psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:S78	4.13	Yes	No	0	0	8
2	L:L:?1	R:R:Y386	14.51	Yes	No	0	0	8
3	L:L:?1	R:R:D410	15.86	Yes	No	0	0	9
4	L:L:?1	R:R:H411	18.56	Yes	No	0	0	4
5	R:R:F19	R:R:L18	6.09	Yes	No	0	1	1
6	R:R:F19	R:R:I24	5.02	Yes	No	0	1	7
7	R:R:F19	R:R:M27	2.49	Yes	No	0	1	6
8	R:R:F19	R:R:Q85	4.68	Yes	No	0	1	5
9	R:R:P21	R:R:Q20	3.16	No	No	3	5	4
10	R:R:Q20	R:R:Q22	11.52	No	No	3	4	4
11	R:R:D23	R:R:Q20	7.83	No	No	3	4	4
12	R:R:P21	R:R:Q22	4.74	No	No	3	5	4
13	R:R:D23	R:R:Q22	2.61	No	No	3	4	4
14	R:R:D23	R:R:S26	2.94	No	Yes	0	4	8
15	R:R:I29	R:R:L30	2.85	No	Yes	0	7	6
16	R:R:A415	R:R:I29	3.25	No	No	0	9	7
17	R:R:L30	R:R:L75	5.54	Yes	No	0	6	8
18	R:R:L30	R:R:S418	3	Yes	No	0	6	9
19	R:R:A419	R:R:T33	3.36	No	No	0	8	9
20	R:R:C422	R:R:T33	3.38	No	No	0	8	9
21	R:R:F69	R:R:L38	2.44	Yes	No	0	7	7
22	R:R:C72	R:R:L38	3.17	No	No	0	8	7
23	R:R:D68	R:R:N41	4.04	Yes	No	0	9	9
24	R:R:F69	R:R:N41	4.83	Yes	No	0	7	9
25	R:R:N41	R:R:P425	4.89	No	No	0	9	9
26	R:R:F69	R:R:G42	3.01	Yes	No	0	7	6
27	R:R:T65	R:R:V44	6.35	No	No	0	9	9
28	R:R:F435	R:R:V44	5.24	Yes	No	0	9	9
29	R:R:V50	R:R:W46	13.48	No	No	0	6	8
30	R:R:F435	R:R:V47	3.93	Yes	No	0	9	8
31	R:R:K51	R:R:V50	4.55	No	No	0	9	6
32	R:R:K51	R:R:M52	2.88	No	No	0	9	9
33	R:R:K51	R:R:S442	3.06	No	No	0	9	9
34	R:R:K438	R:R:M52	7.2	No	No	0	7	9
35	R:R:N57	R:R:T55	5.85	No	No	6	8	9
36	R:R:T55	R:R:T58	9.42	No	No	6	9	9
37	R:R:N57	R:R:T58	4.39	No	No	6	8	9
38	R:R:H63	R:R:V59	2.77	Yes	Yes	0	8	7
39	R:R:A139	R:R:V59	3.39	No	Yes	0	8	7
40	R:R:I116	R:R:W60	4.7	No	Yes	0	9	8
41	R:R:D119	R:R:W60	4.47	No	Yes	0	9	8
42	R:R:A139	R:R:W60	2.59	No	Yes	0	8	8
43	R:R:I142	R:R:W60	5.87	No	Yes	0	5	8
44	R:R:C143	R:R:W60	5.22	No	Yes	0	8	8
45	R:R:H63	R:R:L112	2.57	Yes	No	0	8	9
46	R:R:C143	R:R:H63	16.22	No	Yes	0	8	8
47	R:R:H63	R:R:W147	7.41	Yes	Yes	0	8	9
48	R:R:D68	R:R:L64	2.71	Yes	No	5	9	9
49	R:R:L64	R:R:S109	3	No	No	5	9	9
50	R:R:L113	R:R:L64	4.15	No	No	0	9	9
51	R:R:A67	R:R:W147	2.59	No	Yes	0	9	9
52	R:R:D68	R:R:S109	5.89	Yes	No	5	9	9
53	R:R:D68	R:R:S421	11.78	Yes	No	0	9	9
54	R:R:D68	R:R:N424	5.39	Yes	No	0	9	9
55	R:R:F69	R:R:L73	9.74	Yes	No	0	7	8
56	R:R:L70	R:R:N105	8.24	No	No	0	5	9
57	R:R:C71	R:R:S74	3.44	No	No	0	8	9
58	R:R:L75	R:R:P76	3.28	No	No	0	8	9
59	R:R:H81	R:R:S78	4.18	Yes	No	0	8	8
60	R:R:I83	R:R:L79	5.71	No	No	0	5	6
61	R:R:H81	R:R:W88	6.35	Yes	Yes	2	8	9
62	R:R:H81	R:R:I98	3.98	Yes	No	2	8	8
63	R:R:H87	R:R:L84	2.57	No	No	0	6	8
64	R:R:L84	R:R:P89	3.28	No	No	0	8	8
65	R:R:H87	R:R:R169	7.9	No	No	0	6	3
66	R:R:P89	R:R:W88	5.4	No	Yes	2	8	9
67	R:R:W88	R:R:Y90	14.47	Yes	No	2	9	8
68	R:R:C95	R:R:W88	3.92	No	Yes	0	9	9
69	R:R:I98	R:R:W88	3.52	No	Yes	2	8	9
70	R:R:S170	R:R:W88	3.71	No	Yes	0	3	9
71	R:R:P89	R:R:Y90	19.47	No	No	2	8	8
72	R:R:L94	R:R:Y90	10.55	No	No	0	8	8
