psnGPCR

Press and hold down the left mouse button and move the mouse to rotate.
Press and hold down the central mouse button and move the mouse to translate.
Use the mouse wheel to zoom in or out.
Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:D116	18.59	Yes	Yes	1	0	8
2	L:L:?1	R:R:V117	8.59	Yes	No	0	0	8
3	L:L:?1	R:R:C120	4.58	Yes	No	1	0	7
4	L:L:?1	R:R:T121	4.25	Yes	Yes	0	0	8
5	L:L:?1	R:R:I189	7.2	Yes	No	0	0	6
6	L:L:?1	R:R:S199	6.49	Yes	No	0	0	8
7	L:L:?1	R:R:F361	25.46	Yes	Yes	1	0	8
8	L:L:?1	R:R:F362	8.78	Yes	Yes	1	0	7
9	L:L:?1	R:R:Y390	14.37	Yes	Yes	1	0	8
10	R:R:Q36	R:R:V98	5.73	No	Yes	0	4	6
11	R:R:S40	R:R:V98	6.46	No	Yes	0	5	6
12	R:R:L43	R:R:W387	18.22	No	No	0	7	8
13	R:R:G44	R:R:I47	3.53	No	No	0	4	7
14	R:R:I47	R:R:L90	7.14	No	No	0	7	8
15	R:R:L83	R:R:V51	4.47	Yes	No	0	8	7
16	R:R:G53	R:R:Y402	4.35	No	Yes	0	9	6
17	R:R:D82	R:R:N54	8.08	Yes	Yes	0	9	9
18	R:R:L83	R:R:N54	4.12	Yes	Yes	0	8	9
19	R:R:N54	R:R:P397	6.52	Yes	No	0	9	9
20	R:R:C56	R:R:Y402	4.03	No	Yes	0	8	6
21	R:R:P397	R:R:V57	3.53	No	Yes	0	9	9
22	R:R:A401	R:R:V57	5.09	No	Yes	0	8	9
23	R:R:V57	R:R:Y402	5.05	Yes	Yes	0	9	6
24	R:R:V58	R:R:V80	6.41	No	No	0	7	7
25	R:R:A60	R:R:F411	5.55	No	No	0	8	8
26	R:R:I61	R:R:L67	4.28	No	Yes	4	8	8
27	R:R:F407	R:R:I61	6.28	Yes	No	4	8	8
28	R:R:E64	R:R:K413	9.45	No	No	0	7	6
29	R:R:E64	R:R:I414	8.2	No	No	0	7	7
30	R:R:L67	R:R:N72	6.87	Yes	No	4	8	9
31	R:R:F407	R:R:L67	6.09	Yes	Yes	4	8	8
32	R:R:Q68	R:R:Y73	6.76	No	No	0	8	6
33	R:R:N69	R:R:N72	10.9	No	No	0	8	9
34	R:R:R148	R:R:V70	14.38	Yes	No	0	8	7
35	R:R:P150	R:R:V70	5.3	No	No	0	5	7
36	R:R:F407	R:R:N72	12.08	Yes	No	4	8	9
37	R:R:P150	R:R:Y73	5.56	No	No	0	5	6
38	R:R:D133	R:R:L74	5.43	No	No	0	9	8
39	R:R:L156	R:R:L74	5.54	No	No	0	6	8
40	R:R:I75	R:R:Y400	6.04	No	Yes	0	8	9
41	R:R:H126	R:R:S77	6.97	Yes	No	1	8	9
42	R:R:I157	R:R:S77	10.84	No	No	1	8	9
43	R:R:D82	R:R:L78	8.14	Yes	Yes	1	9	9
44	R:R:H126	R:R:L78	6.43	Yes	Yes	1	8	9
45	R:R:L127	R:R:L78	5.54	Yes	Yes	1	8	9
46	R:R:I130	R:R:L78	4.28	No	Yes	1	9	9
47	R:R:L78	R:R:N396	12.36	Yes	Yes	1	9	9
48	R:R:L78	R:R:Y400	4.69	Yes	Yes	1	9	9
49	R:R:S122	R:R:T81	6.4	No	No	1	8	9
50	R:R:H126	R:R:T81	12.32	Yes	No	1	8	9
51	R:R:T81	R:R:W161	9.7	No	Yes	1	9	9
52	R:R:D82	R:R:S123	5.89	Yes	No	0	9	9
53	R:R:D82	R:R:S393	4.42	Yes	No	0	9	9
54	R:R:D82	R:R:N396	9.42	Yes	Yes	1	9	9
55	R:R:M84	R:R:W161	4.65	No	Yes	0	7	9
56	R:R:S393	R:R:V85	6.46	No	No	0	9	8
57	R:R:L115	R:R:L88	5.54	No	No	0	5	6
58	R:R:D116	R:R:V89	7.3	Yes	No	1	8	8
59	R:R:V89	R:R:Y390	3.79	No	Yes	1	8	8
60	R:R:L90	R:R:Y390	8.21	No	Yes	0	8	8
61	R:R:M92	R:R:W102	4.65	No	Yes	2	6	9
62	R:R:F112	R:R:M92	12.44	No	No	2	6	6
63	R:R:A93	R:R:Y390	4	No	Yes	0	7	8
64	R:R:L95	R:R:L99	5.54	No	No	0	6	5
65	R:R:W102	R:R:Y96	11.58	Yes	Yes	2	9	6
66	R:R:C187	R:R:Y96	4.03	Yes	Yes	2	9	6
67	R:R:A383	R:R:Q97	4.55	No	No	0	6	7
68	R:R:Q97	R:R:W387	8.76	No	No	0	7	8
69	R:R:L99	R:R:T103	7.37	No	No	0	5	5
70	R:R:K101	R:R:T103	6.01	No	No	0	5	5
71	R:R:D185	R:R:K101	16.59	No	No	0	4	5
72	R:R:L104	R:R:W102	10.25	No	Yes	2	7	9
73	R:R:T108	R:R:W102	4.85	No	Yes	2	6	9
74	R:R:C109	R:R:W102	6.53	Yes	Yes	2	9	9
75	R:R:F112	R:R:W102	9.02	No	Yes	2	6	9
76	R:R:C187	R:R:W102	10.45	Yes	Yes	2	9	9
