psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:D5	L:L:S2	5.89	No	No	0	0	0
2	L:L:F3	R:R:D23	8.36	No	No	1	0	4
3	L:L:F3	R:R:H411	5.66	No	Yes	1	0	4
4	L:L:K4	L:L:P7	8.36	Yes	No	1	0	0
5	L:L:K4	R:R:D410	4.15	Yes	Yes	1	0	9
6	L:L:M6	R:R:R161	3.72	No	Yes	0	0	8
7	L:L:P7	R:R:D410	6.44	No	Yes	1	0	9
8	L:L:?8	L:L:?9	21.14	Yes	Yes	0	0	0
9	L:L:?8	R:R:S78	6.63	Yes	No	0	0	8
10	L:L:?8	R:R:P99	5.8	Yes	No	0	0	8
11	L:L:?8	R:R:I102	7.56	Yes	No	0	0	8
12	L:L:?9	L:L:R10	4.94	Yes	Yes	1	0	0
13	L:L:?9	R:R:Y386	3.58	Yes	Yes	1	0	8
14	L:L:?9	R:R:I414	8.71	Yes	No	1	0	5
15	L:L:R10	R:R:R333	4.26	Yes	Yes	1	0	9
16	L:L:R10	R:R:Y386	11.32	Yes	Yes	1	0	8
17	L:L:R10	R:R:G390	6	Yes	No	0	0	8
18	L:L:R10	R:R:D410	9.53	Yes	Yes	1	0	9
19	R:R:F19	R:R:L18	12.18	No	No	0	1	1
20	R:R:F19	R:R:I24	3.77	No	No	0	1	7
21	R:R:P21	R:R:Q20	12.63	No	No	1	5	4
22	R:R:Q20	R:R:Q22	10.24	No	No	1	4	4
23	R:R:D23	R:R:Q20	9.14	No	No	1	4	4
24	R:R:P21	R:R:Q22	7.9	No	No	1	5	4
25	R:R:Q22	R:R:W409	7.67	No	Yes	0	4	5
26	R:R:D23	R:R:H411	10.08	No	Yes	1	4	4
27	R:R:A415	R:R:S26	3.42	No	No	0	9	8
28	R:R:L30	R:R:L75	5.54	No	Yes	0	6	8
29	R:R:A415	R:R:L30	4.73	No	No	0	9	6
30	R:R:L30	R:R:S418	4.5	No	No	0	6	9
31	R:R:G31	R:R:L79	3.42	No	No	0	6	6
32	R:R:C422	R:R:T33	6.76	No	No	0	8	9
33	R:R:C34	R:R:L75	7.94	No	Yes	3	6	8
34	R:R:C34	R:R:P76	3.77	No	No	3	6	9
35	R:R:F426	R:R:L36	7.31	No	No	0	7	8
36	R:R:F69	R:R:L38	3.65	Yes	No	0	7	7
37	R:R:C72	R:R:L38	3.17	No	No	0	8	7
38	R:R:N41	R:R:T65	5.85	Yes	No	0	9	9
39	R:R:D68	R:R:N41	4.04	Yes	Yes	0	9	9
40	R:R:F69	R:R:N41	6.04	Yes	Yes	0	7	9
41	R:R:C72	R:R:N41	3.15	No	Yes	0	8	9
42	R:R:N41	R:R:P425	6.52	Yes	No	0	9	9
43	R:R:T65	R:R:V44	6.35	No	No	0	9	9
44	R:R:A429	R:R:V44	5.09	No	No	0	9	9
45	R:R:V50	R:R:W46	8.58	No	No	0	6	8
46	R:R:F435	R:R:V47	3.93	Yes	No	4	9	8
47	R:R:K438	R:R:V47	13.66	Yes	No	4	7	8
48	R:R:K438	R:R:K51	11.49	Yes	No	0	7	9
49	R:R:D434	R:R:M52	5.54	No	No	0	8	9
50	R:R:K438	R:R:M52	23.04	Yes	No	0	7	9
51	R:R:T55	R:R:V56	3.17	No	No	0	9	9
52	R:R:T55	R:R:T58	6.28	No	No	0	9	9
53	R:R:R134	R:R:V56	6.54	Yes	No	0	9	9
54	R:R:N57	R:R:R134	4.82	No	Yes	0	8	9
55	R:R:V59	R:R:W60	4.9	No	Yes	0	7	8
56	R:R:H63	R:R:V59	4.15	Yes	No	6	8	7
57	R:R:F140	R:R:V59	7.87	No	No	6	3	7
58	R:R:I116	R:R:W60	4.7	No	Yes	0	9	8
59	R:R:D119	R:R:W60	15.63	No	Yes	0	9	8
60	R:R:A139	R:R:W60	5.19	No	Yes	0	8	8
61	R:R:I142	R:R:W60	3.52	No	Yes	0	5	8
62	R:R:F61	R:R:Y428	3.09	No	Yes	0	8	9
63	R:R:H63	R:R:L112	3.86	Yes	No	0	8	9
64	R:R:F140	R:R:H63	4.53	No	Yes	6	3	8
65	R:R:C143	R:R:H63	8.85	No	Yes	0	8	8
66	R:R:H63	R:R:W147	6.35	Yes	Yes	0	8	9
67	R:R:D68	R:R:L64	4.07	Yes	Yes	2	9	9
68	R:R:L113	R:R:L64	5.54	No	Yes	2	9	9
69	R:R:L64	R:R:N424	4.12	Yes	Yes	2	9	9
70	R:R:L64	R:R:Y428	4.69	Yes	Yes	2	9	9
71	R:R:L66	R:R:L70	4.15	No	No	0	5	5
72	R:R:D68	R:R:S109	4.42	Yes	No	0	9	9
73	R:R:D68	R:R:S421	5.89	Yes	No	0	9	9
74	R:R:D68	R:R:N424	12.12	Yes	Yes	2	9	9
75	R:R:L70	R:R:N105	4.12	No	No	0	5	9
76	R:R:C71	R:R:N105	4.72	No	No	0	8	9
77	R:R:C71	R:R:M106	3.24	No	No	0	8	9
78	R:R:C71	R:R:S421	6.89	No	No	0	8	9
79	R:R:I102	R:R:S74	4.64	No	No	0	8	9
80	R:R:L75	R:R:P76	3.28	Yes	No	3	8	9
81	R:R:L75	R:R:L79	4.15	Yes	No	3	8	6
82	R:R:L79	R:R:P76	3.28	No	No	3	6	9