73	R:R:K96	R:R:L92	4.23	No	No	0	9	2
74	R:R:L163	R:R:L92	5.54	No	No	0	6	2
75	R:R:F93	R:R:L97	3.65	No	No	0	4	6
76	R:R:C95	R:R:L163	4.76	No	No	0	9	6
77	R:R:C172	R:R:C95	7.28	No	No	0	9	9
78	R:R:F158	R:R:K96	14.89	No	No	0	8	9
79	R:R:K96	R:R:R161	9.9	No	No	0	9	8
80	R:R:I101	R:R:L97	5.71	No	No	0	6	6
81	R:R:I98	R:R:P99	6.77	No	No	0	8	8
82	R:R:S100	R:R:V157	6.46	No	No	0	8	8
83	R:R:F158	R:R:S100	6.61	No	No	0	8	8
84	R:R:I101	R:R:N105	2.83	No	No	0	6	9
85	R:R:F107	R:R:I103	5.02	Yes	No	4	8	5
86	R:R:I103	R:R:R333	12.53	No	Yes	4	5	9
87	R:R:L104	R:R:N105	2.75	Yes	No	0	7	9
88	R:R:F151	R:R:L104	4.87	No	Yes	8	6	7
89	R:R:C154	R:R:L104	6.35	No	Yes	8	7	7
90	R:R:M106	R:R:W383	4.65	No	Yes	0	9	9
91	R:R:M106	R:R:Y386	2.39	No	No	0	9	8
92	R:R:F107	R:R:F111	3.22	Yes	No	0	8	8
93	R:R:F107	R:R:M153	2.49	Yes	No	4	8	8
94	R:R:F107	R:R:R333	4.28	Yes	Yes	4	8	9
95	R:R:A108	R:R:W147	3.89	No	Yes	0	9	9
96	R:R:P341	R:R:V110	3.53	Yes	No	0	9	9
97	R:R:V110	R:R:W383	6.13	No	Yes	0	9	9
98	R:R:F111	R:R:V149	2.62	No	No	0	8	4
99	R:R:F111	R:R:V336	2.62	No	No	0	8	4
100	R:R:L112	R:R:V146	4.47	No	No	0	9	8
101	R:R:L113	R:R:N424	6.87	No	No	0	9	9
102	R:R:L113	R:R:Y428	5.86	No	Yes	0	9	9
103	R:R:S117	R:R:T114	3.2	No	No	0	9	8
104	R:R:P341	R:R:T114	3.5	Yes	No	0	9	8
105	R:R:I344	R:R:T114	4.56	No	No	0	6	8
106	R:R:I116	R:R:R120	3.76	No	No	0	9	9
107	R:R:M345	R:R:S117	4.6	No	No	0	7	9
108	R:R:C348	R:R:S117	3.44	No	No	0	8	9
109	R:R:C348	R:R:L118	3.17	No	No	0	8	8
110	R:R:D119	R:R:R134	10.72	No	No	0	9	9
111	R:R:R120	R:R:Y349	7.2	No	No	0	9	8
112	R:R:R120	R:R:Y428	5.14	No	Yes	0	9	9
113	R:R:C121	R:R:C348	7.28	No	No	0	8	8
114	R:R:C121	R:R:L351	3.17	No	No	0	8	6
115	R:R:C121	R:R:I352	3.27	No	No	0	8	9
116	R:R:C130	R:R:L122	3.17	No	No	0	8	7
117	R:R:I123	R:R:V124	3.07	No	No	0	5	9
118	R:R:I123	R:R:R134	6.26	No	No	0	5	9
119	R:R:R355	R:R:V124	2.62	No	No	0	7	9
120	R:R:H125	R:R:L351	7.71	No	No	0	6	6
121	R:R:H125	R:R:R355	4.51	No	No	0	6	7
122	R:R:H133	R:R:W129	11.64	No	No	0	8	8
123	R:R:C130	R:R:R134	2.79	No	No	0	8	9
124	R:R:N132	R:R:Q131	3.96	No	No	0	8	9
125	R:R:H133	R:R:N132	3.83	No	No	0	8	8
126	R:R:N135	R:R:R137	3.62	No	No	0	5	6
127	R:R:N135	R:R:T138	7.31	No	No	0	5	6
128	R:R:C154	R:R:F151	4.19	No	No	8	7	6
129	R:R:M153	R:R:T332	4.52	No	No	0	8	7
130	R:R:M153	R:R:R333	2.48	No	Yes	4	8	9
131	R:R:P156	R:R:V155	3.53	No	No	0	9	5
132	R:R:R161	R:R:V157	6.54	No	No	0	8	8
133	R:R:R333	R:R:V157	2.62	Yes	No	0	9	8
134	R:R:Y160	R:R:Y174	13.9	No	No	0	8	8
135	R:R:R161	R:R:Y174	5.14	No	No	0	8	8
136	R:R:D162	R:R:F164	11.94	No	No	0	6	2
137	R:R:F164	R:R:R173	3.21	No	No	0	2	1
138	R:R:D167	R:R:R169	3.57	No	No	0	3	3
139	R:R:I171	R:R:R173	2.51	No	No	0	1	1
140	R:R:L326	R:R:Y174	5.86	No	No	0	3	8
141	R:R:L394	R:R:V322	4.47	No	No	0	7	3
142	R:R:P323	R:R:P325	3.9	No	No	0	2	4
