Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index Hub Avg Int. Strength Num Of Links Community ConSurf
1R:R:N2 6.1525406
2R:R:E5 8.352516
3R:R:Y10 7.045817
4R:R:V11 4.0425418
5R:R:P12 4.978518
6R:R:F13 4.95404
7R:R:V20 6.64406
8R:R:S22 5.27415
9R:R:P23 5.684515
10R:R:F24 7.435615
11R:R:Y30 7.694514
12R:R:L31 7.475414
13R:R:Q36 8.434102
14R:R:F37 6.6575405
15R:R:N55 7.03409
16R:R:P71 4.8425406
17R:R:N78 6.6154159
18R:R:D83 6.3675409
19R:R:F91 7.2375447
20R:R:S98 3.1625405
21R:R:F103 6.29167618
22R:R:C110 5.2075419
23R:R:E122 8.3775426
24R:R:I123 5.4985157
25R:R:W126 6.85833625
26R:R:R135 8.475449
27R:R:Y136 6.021676167
28R:R:V139 3.5925408
29R:R:E150 7.1925402
30R:R:P170 4.385427
31R:R:W175 9.5675425
32R:R:R177 5.47515
33R:R:Y178 5.595623
34R:R:P180 6.15513
35R:R:E181 6.97424
36R:R:M183 5.8625102
37R:R:Q184 5.676513
38R:R:I189 5.1775424
39R:R:D190 6.75333614
40R:R:Y191 8.085406
41R:R:Y192 8.844515
42R:R:T193 7.694515
43R:R:H195 9.6325414
44R:R:N200 5.895414
45R:R:F203 6.97571726
46R:R:Y206 6.28424
47R:R:H211 9.286526
48R:R:F212 5.66667628
49R:R:Y223 5.97509
50R:R:Q237 6.0825465
51R:R:T243 3.7775465
52R:R:M257 7.3525448
53R:R:F261 8.2525429
54R:R:W265 10.076508
55R:R:Y268 8.315626
56R:R:Y301 4.38833645
57R:R:N302 6.138549
58R:R:Y306 6.965649
59R:R:K311 6.54254174
60R:R:Q312 4.4575406
61L:L:?1 8.05571720
62K:K:F15 7.226508
63K:K:R19 9.15754189
64K:K:W186 8.424506
65K:K:R191 5.616509
66K:K:E200 5.54409
67K:K:Q205 6.272509
68K:K:M206 5.44408
69K:K:K207 9.3408
70K:K:Y213 4.845409
71K:K:K216 5.975499
72K:K:K221 10.7825478
73K:K:R222 7.936579
74K:K:K224 7.03833659
75K:K:Y229 7.454558
76K:K:E235 5.764599
77K:K:I238 5.3325407
78K:K:F246 6.9154199
79K:K:Y252 6.8409
80K:K:E255 4.3525457
81K:K:L262 3.835408
82K:K:I272 6.36488
83K:K:R273 6.6954207
84K:K:H275 8.815409
85K:K:N283 5.07404
86K:K:F286 7.43667687
87K:K:Q287 3.2775403
88K:K:R290 8.62167689
89K:K:Y294 5.87714789
90K:K:E303 5.34754224
91K:K:I311 4.97436
92K:K:Y312 3.7875409
93K:K:R313 7.384539
94K:K:K316 13.3054239
95K:K:L322 8.315489
96K:K:V328 5.3725488
97K:K:L333 4.9675409
98K:K:L339 6.36405
99K:K:T352 6.64254239
100K:K:M356 6.69439
101K:K:P358 4.7375409
102K:K:E359 7.622539
103K:K:L360 6.4625438
104K:K:L361 5.1725438
105K:K:Y366 5.49739
106K:K:Y372 7.31408
107K:K:F373 6.5775438
108K:K:Y380 4.57857736
109K:K:I383 4.8575407
110K:K:P388 6.056539
111K:K:F389 5.86439
112K:K:V410 4.91537
113K:K:Y412 6.505637
114K:K:F416 5.986539
115K:K:F423 9.3085115
116K:K:D431 7.3675405
117K:K:P432 7.085435
118K:K:R435 7.004539
119K:K:L446 4.3445116
120K:K:F452 5.89754118
121K:K:I455 4.17333606
122K:K:P467 4.464506
123K:K:D472 5.5475468
124K:K:R474 10.3275465
125K:K:Y477 6.0325469
126K:K:Q482 5.7885174
127K:K:F487 11.685478
128K:K:E489 12.4275477
129K:K:D499 8.192559
130K:K:F502 6.6725458
131K:K:F503 9.27457
132K:K:F506 8.2459
   

