Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1L:L:T7 6.028520
2L:L:R18 6.055440
3L:L:F24 8.22540
4L:L:S35 3.552500
5L:L:P38 9.776510
6L:L:?39 6.8425410
7R:R:W76 7.0575418
8R:R:D77 5.97833619
9R:R:W79 13.678516
10R:R:W82 7.848519
11R:R:P96 7.9875409
12R:R:Y98 5.8425404
13R:R:F102 5.80167614
14R:R:E106 6.735404
15R:R:K110 10.79418
16R:R:C112 5.4025419
17R:R:W118 7.128519
18R:R:S129 8.05517
19R:R:Y131 10.4733615
20R:R:F137 5.228501
21R:R:T138 4.9475402
22R:R:Y149 5.6575405
23R:R:H156 7.8625407
24R:R:L163 5.1825408
25R:R:F170 5.2275408
26R:R:F173 5.05333677
27R:R:L176 4.8725479
28R:R:Q179 7.415407
29R:R:L183 3.946538
30R:R:H184 8.09409
31R:R:F188 5.5275408
32R:R:Y191 6.20286728
33R:R:I198 6.46407
34R:R:F224 3.23405
35R:R:N233 7.31429
36R:R:Y234 6.976527
37R:R:F235 5.215455
38R:R:W236 7.41143739
39R:R:M237 5.5375429
40R:R:E240 8.105409
41R:R:Y243 7.334538
42R:R:I248 3.71487
43R:R:Y262 6.25437
44R:R:P270 4.682559
45R:R:H277 7.196527
46R:R:F285 8.26406
47R:R:W290 7.824509
48R:R:L291 4.966546
49R:R:I301 6.54427
50R:R:H302 5.81286726
51R:R:M327 4.3625407
52R:R:I354 6.0575406
53R:R:Q355 7.1325428
54R:R:F356 6.98833627
55R:R:P363 3.74407
56R:R:Y372 7.0125407
57R:R:M376 3.5625407
58R:R:H381 6.74409
59R:R:F382 4.635407
60R:R:Q383 7.755429
61R:R:F385 7.38405
62R:R:C392 4.985469
63R:R:T401 3.57477
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1L:L:?102 R:R:H296 10.64064.16NoNo002
2R:R:H296 R:R:L297 12.76285.14NoNo024
3R:R:F285 R:R:S292 10.62436.61YesNo064
4R:R:L297 R:R:T280 16.876311.79NoNo044
5R:R:H277 R:R:T280 27.35934.11YesNo074
6R:R:H277 R:R:L298 30.82915.14YesNo276
7R:R:H302 R:R:L298 31.65499YesNo266
8R:R:H277 R:R:I301 30.970310.61YesYes277
9R:R:H302 R:R:I301 84.85813.98YesYes267
10L:L:T7 R:R:H302 72.64275.48YesYes206
11L:L:T7 R:R:Y234 47.88458.74YesYes207
12R:R:H302 R:R:M230 46.42125.25YesNo266
13R:R:M230 R:R:Y234 47.14577.18NoYes267
14L:L:T7 R:R:F356 26.86925.19YesYes207
15R:R:F356 R:R:I380 15.23097.54YesNo076
16R:R:I380 R:R:M376 14.40215.83NoYes067
17R:R:M237 R:R:Y234 1003.59YesYes297
18R:R:M237 R:R:N233 54.65.61YesYes299
19R:R:N194 R:R:N233 82.23664.09NoYes089
20R:R:I198 R:R:N194 81.88977.08YesNo078
21R:R:H156 R:R:I198 11.238211.93YesYes077
22R:R:H223 R:R:Q227 42.98629.89NoNo057
23R:R:H223 R:R:L291 36.31983.86NoYes056
24L:L:R18 R:R:L291 14.15246.07YesYes406
25R:R:I198 R:R:L202 73.55032.85YesNo077
26R:R:L202 R:R:Y149 73.15234.69NoYes075
27L:L:L17 R:R:Y149 72.36853.52NoYes005
28L:L:L17 L:L:S20 71.95823NoNo000
29L:L:S20 R:R:F137 71.54583.96NoYes001
30L:L:F24 L:L:R18 10.90673.21YesYes400
31R:R:C289 R:R:L291 14.16573.17NoYes096
32R:R:C219 R:R:C289 12.00877.28NoNo099
33R:R:C219 R:R:P216 10.92723.77NoNo094
34R:R:D101 R:R:F137 64.22259.55NoYes041
35L:L:T31 R:R:D101 63.77334.34NoNo004