77	R:R:L104	R:R:T108	8.84	No	No	2	7	6
78	R:R:D110	R:R:Q106	11.75	No	No	0	7	4
79	R:R:C109	R:R:C187	7.28	Yes	Yes	2	9	9
80	R:R:L111	R:R:L115	6.92	No	No	0	5	5
81	R:R:C120	R:R:D116	4.67	No	Yes	1	7	8
82	R:R:D116	R:R:Y390	11.49	Yes	Yes	1	8	8
83	R:R:L118	R:R:W161	6.83	No	Yes	0	6	9
84	R:R:F165	R:R:L118	14.61	No	No	0	5	6
85	R:R:L118	R:R:S168	4.5	No	No	0	6	8
86	R:R:C120	R:R:W358	5.22	No	Yes	1	7	8
87	R:R:G164	R:R:T121	3.64	No	Yes	0	8	8
88	R:R:I167	R:R:T121	6.08	No	Yes	0	8	8
89	R:R:A203	R:R:T121	5.03	No	Yes	0	8	8
90	R:R:H126	R:R:S122	6.97	Yes	No	1	8	8
91	R:R:S122	R:R:W161	19.77	No	Yes	1	8	9
92	R:R:F354	R:R:I124	5.02	Yes	No	1	9	8
93	R:R:I124	R:R:W358	12.92	No	Yes	1	8	8
94	R:R:C128	R:R:W125	3.92	Yes	Yes	1	7	7
95	R:R:I163	R:R:W125	19.97	No	Yes	0	5	7
96	R:R:I206	R:R:W125	3.52	No	Yes	0	6	7
97	R:R:P207	R:R:W125	16.21	No	Yes	1	9	7
98	R:R:H126	R:R:I157	7.95	Yes	No	1	8	8
99	R:R:H126	R:R:T160	20.54	Yes	No	1	8	8
100	R:R:H126	R:R:W161	5.29	Yes	Yes	1	8	9
101	R:R:L127	R:R:M211	5.65	Yes	Yes	1	8	9
102	R:R:F354	R:R:L127	4.87	Yes	Yes	1	9	8
103	R:R:L127	R:R:N396	12.36	Yes	Yes	1	8	9
104	R:R:L127	R:R:Y400	7.03	Yes	Yes	1	8	9
105	R:R:C128	R:R:P207	3.77	Yes	No	1	7	9
106	R:R:C128	R:R:M211	4.86	Yes	Yes	1	7	9
107	R:R:A129	R:R:L156	6.3	No	No	0	8	6
108	R:R:I130	R:R:R134	7.52	No	Yes	1	9	9
109	R:R:I130	R:R:Y400	10.88	No	Yes	1	9	9
110	R:R:A131	R:R:Y215	6.67	No	Yes	0	9	9
111	R:R:L132	R:R:W136	18.22	No	No	0	6	5
112	R:R:L132	R:R:L214	4.15	No	No	0	6	7
113	R:R:D133	R:R:R148	11.91	No	Yes	0	9	8
114	R:R:R134	R:R:Y215	8.23	Yes	Yes	1	9	9
115	R:R:I350	R:R:R134	3.76	No	Yes	1	8	9
116	R:R:R134	R:R:Y400	6.17	Yes	Yes	1	9	9
117	R:R:W136	R:R:Y135	4.82	No	Yes	0	5	9
118	R:R:T139	R:R:Y135	14.98	No	Yes	0	8	9
119	R:R:L214	R:R:Y135	5.86	No	Yes	0	7	9
120	R:R:R217	R:R:Y135	16.46	No	Yes	0	7	9
121	R:R:I218	R:R:Y135	3.63	No	Yes	0	9	9
122	R:R:D140	R:R:D143	9.31	No	No	0	7	6
123	R:R:D143	R:R:K147	4.15	No	No	0	6	5
124	R:R:D143	R:R:R152	11.91	No	No	0	6	7
125	R:R:R148	R:R:Y144	15.43	Yes	No	0	8	8
126	R:R:R148	R:R:R152	4.26	Yes	No	0	8	7
127	R:R:T160	R:R:W161	4.85	No	Yes	1	8	9
128	R:R:L162	R:R:L166	6.92	No	No	0	5	5
129	R:R:I167	R:R:Y198	4.84	No	No	0	8	5
130	R:R:P170	R:R:P171	5.84	Yes	Yes	3	8	7
131	R:R:P170	R:R:Y195	5.56	Yes	Yes	3	8	8
132	R:R:P170	R:R:Y198	5.56	Yes	No	0	8	5
133	R:R:P171	R:R:R176	4.32	Yes	No	3	7	6
134	R:R:P171	R:R:S190	3.56	Yes	Yes	3	7	6
135	R:R:P171	R:R:Y195	11.13	Yes	Yes	3	7	8
136	R:R:D192	R:R:W175	4.47	No	No	0	6	6
137	R:R:R176	R:R:S190	3.95	No	Yes	3	6	6
138	R:R:I189	R:R:Y195	7.25	No	Yes	0	6	8
139	R:R:D192	R:R:S190	7.36	No	Yes	0	6	6
140	R:R:S190	R:R:Y195	7.63	Yes	Yes	3	6	8
141	R:R:F370	R:R:H193	22.63	No	No	0	5	4
142	R:R:E372	R:R:H193	8.62	No	No	0	3	4
143	R:R:S199	R:R:Y195	11.45	No	Yes	0	8	8
144	R:R:P369	R:R:T196	12.24	No	No	0	7	7
145	R:R:F370	R:R:I197	3.77	No	No	0	5	7
146	R:R:T200	R:R:Y205	3.75	Yes	Yes	1	7	7
147	R:R:F362	R:R:T200	5.19	Yes	Yes	1	7	7
148	R:R:L366	R:R:T200	5.9	No	Yes	1	7	7
149	R:R:F201	R:R:Y205	8.25	No	Yes	1	5	7
150	R:R:F201	R:R:L366	4.87	No	No	1	5	7
151	R:R:G202	R:R:I206	3.53	No	No	0	5	6
152	R:R:F204	R:R:Y205	9.28	Yes	Yes	1	8	7
153	R:R:F204	R:R:L208	9.74	Yes	No	1	8	7
154	R:R:F204	R:R:F354	7.5	Yes	Yes	1	8	9