Color ConSurf Grade
      No Conservation data available
      1
      2
      3
      4
      5
      6
      7
      8
      9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index Node1 Node2 Recurrence Int. Strength Hub1? Hub2? Community ConSurf1 ConSurf2
1R:R:Y10 R:R:Y192 10.12085.96YesYes175
2R:R:P12 R:R:Y192 41.15754.17YesYes185
3R:R:P12 R:R:V11 10.09683.53YesYes188
4R:R:P12 R:R:Q184 22.55046.32YesYes183
5R:R:P180 R:R:Q184 15.36466.32YesYes133
6R:R:Y191 R:R:Y192 58.707419.86YesYes065
7R:R:Y191 R:R:Y268 60.5885.96YesYes066
8L:L:?1 R:R:Y268 62.379622.61YesYes206
9L:L:?1 R:R:W265 66.16836.06YesYes008
10R:R:C264 R:R:W265 57.336918.28NoYes088
11R:R:C264 R:R:Y301 28.90124.03NoYes485
12R:R:L79 R:R:N302 17.97174.12NoYes099
13R:R:N302 R:R:S298 28.86017.45YesNo499
14R:R:C264 R:R:S298 28.73186.89NoNo489
15R:R:N302 R:R:Y301 36.42274.65YesYes495
16L:L:?1 R:R:F212 20.23814.05YesYes208
17R:R:F212 R:R:F261 21.68914.29YesYes289
18R:R:F261 R:R:I219 44.453118.84YesNo098
19R:R:I219 R:R:Y223 44.51693.63NoYes089
20R:R:M257 R:R:Y223 46.309810.78YesYes089
21R:R:M257 R:R:R135 45.46624.96YesYes489
22K:K:E7 R:R:R135 98.04946.98NoYes089
23K:K:E7 R:R:N310 98.002917.09NoNo088
24K:K:T8 R:R:N310 97.56964.39NoNo088
25K:K:T8 R:R:K311 92.15826.01NoYes084
26K:K:Q482 R:R:K311 91.7455.42YesYes1744
27K:K:Q482 R:R:Q312 16.48353.84YesYes046
28R:R:F261 R:R:W265 23.93815.01YesYes098
29R:R:N302 R:R:Y306 53.40973.49YesYes499
30R:R:R135 R:R:Y306 52.52326.17YesYes499
31R:R:K67 R:R:Q312 11.75025.42NoYes056
32K:K:E200 R:R:K67 11.81275.4YesNo095
33R:R:L79 R:R:S127 16.03077.51NoNo098
34R:R:I75 R:R:S127 15.95556.19NoNo078
35R:R:E134 R:R:I75 14.3056.83NoNo1487
36R:R:E134 R:R:F148 16.429110.49NoNo087
37R:R:F148 R:R:P71 16.52448.67NoYes076
38R:R:P71 R:R:T70 13.5733.5YesNo067
39K:K:E200 R:R:T70 13.58664.23YesNo097
40K:K:K221 R:R:E150 14.59965.4YesYes082
41R:R:E150 R:R:P71 16.19393.14YesYes026
42R:R:L125 R:R:W265 12.832718.22NoYes078
43K:K:F15 K:K:R191 15.73729.62YesYes089
44K:K:N480 K:K:R191 99.89287.23NoYes089
45K:K:N480 K:K:Q482 1003.96NoYes084
46K:K:I16 K:K:N12 88.8365.66NoNo089
47K:K:N12 K:K:R191 88.98984.82NoYes099
48K:K:I16 R:R:Q237 85.5375.49NoYes685
49K:K:T475 R:R:Q237 85.1984.25NoYes665
50K:K:C261 K:K:F254 10.30512.57NoNo087
51K:K:C215 K:K:C261 10.24643.64NoNo098
52K:K:C215 K:K:F202 10.35374.19NoNo096
53K:K:E235 K:K:L239 11.05623.98YesNo099
54K:K:L239 K:K:L333 11.66575.54NoYes099
55K:K:L305 K:K:L333 26.84974.15NoYes099
56K:K:L305 K:K:Y312 29.79323.52NoYes099
57K:K:L315 K:K:Y312 14.09684.69NoYes079
58K:K:L315 K:K:T378 14.43367.37NoNo078
59K:K:P317 K:K:T378 14.61496.99NoNo098
60K:K:P317 K:K:R273 14.79995.76NoYes2097
61K:K:D271 K:K:R273 91.63853.57NoYes097
62K:K:D271 K:K:Y274 91.81113.45NoNo096
63K:K:Y274 K:K:Y477 91.8923.97NoYes669
64K:K:T475 K:K:Y477 84.81576.24NoYes669
65K:K:N319 K:K:Y312 14.09453.49NoYes099
66K:K:K316 K:K:N319 14.3313.99YesNo099
67K:K:E318 K:K:K316 76.352517.55NoYes099
68K:K:E318 K:K:R273 76.54175.82NoYes097
69K:K:I247 K:K:V242 13.59884.61NoNo097
70K:K:L333 K:K:V242 14.18174.47YesNo097
71K:K:H304 K:K:S244 11.87568.37NoNo089
72K:K:I247 K:K:S244 12.4444.64NoNo099
73K:K:L379 K:K:M382 13.73854.24NoNo069
74K:K:I383 K:K:L379 14.61494.28YesNo076
75K:K:F416 K:K:I383 21.90467.54YesYes097
76K:K:F416 K:K:Y380 21.26574.13YesYes396
77K:K:P388 K:K:Y380 20.71176.95YesYes396
78K:K:P388 K:K:V377 24.31057.07YesNo099
79K:K:F355 K:K:V377 24.52055.24NoNo099
80K:K:F355 K:K:K316 24.156511.17NoYes2399
81K:K:F452 K:K:I455 13.5973.77YesYes086
82K:K:F452 K:K:L446 15.05573.65YesYes1186
83K:K:L446 K:K:Y372 24.05653.52YesYes068
84K:K:H306 K:K:Y372 28.536910.89NoYes098
85K:K:D371 K:K:H306 32.235812.61NoNo099
86K:K:D371 K:K:I311 32.97417NoYes096
87K:K:I311 K:K:R313 14.0883.76YesYes369
88K:K:L360 K:K:R313 16.19554.86YesYes389
89K:K:L360 K:K:M356 34.66885.65YesYes389
90K:K:G351 K:K:M356 37.39563.49NoYes099
91K:K:D314 K:K:G351 37.82396.71NoNo099
92K:K:D314 K:K:T352 36.17738.67NoYes099
93K:K:K316 K:K:T352 38.340710.51YesYes2399
94K:K:I311 K:K:Y366 22.54164.84YesYes369
95K:K:L360 K:K:Y366 17.40759.38YesYes389
96K:K:F373 K:K:F389 12.21114.29YesYes389
97K:K:E359 K:K:Y366 11.02944.49YesYes399
98L:L:?1 R:R:M207 19.11746.58YesNo205
Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.