143	R:R:L326	R:R:P323	6.57	No	No	0	3	2
144	R:R:P325	R:R:T324	3.5	No	No	0	4	5
145	R:R:I331	R:R:T330	3.04	No	No	0	6	8
146	R:R:L394	R:R:T330	2.95	No	No	0	7	8
147	R:R:F338	R:R:L334	2.44	Yes	No	1	9	7
148	R:R:H387	R:R:L334	2.57	No	No	1	9	7
149	R:R:L334	R:R:V391	4.47	No	No	0	7	7
150	R:R:V335	R:R:V336	3.21	No	No	0	7	4
151	R:R:G337	R:R:P341	4.06	No	Yes	0	9	9
152	R:R:F338	R:R:F380	5.36	Yes	No	1	9	6
153	R:R:F338	R:R:T384	2.59	Yes	No	1	9	6
154	R:R:F338	R:R:H387	10.18	Yes	No	1	9	9
155	R:R:P341	R:R:V340	3.53	Yes	No	0	9	8
156	R:R:F342	R:R:F379	3.22	No	No	0	3	9
157	R:R:F342	R:R:F380	7.5	No	No	0	3	6
158	R:R:I352	R:R:Y349	2.42	No	No	0	9	8
159	R:R:A372	R:R:Y349	5.34	No	No	0	7	8
160	R:R:R357	R:R:V353	10.46	No	No	0	5	5
161	R:R:F354	R:R:R357	4.28	No	No	0	3	5
162	R:R:F354	R:R:K358	12.41	No	No	0	3	5
163	R:R:K358	R:R:R355	3.71	No	No	0	5	7
164	R:R:F361	R:R:M356	16.17	No	No	0	5	7
165	R:R:R357	R:R:R365	3.2	No	No	0	5	7
166	R:R:N360	R:R:T359	7.31	No	No	0	6	3
167	R:R:F361	R:R:S364	3.96	No	No	0	5	7
168	R:R:F369	R:R:V373	7.87	No	No	0	4	3
169	R:R:L431	R:R:V371	4.47	No	No	0	7	8
170	R:R:V375	R:R:Y428	5.05	No	Yes	0	9	9
171	R:R:L427	R:R:V378	4.47	No	No	0	9	7
172	R:R:F379	R:R:W383	8.02	No	Yes	0	9	9
173	R:R:F380	R:R:T384	10.38	No	No	1	6	6
174	R:R:C382	R:R:W383	3.92	No	Yes	1	9	9
175	R:R:C382	R:R:N420	9.45	No	No	1	9	9
176	R:R:H387	R:R:W383	4.23	No	Yes	1	9	9
177	R:R:A417	R:R:W383	2.59	No	Yes	0	9	9
178	R:R:N420	R:R:W383	11.3	No	Yes	1	9	9
179	R:R:P385	R:R:T384	6.99	No	No	0	9	6
180	R:R:I414	R:R:Y386	4.84	No	No	0	5	8
181	R:R:V389	R:R:V406	4.81	No	Yes	0	4	7
182	R:R:D410	R:R:V389	5.84	No	No	0	9	4
183	R:R:L392	R:R:V406	7.45	No	Yes	0	9	7
184	R:R:L393	R:R:V406	5.96	No	Yes	0	1	7
185	R:R:I395	R:R:T396	4.56	No	No	0	5	3
186	R:R:E399	R:R:P398	6.29	No	No	0	3	3
187	R:R:L402	R:R:S400	3	No	No	0	3	7
188	R:R:G403	R:R:S400	3.71	No	No	0	3	7
189	R:R:L402	R:R:S401	4.5	No	No	0	3	4
190	R:R:H411	R:R:M407	3.94	No	No	0	4	1
191	R:R:S408	R:R:W409	3.71	No	No	0	6	5
192	R:R:D410	R:R:S413	4.42	No	No	0	9	6
193	R:R:I414	R:R:S413	3.1	No	No	0	5	6
194	R:R:N420	R:R:N424	12.26	No	No	0	9	9
195	R:R:C422	R:R:F423	2.79	No	No	0	8	6
196	R:R:F435	R:R:L430	7.31	Yes	No	0	9	7
197	R:R:K433	R:R:R436	6.19	No	No	0	7	8
198	R:R:D434	R:R:K437	2.77	No	No	0	8	6
199	R:R:K438	R:R:Q441	5.42	No	No	0	7	7
200	R:R:L104	R:R:W147	2.28	Yes	Yes	0	7	9
201	R:R:L122	R:R:W129	2.28	No	No	0	7	8
202	R:R:F77	R:R:H81	2.26	No	Yes	0	8	8
203	R:R:C34	R:R:G31	1.96	Yes	No	0	6	6
204	R:R:C72	R:R:G37	1.96	No	No	0	8	9
205	R:R:C422	R:R:G37	1.96	No	No	0	8	9
206	R:R:C143	R:R:G144	1.96	No	No	0	8	5
207	R:R:G403	R:R:V406	1.84	No	Yes	0	3	7
208	R:R:C34	R:R:C72	1.82	Yes	No	0	6	8
209	R:R:A108	R:R:A150	1.79	No	No	0	9	9
210	R:R:P323	R:R:V322	1.77	No	No	0	2	3
211	R:R:G37	R:R:L36	1.71	No	No	0	9	8
212	R:R:G40	R:R:L39	1.71	No	No	0	9	8