36L:L:T31 R:R:F99 22.039518.16NoNo105
37L:L:T31 R:R:F102 41.27437.78NoYes104
38R:R:F99 R:R:W79 21.51669.02NoYes156
39R:R:F102 R:R:W79 22.34654.01YesYes146
40L:L:V33 R:R:F102 13.02272.62NoYes004
41L:L:V33 R:R:T132 12.44153.17NoNo006
42R:R:N130 R:R:T132 11.83898.77NoNo086
43L:L:P38 R:R:W79 12.772132.43YesYes106
44R:R:W79 R:R:Y131 27.789119.29YesYes165
45R:R:S129 R:R:Y131 18.77337.63YesYes175
46R:R:K110 R:R:S129 15.47959.18YesYes187
47R:R:K110 R:R:W118 13.269315.08YesYes189
48R:R:M237 R:R:Y191 49.65884.79YesYes298
49R:R:L163 R:R:Y191 33.0695.86YesYes088
50R:R:F188 R:R:L163 31.47996.09YesYes088
51R:R:F170 R:R:F188 57.10186.43YesYes088
52R:R:C392 R:R:F170 49.57085.59YesYes098
53R:R:C392 R:R:S166 17.27846.89YesNo699
54R:R:A388 R:R:S166 15.99833.42NoNo089
55R:R:A388 R:R:T162 14.67633.36NoNo086
56R:R:F385 R:R:T162 13.35227.78YesNo056
57R:R:F356 R:R:Q383 34.54965.86YesYes279
58R:R:Q383 R:R:Y191 32.85516.76YesYes298
59R:R:V387 R:R:Y191 30.27457.57NoYes098
60R:R:F188 R:R:V387 29.7653.93YesNo089
61R:R:C392 R:R:I169 27.72263.27YesNo098
62R:R:F173 R:R:I169 26.4192.51YesNo078
63R:R:M187 R:R:Y191 41.96914.79NoYes088
64R:R:L183 R:R:W236 11.67923.42YesYes389
65R:R:E240 R:R:M187 33.50810.83YesNo098
66R:R:F188 R:R:H184 12.53575.66YesYes089
67R:R:E240 R:R:L351 26.54385.3YesNo099
68R:R:H277 R:R:R281 33.020912.41YesNo077
69R:R:R281 R:R:W290 12.913.99NoYes079
70R:R:F285 R:R:R281 18.945210.69YesNo067
71R:R:I301 R:R:T274 10.99886.08YesNo076
72R:R:L351 R:R:L352 25.64134.15NoNo099
73R:R:L352 R:R:N312 14.95875.49NoNo099
74R:R:L238 R:R:N312 13.49965.49NoNo089
75R:R:I242 R:R:L238 12.03235.71NoNo078
76R:R:F315 R:R:I242 11.29555.02NoNo087
77R:R:I354 R:R:L352 10.55674.28YesNo069
78R:R:M376 R:R:Y372 10.22733.59YesYes077
79R:R:I301 R:R:Q227 43.44165.49YesNo277
80R:R:N233 R:R:Y191 30.01779.3YesYes298
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
L:L:K2 R:R:E294 4.05 0 No No 0 3 0 1
L:L:C3 R:R:L298 3.17 2 No No 0 6 0 1
L:L:C3 R:R:H302 4.42 2 No Yes 0 6 0 1
L:L:T7 R:R:Y234 8.74 2 Yes Yes 0 7 0 1
L:L:T7 R:R:H302 5.48 2 Yes Yes 0 6 0 1
L:L:T7 R:R:M306 6.02 2 Yes No 0 4 0 1
L:L:T7 R:R:F356 5.19 2 Yes Yes 0 7 0 1
L:L:C8 R:R:H302 8.85 2 No Yes 0 6 0 1
L:L:A9 R:R:M376 3.22 0 No Yes 0 7 0 1
L:L:T10 R:R:H381 4.11 0 No Yes 0 9 0 1
L:L:Q11 R:R:M230 4.08 2 No No 0 6 0 1
L:L:Q11 R:R:H302 3.71 2 No Yes 0 6 0 1
L:L:R12 R:R:V293 3.92 0 No No 0 6 0 1
L:L:L13 R:R:H377 6.43 0 No No 0 7 0 1
L:L:E15 R:R:L291 5.3 4 No Yes 0 6 0 1
L:L:F16 R:R:F137 5.36 0 No Yes 0 1 0 1
L:L:L17 R:R:Y149 3.52 0 No Yes 0 5 0 1
L:L:R18 R:R:L291 6.07 4 Yes Yes 0 6 0 1
L:L:H19 R:R:P100 7.63 4 No No 0 4 0 1
L:L:S20 R:R:F137 3.96 0 No Yes 0 1 0 1
L:L:N22 R:R:G209 3.39 0 No No 0 3 0 1
L:L:N23 R:R:P100 3.26 0 No No 0 4 0 1
L:L:F24 R:R:L40 8.53 4 Yes No 0 5 0 1
