psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	NT.D35	NT.N32	9.42	No	No	0	7	7
2	NT.D35	NT.N41	4.04	No	No	0	7	3
3	7x24	NT.C38	7.28	No	No	0	6	7
4	1x28	7x31	3.57	No	No	0	4	4
5	1x28	7x35	3.5	No	No	0	4	4
6	1x31	7x35	4.55	No	No	0	5	4
7	1x34	1x38	7.31	No	No	0	6	5
8	1x35	1x39	9.38	No	Yes	0	5	8
9	1x36	1x37	5.84	Yes	No	0	5	5
10	1x36	2x64	3.74	Yes	No	0	5	5
11	1x39	2x60	5.79	Yes	Yes	1	8	6
12	1x39	7x38	5.64	Yes	Yes	1	8	6
13	1x39	7x42	14.44	Yes	Yes	1	8	7
14	1x40	2x58	5.4	No	No	0	4	8
15	1x40	2x61	7.78	No	No	0	4	6
16	1x42	7x43	5.24	No	Yes	3	7	6
17	1x42	7x47	3.42	No	No	3	7	8
18	1x43	1x44	3.77	No	No	0	7	6
19	1x43	2x58	14.45	No	No	0	7	8
20	1x45	7x47	5.12	No	No	0	6	8
21	1x46	2x54	3.42	No	No	0	8	6
22	1x49	7x50	4.06	No	No	0	8	9
23	1x50	2x47	4.69	Yes	No	0	9	9
24	1x50	2x50	10.77	Yes	No	0	9	9
25	1x50	2x51	5.49	Yes	No	0	9	7
26	1x50	7x50	6.52	Yes	No	0	9	9
27	1x52	8x54	4.15	No	No	2	6	6
28	1x53	2x47	3.39	No	No	0	8	9
29	1x53	7x50	3.53	No	No	0	8	9
30	1x54	2x44	4.28	No	No	0	7	5
31	1x55	1x59	3.52	No	Yes	4	4	5
32	1x55	8x61	4.15	No	No	4	4	2
33	1x56	8x50	5.24	Yes	Yes	2	7	8
34	1x56	8x57	7.93	Yes	No	0	7	4
35	1x57	1x58	13.5	Yes	No	0	7	4
36	1x57	I1x51	23.89	Yes	No	0	7	7
37	1x57	2x44	17.58	Yes	No	0	7	5
38	1x57	Allo3	4.48	Yes	Yes	0	7	0
39	1x59	8x57	3.75	Yes	No	0	5	4
40	1x59	8x61	10.55	Yes	No	4	5	2
41	1x60	I1x49	4.18	No	Yes	2	6	6
42	1x60	I1x51	4.85	No	No	0	6	7
43	1x60	8x53	6.22	No	No	2	6	4
44	2x40	I1x49	10.72	No	Yes	2	8	6
45	8x49	I1x49	14.93	No	Yes	2	6	6
46	8x53	I1x49	15.48	No	Yes	2	4	6
47	Allo3	I1x49	3.32	Yes	Yes	2	0	6
48	2x37	2x40	10.12	No	No	2	7	8
49	2x37	Allo3	4.83	No	Yes	2	7	0
50	2x38	3x49	6.18	No	Yes	0	6	8
51	2x38	4x42	3.42	No	Yes	0	6	7
52	2x39	3x49	7.23	No	Yes	2	8	8
53	2x39	3x50	11.64	No	Yes	2	8	9
54	2x39	Allo3	7.25	No	Yes	2	8	0
55	2x40	Allo3	14.09	No	Yes	2	8	0
56	2x41	2x45	5.61	Yes	No	5	7	9
57	2x41	4x42	6.13	Yes	Yes	0	7	7
58	2x41	4x43	5.76	Yes	No	0	7	3
59	2x41	4x46	4.86	Yes	No	5	7	7
60	2x42	3x45	11.17	Yes	No	0	7	7
61	2x42	3x46	5.02	Yes	No	0	7	8
62	2x42	4x42	5.28	Yes	Yes	0	7	7
63	2x42	4x45	3.93	Yes	No	0	7	6
64	2x43	7x53	5.86	No	Yes	2	8	9
65	2x43	Allo3	15.13	No	Yes	2	8	0
66	2x44	2x48	4.28	No	No	0	5	6
67	2x45	4x46	11.02	No	No	5	9	7
68	2x45	4x50	7.91	No	No	0	9	9
69	2x46	3x42	4.15	No	No	0	9	8
70	2x48	4x50	3.52	No	No	0	6	9
71	2x50	3x35	5.39	No	Yes	1	9	8
72	2x50	7x46	5.89	No	Yes	1	9	9
73	2x53	2x57	4.87	Yes	No	0	7	8
74	2x53	3x32	4.13	Yes	Yes	1	7	7
75	2x53	3x35	4.83	Yes	Yes	1	7	8