155	R:R:F204	R:R:W358	5.01	Yes	Yes	1	8	8
156	R:R:F204	R:R:L359	7.31	Yes	No	0	8	7
157	R:R:F204	R:R:F362	21.43	Yes	Yes	1	8	7
158	R:R:L366	R:R:Y205	5.86	No	Yes	1	7	7
159	R:R:F354	R:R:L208	3.65	Yes	No	1	9	7
160	R:R:M211	R:R:Y215	3.59	Yes	Yes	1	9	9
161	R:R:M211	R:R:M351	4.33	Yes	Yes	1	9	8
162	R:R:F354	R:R:M211	11.2	Yes	Yes	1	9	9
163	R:R:L212	R:R:M351	4.24	No	Yes	0	6	8
164	R:R:R217	R:R:V213	3.92	No	No	0	7	5
165	R:R:I218	R:R:Y215	7.25	No	Yes	0	9	9
166	R:R:L347	R:R:Y215	7.03	No	Yes	0	8	9
167	R:R:I350	R:R:Y215	8.46	No	Yes	1	8	9
168	R:R:M351	R:R:Y215	5.99	Yes	Yes	1	8	9
169	R:R:R217	R:R:R220	7.46	No	No	0	7	5
170	R:R:F219	R:R:R223	6.41	Yes	No	0	6	7
171	R:R:F219	R:R:L347	3.65	Yes	No	0	6	8
172	R:R:A222	R:R:T343	5.03	No	No	0	8	8
173	R:R:R223	R:R:R227	13.86	No	No	0	7	6
174	R:R:F224	R:R:K228	17.37	No	No	0	6	5
175	R:R:K228	R:R:R225	9.9	No	No	0	5	7
176	R:R:I226	R:R:R339	5.01	No	No	0	6	7
177	R:R:E340	R:R:I226	8.2	No	No	0	8	6
178	R:R:E340	R:R:R227	8.14	No	No	0	8	6
179	R:R:R339	R:R:T229	3.88	No	No	0	7	4
180	R:R:E330	R:R:R333	4.65	No	No	0	4	4
181	R:R:M335	R:R:R339	8.69	No	No	0	4	7
182	R:R:I349	R:R:K345	4.36	No	No	0	7	7
183	R:R:F403	R:R:I349	3.77	No	No	0	8	7
184	R:R:L395	R:R:T353	4.42	No	No	0	6	7
185	R:R:I399	R:R:T353	9.12	No	No	0	8	7
186	R:R:F354	R:R:W358	5.01	Yes	Yes	1	9	8
187	R:R:C357	R:R:N392	6.3	No	No	0	8	9
188	R:R:F361	R:R:W358	6.01	Yes	Yes	1	8	8
189	R:R:F362	R:R:W358	6.01	Yes	Yes	1	7	8
190	R:R:G389	R:R:W358	8.44	No	Yes	0	8	8
191	R:R:N392	R:R:W358	14.69	No	Yes	0	9	8
192	R:R:I363	R:R:L359	7.14	No	No	0	7	7
193	R:R:F361	R:R:F362	12.86	Yes	Yes	1	8	7
194	R:R:A365	R:R:F361	4.16	No	Yes	0	8	8
195	R:R:F361	R:R:I385	3.77	Yes	Yes	0	8	6
196	R:R:F361	R:R:N386	6.04	Yes	No	0	8	7
197	R:R:M377	R:R:V364	6.09	Yes	No	0	4	6
198	R:R:L368	R:R:M377	8.48	No	Yes	0	4	4
199	R:R:C371	R:R:C375	7.28	No	Yes	5	5	4
200	R:R:M377	R:R:P378	5.03	Yes	No	6	4	7
201	R:R:L381	R:R:M377	4.24	No	Yes	6	6	4
202	R:R:L381	R:R:P378	9.85	No	No	6	6	7
203	R:R:I384	R:R:L380	4.28	No	No	0	4	3
204	R:R:I385	R:R:L381	4.28	Yes	No	0	6	6
205	R:R:W387	R:R:Y390	16.4	No	Yes	0	8	8
206	R:R:N392	R:R:N396	12.26	No	Yes	0	9	9
207	R:R:F403	R:R:V398	3.93	No	No	0	8	6
208	R:R:I399	R:R:Y400	7.25	No	Yes	0	8	9
209	R:R:A401	R:R:F407	8.32	No	Yes	0	8	8
210	R:R:F411	R:R:Y402	7.22	No	Yes	0	8	6
211	R:R:D406	R:R:N404	5.39	No	No	0	7	9
212	R:R:F407	R:R:N404	7.25	Yes	No	0	8	9
213	R:R:P150	R:R:T149	3.5	No	No	0	5	8
214	R:R:C371	R:R:S374	3.44	No	No	5	5	5
215	R:R:C375	R:R:S374	3.44	Yes	No	5	4	5
216	R:R:A50	R:R:S86	3.42	No	No	0	8	8
217	R:R:C119	R:R:V85	3.42	No	No	0	7	8
218	R:R:A79	R:R:V57	3.39	No	Yes	0	9	9
219	R:R:I169	R:R:P170	3.39	No	Yes	0	6	8
220	R:R:I385	R:R:P360	3.39	Yes	No	0	6	9
221	R:R:K191	R:R:P369	3.35	No	No	0	5	7
222	R:R:C109	R:R:I113	3.27	Yes	No	2	9	7
223	R:R:C187	R:R:I113	3.27	Yes	No	2	9	7
224	R:R:A114	R:R:M172	3.22	No	No	0	7	6
225	R:R:D140	R:R:P141	3.22	No	No	0	7	8
226	R:R:C56	R:R:L52	3.17	No	No	0	8	4
227	R:R:C128	R:R:L210	3.17	Yes	No	0	7	7
228	R:R:A94	R:R:L43	3.15	No	No	0	7	7
229	R:R:A50	R:R:L394	3.15	No	No	0	8	7
230	R:R:A55	R:R:L83	3.15	No	Yes	0	5	8
231	R:R:A410	R:R:L67	3.15	No	Yes	0	8	8
232	R:R:A153	R:R:L74	3.15	No	No	0	7	8