L:L:P26 R:R:R213 8.65 0 No No 0 2 0 1
L:L:T31 R:R:F99 18.16 1 No No 0 5 0 1
L:L:T31 R:R:D101 4.34 1 No No 0 4 0 1
L:L:T31 R:R:F102 7.78 1 No Yes 0 4 0 1
L:L:V33 R:R:T132 3.17 0 No No 0 6 0 1
L:L:S35 R:R:H121 5.58 0 Yes No 0 4 0 1
L:L:S35 R:R:N124 5.96 0 Yes No 0 5 0 1
L:L:T37 R:R:W79 3.64 1 No Yes 0 6 0 1
L:L:P38 R:R:D77 4.83 1 Yes Yes 0 9 0 1
L:L:P38 R:R:G78 4.06 1 Yes No 0 5 0 1
L:L:P38 R:R:W79 32.43 1 Yes Yes 0 6 0 1
L:L:?39 R:R:D77 10.08 1 Yes Yes 0 9 0 1
L:L:?39 R:R:S129 7.43 1 Yes Yes 0 7 0 1
L:L:?39 R:R:Y131 5.8 1 Yes Yes 0 5 0 1
L:L:?102 R:R:H296 4.16 0 No No 0 2 0 1
L:L:?102 R:R:Y299 18.97 0 No No 0 7 0 1
R:R:G78 R:R:W76 4.22 1 No Yes 5 8 1 2
R:R:D77 R:R:G78 3.35 1 Yes No 9 5 1 1
R:R:D77 R:R:W82 3.35 1 Yes Yes 9 9 1 2
R:R:D77 R:R:S129 7.36 1 Yes Yes 9 7 1 1
R:R:D77 R:R:Y131 6.9 1 Yes Yes 9 5 1 1
R:R:F99 R:R:W79 9.02 1 No Yes 5 6 1 1
R:R:F102 R:R:W79 4.01 1 Yes Yes 4 6 1 1
R:R:W79 R:R:Y131 19.29 1 Yes Yes 6 5 1 1
R:R:V108 R:R:W82 6.13 0 No Yes 7 9 2 2
R:R:K110 R:R:W82 17.4 1 Yes Yes 8 9 2 2
R:R:S129 R:R:W82 8.65 1 Yes Yes 7 9 1 2
R:R:C95 R:R:P96 3.77 1 No Yes 9 9 2 2
R:R:C95 R:R:F102 5.59 1 No Yes 9 4 2 1
R:R:C134 R:R:C95 7.28 1 No No 9 9 2 2
R:R:P96 R:R:Y131 5.56 0 Yes Yes 9 5 2 1
R:R:F102 R:R:F99 6.43 1 Yes No 4 5 1 1
R:R:D101 R:R:F137 9.55 0 No Yes 4 1 1 1
R:R:C134 R:R:F102 8.38 1 No Yes 9 4 2 1
R:R:V108 R:R:Y131 17.66 0 No Yes 7 5 2 1
R:R:K110 R:R:S129 9.18 1 Yes Yes 8 7 2 1
R:R:H121 R:R:P122 4.58 0 No No 4 5 1 2
R:R:H121 R:R:W128 34.91 0 No No 4 5 1 2
R:R:N130 R:R:W128 11.3 0 No No 8 5 2 2
R:R:S129 R:R:Y131 7.63 1 Yes Yes 7 5 1 1
R:R:N130 R:R:T132 8.77 0 No No 8 6 2 1
R:R:F137 R:R:N135 3.62 0 Yes No 1 3 1 2
R:R:F137 R:R:L142 3.65 0 Yes No 1 2 1 2
R:R:H377 R:R:L148 19.28 0 No No 7 5 1 2
R:R:Y149 R:R:Y150 5.96 0 Yes No 5 4 1 2
R:R:I153 R:R:Y149 8.46 0 No Yes 7 5 2 1
R:R:L202 R:R:Y149 4.69 0 No Yes 7 5 2 1
R:R:A152 R:R:H381 7.32 0 No Yes 7 9 2 1
R:R:H156 R:R:H381 7.17 0 Yes Yes 7 9 2 1
R:R:H201 R:R:L291 6.43 0 No Yes 6 6 2 1
R:R:P207 R:R:V206 3.53 0 No No 3 3 2 1
R:R:H223 R:R:L291 3.86 0 No Yes 5 6 2 1
R:R:M230 R:R:Y234 7.18 2 No Yes 6 7 1 1
R:R:H302 R:R:M230 5.25 2 Yes No 6 6 1 1
R:R:M237 R:R:Y234 3.59 2 Yes Yes 9 7 2 1
R:R:V305 R:R:Y234 5.05 0 No Yes 7 7 2 1
R:R:F356 R:R:Y234 10.32 2 Yes Yes 7 7 1 1
R:R:M237 R:R:Q383 8.16 2 Yes Yes 9 9 2 2
R:R:H277 R:R:L298 5.14 2 Yes No 7 6 2 1
R:R:H277 R:R:I301 10.61 2 Yes Yes 7 7 2 2
R:R:C289 R:R:L291 3.17 0 No Yes 9 6 2 1
R:R:E294 R:R:S292 4.31 0 No No 3 4 1 2
R:R:H296 R:R:L297 5.14 0 No No 2 4 1 2
R:R:H302 R:R:L298 9 2 Yes No 6 6 1 1
R:R:H302 R:R:I301 3.98 2 Yes Yes 6 7 1 2
R:R:F356 R:R:L309 3.65 2 Yes No 7 7 1 2
R:R:F356 R:R:Q355 9.37 2 Yes Yes 7 8 1 2
R:R:Q355 R:R:Q383 10.24 2 Yes Yes 8 9 2 2
R:R:F356 R:R:I380 7.54 2 Yes No 7 6 1 2