76	2x53	7x42	13.93	Yes	Yes	1	7	7
77	2x53	7x46	7.93	Yes	Yes	1	7	9
78	2x54	7x46	6.01	No	Yes	0	6	9
79	2x56	3x28	4.76	No	No	0	7	5
80	2x59	3x24	7.46	No	Yes	0	7	6
81	2x60	3x24	3.49	Yes	Yes	0	6	6
82	2x60	3x28	11.03	Yes	No	0	6	5
83	2x60	7x38	8.76	Yes	Yes	1	6	6
84	3x24	3x27	4.56	Yes	No	0	6	5
85	3x30	4x62	4.64	No	No	0	5	5
86	3x32	3x33	3.58	Yes	No	0	7	5
87	3x32	3x36	6.19	Yes	Yes	1	7	8
88	3x32	6x48	9.02	Yes	Yes	1	7	9
89	3x32	6x51	12.91	Yes	Yes	1	7	7
90	3x32	6x52	5.81	Yes	No	1	7	8
91	3x32	7x41	4	Yes	No	1	7	8
92	3x32	7x42	6.19	Yes	Yes	1	7	7
93	3x33	3x37	10.75	No	No	0	5	7
94	3x33	4x61	12.15	No	No	0	5	4
95	3x34	4x57	3.24	No	No	0	5	6
96	3x35	3x39	4.72	Yes	No	0	8	9
97	3x35	7x46	4.47	Yes	Yes	1	8	9
98	3x36	3x37	4.13	Yes	No	0	8	7
99	3x36	3x40	5.24	Yes	No	0	8	8
100	3x36	5x50	5.78	Yes	No	0	8	9
101	3x36	6x44	3.22	Yes	Yes	1	8	9
102	3x36	6x48	8.2	Yes	Yes	1	8	9
103	3x36	6x52	14.5	Yes	No	1	8	8
104	3x37	4x56	11.72	No	No	0	7	6
105	3x38	4x53	3.42	No	No	0	7	8
106	3x39	6x44	5.59	No	Yes	0	9	9
107	3x40	5x53	3.21	No	No	0	8	7
108	3x41	4x49	9.99	No	No	0	6	7
109	3x42	4x49	4.28	No	No	0	8	7
110	3x43	6x44	5.02	No	Yes	0	8	9
111	3x44	5x53	4.56	No	No	0	7	7
112	3x44	5x57	3.24	No	No	0	7	7
113	3x47	5x57	3.64	No	No	0	9	7
114	3x47	5x60	3.27	No	No	0	9	3
115	3x47	5x61	3.27	No	No	0	9	8
116	3x49	3x50	5.96	Yes	Yes	2	8	9
117	3x49	4x38	11.91	Yes	No	0	8	7
118	3x50	3x53	5.53	Yes	No	0	9	8
119	3x50	6x37	6.47	Yes	No	2	9	7
120	3x50	Allo3	11.95	Yes	Yes	2	9	0
121	3x51	3x55	4	Yes	No	0	8	7
122	3x51	3x56	4.51	Yes	No	0	8	7
123	3x51	5x64	9.99	Yes	No	0	8	5
124	3x51	5x67	10.15	Yes	No	0	8	4
125	3x52	I2x52	3.76	No	No	0	5	5
126	3x54	6x33	3.25	No	No	0	8	8
127	3x54	6x34	4.28	No	No	0	8	6
128	3x56	I2x52	3.5	No	No	0	7	5
129	I2x52	I2x56	14.99	No	No	0	5	4
130	4x38	I2x53	5.53	No	No	0	7	5
131	4x35	I2x54	15.8	No	No	0	4	5
132	I2x55	I2x56	12.13	No	No	0	5	4
133	4x37	I2x56	6.96	No	No	0	6	4
134	4x36	4x37	13.5	No	No	0	3	6
135	4x47	4x51	5.24	No	No	0	4	4
136	4x56	5x46	4.15	No	No	0	6	5
137	4x59	4x60	5.08	No	No	0	4	7
138	5x39	5x43	6.07	No	No	0	5	5
139	5x40	6x63	12.89	No	Yes	0	5	1
140	5x43	6x63	3.58	No	Yes	0	5	1
141	5x47	6x56	12.18	Yes	No	0	8	6
142	5x47	6x59	3.89	Yes	No	0	8	5
143	5x48	5x52	7.87	No	No	0	5	3
144	5x54	6x45	6.09	No	No	0	8	5
145	5x57	6x41	6.35	No	No	0	7	8
146	5x58	6x41	15.24	No	No	0	8	8
147	5x58	6x42	6.24	No	No	0	8	5
148	5x58	6x45	3.79	No	No	0	8	5
149	5x61	6x38	4.42	No	No	0	8	5
150	5x68	6x30	4.82	No	No	0	6	7
151	6x29	I3.K246	4.59	No	No	0	4	4
152	6x30	6x31	9.17	No	No	0	7	6
