R:Y111	11.72	No	Yes	0	4	4
119	R:R:K107	R:R:Y92	9.55	No	No	0	3	4
120	R:R:F94	R:R:K107	3.72	No	No	0	3	3
121	R:R:C95	R:R:V108	5.12	No	Yes	1	9	7
122	R:R:C134	R:R:C95	7.28	No	No	1	9	9
123	R:R:P96	R:R:Y98	8.34	Yes	No	0	9	4
124	R:R:F102	R:R:P96	5.78	Yes	Yes	1	4	9
125	R:R:P96	R:R:Y131	4.17	Yes	Yes	1	9	5
126	R:R:D97	R:R:P104	14.49	No	No	0	2	3
127	R:R:F99	R:R:Y98	5.16	Yes	No	0	5	4
128	R:R:F102	R:R:F99	18.22	Yes	Yes	1	4	5
129	R:R:D101	R:R:P100	3.22	Yes	Yes	1	4	4
130	R:R:D101	R:R:F102	3.58	Yes	Yes	1	4	4
131	R:R:D101	R:R:N135	9.42	Yes	Yes	1	4	3
132	R:R:F102	R:R:Y131	6.19	Yes	Yes	1	4	5
133	R:R:C134	R:R:F102	6.98	No	Yes	1	9	4
134	R:R:F102	R:R:N135	10.87	Yes	Yes	1	4	3
135	R:R:D103	R:R:P104	8.05	Yes	No	0	3	3
136	R:R:D103	R:R:S105	8.83	Yes	No	0	3	1
137	R:R:D103	R:R:E106	5.2	Yes	Yes	0	3	4
138	R:R:K366	R:R:S105	4.59	No	No	0	3	1
139	R:R:E106	R:R:M133	5.41	Yes	No	0	4	5
140	R:R:V108	R:R:Y131	12.62	Yes	Yes	1	7	5
141	R:R:C134	R:R:V108	3.42	No	Yes	1	9	7
142	R:R:C112	R:R:K110	3.23	No	Yes	5	9	8
143	R:R:K110	R:R:W118	5.8	Yes	Yes	5	8	9
144	R:R:D113	R:R:Y111	17.24	No	Yes	0	5	4
145	R:R:E114	R:R:Y111	3.37	No	Yes	7	2	4
146	R:R:C112	R:R:W118	3.92	No	Yes	5	9	9
147	R:R:D113	R:R:F119	3.58	No	No	0	5	4
148	R:R:T127	R:R:W118	12.13	No	Yes	0	4	9
149	R:R:K120	R:R:P122	3.35	No	No	0	1	5
150	R:R:K120	R:R:N125	19.58	No	No	0	1	7
151	R:R:H121	R:R:P122	9.15	Yes	No	0	4	5
152	R:R:E123	R:R:H121	9.85	No	Yes	1	4	4
153	R:R:H121	R:R:W128	11.64	Yes	Yes	1	4	5
154	R:R:N124	R:R:R126	22.9	No	No	0	5	4
155	R:R:N130	R:R:W128	5.65	No	Yes	1	8	5
156	R:R:S129	R:R:Y131	7.63	Yes	Yes	1	7	5
157	R:R:N130	R:R:T132	8.77	No	No	0	8	6
158	R:R:P139	R:R:T138	5.25	No	No	0	3	2
159	R:R:E140	R:R:K143	6.75	No	No	0	2	1
160	R:R:L142	R:R:Y146	5.86	No	Yes	0	2	2
161	R:R:Y146	R:R:Y149	3.97	Yes	Yes	3	2	5
162	R:R:V147	R:R:Y374	6.31	No	No	0	4	6
163	R:R:L148	R:R:Y374	4.69	No	No	0	5	6
164	R:R:H377	R:R:L148	12.86	Yes	No	3	7	5
165	R:R:Y149	R:R:Y150	8.94	Yes	No	0	5	4
166	R:R:I153	R:R:Y149	6.04	No	Yes	3	7	5
167	R:R:L202	R:R:Y149	7.03	No	Yes	0	7	5
168	R:R:F382	R:R:L151	3.65	Yes	No	0	7	5
169	R:R:A152	R:R:H381	7.32	No	Yes	0	7	9
170	R:R:I153	R:R:I199	4.42	No	No	3	7	7
171	R:R:F382	R:R:G155	9.03	Yes	No	0	7	8
172	R:R:H156	R:R:S195	11.16	No	No	0	7	7
173	R:R:H156	R:R:I198	13.26	No	Yes	0	7	7
174	R:R:H156	R:R:H381	10.75	No	Yes	0	7	9
175	R:R:F385	R:R:L158	15.83	Yes	No	0	5	4
176	R:R:G384	R:R:S159	3.71	No	No	0	9	9
177	R:R:F161	R:R:I165	6.28	No	No	0	4	5
178	R:R:F385	R:R:T162	6.49	Yes	No	0	5	6
179	R:R:A388	R:R:T162	3.36	No	No	0	8	6
180	R:R:F393	R:R:T162	3.89	Yes	No	0	8	6
181	R:R:F188	R:R:L163	4.87	Yes	Yes	0	8	8
182	R:R:L163	R:R:Y191	5.86	Yes	Yes	2	8	8
183	R:R:I192	R:R:L163	4.28	No	Yes	0	7	8
184	R:R:G384	R:R:L163	3.42	No	Yes	2	9	8
185	R:R:I192	R:R:V164	6.14	No	No	0	7	4
186	R:R:F393	R:R:I165	3.77	Yes	No	0	8	5
187	R:R:F188	R:R:S166	7.93	Yes	No	0	8	9
188	R:R:A388	R:R:S166	3.42	No	No	0	8	9
189	R:R:C392	R:R:S166	3.44	No	No	0	9	9
190	R:R:F173	R:R:I169	6.28	Yes	No	0	7	8
191	R:R:C392	R:R:I169	4.91	No	No	0	9	8
192	R:R:F170	R:R:L176	4.87	No	No	0	8	9
193	R:R:F170	R:R:V181	10.49	No	No	0	8	9
194	R:R:F170	R:R:F188	5.36	No	Yes	0	8	8
195	R:R:F172	R:R:F173	12.86	No	Yes	0	2	7
196	R:R:F173	R:R:Q405	9.37	Yes	No	0	7	4
197	R:R:L176	R:R:V398	7.45	No	No	0	9	9
198	R:R:L176	R:R:T401	4.42	No	Yes	0	9	7
199	R:R:C178	R:R:R180	5.57	No	No	0	8	9
200	R:R:C178	R:R:V181	3.42	No	No	0	8	9
201	R:R:Q179	R:R:Y243	6.76	No	Yes	0	7	8
202	R:R:L259	R:R:Q179	6.65	Yes	No	0	5	7
203	R:R:H184	R:R:R180	5.64	No	No	0	9	9
204	R:R:E397	R:R:R180	9.3	No	No	0	9	9
205	R:R:L183	R:R:W236	4.56	No	Yes	0	8	9
206	R:R:L183	R:R:Y243	5.86	No	Yes	0	8	8
207	R:R:L183	R:R:L259	5.54	No	Yes	0	8	5
208	R:R:E240	R:R:H184	11.08	No	No	0	9	9
209	R:R:H184	R:R:Y391	5.44	No	Yes	0	9	8
210	R:R:N186	R:R:W236	13.56	No	Yes	2	9	9
211	R:R:N186	R:R:Y263	5.81	No	No	2	9	5
212	R:R:N186	R:R:W267	4.52	No	Yes	2	9	9
213	R:R:M187	R:R:Y191	8.38	No	Yes	0	8	8
214	R:R:E240	R:R:M187	10.83	No	No	0	9	8
215	R:R:F188	R:R:V387	3.93	Yes	No	0	8	9
216	R:R:L189	R:R:L193	5.54	No	No	0	3	6
217	R:R:L189	R:R:W267	5.69	No	Yes	0	3	9
218	R:R:N233	R:R:T190	7.31	Yes	No	2	9	9
219	R:R:T190	R:R:W236	6.06	No	Yes	2	9	9
220	R:R:T190	R:R:W267	4.85	No	Yes	2	9	9
221	R:R:N233	R:R:Y191	18.61	Yes	Yes	2	9	8
222	R:R:M237	R:R:Y191	5.99	Yes	Yes	2	9	8
223	R:R:Q383	R:R:Y191	13.53	Yes	Yes	2	9	8
224	R:R:G384	R:R:Y191	8.69	No	Yes	2	9	8
225	R:R:V387	R:R:Y191	5.05	No	Yes	0	9	8
226	R:R:L193	R:R:M229	8.48	No	No	0	6	4
227	R:R:I198	R:R:N194	7.08	Yes	No	0	7	8
228	R:R:N194	R:R:N233	9.54	No	Yes	0	8	9
229	R:R:H226	R:R:I198	3.98	No	Yes	0	6	7
230	R:R:H201	R:R:V205	11.07	No	No	0	6	7
231	R:R:E204	R:R:V203	4.28	No	No	0	4	3
232	R:R:P207	R:R:V206	3.53	No	No	0	3	3
233	R:R:E210	R:R:N208	3.94	No	No	0	3	3
234	R:R:L211	R:R:N208	9.61	Yes	No	0	1	3
235	R:R:L211	R:R:R214	6.07	Yes	No	0	1	4
236	R:R:L211	R:R:P216	3.28	Yes	No	0	1	4