83	R:R:F77	R:R:I98	10.05	No	No	0	8	8
84	R:R:H81	R:R:L82	6.43	No	No	0	8	7
85	R:R:G86	R:R:H81	7.94	No	No	0	8	8
86	R:R:H411	R:R:L82	6.43	Yes	No	0	4	7
87	R:R:L84	R:R:Q85	11.98	No	No	0	8	5
88	R:R:H87	R:R:Q85	8.65	No	No	0	6	5
89	R:R:W88	R:R:Y90	19.29	No	Yes	0	9	8
90	R:R:C95	R:R:W88	3.92	No	No	7	9	9
91	R:R:C172	R:R:W88	7.84	No	No	7	9	9
92	R:R:D162	R:R:L92	6.79	No	No	0	6	2
93	R:R:C172	R:R:C95	5.46	No	No	7	9	9
94	R:R:F158	R:R:K96	23.58	No	No	0	8	9
95	R:R:I98	R:R:P99	3.39	No	No	0	8	8
96	R:R:P99	R:R:R161	7.21	No	Yes	0	8	8
97	R:R:S100	R:R:V157	6.46	No	No	0	8	8
98	R:R:F158	R:R:S100	6.61	No	No	0	8	8
99	R:R:F107	R:R:I103	5.02	Yes	Yes	1	8	5
100	R:R:C154	R:R:I103	3.27	No	Yes	0	7	5
101	R:R:I103	R:R:V157	4.61	Yes	No	0	5	8
102	R:R:I103	R:R:R333	3.76	Yes	Yes	1	5	9
103	R:R:F151	R:R:L104	3.65	No	No	0	6	7
104	R:R:C154	R:R:L104	3.17	No	No	0	7	7
105	R:R:M106	R:R:W383	4.65	No	Yes	0	9	9
106	R:R:F107	R:R:M153	9.95	Yes	No	1	8	8
107	R:R:F107	R:R:R333	7.48	Yes	Yes	1	8	9
108	R:R:A108	R:R:W147	6.48	No	Yes	0	9	9
109	R:R:F111	R:R:V110	3.93	Yes	No	0	8	9
110	R:R:L113	R:R:N424	9.61	No	Yes	2	9	9
111	R:R:L113	R:R:Y428	9.38	No	Yes	2	9	9
112	R:R:P341	R:R:T114	3.5	No	No	0	9	8
113	R:R:I344	R:R:T114	4.56	No	No	0	6	8
114	R:R:I116	R:R:R120	5.01	No	No	2	9	9
115	R:R:I116	R:R:Y428	6.04	No	Yes	2	9	9
116	R:R:M345	R:R:S117	7.67	No	No	2	7	9
117	R:R:C348	R:R:S117	5.16	No	No	0	8	9
118	R:R:S117	R:R:Y349	8.9	No	Yes	2	9	8
119	R:R:I344	R:R:L118	4.28	No	No	0	6	8
120	R:R:C348	R:R:L118	3.17	No	No	0	8	8
121	R:R:D119	R:R:I123	8.4	No	No	5	9	5
122	R:R:D119	R:R:R134	11.91	No	Yes	5	9	9
123	R:R:R120	R:R:Y349	8.23	No	Yes	2	9	8
124	R:R:R120	R:R:Y428	3.09	No	Yes	2	9	9
125	R:R:C121	R:R:H125	7.37	No	No	0	8	6
126	R:R:C121	R:R:C348	5.46	No	No	0	8	8
127	R:R:C121	R:R:I352	3.27	No	No	0	8	9
128	R:R:C130	R:R:L122	4.76	No	No	0	8	7
129	R:R:I123	R:R:R134	10.02	No	Yes	5	5	9
130	R:R:I352	R:R:V124	9.22	No	No	0	9	9
131	R:R:H125	R:R:R355	4.51	No	No	0	6	7
132	R:R:H133	R:R:W129	15.87	No	No	0	8	8
133	R:R:C130	R:R:R134	5.57	No	Yes	0	8	9
134	R:R:H133	R:R:N132	7.65	No	No	0	8	8
135	R:R:N135	R:R:T138	5.85	No	No	0	5	6
136	R:R:M153	R:R:R333	3.72	No	Yes	1	8	9
137	R:R:M153	R:R:V336	4.56	No	No	0	8	4
138	R:R:P156	R:R:V155	3.53	No	No	0	9	5
139	R:R:I329	R:R:P156	3.39	No	No	0	6	9
140	R:R:R161	R:R:V157	3.92	Yes	No	0	8	8
141	R:R:V159	R:R:Y160	5.05	No	No	0	4	8
142	R:R:Y160	R:R:Y174	9.93	No	Yes	0	8	8
143	R:R:R161	R:R:Y174	15.43	Yes	Yes	0	8	8
144	R:R:D162	R:R:N175	5.39	No	No	0	6	5
145	R:R:L163	R:R:M166	9.9	No	No	0	6	2
146	R:R:F164	R:R:I165	3.77	Yes	No	8	2	4
147	R:R:F164	R:R:R173	10.69	Yes	No	8	2	1
148	R:R:F164	R:R:N175	6.04	Yes	No	0	2	5
149	R:R:D167	R:R:I165	5.6	No	No	0	3	4
150	R:R:I165	R:R:R173	5.01	No	No	8	4	1
151	R:R:F176	R:R:R173	5.34	Yes	No	0	5	1
152	R:R:F176	R:R:Y174	6.19	Yes	Yes	0	5	8
153	R:R:I329	R:R:Y174	3.63	No	Yes	0	6	8
154	R:R:F176	R:R:P323	10.11	Yes	No	0	5	2
155	R:R:F176	R:R:L326	10.96	Yes	No	0	5	3
156	R:R:P323	R:R:V322	3.53	No	No	0	2	3
157	R:R:L326	R:R:V322	4.47	No	No	0	3	3
158	R:R:P325	R:R:T324	5.25	No	No	0	4	5
159	R:R:I329	R:R:R333	3.76	No	Yes	0	6	9
160	R:R:R333	R:R:Y386	4.12	Yes	Yes	1	9	8
161	R:R:H387	R:R:L334	5.14	No	No	0	9	7