R:R:F356 R:R:Q383 5.86 2 Yes Yes 7 9 1 2
R:R:M376 R:R:Y372 3.59 0 Yes Yes 7 7 1 2
R:R:I380 R:R:M376 5.83 0 No Yes 6 7 2 1
R:R:H377 R:R:H381 8.36 0 No Yes 7 9 1 1
L:L:S35 R:R:E123 2.87 0 Yes No 0 4 0 1
L:L:F16 R:R:A145 2.77 0 No No 0 4 0 1
R:R:H201 R:R:V206 2.77 0 No No 6 3 2 1
L:L:V33 R:R:F102 2.62 0 No Yes 0 4 0 1
L:L:A14 R:R:V206 1.7 0 No No 0 3 0 1
R:R:G209 R:R:N208 1.7 0 No No 3 3 1 2
L:L:A6 R:R:M376 1.61 0 No Yes 0 7 0 1
R:R:G303 R:R:Y299 1.45 0 No No 4 7 2 1
L:L:N36 R:R:R126 1.21 0 No No 0 4 0 1
R:R:N124 R:R:R126 1.21 0 No No 5 4 1 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 9BUD_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.17
Number of Linked Nodes 385
Number of Links 435
Number of Hubs 63
Number of Links mediated by Hubs 231
Number of Communities 9
Number of Nodes involved in Communities 67
Number of Links involved in Communities 95
Path Summary
Number Of Nodes in MetaPath 81
Number Of Links MetaPath 80
Number of Shortest Paths 195368
Length Of Smallest Path 3
Average Path Length 17.7652
Length of Longest Path 36
Minimum Path Strength 1.135
Average Path Strength 6.22618
Maximum Path Strength 25.86
Minimum Path Correlation 0.7
Average Path Correlation 0.958508
Maximum Path Correlation 0.99
Minimum % Of Corr. Nodes 3.84615
Average % Of Corr. Nodes 53.8744
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 53.3031
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function
Gene OntologyBiological Process
Gene OntologyCellular Component
SCOP2Domain Identifier• Transducin (heterotrimeric G protein), gamma chain   • G protein-coupled receptor-like
SCOP2Family Identifier• Transducin (heterotrimeric G protein), gamma chain   • G protein-coupled receptor-like
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeGGL
PDB ResiduesL:L:?1
Environment DetailsOpen EMBL-EBI Page
CodeGGL
NameGlutamic acid
SynonymsGlutamic acid
Identifier
FormulaC5 H9 N O4
Molecular Weight147.129
SMILES
PubChem33032
Formal Charge0
Total Atoms19
Total Chiral Atoms1
Total Bonds18
Total Aromatic Bonds0

CodeNH2
PDB ResiduesL:L:?39
Environment DetailsOpen EMBL-EBI Page
CodeNH2
NameAMINO GROUP
Synonyms
Identifier
FormulaH2 N
Molecular Weight16.023
SMILES
PubChem123329
Formal Charge0
Total Atoms3
Total Chiral Atoms0
Total Bonds2
Total Aromatic Bonds0

Code_L_
PDB ResiduesL:L:?102
Environment DetailsOpen EMBL-EBI Page
Code_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds

PDBsumOpen PDBsum Page
ChainL
ProteinCagrilintide
UniProtP10997
Sequence
>9BUD_nogp_Chain_L


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainR
ProteinReceptor
UniProtP30988
Sequence
>9BUD_nogp_Chain_R
FLYVVGRKK MMDAQYKCY DRMQQYCNR TWDGWLCWD DTPAGVLSY 
QFCPDYFPD FDPSEKVTK YCDEKGVWF KHPENNRTW SNYTMCNAF 