153	6x32	8x48	6.75	No	No	0	7	4
154	6x34	6x37	4.42	No	No	0	6	7
155	6x35	7x56	6.07	No	No	0	5	7
156	6x36	Allo3	8.61	No	Yes	0	8	0
157	6x37	Allo3	7.25	No	Yes	2	7	0
158	6x39	7x56	9.52	No	No	0	6	7
159	6x40	7x49	5.91	No	No	0	8	9
160	6x40	Allo3	4.07	No	Yes	0	8	0
161	6x43	7x45	5.54	No	Yes	0	7	9
162	6x43	7x52	5.96	No	No	0	7	8
163	6x44	6x48	7.03	Yes	Yes	1	9	9
164	6x44	7x45	9.05	Yes	Yes	1	9	9
165	6x47	6x48	7.22	No	Yes	1	9	9
166	6x47	7x45	11.16	No	Yes	1	9	9
167	6x48	7x41	4.55	Yes	No	1	9	8
168	6x48	7x45	3.71	Yes	Yes	1	9	9
169	6x49	6x50	4.33	No	No	0	6	9
170	6x49	6x53	8.38	No	No	0	6	7
171	6x50	7x37	3.5	No	No	0	9	6
172	6x51	6x55	16.41	Yes	No	0	7	6
173	6x51	7x34	6.19	Yes	Yes	1	7	4
174	6x51	7x37	6.24	Yes	No	0	7	6
175	6x51	7x38	16.91	Yes	Yes	1	7	6
176	6x51	7x41	4	Yes	No	1	7	8
177	6x54	7x33	3.27	No	No	0	5	5
178	6x54	7x37	4.56	No	No	0	5	6
179	6x56	6x60	4.28	No	No	0	6	4
180	6x58	7x34	12.88	No	Yes	0	4	4
181	6x60	E3.F285	3.77	No	Yes	0	4	1
182	6x61	E3.F285	15.52	No	Yes	6	2	1
183	6x61	E3.I286	13.99	No	Yes	6	2	2
184	E3.F285	E3.I286	5.02	Yes	Yes	6	1	2
185	7x26	E3.I286	4.61	No	Yes	0	1	2
186	7x23	7x26	5.91	No	No	0	3	1
187	7x34	7x35	3.51	Yes	No	0	4	4
188	7x34	7x38	5.86	Yes	Yes	1	4	6
189	7x38	7x42	14.05	Yes	Yes	1	6	7
190	7x43	7x47	4.19	Yes	No	3	6	8
191	7x43	7x48	7.31	Yes	No	0	6	7
192	7x45	7x49	5.1	Yes	No	0	9	9
193	7x49	7x53	10.47	No	Yes	0	9	9
194	7x53	8x50	5.16	Yes	Yes	2	9	8
195	7x53	Allo3	10.89	Yes	Yes	2	9	0
196	8x47	Allo3	3.74	No	Yes	0	8	0
197	8x49	8x53	5.96	No	No	2	6	4
198	8x49	Allo3	14.6	No	Yes	2	6	0
199	8x50	Allo3	11.31	Yes	Yes	2	8	0
200	8x55	8x59	4.55	No	No	0	5	5
201	2x46	3x39	3.17	No	No	0	9	9
202	NT.F33	NT.Y37	3.09	No	No	0	4	2
203	NT.F36	NT.Y37	3.09	No	No	0	3	2
204	1x27	7x32	3.07	No	No	0	3	1
205	3x54	5x64	3.04	No	No	0	8	5
206	6x33	8x48	3.02	No	No	0	8	4
207	2x56	3x31	3.01	No	No	0	7	5
208	5x461	5x47	3.01	No	Yes	0	6	8
209	1x51	2x51	3	No	No	0	4	7
210	4x39	4x42	3	No	Yes	0	3	7
211	1x41	1x45	2.98	No	No	0	4	6
212	1x42	2x57	2.98	No	No	0	7	8
213	1x52	1x56	2.98	No	Yes	2	6	7
214	1x56	8x54	2.98	Yes	No	2	7	6
215	5x40	5x44	2.98	No	No	0	5	6
216	7x23	E3.S287	2.98	No	No	0	3	1
217	6x39	7x52	2.95	No	No	0	6	8
218	6x42	6x46	2.95	No	No	0	5	5
219	5x62	5x66	2.94	No	No	0	5	4
220	3x31	3x34	2.89	No	No	0	5	5
221	2x52	3x31	2.83	No	No	0	7	5
222	8x60	8x64	2.83	No	No	0	4	3
223	5x65	6x30	2.82	No	No	0	8	7
224	3x41	4x52	2.77	No	No	0	6	4
225	5x65	6x34	2.77	No	No	0	8	6
226	5x59	5x63	2.74	No	No	0	4	3