162	R:R:G337	R:R:P341	4.06	No	No	0	9	9
163	R:R:F338	R:R:T384	7.78	No	No	0	9	6
164	R:R:F338	R:R:H387	10.18	No	No	0	9	9
165	R:R:P341	R:R:V340	3.53	No	No	0	9	8
166	R:R:F342	R:R:V346	5.24	Yes	No	0	3	6
167	R:R:F342	R:R:F379	9.65	Yes	Yes	0	3	9
168	R:R:F342	R:R:F380	9.65	Yes	No	0	3	6
169	R:R:M345	R:R:Y349	3.59	No	Yes	2	7	8
170	R:R:F379	R:R:M345	6.22	Yes	No	0	9	7
171	R:R:V346	R:R:V376	3.21	No	No	0	6	8
172	R:R:A372	R:R:Y349	5.34	No	Yes	0	7	8
173	R:R:V375	R:R:Y349	3.79	No	Yes	0	9	8
174	R:R:K358	R:R:R355	8.66	No	No	0	5	7
175	R:R:F361	R:R:M356	17.42	No	No	0	5	7
176	R:R:M356	R:R:T368	9.03	No	No	0	7	6
177	R:R:R357	R:R:R365	11.73	No	No	0	5	7
178	R:R:F361	R:R:N360	4.83	No	No	0	5	6
179	R:R:S364	R:R:T368	4.8	No	No	0	7	6
180	R:R:F369	R:R:V373	7.87	No	No	0	4	3
181	R:R:L431	R:R:V371	4.47	No	No	0	7	8
182	R:R:V375	R:R:Y428	7.57	No	Yes	0	9	9
183	R:R:L427	R:R:V378	4.47	No	No	0	9	7
184	R:R:F379	R:R:W383	11.02	Yes	Yes	0	9	9
185	R:R:F380	R:R:T384	14.27	No	No	0	6	6
186	R:R:C382	R:R:N420	7.87	No	No	0	9	9
187	R:R:W383	R:R:Y386	5.79	Yes	Yes	1	9	8
188	R:R:A417	R:R:W383	3.89	No	Yes	1	9	9
189	R:R:N420	R:R:W383	12.43	No	Yes	0	9	9
190	R:R:P385	R:R:T384	3.5	No	No	0	9	6
191	R:R:P385	R:R:S413	3.56	No	No	0	9	6
192	R:R:H387	R:R:Y386	3.27	No	Yes	0	9	8
193	R:R:I414	R:R:Y386	6.04	No	Yes	1	5	8
194	R:R:A417	R:R:Y386	4	No	Yes	1	9	8
195	R:R:L388	R:R:L392	4.15	No	No	0	5	9
196	R:R:D410	R:R:V389	5.84	Yes	No	0	9	4
197	R:R:S413	R:R:V389	6.46	No	No	0	6	4
198	R:R:I395	R:R:T396	9.12	No	No	0	5	3
199	R:R:D397	R:R:P398	6.44	No	No	0	4	3
200	R:R:D397	R:R:E399	3.9	No	No	0	4	3
201	R:R:M407	R:R:P398	3.35	No	No	0	1	3
202	R:R:S408	R:R:W409	7.41	No	Yes	0	6	5
203	R:R:M412	R:R:W409	4.65	No	Yes	0	6	5
204	R:R:L416	R:R:M412	5.65	No	No	0	9	6
205	R:R:N420	R:R:N424	12.26	No	Yes	0	9	9
206	R:R:F435	R:R:L430	3.65	Yes	No	0	9	7
207	R:R:L430	R:R:R436	4.86	No	No	0	7	8
208	R:R:F435	R:R:K438	4.96	Yes	Yes	4	9	7
209	R:R:I331	R:R:T330	3.04	No	No	0	6	8
210	R:R:F69	R:R:G42	3.01	Yes	No	0	7	6
211	R:R:L32	R:R:V28	2.98	No	No	0	6	6
212	R:R:L394	R:R:V322	2.98	No	No	0	7	3
213	R:R:L334	R:R:V391	2.98	No	No	0	7	7
214	R:R:L392	R:R:V406	2.98	No	No	0	9	7
215	R:R:L45	R:R:T65	2.95	No	No	0	8	9
216	R:R:L62	R:R:T54	2.95	No	No	0	8	7
217	R:R:I352	R:R:M356	2.92	No	No	0	9	7
218	L:L:K4	R:R:M407	2.88	Yes	No	0	0	1
219	R:R:I101	R:R:L97	2.85	No	No	0	6	6
220	R:R:I347	R:R:L351	2.85	No	No	0	3	6
221	R:R:K126	R:R:L122	2.82	No	No	0	6	7
222	R:R:H411	R:R:S26	2.79	Yes	No	0	4	8
223	R:R:C382	R:R:F423	2.79	No	No	0	9	6
224	R:R:P89	R:R:Y90	2.78	No	Yes	0	8	8
225	R:R:A48	R:R:F435	2.77	No	Yes	0	6	9
226	R:R:A150	R:R:F111	2.77	No	Yes	0	9	8
227	R:R:L334	R:R:L339	2.77	No	No	0	7	8
228	R:R:A419	R:R:F423	2.77	No	No	0	8	6
229	R:R:A429	R:R:F435	2.77	No	Yes	0	9	9
230	L:L:K4	R:R:H411	2.62	Yes	Yes	1	0	4
231	R:R:F107	R:R:V110	2.62	Yes	No	0	8	9
232	R:R:F379	R:R:V110	2.62	Yes	No	0	9	9
233	R:R:F111	R:R:V336	2.62	Yes	No	0	8	4
234	R:R:F140	R:R:V136	2.62	No	No	0	3	8
235	R:R:F423	R:R:V378	2.62	No	No	0	6	7
236	R:R:A115	R:R:W60	2.59	No	Yes	0	7	8
237	R:R:A67	R:R:W147	2.59	No	Yes	0	9	9
238	R:R:H125	R:R:L351	2.57	No	No	0	6	6
239	L:L:S2	L:L:Y1	2.54	No	No	0	0	0
240	L:L:D5	R:R:H81	2.52	No	No	0	0	8