237	R:R:C289	R:R:V212	8.54	No	No	0	9	3
238	R:R:L291	R:R:V212	4.47	No	No	1	6	3
239	R:R:D215	R:R:K220	6.91	No	No	0	6	7
240	R:R:D215	R:R:N288	10.77	No	No	0	6	4
241	R:R:C219	R:R:C289	7.28	No	No	0	9	9
242	R:R:K220	R:R:N286	5.6	No	No	2	7	7
243	R:R:K220	R:R:W290	23.21	No	Yes	2	7	9
244	R:R:H223	R:R:Q227	11.13	No	Yes	0	5	7
245	R:R:H223	R:R:W290	12.7	No	Yes	0	5	9
246	R:R:F224	R:R:F225	4.29	Yes	No	0	5	5
247	R:R:F224	R:R:T274	5.19	Yes	No	0	5	6
248	R:R:H226	R:R:Q227	3.71	No	Yes	0	6	7
249	R:R:H226	R:R:M230	3.94	No	No	0	6	6
250	R:R:I301	R:R:Q227	5.49	Yes	Yes	2	7	7
251	R:R:H302	R:R:Q227	4.95	Yes	Yes	2	6	7
252	R:R:C232	R:R:Y228	9.41	No	No	0	8	8
253	R:R:L271	R:R:Y228	8.21	No	No	0	4	8
254	R:R:T274	R:R:Y228	3.75	No	No	0	6	8
255	R:R:M229	R:R:W267	3.49	No	Yes	0	4	9
256	R:R:M230	R:R:Y234	7.18	No	Yes	0	6	7
257	R:R:A231	R:R:P270	3.74	No	Yes	0	5	9
258	R:R:C232	R:R:W267	3.92	No	Yes	0	8	9
259	R:R:C232	R:R:P270	7.53	No	Yes	0	8	9
260	R:R:M237	R:R:N233	4.21	Yes	Yes	2	9	9
261	R:R:M237	R:R:Y234	3.59	Yes	Yes	2	9	7
262	R:R:V305	R:R:Y234	10.09	No	Yes	2	7	7
263	R:R:F356	R:R:Y234	12.38	Yes	Yes	2	7	7
264	R:R:F235	R:R:F269	9.65	Yes	No	8	5	3
265	R:R:F235	R:R:P270	5.78	Yes	Yes	8	5	9
266	R:R:A308	R:R:F235	4.16	No	Yes	0	7	5
267	R:R:C239	R:R:W236	7.84	No	Yes	0	7	9
268	R:R:W236	R:R:Y263	3.86	Yes	No	2	9	5
269	R:R:G266	R:R:W236	7.04	No	Yes	0	9	9
270	R:R:W236	R:R:W267	12.18	Yes	Yes	2	9	9
271	R:R:M237	R:R:Q383	6.8	Yes	Yes	2	9	9
272	R:R:I242	R:R:L238	7.14	No	No	0	7	8
273	R:R:L238	R:R:L265	4.15	No	No	0	8	7
274	R:R:L238	R:R:N312	5.49	No	No	0	8	9
275	R:R:C239	R:R:Y262	5.38	No	Yes	0	7	7
276	R:R:C239	R:R:L265	4.76	No	No	0	7	7
277	R:R:E240	R:R:L351	9.28	No	No	0	9	9
278	R:R:G241	R:R:N312	5.09	No	No	0	8	9
279	R:R:I242	R:R:Y262	4.84	No	Yes	0	7	7
280	R:R:F315	R:R:I242	3.77	No	No	0	8	7
281	R:R:L247	R:R:Y243	7.03	No	Yes	0	8	8
282	R:R:Y243	R:R:Y262	6.95	Yes	Yes	0	8	7
283	R:R:I319	R:R:L244	5.71	No	No	0	9	9
284	R:R:H245	R:R:V249	12.45	No	No	0	8	6
285	R:R:F315	R:R:H245	26.02	No	No	0	8	8
286	R:R:H245	R:R:N318	8.93	No	No	0	8	8
287	R:R:Q257	R:R:T246	5.67	No	No	0	5	7
288	R:R:A251	R:R:T254	5.03	No	No	0	6	6
289	R:R:E255	R:R:K256	6.75	No	No	0	6	5
290	R:R:K256	R:R:R258	7.43	No	No	0	5	5
291	R:R:Q257	R:R:Y262	4.51	No	Yes	0	5	7
292	R:R:R258	R:R:R260	5.33	No	No	0	5	3
293	R:R:L259	R:R:Y262	3.52	Yes	Yes	0	5	7
294	R:R:L259	R:R:Y263	8.21	Yes	No	0	5	5
295	R:R:R260	R:R:W261	10	No	No	0	3	2
296	R:R:F269	R:R:P270	4.33	No	Yes	8	3	9
297	R:R:P273	R:R:V272	5.3	No	No	0	6	4
298	R:R:I301	R:R:T274	6.08	Yes	No	0	7	6
299	R:R:I276	R:R:I300	4.42	No	No	0	5	8
300	R:R:H277	R:R:R281	12.41	No	Yes	2	7	7
301	R:R:H277	R:R:L298	5.14	No	Yes	2	7	6
302	R:R:H277	R:R:I301	10.61	No	Yes	2	7	7
303	R:R:T280	R:R:Y284	4.99	No	No	0	4	2
304	R:R:L297	R:R:T280	8.84	No	No	0	4	4
305	R:R:F285	R:R:R281	6.41	Yes	Yes	2	6	7
306	R:R:D287	R:R:R281	3.57	Yes	Yes	2	3	7
307	R:R:R281	R:R:W290	13	Yes	Yes	2	7	9
308	R:R:R281	R:R:T295	6.47	Yes	No	2	7	4
309	R:R:L298	R:R:R281	3.64	Yes	Yes	2	6	7
310	R:R:V283	R:R:Y284	13.88	No	No	0	3	2
311	R:R:D287	R:R:F285	5.97	Yes	Yes	2	3	6
312	R:R:F285	R:R:S292	3.96	Yes	No	2	6	4
313	R:R:F285	R:R:T295	15.56	Yes	No	2	6	4
314	R:R:N286	R:R:W290	4.52	No	Yes	2	7	9
315	R:R:D287	R:R:W290	4.47	Yes	Yes	2	3	9
316	R:R:D287	R:R:S292	4.42	Yes	No	2	3	4
317	R:R:L297	R:R:T295	4.42	No	No	0	4	4
318	R:R:H296	R:R:Y299	6.53	No	No	0	2	7
319	R:R:H302	R:R:L298	3.86	Yes	Yes	2	6	6
320	R:R:H302	R:R:I301	7.95	Yes	Yes	2	6	7
321	R:R:G303	R:R:P304	4.06	No	No	0	4	9
322	R:R:F356	R:R:L309	3.65	Yes	No	0	7	7
323	R:R:F315	R:R:V311	5.24	No	No	0	8	6
324	R:R:L352	R:R:N312	8.24	No	No	0	9	9
325	R:R:F313	R:R:L317	8.53	No	No	0	6	5
326	R:R:F313	R:R:V357	6.55	No	No	0	6	7
327	R:R:L316	R:R:L348	4.15	No	No	0	9	9
328	R:R:I354	R:R:L316	5.71	Yes	No	0	6	9
329	R:R:N318	R:R:R321	7.23	No	No	0	8	8
330	R:R:T345	R:R:V320	4.76	No	No	0	9	7
331	R:R:L323	R:R:M327	4.24	No	Yes	0	9	7
332	R:R:E332	R:R:M327	12.18	No	Yes	0	5	7
333	R:R:M327	R:R:M337	7.22	Yes	No	0	7	7
334	R:R:K340	R:R:M327	5.76	No	Yes	0	8	7
335	R:R:M337	R:R:R328	7.44	No	No	0	7	6
336	R:R:E332	R:R:H336	6.15	No	No	0	5	6
337	R:R:E334	R:R:Y338	4.49	No	No	0	6	7
338	R:R:H336	R:R:L339	6.43	No	No	0	6	6
339	R:R:H336	R:R:K340	9.17	No	No	0	6	8
340	R:R:I347	R:R:I390	5.89	No	No	0	8	8
341	R:R:L348	R:R:Y391	3.52	No	Yes	0	9	8
342	R:R:P350	R:R:V349	3.53	No	No	0	9	8
343	R:R:I354	R:R:V349	9.22	Yes	No	0	6	8
344	R:R:P350	R:R:V387	3.53	No	No	0	9	9
345	R:R:L351	R:R:Y391	18.76	No	Yes	0	9	8
346	R:R:I354	R:R:L352	4.28	Yes	No	0	6	9
347	R:R:G353	R:R:Q355	4.93	No	Yes	0	9	8
348	R:R:F356	R:R:Q355	9.37	Yes	Yes	2	7	8
349	R:R:L379	R:R:Q355	5.32	No	Yes	0	5	8
350	R:R:Q355	R:R:Q383	10.24	Yes	Yes	2	8	9
351	R:R:F356	R:R:I380	11.3	Yes	No	0	7	6
352	R:R:F356	R:R:Q383	4.68	Yes	Yes	2	7	9
353	R:R:F359	R:R:V358	7.87	No	No	0	6	5
354	R:R:F359	R:R:Y372	4.13	No	Yes	9	6	7
355	R:R:F359	R:R:M376	3.73	No	No	9	6	7