2D representation of the interactions of this orthosteric/allosteric ligand.


Links and nodes colored according to ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

Node1 Node2 LinkStrength Comm IsNode1Hub? IsNode2Hub? Node1Cons Node2Cons Node1Shell Node2Shell
R:R:K296 R:R:M44 4.32 0 No No 7 7 1 2
R:R:F91 R:R:K296 12.41 4 Yes No 7 7 2 1
L:L:?1 R:R:A117 4.19 2 Yes No 0 5 0 1
R:R:L125 R:R:W265 18.22 2 No Yes 7 8 2 1
R:R:E181 R:R:S186 7.19 2 Yes No 4 5 1 2
R:R:E181 R:R:G188 8.19 2 Yes No 4 5 1 2
R:R:E181 R:R:Y268 8.98 2 Yes Yes 4 6 1 1
L:L:?1 R:R:E181 3.52 2 Yes Yes 0 4 0 1
R:R:F203 R:R:I189 3.77 2 Yes Yes 6 4 2 2
R:R:I189 R:R:M207 8.75 2 Yes No 4 5 2 1
R:R:Y191 R:R:Y268 5.96 0 Yes Yes 6 6 2 1
R:R:F203 R:R:M207 11.2 2 Yes No 6 5 2 1
L:L:?1 R:R:M207 6.58 2 Yes No 0 5 0 1
R:R:F212 R:R:I213 3.77 2 Yes No 8 4 1 2
R:R:F212 R:R:L216 6.09 2 Yes No 8 7 1 2
R:R:F212 R:R:F261 4.29 2 Yes Yes 8 9 1 2
R:R:F212 R:R:L266 6.09 2 Yes No 8 6 1 2
R:R:A269 R:R:F212 9.71 0 No Yes 7 8 2 1
L:L:?1 R:R:F212 4.05 2 Yes Yes 0 8 0 1
R:R:F261 R:R:L216 4.87 2 Yes No 9 7 2 2
R:R:F261 R:R:W265 5.01 2 Yes Yes 9 8 2 1
R:R:C264 R:R:W265 18.28 4 No Yes 8 8 2 1
L:L:?1 R:R:W265 6.06 2 Yes Yes 0 8 0 1
R:R:P291 R:R:Y268 8.34 0 No Yes 6 6 2 1
L:L:?1 R:R:Y268 22.61 2 Yes Yes 0 6 0 1
L:L:?1 R:R:K296 9.38 2 Yes No 0 7 0 1
R:R:G121 R:R:W265 2.81 0 No Yes 7 8 2 1
R:R:A295 R:R:Y268 2.67 0 No Yes 8 6 2 1
R:R:A292 R:R:Y268 1.33 0 No Yes 5 6 2 1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB 7MT8_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.
Net Summary
Imin 3.45
Number of Linked Nodes 651
Number of Links 795
Number of Hubs 132
Number of Links mediated by Hubs 476
Number of Communities 23
Number of Nodes involved in Communities 186
Number of Links involved in Communities 262
Path Summary
Number Of Nodes in MetaPath 99
Number Of Links MetaPath 98
Number of Shortest Paths 691594
Length Of Smallest Path 3
Average Path Length 26.8672
Length of Longest Path 52
Minimum Path Strength 1.49
Average Path Strength 7.05198
Maximum Path Strength 21.735
Minimum Path Correlation 0.7
Average Path Correlation 0.966985
Maximum Path Correlation 1
Minimum % Of Corr. Nodes 3.0303
Average % Of Corr. Nodes 48.0466
Maximum % Of Corr. Nodes 100
Minimum Path Hubs % 0
Average Path Hubs % 51.7507
Maximum Path Hubs % 100
AnnotationTypeLinks
Gene OntologyMolecular Function• binding   • adenyl ribonucleotide binding   • nucleotide binding   • purine ribonucleotide binding   • purine ribonucleoside triphosphate binding   • nucleoside phosphate binding   • ion binding   • purine nucleotide binding   • anion binding   • adenyl nucleotide binding   • ATP binding   • heterocyclic compound binding   • carbohydrate derivative binding   • ribonucleotide binding   • small molecule binding   • protein serine/threonine kinase activity   • catalytic activity, acting on a protein   • kinase activity   • protein kinase activity   • transferase activity   • G protein-coupled receptor kinase activity   • catalytic activity   • rhodopsin kinase activity   • phosphotransferase activity, alcohol group as acceptor   • transferase activity, transferring phosphorus-containing groups   • cellular response to stimulus   • regulation of biological process   • regulation of signaling   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • regulation of signal transduction   • cell communication   • regulation of response to stimulus   • regulation of cell communication   • cellular process   • signal transduction   • multicellular organismal process
Gene OntologyBiological Process• cellular response to stimulus   • regulation of biological process   • regulation of signaling   • regulation of cellular process   • response to stimulus   • signaling   • biological regulation   • regulation of signal transduction   • cell communication   • regulation of response to stimulus   • regulation of cell communication   • cellular process   • signal transduction   • multicellular organismal process   • sensory perception of light stimulus   • system process   • sensory perception   • nervous system process   • visual perception   • response to light stimulus   • regulation of response to external stimulus   • regulation of opsin-mediated signaling pathway   • detection of abiotic stimulus   • cellular response to environmental stimulus   • cellular response to light stimulus   • regulation of G protein-coupled receptor signaling pathway   • detection of light stimulus   • phototransduction   • detection of external stimulus   • detection of visible light   • response to external stimulus   • cellular response to radiation   • detection of stimulus   • response to radiation   • response to abiotic stimulus   • G protein-coupled receptor signaling pathway   • cellular response to abiotic stimulus   • G protein-coupled opsin signaling pathway   • phototransduction, visible light   • protein phosphorylation   • protein autophosphorylation   • phosphorylation   • primary metabolic process   • macromolecule modification   • phosphate-containing compound metabolic process   • metabolic process   • protein metabolic process   • macromolecule metabolic process   • protein modification process   • phosphorus metabolic process   • membrane-bounded organelle   • non-motile cilium   • membrane   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • cellular anatomical structure   • photoreceptor cell cilium   • organelle   • organelle membrane