241	R:R:S442	R:R:W46	2.47	No	No	0	9	8
242	L:L:R10	R:R:L393	2.43	Yes	No	0	0	1
243	R:R:N366	R:R:R365	2.41	No	No	0	5	7
244	R:R:K126	R:R:W129	2.32	No	No	0	6	8
245	R:R:F342	R:R:F343	2.14	Yes	No	0	3	4
246	R:R:C72	R:R:G37	1.96	No	No	0	8	9
247	R:R:C422	R:R:G37	1.96	No	No	0	8	9
248	R:R:P323	R:R:P325	1.95	No	No	0	2	4
249	R:R:G403	R:R:V406	1.84	No	No	0	3	7
250	R:R:G37	R:R:L36	1.71	No	No	0	9	8
251	R:R:G40	R:R:L39	1.71	No	No	0	9	8
252	R:R:G403	R:R:L402	1.71	No	No	0	3	3
253	R:R:I128	R:R:P127	1.69	No	No	0	7	9
254	R:R:K126	R:R:P127	1.67	No	No	0	6	9
255	R:R:C145	R:R:I142	1.64	No	No	0	6	5
256	R:R:C382	R:R:I381	1.64	No	No	0	9	6
257	R:R:A415	R:R:I29	1.62	No	No	0	9	7
258	R:R:S442	R:R:V47	1.62	No	No	0	9	8
259	R:R:S350	R:R:V346	1.62	No	No	0	6	6
260	R:R:V148	R:R:V152	1.6	No	No	0	5	5
261	R:R:V335	R:R:V340	1.6	No	No	0	7	8
262	R:R:V371	R:R:V375	1.6	No	No	0	8	9
263	R:R:V389	R:R:V406	1.6	No	No	0	4	7
264	R:R:C172	R:R:L163	1.59	No	No	0	9	6
265	R:R:T332	R:R:V336	1.59	No	No	0	7	4
266	R:R:T377	R:R:V378	1.59	No	No	0	5	7
267	R:R:A48	R:R:L62	1.58	No	No	0	6	8
268	R:R:A439	R:R:L430	1.58	No	No	0	8	7
269	R:R:T359	R:R:T362	1.57	No	No	0	3	5
270	R:R:I101	R:R:S74	1.55	No	No	0	6	9
271	R:R:I331	R:R:V335	1.54	No	No	0	6	7
272	R:R:K363	R:R:T362	1.5	No	No	0	8	5
273	R:R:L112	R:R:V146	1.49	No	No	0	9	8
274	R:R:I331	R:R:M327	1.46	No	No	0	6	4
275	R:R:N360	R:R:T359	1.46	No	No	0	6	3
276	R:R:G91	R:R:Y90	1.45	No	Yes	0	9	8
277	R:R:I98	R:R:L94	1.43	No	No	0	8	8
278	R:R:G144	R:R:W147	1.41	No	Yes	0	5	9
279	L:L:D5	R:R:I171	1.4	No	No	0	0	1
280	R:R:D167	R:R:I171	1.4	No	No	0	3	1
281	R:R:L18	R:R:L84	1.38	No	No	0	1	8
282	R:R:L163	R:R:L92	1.38	No	No	0	6	2
283	R:R:A80	R:R:Y90	1.33	No	Yes	0	5	8
284	R:R:F111	R:R:V149	1.31	Yes	No	0	8	4
285	R:R:F369	R:R:V353	1.31	No	No	0	4	5
286	R:R:A405	R:R:W409	1.3	No	Yes	0	6	5
287	R:R:I443	R:R:R440	1.25	No	No	0	4	4
288	R:R:F69	R:R:L73	1.22	Yes	No	0	7	8
289	R:R:N135	R:R:R137	1.21	No	No	0	5	6
290	R:R:D177	R:R:F164	1.19	No	Yes	0	2	2
291	R:R:Q441	R:R:R440	1.17	No	No	0	7	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:K4	4.5025	4	1	0
2	L:L:?8	10.2825	4	0	0
3	L:L:?9	9.5925	4	1	0
4	L:L:R10	6.41333	6	1	0
5	R:R:N41	5.12	5	0	9
6	R:R:W60	6.08833	6	0	8
7	R:R:H63	5.548	5	6	8
8	R:R:L64	4.605	4	2	9
9	R:R:D68	6.108	5	2	9
10	R:R:F69	3.48	4	0	7
11	R:R:L75	5.2275	4	3	8
12	R:R:Y90	6.2125	4	0	8
13	R:R:I103	4.165	4	1	5
14	R:R:F107	6.2675	4	1	8
15	R:R:F111	2.6575	4	0	8
16	R:R:R134	7.772	5	5	9
17	R:R:W147	4.2075	4	0	9
18	R:R:R161	7.57	4	0	8
19	R:R:F164	5.4225	4	8	2
20	R:R:Y174	8.795	4	0	8
21	R:R:F176	8.15	4	0	5
22	R:R:R333	4.51667	6	1	9
23	R:R:F342	6.67	4	0	3
24	R:R:Y349	5.97	5	2	8
25	R:R:F379	7.3775	4	0	9
26	R:R:W383	7.556	5	1	9
27	R:R:Y386	5.44571	7	1	8
28	R:R:W409	5.2575	4	0	5
29	R:R:D410	6.49	4	1	9
30	R:R:H411	5.516	5	1	4
31	R:R:N424	9.5275	4	2	9
32	R:R:Y428	5.64333	6	2	9
33	R:R:F435	3.616	5	4	9
34	R:R:K438	13.2875	4	4	7

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	R:R:H81	R:R:L82	10.6023	6.43	No	No	0	8	7
2	R:R:H411	R:R:L82	11.7343	6.43	Yes	No	0	4	7
3	R:R:D23	R:R:H411	14.2389	10.08	No	Yes	1	4	4
4	L:L:K4	R:R:H411	38.6243	2.62	Yes	Yes	1	0	4
5	L:L:K4	R:R:D410	44.4581	4.15	Yes	Yes	1	0	9