213	R:R:G40	R:R:L43	1.71	No	Yes	0	9	9
214	R:R:G91	R:R:L163	1.71	No	No	0	9	6
215	R:R:C382	R:R:V378	1.71	No	No	0	9	7
216	R:R:G432	R:R:L431	1.71	No	No	0	9	7
217	R:R:A429	R:R:V44	1.7	No	No	0	9	9
218	R:R:K126	R:R:P127	1.67	No	No	0	6	9
219	R:R:S442	R:R:V47	1.62	No	No	0	9	8
220	R:R:C71	R:R:M106	1.62	No	No	0	8	9
221	R:R:D397	R:R:P398	1.61	No	No	0	4	3
222	R:R:V136	R:R:V56	1.6	No	No	0	8	9
223	R:R:V136	R:R:V59	1.6	No	Yes	7	8	7
224	R:R:V148	R:R:V152	1.6	No	No	0	5	5
225	R:R:V155	R:R:V159	1.6	No	No	0	5	4
226	R:R:S364	R:R:T368	1.6	No	No	0	7	6
227	R:R:V371	R:R:V375	1.6	No	No	0	8	9
228	R:R:C34	R:R:L35	1.59	Yes	No	0	6	7
229	R:R:C34	R:R:L75	1.59	Yes	No	0	6	8
230	R:R:T54	R:R:V59	1.59	No	Yes	7	7	7
231	R:R:T54	R:R:V136	1.59	No	No	7	7	8
232	R:R:G86	R:R:H87	1.59	No	No	0	8	6
233	R:R:T368	R:R:V353	1.59	No	No	0	6	5
234	R:R:A439	R:R:L43	1.58	No	Yes	0	8	9
235	R:R:A374	R:R:L427	1.58	No	No	0	6	9
236	R:R:A415	R:R:L416	1.58	No	No	0	9	9
237	R:R:I102	R:R:S74	1.55	No	No	0	8	9
238	R:R:I102	R:R:S78	1.55	No	No	0	8	8
239	R:R:I165	R:R:S170	1.55	No	No	0	4	3
240	R:R:I29	R:R:V28	1.54	No	No	0	7	6
241	R:R:I347	R:R:V346	1.54	No	No	0	3	6
242	R:R:M412	R:R:S26	1.53	No	Yes	0	6	8
243	R:R:M407	R:R:S408	1.53	No	No	0	1	6
244	R:R:K367	R:R:V371	1.52	No	No	0	9	8
245	R:R:L30	R:R:S26	1.5	Yes	Yes	0	6	8
246	R:R:L82	R:R:S26	1.5	No	Yes	0	7	8
247	R:R:K358	R:R:T359	1.5	No	No	0	5	3
248	R:R:K363	R:R:T362	1.5	No	No	0	8	5
249	R:R:L43	R:R:V47	1.49	Yes	No	0	9	8
250	R:R:L339	R:R:V335	1.49	No	No	0	8	7
251	R:R:I83	R:R:M27	1.46	No	No	0	5	6
252	R:R:I331	R:R:M327	1.46	No	No	0	6	4
253	R:R:E404	R:R:S401	1.44	No	No	0	3	4
254	R:R:F426	R:R:P425	1.44	No	No	0	7	9
255	R:R:I443	R:R:L43	1.43	No	Yes	0	4	9
256	R:R:I329	R:R:L326	1.43	No	No	0	6	3
257	R:R:I128	R:R:N132	1.42	No	No	0	7	8
258	R:R:A429	R:R:F61	1.39	No	No	0	9	8
259	R:R:L45	R:R:L66	1.38	No	No	0	8	5
260	R:R:L388	R:R:L392	1.38	No	No	0	5	9
261	R:R:D162	R:R:L92	1.36	No	No	0	6	2
262	R:R:H125	R:R:K126	1.31	No	No	0	6	6
263	R:R:F342	R:R:V376	1.31	No	No	0	3	8
264	R:R:F343	R:R:V346	1.31	No	No	0	4	6
265	R:R:A115	R:R:W60	1.3	No	Yes	0	7	8
266	R:R:A405	R:R:W409	1.3	No	No	0	6	5
267	R:R:I443	R:R:R440	1.25	No	No	0	4	4
268	R:R:F164	R:R:M166	1.24	No	No	0	2	2
269	R:R:L430	R:R:R436	1.21	No	No	0	7	8
270	R:R:D434	R:R:F435	1.19	No	Yes	0	8	9
271	L:L:?1	R:R:G390	1.18	Yes	No	0	0	8
272	R:R:F61	R:R:Y428	1.03	No	Yes	0	8	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	10.848	5	0	0
2	R:R:F19	4.57	4	0	1
3	R:R:S26	1.8675	4	0	8
4	R:R:L30	3.2225	4	0	6
5	R:R:C34	1.74	4	0	6
6	R:R:L43	1.5525	4	0	9
7	R:R:V59	2.3375	4	7	7
8	R:R:W60	4.025	6	0	8
9	R:R:H63	7.2425	4	0	8
10	R:R:D68	5.962	5	5	9
11	R:R:F69	5.005	4	0	7
12	R:R:H81	4.1925	4	2	8
13	R:R:W88	6.22833	6	2	9
14	R:R:L104	4.0625	4	8	7
15	R:R:F107	3.7525	4	4	8