Gene OntologyCellular Component• membrane-bounded organelle   • non-motile cilium   • membrane   • 9+0 non-motile cilium   • cilium   • neuron projection   • photoreceptor disc membrane   • photoreceptor outer segment   • plasma membrane bounded cell projection   • cell projection   • cellular anatomical structure   • photoreceptor cell cilium   • organelle   • organelle membrane   • intracellular anatomical structure   • cytoplasm   • opsin binding   • protein binding   • binding   • arrestin family protein binding   • G protein-coupled photoreceptor activity   • molecular transducer activity   • photoreceptor activity   • G protein-coupled receptor activity   • transmembrane signaling receptor activity   • signaling receptor activity   • vitamin binding   • retinal binding   • isoprenoid binding   • retinoid binding   • lipid binding   • 11-cis retinal binding   • small molecule binding   • G-protein alpha-subunit binding   • enzyme regulator activity   • guanyl nucleotide binding   • GTP binding   • nucleotide binding   • hydrolase activity   • guanyl ribonucleotide binding   • GDP binding   • purine ribonucleotide binding   • ion binding   • ribonucleoside triphosphate phosphatase activity   • anion binding   • molecular function regulator activity   • heterocyclic compound binding   • carbohydrate derivative binding   • hydrolase activity, acting on acid anhydrides   • catalytic activity   • ribonucleotide binding   • pyrophosphatase activity   • GTPase activity   • nucleoside-triphosphatase regulator activity   • GTPase regulator activity   • purine ribonucleoside triphosphate binding   • guanyl-nucleotide exchange factor activity   • nucleoside phosphate binding   • purine nucleotide binding   • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides   • cation binding   • transition metal ion binding   • zinc ion binding   • metal ion binding   • identical protein binding   • multicellular organismal process   • rod bipolar cell differentiation   • cellular developmental process   • sensory organ development   • retina development in camera-type eye   • visual system development   • neural retina development   • neurogenesis   • multicellular organism development   • eye morphogenesis   • neuron differentiation   • cell differentiation   • anatomical structure development   • animal organ morphogenesis   • sensory system development   • system development   • developmental process   • camera-type eye morphogenesis   • eye development   • animal organ development   • nervous system development   • retinal bipolar neuron differentiation   • glutamatergic neuron differentiation   • generation of neurons   • retina morphogenesis in camera-type eye   • anatomical structure morphogenesis   • sensory organ morphogenesis   • camera-type eye development   • cellular process   • cellular response to stimulus   • response to light stimulus   • response to stimulus   • cellular response to light stimulus   • response to radiation   • response to abiotic stimulus   • cellular response to radiation   • cellular response to abiotic stimulus   • cellular response to environmental stimulus   • regulation of cellular process   • signaling   • detection of abiotic stimulus   • cell communication   • signal transduction   • detection of light stimulus   • phototransduction   • detection of external stimulus   • regulation of biological process   • biological regulation   • detection of visible light   • response to external stimulus   • detection of stimulus   • G protein-coupled receptor signaling pathway   • G protein-coupled opsin signaling pathway   • phototransduction, visible light   • response to light intensity   • podosome assembly   • organelle assembly   • protein-containing complex organization   • membraneless organelle assembly   • cellular component organization   • cellular component biogenesis   • organelle organization   • cellular component assembly   • protein-containing complex assembly   • cellular component organization or biogenesis   • biosynthetic process   • metabolic process   • macromolecule metabolic process   • gene expression   • macromolecule biosynthetic process   • multicellular organismal-level homeostasis   • homeostatic process   • anatomical structure homeostasis   • tissue homeostasis   • retina homeostasis   • photoreceptor cell maintenance   • absorption of visible light   • light absorption   • microtubule cytoskeleton organization   • microtubule-based process   • cytoskeleton organization   • sensory perception of light stimulus   • system process   • sensory perception   • nervous system process   • visual perception   • thermoception   • sensory perception of temperature stimulus   • detection of temperature stimulus involved in sensory perception   • response to temperature stimulus   • detection of temperature stimulus involved in thermoception   • detection of temperature stimulus   • detection of stimulus involved in sensory perception   • taxis   • thermotaxis   • locomotion   • cell-cell junction   • anchoring junction   • cell junction   • cell periphery   • protein-containing complex   • plasma membrane protein complex   • plasma membrane   • plasma membrane signaling receptor complex   • G protein-coupled receptor complex   • membrane protein complex   • receptor complex   • sperm midpiece   • 9+2 motile cilium   • sperm flagellum   • motile cilium   • photoreceptor inner segment membrane   • plasma membrane region   • photoreceptor inner segment   • ciliary membrane   • photoreceptor outer segment membrane   • bounding membrane of organelle   • cell projection membrane   • Golgi membrane   • Golgi apparatus   • intracellular membrane-bounded organelle   • endomembrane system   • intracellular organelle   • outer membrane   • sperm head   • sperm head plasma membrane   • sperm plasma membrane   • rod photoreceptor outer segment
SCOP2Domain Identifier• G protein-coupled receptor-like
SCOP2Family Identifier• G protein-coupled receptor-like
Membrane Protein Annotations-• Orientations of Proteins in Membranes database (OPM)   • Protein Data Bank of Transmembrane Proteins (PDBTM)   • MemProtMD