6	R:R:F176	R:R:R173	32.4165	5.34	Yes	No	0	5	1
7	R:R:F176	R:R:Y174	47.4851	6.19	Yes	Yes	0	5	8
8	L:L:?8	L:L:?9	15.2377	21.14	Yes	Yes	0	0	0
9	L:L:R10	R:R:D410	54.1744	9.53	Yes	Yes	1	0	9
10	L:L:R10	R:R:Y386	44.8986	11.32	Yes	Yes	1	0	8
11	L:L:R10	R:R:R333	10.4999	4.26	Yes	Yes	1	0	9
12	R:R:D23	R:R:Q20	12.7382	9.14	No	No	1	4	4
13	R:R:H411	R:R:S26	15.8216	2.79	Yes	No	0	4	8
14	R:R:A415	R:R:S26	14.285	3.42	No	No	0	9	8
15	R:R:A415	R:R:L30	11.1811	4.73	No	No	0	9	6
16	R:R:W383	R:R:Y386	100	5.79	Yes	Yes	1	9	8
17	R:R:N420	R:R:W383	67.1481	12.43	No	Yes	0	9	9
18	R:R:N420	R:R:N424	64.8125	12.26	No	Yes	0	9	9
19	R:R:D68	R:R:N424	25.3278	12.12	Yes	Yes	2	9	9
20	R:R:D68	R:R:N41	41.6615	4.04	Yes	Yes	0	9	9
21	R:R:C72	R:R:N41	10.0133	3.15	No	Yes	0	8	9
22	R:R:N41	R:R:T65	25.8861	5.85	Yes	No	0	9	9
23	R:R:T65	R:R:V44	23.2842	6.35	No	No	0	9	9
24	R:R:A429	R:R:V44	21.9832	5.09	No	No	0	9	9
25	R:R:A429	R:R:F435	20.6464	2.77	No	Yes	0	9	9
26	R:R:F379	R:R:W383	43.362	11.02	Yes	Yes	0	9	9
27	R:R:F379	R:R:M345	57.4933	6.22	Yes	No	0	9	7
28	R:R:M345	R:R:Y349	32.0733	3.59	No	Yes	2	7	8
29	R:R:R120	R:R:Y349	38.7574	8.23	No	Yes	2	9	8
30	R:R:I116	R:R:R120	31.3512	5.01	No	No	2	9	9
31	R:R:I116	R:R:W60	71.7937	4.7	No	Yes	0	9	8
32	R:R:D119	R:R:W60	35.9148	15.63	No	Yes	0	9	8
33	R:R:D119	R:R:R134	31.2897	11.91	No	Yes	5	9	9
34	R:R:L64	R:R:N424	20.001	4.12	Yes	Yes	2	9	9
35	R:R:L64	R:R:Y428	38.4808	4.69	Yes	Yes	2	9	9
36	R:R:I116	R:R:Y428	42.6142	6.04	No	Yes	2	9	9
37	R:R:L113	R:R:N424	20.2008	9.61	No	Yes	2	9	9
38	R:R:L113	R:R:Y428	19.7398	9.38	No	Yes	2	9	9
39	R:R:V59	R:R:W60	26.9258	4.9	No	Yes	0	7	8
40	R:R:H63	R:R:V59	19.622	4.15	Yes	No	6	8	7
41	R:R:F164	R:R:N175	23.6837	6.04	Yes	No	0	2	5
42	R:R:D162	R:R:N175	21.7476	5.39	No	No	0	6	5
43	R:R:D162	R:R:L92	19.8013	6.79	No	No	0	6	2
44	R:R:L163	R:R:L92	17.8447	1.38	No	No	0	6	2
45	R:R:C172	R:R:L163	13.9008	1.59	No	No	0	9	6
46	R:R:F107	R:R:R333	15.3452	7.48	Yes	Yes	1	8	9
47	R:R:F107	R:R:V110	19.8986	2.62	Yes	No	0	8	9
48	R:R:M345	R:R:S117	25.1434	7.67	No	No	2	7	9
49	R:R:C348	R:R:S117	40.8523	5.16	No	No	0	8	9
50	R:R:C348	R:R:L118	16.1289	3.17	No	No	0	8	8
51	R:R:I344	R:R:L118	14.5616	4.28	No	No	0	6	8
52	R:R:I344	R:R:T114	12.984	4.56	No	No	0	6	8
53	R:R:P341	R:R:T114	11.3962	3.5	No	No	0	9	8
54	R:R:C121	R:R:C348	24.9641	5.46	No	No	0	8	8
55	R:R:C121	R:R:I352	15.9445	3.27	No	No	0	8	9
56	R:R:C130	R:R:R134	19.704	5.57	No	Yes	0	8	9
57	R:R:C130	R:R:L122	17.2762	4.76	No	No	0	8	7
58	R:R:K126	R:R:L122	14.8381	2.82	No	No	0	6	7
59	R:R:I329	R:R:Y174	50.4558	3.63	No	Yes	0	6	8
60	R:R:D410	R:R:V389	10.9353	5.84	Yes	No	0	9	4
61	R:R:F342	R:R:F379	10.0594	9.65	Yes	Yes	0	3	9
62	R:R:I352	R:R:M356	12.7945	2.92	No	No	0	9	7
63	R:R:C382	R:R:N420	10.2489	7.87	No	No	0	9	9
64	R:R:I329	R:R:R333	55.0502	3.76	No	Yes	0	6	9
65	R:R:F164	R:R:R173	25.0102	10.69	Yes	No	8	2	1
66	R:R:R333	R:R:Y386	41.5745	4.12	Yes	Yes	1	9	8
67	L:L:?9	R:R:Y386	13.066	3.58	Yes	Yes	1	0	8
68	R:R:F379	R:R:V110	21.9627	2.62	Yes	No	0	9	9
69	R:R:D68	R:R:L64	19.161	4.07	Yes	Yes	2	9	9
70	R:R:S117	R:R:Y349	17.0867	8.9	No	Yes	2	9	8

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:F3	R:R:D23	8.36	1	No	No	0	4	0	1