233	R:R:T196	R:R:T200	3.14	No	Yes	0	7	7
234	R:R:C109	R:R:D110	3.11	Yes	No	0	9	7
235	R:R:A410	R:R:E64	3.02	No	No	0	8	7
236	R:R:L67	R:R:S66	3	Yes	No	0	8	6
237	R:R:R152	R:R:W136	3	No	No	0	7	5
238	R:R:L41	R:R:V37	2.98	No	No	0	4	5
239	R:R:N54	R:R:S86	2.98	Yes	No	0	9	8
240	R:R:L83	R:R:V87	2.98	Yes	No	0	8	6
241	R:R:L88	R:R:V87	2.98	No	No	0	6	6
242	R:R:N146	R:R:V145	2.96	No	No	0	5	6
243	R:R:L43	R:R:T39	2.95	No	No	0	7	5
244	R:R:I138	R:R:I218	2.94	No	No	0	9	9
245	R:R:I349	R:R:I399	2.94	No	No	0	7	8
246	R:R:I355	R:R:M351	2.92	No	Yes	0	7	8
247	R:R:F370	R:R:P369	2.89	No	No	0	5	7
248	R:R:I38	R:R:L42	2.85	No	No	0	3	5
249	R:R:I414	R:R:L63	2.85	No	No	0	7	6
250	R:R:I142	R:R:N146	2.83	No	No	0	6	5
251	R:R:K147	R:R:N146	2.8	No	No	0	5	5
252	R:R:L394	R:R:L46	2.77	No	No	0	7	7
253	R:R:A93	R:R:F112	2.77	No	No	0	7	6
254	R:R:D110	R:R:M172	2.77	No	No	0	7	6
255	R:R:D406	R:R:K405	2.77	No	No	0	7	6
256	R:R:A137	R:R:Y144	2.67	No	No	0	8	8
257	R:R:F219	R:R:T343	2.59	Yes	No	0	6	8
258	R:R:K334	R:R:R333	2.48	No	No	0	5	4
259	R:R:F48	R:R:L52	2.44	No	No	0	4	4
260	R:R:Q68	R:R:R65	2.34	No	No	0	8	7
261	R:R:A79	R:R:G76	1.95	No	No	0	9	6
262	R:R:G105	R:R:T108	1.82	No	No	0	7	6
263	R:R:G382	R:R:I385	1.76	No	Yes	0	4	6
264	R:R:G174	R:R:L173	1.71	No	No	0	5	6
265	R:R:C371	R:R:V367	1.71	No	No	5	5	6
266	R:R:C375	R:R:V367	1.71	Yes	No	5	4	6
267	R:R:G389	R:R:L388	1.71	No	No	0	8	8
268	R:R:A79	R:R:V58	1.7	No	No	0	9	7
269	R:R:C49	R:R:T45	1.69	No	No	0	5	4
270	R:R:I47	R:R:P91	1.69	No	No	0	7	9
271	R:R:A221	R:R:T139	1.68	No	No	0	6	8
272	R:R:A336	R:R:I226	1.62	No	No	0	5	6
273	R:R:T39	R:R:V98	1.59	No	Yes	0	5	6
274	R:R:C49	R:R:L394	1.59	No	No	0	5	7
275	R:R:C375	R:R:L368	1.59	Yes	No	0	4	4
276	R:R:A59	R:R:L63	1.58	No	No	0	5	6
277	R:R:A336	R:R:L337	1.58	No	No	0	5	5
278	R:R:A71	R:R:N69	1.56	No	No	0	8	8
279	R:R:A329	R:R:N328	1.56	No	No	0	5	3
280	R:R:I38	R:R:S34	1.55	No	No	0	3	3
281	R:R:I350	R:R:T346	1.52	No	No	0	8	8
282	R:R:F219	R:R:G216	1.51	Yes	No	0	6	3
283	R:R:L46	R:R:S391	1.5	No	No	0	7	5
284	R:R:K342	R:R:T346	1.5	No	No	0	8	8
285	R:R:L99	R:R:V98	1.49	No	Yes	0	5	6
286	R:R:L380	R:R:T379	1.47	No	No	0	3	2
287	R:R:E372	R:R:S373	1.44	No	No	0	3	3
288	R:R:I169	R:R:L173	1.43	No	No	0	6	6
289	R:R:K332	R:R:N328	1.4	No	No	0	6	3
290	R:R:A155	R:R:R151	1.38	No	No	0	3	6
291	R:R:L159	R:R:L162	1.38	No	No	0	3	5
292	R:R:K405	R:R:Q408	1.36	No	No	0	6	9
293	R:R:A186	R:R:Y96	1.33	No	Yes	0	4	6
294	R:R:N100	R:R:Q36	1.32	No	No	0	5	4
295	R:R:F219	R:R:V344	1.31	Yes	No	0	6	8
296	R:R:R151	R:R:T149	1.29	No	No	0	6	8
297	R:R:T188	R:R:Y96	1.25	No	Yes	0	5	6
298	R:R:L337	R:R:R333	1.21	No	No	0	5	4
299	R:R:L166	R:R:Y198	1.17	No	No	0	5	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg Int. Strength	Num Of Links	Community	ConSurf
1	L:L:?1	10.9233	9	1	0
2	R:R:N54	5.425	4	0	9
3	R:R:V57	4.265	4	0	9
4	R:R:L67	4.678	5	4	8
5	R:R:L78	6.90667	6	1	9
6	R:R:D82	7.19	5	1	9
7	R:R:L83	3.68	4	0	8
8	R:R:Y96	4.5475	4	2	6
9	R:R:V98	3.8175	4	0	6
10	R:R:W102	8.19	7	2	9
11	R:R:C109	5.0475	4	2	9
12	R:R:D116	10.5125	4	1	8
13	R:R:T121	4.75	4	0	8
14	R:R:W125	10.905	4	1	7
15	R:R:H126	9.49571	7	1	8
16	R:R:L127	7.09	5	1	8
17	R:R:C128	3.93	4	1	7
18	R:R:R134	6.42	4	1	9
19	R:R:Y135	9.15	5	0	9