227	6x58	7x30	2.74	No	No	0	4	4
228	6x62	6x63	2.67	No	Yes	0	3	1
229	7x51	7x55	2.62	No	No	0	6	6
230	7x54	8x50	2.62	No	Yes	0	7	8
231	2x49	4x50	2.59	No	No	0	8	9
232	1x38	7x43	2.44	No	Yes	0	5	6
233	5x47	6x55	2.44	Yes	No	0	8	6
234	1x59	8x64	2.42	Yes	No	0	5	3
235	5x36	6x63	2.39	No	Yes	0	3	1
236	1x36	2x65	1.87	Yes	No	0	5	4
237	8x62	8x65	1.86	No	No	0	4	5
238	1x32	2x65	1.71	No	No	0	6	4
239	1x48	1x49	1.71	No	No	0	5	8
240	2x49	3x38	1.71	No	No	0	8	7
241	5x52	5x56	1.71	No	No	0	3	5
242	7x24	7x28	1.69	No	No	0	6	2
243	7x25	7x28	1.68	No	No	0	1	2
244	1x35	1x36	1.64	No	Yes	0	5	5
245	2x57	2x58	1.64	No	No	0	8	8
246	5x49	5x50	1.64	No	No	0	6	9
247	6x60	6x64	1.62	No	No	0	4	3
248	3x34	4x54	1.61	No	No	0	5	3
249	2x55	2x56	1.59	No	No	0	5	7
250	1x38	7x39	1.58	No	No	0	5	5
251	1x47	2x51	1.58	No	No	0	6	7
252	3x25	3x29	1.57	No	No	0	9	5
253	8x60	I1x48	1.56	No	No	0	4	6
254	6x47	7x40	1.55	No	No	0	9	8
255	7x27	E3.I286	1.55	No	Yes	0	3	2
256	3x48	3x52	1.54	No	No	0	6	5
257	3x48	5x60	1.54	No	No	0	6	3
258	7x32	7x36	1.54	No	No	0	1	5
259	7x36	7x40	1.54	No	No	0	5	8
260	I2x51	I2x55	1.51	No	No	0	6	5
261	5x34	E2.T208	1.5	No	No	0	1	1
262	5x35	5x39	1.49	No	No	0	3	5
263	5x44	6x56	1.49	No	No	0	6	6
264	4x59	4x62	1.47	No	No	0	4	5
265	4x40	4x44	1.41	No	No	0	4	2
266	1x29	NT.N41	1.32	No	No	0	2	3
267	2x60	3x25	1.31	Yes	No	0	6	9
268	3x29	4x61	1.31	No	No	0	5	4
269	5x51	5x52	1.31	No	No	0	7	3
270	6x57	E3.F285	1.31	No	Yes	0	5	1
271	7x54	7x55	1.31	No	No	0	7	6
272	7x55	7x56	1.31	No	No	0	6	7
273	NT.D35	NT.E34	1.3	No	No	0	7	6
274	5x45	5x48	1.26	No	No	0	5	5
275	3x23	3x24	1.24	No	Yes	0	3	6
276	5x63	5x67	1.24	No	No	0	3	4
277	4x41	4x44	1.2	No	No	0	3	2
278	1x40	2x62	1.17	No	No	0	4	4
279	4x35	4x38	1.07	No	No	0	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	1x36	3.2725	4	0	5
2	1x39	8.8125	4	1	8
3	1x50	6.8675	4	0	9
4	1x56	4.7825	4	2	7
5	1x57	14.8625	4	0	7
6	1x59	5.06	4	4	5
7	I1x49	9.726	5	2	6
8	2x41	5.59	4	5	7
9	2x42	6.35	4	0	7
10	2x53	7.138	5	1	7
11	2x60	6.076	5	1	6
12	3x24	4.1875	4	0	6
13	3x32	6.47875	8	1	7
14	3x35	4.8525	4	1	8
15	3x36	6.75143	7	1	8
16	3x49	7.82	4	2	8
17	3x50	8.31	5	2	9
18	3x51	7.1625	4	0	8
19	4x42	4.4575	4	0	7
20	5x47	5.38	4	0	8
21	6x44	5.982	5	1	9
22	6x48	6.62167	6	1	9
23	6x51	10.4433	6	1	7
24	6x63	5.3825	4	0	1
25	E3.F285	6.405	4	6	1
26	E3.I286	6.2925	4	6	2
27	7x34	7.11	4	1	4
28	7x38	10.244	5	1	6
29	7x42	12.1525	4	1	7
30	7x43	4.795	4	3	6
31	7x45	6.912	5	1	9
32	7x46	6.075	4	1	9
33	7x53	8.095	4	2	9
34	8x50	6.0825	4	2	8