Details about the values in these tables can be found in the corresponding documentation page .
CodeRET
PDB ResiduesL:L:?1
Environment DetailsOpen EMBL-EBI Page
CodeRET
NameRETINAL
Synonyms
Identifier
FormulaC20 H28 O
Molecular Weight284.436
SMILES
PubChem638015
Formal Charge0
Total Atoms49
Total Chiral Atoms0
Total Bonds49
Total Aromatic Bonds0

PDBsumOpen PDBsum Page
ChainR
ProteinReceptor
UniProtP02699
Sequence
>7MT8_nogp_Chain_R
MNGTEGPNF YVPFSNKTG VVRSPFEAP QYYLAEPWQ FSMLAAYMF 
LLIMLGFPI NFLTLYVTV QHKKLRTPL NYILLNLAV ADLFMVFGG 
FTTTLYTSL HGYFVFGPT GCNLEGFFA TLGGEIALW SLVVLAIER 
YVVVCKPMS NFRFGENHA IMGVAFTWV MALACAAPP LVGWSRYIP 
EGMQCSCGI DYYTPHEET NNESFVIYM FVVHFIIPL IVIFFCYGQ 
LVFTVKEAA AQQQESATT QKAEKEVTR MVIIMVIAF LICWLPYAG 
VAFYIFTHQ GSDFGPIFM TIPAFFAKT SAVYNPVIY IMMNKQFRN 
CMVTTLCCG


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  

ChainK
ProteinKinase
UniProtP28327
Sequence
>7MT8_nogp_Chain_K
LETVVANSA FIAARGSFD AMGEDWFLD FRVLGRGGF GEVFACQMK 
ATGKLYACK KLNKKRLKK RKGYQGAMV EKKILAKVH SRFIVSLAY 
AFETKTDLC LVMTIMNGG DIRYHIYNV DEDNPGFQE PRAIFYTAQ 
IVSGLEHLH QRNIIYRDL KPENVLLDD DGNVRISDL GLAVELKAG 
QTKTKGYAG TPGFMAPEL LLGEEYDFS VDYFALGVT LYEMIAARG 
PFRARGEKV ENKELKQRV LEQAVTYPD KFSPASKDF CEALLQKDP 
EKRLGFRDG SCDGLRTHP LFRDISWRQ LEAGMLTPP FVPDSRTVY 
AKNIQDVGA FEEVKGVAF EKADTEFFQ EFAS


Click on each residue to open a popup with some information about it.

ConSurf Conservation Grade (See documentation): 