20	R:R:R148	11.495	4	0	8
21	R:R:W161	8.515	6	1	9
22	R:R:P170	5.0875	4	3	8
23	R:R:P171	6.2125	4	3	7
24	R:R:C187	6.2575	4	2	9
25	R:R:S190	5.625	4	3	6
26	R:R:Y195	8.604	5	3	8
27	R:R:T200	4.495	4	1	7
28	R:R:F204	10.045	6	1	8
29	R:R:Y205	6.785	4	1	7
30	R:R:M211	5.926	5	1	9
31	R:R:Y215	6.74571	7	1	9
32	R:R:F219	3.094	5	0	6
33	R:R:M351	4.37	4	1	8
34	R:R:F354	6.20833	6	1	9
35	R:R:W358	7.91375	8	1	8
36	R:R:F361	9.71667	6	1	8
37	R:R:F362	10.854	5	1	7
38	R:R:C375	3.505	4	5	4
39	R:R:M377	5.96	4	6	4
40	R:R:I385	3.3	4	0	6
41	R:R:Y390	9.71	6	1	8
42	R:R:N396	11.6	4	1	9
43	R:R:Y400	7.01	6	1	9
44	R:R:Y402	5.1625	4	0	6
45	R:R:F407	8.004	5	4	8

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	L:L:?1	R:R:Y390	84.2069	14.37	Yes	Yes	1	0	8
2	R:R:W387	R:R:Y390	42.6948	16.4	No	Yes	0	8	8
3	R:R:L43	R:R:W387	34.399	18.22	No	No	0	7	8
4	R:R:L43	R:R:T39	28.8199	2.95	No	No	0	7	5
5	R:R:T39	R:R:V98	25.9674	1.59	No	Yes	0	5	6
6	R:R:L90	R:R:Y390	11.5193	8.21	No	Yes	0	8	8
7	L:L:?1	R:R:C120	40.2465	4.58	Yes	No	1	0	7
8	R:R:C120	R:R:W358	62.8247	5.22	No	Yes	1	7	8
9	R:R:N392	R:R:W358	65.1736	14.69	No	Yes	0	9	8
10	R:R:N392	R:R:N396	63.8484	12.26	No	Yes	0	9	9
11	R:R:D82	R:R:N396	63.0201	9.42	Yes	Yes	1	9	9
12	R:R:D82	R:R:N54	90.9787	8.08	Yes	Yes	0	9	9
13	R:R:L83	R:R:N54	14.7462	4.12	Yes	Yes	0	8	9
14	L:L:?1	R:R:F361	43.7152	25.46	Yes	Yes	1	0	8
15	R:R:F361	R:R:W358	48.6847	6.01	Yes	Yes	1	8	8
16	L:L:?1	R:R:F362	67.9499	8.78	Yes	Yes	1	0	7
17	R:R:F362	R:R:W358	45.7328	6.01	Yes	Yes	1	7	8
18	R:R:N54	R:R:P397	62.8512	6.52	Yes	No	0	9	9
19	R:R:P397	R:R:V57	60.923	3.53	No	Yes	0	9	9
20	R:R:V57	R:R:Y402	14.7462	5.05	Yes	Yes	0	9	6
21	R:R:A401	R:R:V57	37.2681	5.09	No	Yes	0	8	9
22	R:R:A401	R:R:F407	35.2538	8.32	No	Yes	0	8	8
23	R:R:F407	R:R:L67	16.7208	6.09	Yes	Yes	4	8	8
24	R:R:A410	R:R:L67	12.659	3.15	No	Yes	0	8	8
25	R:R:A410	R:R:E64	10.5652	3.02	No	No	0	8	7
26	R:R:F354	R:R:W358	91.6413	5.01	Yes	Yes	1	9	8
27	R:R:F354	R:R:M211	90.5546	11.2	Yes	Yes	1	9	9
28	R:R:M211	R:R:Y215	100	3.59	Yes	Yes	1	9	9
29	R:R:I218	R:R:Y215	80.3008	7.25	No	Yes	0	9	9
30	R:R:I218	R:R:Y135	76.2059	3.63	No	Yes	0	9	9
31	R:R:W136	R:R:Y135	58.8325	4.82	No	Yes	0	5	9
32	R:R:R152	R:R:W136	54.5322	3	No	No	0	7	5
33	R:R:R148	R:R:R152	36.8904	4.26	Yes	No	0	8	7
34	R:R:R148	R:R:V70	18.6523	14.38	Yes	No	0	8	7
35	R:R:P150	R:R:V70	16.3464	5.3	No	No	0	5	7
36	R:R:F204	R:R:F362	28.1441	21.43	Yes	Yes	1	8	7
37	R:R:F204	R:R:F354	33.1036	7.5	Yes	Yes	1	8	9
38	R:R:D133	R:R:R148	11.7049	11.91	No	Yes	0	9	8
39	R:R:F354	R:R:L127	34.7999	4.87	Yes	Yes	1	9	8
40	R:R:L127	R:R:Y400	14.4017	7.03	Yes	Yes	1	8	9
41	R:R:L127	R:R:L78	32.3218	5.54	Yes	Yes	1	8	9
42	R:R:H126	R:R:L78	33.6337	6.43	Yes	Yes	1	8	9
43	R:R:L78	R:R:N396	12.5696	12.36	Yes	Yes	1	9	9
44	R:R:I130	R:R:L78	15.0278	4.28	No	Yes	1	9	9
45	R:R:H126	R:R:W161	15.3359	5.29	Yes	Yes	1	8	9
46	R:R:A93	R:R:Y390	51.1198	4	No	Yes	0	7	8
47	R:R:A93	R:R:F112	48.4131	2.77	No	No	0	7	6
48	R:R:F112	R:R:W102	42.8373	9.02	No	Yes	2	6	9
49	R:R:L99	R:R:V98	14.4911	1.49	No	Yes	0	5	6
50	R:R:C109	R:R:W102	17.221	6.53	Yes	Yes	2	9	9
51	R:R:C109	R:R:D110	11.5326	3.11	Yes	No	0	9	7
52	L:L:?1	R:R:T121	18.1653	4.25	Yes	Yes	0	0	8