16	R:R:W147	4.0425	4	0	9
17	R:R:R333	5.4775	4	4	9
18	R:R:F338	5.1425	4	1	9
19	R:R:P341	3.655	4	0	9
20	R:R:W383	5.83429	7	1	9
21	R:R:V406	5.015	4	0	7
22	R:R:Y428	4.27	4	0	9
23	R:R:F435	4.4175	4	0	9

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y386	82.8435	14.51	Yes	No	0	0	8
2	R:R:M106	R:R:Y386	85.4666	2.39	No	No	0	9	8
3	R:R:M106	R:R:W383	89.3608	4.65	No	Yes	0	9	9
4	R:R:N420	R:R:W383	79.0007	11.3	No	Yes	1	9	9
5	R:R:N420	R:R:N424	82.3365	12.26	No	No	0	9	9
6	R:R:D68	R:R:N424	52.3659	5.39	Yes	No	0	9	9
7	R:R:D68	R:R:N41	70.8597	4.04	Yes	No	0	9	9
8	R:R:F69	R:R:N41	65.0625	4.83	Yes	No	0	7	9
9	R:R:F69	R:R:L38	59.133	2.44	Yes	No	0	7	7
10	R:R:C72	R:R:L38	57.1271	3.17	No	No	0	8	7
11	R:R:C34	R:R:C72	42.6745	1.82	Yes	No	0	6	8
12	R:R:C34	R:R:L75	36.2601	1.59	Yes	No	0	6	8
13	R:R:L30	R:R:L75	31.9104	5.54	Yes	No	0	6	8
14	R:R:L30	R:R:S26	18.5084	1.5	Yes	Yes	0	6	8
15	R:R:D23	R:R:S26	11.7855	2.94	No	Yes	0	4	8
16	R:R:C72	R:R:G37	14.0999	1.96	No	No	0	8	9
17	R:R:L113	R:R:N424	76.7744	6.87	No	No	0	9	9
18	R:R:L113	R:R:Y428	100	5.86	No	Yes	0	9	9
19	R:R:F61	R:R:Y428	42.9758	1.03	No	Yes	0	8	9
20	R:R:A429	R:R:F61	41.3372	1.39	No	No	0	9	8
21	R:R:A429	R:R:V44	39.6841	1.7	No	No	0	9	9
22	R:R:F435	R:R:V44	36.3262	5.24	Yes	No	0	9	9
23	R:R:F435	R:R:V47	26.0323	3.93	Yes	No	0	9	8
24	R:R:S442	R:R:V47	13.3578	1.62	No	No	0	9	8
25	R:R:K51	R:R:S442	11.6165	3.06	No	No	0	9	9
26	R:R:R120	R:R:Y428	75.2902	5.14	No	Yes	0	9	9
27	R:R:I116	R:R:R120	57.3475	3.76	No	No	0	9	9
28	R:R:I116	R:R:W60	56.0764	4.7	No	Yes	0	9	8
29	R:R:C143	R:R:W60	30.9552	5.22	No	Yes	0	8	8
30	R:R:C143	R:R:H63	27.5606	16.22	No	Yes	0	8	8
31	R:R:D119	R:R:W60	20.6245	4.47	No	Yes	0	9	8
32	R:R:H63	R:R:W147	22.6745	7.41	Yes	Yes	0	8	9
33	R:R:D68	R:R:L64	24.335	2.71	Yes	No	5	9	9
34	R:R:L113	R:R:L64	25.4298	4.15	No	No	0	9	9
35	R:R:L104	R:R:W147	15.2976	2.28	Yes	Yes	0	7	9
36	L:L:?1	R:R:S78	69.5224	4.13	Yes	No	0	0	8
37	R:R:H81	R:R:S78	69.4416	4.18	Yes	No	0	8	8
38	R:R:H81	R:R:W88	64.8714	6.35	Yes	Yes	2	8	9
39	R:R:P89	R:R:W88	10	5.4	No	Yes	2	8	9
40	R:R:C95	R:R:W88	53.5636	3.92	No	Yes	0	9	9
41	R:R:C95	R:R:L163	51.1683	4.76	No	No	0	9	6
42	R:R:L163	R:R:L92	48.7142	5.54	No	No	0	6	2
43	R:R:K96	R:R:L92	40.9993	4.23	No	No	0	9	2
44	R:R:K96	R:R:R161	36.6863	9.9	No	No	0	9	8
45	R:R:R161	R:R:V157	17.8839	6.54	No	No	0	8	8
46	R:R:R333	R:R:V157	16.363	2.62	Yes	No	0	9	8
47	R:R:V110	R:R:W383	25.4445	6.13	No	Yes	0	9	9
48	R:R:P341	R:R:V110	24.1734	3.53	Yes	No	0	9	9
49	R:R:P341	R:R:T114	21.2858	3.5	Yes	No	0	9	8
50	R:R:S117	R:R:T114	20.1396	3.2	No	No	0	9	8
51	R:R:C348	R:R:S117	19.4049	3.44	No	No	0	8	9
52	R:R:C121	R:R:C348	19.7281	7.28	No	No	0	8	8
53	R:R:C121	R:R:L351	26.9508	3.17	No	No	0	8	6
54	R:R:C121	R:R:I352	19.1624	3.27	No	No	0	8	9
55	R:R:R120	R:R:Y349	22.8068	7.2	No	No	0	9	8