35	Allo3	8.68	14	2	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	3x32	6x51	35.3365	12.91	Yes	Yes	1	7	7
2	2x53	3x32	18.8565	4.13	Yes	Yes	1	7	7
3	2x53	2x57	14.0457	4.87	Yes	No	0	7	8
4	7x38	7x42	11.4327	14.05	Yes	Yes	1	6	7
5	2x50	3x35	10.3785	5.39	No	Yes	1	9	8
6	1x50	2x50	13.2466	10.77	Yes	No	0	9	9
7	3x32	6x48	54.5846	9.02	Yes	Yes	1	7	9
8	6x48	7x45	83.0599	3.71	Yes	Yes	1	9	9
9	7x45	7x49	100	5.1	Yes	No	0	9	9
10	7x49	7x53	54.6609	10.47	No	Yes	0	9	9
11	6x51	7x41	24.8186	4	Yes	No	1	7	8
12	6x48	7x41	25.2208	4.55	Yes	No	1	9	8
13	6x40	7x49	45.1577	5.91	No	No	0	8	9
14	6x40	Allo3	44.7503	4.07	No	Yes	0	8	0
15	1x57	Allo3	17.1293	4.48	Yes	Yes	0	7	0
16	1x57	2x44	12.918	17.58	Yes	No	0	7	5
17	7x53	Allo3	44.7266	10.89	Yes	Yes	2	9	0
18	2x39	Allo3	21.6719	7.25	No	Yes	2	8	0
19	2x39	3x49	20.3654	7.23	No	Yes	2	8	8
20	2x38	3x49	28.1467	6.18	No	Yes	0	6	8
21	3x50	Allo3	22.9784	11.95	Yes	Yes	2	9	0
22	3x49	3x50	21.6193	5.96	Yes	Yes	2	8	9
23	2x38	4x42	25.3707	3.42	No	Yes	0	6	7
24	2x44	2x48	10.0683	4.28	No	No	0	5	6
25	2x42	4x42	11.3644	5.28	Yes	Yes	0	7	7
26	3x32	3x36	11.622	6.19	Yes	Yes	1	7	8
27	3x36	6x44	10.765	3.22	Yes	Yes	1	8	9
28	3x39	6x44	13.3833	5.59	No	Yes	0	9	9
29	2x60	7x38	25.6651	8.76	Yes	Yes	1	6	6
30	2x60	3x28	20.6283	11.03	Yes	No	0	6	5
31	2x56	3x28	18.0678	4.76	No	No	0	7	5
32	2x60	3x24	10.3549	3.49	Yes	Yes	0	6	6
33	2x56	3x31	12.9311	3.01	No	No	0	7	5
34	3x36	3x40	20.3523	5.24	Yes	No	0	8	8
35	3x40	5x53	19.1299	3.21	No	No	0	8	7
36	3x44	5x53	17.9154	4.56	No	No	0	7	7
37	3x44	5x57	16.7482	3.24	No	No	0	7	7
38	3x49	4x38	11.3959	11.91	Yes	No	0	8	7
39	6x37	Allo3	22.5789	7.25	No	Yes	2	7	0
40	6x34	6x37	22.7445	4.42	No	No	0	6	7
41	3x54	6x34	16.5142	4.28	No	No	0	8	6
42	3x54	5x64	11.4905	3.04	No	No	0	8	5
43	3x51	5x64	10.234	9.99	Yes	No	0	8	5
44	6x51	6x55	30.1656	16.41	Yes	No	0	7	6
45	5x47	6x55	28.9012	2.44	Yes	No	0	8	6
46	5x47	6x56	25.0868	12.18	Yes	No	0	8	6
47	5x44	6x56	10.7781	1.49	No	No	0	6	6
48	6x56	6x60	13.4437	4.28	No	No	0	6	4
49	6x60	E3.F285	10.7781	3.77	No	Yes	0	4	1
50	1x39	7x42	14.6477	14.44	Yes	Yes	1	8	7
51	1x39	2x60	10.0289	5.79	Yes	Yes	1	8	6
52	3x32	7x42	20.9989	6.19	Yes	Yes	1	7	7
53	6x51	7x38	17.3817	16.91	Yes	Yes	1	7	6
54	6x44	7x45	18.5147	9.05	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
1x56	8x50	5.24	2	Yes	Yes	7	8	2	1
1x57	1x58	13.5	0	Yes	No	7	4	1	2
1x57	I1x51	23.89	0	Yes	No	7	7	1	2
1x57	2x44	17.58	0	Yes	No	7	5	1	2
1x57	Allo3	4.48	0	Yes	Yes	7	0	1	0