53	R:R:I167	R:R:T121	11.3769	6.08	No	Yes	0	8	8
54	R:R:C128	R:R:M211	13.4707	4.86	Yes	Yes	1	7	9
55	R:R:R134	R:R:Y400	15.601	6.17	Yes	Yes	1	9	9
56	R:R:R134	R:R:Y215	26.8453	8.23	Yes	Yes	1	9	9
57	R:R:D143	R:R:R152	16.3431	11.91	No	No	0	6	7
58	L:L:?1	R:R:I189	26.9215	7.2	Yes	No	0	0	6
59	R:R:I189	R:R:Y195	24.8012	7.25	No	Yes	0	6	8
60	R:R:P170	R:R:Y195	18.1918	5.56	Yes	Yes	3	8	8
61	L:L:?1	R:R:S199	27.117	6.49	Yes	No	0	0	8
62	R:R:S199	R:R:Y195	24.9006	11.45	No	Yes	0	8	8
63	R:R:S190	R:R:Y195	18.2282	7.63	Yes	Yes	3	6	8
64	R:R:F362	R:R:T200	12.1952	5.19	Yes	Yes	1	7	7
65	R:R:T196	R:R:T200	12.4006	3.14	No	Yes	0	7	7
66	R:R:P369	R:R:T196	10.8733	12.24	No	No	0	7	7
67	R:R:L347	R:R:Y215	41.2172	7.03	No	Yes	0	8	9
68	R:R:F219	R:R:L347	38.9743	3.65	Yes	No	0	6	8
69	R:R:F219	R:R:R223	27.6537	6.41	Yes	No	0	6	7
70	R:R:R223	R:R:R227	25.3711	13.86	No	No	0	7	6
71	R:R:E340	R:R:R227	23.0785	8.14	No	No	0	8	6
72	R:R:E340	R:R:I226	20.9482	8.2	No	No	0	8	6
73	R:R:A336	R:R:I226	11.7016	1.62	No	No	0	5	6
74	R:R:I399	R:R:Y400	12.3343	7.25	No	Yes	0	8	9
75	R:R:F361	R:R:I385	10.9296	3.77	Yes	Yes	0	8	6
76	R:R:N54	R:R:S86	14.7462	2.98	Yes	No	0	9	8
77	R:R:A50	R:R:S86	12.659	3.42	No	No	0	8	8
78	R:R:I169	R:R:P170	13.7126	3.39	No	Yes	0	6	8
79	R:R:A50	R:R:L394	10.5652	3.15	No	No	0	8	7
80	R:R:D116	R:R:Y390	21.2927	11.49	Yes	Yes	1	8	8
81	R:R:C120	R:R:D116	22.343	4.67	No	Yes	1	7	8
82	R:R:D82	R:R:L78	36.9997	8.14	Yes	Yes	1	9	9
83	R:R:L127	R:R:M211	26.6101	5.65	Yes	Yes	1	8	9
84	R:R:L127	R:R:N396	13.8716	12.36	Yes	Yes	1	8	9
85	R:R:I130	R:R:R134	12.7949	7.52	No	Yes	1	9	9
86	R:R:L78	R:R:Y400	14.5276	4.69	Yes	Yes	1	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
L:L:?1	R:R:D116	18.59	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:V117	8.59	1	Yes	No	0	8	0	1
L:L:?1	R:R:C120	4.58	1	Yes	No	0	7	0	1
L:L:?1	R:R:T121	4.25	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:I189	7.2	1	Yes	No	0	6	0	1
L:L:?1	R:R:S199	6.49	1	Yes	No	0	8	0	1
L:L:?1	R:R:F361	25.46	1	Yes	Yes	0	8	0	1
L:L:?1	R:R:F362	8.78	1	Yes	Yes	0	7	0	1
L:L:?1	R:R:Y390	14.37	1	Yes	Yes	0	8	0	1
R:R:D116	R:R:V89	7.3	1	Yes	No	8	8	1	2
R:R:V89	R:R:Y390	3.79	1	No	Yes	8	8	2	1
R:R:L90	R:R:Y390	8.21	0	No	Yes	8	8	2	1
R:R:A93	R:R:Y390	4	0	No	Yes	7	8	2	1
R:R:C120	R:R:D116	4.67	1	No	Yes	7	8	1	1
R:R:D116	R:R:Y390	11.49	1	Yes	Yes	8	8	1	1
R:R:C120	R:R:W358	5.22	1	No	Yes	7	8	1	2
R:R:G164	R:R:T121	3.64	0	No	Yes	8	8	2	1
R:R:I167	R:R:T121	6.08	0	No	Yes	8	8	2	1
R:R:A203	R:R:T121	5.03	0	No	Yes	8	8	2	1
R:R:I189	R:R:Y195	7.25	0	No	Yes	6	8	1	2
R:R:S199	R:R:Y195	11.45	0	No	Yes	8	8	1	2
R:R:F362	R:R:T200	5.19	1	Yes	Yes	7	7	1	2
R:R:F204	R:R:W358	5.01	1	Yes	Yes	8	8	2	2
R:R:F204	R:R:F362	21.43	1	Yes	Yes	8	7	2	1
R:R:F361	R:R:W358	6.01	1	Yes	Yes	8	8	1	2
R:R:F362	R:R:W358	6.01	1	Yes	Yes	7	8	1	2
R:R:F361	R:R:F362	12.86	1	Yes	Yes	8	7	1	1
R:R:A365	R:R:F361	4.16	0	No	Yes	8	8	2	1
R:R:F361	R:R:I385	3.77	1	Yes	Yes	8	6	1	2
R:R:F361	R:R:N386	6.04	1	Yes	No	8	7	1	2
R:R:W387	R:R:Y390	16.4	0	No	Yes	8	8	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

PDB Summary
PDB	9VJG_nogp
Class
SubFamily
Type
SubType
Species
Ligand
Other Ligand(s)
Protein Partners
PDB Resolution
Date
D.O.I.