56	R:R:I352	R:R:Y349	20.0294	2.42	No	No	0	9	8
57	R:R:D119	R:R:R134	19.0522	10.72	No	No	0	9	9
58	R:R:C130	R:R:R134	13.4166	2.79	No	No	0	8	9
59	R:R:C130	R:R:L122	11.543	3.17	No	No	0	8	7
60	R:R:H125	R:R:L351	25.3564	7.71	No	No	0	6	6
61	R:R:H125	R:R:R355	21.5944	4.51	No	No	0	6	7
62	R:R:R161	R:R:Y174	19.5004	5.14	No	No	0	8	8
63	R:R:L326	R:R:Y174	16.3703	5.86	No	No	0	3	8
64	R:R:L326	R:R:P323	13.3358	6.57	No	No	0	3	2
65	R:R:H387	R:R:W383	11.5577	4.23	No	Yes	1	9	9
66	R:R:K358	R:R:R355	20.6613	3.71	No	No	0	5	7
67	R:R:F354	R:R:K358	15.1506	12.41	No	No	0	3	5
68	R:R:F354	R:R:R357	13.2843	4.28	No	No	0	3	5
69	L:L:?1	R:R:D410	18.2145	15.86	Yes	No	0	0	9
70	R:R:D410	R:R:V389	16.4805	5.84	No	No	0	9	4
71	R:R:V389	R:R:V406	14.9375	4.81	No	Yes	0	4	7
72	R:R:L43	R:R:V47	11.4695	1.49	Yes	No	0	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:S78	4.13	0	Yes	No	0	8	0	1
L:L:?1	R:R:Y386	14.51	0	Yes	No	0	8	0	1
L:L:?1	R:R:D410	15.86	0	Yes	No	0	9	0	1
L:L:?1	R:R:H411	18.56	0	Yes	No	0	4	0	1
R:R:H81	R:R:S78	4.18	2	Yes	No	8	8	2	1
R:R:M106	R:R:Y386	2.39	0	No	No	9	8	2	1
R:R:I414	R:R:Y386	4.84	0	No	No	5	8	2	1
R:R:D410	R:R:V389	5.84	0	No	No	9	4	1	2
R:R:H411	R:R:M407	3.94	0	No	No	4	1	1	2
R:R:D410	R:R:S413	4.42	0	No	No	9	6	1	2
R:R:I414	R:R:S413	3.1	0	No	No	5	6	2	2
R:R:I102	R:R:S78	1.55	0	No	No	8	8	2	1
L:L:?1	R:R:G390	1.18	0	Yes	No	0	8	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9L0H_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	2.39
Number of Linked Nodes	263
Number of Links	272
Number of Hubs	23
Number of Links mediated by Hubs	95
Number of Communities	8
Number of Nodes involved in Communities	33
Number of Links involved in Communities	38

Path Summary
Number Of Nodes in MetaPath	73
Number Of Links MetaPath	72
Number of Shortest Paths	30135
Length Of Smallest Path	3
Average Path Length	15.3675
Length of Longest Path	37
Minimum Path Strength	1.21
Average Path Strength	5.17377
Maximum Path Strength	15.01
Minimum Path Correlation	0.7
Average Path Correlation	0.935088
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	3.7037
Average % Of Corr. Nodes	49.756
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	27.5392
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O09047
Sequence	>9L0H_nogp_Chain_R L F Q P Q D I A S M V I L G L T C L L G L L G N G L V L W V A G V K M K T T V N T V W F L H L T L A D F L C C L S L P F S L A H L I L Q G H W P Y G L F L C K L I P S I I I L N M F A S V F L L T A I S L D R C L I V H K P I W C Q N H R N V R T A F A I C G C V W V V A F V M C V P V F V Y R D L F I M D N R S I C R Y V P T P L M A I T I T R L V V G F L V P F F I M V I C Y S L I V F R M R K T N F T K S R N K T F R V A V A V V T V F F I C W T P Y H L V G V L L L I T D P E S S L G E A