356	R:R:G369	R:R:R362	4.5	No	Yes	0	4	4
357	R:R:R362	R:R:Y372	8.23	Yes	Yes	0	4	7
358	R:R:D373	R:R:R362	11.91	No	Yes	0	5	4
359	R:R:L368	R:R:P363	3.28	No	No	0	3	7
360	R:R:P363	R:R:Y372	8.34	No	Yes	0	7	7
361	R:R:M367	R:R:N365	4.21	No	No	0	4	4
362	R:R:L368	R:R:N365	6.87	No	No	0	3	4
363	R:R:I371	R:R:M367	4.37	No	No	0	5	4
364	R:R:M376	R:R:Y372	14.37	No	Yes	9	7	7
365	R:R:D373	R:R:H377	3.78	No	Yes	0	5	7
366	R:R:I380	R:R:M376	4.37	No	No	0	6	7
367	R:R:H377	R:R:H381	9.55	Yes	Yes	0	7	9
368	R:R:F382	R:R:F386	3.22	Yes	No	0	7	5
369	R:R:F385	R:R:F386	5.36	Yes	No	0	5	5
370	R:R:F385	R:R:T389	6.49	Yes	No	0	5	5
371	R:R:F393	R:R:T389	3.89	Yes	No	0	8	5
372	R:R:I390	R:R:Y391	7.25	No	Yes	0	8	8
373	R:R:C392	R:R:F393	4.19	No	Yes	0	9	8
374	R:R:E397	R:R:N395	11.83	No	No	0	9	9
375	R:R:N395	R:R:V398	8.87	No	No	0	9	9
376	R:R:Q405	R:R:Q408	6.4	No	No	0	4	7
377	R:R:V249	R:R:V250	3.21	No	No	0	6	5
378	R:R:S175	R:R:T401	3.2	No	Yes	0	8	7
379	R:R:C219	R:R:L211	3.17	No	Yes	0	9	1
380	L:L:L16	R:R:A145	3.15	Yes	No	0	0	4
381	R:R:I160	R:R:S195	3.1	No	No	0	5	7
382	R:R:I221	R:R:V217	3.07	No	No	0	4	3
383	R:R:K185	R:R:V181	3.04	No	No	0	6	9
384	R:R:I279	R:R:T275	3.04	No	No	0	3	3
385	R:R:I300	R:R:T280	3.04	No	No	0	8	4
386	R:R:K326	R:R:V322	3.04	No	No	0	9	8
387	R:R:K141	R:R:T138	3	No	No	0	3	2
388	R:R:L291	R:R:V205	2.98	No	No	0	6	7
389	R:R:L316	R:R:V320	2.98	No	No	0	9	7
390	R:R:L259	R:R:T182	2.95	Yes	No	0	5	5
391	L:L:N26	L:L:T31	2.92	No	No	0	0	0
392	R:R:I192	R:R:M196	2.92	No	No	0	7	4
393	R:R:I197	R:R:M229	2.92	No	No	0	5	4
394	R:R:I347	R:R:K343	2.91	No	No	0	8	8
395	R:R:F269	R:R:P273	2.89	No	No	0	3	6
396	R:R:I200	R:R:L222	2.85	No	No	0	6	6
397	R:R:Q257	R:R:T254	2.83	No	No	0	5	6
398	R:R:K185	R:R:L167	2.82	No	No	0	6	6
399	R:R:C55	R:R:R74	2.79	No	Yes	4	9	4
400	R:R:C81	R:R:R74	2.79	No	Yes	4	9	4
401	L:L:P23	R:R:Y41	2.78	No	Yes	0	0	3
402	R:R:P207	R:R:Y149	2.78	No	Yes	0	3	5
403	L:L:L19	R:R:L142	2.77	No	No	0	0	2
404	R:R:D103	R:R:K141	2.77	Yes	No	0	3	3
405	R:R:A278	R:R:F224	2.77	No	Yes	0	6	5
406	R:R:K256	R:R:Q179	2.71	No	No	0	5	7
407	R:R:F382	R:R:V154	2.62	Yes	No	0	7	6
408	R:R:F173	R:R:V402	2.62	Yes	No	0	7	5
409	R:R:F314	R:R:V310	2.62	No	No	0	5	4
410	R:R:A51	R:R:W76	2.59	No	Yes	0	8	8
411	R:R:F224	R:R:T275	2.59	Yes	No	0	5	3
412	R:R:R404	R:R:T401	2.59	No	Yes	0	7	7
413	R:R:H201	R:R:L222	2.57	No	No	0	6	6
414	R:R:V203	R:R:Y149	2.52	No	Yes	0	3	5
415	R:R:F225	R:R:I221	2.51	No	No	0	5	4
416	R:R:F313	R:R:I354	2.51	No	Yes	0	6	6
417	R:R:F314	R:R:L317	2.44	No	No	0	5	5
418	L:L:T31	R:R:W79	2.43	No	Yes	0	0	6
419	R:R:M337	R:R:Y338	2.39	No	No	0	7	7
420	R:R:K370	R:R:Y374	2.39	No	No	0	4	6
421	R:R:E106	R:R:F137	2.33	Yes	No	0	4	1
422	R:R:E210	R:R:R213	2.33	No	No	0	3	2
423	R:R:L264	R:R:W261	2.28	No	No	0	3	2
424	R:R:G268	R:R:P270	2.03	No	Yes	0	6	9
425	R:R:A87	R:R:G88	1.95	No	No	0	4	8
426	R:R:W361	R:R:Y299	1.93	No	No	0	4	7
427	L:L:G10	R:R:V293	1.84	No	No	0	0	6
428	R:R:G44	R:R:V43	1.84	No	No	0	4	2
429	L:L:S5	R:R:P360	1.78	No	No	0	0	5
430	R:R:P216	R:R:S218	1.78	No	No	0	4	3
431	R:R:G241	R:R:L244	1.71	No	No	0	8	9
432	R:R:A341	R:R:V324	1.7	No	No	0	9	5
433	R:R:C394	R:R:T389	1.69	No	No	0	5	5
434	R:R:K37	R:R:P38	1.67	No	No	0	4	5
435	R:R:E68	R:R:G69	1.64	No	No	0	1	1
436	R:R:A51	R:R:K47	1.61	No	No	0	8	4
437	R:R:V249	R:R:V322	1.6	No	No	0	6	8
438	R:R:V320	R:R:V324	1.6	No	No	0	7	5
439	R:R:T325	R:R:V324	1.59	No	No	0	7	5
440	R:R:A344	R:R:L323	1.58	No	No	0	9	9
441	R:R:T400	R:R:T401	1.57	No	Yes	0	4	7
442	R:R:A282	R:R:N286	1.56	No	No	0	3	7
443	R:R:I153	R:R:S157	1.55	No	No	3	7	7
444	R:R:I199	R:R:S157	1.55	No	No	3	7	7
445	R:R:I248	R:R:V322	1.54	No	No	0	7	8
446	R:R:I371	R:R:V375	1.54	No	No	0	5	4
447	R:R:K37	R:R:V42	1.52	No	No	0	4	1
448	R:R:K185	R:R:V171	1.52	No	No	0	6	4
449	R:R:M346	R:R:V342	1.52	No	No	0	8	8
450	R:R:M346	R:R:V349	1.52	No	No	0	8	8
451	R:R:L151	R:R:S378	1.5	No	No	0	5	5
452	R:R:L90	R:R:T109	1.47	No	No	0	4	5
453	R:R:N396	R:R:T400	1.46	No	No	0	6	4
454	R:R:F235	R:R:P304	1.44	Yes	No	0	5	9
455	R:R:K370	R:R:N144	1.4	No	No	0	4	4
456	R:R:A136	R:R:F137	1.39	No	No	0	2	1
457	R:R:K403	R:R:Q399	1.36	No	No	0	6	7
458	R:R:E106	R:R:K107	1.35	Yes	No	0	4	3
459	R:R:E329	R:R:K326	1.35	No	No	0	6	9
460	R:R:D57	R:R:Q60	1.31	No	No	0	4	3
461	R:R:E140	R:R:N144	1.31	No	No	0	2	4
462	R:R:V117	R:R:W118	1.23	No	Yes	0	5	9
463	R:R:L62	R:R:R58	1.21	No	No	0	3	3
464	R:R:Q61	R:R:R58	1.17	No	No	0	3	3
465	R:R:R45	R:R:Y41	1.03	No	Yes	0	7	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	H:H:?1	10.32	4	1	0
2	L:L:T6	6.048	5	2	0
3	L:L:L16	5.1025	4	3	0
4	L:L:H17	9.6075	4	1	0
5	L:L:Y22	6.755	6	1	0
6	L:L:T25	5.995	4	1	0
7	L:L:?33	8.228	5	1	0
8	R:R:Y41	5.014	5	1	3
9	R:R:R74	7.658	5	4	4
10	R:R:W76	7.402	5	4	8
11	R:R:D77	8.2125	4	1	9
12	R:R:W79	10.1933	6	1	6
13	R:R:W82	11.184	5	0	9
14	R:R:P96	8.2675	4	1	9
15	R:R:F99	10.075	4	1	5
16	R:R:P100	6.2325	4	1	4