1x60	I1x49	4.18	2	No	Yes	6	6	2	1
1x60	I1x51	4.85	2	No	No	6	7	2	2
1x60	8x53	6.22	2	No	No	6	4	2	2
2x40	I1x49	10.72	2	No	Yes	8	6	1	1
8x49	I1x49	14.93	2	No	Yes	6	6	1	1
8x53	I1x49	15.48	2	No	Yes	4	6	2	1
Allo3	I1x49	3.32	2	Yes	Yes	0	6	0	1
2x37	2x40	10.12	2	No	No	7	8	1	1
2x37	Allo3	4.83	2	No	Yes	7	0	1	0
2x39	3x49	7.23	2	No	Yes	8	8	1	2
2x39	3x50	11.64	2	No	Yes	8	9	1	1
2x39	Allo3	7.25	2	No	Yes	8	0	1	0
2x40	Allo3	14.09	2	No	Yes	8	0	1	0
2x43	7x53	5.86	2	No	Yes	8	9	1	1
2x43	Allo3	15.13	2	No	Yes	8	0	1	0
3x49	3x50	5.96	2	Yes	Yes	8	9	2	1
3x50	3x53	5.53	2	Yes	No	9	8	1	2
3x50	6x37	6.47	2	Yes	No	9	7	1	1
3x50	Allo3	11.95	2	Yes	Yes	9	0	1	0
6x34	6x37	4.42	0	No	No	6	7	2	1
6x36	Allo3	8.61	0	No	Yes	8	0	1	0
6x37	Allo3	7.25	2	No	Yes	7	0	1	0
6x40	7x49	5.91	0	No	No	8	9	1	2
6x40	Allo3	4.07	0	No	Yes	8	0	1	0
7x49	7x53	10.47	0	No	Yes	9	9	2	1
7x53	8x50	5.16	2	Yes	Yes	9	8	1	1
7x53	Allo3	10.89	2	Yes	Yes	9	0	1	0
8x47	Allo3	3.74	0	No	Yes	8	0	1	0
8x49	8x53	5.96	2	No	No	6	4	1	2
8x49	Allo3	14.6	2	No	Yes	6	0	1	0
8x50	Allo3	11.31	2	Yes	Yes	8	0	1	0
7x54	8x50	2.62	0	No	Yes	7	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	5LWE	Vercirnon	5LWE-CCR9-Vercirnon
73.33	Single	6LFL	PubChem 153466996	6LFL-CXCR2-PubChem 153466996
57.14	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
47.06	Single	6QZH	HY-133073; Na	6QZH-CCR7-HY-133073; Na
47.06	Consensus	ccr7_off_allo	Other Ligand	6QZH-CCR7-HY-133073; Na
41.18	Single	5X7D	PubChem 129318963	5X7D-β₂-(S)-Carazolol-PubChem 129318963
38.89	Single	8JPF	PubChem 118610427	8JPF-NTS₁-Neurotensin-PubChem 118610427
36.84	Single	8JPC	PubChem 118610427; GDP; Mg	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
35.71	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
30.00	Single	8FN0	PubChem 118610427	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
28.57	Single	8JPB	PubChem 118610427; GDP; Mg	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
27.78	Consensus	nts1_on_allo	Other Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
21.74	Single	8TB7	PubChem 168510218	8TB7-GPR61-PubChem 168510218
21.05	Single	6KK1	PubChem 68178630	6KK1-GLP-1-PubChem 68178630
20.00	Single	3VG9	Antibody	3VG9-A_2A-ZM241385-Antibody
19.05	Single	8JR9	PCO371	8JR9-PTH1-PCO371-chim(NtGi1-Gs)/&β;1/&γ;2
18.75	Single	3VGA	Antibody	3VGA-A_2A-ZM241385-Antibody
18.18	Single	8GW8	KHF	8GW8-PTH1-KHF-Gs/&β;1/&γ;2
13.04	Single	5XF1	NNC0640	5XF1-Glucagon-NNC0640