V M S W D H M S I A L A S A N S C F N P F L Y A L L G K D F R K K A R Q S I K G Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8HK2	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-	Gi1/β1/γ2	2.9	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK2 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-		2.9	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK3	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Gi1/β1/γ2	3.2	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK3 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.2	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8IA8	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	E7 peptide	-	Gi1/β1/γ2	2.86	2023-05-24	To be published
	8IA8 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	E7 peptide	-		2.86	2023-05-24	To be published
	8I95	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-	Go/β1/γ2	2.88	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I95 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-		2.88	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I97	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Go/β1/γ2	3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I97 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9A	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.57	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9A (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-		3.57	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9L	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-	Go/β1/γ2	3.18	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9L (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-		3.18	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9S	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Go/β1/γ2	3.26	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9S (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.26	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8J6D	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP141	-	Go/β1/γ2	3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8J6D (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP141	-		3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	9KVP	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	SB290157	-	Go/β1/γ2	2.79	2025-11-26	10.1101/2025.05.26.656101
	9KVP (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	SB290157	-		2.79	2025-11-26	10.1101/2025.05.26.656101
	9KZ2	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP67	-	Go/β1/γ2	3.43	2025-11-26	10.1101/2025.05.26.656101
	9KZ2 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP67	-		3.43	2025-11-26	10.1101/2025.05.26.656101