17	R:R:D101	6.2225	4	1	4
18	R:R:F102	8.05125	8	1	4
19	R:R:D103	6.2125	4	0	3
20	R:R:E106	3.5725	4	0	4
21	R:R:V108	6.21	4	1	7
22	R:R:K110	11.1875	4	5	8
23	R:R:Y111	9.17	4	7	4
24	R:R:W118	5.66	5	5	9
25	R:R:H121	10.45	4	1	4
26	R:R:W128	6.248	5	1	5
27	R:R:S129	7.15	4	1	7
28	R:R:Y131	8.0775	8	1	5
29	R:R:N135	7.075	4	1	3
30	R:R:Y146	5.905	4	3	2
31	R:R:Y149	5.13857	7	3	5
32	R:R:L163	4.6075	4	2	8
33	R:R:F173	7.7825	4	0	7
34	R:R:F188	5.5225	4	0	8
35	R:R:Y191	9.44428	7	2	8
36	R:R:I198	7.5075	4	0	7
37	R:R:L211	5.5325	4	0	1
38	R:R:F224	3.71	4	0	5
39	R:R:Q227	6.32	4	2	7
40	R:R:N233	9.9175	4	2	9
41	R:R:Y234	8.146	5	2	7
42	R:R:F235	5.2575	4	8	5
43	R:R:W236	7.87143	7	2	9
44	R:R:M237	5.1475	4	2	9
45	R:R:Y243	6.65	4	0	8
46	R:R:L259	5.374	5	0	5
47	R:R:Y262	5.04	5	0	7
48	R:R:W267	5.775	6	2	9
49	R:R:P270	4.682	5	8	9
50	R:R:R281	7.58333	6	2	7
51	R:R:F285	7.975	4	2	6
52	R:R:D287	4.642	5	2	3
53	R:R:W290	11.58	5	2	9
54	R:R:L298	5.54	4	2	6
55	R:R:I301	7.5325	4	2	7
56	R:R:H302	6.41	6	2	6
57	R:R:M327	7.35	4	0	7
58	R:R:I354	5.43	4	0	6
59	R:R:Q355	7.465	4	2	8
60	R:R:F356	7.59286	7	2	7
61	R:R:R362	7.364	5	0	4
62	R:R:Y372	8.7675	4	9	7
63	R:R:H377	7.096	5	3	7
64	R:R:H381	8.19	4	0	9
65	R:R:F382	4.63	4	0	7
66	R:R:Q383	8.8125	4	2	9
67	R:R:F385	8.5425	4	0	5
68	R:R:Y391	8.7425	4	0	8
69	R:R:F393	3.935	4	0	8
70	R:R:T401	2.945	4	0	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?33	R:R:W128	11.6909	5.64	Yes	Yes	1	0	5
2	R:R:S129	R:R:W82	22.3136	6.18	Yes	Yes	0	7	9
3	R:R:S91	R:R:W82	49.7144	3.71	No	Yes	0	5	9
4	R:R:S91	R:R:T85	48.0215	6.4	No	No	0	5	7
5	R:R:P86	R:R:T85	44.6112	5.25	No	No	6	2	7
6	R:R:P86	R:R:Y65	42.9335	6.95	No	No	0	2	3
7	L:L:?33	R:R:Y131	10.2386	5.8	Yes	Yes	1	0	5
8	R:R:F102	R:R:Y131	52.946	6.19	Yes	Yes	1	4	5
9	R:R:D101	R:R:F102	80.6927	3.58	Yes	Yes	1	4	4
10	R:R:D101	R:R:P100	87.169	3.22	Yes	Yes	1	4	4
11	L:L:K18	R:R:P100	98.8752	5.02	No	Yes	0	0	4
12	L:L:E15	L:L:K18	99.2448	5.4	No	No	0	0	0
13	L:L:E15	L:L:K11	99.6189	8.1	No	No	0	0	0
14	L:L:K11	R:R:R362	100	4.95	No	Yes	0	0	4
15	L:L:N3	R:R:R362	11.3855	7.23	No	Yes	0	0	4
16	L:L:N3	R:R:W361	10.2187	16.95	No	No	0	0	4
17	L:L:L4	R:R:W361	10.4821	3.42	No	No	0	0	4
18	L:L:L4	R:R:M306	10.5791	4.24	No	No	0	0	4
19	L:L:T6	R:R:M306	10.6944	6.02	Yes	No	0	0	4
20	L:L:T6	R:R:H302	27.0931	5.48	Yes	Yes	2	0	6
21	R:R:R362	R:R:Y372	63.9948	8.23	Yes	Yes	0	4	7
22	R:R:M376	R:R:Y372	64.3781	14.37	No	Yes	9	7	7
23	R:R:I380	R:R:M376	65.1348	4.37	No	No	0	6	7
24	R:R:F356	R:R:I380	65.2578	11.3	Yes	No	0	7	6
25	L:L:T6	R:R:F356	14.6874	6.49	Yes	Yes	2	0	7
26	R:R:D103	R:R:E106	12.1789	5.2	Yes	Yes	0	3	4
27	R:R:D103	R:R:K141	13.9673	2.77	Yes	No	0	3	3
28	L:L:L19	R:R:K141	15.0234	7.05	No	No	0	0	3
29	L:L:L19	R:R:L142	15.396	2.77	No	No	0	0	2
30	R:R:L142	R:R:Y146	15.7908	5.86	No	Yes	0	2	2
31	L:L:L16	R:R:Y146	15.7671	7.03	Yes	Yes	3	0	2
32	L:L:L12	L:L:L16	21.9226	5.54	No	Yes	3	0	0
33	L:L:L12	R:R:H377	22.1372	5.14	No	Yes	3	0	7
34	R:R:H377	R:R:H381	49.4479	9.55	Yes	Yes	0	7	9
35	L:L:L9	R:R:H381	24.7312	5.14	No	Yes	0	0	9
36	L:L:L9	R:R:I198	24.7358	5.71	No	Yes	0	0	7
37	R:R:H156	R:R:H381	25.1558	10.75	No	Yes	0	7	9
38	R:R:H156	R:R:I198	25.1695	13.26	No	Yes	0	7	7
39	R:R:H302	R:R:L298	12.8593	3.86	Yes	Yes	2	6	6
40	R:R:F356	R:R:Y234	12.0239	12.38	Yes	Yes	2	7	7
41	L:L:Y22	R:R:P100	15.5251	6.95	Yes	Yes	1	0	4
42	L:L:H17	L:L:Y22	10.8976	8.71	Yes	Yes	1	0	0
43	R:R:D84	R:R:Y65	36.1282	12.64	No	No	0	4	3
44	R:R:D84	R:R:R74	34.423	8.34	No	Yes	0	4	4
45	R:R:C81	R:R:R74	18.9995	2.79	No	Yes	4	9	4
46	R:R:C81	R:R:W76	17.2875	5.22	No	Yes	4	9	8
47	R:R:D83	R:R:R74	10.3905	10.72	No	Yes	0	5	4
48	R:R:K110	R:R:W82	10.389	32.49	Yes	Yes	0	8	9
49	R:R:V108	R:R:Y131	21.2316	12.62	Yes	Yes	1	7	5
50	R:R:C134	R:R:F102	21.9746	6.98	No	Yes	1	9	4
51	R:R:C134	R:R:V108	20.8734	3.42	No	Yes	1	9	7
52	R:R:F356	R:R:Q383	48.976	4.68	Yes	Yes	2	7	9
53	R:R:Q383	R:R:Y191	37.9654	13.53	Yes	Yes	2	9	8
54	R:R:L163	R:R:Y191	18.4497	5.86	Yes	Yes	2	8	8
55	R:R:F188	R:R:L163	16.8553	4.87	Yes	Yes	0	8	8
56	R:R:F188	R:R:S166	21.3881	7.93	Yes	No	0	8	9
57	R:R:I198	R:R:N194	42.3142	7.08	Yes	No	0	7	8
58	R:R:N194	R:R:N233	42.0492	9.54	No	Yes	0	8	9
59	R:R:N233	R:R:Y191	29.9444	18.61	Yes	Yes	2	9	8
60	R:R:V387	R:R:Y191	24.5983	5.05	No	Yes	0	9	8
61	R:R:F188	R:R:V387	17.6418	3.93	Yes	No	0	8	9
62	R:R:C392	R:R:S166	11.1633	3.44	No	No	0	9	9
63	R:R:F170	R:R:F188	12.8669	5.36	No	Yes	0	8	8
64	R:R:N233	R:R:T190	70.5787	7.31	Yes	No	2	9	9
65	R:R:T190	R:R:W236	51.15	6.06	No	Yes	2	9	9
66	R:R:L183	R:R:W236	19.6394	4.56	No	Yes	0	8	9
67	R:R:L259	R:R:Q179	15.0829	6.65	Yes	No	0	5	7
68	R:R:W236	R:R:Y263	10.3455	3.86	Yes	No	2	9	5
69	R:R:T190	R:R:W267	18.4986	4.85	No	Yes	2	9	9
70	R:R:M237	R:R:Y234	18.6872	3.59	Yes	Yes	2	9	7
71	R:R:M237	R:R:Q383	11.7727	6.8	Yes	Yes	2	9	9
72	R:R:M237	R:R:N233	23.9836	4.21	Yes	Yes	2	9	9
73	R:R:I301	R:R:T274	11.8475	6.08	Yes	No	0	7	6