Net Summary
I_min	3.52
Number of Linked Nodes	260
Number of Links	299
Number of Hubs	45
Number of Links mediated by Hubs	171
Number of Communities	6
Number of Nodes involved in Communities	62
Number of Links involved in Communities	97

Path Summary
Number Of Nodes in MetaPath	87
Number Of Links MetaPath	86
Number of Shortest Paths	86312
Length Of Smallest Path	3
Average Path Length	13.1938
Length of Longest Path	26
Minimum Path Strength	1.29
Average Path Strength	7.27128
Maximum Path Strength	22.025
Minimum Path Correlation	0.7
Average Path Correlation	0.928411
Maximum Path Correlation	0.99
Minimum % Of Corr. Nodes	5.26316
Average % Of Corr. Nodes	50.7201
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	56.7713
Maximum Path Hubs %	100

Annotation	Type	Links
Gene Ontology	Molecular Function	• cation binding • binding • ion binding • serotonin binding • amine binding • heterocyclic compound binding • small molecule binding • G protein-coupled amine receptor activity • G protein-coupled serotonin receptor activity • molecular transducer activity • G protein-coupled receptor activity • transmembrane signaling receptor activity • signaling receptor activity • Gi/o-coupled serotonin receptor activity • neurotransmitter receptor activity • serotonin receptor activity • protein binding • signaling receptor binding • receptor-receptor interaction • tetrapyrrole binding • heme binding • electron transfer activity • transition metal ion binding • iron ion binding • metal ion binding • cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction
Gene Ontology	Biological Process	• cellular response to stimulus • regulation of biological process • regulation of cellular process • response to stimulus • signaling • biological regulation • adenylate cyclase-inhibiting serotonin receptor signaling pathway • G protein-coupled serotonin receptor signaling pathway • cell communication • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • cellular process • signal transduction • behavior • multicellular organismal process • exploration behavior • regulation of amine metabolic process • dopamine metabolic process • primary metabolic process • catechol-containing compound metabolic process • regulation of primary metabolic process • amine metabolic process • catecholamine metabolic process • phenol-containing compound metabolic process • metabolic process • regulation of catecholamine metabolic process • regulation of metabolic process • biogenic amine metabolic process • regulation of dopamine metabolic process • adult behavior • regulation of tube diameter • system process • regulation of tube size • regulation of system process • circulatory system process • regulation of blood circulation • regulation of vasoconstriction • vascular process in circulatory system • regulation of multicellular organismal process • blood vessel diameter maintenance • regulation of biological quality • blood circulation • vasoconstriction • regulation of anatomical structure size • cell-cell signaling • gamma-aminobutyric acid signaling pathway • regulation of behavior • serotonin metabolic process • indole-containing compound metabolic process • cellular response to nitrogen compound • response to dopamine • serotonin receptor signaling pathway • cellular response to dopamine • response to monoamine • response to oxygen-containing compound • response to nitrogen compound • cellular response to oxygen-containing compound • cellular response to chemical stimulus • response to catecholamine • cellular response to monoamine stimulus • response to chemical • cellular response to catecholamine stimulus • cell population proliferation • positive regulation of cell population proliferation • regulation of cell population proliferation • positive regulation of biological process • positive regulation of cellular process • regulation of localization • regulation of hormone secretion • transport • hormone secretion • localization • regulation of secretion by cell • secretion by cell • signal release • regulation of signaling • regulation of transport • secretion • regulation of hormone levels • export from cell • establishment of localization • regulation of secretion • regulation of cell communication • hormone transport • monoamine transport • nitrogen compound transport • organic hydroxy compound transport • monoatomic ion transport • serotonin secretion • regulation of monoatomic ion transport • regulation of serotonin secretion • serotonin transport • trans-synaptic signaling • synaptic signaling • anterograde trans-synaptic signaling • chemical synaptic transmission • behavioral defense response • fear response • behavioral fear response • defense response • response to stress • multicellular organismal response to stress • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • electron transport chain • generation of precursor metabolites and energy • cell periphery • cellular anatomical structure • plasma membrane • membrane • somatodendritic compartment • cell projection • dendrite • dendritic tree • neuron projection • plasma membrane bounded cell projection • synapse • cell junction • periplasmic space • protein binding • binding • G-protein beta-subunit binding • fibroblast proliferation • adenylate cyclase-activating dopamine receptor signaling pathway • G protein-coupled dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • response to ketone • response to prostaglandin • response to lipid • response to endogenous stimulus • response to alcohol • cellular response to prostaglandin stimulus • cellular response to endogenous stimulus • cellular response to prostaglandin E stimulus • cellular response to alcohol • response to hormone • cellular response to lipid • response to prostaglandin E • cellular response to ketone • cellular response to hormone stimulus • protein-containing complex • extrinsic component of plasma membrane • catalytic complex • plasma membrane protein complex • cytoplasmic side of membrane • membrane protein complex • heterotrimeric G-protein complex • side of membrane • cytoplasmic side of plasma membrane • GTPase complex • extrinsic component of membrane • extrinsic component of cytoplasmic side of plasma membrane • extracellular exosome • membrane-bounded organelle • extracellular vesicle • extracellular organelle • extracellular region • organelle • extracellular space • vesicle • extracellular membrane-bounded organelle • enzyme binding • GTPase binding • protein-containing complex binding • pyrophosphatase activity • GTPase activity • ribonucleoside triphosphate phosphatase activity • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides • hydrolase activity • hydrolase activity, acting on acid anhydrides • catalytic activity • signaling receptor complex adaptor activity • protein-macromolecule adaptor activity • molecular adaptor activity • signaling adaptor activity • sensory perception of chemical stimulus • sensory perception • nervous system process • sensory perception of taste • developmental process • sensory organ development • eye development • animal organ development • retina development in camera-type eye • visual system development • multicellular organism development • camera-type eye development • anatomical structure development • sensory system development • system development • small GTPase-mediated signal transduction • Ras protein signal transduction • intracellular signal transduction • intracellular signaling cassette • phospholipase C-activating G protein-coupled receptor signaling pathway • cellular response to acetylcholine • acetylcholine receptor signaling pathway • postsynaptic signal transduction • G protein-coupled acetylcholine receptor signaling pathway • response to acetylcholine • non-motile cilium • 9+0 non-motile cilium • cilium • photoreceptor disc membrane • photoreceptor outer segment • photoreceptor cell cilium • organelle membrane • intracellular anatomical structure • cytoplasm • cytosol • vacuolar membrane • lytic vacuole • vacuole • intracellular membrane-bounded organelle • intracellular organelle • lytic vacuole membrane • bounding membrane of organelle • lysosomal membrane • lysosome
Gene Ontology	Cellular Component
SCOP2	Domain Identifier	• Transducin (heterotrimeric G protein), gamma chain
SCOP2	Family Identifier	• Transducin (heterotrimeric G protein), gamma chain
Membrane Protein Annotations	-	• Orientations of Proteins in Membranes database (OPM) • Protein Data Bank of Transmembrane Proteins (PDBTM) • MemProtMD

Details about the values in these tables can be found in the corresponding documentation page .