TPEKLKNAY VLYYLAIVG HSLSIFTLV ISLGIFVFF RSLGCQRVT 
LHKNMFLTY ILNSMIIII HLVEVVPNG ELVRRDPVS CKILHFFHQ 
YMMACNYFW MLCEGIYLH TLIVVAVFT EKQRLRWYY LLGWGFPLV 
PTTIHAITR AVYFNDNCW LSVETHLLY IIHGPVMAA LVVNFFFLL 
NIVRVLVTK MRETHEAES HMYLKAVKA TMILVPLLG IQFVVFPWR 
PSNKMLGKI YDYVMHSLI HFQGFFVAT IYCFCNNEV QTTVKRQWA 
QFKIQW


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
3DQBASensoryOpsinsRhodopsinBos taurus--Gt(CT)3.22008-09-23doi.org/10.1038/nature07330
3PQRASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)2.852011-03-09doi.org/10.1038/nature09789
2X72ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)32011-03-16doi.org/10.1038/nature09795
4A4MASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)3.32012-01-25doi.org/10.1073/pnas.1114089108
4BEYASensoryOpsinsRhodopsinBos taurus--Gt(CT)2.92013-05-08doi.org/10.1038/embor.2013.44
4J4QASensoryOpsinsRhodopsinBos taurusOctyl β-D-Glucopyranoside-Gt(CT)2.652013-10-30doi.org/10.1002/anie.201302374
4X1HASensoryOpsinsRhodopsinBos taurusNonyl-β-D-Glucopyranoside-Gt(CT)2.292015-11-04doi.org/10.1016/j.str.2015.09.015
5EN0ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)2.812016-08-10doi.org/10.15252/embr.201642671
5UZ7B1PeptideCalcitoninCTHomo sapiens--Gs/β1/γ24.12017-05-03doi.org/10.1038/nature22327
5UZ7 (No Gprot) B1PeptideCalcitoninCTHomo sapiens--4.12017-05-03doi.org/10.1038/nature22327
5WKTASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-Gt(CT)3.22017-12-13doi.org/10.1038/nprot.2017.135
6E3YB1PeptideCalcitoninCT LikeHomo sapiensCalcitonin gene-related peptide-1-Gs/β1/γ2; RAMP13.32018-09-19doi.org/10.1038/s41586-018-0535-y
6E3Y (No Gprot) B1PeptideCalcitoninCT LikeHomo sapiensCalcitonin gene-related peptide-1-3.32018-09-19doi.org/10.1038/s41586-018-0535-y
6NIYB1PeptideCalcitoninCTHomo sapiensCalcitonin-1-Gs/β1/γ23.342019-01-23doi.org/10.1021/acsptsci.8b00056
6NIY (No Gprot) B1PeptideCalcitoninCTHomo sapiensCalcitonin-1-3.342019-01-23doi.org/10.1021/acsptsci.8b00056
6E67AAmineAdrenergicβ2Homo sapiensBI167107-Gs(CT)3.72019-06-05doi.org/10.1016/j.cell.2019.04.021
6TP4APeptideOrexinOX1Homo sapiensACT-462206--3.012020-01-01doi.org/10.1021/acs.jmedchem.9b01787
6NWEASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-Gt(CT)2.712020-02-12To be published
6UUNB1PeptideCalcitoninCT Like (AM1)Homo sapiensAdrenomedullin-Gs/β1/γ2; RAMP232020-03-25doi.org/10.1021/acsptsci.9b00080
6UUN (No Gprot) B1PeptideCalcitoninCT Like (AM1)Homo sapiensAdrenomedullin-32020-03-25doi.org/10.1021/acsptsci.9b00080
6UUSB1PeptideCalcitoninCT Like (AM2)Homo sapiensAdrenomedullin-Gs/β1/γ2; RAMP32.42020-04-01doi.org/10.1021/acsptsci.9b00080
6UUS (No Gprot) B1PeptideCalcitoninCT Like (AM2)Homo sapiensAdrenomedullin-2.42020-04-01doi.org/10.1021/acsptsci.9b00080