 n/a   1    2    3    4    5    6    7    8    9  




This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show PDB Class SubFamily Type SubType Species Orthosteric Ligand Other Ligand(s) Protein Partners Resolution Date DOI
8P15ASensoryOpsinRhodopsinBos taurus--Gi1/β1/γT15.92024-11-20To be published
8P15 (No Gprot) ASensoryOpsinRhodopsinBos taurus--5.92024-11-20To be published
8P13ASensoryOpsinRhodopsinBos taurus--Gi1/β1/γT15.22024-11-20To be published
8P13 (No Gprot) ASensoryOpsinRhodopsinBos taurus--5.22024-11-20To be published
8P12ASensoryOpsinsRhodopsinBos taurus--Gi1/β1/γT13.212024-11-20To be published
8P12 (No Gprot) ASensoryOpsinsRhodopsinBos taurus--3.212024-11-20To be published
9EPRASensoryOpsinsRhodopsinHasarius adansoniRetinal-Gi1/β1/γ24.92024-10-30doi.org/10.1038/s41467-024-53208-2
9EPR (No Gprot) ASensoryOpsinsRhodopsinHasarius adansoniRetinal-4.92024-10-30doi.org/10.1038/s41467-024-53208-2
9EPQASensoryOpsinsRhodopsinHasarius adansoni11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ24.152024-10-2310.1038/s41467-024-53208-2
9EPQ (No Gprot) ASensoryOpsinsRhodopsinHasarius adansoni11,20-Ethanoretinal-4.152024-10-2310.1038/s41467-024-53208-2
9EPPASensoryOpsinsRhodopsinHasarius adansoni11,20-Ethanoretinal-chim(Gi1-CtGq)/β1/γ24.062024-10-2310.1038/s41467-024-53208-2
9EPP (No Gprot) ASensoryOpsinsRhodopsinHasarius adansoni11,20-Ethanoretinal-4.062024-10-2310.1038/s41467-024-53208-2
8FD1ASensoryOpsinsRhodopsinBos taurus---4.252023-08-3010.1038/s41467-023-40911-9
8FD1 (Multimeric) ASensoryOpsinsRhodopsinBos taurus--4.252023-08-3010.1038/s41467-023-40911-9
8FD0ASensoryOpsinsRhodopsinBos taurus---3.712023-08-3010.1038/s41467-023-40911-9
8FD0 (Multimeric) ASensoryOpsinsRhodopsinBos taurus--3.712023-08-3010.1038/s41467-023-40911-9
8FCZASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--3.72023-08-3010.1038/s41467-023-40911-9
8FCZ (Multimeric) ASensoryOpsinsRhodopsinBos taurus11-cis-Retinal-3.72023-08-3010.1038/s41467-023-40911-9
8A6EASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal--1.82023-03-2910.1038/s41586-023-05863-6
8A6DASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal--1.82023-03-2910.1038/s41586-023-05863-6
8A6CASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal--1.82023-03-2910.1038/s41586-023-05863-6
7ZBEASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--1.82023-03-2910.1038/s41586-023-05863-6
7ZBCASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--1.82023-03-2910.1038/s41586-023-05863-6
7MTBASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK142021-07-0710.1038/s41586-021-03721-x
7MTB (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-42021-07-0710.1038/s41586-021-03721-x
7MTAASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK14.12021-07-0710.1038/s41586-021-03721-x
7MTA (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-4.12021-07-0710.1038/s41586-021-03721-x
7MT9ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK172021-07-0710.1038/s41586-021-03721-x
7MT9 (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-72021-07-0710.1038/s41586-021-03721-x
7MT8ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-GRK15.82021-07-0710.1038/s41586-021-03721-x
7MT8 (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-5.82021-07-0710.1038/s41586-021-03721-x
6PH7ASensoryOpsinsRhodopsinBos taurus-NerolGt(CT)2.92020-07-01To be published
6PH7 (No Gprot) ASensoryOpsinsRhodopsinBos taurus-Nerol2.92020-07-01To be published
6PGSASensoryOpsinsRhodopsinBos taurus-GeraniolGt(CT)2.92020-07-01To be published
6PGS (No Gprot) ASensoryOpsinsRhodopsinBos taurus-Geraniol2.92020-07-01To be published