12.50	Single	4PXF	Octyl Beta-D-Glucopyranoside	4PXF-Rhodopsin-Octyl Beta-D-Glucopyranoside-Arrestin1_Finger_loop
10.00	Single	5VEX	NNC0640	5VEX-GLP-1-NNC0640
10.00	Single	6KK7	PubChem 68178630	6KK7-GLP-1-PubChem 68178630
9.52	Single	6KJV	PubChem 68178630	6KJV-GLP-1-PubChem 68178630
9.09	Single	5VEW	PF-06372222	5VEW-GLP-1-PF-06372222
8.70	Single	5XEZ	NNC0640	5XEZ-Glucagon-NNC0640
8.33	Consensus	ffa3_on_allo	Other Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
8.00	Single	6LN2	PubChem 68178630	6LN2-GLP-1-PubChem 68178630
8.00	Single	8J20	AR420626	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
5.26	Single	7EB2	rac-BHFF	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.26	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
5.26	Consensus	gabab_on	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.26	Consensus	gi_class-c	Other Ligand	gi_mglu gi_gaba
5.00	Consensus	gi_gaba	Other Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
4.76	Single	7CA3	rac-BHFF	7CA3-GABA_B1, GABA_B2-rac-BHFF
4.55	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
4.55	Single	7C7Q	PubChem 7023848	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
4.35	Single	7EJX	(1R;2R)-2-PCCA	7EJX-GPR88-(1R;2R)-2-PCCA-Gi1/&β;1/&γ;2
4.17	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
4.17	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
4.00	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
3.70	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
3.57	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2

Consensus Members
	Id	Members
	5LWE	5LWE-CCR9-Vercirnon

Net Summary
I_min	3.21
Number of Linked Nodes	254
Number of Links	279
Number of Hubs	35
Number of Links mediated by Hubs	134
Number of Communities	6
Number of Nodes involved in Communities	47
Number of Links involved in Communities	70

Path Summary
Number Of Nodes in MetaPath	55
Number Of Links MetaPath	54
Number of Shortest Paths	60163
Length Of Smallest Path	3
Average Path Length	12.5792
Length of Longest Path	24
Minimum Path Strength	1.305
Average Path Strength	6.55975
Maximum Path Strength	20.735
Minimum Path Correlation	0.7
Average Path Correlation	0.935863
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.88235
Average % Of Corr. Nodes	56.0624
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	48.6812
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download ccr9_off_allo.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.