6UVAB1PeptideCalcitoninCT Like (AM2)Homo sapiensAdrenomedullin-2-Gs/β1/γ2; RAMP32.32020-04-01doi.org/10.1021/acsptsci.9b00080
6UVA (No Gprot) B1PeptideCalcitoninCT Like (AM2)Homo sapiensAdrenomedullin-2-2.32020-04-01doi.org/10.1021/acsptsci.9b00080
6PELASensoryOpsinsRhodopsinBos taurus-CitronellolGt(CT)3.192020-06-24To be published
6PGSASensoryOpsinsRhodopsinBos taurus-GeraniolGt(CT)2.92020-07-01To be published
6PH7ASensoryOpsinsRhodopsinBos taurus-NerolGt(CT)2.92020-07-01To be published
7KNTB1PeptideCalcitoninCT LikeHomo sapiens--RAMP13.152021-02-24doi.org/10.1126/science.abf7258
7KNUB1PeptideCalcitoninCT LikeHomo sapiensCalcitonin gene-related peptide-1-RAMP13.492021-02-24doi.org/10.1126/science.abf7258
7TYLB1PeptideCalcitoninCTHomo sapiensAmylin-Gs/β1/γ23.32022-03-23doi.org/10.1126/science.abm9609
7TYL (No Gprot) B1PeptideCalcitoninCTHomo sapiensAmylin-3.32022-03-23doi.org/10.1126/science.abm9609
7TYOB1PeptideCalcitoninCTHomo sapiensCalcitonin-Gs/β1/γ22.72022-03-23doi.org/10.1126/science.abm9609
7TYO (No Gprot) B1PeptideCalcitoninCTHomo sapiensCalcitonin-2.72022-03-23doi.org/10.1126/science.abm9609
7TYFB1PeptideCalcitoninCT (AMY1)Homo sapiensAmylin-Gs/β1/γ2; RAMP12.22022-03-23doi.org/10.1126/science.abm9609
7TYF (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensAmylin-2.22022-03-23doi.org/10.1126/science.abm9609
7TYWB1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin-1-Gs/β1/γ2; RAMP132022-03-23doi.org/10.1126/science.abm9609
7TYW (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin-1-32022-03-23doi.org/10.1126/science.abm9609
7TYHB1PeptideCalcitoninCT (AMY2)Homo sapiensCalcitonin-Gs/β1/γ2; RAMP23.32022-03-23doi.org/10.1126/science.abm9609
7TYH (No Gprot) B1PeptideCalcitoninCT (AMY2)Homo sapiensCalcitonin-3.32022-03-23doi.org/10.1126/science.abm9609
7TYYB1PeptideCalcitoninCT (AMY2)Homo sapiensCalcitonin-1-Gs/β1/γ2; RAMP232022-03-23doi.org/10.1126/science.abm9609
7TYY (No Gprot) B1PeptideCalcitoninCT (AMY2)Homo sapiensCalcitonin-1-32022-03-23doi.org/10.1126/science.abm9609
7TZFB1PeptideCalcitoninCT (AMY3)Homo sapiensAmylin-Gs/β1/γ2; RAMP32.42022-03-23doi.org/10.1126/science.abm9609
7TZF (No Gprot) B1PeptideCalcitoninCT (AMY3)Homo sapiensAmylin-2.42022-03-23doi.org/10.1126/science.abm9609
7TYIB1PeptideCalcitoninCTHomo sapiensAmylin-Gs/β1/γ23.32022-03-30doi.org/10.1126/science.abm9609
7TYI (No Gprot) B1PeptideCalcitoninCTHomo sapiensAmylin-3.32022-03-30doi.org/10.1126/science.abm9609
7TYNB1PeptideCalcitoninCTHomo sapiensCalcitonin-1-Gs/β1/γ22.62022-03-30doi.org/10.1126/science.abm9609
7TYN (No Gprot) B1PeptideCalcitoninCTHomo sapiensCalcitonin-1-2.62022-03-30doi.org/10.1126/science.abm9609
7TYXB1PeptideCalcitoninCT (AMY2)Homo sapiensAmylin-Gs/β1/γ2; RAMP22.552022-03-30doi.org/10.1126/science.abm9609