	9KZ8	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP67	-	Go/β1/γ2	3.3	2025-11-26	10.1101/2025.05.26.656101
	9KZ8 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP67	-		3.3	2025-11-26	10.1101/2025.05.26.656101
	9KZK	A	Peptide	Complement Peptide	C3a_B	Mus musculus	C3a (fragment)	-	Go/β1/γ2	3.54	2025-11-26	10.1101/2025.05.26.656101
	9KZK (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	C3a (fragment)	-		3.54	2025-11-26	10.1101/2025.05.26.656101
	9L0H	A	Peptide	Complement Peptide	C3a_B	Mus musculus	JR14a	-	Go/β1/γ2	3.57	2025-11-26	10.1101/2025.05.26.656101
	9L0H (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	JR14a	-		3.57	2025-11-26	10.1101/2025.05.26.656101
	9UMJ	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP54	-	Go/β1/γ2	3.38	2025-11-26	10.1101/2025.05.26.656101
	9UMJ (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP54	-		3.38	2025-11-26	10.1101/2025.05.26.656101
	9IPV	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	Gi1/β1/γ2	2.53	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	9IPV (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		2.53	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	9IPY	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	-	3.55	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	9ISI	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	-	3.56	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	8ZWF	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	-	3	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	8ZWF (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		3	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	8ZWG	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	Gi1/β1/γ2	2.87	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	8ZWG (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		2.87	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	9KUT	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	Go/β1/γ2	3.29	2025-11-26	10.1101/2025.05.26.656101
	9KUT (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		3.29	2025-11-26	10.1101/2025.05.26.656101
	9KV6	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-	Go/β1/γ2	2.88	2025-11-26	10.1101/2025.05.26.656101
	9KV6 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-		2.88	2025-11-26	10.1101/2025.05.26.656101
	9KV8	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-	Go/β1/γ2	3.17	2025-11-26	10.1101/2025.05.26.656101
	9KV8 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-		3.17	2025-11-26	10.1101/2025.05.26.656101

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9L0H_nogp.zip

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You can also read or download a guide explaining the meaning of all files and numerical data.