Code	_L_
PDB Residues	L:L:?1
Environment Details	Open EMBL-EBI Page
Code	_L_
Name
Synonyms
Identifier
Formula
Molecular Weight
SMILES
PubChem
Formal Charge
Total Atoms
Total Chiral Atoms
Total Bonds
Total Aromatic Bonds


PDBsum	Open PDBsum Page
Chain	R
Protein	Receptor
UniProt	P08908
Sequence	>9VJG_nogp_Chain_R S Y Q V I T S L L L G T L I F C A V L G N A C V V A A I A L E R S L Q N V A N Y L I G S L A V T D L M V S V L V L P M A A L Y Q V L N K W T L G Q V T C D L F I A L D V L C C T S S I H L C A I A L D R Y W A I T D P I D Y V N K R T P R R A A A L I S L T W L I G F L I S I P P M L G W R P D A C T I S K D H G Y T I Y S T F G A F Y I P L L L M L V L Y G R I F R A A R F R I R K T R N A E A K R K M A L A R E R K T V K T L G I I M G T F I L C W L P F F I V A L V L P F C E S S C H M P T L L G A I I N W L G Y S N S L L N P V I Y A Y F N K D F Q N A F K K I W Click on each residue to open a popup with some information about it. ConSurf Conservation Grade (See documentation): n/a 1 2 3 4 5 6 7 8 9

This receptor, from the same or other species and bound to the same or other ligands, is also present in the following networks:
Show	PDB	Class	SubFamily	Type	SubType	Species	Orthosteric Ligand	Other Ligand(s)	Protein Partners	Resolution	Date	DOI
	7E2X	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	-	PtdIns4P	Gi1/β1/γ2	3	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2X (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	-	PtdIns4P		3	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Y	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Serotonin	PtdIns4P	Gi1/β1/γ2	3	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Y (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Serotonin	PtdIns4P		3	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Z	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Aripiprazole	PtdIns4P	Gi1/β1/γ2	3.1	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	7E2Z (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Aripiprazole	PtdIns4P		3.1	2021-04-14	doi.org/10.1038/s41586-021-03376-8
	8JSP	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Ulotaront	-	Gi1/β1/γ2	3.65	2023-11-15	doi.org/10.1038/s41586-023-06804-z
	8JSP (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Ulotaront	-		3.65	2023-11-15	doi.org/10.1038/s41586-023-06804-z
	8W8B	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	SEP-363856	-	Gi1/β1/γ2	3	2023-11-22	doi.org/10.1038/s41586-023-06775-1
	8W8B (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	SEP-363856	-		3	2023-11-22	doi.org/10.1038/s41586-023-06775-1
	8FY8	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P	Gi1/β1/γ1	2.79	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FY8 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P		2.79	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYE	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	4-F,5-MeO-PyrT	PtdIns4P	Gi1/β1/γ1	2.85	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYE (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	4-F,5-MeO-PyrT	PtdIns4P		2.85	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYL	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Vilazodone	PtdIns4P	Gi1/β1/γ1	2.94	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYL (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Vilazodone	PtdIns4P		2.94	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYT	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	LSD	PtdIns4P	Gi1/β1/γ1	2.64	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYT (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	LSD	PtdIns4P		2.64	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYX	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P	Gi1/β1/γ1	2.72	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8FYX (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P		2.72	2024-05-15	doi.org/10.1038/s41586-024-07403-2
	8PJK	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	ST171	-	Gi1/β1/γ1	2.4	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8PJK (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	ST171	-		2.4	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8PKM	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-	Gi1/β1/γ1	2.9	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8PKM (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-		2.9	2024-05-29	doi.org/10.1126/sciadv.adv9267
	8JT6	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	(R)-IHCH-7179	PtdIns4P	Gi1/β1/γ2	3	2024-02-28	doi.org/10.1016/j.cell.2024.02.034
	8JT6 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	(R)-IHCH-7179	PtdIns4P		3	2024-02-28	doi.org/10.1016/j.cell.2024.02.034
	9GL2	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-	Gs/β1/γ2	3.2	2025-07-02	doi.org/10.1126/sciadv.adv9267
	9GL2 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Befiradol	-		3.2	2025-07-02	doi.org/10.1126/sciadv.adv9267
	9DYD	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P	Go/β1/γ2	2.96	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYD (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P		2.96	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYE	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P	Go/β1/γ2	2.9	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYE (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P		2.9	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYF	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P	Gi1/β1/γ2	2.74	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9DYF (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Asenapine	PtdIns4P		2.74	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9MD1	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P	Gz/β1/γ2	3.03	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9MD1 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	PtdIns4P		3.03	2025-08-13	doi.org/10.1126/sciadv.adu9851
	9VJ5	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Gepirone	-	Go/β1/γ2	2.69	2025-11-12	To be published
	9VJ5 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Gepirone	-		2.69	2025-11-12	To be published
	9VJ6	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	F-15599	-	Gi3/β1/γ2	2.62	2025-11-12	To be published
	9VJ6 (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	F-15599	-		2.62	2025-11-12	To be published
	9VJE	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-	Go/β1/γ2	2.47	2025-11-12	To be published
	9VJE (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-		2.47	2025-11-12	To be published
	9VJF	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-	Gi3/β1/γ2	2.7	2025-11-12	To be published
	9VJF (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Buspirone	-		2.7	2025-11-12	To be published
	9VJG	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	8-OH-DPAT	-	chim(NtGi2-Gz)/β1/γ2	2.67	2025-11-12	To be published
	9VJG (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	8-OH-DPAT	-		2.67	2025-11-12	To be published
	9VMY	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	TMU4142	-	Go/β1/γ2	2.86	2025-11-12	To be published
	9VMY (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	TMU4142	-		2.86	2025-11-12	To be published
	9VNF	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Pindolol	-	Go/β1/γ2	2.74	2025-11-12	To be published
	9VNF (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Pindolol	-		2.74	2025-11-12	To be published
	9KVG	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P	Gi1/β1/γ2	2.63	2025-12-03	To be published
	9KVG (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	5-MeO-DMT	PtdIns4P		2.63	2025-12-03	To be published
	9KVH	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Cinobufotenine	PtdIns4P	Gi1/β1/γ2	2.59	2025-12-03	To be published
	9KVH (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Cinobufotenine	PtdIns4P		2.59	2025-12-03	To be published
	9KVI	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Bufotenin	PtdIns4P	Gi1/β1/γ2	2.54	2025-12-03	To be published
	9KVI (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	Bufotenin	PtdIns4P		2.54	2025-12-03	To be published
	9HYI	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	DP81	-	Gi1/β1/γ2	2.3	2026-01-21	To be published
	9HYI (No Gprot)	A	Amine	5-Hydroxytryptamine	5-HT_1A	Homo sapiens	DP81	-		2.3	2026-01-21	To be published

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download 9VJG_nogp.zip

You can click to copy the link of this page to easily come back here later

or use this QR code to link and share this page.

You can also read or download a guide explaining the meaning of all files and numerical data.