7TYX (No Gprot) B1PeptideCalcitoninCT (AMY2)Homo sapiensAmylin-2.552022-03-30doi.org/10.1126/science.abm9609
7UM5AAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-chim(NtGi1-Go)/β1/γ22.732022-07-20doi.org/10.1038/s41594-022-00796-6
7UM5 (No Gprot) AAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-2.732022-07-20doi.org/10.1038/s41594-022-00796-6
7XTCAAmine5-Hydroxytryptamine5-HT7Homo sapiens5-CT-Gs/β1/γ23.22022-07-27doi.org/10.1016/j.molcel.2022.05.031
7XTC (No Gprot) AAmine5-Hydroxytryptamine5-HT7Homo sapiens5-CT-3.22022-07-27doi.org/10.1016/j.molcel.2022.05.031
7X5HAAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-Gi1/β1/γ23.12022-09-14doi.org/10.1038/s41421-022-00412-3
7X5H (No Gprot) AAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-3.12022-09-14doi.org/10.1038/s41421-022-00412-3
8F0JB1PeptideCalcitoninCTHomo sapiensPramlintide Analogue San45-Gs/β1/γ222023-08-02doi.org/10.1038/s41589-023-01393-4
8F0J (No Gprot) B1PeptideCalcitoninCTHomo sapiensPramlintide Analogue San45-22023-08-02doi.org/10.1038/s41589-023-01393-4
8F0KB1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide Analogue San385-Gs/β1/γ2; RAMP31.92023-08-02doi.org/10.1038/s41589-023-01393-4
8F0K (No Gprot) B1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide Analogue San385-1.92023-08-02doi.org/10.1038/s41589-023-01393-4
8F2AB1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide Analogue San385-Gs/β1/γ2; RAMP32.22023-08-02doi.org/10.1038/s41589-023-01393-4
8F2A (No Gprot) B1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide Analogue San385-2.22023-08-02doi.org/10.1038/s41589-023-01393-4
8F2BB1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide Analogue San45-Gs/β1/γ2; RAMP322023-08-02doi.org/10.1038/s41589-023-01393-4
8F2B (No Gprot) B1PeptideCalcitoninCT (AMY3)Homo sapiensPramlintide Analogue San45-22023-08-02doi.org/10.1038/s41589-023-01393-4
8ZQEAOrphanOrphanGPR15Homo sapiensGPR15L(CT)-Gi1/β1/γ12.92024-07-10doi.org/10.1038/s41421-024-00698-5
8ZQE (No Gprot) AOrphanOrphanGPR15Homo sapiensGPR15L(CT)-2.92024-07-10doi.org/10.1038/s41421-024-00698-5
9MNIB1PeptideCalcitoninCTLikeHomo sapiensdC2_05-RAMP14.062025-10-22doi.org/10.1101/2025.03.23.644666
9AUCB1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin gene-related peptide-1-Gs/β1/γ2; RAMP12.42024-04-24doi.org/10.1021/acs.biochem.4c00114
9AUC (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCalcitonin gene-related peptide-1-2.42024-04-24doi.org/10.1021/acs.biochem.4c00114
9BLBB1PeptideCalcitoninCTHomo sapiensCagrilintide (non-acylated)-Gs/β1/γ23.22025-04-16doi.org/10.1038/s41467-025-58680-y
9BLB (No Gprot) B1PeptideCalcitoninCTHomo sapiensCagrilintide (non-acylated)-3.22025-04-16doi.org/10.1038/s41467-025-58680-y