6PELASensoryOpsinsRhodopsinBos taurus-CitronellolGt(CT)3.192020-06-24To be published
6PEL (No Gprot) ASensoryOpsinsRhodopsinBos taurus-Citronellol3.192020-06-24To be published
6NWEASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-Gt(CT)2.712020-02-12To be published
6NWE (No Gprot) ASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-2.712020-02-12To be published
6OFJASensoryOpsinsRhodopsinBos taurus---4.52019-08-2110.1074/jbc.RA119.010089
6OFJ (Multimeric) ASensoryOpsinsRhodopsinBos taurus--4.52019-08-2110.1074/jbc.RA119.010089
6OYAASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt/β1/γ13.32019-07-2410.1016/j.molcel.2019.06.007
6OYA (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-3.32019-07-2410.1016/j.molcel.2019.06.007
6OY9ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt/β1/γ13.92019-07-2410.1016/j.molcel.2019.06.007
6OY9 (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-3.92019-07-2410.1016/j.molcel.2019.06.007
6QNOASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gi1/β1/γ14.382019-07-1010.7554/eLife.46041
6QNO (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-4.382019-07-1010.7554/eLife.46041
6I9KASensoryOpsinsRhodopsinHasarius adansoni9-cis-Retinal--2.152019-07-0310.1073/pnas.1902192116
6FUFASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Go3.122018-10-0310.1126/sciadv.aat7052
6FUF (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-3.122018-10-0310.1126/sciadv.aat7052
6CMOASensoryOpsinsRhodopsinHomo sapiens--Gi1/β1/γ24.52018-06-2010.1038/s41586-018-0215-y
6CMO (No Gprot) ASensoryOpsinsRhodopsinHomo sapiens--4.52018-06-2010.1038/s41586-018-0215-y
6FKDASensoryOpsinsRhodopsinBos taurus-PubChem 137349183-2.492018-04-0410.1073/pnas.1718084115
6FKCASensoryOpsinsRhodopsinBos taurus-PubChem 132473039-2.462018-04-0410.1073/pnas.1718084115
6FKBASensoryOpsinsRhodopsinBos taurus-PubChem 132473038-3.032018-04-0410.1073/pnas.1718084115
6FKAASensoryOpsinsRhodopsinBos taurus-PubChem 132473037-2.72018-04-0410.1073/pnas.1718084115
6FK9ASensoryOpsinsRhodopsinBos taurus-PubChem 132473036-2.632018-04-0410.1073/pnas.1718084115
6FK8ASensoryOpsinsRhodopsinBos taurus-PubChem 132473035-2.872018-04-0410.1073/pnas.1718084115
6FK7ASensoryOpsinsRhodopsinBos taurus-PubChem 132473034-2.622018-04-0410.1073/pnas.1718084115
6FK6ASensoryOpsinsRhodopsinBos taurus-PubChem 132473033-2.362018-04-0410.1073/pnas.1718084115
5WKTASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-Gt(CT)3.22017-12-1310.1038/nprot.2017.135
5WKT (No Gprot) ASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-3.22017-12-1310.1038/nprot.2017.135
5W0PASensoryOpsinsRhodopsinHomo sapiens--Arrestin13.012017-08-0910.1016/j.cell.2017.07.002
5TE5ASensoryOpsinsRhodopsinBos taurus20-Methanoretinal--4.012017-03-1510.1073/pnas.1617446114
5TE3ASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside--2.72017-03-1510.1073/pnas.1617446114
5DYSASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal--2.32016-08-1010.15252/embr.201642671
5EN0ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)2.812016-08-1010.15252/embr.201642671
5EN0 (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-2.812016-08-1010.15252/embr.201642671
5DGYASensoryOpsinsRhodopsinHomo sapiens--Arrestin17.72016-03-2310.1038/sdata.2016.21
4X1HASensoryOpsinsRhodopsinBos taurusNonyl-β-D-Glucopyranoside-Gt(CT)2.292015-11-0410.1016/j.str.2015.09.015
4X1H (No Gprot) ASensoryOpsinsRhodopsinBos taurusNonyl-β-D-Glucopyranoside-2.292015-11-0410.1016/j.str.2015.09.015
4ZWJASensoryOpsinsRhodopsinHomo sapiens--Arrestin13.32015-07-2910.1038/nature14656
4WW3ASensoryOpsinsRhodopsinTodarodes pacificusAll-trans-Retinal--2.82015-06-1710.1371/journal.pone.0126970