74	R:R:C232	R:R:W267	15.2135	3.92	No	Yes	0	8	9
75	R:R:C232	R:R:P270	13.8741	7.53	No	Yes	0	8	9
76	R:R:C239	R:R:W236	21.4087	7.84	No	Yes	0	7	9
77	R:R:C239	R:R:Y262	17.4028	5.38	No	Yes	0	7	7
78	R:R:I242	R:R:Y262	12.9837	4.84	No	Yes	0	7	7
79	R:R:F315	R:R:I242	12.0445	3.77	No	No	0	8	7
80	R:R:K256	R:R:Q179	19.3431	2.71	No	No	0	5	7
81	R:R:K256	R:R:R258	12.9013	7.43	No	No	0	5	5
82	R:R:L298	R:R:R281	11.7429	3.64	Yes	Yes	2	6	7
83	R:R:D373	R:R:R362	28.5264	11.91	No	Yes	0	5	4
84	R:R:D373	R:R:H377	28.6676	3.78	No	Yes	0	5	7
85	R:R:V108	R:R:W82	40.8771	3.68	Yes	Yes	0	7	9
86	R:R:S129	R:R:Y131	21.0926	7.63	Yes	Yes	1	7	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
H:H:?1	R:R:W128	4.09	1	Yes	Yes	0	5	2	1
H:H:?1	R:R:N130	24.64	1	Yes	No	0	8	2	2
L:L:C1	R:R:L298	9.52	2	No	Yes	0	6	0	1
L:L:C1	R:R:H302	7.37	2	No	Yes	0	6	0	1
L:L:S2	R:R:E294	5.75	0	No	No	0	3	0	1
L:L:N3	R:R:W361	16.95	0	No	No	0	4	0	1
L:L:N3	R:R:R362	7.23	0	No	Yes	0	4	0	1
L:L:L4	R:R:M306	4.24	0	No	No	0	4	0	1
L:L:L4	R:R:W361	3.42	0	No	No	0	4	0	1
L:L:S5	R:R:F356	5.28	0	No	Yes	0	7	0	1
L:L:T6	R:R:Y234	7.49	2	Yes	Yes	0	7	0	1
L:L:T6	R:R:H302	5.48	2	Yes	Yes	0	6	0	1
L:L:T6	R:R:V305	4.76	2	Yes	No	0	7	0	1
L:L:T6	R:R:M306	6.02	2	Yes	No	0	4	0	1
L:L:T6	R:R:F356	6.49	2	Yes	Yes	0	7	0	1
L:L:C7	R:R:V293	3.42	2	No	No	0	6	0	1
L:L:C7	R:R:H302	8.85	2	No	Yes	0	6	0	1
L:L:V8	R:R:H377	4.15	0	No	Yes	0	7	0	1
L:L:L9	R:R:I198	5.71	0	No	Yes	0	7	0	1
L:L:L9	R:R:H381	5.14	0	No	Yes	0	9	0	1
L:L:K11	R:R:R362	4.95	0	No	Yes	0	4	0	1
L:L:L12	R:R:L148	4.15	3	No	No	0	5	0	1
L:L:L12	R:R:H377	5.14	3	No	Yes	0	7	0	1
L:L:S13	R:R:V206	4.85	0	No	No	0	3	0	1
L:L:Q14	R:R:V293	10.03	0	No	No	0	6	0	1
L:L:Q14	R:R:E294	10.19	0	No	No	0	3	0	1
L:L:L16	R:R:Y146	7.03	3	Yes	Yes	0	2	0	1
L:L:L16	R:R:Y149	4.69	3	Yes	Yes	0	5	0	1
L:L:H17	R:R:V212	9.69	1	Yes	No	0	3	0	1
L:L:H17	R:R:L291	7.71	1	Yes	No	0	6	0	1
L:L:K18	R:R:P100	5.02	0	No	Yes	0	4	0	1
L:L:L19	R:R:K141	7.05	0	No	No	0	3	0	1
L:L:Q20	R:R:Y146	6.76	0	No	Yes	0	2	0	1
L:L:T21	R:R:G209	3.64	1	No	No	0	3	0	1
L:L:Y22	R:R:P38	5.56	1	Yes	No	0	5	0	1
L:L:Y22	R:R:L40	5.86	1	Yes	No	0	5	0	1
L:L:Y22	R:R:Y41	5.96	1	Yes	Yes	0	3	0	1
L:L:Y22	R:R:P100	6.95	1	Yes	Yes	0	4	0	1
L:L:R24	R:R:N135	3.62	1	No	Yes	0	3	0	1
L:L:T25	R:R:W79	3.64	1	Yes	Yes	0	6	0	1
L:L:T25	R:R:F99	3.89	1	Yes	Yes	0	5	0	1
L:L:T25	R:R:D101	8.67	1	Yes	Yes	0	4	0	1
L:L:T25	R:R:F102	7.78	1	Yes	Yes	0	4	0	1
L:L:T27	R:R:N135	4.39	1	No	Yes	0	3	0	1
L:L:G28	R:R:W128	4.22	0	No	Yes	0	5	0	1
L:L:S29	R:R:H121	11.16	1	No	Yes	0	4	0	1
L:L:S29	R:R:E123	5.75	1	No	No	0	4	0	1
L:L:S29	R:R:N124	8.94	1	No	No	0	5	0	1
L:L:G30	R:R:R126	4.5	0	No	No	0	4	0	1
L:L:P32	R:R:D77	9.66	1	No	Yes	0	9	0	1
L:L:P32	R:R:W79	21.62	1	No	Yes	0	6	0	1
L:L:?33	R:R:D77	10.08	1	Yes	Yes	0	9	0	1
L:L:?33	R:R:W128	5.64	1	Yes	Yes	0	5	0	1
L:L:?33	R:R:S129	7.43	1	Yes	Yes	0	7	0	1
L:L:?33	R:R:Y131	5.8	1	Yes	Yes	0	5	0	1
R:R:P38	R:R:Y41	5.56	1	No	Yes	5	3	1	1
R:R:P100	R:R:Y41	9.74	1	Yes	Yes	4	3	1	1
R:R:D77	R:R:S129	7.36	1	Yes	Yes	9	7	1	1
R:R:D77	R:R:Y131	5.75	1	Yes	Yes	9	5	1	1
R:R:F99	R:R:W79	13.03	1	Yes	Yes	5	6	1	1
R:R:F102	R:R:W79	5.01	1	Yes	Yes	4	6	1	1
R:R:W79	R:R:Y131	15.43	1	Yes	Yes	6	5	1	1
R:R:L80	R:R:P96	14.78	1	No	Yes	5	9	2	2
R:R:L80	R:R:Y131	7.03	1	No	Yes	5	5	2	1
R:R:V108	R:R:W82	3.68	1	Yes	Yes	7	9	2	2
R:R:S129	R:R:W82	6.18	1	Yes	Yes	7	9	1	2
R:R:P96	R:R:Y98	8.34	1	Yes	No	9	4	2	2
R:R:F102	R:R:P96	5.78	1	Yes	Yes	4	9	1	2
R:R:P96	R:R:Y131	4.17	1	Yes	Yes	9	5	2	1
R:R:F99	R:R:Y98	5.16	1	Yes	No	5	4	1	2
R:R:F102	R:R:F99	18.22	1	Yes	Yes	4	5	1	1
R:R:D101	R:R:P100	3.22	1	Yes	Yes	4	4	1	1
R:R:D101	R:R:F102	3.58	1	Yes	Yes	4	4	1	1
R:R:D101	R:R:N135	9.42	1	Yes	Yes	4	3	1	1
R:R:F102	R:R:Y131	6.19	1	Yes	Yes	4	5	1	1
R:R:C134	R:R:F102	6.98	1	No	Yes	9	4	2	1
R:R:F102	R:R:N135	10.87	1	Yes	Yes	4	3	1	1
R:R:V108	R:R:Y131	12.62	1	Yes	Yes	7	5	2	1
R:R:C134	R:R:V108	3.42	1	No	Yes	9	7	2	2
R:R:H121	R:R:P122	9.15	1	Yes	No	4	5	1	2
R:R:E123	R:R:H121	9.85	1	No	Yes	4	4	1	1
R:R:H121	R:R:W128	11.64	1	Yes	Yes	4	5	1	1
R:R:N124	R:R:R126	22.9	0	No	No	5	4	1	1
R:R:N130	R:R:W128	5.65	1	No	Yes	8	5	2	1
R:R:S129	R:R:Y131	7.63	1	Yes	Yes	7	5	1	1
R:R:L142	R:R:Y146	5.86	0	No	Yes	2	2	1	1
R:R:Y146	R:R:Y149	3.97	3	Yes	Yes	2	5	1	1
R:R:L148	R:R:Y374	4.69	3	No	No	5	6	1	2
R:R:H377	R:R:L148	12.86	3	Yes	No	7	5	1	1
R:R:Y149	R:R:Y150	8.94	3	Yes	No	5	4	1	2
R:R:I153	R:R:Y149	6.04	3	No	Yes	7	5	2	1
R:R:L202	R:R:Y149	7.03	0	No	Yes	7	5	2	1
R:R:A152	R:R:H381	7.32	0	No	Yes	7	9	2	1
R:R:H156	R:R:I198	13.26	0	No	Yes	7	7	2	1
R:R:H156	R:R:H381	10.75	0	No	Yes	7	9	2	1
R:R:I198	R:R:N194	7.08	0	Yes	No	7	8	1	2
R:R:H226	R:R:I198	3.98	0	No	Yes	6	7	2	1
R:R:P207	R:R:V206	3.53	0	No	No	3	3	2	1
R:R:C289	R:R:V212	8.54	0	No	No	9	3	2	1
R:R:L291	R:R:V212	4.47	1	No	No	6	3	1	1
R:R:H226	R:R:Q227	3.71	0	No	Yes	6	7	2	2
R:R:H226	R:R:M230	3.94	0	No	No	6	6	2	2
R:R:I301	R:R:Q227	5.49	2	Yes	Yes	7	7	2	2