L:L:F3	R:R:H411	5.66	1	No	Yes	0	4	0	1
L:L:K4	R:R:D410	4.15	1	Yes	Yes	0	9	0	1
L:L:M6	R:R:R161	3.72	0	No	Yes	0	8	0	1
L:L:P7	R:R:D410	6.44	1	No	Yes	0	9	0	1
L:L:?8	R:R:S78	6.63	0	Yes	No	0	8	0	1
L:L:?8	R:R:P99	5.8	0	Yes	No	0	8	0	1
L:L:?8	R:R:I102	7.56	0	Yes	No	0	8	0	1
L:L:?9	R:R:Y386	3.58	1	Yes	Yes	0	8	0	1
L:L:?9	R:R:I414	8.71	1	Yes	No	0	5	0	1
L:L:R10	R:R:R333	4.26	1	Yes	Yes	0	9	0	1
L:L:R10	R:R:Y386	11.32	1	Yes	Yes	0	8	0	1
L:L:R10	R:R:G390	6	1	Yes	No	0	8	0	1
L:L:R10	R:R:D410	9.53	1	Yes	Yes	0	9	0	1
R:R:D23	R:R:Q20	9.14	1	No	No	4	4	1	2
R:R:D23	R:R:H411	10.08	1	No	Yes	4	4	1	1
R:R:I102	R:R:S74	4.64	0	No	No	8	9	1	2
R:R:H81	R:R:L82	6.43	0	No	No	8	7	1	2
R:R:G86	R:R:H81	7.94	0	No	No	8	8	2	1
R:R:H411	R:R:L82	6.43	1	Yes	No	4	7	1	2
R:R:I98	R:R:P99	3.39	0	No	No	8	8	2	1
R:R:P99	R:R:R161	7.21	0	No	Yes	8	8	1	1
R:R:F107	R:R:I103	5.02	1	Yes	Yes	8	5	2	2
R:R:I103	R:R:V157	4.61	1	Yes	No	5	8	2	2
R:R:I103	R:R:R333	3.76	1	Yes	Yes	5	9	2	1
R:R:F107	R:R:M153	9.95	1	Yes	No	8	8	2	2
R:R:F107	R:R:R333	7.48	1	Yes	Yes	8	9	2	1
R:R:M153	R:R:R333	3.72	1	No	Yes	8	9	2	1
R:R:R161	R:R:V157	3.92	0	Yes	No	8	8	1	2
R:R:R161	R:R:Y174	15.43	0	Yes	Yes	8	8	1	2
R:R:I329	R:R:Y174	3.63	0	No	Yes	6	8	2	2
R:R:I329	R:R:R333	3.76	0	No	Yes	6	9	2	1
R:R:R333	R:R:Y386	4.12	1	Yes	Yes	9	8	1	1
R:R:W383	R:R:Y386	5.79	1	Yes	Yes	9	8	2	1
R:R:A417	R:R:W383	3.89	1	No	Yes	9	9	2	2
R:R:H387	R:R:Y386	3.27	0	No	Yes	9	8	2	1
R:R:I414	R:R:Y386	6.04	1	No	Yes	5	8	1	1
R:R:A417	R:R:Y386	4	1	No	Yes	9	8	2	1
R:R:D410	R:R:V389	5.84	1	Yes	No	9	4	1	2
R:R:M407	R:R:P398	3.35	0	No	No	1	3	1	2
L:L:K4	R:R:M407	2.88	1	Yes	No	0	1	0	1
R:R:H411	R:R:S26	2.79	1	Yes	No	4	8	1	2
L:L:K4	R:R:H411	2.62	1	Yes	Yes	0	4	0	1
L:L:D5	R:R:H81	2.52	0	No	No	0	8	0	1
L:L:R10	R:R:L393	2.43	1	Yes	No	0	1	0	1
L:L:D5	R:R:I171	1.4	0	No	No	0	1	0	1
R:R:D167	R:R:I171	1.4	0	No	No	3	1	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9KZ8_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.09
Number of Linked Nodes	268
Number of Links	291
Number of Hubs	34
Number of Links mediated by Hubs	130
Number of Communities	8
Number of Nodes involved in Communities	48
Number of Links involved in Communities	61

Path Summary
Number Of Nodes in MetaPath	71
Number Of Links MetaPath	70
Number of Shortest Paths	41899
Length Of Smallest Path	3
Average Path Length	13.1807
Length of Longest Path	30
Minimum Path Strength	1.21
Average Path Strength	6.18811
Maximum Path Strength	18.35
Minimum Path Correlation	0.7
Average Path Correlation	0.918936
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	4.16667
Average % Of Corr. Nodes	45.6899
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	45.0469
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function
Gene Ontology	Biological Process
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	MLE
PDB Residues	L:L:?8
Environment Details	Open EMBL-EBI Page
Code	MLE
Name	N-METHYLLEUCINE
Synonyms
Identifier
Formula	C7 H15 N O2
Molecular Weight	145.199
SMILES
PubChem	2777993
Formal Charge	0
Total Atoms	25
Total Chiral Atoms	1
Total Bonds	24
Total Aromatic Bonds	0


Code	DAL
PDB Residues	L:L:?9
Environment Details	Open EMBL-EBI Page