9BLCB1PeptideCalcitoninCTHomo sapiensCagrilintide (non-acylated)-Gs/β1/γ23.32025-04-16doi.org/10.1038/s41467-025-58680-y
9BLC (No Gprot) B1PeptideCalcitoninCTHomo sapiensCagrilintide (non-acylated)-3.32025-04-16doi.org/10.1038/s41467-025-58680-y
9BUEB1PeptideCalcitoninCTHomo sapiensCagrilintide-Gs/β1/γ23.62025-04-16doi.org/10.1038/s41467-025-58680-y
9BUE (No Gprot) B1PeptideCalcitoninCTHomo sapiensCagrilintide-3.62025-04-16doi.org/10.1038/s41467-025-58680-y
9BLWB1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide (non-acylated)-Gs/β1/γ2; RAMP13.22025-04-16doi.org/10.1038/s41467-025-58680-y
9BLW (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide (non-acylated)-3.22025-04-16doi.org/10.1038/s41467-025-58680-y
9BTWB1PeptideCalcitoninCT (AMY3)Homo sapiensCagrilintide-Gs/β1/γ2; RAMP332025-04-16To be published
9BTW (No Gprot) B1PeptideCalcitoninCT (AMY3)Homo sapiensCagrilintide-32025-04-16To be published
9BUBB1PeptideCalcitoninCTHomo sapiensCagrilintide-Gs/β1/γ22.32025-04-23doi.org/10.1038/s41467-025-58680-y
9BUB (No Gprot) B1PeptideCalcitoninCTHomo sapiensCagrilintide-2.32025-04-23doi.org/10.1038/s41467-025-58680-y
9BUCB1PeptideCalcitoninCTHomo sapiensCagrilintide-Gs/β1/γ23.42025-04-23doi.org/10.1038/s41467-025-58680-y
9BUC (No Gprot) B1PeptideCalcitoninCTHomo sapiensCagrilintide-3.42025-04-23doi.org/10.1038/s41467-025-58680-y
9BUDB1PeptideCalcitoninCTHomo sapiensCagrilintide-Gs/β1/γ22.52025-04-23doi.org/10.1038/s41467-025-58680-y
9BUD (No Gprot) B1PeptideCalcitoninCTHomo sapiensCagrilintide-2.52025-04-23doi.org/10.1038/s41467-025-58680-y
9BP3B1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide-Gs/β1/γ2; RAMP12.22025-04-23doi.org/10.1038/s41467-025-58680-y
9BP3 (No Gprot) B1PeptideCalcitoninCT (AMY1)Homo sapiensCagrilintide-2.22025-04-23doi.org/10.1038/s41467-025-58680-y
9BQ3B1PeptideCalcitoninCT (AMY2)Homo sapiensCagrilintide-Gs/β1/γ2; RAMP22.82025-04-23doi.org/10.1038/s41467-025-58680-y
9BQ3 (No Gprot) B1PeptideCalcitoninCT (AMY2)Homo sapiensCagrilintide-2.82025-04-23doi.org/10.1038/s41467-025-58680-y
9UAPAAmineAcetylcholine (muscarinic)M1Homo sapiens--G11(CT)3.622025-10-29To be published
9UCPAAmineAcetylcholine (muscarinic)M1Homo sapiensIperoxo-G11(CT)2.882025-10-29To be published
9WXMAOrphanOrphanGPR15Homo sapiensGPR15L(CT)-Gi3/β1/γ23.32025-11-1910.1016/j.isci.2025.113935
9WXM (No Gprot) AOrphanOrphanGPR15Homo sapiensGPR15L(CT)-3.32025-11-1910.1016/j.isci.2025.113935
9W6WAAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-Gi1/β1/γ23.132025-11-2610.1186/s43556-025-00359-3
9W6W (No Gprot) AAmine5-Hydroxytryptamine5-HT5AHomo sapiens5-CT-3.132025-11-2610.1186/s43556-025-00359-3




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