R:R:H302	R:R:Q227	4.95	2	Yes	Yes	6	7	1	2
R:R:M230	R:R:Y234	7.18	0	No	Yes	6	7	2	1
R:R:M237	R:R:Y234	3.59	2	Yes	Yes	9	7	2	1
R:R:V305	R:R:Y234	10.09	2	No	Yes	7	7	1	1
R:R:F356	R:R:Y234	12.38	2	Yes	Yes	7	7	1	1
R:R:M237	R:R:Q383	6.8	2	Yes	Yes	9	9	2	2
R:R:H277	R:R:R281	12.41	2	No	Yes	7	7	2	2
R:R:H277	R:R:L298	5.14	2	No	Yes	7	6	2	1
R:R:H277	R:R:I301	10.61	2	No	Yes	7	7	2	2
R:R:L298	R:R:R281	3.64	2	Yes	Yes	6	7	1	2
R:R:H302	R:R:L298	3.86	2	Yes	Yes	6	6	1	1
R:R:H302	R:R:I301	7.95	2	Yes	Yes	6	7	1	2
R:R:F356	R:R:L309	3.65	2	Yes	No	7	7	1	2
R:R:F356	R:R:Q355	9.37	2	Yes	Yes	7	8	1	2
R:R:Q355	R:R:Q383	10.24	2	Yes	Yes	8	9	2	2
R:R:F356	R:R:I380	11.3	2	Yes	No	7	6	1	2
R:R:F356	R:R:Q383	4.68	2	Yes	Yes	7	9	1	2
R:R:G369	R:R:R362	4.5	0	No	Yes	4	4	2	1
R:R:R362	R:R:Y372	8.23	0	Yes	Yes	4	7	1	2
R:R:D373	R:R:R362	11.91	0	No	Yes	5	4	2	1
R:R:D373	R:R:H377	3.78	0	No	Yes	5	7	2	1
R:R:H377	R:R:H381	9.55	3	Yes	Yes	7	9	1	1
L:L:L16	R:R:A145	3.15	3	Yes	No	0	4	0	1
R:R:K141	R:R:T138	3	0	No	No	3	2	1	2
R:R:L291	R:R:V205	2.98	1	No	No	6	7	1	2
L:L:P23	R:R:Y41	2.78	0	No	Yes	0	3	0	1
R:R:P207	R:R:Y149	2.78	0	No	Yes	3	5	2	1
L:L:L19	R:R:L142	2.77	0	No	No	0	2	0	1
R:R:D103	R:R:K141	2.77	0	Yes	No	3	3	2	1
R:R:V203	R:R:Y149	2.52	0	No	Yes	3	5	2	1
L:L:T31	R:R:W79	2.43	0	No	Yes	0	6	0	1
R:R:W361	R:R:Y299	1.93	0	No	No	4	7	1	2
L:L:G10	R:R:V293	1.84	0	No	No	0	6	0	1
L:L:S5	R:R:P360	1.78	0	No	No	0	5	0	1
R:R:K37	R:R:P38	1.67	0	No	No	4	5	2	1
R:R:R45	R:R:Y41	1.03	0	No	Yes	7	3	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	7TYN_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.22
Number of Linked Nodes	389
Number of Links	465
Number of Hubs	70
Number of Links mediated by Hubs	258
Number of Communities	9
Number of Nodes involved in Communities	94
Number of Links involved in Communities	139

Path Summary
Number Of Nodes in MetaPath	87
Number Of Links MetaPath	86
Number of Shortest Paths	232710
Length Of Smallest Path	3
Average Path Length	20.0424
Length of Longest Path	39
Minimum Path Strength	1.19
Average Path Strength	6.80409
Maximum Path Strength	21.175
Minimum Path Correlation	0.7
Average Path Correlation	0.953683
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	3.22581
Average % Of Corr. Nodes	49.8839
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	48.4936
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain • G protein-coupled receptor-like
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	NAG
PDB Residues	H:H:?1 H:H:?2
Environment Details	Open EMBL-EBI Page
Code	NAG
Name	N-Acetylglucosamine
Synonyms	N-Acetylglucosamine
Identifier
Formula	C8 H15 N O6
Molecular Weight	221.208
SMILES
PubChem	24139
Formal Charge	0
Total Atoms	30
Total Chiral Atoms	5
Total Bonds	30
Total Aromatic Bonds	0


Code	NH2
PDB Residues	L:L:?33
Environment Details	Open EMBL-EBI Page
Code	NH2
Name	AMINO GROUP
Synonyms
Identifier
Formula	H2 N
Molecular Weight	16.023
SMILES
PubChem	123329
Formal Charge	0
Total Atoms	3
Total Chiral Atoms	0
Total Bonds	2
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P30988
Sequence	>7TYN_nogp_Chain_R K P F L Y V V G R K K M M D A Q Y K C Y D R M Q Q L P A Y Q G E G P Y C N R T W D G W L C W D D T P A G V L S Y Q F C P D Y F P D F D P S E K V T K Y C D E K G V W F K H P E N N R T W S N Y T M C N A F T P E K L K N A Y V L Y Y L A I V G H S L S I F T L V I S L G I F V F F R S L G C Q R V T L H K N M F L T Y I L N S M I I I I H L V E V V P N G E L V R R D P V S C K I L H F F H Q Y M M A C N Y F W M L C E G I Y L H T L I V V A V F T E K Q R L R W Y Y L L G W G F P L V P T T I H A I T R A V Y F N D N C W L S V E T H L L Y I I H G P V M A A L V V N F F F L L N I V R V L V T K M R E T H E A E S H M Y L K A V K A T M I L V P L L G I Q F V V F P W R P S N K M L G K I Y D Y V M H S L I H F Q G F F V A T I Y C F C N N E V Q T T V K R Q W A Q F Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7X5H	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	Gi1/β1/γ2	3.1	2022-09-14	doi.org/10.1038/s41421-022-00412-3
	7X5H (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-		3.1	2022-09-14	doi.org/10.1038/s41421-022-00412-3
	7UM5	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-	chim(NtGi1-Go)/β1/γ2	2.73	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7UM5 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_5A	Homo sapiens	5-CT	-		2.73	2022-07-20	doi.org/10.1038/s41594-022-00796-6
	7XTC	A	Amine	5-Hydroxytryptamine	5-HT₇	Homo sapiens	5-CT	-	Gs/β1/γ2	3.2	2022-07-27	doi.org/10.1016/j.molcel.2022.05.031
	7XTC (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT₇	Homo sapiens	5-CT	-		3.2	2022-07-27	doi.org/10.1016/j.molcel.2022.05.031
	6E67	A	Amine	Adrenergic	β₂	Homo sapiens	BI167107	-	Gs(CT)	3.7	2019-06-05	doi.org/10.1016/j.cell.2019.04.021