Code	DAL
Name	D-Alanine
Synonyms	D-Alanine
Identifier
Formula	C3 H7 N O2
Molecular Weight	89.093
SMILES
PubChem	71080
Formal Charge	0
Total Atoms	13
Total Chiral Atoms	1
Total Bonds	12
Total Aromatic Bonds	0


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	O09047
Sequence	>9KZ8_nogp_Chain_R P L F Q P Q D I A S M V I L G L T C L L G L L G N G L V L W V A G V K M K T T V N T V W F L H L T L A D F L C C L S L P F S L A H L I L Q G H W P Y G L F L C K L I P S I I I L N M F A S V F L L T A I S L D R C L I V H K P I W C Q N H R N V R T A F A I C G C V W V V A F V M C V P V F V Y R D L F I M D I C R Y N F D V P T P L M A I T I T R L V V G F L V P F F I M V I C Y S L I V F R M R K T N F T K S R N K T F R V A V A V V T V F F I C W T P Y H L V G V L L L I T D P E S S L G E A V M S W D H M S I A L A S A N S C F N P F L Y A L L G K D F R K K A R Q S I Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	8HK2	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-	Gi1/β1/γ2	2.9	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK2 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-		2.9	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK3	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Gi1/β1/γ2	3.2	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8HK3 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.2	2023-05-10	doi.org/10.1038/s41589-023-01339-w
	8IA8	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	E7 peptide	-	Gi1/β1/γ2	2.86	2023-05-24	To be published
	8IA8 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	E7 peptide	-		2.86	2023-05-24	To be published
	8I95	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-	Go/β1/γ2	2.88	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I95 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-		2.88	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I97	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Go/β1/γ2	3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I97 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9A	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-	chim(NtGi1-Gs-CtGq)/β1/γ2	3.57	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9A (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP54	-		3.57	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9L	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-	Go/β1/γ2	3.18	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9L (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	C3a	-		3.18	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9S	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	Go/β1/γ2	3.26	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8I9S (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-		3.26	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8J6D	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP141	-	Go/β1/γ2	3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	8J6D (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP141	-		3.1	2023-10-18	doi.org/10.1016/j.cell.2023.09.020