4PXFASensoryOpsinsRhodopsinBos taurusOctyl-β-D-Glucopyranoside-Arrestin1 Finger Loop2.752014-09-1710.1038/ncomms5801
4J4QASensoryOpsinsRhodopsinBos taurusOctyl β-D-Glucopyranoside-Gt(CT)2.652013-10-3010.1002/anie.201302374
4J4Q (No Gprot) ASensoryOpsinsRhodopsinBos taurusOctyl β-D-Glucopyranoside-2.652013-10-3010.1002/anie.201302374
4BEYASensoryOpsinsRhodopsinBos taurus--Gt(CT)2.92013-05-0810.1038/embor.2013.44
4BEY (No Gprot) ASensoryOpsinsRhodopsinBos taurus--2.92013-05-0810.1038/embor.2013.44
4BEZASensoryOpsinsRhodopsinBos taurus---3.32013-04-2410.1038/embor.2013.44
4A4MASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)3.32012-01-2510.1073/pnas.1114089108
4A4M (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-3.32012-01-2510.1073/pnas.1114089108
3AYNASensoryOpsinsRhodopsinTodarodes pacificus9-cis-Retinal--2.72011-08-1710.1016/j.jmb.2011.08.044
3AYMASensoryOpsinsRhodopsinTodarodes pacificusAll-trans-Retinal--2.82011-08-1710.1016/j.jmb.2011.08.044
2X72ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)32011-03-1610.1038/nature09795
2X72 (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-32011-03-1610.1038/nature09795
3PXOASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal--32011-03-0910.1038/nature09789
3PQRASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-Gt(CT)2.852011-03-0910.1038/nature09789
3PQR (No Gprot) ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal-2.852011-03-0910.1038/nature09789
3OAXASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--2.62011-01-1910.1016/j.bpj.2010.08.003
3DQBASensoryOpsinsRhodopsinBos taurus--Gt(CT)3.22008-09-2310.1038/nature07330
3DQB (No Gprot) ASensoryOpsinsRhodopsinBos taurus--3.22008-09-2310.1038/nature07330
3C9MASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--3.42008-08-0510.1107/S0907444908017162
3C9LASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--2.652008-08-0510.1107/S0907444908017162
3CAPASensoryOpsinsRhodopsinBos taurus---2.92008-06-2410.1038/nature07063
3CAP (Multimeric) ASensoryOpsinsRhodopsinBos taurus--2.92008-06-2410.1038/nature07063
2Z73ASensoryOpsinsRhodopsinTodarodes pacificus11-cis-Retinal--2.52008-05-1310.1038/nature06925
2ZIYASensoryOpsinsRhodopsinTodarodes pacificus11-cis-Retinal--3.72008-05-0610.1074/jbc.C800040200
2PEDASensoryOpsinsRhodopsinBos taurus9-cis-Retinal--2.952007-10-3010.1529/biophysj.107.108225
2J4YASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--3.42007-09-2510.1016/j.jmb.2007.03.007
2I37ASensoryOpsinsRhodopsinBos taurus---4.152006-10-1710.1073/pnas.0608022103
2I36ASensoryOpsinsRhodopsinBos taurus---4.12006-10-1710.1073/pnas.0608022103
2I35ASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--3.82006-10-1710.1073/pnas.0608022103
2G87ASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal--2.62006-09-0210.1002/anie.200600595
2HPYASensoryOpsinsRhodopsinBos taurusAll-trans-Retinal--2.82006-08-2210.1073/pnas.0601765103
1U19ASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--2.22004-10-1210.1016/j.jmb.2004.07.044
1GZMASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--2.652003-11-2010.1016/j.jmb.2004.08.090
1L9HASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--2.62002-05-1510.1073/pnas.082666399
1HZXASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--2.82001-07-0410.1021/bi0155091
1F88ASensoryOpsinsRhodopsinBos taurus11-cis-Retinal--2.82000-08-0410.1126/science.289.5480.739




You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 7MT8_nogp.zip



You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.



You can also  read or  download a guide explaining the meaning of all files and numerical data.