	6NIY	B1	Peptide	Calcitonin	CT	Homo sapiens	Adrenomedullin	-	Gs/β1/γ2	3.34	2019-01-23	doi.org/10.1021/acsptsci.8b00056
	6NIY (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Adrenomedullin	-		3.34	2019-01-23	doi.org/10.1021/acsptsci.8b00056
	5UZ7	B1	Peptide	Calcitonin	CT	Homo sapiens	-	-	Gs/β1/γ2	4.1	2017-05-03	doi.org/10.1038/nature22327
	5UZ7 (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	-	-		4.1	2017-05-03	doi.org/10.1038/nature22327
	8F0J	B1	Peptide	Calcitonin	CT	Homo sapiens	Pramlintide Analogue San45	-	Gs/β1/γ2	2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F0J (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Pramlintide Analogue San45	-		2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	7TYL	B1	Peptide	Calcitonin	CT	Homo sapiens	Amylin	-	Gs/β1/γ2	3.3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYL (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Amylin	-		3.3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYO	B1	Peptide	Calcitonin	CT	Homo sapiens	Calcitonin	-	Gs/β1/γ2	2.7	2022-03-23	doi.org/10.1126/science.abm9609
	7TYO (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Calcitonin	-		2.7	2022-03-23	doi.org/10.1126/science.abm9609
	7TYI	B1	Peptide	Calcitonin	CT	Homo sapiens	Amylin	-	Gs/β1/γ2	3.3	2022-03-30	doi.org/10.1126/science.abm9609
	7TYI (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Amylin	-		3.3	2022-03-30	doi.org/10.1126/science.abm9609
	7TYN	B1	Peptide	Calcitonin	CT	Homo sapiens	Calcitonin-1	-	Gs/β1/γ2	2.6	2022-03-30	doi.org/10.1126/science.abm9609
	7TYN (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Calcitonin-1	-		2.6	2022-03-30	doi.org/10.1126/science.abm9609
	9BUB	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-	Gs/β1/γ2	2.3	2025-04-23	doi.org/10.1038/s41467-025-58680-y
	9BUB (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-		2.3	2025-04-23	doi.org/10.1038/s41467-025-58680-y
	9BLB	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide backbone (non-acylated)	-	Gs/β1/γ2	3.2	2025-04-16	To be published
	9BLB (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide backbone (non-acylated)	-		3.2	2025-04-16	To be published
	9BLC	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide backbone (non-acylated)	-	Gs/β1/γ2	3.3	2025-04-16	To be published
	9BLC (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide backbone (non-acylated)	-		3.3	2025-04-16	To be published
	9BUE	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-	Gs/β1/γ2	3.6	2025-04-16	To be published
	9BUE (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-		3.6	2025-04-16	To be published
	9BUC	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-	Gs/β1/γ2	3.4	2025-04-23	To be published
	9BUC (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-		3.4	2025-04-23	To be published
	9BUD	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-	Gs/β1/γ2	2.5	2025-04-23	To be published
	9BUD (No Gprot)	B1	Peptide	Calcitonin	CT	Homo sapiens	Cagrilintide	-		2.5	2025-04-23	To be published
	9AUC	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin gene-related peptide-1	-	Gs/β1/γ2; RAMP1	2.4	2024-04-24	doi.org/10.1021/acs.biochem.4c00114
	9AUC (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin gene-related peptide-1	-		2.4	2024-04-24	doi.org/10.1021/acs.biochem.4c00114
	7TYF	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Amylin	-	Gs/β1/γ2; RAMP1	2.2	2022-03-23	doi.org/10.1126/science.abm9609
	7TYF (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Amylin	-		2.2	2022-03-23	doi.org/10.1126/science.abm9609
	7TYW	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin-1	-	Gs/β1/γ2; RAMP1	3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYW (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Calcitonin-1	-		3	2022-03-23	doi.org/10.1126/science.abm9609
	9BLW	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide backbone (non-acylated)	-	Gs/β1/γ2; RAMP1	3.2	2025-04-16	To be published
	9BLW (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide backbone (non-acylated)	-		3.2	2025-04-16	To be published
	9BP3	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide	-	Gs/β1/γ2; RAMP1	2.2	2025-04-23	To be published
	9BP3 (No Gprot)	B1	Peptide	Calcitonin	CT (AMY1)	Homo sapiens	Cagrilintide	-		2.2	2025-04-23	To be published
	7TYH	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-	Gs/β1/γ2; RAMP2	3.3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYH (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-		3.3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYY	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-	Gs/β1/γ2; RAMP2	3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYY (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Calcitonin-1	-		3	2022-03-23	doi.org/10.1126/science.abm9609