	9KVP	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	SB290157	-	Go/β1/γ2	2.79	2025-11-26	10.1101/2025.05.26.656101
	9KVP (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	SB290157	-		2.79	2025-11-26	10.1101/2025.05.26.656101
	9KZ2	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP67	-	Go/β1/γ2	3.43	2025-11-26	10.1101/2025.05.26.656101
	9KZ2 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	EP67	-		3.43	2025-11-26	10.1101/2025.05.26.656101
	9KZ8	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP67	-	Go/β1/γ2	3.3	2025-11-26	10.1101/2025.05.26.656101
	9KZ8 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP67	-		3.3	2025-11-26	10.1101/2025.05.26.656101
	9KZK	A	Peptide	Complement Peptide	C3a_B	Mus musculus	C3a (fragment)	-	Go/β1/γ2	3.54	2025-11-26	10.1101/2025.05.26.656101
	9KZK (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	C3a (fragment)	-		3.54	2025-11-26	10.1101/2025.05.26.656101
	9L0H	A	Peptide	Complement Peptide	C3a_B	Mus musculus	JR14a	-	Go/β1/γ2	3.57	2025-11-26	10.1101/2025.05.26.656101
	9L0H (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	JR14a	-		3.57	2025-11-26	10.1101/2025.05.26.656101
	9UMJ	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP54	-	Go/β1/γ2	3.38	2025-11-26	10.1101/2025.05.26.656101
	9UMJ (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	EP54	-		3.38	2025-11-26	10.1101/2025.05.26.656101
	9IPV	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	Gi1/β1/γ2	2.53	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	9IPV (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		2.53	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	9IPY	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	-	3.55	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	9ISI	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	-	-	-	3.56	2025-04-23	doi.org/10.1038/s44318-025-00429-w
	8ZWF	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	-	3	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	8ZWF (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		3	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	8ZWG	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	Gi1/β1/γ2	2.87	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	8ZWG (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		2.87	2025-05-14	doi.org/10.1038/s41421-024-00765-x
	9KUT	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-	Go/β1/γ2	3.29	2025-11-26	10.1101/2025.05.26.656101
	9KUT (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Homo sapiens	JR14a	-		3.29	2025-11-26	10.1101/2025.05.26.656101
	9KV6	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-	Go/β1/γ2	2.88	2025-11-26	10.1101/2025.05.26.656101
	9KV6 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-		2.88	2025-11-26	10.1101/2025.05.26.656101
	9KV8	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-	Go/β1/γ2	3.17	2025-11-26	10.1101/2025.05.26.656101
	9KV8 (No Gprot)	A	Peptide	Complement Peptide	C3a_B	Mus musculus	TLQP21	-		3.17	2025-11-26	10.1101/2025.05.26.656101

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9KZ8_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.