	7TYX	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Amylin	-	Gs/β1/γ2; RAMP2	2.55	2022-03-30	doi.org/10.1126/science.abm9609
	7TYX (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Amylin	-		2.55	2022-03-30	doi.org/10.1126/science.abm9609
	9BQ3	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Cagrilintide	-	Gs/β1/γ2; RAMP2	2.8	2025-04-23	To be published
	9BQ3 (No Gprot)	B1	Peptide	Calcitonin	CT (AMY2)	Homo sapiens	Cagrilintide	-		2.8	2025-04-23	To be published
	8F0K	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-	Gs/β1/γ2; RAMP3	1.9	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F0K (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-		1.9	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2A	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-	Gs/β1/γ2; RAMP3	2.2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2A (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San385	-		2.2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2B	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San45	-	Gs/β1/γ2; RAMP3	2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	8F2B (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Pramlintide Analogue San45	-		2	2023-08-02	doi.org/10.1038/s41589-023-01393-4
	7TZF	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Amylin	-	Gs/β1/γ2; RAMP3	2.4	2022-03-23	doi.org/10.1126/science.abm9609
	7TZF (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Amylin	-		2.4	2022-03-23	doi.org/10.1126/science.abm9609
	9BTW	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Cagrilintide	-	Gs/β1/γ2; RAMP3	3	2025-04-16	To be published
	9BTW (No Gprot)	B1	Peptide	Calcitonin	CT (AMY3)	Homo sapiens	Cagrilintide	-		3	2025-04-16	To be published
	6E3Y	B1	Peptide	Calcitonin	CT Like	Homo sapiens	Calcitonin gene-related peptide-1	-	Gs/β1/γ2; RAMP1	3.3	2018-09-19	doi.org/10.1038/s41586-018-0535-y
	6E3Y (No Gprot)	B1	Peptide	Calcitonin	CT Like	Homo sapiens	Calcitonin gene-related peptide-1	-		3.3	2018-09-19	doi.org/10.1038/s41586-018-0535-y
	7KNT	B1	Peptide	Calcitonin	CT Like	Homo sapiens	-	-	RAMP1	3.15	2021-02-24	doi.org/10.1126/science.abf7258
	7KNU	B1	Peptide	Calcitonin	CT Like	Homo sapiens	Calcitonin gene-related peptide-1	-	RAMP1	3.49	2021-02-24	doi.org/10.1126/science.abf7258
	6UUN	B1	Peptide	Calcitonin	CT Like (AM1)	Homo sapiens	Adrenomedullin	-	Gs/β1/γ2; RAMP2	3	2020-03-25	doi.org/10.1021/acsptsci.9b00080
	6UUN (No Gprot)	B1	Peptide	Calcitonin	CT Like (AM1)	Homo sapiens	Adrenomedullin	-		3	2020-03-25	doi.org/10.1021/acsptsci.9b00080
	6UUS	B1	Peptide	Calcitonin	CT Like (AM2)	Homo sapiens	Adrenomedullin	-	Gs/β1/γ2; RAMP3	2.4	2020-04-01	doi.org/10.1021/acsptsci.9b00080
	6UUS (No Gprot)	B1	Peptide	Calcitonin	CT Like (AM2)	Homo sapiens	Adrenomedullin	-		2.4	2020-04-01	doi.org/10.1021/acsptsci.9b00080
	6UVA	B1	Peptide	Calcitonin	CT Like (AM2)	Homo sapiens	Adrenomedullin-2	-	Gs/β1/γ2; RAMP3	2.3	2020-04-01	doi.org/10.1021/acsptsci.9b00080
	6UVA (No Gprot)	B1	Peptide	Calcitonin	CT Like (AM2)	Homo sapiens	Adrenomedullin-2	-		2.3	2020-04-01	doi.org/10.1021/acsptsci.9b00080
	6PH7	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Nerol	Gt(CT)	2.9	2020-07-01	To be published
	6PGS	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Geraniol	Gt(CT)	2.9	2020-07-01	To be published
	6PEL	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	Citronellol	Gt(CT)	3.19	2020-06-24	To be published
	4J4Q	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl β-D-Glucopyranoside	-	Gt(CT)	2.65	2013-10-30	doi.org/10.1002/anie.201302374
	4X1H	A	Sensory	Opsins	Rhodopsin	Bos taurus	Nonyl-β-D-Glucopyranoside	-	Gt(CT)	2.29	2015-11-04	doi.org/10.1016/j.str.2015.09.015
	4BEY	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	2.9	2013-05-08	doi.org/10.1038/embor.2013.44
	3DQB	A	Sensory	Opsins	Rhodopsin	Bos taurus	-	-	Gt(CT)	3.2	2008-09-23	doi.org/10.1038/nature07330
	3PQR	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.85	2011-03-09	doi.org/10.1038/nature09789
	2X72	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3	2011-03-16	doi.org/10.1038/nature09795
	5WKT	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	3.2	2017-12-13	doi.org/10.1038/nprot.2017.135
	4A4M	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	3.3	2012-01-25	doi.org/10.1073/pnas.1114089108
	5EN0	A	Sensory	Opsins	Rhodopsin	Bos taurus	All-trans-Retinal	-	Gt(CT)	2.81	2016-08-10	doi.org/10.15252/embr.201642671
	6NWE	A	Sensory	Opsins	Rhodopsin	Bos taurus	Octyl-β-D-Glucopyranoside	-	Gt(CT)	2.71	2020-02-12	To be published
	6TP4	A	Peptide	Orexin	OX₁	Homo sapiens	ACT-462206	-	-	3.01	2020-01-01	doi.org/10.1021/acs.jmedchem.9b01787

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7TYN_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.